Detailed information for compound 1514438

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 8837.09 | Formula: C323H520N157O97P21S
  • H donors: 57 H acceptors: 72 LogP: -39.9 Rotable bonds: 210
    Rule of 5 violations (Lipinski): 4
  • SMILES: SC[C@@H](C(=O)N1CCN(CC1)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@@H]1CN(C[C@@H](O1)n1cnc2c1nc(N)[nH]c2=O)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@@H]1CN(C[C@@H](O1)n1ccc(nc1=O)N)P(=O)(N(C)C)OC[C@@H]1CN(C[C@@H](O1)n1cnc2c1ncnc2N)P(=O)(N(C)C)OC[C@H]1O[C@H](CN(C1)P(=O)(N(C)C)OC[C@@H]1CN(POC[C@H]2O[C@H](CN(C2)P(=O)(N(C)C)OC[C@H]2O[C@H](CN(C2)P(=O)(N(C)C)OC[C@H]2O[C@H](CN(C2)P(=O)(N(C)C)OC[C@H]2O[C@H](CN(C2)P(=O)(N(C)C)OC[C@H]2O[C@H](CN(C2)P(=O)(N(C)C)OC[C@H]2O[C@H](CN(C2)P(=O)(N(C)C)OC[C@H]2O[C@H](CN(C2)P(=O)(N(C)C)OC[C@@H]2CNC[C@@H](O2)n2cc(C)c(=O)[nH]c2=O)n2cnc3c2nc(N)[nH]c3=O)n2cnc3c2ncnc3N)n2ccc(nc2=O)N)n2cnc3c2ncnc3N)n2ccc(nc2=O)N)n2cc(C)c(=O)[nH]c2=O)n2cnc3c2ncnc3N)C[C@@H](O1)n1cnc2c1nc(N)[nH]c2=O)n1cc(C)c(=O)[nH]c1=O)n1ccc(nc1=O)N)n1cc(C)c(=O)[nH]c1=O)n1cc(C)c(=O)[nH]c1=O)n1ccc(nc1=O)N)n1cc(C)c(=O)[nH]c1=O)n1ccc(nc1=O)N)n1cnc2c1nc(N)[nH]c2=O)n1cnc2c1nc(N)[nH]c2=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)Cc1ccccc1)Cc1ccccc1
  • InChi: 1S/C323H520N157O97P21S/c1-185-104-466(318(510)412-275(185)481)232-103-358-102-193(557-232)151-537-580(517,419(9)10)456-127-211(575-249(146-456)477-181-381-258-271(477)403-308(354)408-293(258)499)169-555-595(532,434(39)40)455-126-210(573-248(145-455)475-179-379-256-265(334)371-175-375-269(256)475)167-553-586(523,425(21)22)446-116-200(564-238(135-446)464-94-79-230(329)400-316(464)508)158-544-593(530,432(35)36)453-124-208(571-246(143-453)473-177-377-254-263(332)369-173-373-267(254)473)165-551-585(522,424(19)20)445-115-199(563-237(134-445)463-93-78-229(328)399-315(463)507)157-543-589(526,428(27)28)449-119-203(567-241(138-449)468-106-187(3)277(483)414-320(468)512)160-546-581(518,420(11)12)441-111-195(559-245(142-441)472-176-376-253-262(331)368-172-372-266(253)472)150-536-578-439-110-194(558-233(130-439)476-180-380-257-270(476)402-307(353)407-292(257)498)152-539-588(525,427(25)26)448-118-202(566-240(137-448)467-105-186(2)276(482)413-319(467)511)163-549-594(531,433(37)38)454-125-209(572-247(144-454)474-178-378-255-264(333)370-174-374-268(255)474)166-552-584(521,423(17)18)444-112-196(560-236(133-444)462-92-77-228(327)398-314(462)506)154-540-582(519,421(13)14)442-113-197(561-234(131-442)460-90-75-226(325)396-312(460)504)155-541-590(527,429(29)30)450-121-205(569-242(139-450)469-107-188(4)278(484)415-321(469)513)162-548-592(529,431(33)34)452-120-204(568-244(141-452)471-109-190(6)280(486)417-323(471)515)161-547-583(520,422(15)16)443-114-198(562-235(132-443)461-91-76-227(326)397-313(461)505)156-542-591(528,430(31)32)451-122-206(570-243(140-451)470-108-189(5)279(485)416-322(470)514)164-550-597(534,436(43)44)459-128-212(576-252(149-459)480-184-384-261-274(480)406-311(357)411-296(261)502)168-554-587(524,426(23)24)447-117-201(565-239(136-447)465-95-80-231(330)401-317(465)509)159-545-596(533,435(41)42)458-129-213(577-251(148-458)479-183-383-260-273(479)405-310(356)410-295(260)501)170-556-598(535,437(45)46)457-123-207(574-250(147-457)478-182-382-259-272(478)404-309(355)409-294(259)500)153-538-579(516,418(7)8)440-98-96-438(97-99-440)297(503)225(171-599)395-291(497)224(101-192-64-51-48-52-65-192)394-290(496)223(100-191-62-49-47-50-63-191)393-289(495)222(74-61-89-367-306(351)352)392-288(494)221(73-60-88-366-305(349)350)391-287(493)220(72-59-87-365-304(347)348)390-286(492)219(71-58-86-364-303(345)346)389-285(491)218(70-57-85-363-302(343)344)388-284(490)217(69-56-84-362-301(341)342)387-283(489)216(68-55-83-361-300(339)340)386-282(488)215(67-54-82-360-299(337)338)385-281(487)214(324)66-53-81-359-298(335)336/h47-52,62-65,75-80,90-95,104-109,172-184,193-225,232-252,358,578,599H,53-61,66-74,81-89,96-103,110-171,324H2,1-46H3,(H,385,487)(H,386,488)(H,387,489)(H,388,490)(H,389,491)(H,390,492)(H,391,493)(H,392,494)(H,393,495)(H,394,496)(H,395,497)(H2,325,396,504)(H2,326,397,505)(H2,327,398,506)(H2,328,399,507)(H2,329,400,508)(H2,330,401,509)(H2,331,368,372)(H2,332,369,373)(H2,333,370,374)(H2,334,371,375)(H4,335,336,359)(H4,337,338,360)(H4,339,340,361)(H4,341,342,362)(H4,343,344,363)(H4,345,346,364)(H4,347,348,365)(H4,349,350,366)(H4,351,352,367)(H,412,481,510)(H,413,482,511)(H,414,483,512)(H,415,484,513)(H,416,485,514)(H,417,486,515)(H3,353,402,407,498)(H3,354,403,408,499)(H3,355,404,409,500)(H3,356,405,410,501)(H3,357,406,411,502)/t193-,194-,195-,196-,197-,198-,199-,200-,201-,202-,203-,204-,205-,206-,207-,208-,209-,210-,211-,212-,213-,214-,215-,216-,217-,218-,219-,220-,221-,222-,223-,224-,225-,232+,233+,234+,235+,236+,237+,238+,239+,240+,241+,242+,243+,244+,245+,246+,247+,248+,249+,250+,251+,252+,579?,580?,581?,582?,583?,584?,585?,586?,587?,588?,589?,590?,591?,592?,593?,594?,595?,596?,597?,598?/m0/s1
  • InChiKey: NYLVFCPWVHVYOL-LOPVOAGTSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) leucyl aminopeptidase 0.0022 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0216 0.1524 0.1685
Brugia malayi Animal haem peroxidase family protein 0.0042 0.0186 0.0186
Onchocerca volvulus 0.0042 0.0186 0.0186
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0748 0.5602 0.5602
Loa Loa (eye worm) hypothetical protein 0.0349 0.2542 0.2542
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Onchocerca volvulus Glutaminyl cyclase homolog 0.0022 0.0035 0.0035
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0029 0.0052
Echinococcus multilocularis lamin 0.0026 0.0066 0.0118
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.0029 0.0052
Echinococcus granulosus tyrosine protein kinase otk 0.0022 0.0029 0.0052
Schistosoma mansoni lamin 0.0026 0.0066 0.0073
Loa Loa (eye worm) TK/ROR protein kinase 0.0232 0.164 0.164
Echinococcus granulosus neuroglian 0.0033 0.0119 0.0213
Echinococcus granulosus fibropellin Ia 0.0038 0.0154 0.0275
Onchocerca volvulus 0.0026 0.0066 0.0066
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0748 0.5602 1
Onchocerca volvulus Arrow homolog 0.0041 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Brugia malayi CXXC zinc finger family protein 0.0048 0.0229 0.0229
Echinococcus granulosus carbonic anhydrase 0.0349 0.2542 0.4537
Schistosoma mansoni enhancer of zeste ezh 0.0025 0.0054 0.006
Trypanosoma brucei hypothetical protein, conserved 0.0508 0.3764 0.6719
Trypanosoma brucei glutaminyl cyclase, putative 0.0022 0.0035 0.0063
Echinococcus granulosus protein jagged 2 0.0038 0.0154 0.0275
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.0022 0.0035 0.0063
Toxoplasma gondii calcium binding egf domain-containing protein 0.0041 0.0178 0.0318
Schistosoma mansoni laminin gamma-3 chain 0.0038 0.0154 0.0171
Echinococcus multilocularis neurogenic locus notch protein 4 0.0038 0.0154 0.0275
Schistosoma mansoni septate junction protein 0.0022 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0065 0.0363 0.0363
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0645 0.4809 0.4809
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0047
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0041 0.0178 0.0178
Echinococcus multilocularis neuroglian 0.0033 0.0119 0.0213
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0047
Brugia malayi Calcium binding EGF domain containing protein 0.0038 0.0154 0.0154
Schistosoma mansoni notch 0.0038 0.0154 0.0171
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Leishmania major hypothetical protein, conserved 0.0022 0.0035 0.0063
Echinococcus granulosus notch 0.0038 0.0154 0.0275
Schistosoma mansoni carbonic anhydrase 0.0349 0.2542 0.281
Schistosoma mansoni nicalin (M28 family) 0.0022 0.0035 0.0039
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0591 0.4396 0.4396
Echinococcus multilocularis hemicentin 1 0.0022 0.0029 0.0052
Mycobacterium ulcerans hypothetical protein 0.0087 0.0534 0.0501
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0748 0.5602 0.5602
Onchocerca volvulus Peroxidase homolog 0.0042 0.0186 0.0186
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0087 0.0534 0.0534
Echinococcus multilocularis fibropellin Ia 0.0038 0.0154 0.0275
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0022 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0645 0.4809 0.8584
Trypanosoma brucei Enriched in surface-labeled proteome protein 12 0.0508 0.3764 0.6719
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0748 0.5602 0.5602
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Onchocerca volvulus Neurogenic locus notch homolog 0.0038 0.0154 0.0154
Schistosoma mansoni Fxna peptidase (M28 family) 0.0022 0.0035 0.0039
Echinococcus multilocularis Immunoglobulin 0.0024 0.0047 0.0083
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0041 0.0178 0.0178
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0041 0.0178 0.0178
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0066 0.0066
Onchocerca volvulus 0.0026 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Echinococcus multilocularis carbonic anhydrase 0.0349 0.2542 0.4537
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0508 0.3764 0.6719
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0335 0.2432 0.4341
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Echinococcus multilocularis roundabout 2 0.0045 0.0212 0.0378
Brugia malayi Calcium binding EGF domain containing protein 0.0038 0.0154 0.0154
Echinococcus granulosus enteropeptidase 0.0087 0.0534 0.0954
Brugia malayi Delta serrate ligand family protein 0.0038 0.0154 0.0154
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Echinococcus multilocularis hemicentin 1 0.0022 0.0029 0.0052
Schistosoma mansoni cpg binding protein 0.0049 0.0242 0.0267
Schistosoma mansoni notch 0.0038 0.0154 0.0171
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.0022 0.0035 0.0039
Echinococcus granulosus delta-like protein 1 0.0038 0.0154 0.0275
Brugia malayi Animal haem peroxidase family protein 0.0042 0.0186 0.0186
Schistosoma mansoni notch 0.0038 0.0154 0.0171
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0363 0.0363
Echinococcus multilocularis casein kinase ii subunit alpha 0.0065 0.0363 0.0649
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0036 0.0139 0.0248
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0748 0.5602 0.5602
Plasmodium falciparum cysteine repeat modular protein 1 0.0216 0.1524 0.2721
Echinococcus granulosus lamin 0.0026 0.0066 0.0118
Brugia malayi Kringle domain containing protein 0.0216 0.1524 0.1524
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Echinococcus multilocularis lachesin 0.0022 0.0029 0.0052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Loa Loa (eye worm) animal heme peroxidase 0.0042 0.0186 0.0186
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Echinococcus granulosus neurogenic locus notch protein 0.0038 0.0154 0.0275
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0087 0.0534 0.0954
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0047 0.0047
Echinococcus granulosus transmembrane protease serine 3 0.0087 0.0534 0.0954
Loa Loa (eye worm) animal heme peroxidase 0.0042 0.0186 0.0186
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0087 0.0534 0.0591
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0274 0.049
Onchocerca volvulus 0.0022 0.0035 0.0035
Echinococcus multilocularis carbonic anhydrase 0.0349 0.2542 0.4537
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0349 0.2542 0.2542
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0029
Echinococcus granulosus hemicentin 1 0.0022 0.0029 0.0052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Mycobacterium tuberculosis Probable enoyl-CoA hydratase EchA14 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) 0.03 0.2162 0.2135
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0022 0.0035 0.0039
Loa Loa (eye worm) trypsin family protein 0.0087 0.0534 0.0534
Schistosoma mansoni carbonic anhydrase-related 0.0349 0.2542 0.281
Loa Loa (eye worm) blistered cuticle protein 3 0.0042 0.0186 0.0186
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0216 0.1524 0.2721
Echinococcus multilocularis lamin dm0 0.0026 0.0066 0.0118
Brugia malayi EGF-like domain containing protein 0.0038 0.0154 0.0154
Echinococcus multilocularis roundabout 2 0.0022 0.0029 0.0052
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0038 0.0154 0.0171
Schistosoma mansoni nephrin 0.0033 0.0119 0.0132
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0363 0.0363
Schistosoma mansoni tyrosine kinase 0.0027 0.0072 0.008
Echinococcus granulosus neurogenic locus notch protein 0.0038 0.0154 0.0275
Echinococcus multilocularis fibrillin 1 0.0041 0.0178 0.0318
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0087 0.0534 0.0954
Echinococcus granulosus roundabout 2 0.0022 0.0029 0.0052
Brugia malayi Animal haem peroxidase family protein 0.0042 0.0186 0.0186
Trypanosoma brucei carbonic anhydrase-like protein 0.0645 0.4809 0.8584
Loa Loa (eye worm) hypothetical protein 0.0641 0.478 0.478
Schistosoma mansoni microtubule-associated protein 0.0045 0.0211 0.0233
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0212
Brugia malayi intermediate filament protein 0.0026 0.0066 0.0066
Onchocerca volvulus 0.0038 0.0154 0.0154
Onchocerca volvulus 0.0038 0.0154 0.0154
Trypanosoma brucei Casein kinase II 0.0065 0.0363 0.0649
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0022 0.0029 0.0052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0065 0.0361 0.0361
Brugia malayi Trypsin family protein 0.0087 0.0534 0.0534
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0349 0.2542 0.2542
Onchocerca volvulus 0.0038 0.0154 0.0154
Onchocerca volvulus Chorion peroxidase homolog 0.0042 0.0186 0.0186
Echinococcus granulosus roundabout 2 0.0022 0.0029 0.0052
Brugia malayi hypothetical protein 0.0024 0.0047 0.0047
Schistosoma mansoni cell adhesion molecule 0.0036 0.0139 0.0154
Echinococcus granulosus protein jagged 1 0.0038 0.0154 0.0275
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Entamoeba histolytica protein kinase domain containing protein 0.0065 0.0363 0.0363
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0508 0.3764 0.6719
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0748 0.5602 0.5602
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0748 0.5602 1
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0748 0.5602 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0349 0.2542 0.2542
Echinococcus multilocularis laminin 0.0041 0.0178 0.0318
Loa Loa (eye worm) notch protein 0.0038 0.0154 0.0154
Schistosoma mansoni protein kinase 0.0065 0.0363 0.0402
Schistosoma mansoni carbonic anhydrase-related 0.0349 0.2542 0.281
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0066 0.0066
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0022 0.0029 0.0029
Echinococcus granulosus Mastin 0.0087 0.0534 0.0954
Echinococcus multilocularis neural cadherin 0.0038 0.0154 0.0275
Brugia malayi Peroxidasin 0.0064 0.0351 0.0351
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0748 0.5602 1
Brugia malayi EGF-like domain containing protein 0.0038 0.0154 0.0154
Onchocerca volvulus 0.0549 0.4077 0.4077
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0022 0.0035 0.0063
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.003 0.0098 0.0063
Brugia malayi Calcium binding EGF domain containing protein 0.0038 0.0154 0.0154
Brugia malayi Cadherin domain containing protein 0.0038 0.0154 0.0154
Echinococcus multilocularis fat cadherin tumor suppressor 0.0038 0.0154 0.0275
Toxoplasma gondii calcium binding egf domain-containing protein 0.0041 0.0178 0.0318
Echinococcus multilocularis enteropeptidase 0.0087 0.0534 0.0954
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.1524 0.2721
Echinococcus multilocularis carbonic anhydrase 0.0349 0.2542 0.4537
Giardia lamblia High cysteine protein 0.0038 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0038 0.0154 0.0171
Plasmodium falciparum carbonic anhydrase 0.0349 0.2542 0.4537
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Toxoplasma gondii hypothetical protein 0.0022 0.0035 0.0063
Loa Loa (eye worm) hypothetical protein 0.0087 0.0534 0.0534
Echinococcus multilocularis Tolloid protein 1 0.0041 0.0178 0.0318
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0024 0.0047 0.0083
Echinococcus multilocularis transmembrane protease serine 3 0.0087 0.0534 0.0954
Echinococcus granulosus casein kinase ii subunit alpha 0.0065 0.0363 0.0649
Onchocerca volvulus 0.0087 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0041 0.0178 0.0178
Brugia malayi jmjC domain containing protein 0.0024 0.0047 0.0047
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0066 0.0066
Echinococcus granulosus protein jagged 2 0.0038 0.0154 0.0275
Brugia malayi Peptidase family M28 containing protein 0.0022 0.0035 0.0035
Schistosoma mansoni notch 0.0038 0.0154 0.0171
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0038 0.0154 0.0154
Onchocerca volvulus Tyrosine kinase homolog 0.0564 0.4193 0.4193
Echinococcus granulosus cpg binding protein 0.0049 0.0242 0.0431
Plasmodium vivax unspecified product 0.0065 0.0363 0.0649
Echinococcus granulosus slit 2 protein 0.0038 0.0154 0.0275
Brugia malayi Fibulin-1 precursor 0.0041 0.0178 0.0178
Brugia malayi Immunoglobulin I-set domain containing protein 0.0591 0.4396 0.4396
Echinococcus granulosus twitchin 0.0034 0.0123 0.0219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0041 0.0178 0.0178
Echinococcus granulosus neural cadherin 0.0038 0.0154 0.0275
Echinococcus multilocularis Mastin 0.0087 0.0534 0.0954
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0047
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0087 0.0534 0.0591
Schistosoma mansoni notch 0.0038 0.0154 0.0171
Leishmania major glutaminyl cyclase, putative 0.0022 0.0035 0.0063
Schistosoma mansoni hypothetical protein 0.0087 0.0534 0.0591
Loa Loa (eye worm) hypothetical protein 0.0041 0.0178 0.0178
Trypanosoma brucei hypothetical protein, conserved 0.0508 0.3764 0.6719
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0065 0.0363 0.0649
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0363 0.0363
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0508 0.3764 0.6719
Brugia malayi Animal haem peroxidase family protein 0.0042 0.0186 0.0186
Brugia malayi EGF-like domain containing protein 0.0038 0.0154 0.0154
Schistosoma mansoni vesicular amine transporter 0.0024 0.0047 0.0051
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0748 0.5602 0.5602
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0029
Echinococcus multilocularis roundabout 2 0.0022 0.0029 0.0052
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0645 0.4809 0.4809
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0029
Toxoplasma gondii hypothetical protein 0.0349 0.2542 0.4537
Echinococcus multilocularis neurogenic locus notch protein 0.0038 0.0154 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Trypanosoma cruzi glutaminyl cyclase, putative 0.0022 0.0035 0.0063
Leishmania major hypothetical protein, conserved 0.0216 0.1524 0.2721
Toxoplasma gondii CMGC kinase, CK2 family 0.0065 0.0363 0.0649
Loa Loa (eye worm) animal heme peroxidase 0.0042 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0047
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0087 0.0534 0.0954
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0087 0.0534 0.0591
Schistosoma mansoni cpg binding protein 0.0049 0.0242 0.0267
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0022 0.0035 0.0063
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0748 0.5602 0.5602
Echinococcus granulosus histone lysine N methyltransferase Ez 0.0025 0.0054 0.0097
Brugia malayi Calcium binding EGF domain containing protein 0.0041 0.0178 0.0178
Loa Loa (eye worm) SET domain-containing protein 0.0025 0.0054 0.0054
Plasmodium falciparum casein kinase 2, alpha subunit 0.0065 0.0363 0.0649
Schistosoma mansoni cell adhesion molecule 0.0022 0.0029 0.0032
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0022 0.0029 0.0052
Brugia malayi hypothetical protein 0.0042 0.0186 0.0186
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0508 0.3764 0.6719
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Brugia malayi notch-like transmembrane receptor 0.0038 0.0154 0.0154
Schistosoma mansoni cell polarity protein 0.0038 0.0154 0.0171
Schistosoma mansoni intermediate filament proteins 0.0026 0.0066 0.0073
Echinococcus granulosus dnaJ subfamily B 0.04 0.2928 0.5227
Onchocerca volvulus Peroxidase homolog 0.0042 0.0186 0.0186
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.003 0.0098 0.0063
Loa Loa (eye worm) carbonic anhydrase 3 0.0645 0.4809 0.4809
Echinococcus multilocularis protein jagged 1 0.0038 0.0154 0.0275
Trypanosoma cruzi casein kinase II, putative 0.0065 0.0363 0.0649
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0748 0.5602 1
Echinococcus granulosus carbonic anhydrase 0.0349 0.2542 0.4537
Loa Loa (eye worm) CXXC zinc finger family protein 0.0048 0.0229 0.0229
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0029 0.0052
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Brugia malayi jmjC domain containing protein 0.0024 0.0047 0.0047
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0349 0.2542 0.2542
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0363 0.0363
Onchocerca volvulus Fxna peptidase homolog 0.0022 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Schistosoma mansoni slit 0.0038 0.0154 0.0171
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0218 0.1533 0.1695
Schistosoma mansoni hypothetical protein 0.0038 0.0154 0.0171
Echinococcus multilocularis histone lysine N methyltransferase E(z) 0.0025 0.0054 0.0097
Loa Loa (eye worm) hypothetical protein 0.0216 0.1524 0.1524
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0041 0.0178 0.0197
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0748 0.5602 0.6194
Onchocerca volvulus 0.0042 0.0186 0.0186
Schistosoma mansoni roundabout 0.0022 0.0029 0.0032
Schistosoma mansoni septate junction protein 0.0022 0.0029 0.0032
Schistosoma mansoni hypothetical protein 0.0349 0.2542 0.281
Brugia malayi SET domain containing protein 0.0025 0.0054 0.0054
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0508 0.3764 0.6719
Onchocerca volvulus Slit protein homolog 0.0038 0.0154 0.0154
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0087 0.0534 0.0591
Echinococcus granulosus tissue type plasminogen activator 0.0216 0.1524 0.2721
Echinococcus granulosus neurogenic locus notch protein 4 0.0038 0.0154 0.0275
Onchocerca volvulus Putative cubilin 0.0038 0.0154 0.0154
Toxoplasma gondii peptidase, M28 family protein 0.0022 0.0035 0.0063
Schistosoma mansoni hypothetical protein 0.04 0.2928 0.3238
Echinococcus granulosus protein jagged 1 0.0038 0.0154 0.0275
Echinococcus multilocularis neuroglian 0.0022 0.0029 0.0052
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0645 0.4809 0.5317
Echinococcus granulosus Immunoglobulin 0.0024 0.0047 0.0083
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0038 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0062
Echinococcus multilocularis peroxidasin 0.0064 0.0351 0.0627
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0035 0.0035
Schistosoma mansoni titin 0.0022 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0349 0.2542 0.2542
Brugia malayi GCC2 and GCC3 family protein 0.0038 0.0154 0.0154
Brugia malayi Muscle positioning protein 4 0.0038 0.0154 0.0154
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0024 0.0047 0.0051
Leishmania major casein kinase II, putative 0.0065 0.0363 0.0649
Loa Loa (eye worm) hypothetical protein 0.0312 0.2261 0.2261
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0072 0.0418 0.0462
Echinococcus multilocularis Immunoglobulin 0.0024 0.0047 0.0083
Brugia malayi Animal haem peroxidase family protein 0.0051 0.0258 0.0258
Echinococcus multilocularis tyrosine protein kinase otk 0.0022 0.0029 0.0052
Echinococcus multilocularis neurogenic locus protein delta 0.0038 0.0154 0.0275
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.0022 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Toxoplasma gondii kringle domain-containing protein 0.0216 0.1524 0.2721
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0087 0.0534 0.0591
Schistosoma mansoni notch 0.0038 0.0154 0.0171
Onchocerca volvulus Fxna peptidase homolog 0.0022 0.0035 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0363 0.0363
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Trypanosoma cruzi glutaminyl cyclase, putative 0.0022 0.0035 0.0063
Loa Loa (eye worm) hypothetical protein 0.0641 0.478 0.478
Brugia malayi Trypsin family protein 0.0087 0.0534 0.0534
Echinococcus multilocularis neurogenic locus protein delta 0.0038 0.0154 0.0275
Schistosoma mansoni lamin 0.0026 0.0066 0.0073
Onchocerca volvulus 0.0554 0.4109 0.4109
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0087 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Echinococcus multilocularis dnaJ subfamily B 0.04 0.2928 0.5227
Echinococcus granulosus glycoprotein Antigen 5 0.0087 0.0534 0.0954
Echinococcus granulosus roundabout 2 0.0045 0.0212 0.0378
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0349 0.2542 0.2542
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0748 0.5602 1
Onchocerca volvulus 0.0042 0.0186 0.0186
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0024 0.0047 0.0051
Echinococcus granulosus neurogenic locus protein delta 0.0038 0.0154 0.0275
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0038 0.0154 0.0171
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0748 0.5602 1
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0748 0.5602 1
Brugia malayi leucyl aminopeptidase 0.0022 0.0035 0.0035
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0645 0.4809 0.4809
Echinococcus multilocularis microtubule associated protein 1A 0.0045 0.0211 0.0376
Loa Loa (eye worm) hypothetical protein 0.0343 0.2494 0.2494
Entamoeba histolytica casein kinase, putative 0.0065 0.0363 0.0363
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0029 0.0052
Brugia malayi FXNA 0.0022 0.0035 0.0035
Schistosoma mansoni cell adhesion molecule 0.0022 0.0029 0.0032
Giardia lamblia Kinase, CMGC CK2 0.0065 0.0363 0.0363
Schistosoma mansoni peroxidasin 0.0042 0.0186 0.0206
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0645 0.4809 0.8584
Onchocerca volvulus 0.0038 0.0154 0.0154
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0029 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0363 0.0363
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0363 0.0363
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Echinococcus multilocularis protein jagged 2 0.0038 0.0154 0.0275
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0029
Echinococcus granulosus neuroglian 0.0022 0.0029 0.0052
Schistosoma mansoni hypothetical protein 0.0038 0.0154 0.0171
Echinococcus multilocularis tissue type plasminogen activator 0.0216 0.1524 0.2721
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0087 0.0534 0.0954
Brugia malayi Trypsin family protein 0.0087 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0087 0.0534 0.0534
Schistosoma mansoni septate junction protein 0.0038 0.0154 0.0171
Leishmania major carbonic anhydrase-like protein 0.0645 0.4809 0.8584
Brugia malayi EGF-like domain containing protein 0.0038 0.0154 0.0154
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0219 0.1547 0.171
Echinococcus multilocularis neurogenic locus notch protein 0.0038 0.0154 0.0275
Loa Loa (eye worm) hypothetical protein 0.0349 0.2542 0.2542
Brugia malayi Protein kinase domain containing protein 0.0222 0.1567 0.1567
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Onchocerca volvulus 0.0087 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0036 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Brugia malayi EGF-like domain containing protein 0.0038 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0228 0.1609 0.1609
Onchocerca volvulus Fxna peptidase homolog 0.0022 0.0035 0.0035
Schistosoma mansoni egf-like domain protein 0.0041 0.0178 0.0197
Echinococcus multilocularis glycoprotein Antigen 5 0.0087 0.0534 0.0954
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0087 0.0534 0.0534
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0641 0.478 0.5285
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0641 0.478 0.5285
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0748 0.5602 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0323 0.0357
Loa Loa (eye worm) hypothetical protein 0.0087 0.0534 0.0534
Brugia malayi EGF-like domain containing protein 0.0038 0.0154 0.0154
Echinococcus granulosus peroxidasin 0.0064 0.0351 0.0627
Echinococcus multilocularis musashi 0.0026 0.0066 0.0118
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0349 0.2542 0.2542
Onchocerca volvulus Peroxidasin homolog 0.0051 0.0258 0.0258
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0029 0.0032
Onchocerca volvulus 0.0216 0.1524 0.1524
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0029 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.0022 0.0035 0.0063
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.0258 0.0258
Brugia malayi Fibronectin type III domain containing protein 0.0024 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Onchocerca volvulus Peroxidasin homolog 0.0051 0.0258 0.0258
Brugia malayi Casein kinase II, alpha chain 0.0065 0.0363 0.0363
Echinococcus granulosus microtubule associated protein 1A 0.0045 0.0211 0.0376
Schistosoma mansoni peroxidasin 0.0054 0.0278 0.0308
Brugia malayi Trypsin family protein 0.0641 0.478 0.478
Schistosoma mansoni neuroglian 0.0022 0.0029 0.0032
Onchocerca volvulus 0.0087 0.0534 0.0534
Echinococcus granulosus carbonic anhydrase II 0.0645 0.4809 0.8584
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Schistosoma mansoni cpg binding protein 0.0048 0.0229 0.0254
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0047
Brugia malayi nicalin 0.0022 0.0035 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0029 0.0029
Echinococcus multilocularis cpg binding protein 0.0049 0.0242 0.0431
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0035
Onchocerca volvulus 0.0038 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0042 0.0186 0.0186
Toxoplasma gondii EGF family domain-containing protein 0.0038 0.0154 0.0275
Schistosoma mansoni carbonic anhydrase-related 0.0349 0.2542 0.281
Echinococcus granulosus defective proboscis extension response 0.0024 0.0047 0.0083
Echinococcus granulosus carbonic anhydrase 0.0349 0.2542 0.4537
Echinococcus granulosus intermediate filament protein 0.0026 0.0066 0.0118
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Brugia malayi hypothetical protein 0.0087 0.0534 0.0534
Schistosoma mansoni hypothetical protein 0.0038 0.0154 0.0171
Loa Loa (eye worm) hypothetical protein 0.0064 0.0351 0.0351
Brugia malayi Prion-like- 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Onchocerca volvulus 0.0087 0.0534 0.0534
Brugia malayi Cadherin domain containing protein 0.0038 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0038 0.0154 0.0154
Onchocerca volvulus Dual oxidase homolog 0.0042 0.0186 0.0186
Echinococcus granulosus laminin 0.0041 0.0178 0.0318
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0645 0.4809 0.5317
Schistosoma mansoni microtubule-associated protein 0.0045 0.0211 0.0233
Echinococcus multilocularis notch 0.0038 0.0154 0.0275
Schistosoma mansoni cell adhesion molecule 0.0022 0.0029 0.0032
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0022 0.0035 0.0063
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0029
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0022 0.0035 0.0063
Echinococcus granulosus lachesin 0.0022 0.0029 0.0052
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Onchocerca volvulus 0.0641 0.478 0.478
Schistosoma mansoni hypothetical protein 0.0087 0.0534 0.0591
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Loa Loa (eye worm) hypothetical protein 0.0041 0.0178 0.0178
Schistosoma mansoni hypothetical protein 0.0038 0.0154 0.0171
Echinococcus multilocularis carbonic anhydrase II 0.0645 0.4809 0.8584
Echinococcus granulosus lamin dm0 0.0026 0.0066 0.0118
Schistosoma mansoni nephrin 0.0022 0.0029 0.0032
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0087 0.0534 0.0591
Brugia malayi Blistered cuticle protein 3 0.0042 0.0186 0.0186
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1197 0.9044 1
Loa Loa (eye worm) Notch2 0.0038 0.0154 0.0154
Echinococcus granulosus Tolloid protein 1 0.0041 0.0178 0.0318
Brugia malayi EGF-like domain containing protein 0.0038 0.0154 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0035 0.0035
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0041 0.0178 0.0178
Echinococcus multilocularis protein jagged 1 0.0038 0.0154 0.0275
Schistosoma mansoni cercarial elastase (S01 family) 0.0087 0.0534 0.0591
Echinococcus multilocularis slit 2 protein 0.0038 0.0154 0.0275
Brugia malayi Trypsin-like protease protein 5 0.0087 0.0534 0.0534
Echinococcus granulosus contactin 0.0022 0.0029 0.0052
Onchocerca volvulus 0.0048 0.0229 0.0229
Schistosoma mansoni hypothetical protein 0.0038 0.0154 0.0171
Onchocerca volvulus 0.0087 0.0534 0.0534

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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