Detailed information for compound 1514115

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 374.341 | Formula: C19H18O8
  • H donors: 4 H acceptors: 6 LogP: 2.69 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@H](Cc1ccc(c(c1)O)O)OC(=O)C=Cc1ccc(c(c1)O)O
  • InChi: 1S/C19H18O8/c1-26-19(25)17(10-12-3-6-14(21)16(23)9-12)27-18(24)7-4-11-2-5-13(20)15(22)8-11/h2-9,17,20-23H,10H2,1H3/t17-/m1/s1
  • InChiKey: XHALVRQBZGZHFE-QGZVFWFLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni opsin-like receptor 0.0052 0.0317 0.0317
Leishmania major trypanothione reductase 0.0144 0.1167 0.3688
Trypanosoma brucei unspecified product 0.0037 0.018 0.0558
Onchocerca volvulus 0.0141 0.1144 0.5639
Loa Loa (eye worm) hypothetical protein 0.0095 0.0712 0.0712
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0075 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0359 0.3158 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0317 0.0317
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0317 0.0317
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0707 0.1432
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0044 0.0058
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0049 0.0292 0.9842
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0344 0.3024 0.6129
Brugia malayi sulfakinin receptor protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) matrixin family protein 0.0229 0.1956 0.1956
Echinococcus multilocularis sex peptide receptor 0.0052 0.0317 0.0419
Brugia malayi Dopamine receptor 0.0052 0.0317 0.0317
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0049 0.0292 0.0591
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0317 0.0317
Onchocerca volvulus 0.0052 0.0317 0.1561
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0054 0.0336 0.0336
Plasmodium falciparum thioredoxin reductase 0.0144 0.1167 0.3688
Trypanosoma cruzi metacaspase, putative 0.0022 0.0034 0.0093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0317 0.0317
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0252 0.0247
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0317 0.0317
Schistosoma mansoni alpha glucosidase 0.0036 0.017 0.017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0336 0.1051
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0359 0.3158 1
Onchocerca volvulus 0.0052 0.0317 0.1561
Onchocerca volvulus 0.0052 0.0317 0.1561
Brugia malayi follicle stimulating hormone receptor 0.0052 0.0317 0.0317
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0022 0.0034 0.0251
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0117 0.0914 0.111
Schistosoma mansoni immunophilin 0.0359 0.3158 0.3158
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0083 0.0603 0.0603
Schistosoma mansoni ap endonuclease 0.0018 0.0005 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0317 0.0642
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0111 0.0147
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Brugia malayi RE15519p 0.0052 0.0317 0.0317
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0296 0.0925
Brugia malayi Calcitonin receptor-like protein seb-1 0.0034 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0047 0.0273 0.0273
Brugia malayi Heterochromatin protein 1 0.0071 0.0488 0.0488
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0479 0.0634
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0317 0.0642
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0317 0.0642
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0317 0.0642
Echinococcus multilocularis caspase 8 0.0022 0.0034 0.0045
Trichomonas vaginalis ferritin, putative 0.0026 0.0077 0.0073
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0049 0.0292 0.035
Echinococcus granulosus caspase 0.0081 0.058 0.1176
Echinococcus multilocularis serotonin receptor 0.0052 0.0317 0.0419
Echinococcus granulosus dna polymerase kappa 0.0054 0.0336 0.0681
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0176 0.0356
Onchocerca volvulus 0.0052 0.0317 0.1561
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Leishmania major DNA polymerase eta, putative 0.0037 0.0182 0.0561
Onchocerca volvulus 0.0237 0.2029 1
Echinococcus granulosus dna polymerase eta 0.0075 0.0528 0.1069
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0296 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Onchocerca volvulus Cell death protein 3 homolog 0.0022 0.0034 0.0167
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.005 0.0296 0.0296
Echinococcus multilocularis geminin 0.0359 0.3163 0.4184
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0317 0.0317
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.032 0.032
Echinococcus multilocularis muscleblind protein 0.0456 0.4056 0.5365
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0196 0.0608
Loa Loa (eye worm) hypothetical protein 0.0141 0.1144 0.1144
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.1349 0.1349
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0302 0.0944
Echinococcus multilocularis expressed protein 0.0026 0.0077 0.0102
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0317 0.0317
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0049 0.0292 0.0688
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0359 0.3158 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0141 0.1144 0.114
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.005 0.0296 0.06
Echinococcus multilocularis dna polymerase eta 0.0075 0.0528 0.0698
Loa Loa (eye worm) hypothetical protein 0.0095 0.0712 0.0712
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0317 0.0642
Loa Loa (eye worm) hypothetical protein 0.0456 0.4056 0.4056
Echinococcus multilocularis survival motor neuron protein 1 0.0461 0.4101 0.5425
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.032 0.0424
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Echinococcus granulosus g protein coupled receptor 0.0052 0.0317 0.0642
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0201 0.099
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.005 0.0296 0.0925
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0141 0.1144 0.1144
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0317 0.0419
Brugia malayi Matrixin family protein 0.0095 0.0712 0.0712
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0049 0.0292 0.9842
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0229 0.1127
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0317 0.0419
Echinococcus granulosus jumonji domain containing protein 0.004 0.0205 0.0416
Mycobacterium leprae PROBABLE HYDROLASE 0.0115 0.0903 0.2636
Echinococcus granulosus caspase 3 0.0059 0.0381 0.0772
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0359 0.3158 0.3158
Onchocerca volvulus 0.0052 0.0317 0.1561
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0077 0.2488
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0317 0.0642
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.017 0.0166
Loa Loa (eye worm) hypothetical protein 0.0029 0.0101 0.0101
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.017 0.1426
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0317 0.0317
Schistosoma mansoni microtubule-associated protein tau 0.0475 0.4232 0.4232
Brugia malayi GnHR receptor homolog 0.0052 0.0317 0.0317
Mycobacterium tuberculosis Probable reductase 0.0328 0.2875 0.3502
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0336 0.0332
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Mycobacterium tuberculosis Probable lipase LipE 0.0141 0.1144 0.139
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0052 0.0317 0.0317
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0111 0.0914
Loa Loa (eye worm) hypothetical protein 0.0141 0.1144 0.1144
Onchocerca volvulus 0.0049 0.0292 0.1438
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0359 0.3158 0.3154
Entamoeba histolytica hypothetical protein 0.0093 0.0693 0.2183
Echinococcus granulosus fmrfamide receptor 0.0052 0.0317 0.0642
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.1349 0.2734
Brugia malayi glutathione reductase 0.0144 0.1167 0.1167
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0296 0.0925
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.003 0.003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0093 0.0693 0.0916
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0049 0.0291 0.0291
Echinococcus multilocularis thioredoxin glutathione reductase 0.0144 0.1167 0.1544
Trichomonas vaginalis set domain proteins, putative 0.0237 0.2029 0.2025
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0175 0.0355
Loa Loa (eye worm) MBCTL1 0.006 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0049 0.0292 0.0292
Echinococcus multilocularis ferritin 0.0026 0.0077 0.0102
Echinococcus granulosus zinc finger protein 0.0024 0.0053 0.0108
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0359 0.3158 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0317 0.0419
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0359 0.3158 0.4177
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0317 0.0317
Onchocerca volvulus 0.0049 0.0292 0.1438
Onchocerca volvulus 0.0052 0.0317 0.1561
Loa Loa (eye worm) hypothetical protein 0.0456 0.4056 0.4056
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0049 0.0049
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0317 0.0642
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0328 0.2875 0.3502
Schistosoma mansoni histamine h1 receptor 0.0052 0.0317 0.0317
Brugia malayi hypothetical protein 0.0051 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Onchocerca volvulus 0.0052 0.0317 0.1561
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0317 0.0317
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0218 0.0218
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0834 0.756 1
Loa Loa (eye worm) fli-1 protein 0.0211 0.1793 0.1793
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0705 0.0705
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0317 0.0642
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0371 0.327 0.4325
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0049 0.0292 0.0292
Trichomonas vaginalis fk506-binding protein, putative 0.0049 0.0292 0.0287
Trypanosoma brucei trypanothione reductase 0.0144 0.1167 0.3688
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0101 0.0204
Onchocerca volvulus 0.0095 0.071 0.3502
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0094 0.0089
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0344 0.3024 0.4001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0052 0.0317 0.0317
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.017 0.0526
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0317 0.0419
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0317 0.0642
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0175 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0034 0.0029
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0317 0.0317
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0317 0.0642
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0201 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0034 0.0029
Brugia malayi larval opioid receptor 0.0052 0.0317 0.0317
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0273 0.0273
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0049 0.0292 0.2469
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Giardia lamblia PHD finger protein 15 0.0029 0.0101 0.0305
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0077 0.0073
Brugia malayi TAR-binding protein 0.0083 0.0603 0.0603
Leishmania major DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Schistosoma mansoni ferritin 0.0026 0.0077 0.0077
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0077 0.0005
Loa Loa (eye worm) hypothetical protein 0.0051 0.0302 0.0302
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0317 0.0317
Plasmodium vivax thioredoxin reductase, putative 0.0144 0.1167 0.3688
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0049 0.0292 0.091
Mycobacterium ulcerans beta-lactamase 0.0141 0.1144 0.114
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0317 0.0419
Echinococcus granulosus tumor protein p63 0.0339 0.2976 0.6031
Onchocerca volvulus 0.0052 0.0317 0.1561
Brugia malayi RNA recognition motif domain containing protein 0.0083 0.0603 0.0603
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0479 0.0479
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0317 0.0317
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0488 0.0484
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0317 0.0317
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0371 0.327 0.327
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0117 0.0914 0.2886
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0182 0.0561
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) glutathione reductase 0.0144 0.1167 0.1167
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0365 0.3215 0.3916
Trypanosoma brucei hypothetical protein, conserved 0.0141 0.1144 0.3614
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0229 0.0224
Entamoeba histolytica deoxycytidyl transferase, putative 0.0054 0.0336 0.1051
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0054 0.0336 0.0404
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0914 0.121
Trypanosoma brucei unspecified product 0.0037 0.018 0.0558
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0252 0.2125
Leishmania major DNA polymerase eta, putative 0.0075 0.0528 0.1659
Loa Loa (eye worm) hypothetical protein 0.0141 0.1144 0.1144
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni caspase-3 (C14 family) 0.0081 0.058 0.058
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0317 0.0642
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0317 0.0419
Echinococcus granulosus thioredoxin glutathione reductase 0.0144 0.1167 0.2366
Brugia malayi Matrixin family protein 0.0095 0.0712 0.0712
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0904 0.8203 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.017 0.0166
Trypanosoma cruzi DNA polymerase eta, putative 0.0075 0.0528 0.1659
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0054 0.0336 0.0336
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0317 0.0317
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0365 0.3215 1
Brugia malayi neuropeptide F receptor 0.0052 0.0317 0.0317
Schistosoma mansoni apoferritin-2 0.0026 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Toxoplasma gondii thioredoxin reductase 0.0144 0.1167 1
Brugia malayi Bromodomain containing protein 0.0035 0.0156 0.0156
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.12 0.1587
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0296 1
Onchocerca volvulus 0.005 0.0294 0.145
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0081 0.058 0.1176
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0034
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0077 0.0089
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.005 0.0296 0.0925
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Echinococcus granulosus caspase 2 0.0022 0.0034 0.0068
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.005 0.0296 0.0392
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0157 0.0207
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.021 0.1784 0.236
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.017 0.0166
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0252 0.0247
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0317 0.0317
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.005 0.0296 1
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0317 0.0419
Schistosoma mansoni alpha-glucosidase 0.0141 0.1138 0.1138
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.0174 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Echinococcus granulosus sex peptide receptor 0.0052 0.0317 0.0642
Mycobacterium tuberculosis Conserved protein 0.0141 0.1144 0.139
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0371 0.327 0.6627
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0077 0.023
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0049 0.0292 0.091
Echinococcus granulosus microtubule associated protein 2 0.0475 0.4232 0.8577
Plasmodium falciparum phd finger protein, putative 0.0029 0.0101 0.0305
Brugia malayi chromobox protein homolog 3 0.004 0.0201 0.0201
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0141 0.1144 0.1144
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0328 0.2875 0.3502
Loa Loa (eye worm) hypothetical protein 0.0115 0.0903 0.0903
Loa Loa (eye worm) hypothetical protein 0.004 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0461 0.4101 0.4101
Leishmania major peptidylprolyl isomerase-like protein 0.0359 0.3158 1
Echinococcus granulosus neuropeptide s receptor 0.0551 0.4934 1
Echinococcus multilocularis tumor protein p63 0.0339 0.2976 0.3937
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0101 0.0827
Onchocerca volvulus 0.0031 0.0122 0.06
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.017 0.0526
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.01 0.076 0.076
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0914 0.091
Schistosoma mansoni hypothetical protein 0.0052 0.0317 0.0317
Onchocerca volvulus Matrix metalloproteinase homolog 0.021 0.178 0.8775
Giardia lamblia NADH oxidase lateral transfer candidate 0.005 0.0296 0.0925
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0317 0.1561
Echinococcus granulosus g protein coupled receptor 0.0052 0.0317 0.0642
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0141 0.1144 0.1144
Echinococcus granulosus neuropeptide receptor A26 0.0551 0.4934 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0034 0.0152 0.0152
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0317 0.0642
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Mycobacterium tuberculosis Probable hydrolase 0.0141 0.1144 0.139
Schistosoma mansoni transcription factor LCR-F1 0.0093 0.0693 0.0693
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni amine GPCR 0.0052 0.0317 0.0317
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0302 0.2559
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Echinococcus granulosus geminin 0.0359 0.3163 0.641
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0435 0.0881
Schistosoma mansoni hypothetical protein 0.0323 0.2823 0.2823
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0309 0.27 0.3572
Plasmodium falciparum metacaspase 1 0.0022 0.0034 0.0093
Leishmania major hypothetical protein, conserved 0.0141 0.1144 0.3614
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0049 0.0292 0.091
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Schistosoma mansoni ferritin 0.0026 0.0077 0.0077
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0141 0.1144 0.1144
Plasmodium falciparum glutathione reductase 0.005 0.0296 0.0925
Loa Loa (eye worm) hypothetical protein 0.005 0.0294 0.0294
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0317 0.0419
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.032 0.1579
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0317 0.0419
Loa Loa (eye worm) hypothetical protein 0.0052 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni biogenic amine receptor 0.0052 0.0317 0.0317
Schistosoma mansoni chromobox protein 0.0071 0.0488 0.0488
Schistosoma mansoni amine GPCR 0.0052 0.0317 0.0317
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0101 0.0101
Trichomonas vaginalis fk506 binding protein, putative 0.0049 0.0292 0.0287
Trypanosoma brucei metacaspase 0.0022 0.0034 0.0093
Echinococcus multilocularis chromobox protein 1 0.0071 0.0488 0.0646
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0176 0.0233
Loa Loa (eye worm) hypothetical protein 0.0309 0.27 0.27
Echinococcus granulosus neuropeptide receptor 0.0052 0.0317 0.0642
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0359 0.3158 0.3154
Onchocerca volvulus Alhambra homolog 0.0029 0.0101 0.0496
Schistosoma mansoni immunophilin 0.0359 0.3158 0.3158
Onchocerca volvulus Matrilysin homolog 0.021 0.178 0.8775
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0022 0.0034 0.0034
Schistosoma mansoni gabp alpha 0.007 0.0479 0.0479
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Brugia malayi Bromodomain containing protein 0.0081 0.058 0.058
Brugia malayi Matrixin family protein 0.0229 0.1956 0.1956
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Entamoeba histolytica hypothetical protein 0.0093 0.0693 0.2183
Loa Loa (eye worm) hypothetical protein 0.0034 0.0152 0.0152
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0034 0.0093
Plasmodium falciparum thioredoxin reductase 0.005 0.0296 0.0925
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0317 0.0317
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) RNA binding protein 0.0083 0.0603 0.0603
Echinococcus granulosus endonuclease exonuclease phosphatase 0.021 0.1784 0.3615
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0317 0.0642
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0336 0.0336
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0309 0.27 0.5472
Trichomonas vaginalis penicillin-binding protein, putative 0.0141 0.1144 0.114
Brugia malayi Matrixin family protein 0.0095 0.0712 0.0712
Mycobacterium tuberculosis Probable dehydrogenase 0.0328 0.2875 0.3502
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Echinococcus multilocularis caspase 3 0.0059 0.0381 0.0504
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0359 0.3158 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0317 0.0317
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0317 0.0642
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Trichomonas vaginalis mercuric reductase, putative 0.005 0.0296 0.0292
Trichomonas vaginalis D-aminoacylase, putative 0.0141 0.1144 0.114
Echinococcus granulosus survival motor neuron protein 1 0.0461 0.4101 0.8312
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.1763 0.1763
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0317 0.0419
Onchocerca volvulus 0.0094 0.0705 0.3473
Brugia malayi latrophilin 2 splice variant baaae 0.0023 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni ets-related 0.0211 0.1793 0.1793
Loa Loa (eye worm) hypothetical protein 0.006 0.0386 0.0386
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0052 0.0317 0.0419
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0101 0.0133
Mycobacterium ulcerans flavoprotein disulfide reductase 0.005 0.0296 0.0292
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0435 0.0575
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Mycobacterium ulcerans epoxide hydrolase EphA 0.0531 0.4755 0.4752
Schistosoma mansoni hypothetical protein 0.0094 0.0705 0.0705
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Onchocerca volvulus 0.0141 0.1144 0.5639
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0359 0.3158 0.3158
Trichomonas vaginalis esterase, putative 0.0141 0.1144 0.114
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0317 0.0419
Trypanosoma brucei metacaspase 5, putative 0.0022 0.0034 0.0093
Trichomonas vaginalis glutathione reductase, putative 0.005 0.0296 0.0292
Schistosoma mansoni immunophilin 0.0309 0.27 0.27
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0317 0.0642
Trichomonas vaginalis D-aminoacylase, putative 0.0141 0.1144 0.114
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Schistosoma mansoni survival motor neuron protein 0.0094 0.0705 0.0705
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0317 0.0419
Echinococcus granulosus expressed protein 0.0026 0.0077 0.0156
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0302 0.0944
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0328 0.2875 0.3502
Schistosoma mansoni hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0914 0.091
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0292 0.0287
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0317 0.0642
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0077 0.0089
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Trichomonas vaginalis fk506-binding protein, putative 0.0049 0.0292 0.0287
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0371 0.327 0.327
Schistosoma mansoni hypothetical protein 0.0052 0.0317 0.0317
Entamoeba histolytica hypothetical protein 0.0093 0.0693 0.2183
Brugia malayi jmjC domain containing protein 0.0094 0.0707 0.0707
Brugia malayi G-protein coupled receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0488 0.0488
Schistosoma mansoni hypothetical protein 0.0029 0.0101 0.0101
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0359 0.3158 1
Plasmodium vivax glutathione reductase, putative 0.0144 0.1167 0.3688
Onchocerca volvulus 0.0052 0.0317 0.1561
Echinococcus granulosus tar DNA binding protein 0.0083 0.0603 0.1221
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0317 0.0317
Trypanosoma brucei Metacaspase-4 0.0022 0.0034 0.0093
Schistosoma mansoni neuropeptide receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0031 0.0122 0.0122
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0336 0.1051
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0049 0.0292 0.0292
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Loa Loa (eye worm) beta-lactamase 0.0141 0.1144 0.1144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0141 0.1144 0.139
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0054 0.0336 0.1051
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0252 0.2125
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.005 0.0296 0.0925
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.1349 0.1349
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Brugia malayi RNA binding protein 0.0083 0.0603 0.0603
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0317 0.0419
Plasmodium falciparum metacaspase-like protein 0.0022 0.0034 0.0093
Echinococcus multilocularis caspase 2 0.0022 0.0034 0.0045
Toxoplasma gondii NADPH-glutathione reductase 0.005 0.0296 0.2508
Trichomonas vaginalis fk506-binding protein, putative 0.0359 0.3158 0.3154
Schistosoma mansoni tar DNA-binding protein 0.0083 0.0603 0.0603
Trypanosoma cruzi trypanothione reductase, putative 0.0144 0.1167 0.3688
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Echinococcus granulosus ferritin 0.0026 0.0077 0.0156
Plasmodium falciparum glutathione reductase 0.0144 0.1167 0.3688
Echinococcus granulosus peregrin 0.0035 0.0156 0.0316
Echinococcus multilocularis peregrin 0.0035 0.0156 0.0207
Schistosoma mansoni tar DNA-binding protein 0.0083 0.0603 0.0603
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0049 0.0098
Trichomonas vaginalis D-aminoacylase, putative 0.0141 0.1144 0.114
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.005 0.0296 0.2508
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0252 0.0784
Loa Loa (eye worm) hypothetical protein 0.0047 0.0273 0.0273
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0054 0.0336 0.0332
Echinococcus granulosus neuropeptide receptor 0.0052 0.0317 0.0642
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.018 0.0558
Schistosoma mansoni myosin xvIII 0.0052 0.0317 0.0317
Schistosoma mansoni bromodomain containing protein 0.0068 0.0469 0.0469
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0044 0.0089
Schistosoma mansoni opsin-like receptor 0.0052 0.0317 0.0317
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0317 0.0642
Brugia malayi Ets-domain containing protein 0.007 0.0479 0.0479
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0317 0.0642
Mycobacterium tuberculosis Conserved protein 0.0141 0.1144 0.139
Schistosoma mansoni ferritin 0.0026 0.0077 0.0077
Brugia malayi Pre-SET motif family protein 0.003 0.0111 0.0111
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0115 0.0903 0.0903
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0105 0.0808 0.0808
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.005 0.0296 0.0296
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0026 0.0076 0.0087
Mycobacterium tuberculosis Probable oxidoreductase 0.0365 0.3215 0.3916
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.005 0.0296 0.0925
Schistosoma mansoni hypothetical protein 0.0023 0.0044 0.0044
Onchocerca volvulus 0.0095 0.0712 0.3508
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0371 0.327 0.4325
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0317 0.0419
Schistosoma mansoni caspase-7 (C14 family) 0.0022 0.0034 0.0034
Onchocerca volvulus 0.0052 0.0317 0.1561
Echinococcus granulosus g protein coupled receptor 0.0052 0.0317 0.0642
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.12 0.12
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0049 0.0292 0.091
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0141 0.1144 0.139
Brugia malayi hypothetical protein 0.0093 0.0693 0.0693
Schistosoma mansoni neuropeptide receptor 0.0052 0.0317 0.0317
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0317 0.0642
Echinococcus multilocularis fk506 binding protein 0.0359 0.3158 0.4177
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0049 0.0292 0.091
Onchocerca volvulus 0.0052 0.0317 0.1561
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0292 0.0287
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Echinococcus granulosus somatostatin receptor 0.0052 0.0317 0.0642
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0388 0.0513
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.005 0.0296 0.0925
Schistosoma mansoni neuropeptide receptor 0.0052 0.0317 0.0317
Echinococcus granulosus tachykinin peptides receptor 99D 0.0052 0.0317 0.0642
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0388 0.0513
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0359 0.3158 0.6399
Onchocerca volvulus 0.0052 0.0317 0.1561
Echinococcus granulosus FK506 binding protein 2 0.0049 0.0292 0.0591
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0229 0.0224
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.005 0.0296 0.0356
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.018 0.0558
Giardia lamblia DINP protein human, muc B family 0.0054 0.0336 0.1051
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0317 0.0317
Echinococcus multilocularis neuropeptide receptor A26 0.0551 0.4934 0.6527
Loa Loa (eye worm) matrix metalloproteinase 0.0095 0.0712 0.0712
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0359 0.3158 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0296 0.0925
Echinococcus multilocularis beta LACTamase domain containing family member 0.0141 0.1144 0.1513
Loa Loa (eye worm) hypothetical protein 0.0022 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Entamoeba histolytica hypothetical protein 0.0093 0.0693 0.2183
Echinococcus multilocularis dna polymerase kappa 0.0054 0.0336 0.0445
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0317 0.0642
Leishmania major metacaspase, putative 0.0022 0.0034 0.0093
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0252 0.051
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0359 0.3158 1
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0479 0.0972
Plasmodium vivax metacaspase 1, putative 0.0022 0.0034 0.0093
Onchocerca volvulus 0.0141 0.1144 0.5639
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0101 0.0204
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0317 0.0642
Brugia malayi G-protein coupled receptor 0.0052 0.0317 0.0317
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.114 0.2309
Trypanosoma cruzi hypothetical protein, conserved 0.0141 0.1144 0.3614
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.032 0.0424
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Loa Loa (eye worm) matrixin family protein 0.021 0.178 0.178
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0317 0.0317
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0531 0.4755 0.5794
Onchocerca volvulus 0.0052 0.0317 0.1561
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0034 0.0152 0.0152
Trypanosoma brucei unspecified product 0.0054 0.0336 0.1051
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0317 0.0317
Schistosoma mansoni neuropeptide receptor 0.0052 0.0317 0.0317
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.017 0.017
Trichomonas vaginalis DNA polymerase eta, putative 0.0054 0.0336 0.0332
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0117 0.0914 0.0914
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0317 0.0419
Loa Loa (eye worm) hypothetical protein 0.0141 0.1144 0.1144
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0101 0.0827
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0359 0.3158 0.6399
Loa Loa (eye worm) TAR-binding protein 0.0083 0.0603 0.0603
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0076 0.0071
Onchocerca volvulus 0.0052 0.032 0.1579
Brugia malayi Pre-SET motif family protein 0.0208 0.1763 0.1763
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0328 0.2875 0.8919
Schistosoma mansoni tar DNA-binding protein 0.0083 0.0603 0.0603
Trypanosoma cruzi metacaspase 5, putative 0.0022 0.0034 0.0093
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0527 0.0527
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0388 0.0388
Brugia malayi Cell death protein 3 precursor 0.0022 0.0034 0.0034
Brugia malayi Ets-domain containing protein 0.007 0.0479 0.0479
Schistosoma mansoni hypothetical protein 0.0023 0.0051 0.0051
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0359 0.3158 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Trypanosoma cruzi metacaspase, putative 0.0022 0.0034 0.0093
Giardia lamblia Hypothetical protein 0.0049 0.0292 0.091
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0077 0.0073
Brugia malayi Dopamine receptor protein 1 0.0052 0.0317 0.0317
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.032 0.032
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0317 0.0642
Schistosoma mansoni hypothetical protein 0.0359 0.3163 0.3163
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0317 0.0419
Echinococcus granulosus serotonin receptor 0.0052 0.0317 0.0642
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Brugia malayi hypothetical protein 0.0033 0.0136 0.0136
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0317 0.0419
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1349 0.1785
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0296 0.0925
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0141 0.1144 0.114
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0094 0.0089
Schistosoma mansoni DNA polymerase eta 0.0075 0.0528 0.0528
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0317 0.0317
Onchocerca volvulus 0.0052 0.0317 0.1561
Leishmania major hypothetical protein, conserved 0.0051 0.0302 0.0944
Trypanosoma brucei metacaspase MCA3 0.0022 0.0034 0.0093
Trypanosoma cruzi metacaspase, putative 0.0022 0.0034 0.0093
Echinococcus granulosus allatostatin A receptor 0.0052 0.0317 0.0642
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0049 0.0292 0.0292
Mycobacterium ulcerans hydrolase 0.0115 0.0903 0.0899
Schistosoma mansoni alpha-glucosidase 0.0141 0.1138 0.1138
Brugia malayi Matrixin family protein 0.0095 0.0712 0.0712
Brugia malayi Serotonin receptor 0.0052 0.0317 0.0317
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0317 0.0419
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0034 0.0029
Echinococcus multilocularis zinc finger protein 0.0024 0.0053 0.007
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0022 0.0034 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.017 0.0166
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.017 0.0166
Schistosoma mansoni caspase-7 (C14 family) 0.0081 0.058 0.058
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Onchocerca volvulus 0.0052 0.0317 0.1561
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0051
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0093 0.0693 0.1404
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0359 0.3158 0.3154
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0317 0.0317
Schistosoma mansoni ferritin light chain 0.0026 0.0077 0.0077
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0005 0.0005
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.12 0.12
Brugia malayi ORL1-like opioid receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.005 0.0296 0.0292
Mycobacterium tuberculosis Conserved hypothetical protein 0.0054 0.0336 0.0404
Schistosoma mansoni amine GPCR 0.0052 0.0317 0.0317
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Brugia malayi hypothetical protein 0.0461 0.4101 0.4101
Echinococcus multilocularis serotonin receptor 0.0052 0.0317 0.0419
Mycobacterium ulcerans lipase LipD 0.0141 0.1144 0.114
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0049 0.0292 0.0386
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0049 0.0292 0.2469
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0359 0.3158 0.3158
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.032 0.0649
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0317 0.0642
Trypanosoma brucei glucosidase, putative 0.0036 0.017 0.0526
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0022 0.0034 0.0251
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0317 0.0419
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0371 0.327 0.327
Brugia malayi Dopamine receptor protein 2 0.0052 0.0317 0.0317
Echinococcus multilocularis tar DNA binding protein 0.0083 0.0603 0.0797
Echinococcus granulosus chromobox protein 1 0.0071 0.0488 0.0989
Loa Loa (eye worm) hypothetical protein 0.0141 0.1144 0.1144
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0388 0.0785
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0317 0.0419
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0034 0.0029
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0707 0.0935
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0101 0.0101
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0317 0.0419
Echinococcus multilocularis chromobox protein 1 0.0071 0.0488 0.0646
Schistosoma mansoni apoferritin-2 0.0026 0.0077 0.0077
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0175 0.0175
Plasmodium vivax hypothetical protein, conserved 0.0141 0.1144 0.3614
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0317 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0101 0.0305
Echinococcus granulosus caspase 8 0.0022 0.0034 0.0068
Schistosoma mansoni amine GPCR 0.0052 0.0317 0.0317
Brugia malayi G protein-coupled receptor 0.0052 0.0317 0.0317
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.017 0.0526
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0049 0.0292 0.2469
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0359 0.3158 1
Schistosoma mansoni adenoreceptor 0.0052 0.0317 0.0317
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0054 0.0336 0.0681
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0117 0.0914 0.0914
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0317 0.0419
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.017 0.0166
Loa Loa (eye worm) hypothetical protein 0.0141 0.1144 0.1144
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0317 0.0419
Loa Loa (eye worm) acetyltransferase 0.0147 0.12 0.12
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0317 0.0419
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0049 0.0064
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0317 0.0317
Trypanosoma brucei metacaspase MCA2 0.0022 0.0034 0.0093
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0317 0.0642
Plasmodium vivax SET domain protein, putative 0.003 0.0111 0.0337
Loa Loa (eye worm) hypothetical protein 0.0073 0.0506 0.0506
Echinococcus granulosus orexin receptor type 2 0.0052 0.0317 0.0642
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.017 0.0526
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.005 0.0296 0.0925
Schistosoma mansoni hypothetical protein 0.0049 0.0292 0.0292
Echinococcus multilocularis muscleblind protein 1 0.0456 0.4056 0.5365
Mycobacterium leprae conserved hypothetical protein 0.0141 0.1144 0.3404
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0317 0.0642
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.0174 0.0174
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0273 0.0361
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0317 0.0642
Treponema pallidum NADH oxidase 0.005 0.0296 0.0925
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0292
Echinococcus granulosus muscleblind protein 0.0456 0.4056 0.822
Loa Loa (eye worm) hypothetical protein 0.0095 0.0712 0.0712
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0302 0.0944
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0317 0.0317
Schistosoma mansoni hypothetical protein 0.0093 0.0693 0.0693
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0196 0.0608
Trypanosoma cruzi metacaspase 5, putative 0.0022 0.0034 0.0093
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0384 0.0384
Brugia malayi PHD-finger family protein 0.0029 0.0101 0.0101
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.017 0.0345
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0052 0.0317 0.0419
Loa Loa (eye worm) thioredoxin reductase 0.0144 0.1167 0.1167
Brugia malayi Fli-1 protein 0.0211 0.1793 0.1793
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0054 0.0336 0.0445
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0317 0.0419
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0294 0.0294
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.018 0.0558
Trypanosoma cruzi hypothetical protein, conserved 0.0141 0.1144 0.3614
Schistosoma mansoni chromobox protein 0.0071 0.0488 0.0488
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0111 0.0111
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.032 0.032
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0205 0.0271
Schistosoma mansoni tar DNA-binding protein 0.0083 0.0603 0.0603
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.017 0.0166
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0371 0.327 0.6627
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0296 0.0925
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0302 0.0944
Onchocerca volvulus Matrilysin homolog 0.0095 0.0712 0.3508
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0336 0.1051
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0022 0.0034 0.0251
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Schistosoma mansoni terminal deoxycytidyl transferase 0.0054 0.0336 0.0336
Schistosoma mansoni hypothetical protein 0.0052 0.0317 0.0317
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.017 0.0225
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0095 0.0712 0.0712
Schistosoma mansoni ferritin 0.0026 0.0077 0.0077
Schistosoma mansoni tar DNA-binding protein 0.0083 0.0603 0.0603
Echinococcus granulosus beta LACTamase domain containing family member 0.0141 0.1144 0.2319
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0115 0.0903 0.1096
Schistosoma mansoni hypothetical protein 0.0134 0.1078 0.1078
Mycobacterium tuberculosis Conserved protein 0.0141 0.1144 0.139
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Echinococcus multilocularis somatostatin receptor 0.0052 0.0317 0.0419
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0049 0.0292 0.091
Mycobacterium ulcerans esterase/lipase LipP 0.0141 0.1144 0.114
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0359 0.3158 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0201 0.0196
Onchocerca volvulus 0.0134 0.1078 0.5315
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.032 0.0649
Brugia malayi Thioredoxin reductase 0.0144 0.1167 0.1167
Echinococcus multilocularis caspase 0.0081 0.058 0.0768
Loa Loa (eye worm) FKBP5 protein 0.0359 0.3158 0.3158
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0365 0.3215 0.3916
Toxoplasma gondii ABC1 family protein 0.0141 0.1144 0.98
Loa Loa (eye worm) hypothetical protein 0.006 0.0388 0.0388
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0317 0.0642
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0328 0.2875 0.3502
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0388 0.0388
Brugia malayi beta-lactamase family protein 0.0141 0.1144 0.1144
Schistosoma mansoni biogenic amine receptor 0.0052 0.0317 0.0317
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0144 0.1167 0.1418
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Echinococcus granulosus hypothetical protein 0.0052 0.0317 0.0642
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0336 0.1051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0371 0.327 0.327
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.017 0.0526
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0182 0.1521
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0371 0.327 0.327
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0317 0.0317
Schistosoma mansoni fk506 binding protein 0.0049 0.0292 0.0292
Trichomonas vaginalis immunophilin, putative 0.0359 0.3158 0.3154
Brugia malayi Bromodomain containing protein 0.0043 0.0231 0.0231
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0336 0.0332
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.005 0.0296 0.0925
Echinococcus multilocularis 0.0049 0.0292 0.0386
Schistosoma mansoni hypothetical protein 0.0021 0.003 0.003
Brugia malayi Melatonin receptor type 1A 0.0052 0.0317 0.0317
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0302 0.0944
Schistosoma mansoni opsin-like receptor 0.0052 0.0317 0.0317
Leishmania major acetoin dehydrogenase e3 component-like protein 0.005 0.0296 0.0925
Loa Loa (eye worm) hypothetical protein 0.0045 0.0254 0.0254
Brugia malayi neuropeptide F receptor 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Echinococcus multilocularis neuropeptide s receptor 0.0551 0.4934 0.6527
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0317 0.0642
Leishmania major fk506-binding protein 1-like protein 0.0359 0.3158 1
Brugia malayi ImpB/MucB/SamB family protein 0.0075 0.0528 0.0528
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0141 0.1144 0.139
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0359 0.3158 0.3158
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0317 0.0419
Brugia malayi AKH receptor 0.0052 0.0317 0.0317
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1349 0.1785
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0049 0.0292 0.091
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0022 0.0034 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0317 0.0419
Echinococcus granulosus chromobox protein 1 0.0071 0.0488 0.0989
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.017 0.0166
Brugia malayi Hemopexin family protein 0.0134 0.1078 0.1078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0199 0.0199
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0049 0.0292 0.091
Mycobacterium leprae Probable lipase LipE 0.0141 0.1144 0.3404
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0488 0.0484
Schistosoma mansoni zinc finger protein 0.0024 0.0053 0.0053
Brugia malayi beta-lactamase family protein 0.0141 0.1144 0.1144
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0049 0.0292 0.0292
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0317 0.0317
Mycobacterium ulcerans hypothetical protein 0.0049 0.0292 0.0287
Brugia malayi mbt repeat family protein 0.0052 0.032 0.032
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0317 0.0419
Brugia malayi hypothetical protein 0.0052 0.0317 0.0317
Onchocerca volvulus 0.0041 0.0218 0.1074
Mycobacterium tuberculosis Probable lipase LipD 0.0141 0.1144 0.139
Schistosoma mansoni ferritin light chain 0.0026 0.0077 0.0077
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0317 0.1561
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0081 0.058 0.0768
Schistosoma mansoni ap endonuclease 0.0018 0.0005 0.0005
Trypanosoma cruzi metacaspase, putative 0.0022 0.0034 0.0093
Brugia malayi beta-lactamase 0.0141 0.1144 0.1144
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0292 0.091
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0049 0.0292 0.0292
Brugia malayi PHD-finger family protein 0.0029 0.0104 0.0104
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0296 0.0925
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.005 0.0296 0.0292
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0914 0.1853
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.017 0.0166
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Mycobacterium ulcerans hypothetical protein 0.0141 0.1144 0.114
Schistosoma mansoni biogenic amine receptor 0.0052 0.0317 0.0317
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.032 0.032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Schistosoma mansoni amine GPCR 0.0052 0.0317 0.0317
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0359 0.3158 1
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0317 0.0642
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0317 0.0317
Brugia malayi putative neuropeptide receptor 0.0052 0.0317 0.0317
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0317 0.0317
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0317 0.0419
Brugia malayi Muscleblind-like protein 0.0456 0.4056 0.4056
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0035 0.0035
Brugia malayi Serotonin receptor 0.0052 0.0317 0.0317
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0317 0.0419
Brugia malayi jmjC domain containing protein 0.0037 0.0175 0.0175
Trypanosoma brucei DNA polymerase eta, putative 0.0075 0.0528 0.1659
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0273 0.0553
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0317 0.0317
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0359 0.3158 1
Echinococcus multilocularis microtubule associated protein 2 0.0475 0.4232 0.5598
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0049 0.0292 0.2469
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0005 0.0006
Brugia malayi mbt repeat family protein 0.0052 0.032 0.032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0317 0.0317
Mycobacterium tuberculosis Probable esterase LipL 0.0141 0.1144 0.139
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0049 0.0292 0.091
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0388 0.0785
Onchocerca volvulus 0.0052 0.0317 0.1561
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0196 0.0608
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0302 0.0944
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0317 0.0642
Schistosoma mansoni hypothetical protein 0.0359 0.3163 0.3163
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0273 0.0273
Onchocerca volvulus 0.0052 0.0317 0.1561
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0317 0.0419
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0034 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0034 0.0029

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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