Detailed information for compound 1515208

Basic information

Technical information
  • TDR Targets ID: 1515208
  • Name: (2S)-3-(3-aminophenyl)sulfanyl-N-[4-cyano-3-( trifluoromethyl)phenyl]-2-hydroxy-2-methylpro panamide
  • MW: 395.399 | Formula: C18H16F3N3O2S
  • H donors: 3 H acceptors: 3 LogP: 2.8 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccc(cc1C(F)(F)F)NC(=O)[C@@](CSc1cccc(c1)N)(O)C
  • InChi: 1S/C18H16F3N3O2S/c1-17(26,10-27-14-4-2-3-12(23)7-14)16(25)24-13-6-5-11(9-22)15(8-13)18(19,20)21/h2-8,26H,10,23H2,1H3,(H,24,25)/t17-/m1/s1
  • InChiKey: QNFYWRWLVYZGOG-QGZVFWFLSA-N  

Network

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Synonyms

  • (2S)-3-(3-aminophenyl)sulfanyl-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-propanamide
  • (2S)-3-[(3-aminophenyl)thio]-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
  • (2S)-3-[(3-aminophenyl)thio]-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-propionamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Androgen Receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0231 0.0555 0.0519
Onchocerca volvulus 0.0487 0.1572 0.535
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Schistosoma mansoni tyrosine kinase 0.0587 0.1969 0.1969
Plasmodium falciparum protein kinase 5 0.0242 0.0602 0.0554
Entamoeba histolytica p21-activated kinase 0.0191 0.0398 0.1112
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0335 0.0968 0.0934
Schistosoma mansoni nephrin related 0.0128 0.0148 0.0148
Echinococcus multilocularis expressed conserved protein 0.0172 0.0323 0.0286
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0539 0.1778 0.1747
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Trypanosoma brucei polo-like protein kinase 0.0551 0.1827 0.1785
Onchocerca volvulus 0.0183 0.0367 0.1249
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0904 0.3229 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0174 0.0328 0.0328
Onchocerca volvulus 0.0487 0.1572 0.535
Brugia malayi Pleckstrin Homology Domain 0.0101 0.0038 0.0038
Toxoplasma gondii rhoptry neck protein RON1 0.0487 0.1572 0.1528
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0112 0.0083 0.0083
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0904 0.3229 0.3194
Echinococcus granulosus down syndrome cell adhesion 0.0128 0.0148 0.0111
Echinococcus granulosus protein kinase c iota type 0.0582 0.1952 0.1921
Loa Loa (eye worm) hypothetical protein 0.0541 0.1789 0.1789
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0749 0.0749
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.0491 0.0491
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0128 0.0148 0.0111
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.016 0.0274 0.0224
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0904 0.3229 0.3203
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0765 0.2246
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0664 0.2276 0.2276
Leishmania major protein kinase A catalytic subunit 0.0231 0.0555 0.0507
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0307 0.0857 0.0822
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.0823 0.0823
Echinococcus multilocularis epidermal growth factor receptor 0.0492 0.1595 0.1563
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0904 0.3229 0.3194
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0083 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0555 0.0555
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0523 0.1718 0.1718
Brugia malayi Myb-like DNA-binding domain containing protein 0.0128 0.0148 0.0148
Schistosoma mansoni protein kinase 0.0132 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0472 0.1515 0.1515
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0173 0.0326 0.0881
Onchocerca volvulus 0.0128 0.0148 0.0505
Schistosoma mansoni tyrosine kinase 0.0311 0.0875 0.0875
Echinococcus granulosus glutamate synthase 0.024 0.0591 0.0556
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0765 0.2246
Echinococcus multilocularis serine:threonine protein kinase 0.0233 0.0564 0.0528
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.024 0.0591 0.1694
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0222 0.052 0.052
Echinococcus granulosus C type lectin domian containing protein 0.0487 0.1572 0.1539
Echinococcus granulosus protein tyrosine kinase 0.0587 0.1969 0.1939
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0658 0.2255 0.2225
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0206 0.0456 0.042
Echinococcus granulosus c4b binding protein beta chain 0.0487 0.1572 0.1539
Echinococcus multilocularis 0.0128 0.0148 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.05 0.1623 0.1623
Loa Loa (eye worm) hypothetical protein 0.0279 0.0749 0.0749
Echinococcus granulosus tm gpcr rhodopsin 0.0287 0.078 0.0745
Schistosoma mansoni growth factor receptor-bound protein 0.0127 0.0143 0.0143
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0152 0.0244 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0592 0.1992 0.1992
Loa Loa (eye worm) hypothetical protein 0.0166 0.0297 0.0297
Schistosoma mansoni tyrosine kinase 0.0311 0.0875 0.0875
Brugia malayi Fes/CIP4 homology domain containing protein 0.0208 0.0466 0.0466
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.024 0.0591 0.0543
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0128 0.0148 0.0111
Brugia malayi Immunoglobulin domain containing protein 0.0151 0.0239 0.0239
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0104 0.0051 0.0027
Echinococcus granulosus tyrosine protein kinase Src42A 0.0311 0.0875 0.084
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.024 0.0591 0.0543
Echinococcus granulosus protein kinase c epsilon type 0.0416 0.1292 0.1258
Loa Loa (eye worm) hypothetical protein 0.0371 0.1113 0.1113
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0456 0.0456
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.017 0.0313 0.0263
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0416 0.1292 0.1292
Echinococcus granulosus tyrosine kinase 0.0253 0.0645 0.061
Onchocerca volvulus 0.0215 0.0491 0.1672
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0204 0.0451 0.0451
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0803 0.2829 0.2829
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0231 0.0555 0.0507
Plasmodium falciparum NIMA related kinase 1 0.0278 0.0742 0.0695
Echinococcus multilocularis Immunoglobulin 0.0507 0.1654 0.1622
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Echinococcus multilocularis epidermal growth factor receptor 0.0706 0.2446 0.2417
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Schistosoma mansoni titin 0.0128 0.0148 0.0148
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0295 0.0811 0.0776
Schistosoma mansoni hypothetical protein 0.0128 0.0148 0.0148
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0718 0.2493 0.2493
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0876 0.3119 0.3093
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0151 0.0239 0.0239
Leishmania major protein kinase, putative 0.024 0.0592 0.0544
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0206 0.0456 0.0408
Trichomonas vaginalis glutamate synthase, putative 0.024 0.0591 0.1701
Loa Loa (eye worm) hypothetical protein 0.0151 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0678 0.2333 0.2333
Echinococcus multilocularis c src tyrosine kinase 0.0191 0.0398 0.0362
Echinococcus granulosus tyrosine protein kinase Fyn 0.0311 0.0875 0.084
Plasmodium falciparum protein kinase, putative 0.0134 0.0171 0.012
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0253 0.0645 0.061
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0239 0.0239
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.0318 0.084
Trypanosoma cruzi aurora B kinase, putative 0.024 0.0592 0.0544
Schistosoma mansoni tyrosine kinase 0.0346 0.1012 0.1012
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1918 0.726 0.726
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0231 0.0555 0.0519
Echinococcus granulosus contactin 0.0298 0.0823 0.0788
Trypanosoma cruzi Protein kinase B 0.0335 0.0969 0.0923
Schistosoma mansoni titin 0.0147 0.0222 0.0222
Brugia malayi Protein kinase domain containing protein 0.0442 0.1396 0.1396
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.024 0.0591 0.0543
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0749 0.0749
Echinococcus multilocularis hemicentin 1 0.0279 0.0749 0.0714
Loa Loa (eye worm) hypothetical protein 0.0227 0.0542 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0367 0.0994
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0884 0.3151 0.3125
Echinococcus granulosus insulin receptor 0.0612 0.2069 0.2039
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0206 0.0456 0.042
Echinococcus multilocularis mitogen activated protein kinase 11 0.0325 0.0928 0.0893
Schistosoma mansoni sulfide quinone reductase 0.024 0.0591 0.0591
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0283 0.0765 0.0718
Echinococcus multilocularis Immunoglobulin subtype 0.0151 0.0239 0.0202
Entamoeba histolytica PH domain containing protein kinase, putative 0.0246 0.0616 0.1813
Brugia malayi Egg laying defective protein 4 0.0172 0.0323 0.0323
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.024 0.0591 0.0543
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.0943 0.0943
Schistosoma mansoni disulfide oxidoreductase 0.024 0.0591 0.0591
Brugia malayi casein kinase 1, delta 0.0222 0.052 0.052
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0884 0.3151 0.3125
Schistosoma mansoni notch 0.0293 0.0802 0.0802
Loa Loa (eye worm) hypothetical protein 0.0507 0.1654 0.1654
Onchocerca volvulus 0.0128 0.0148 0.0505
Echinococcus granulosus casein kinase I delta 0.0222 0.052 0.0484
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0479 0.1542 0.1509
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0313 0.0884 0.0837
Entamoeba histolytica protein kinase, putative 0.0107 0.0062 0.0036
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0311 0.0875 0.084
Entamoeba histolytica casein kinase 1, putative 0.0222 0.052 0.1503
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0242 0.0602 0.0602
Brugia malayi p70 ribosomal S6 kinase beta 0.058 0.1943 0.1943
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Echinococcus granulosus dual specificity 0.0283 0.0765 0.073
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0413 0.128 0.1246
Trichomonas vaginalis disulfide oxidoreductase, putative 0.024 0.0591 0.1701
Echinococcus granulosus casein kinase I gamma 0.0435 0.1366 0.1333
Echinococcus granulosus N chimaerin 0.0152 0.0244 0.0207
Schistosoma mansoni serine/threonine kinase 0.0459 0.1463 0.1463
Echinococcus granulosus Vam6:Vps39 protein 0.0227 0.0542 0.0506
Entamoeba histolytica protein kinase, putative 0.0206 0.0456 0.13
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.024 0.0592 0.1736
Schistosoma mansoni cell adhesion molecule 0.0147 0.0222 0.0222
Schistosoma mansoni ephrin receptor 0.0197 0.0419 0.0419
Trichomonas vaginalis disulfide oxidoreductase, putative 0.024 0.0591 0.1701
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0112 0.0083 0.01
Echinococcus multilocularis dual specificity testis specific protein kinase 0.045 0.1428 0.1396
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0204 0.0451 0.0428
Leishmania major protein kinase A catalytic subunit isoform 1 0.0231 0.0555 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0479 0.1542 0.1542
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0279 0.0749 0.0714
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0155 0.0256 0.0219
Echinococcus granulosus cyclin dependent kinase 9 0.0181 0.0359 0.0322
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0222 0.0222
Brugia malayi probable protein kinase 0.054 0.1783 0.1783
Echinococcus granulosus serine:threonine protein kinase 0.0233 0.0564 0.0528
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.024 0.0591 0.0543
Giardia lamblia Glutamate synthase 0.024 0.0591 0.1701
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0152 0.0244 0.0207
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0228 0.0544 0.0544
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0732 0.0732
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0171 0.0318 0.0268
Schistosoma mansoni titin 0.0215 0.0491 0.0491
Echinococcus granulosus neuroglian 0.0636 0.2164 0.2134
Loa Loa (eye worm) hypothetical protein 0.0487 0.1572 0.1572
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0231 0.0555 0.0507
Brugia malayi follicle stimulating hormone receptor 0.0181 0.0358 0.0358
Plasmodium vivax serine/threonine protein kinase, putative 0.017 0.0313 0.029
Echinococcus granulosus ephrin type A receptor 4 A 0.0197 0.0419 0.0383
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Echinococcus granulosus tyrosine protein kinase otk 0.0279 0.0749 0.0714
Loa Loa (eye worm) hypothetical protein 0.0298 0.0823 0.0823
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.024 0.0592 0.1736
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0311 0.0875 0.084
Trichomonas vaginalis CMGC family protein kinase 0.0313 0.0884 0.262
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Plasmodium falciparum cGMP-dependent protein kinase 0.0172 0.0323 0.0273
Echinococcus multilocularis neurogenic locus notch protein 0.0293 0.0802 0.0767
Echinococcus granulosus defective proboscis extension response 0.0507 0.1654 0.1622
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0148 0.0148
Giardia lamblia Kinase, CAMK CAMKL 0.0177 0.0341 0.0912
Giardia lamblia Kinase, CAMK CAMKL 0.0177 0.0341 0.0912
Giardia lamblia Kinase, CK1 Casein kinase 0.0222 0.052 0.1475
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0051 0.0051
Leishmania major NADH dehydrogenase, putative 0.024 0.0591 0.0543
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.05 0.1623 0.1591
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0295 0.0812 0.0777
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0884 0.0884
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0177 0.0341 0.0318
Echinococcus multilocularis titin 0.0128 0.0148 0.0111
Echinococcus multilocularis serine:threonine protein kinase N2 0.0328 0.0943 0.0908
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0062 0.0062
Schistosoma mansoni notch 0.0293 0.0802 0.0802
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0128 0.0148 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0968 0.0968
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0227 0.0542 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0765 0.2246
Leishmania major hypothetical protein, conserved 0.024 0.0591 0.0543
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0206 0.0456 0.0408
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.017 0.0313 0.0263
Onchocerca volvulus Tyrosine kinase homolog 0.083 0.2937 1
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0166 0.03 0.0263
Trichomonas vaginalis AGC family protein kinase 0.0596 0.2005 0.6148
Echinococcus granulosus tyrosine kinase 0.0133 0.0169 0.0131
Brugia malayi cyclin-dependent kinase 9 0.0164 0.0291 0.0291
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0904 0.3229 0.3203
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0263 0.0682 0.0646
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.024 0.0591 0.0543
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0904 0.3229 1
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0313 0.0884 0.0837
Echinococcus multilocularis aurora kinase A 0.024 0.0592 0.0556
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.03 0.03
Schistosoma mansoni septate junction protein 0.0293 0.0802 0.0802
Plasmodium falciparum serine/threonine protein kinase KIN 0.016 0.0274 0.0224
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0227 0.0542 0.0494
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0112 0.0083 0.0032
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0442 0.1396 0.1396
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0313 0.0884 0.0837
Schistosoma mansoni nephrin 0.0654 0.2238 0.2238
Mycobacterium ulcerans NADH dehydrogenase 0.024 0.0591 0.1694
Entamoeba histolytica protein kinase domain containing protein 0.0283 0.0765 0.229
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0473 0.1518 0.1518
Schistosoma mansoni notch 0.0293 0.0802 0.0802
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Echinococcus multilocularis ephrin type A receptor 4 A 0.0197 0.0419 0.0383
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0339 0.0984 0.0984
Schistosoma mansoni tyrosine kinase 0.041 0.1267 0.1267
Schistosoma mansoni hypothetical protein 0.0151 0.0239 0.0239
Schistosoma mansoni hypothetical protein 0.0293 0.0802 0.0802
Trichomonas vaginalis CAMK family protein kinase 0.0206 0.0456 0.1276
Trypanosoma brucei cdc2-related kinase 1 0.0242 0.0602 0.0554
Trichomonas vaginalis CK1 family protein kinase 0.0222 0.052 0.1475
Echinococcus multilocularis CDC7 cell division cycle 7 0.0183 0.0367 0.033
Echinococcus multilocularis serine threonine protein kinase 0.0412 0.1274 0.1241
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Echinococcus granulosus titin 0.0215 0.0491 0.0455
Schistosoma mansoni hypothetical protein 0.0293 0.0802 0.0802
Schistosoma mansoni septate junction protein 0.0279 0.0749 0.0749
Schistosoma mansoni hypothetical protein 0.0293 0.0802 0.0802
Brugia malayi Protein kinase domain containing protein 0.1176 0.431 0.431
Entamoeba histolytica protein kinase, putative 0.017 0.0313 0.084
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.069 0.2379 0.2379
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Entamoeba histolytica protein kinase domain containing protein 0.0263 0.0682 0.2022
Echinococcus granulosus serine:threonine protein kinase 12 B 0.024 0.0592 0.0556
Schistosoma mansoni cell adhesion molecule 0.0279 0.0749 0.0749
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.024 0.0591 0.0543
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0181 0.0358 0.0358
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0904 0.3229 0.3194
Schistosoma mansoni tyrosine kinase 0.0353 0.1041 0.1041
Schistosoma mansoni serine/threonine protein kinase 0.0435 0.1366 0.1366
Loa Loa (eye worm) hypothetical protein 0.0338 0.0982 0.0982
Leishmania major hypothetical protein, conserved 0.024 0.0591 0.0543
Echinococcus multilocularis slit 2 protein 0.0338 0.0982 0.0947
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0263 0.0682 0.0646
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.024 0.0591 0.0556
Onchocerca volvulus 0.0227 0.0542 0.1846
Echinococcus granulosus lachesin 0.0279 0.0749 0.0714
Brugia malayi GCC2 and GCC3 family protein 0.0779 0.2735 0.2735
Brugia malayi map kinase activated protein kinase protein 2 0.0803 0.2829 0.2829
Trichomonas vaginalis AGC family protein kinase 0.024 0.0592 0.1703
Plasmodium falciparum calcium-dependent protein kinase 5 0.0206 0.0456 0.0408
Echinococcus granulosus neurogenic locus notch protein 0.0293 0.0802 0.0767
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.037 0.1108 0.1074
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.016 0.0274 0.0224
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0151 0.0238 0.0238
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0231 0.0555 0.0519
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.0823 0.0823
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.024 0.0591 0.0556
Entamoeba histolytica PH domain containing protein kinase, putative 0.0335 0.0969 0.2944
Brugia malayi hypothetical protein 0.0453 0.1438 0.1438
Schistosoma mansoni protein kinase 0.0134 0.0171 0.0171
Echinococcus granulosus nervana 2 0.0252 0.0639 0.0603
Echinococcus granulosus NDR protein kinase 0.0328 0.0943 0.0908
Entamoeba histolytica protein kinase, putative 0.0283 0.0765 0.229
Onchocerca volvulus 0.0263 0.0682 0.232
Brugia malayi SRC-1 0.0311 0.0875 0.0875
Trichomonas vaginalis CMGC family protein kinase 0.0242 0.0602 0.1733
Loa Loa (eye worm) hypothetical protein 0.0279 0.0749 0.0749
Trichomonas vaginalis AGC family protein kinase 0.0278 0.0742 0.2174
Entamoeba histolytica protein kinase, putative 0.0249 0.063 0.1856
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0239 0.0239
Schistosoma mansoni hypothetical protein 0.0128 0.0148 0.0148
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0134 0.0171 0.012
Entamoeba histolytica protein kinase, putative 0.0166 0.03 0.0798
Brugia malayi Disorganized muscle protein 1 0.0128 0.0148 0.0148
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0334 0.0966 0.0966
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0417 0.0417
Trichomonas vaginalis STE family protein kinase 0.0132 0.0161 0.0346
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0151 0.0239 0.0239
Loa Loa (eye worm) TK protein kinase 0.0253 0.0645 0.0645
Plasmodium falciparum casein kinase 2, alpha subunit 0.0204 0.0451 0.0402
Echinococcus granulosus protein jagged 2 0.0293 0.0802 0.0767
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.024 0.0591 0.0569
Plasmodium falciparum apical sushi protein 0.0487 0.1572 0.1528
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0492 0.1595 0.1563
Loa Loa (eye worm) hypothetical protein 0.0787 0.2765 0.2765
Schistosoma mansoni serine/threonine protein kinase 0.0479 0.1542 0.1542
Echinococcus multilocularis cyclin dependent kinase 9 0.0164 0.0291 0.0254
Plasmodium falciparum protein serine/threonine kinase-1 0.0313 0.0884 0.0837
Schistosoma mansoni adapter molecule crk 0.0125 0.0135 0.0135
Echinococcus multilocularis neurogenic locus notch protein 0.0293 0.0802 0.0767
Echinococcus multilocularis cyclin dependent kinase 0.0242 0.0602 0.0566
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.024 0.0591 0.0556
Loa Loa (eye worm) hypothetical protein 0.0526 0.1728 0.1728
Schistosoma mansoni tyrosine kinase 0.0492 0.1595 0.1595
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0325 0.0928 0.0881
Echinococcus granulosus mitogen activated protein kinase 14 0.0325 0.0928 0.0893
Echinococcus multilocularis PAK box P21 Rho binding 0.0132 0.0161 0.0124
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0152 0.0244 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0884 0.0884
Trichomonas vaginalis AGC family protein kinase 0.0365 0.1088 0.3263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Brugia malayi Prion-like- 0.0128 0.0148 0.0148
Schistosoma mansoni titin 0.0128 0.0148 0.0148
Schistosoma mansoni protein kinase 0.024 0.0592 0.0592
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0231 0.0555 0.0519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0749 0.0749
Echinococcus granulosus peroxidasin 0.0371 0.1113 0.1079
Plasmodium falciparum thioredoxin reductase 0.0904 0.3229 0.3194
Plasmodium falciparum calcium-dependent protein kinase 4 0.0206 0.0456 0.0408
Schistosoma mansoni kinase 0.0588 0.1976 0.1976
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0904 0.3229 0.3229
Brugia malayi Protein kinase domain containing protein 0.0393 0.12 0.12
Trypanosoma cruzi cdc2-related kinase 3 0.0242 0.0602 0.0554
Schistosoma mansoni tyrosine kinase 0.0286 0.0774 0.0774
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0231 0.0555 0.0519
Trichomonas vaginalis CAMK family protein kinase 0.0551 0.1827 0.5588
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0466 0.1488 0.1456
Trichomonas vaginalis AGC family protein kinase 0.0596 0.2005 0.6148
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Schistosoma mansoni cell adhesion molecule 0.0151 0.0239 0.0239
Echinococcus multilocularis tyrosine protein kinase shark 0.0353 0.1041 0.1007
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0718 0.2493 0.2493
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.024 0.0591 0.1733
Echinococcus multilocularis tyrosine protein kinase otk 0.0279 0.0749 0.0714
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0231 0.0555 0.0519
Echinococcus multilocularis neurogenic locus notch protein 4 0.0293 0.0802 0.0767
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.024 0.0591 0.0556
Brugia malayi Protein kinase domain containing protein 0.0313 0.0881 0.0881
Schistosoma mansoni protein kinase 0.0884 0.3151 0.3151
Trichomonas vaginalis STE family protein kinase 0.0176 0.0337 0.0898
Mycobacterium ulcerans glutamate synthase subunit beta 0.024 0.0591 0.1694
Brugia malayi EGF-like domain containing protein 0.0293 0.0802 0.0802
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0283 0.0765 0.0718
Echinococcus multilocularis insulin receptor 0.0612 0.2069 0.2039
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) TK/INSR protein kinase 0.0612 0.2069 0.2069
Echinococcus multilocularis nervana 2 0.0252 0.0639 0.0603
Brugia malayi Protein kinase domain containing protein 0.0349 0.1027 0.1027
Brugia malayi Cyclin, N-terminal domain containing protein 0.0876 0.3119 0.3119
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0451 0.1257
Echinococcus granulosus dual specificity 0.0283 0.0765 0.073
Trichomonas vaginalis AGC family protein kinase 0.0345 0.101 0.3019
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Entamoeba histolytica protein kinase, putative 0.0135 0.0174 0.0396
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.024 0.0591 0.1694
Loa Loa (eye worm) LAD-2 short isoform 0.0151 0.0239 0.0239
Trichomonas vaginalis CAMK family protein kinase 0.0551 0.1827 0.5588
Brugia malayi Protein kinase domain containing protein 0.0133 0.0169 0.0169
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0497 0.1612 0.158
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0206 0.0456 0.0456
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0803 0.2829 0.2802
Brugia malayi putative serine/threonine kinase SADA gamma 0.016 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0487 0.1572 0.1572
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0151 0.0239 0.0202
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0129 0.0151 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Onchocerca volvulus 0.0293 0.0802 0.2731
Echinococcus granulosus serine/threonine protein kinase 0.0335 0.0969 0.0935
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0551 0.1827 0.1827
Echinococcus multilocularis casein kinase I delta 0.0222 0.052 0.0484
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0803 0.2829 0.2802
Trichomonas vaginalis glutathione reductase, putative 0.0904 0.3229 1
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0151 0.0239 0.0202
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0311 0.0875 0.084
Onchocerca volvulus 0.0391 0.1193 0.4063
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1176 0.431 0.431
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0451 0.1257
Entamoeba histolytica protein kinase domain containing protein 0.0204 0.0451 0.1282
Plasmodium vivax unspecified product 0.0204 0.0451 0.0428
Brugia malayi Protein kinase domain containing protein 0.0914 0.3269 0.3269
Echinococcus granulosus serine:threonine protein kinase MARK2 0.044 0.1388 0.1355
Schistosoma mansoni nck2/grb4 0.0125 0.0135 0.0135
Giardia lamblia Kinase, PLK 0.0551 0.1827 0.5588
Echinococcus multilocularis casein kinase I alpha 0.0222 0.052 0.0484
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0507 0.1654 0.1654
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0318 0.0318
Echinococcus granulosus dual specificity 0.0249 0.063 0.0594
Trypanosoma cruzi polo-like protein kinase, putative 0.0551 0.1827 0.1785
Brugia malayi Immunoglobulin I-set domain containing protein 0.0498 0.1618 0.1618
Brugia malayi Variant SH3 domain containing protein 0.0125 0.0135 0.0135
Loa Loa (eye worm) AUR protein kinase 0.024 0.0592 0.0592
Schistosoma mansoni protein kinase 0.0204 0.0451 0.0451
Schistosoma mansoni tyrosine kinase 0.013 0.0155 0.0155
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0319 0.0908 0.0873
Loa Loa (eye worm) hypothetical protein 0.0279 0.0749 0.0749
Trypanosoma cruzi casein kinase II, putative 0.0204 0.0451 0.0402
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0171 0.0318 0.0268
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.0318 0.084
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0298 0.0823 0.0788
Plasmodium falciparum calcium-dependent protein kinase 3 0.0206 0.0456 0.0408
Onchocerca volvulus 0.0662 0.2271 0.773
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.017 0.0313 0.0263
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0252 0.0639 0.0603
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0602 0.0602
Echinococcus granulosus calcium activated potassium channel 0.0275 0.0732 0.0696
Loa Loa (eye worm) TK/ABL protein kinase 0.0133 0.0169 0.0169
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0231 0.0555 0.0507
Brugia malayi hypothetical protein 0.0487 0.1572 0.1572
Echinococcus multilocularis mitogen activated protein kinase 14 0.0325 0.0928 0.0893
Giardia lamblia Kinase, AGC AKT 0.0239 0.0588 0.1689
Trichomonas vaginalis disulfide oxidoreductase, putative 0.024 0.0591 0.1701
Entamoeba histolytica glutamate synthase beta subunit, putative 0.024 0.0591 0.1733
Loa Loa (eye worm) hypothetical protein 0.0133 0.0169 0.0169
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.024 0.0591 0.0543
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0171 0.0318 0.0268
Brugia malayi hypothetical protein 0.0487 0.1572 0.1572
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.024 0.0591 0.1694
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.024 0.0591 0.0569
Brugia malayi Immunoglobulin domain containing protein 0.0151 0.0239 0.0239
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0231 0.0555 0.0507
Brugia malayi Protein kinase domain containing protein 0.0133 0.0169 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0497 0.1612 0.1612
Brugia malayi Protein kinase domain containing protein 0.0133 0.0169 0.0169
Onchocerca volvulus 0.0293 0.0802 0.2731
Echinococcus multilocularis fibropellin Ia 0.0293 0.0802 0.0767
Brugia malayi Variant SH3 domain containing protein 0.0125 0.0135 0.0135
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0222 0.0222
Onchocerca volvulus 0.0595 0.2002 0.6815
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0765 0.2246
Echinococcus multilocularis casein kinase i 0.0222 0.052 0.0484
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0128 0.0148 0.0111
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0189 0.039 0.0354
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.024 0.0591 0.0556
Trichomonas vaginalis STE family protein kinase 0.0176 0.0337 0.0898
Brugia malayi serine/threonine protein kinase 6 0.024 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0779 0.2735 0.2735
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0311 0.0875 0.084
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Trypanosoma cruzi NADH dehydrogenase, putative 0.024 0.0591 0.0543
Entamoeba histolytica protein kinase, putative 0.0186 0.0378 0.105
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Echinococcus granulosus c-Jun N-terminal kinases 0.0539 0.1778 0.1747
Brugia malayi Protein kinase domain containing protein 0.0395 0.1208 0.1208
Echinococcus multilocularis mitogen activated protein kinase 3 0.0171 0.0318 0.0281
Loa Loa (eye worm) hypothetical protein 0.0125 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0092 0.0005 0.0005
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.024 0.0591 0.0591
Schistosoma mansoni tyrosine kinase 0.0612 0.2069 0.2069
Loa Loa (eye worm) hypothetical protein 0.0246 0.0615 0.0615
Echinococcus multilocularis tyrosine protein kinase 0.0313 0.0881 0.0846
Brugia malayi Fibronectin type III domain containing protein 0.0526 0.1728 0.1728
Trichomonas vaginalis glutamate synthase, putative 0.024 0.0591 0.1701
Toxoplasma gondii aurora kinase 0.024 0.0592 0.0544
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.037 0.1108 0.1074
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0206 0.0456 0.042
Schistosoma mansoni protein kinase 0.045 0.1428 0.1428
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0151 0.0239 0.0239
Brugia malayi serine/threonine-protein kinase 6 0.024 0.0592 0.0592
Echinococcus granulosus casein kinase I alpha 0.0222 0.052 0.0484
Loa Loa (eye worm) hypothetical protein 0.0507 0.1654 0.1654
Brugia malayi protein kinase C II. 0.0416 0.1292 0.1292
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0129 0.0151 0.0113
Trypanosoma brucei aurora B kinase 0.024 0.0592 0.0544
Entamoeba histolytica protein kinase domain containing protein 0.0249 0.063 0.1856
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Trypanosoma cruzi p21-activated kinase 3, putative 0.0112 0.0083 0.0032
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0325 0.0928 0.0881
Brugia malayi Stress-activated protein kinase jnk-1 0.0539 0.1778 0.1778
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0206 0.0456 0.0434
Brugia malayi C1-like domain containing protein 0.0444 0.1401 0.1401
Entamoeba histolytica protein kinase, putative 0.0107 0.0062 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0555 0.0555
Echinococcus multilocularis 0.0196 0.0417 0.038
Echinococcus multilocularis notch 0.0293 0.0802 0.0767
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0263 0.0682 0.0634
Toxoplasma gondii AGC kinase 0.0231 0.0555 0.0507
Entamoeba histolytica serine/threonine protein kinase, putative 0.0551 0.1827 0.5696
Loa Loa (eye worm) hypothetical protein 0.0526 0.1728 0.1728
Brugia malayi SH2 domain containing protein 0.0445 0.1408 0.1408
Trypanosoma cruzi SNF1-related protein kinases, putative 0.016 0.0274 0.0224
Brugia malayi Protein kinase domain 0.0176 0.0337 0.0337
Brugia malayi Furin-like cysteine rich region family protein 0.0706 0.2446 0.2446
Echinococcus granulosus hemicentin 1 0.0279 0.0749 0.0714
Echinococcus granulosus cGMP dependent protein kinase 1 0.0172 0.0323 0.0286
Onchocerca volvulus Putative titin 0.0128 0.0148 0.0505
Trichomonas vaginalis STE family protein kinase 0.0176 0.0337 0.0898
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Brugia malayi Calcium binding EGF domain containing protein 0.0293 0.0802 0.0802
Trypanosoma brucei rac serine-threonine kinase, putative 0.0596 0.2005 0.1964
Trichomonas vaginalis CAMK family protein kinase 0.0551 0.1827 0.5588
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0278 0.0742 0.0695
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0215 0.0491 0.0491
Mycobacterium tuberculosis Probable oxidoreductase 0.0904 0.3229 0.2803
Schistosoma mansoni laminin gamma-3 chain 0.0293 0.0802 0.0802
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0451 0.1257
Brugia malayi Protein kinase domain containing protein 0.0309 0.0868 0.0868
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0293 0.0802 0.0802
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0231 0.0555 0.0507
Brugia malayi hypothetical protein 0.0487 0.1572 0.1572
Schistosoma mansoni hypothetical protein 0.0227 0.0542 0.0542
Loa Loa (eye worm) hypothetical protein 0.0526 0.1728 0.1728
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0279 0.0749 0.0749
Schistosoma mansoni g1/s-specific cyclin C 0.1751 0.6594 0.6594
Brugia malayi Protein kinase domain containing protein 0.0409 0.1265 0.1265
Echinococcus granulosus protein kinase C gamma type 0.0412 0.1274 0.1241
Echinococcus granulosus low density lipoprotein receptor ldl 0.0151 0.0239 0.0202
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.024 0.0591 0.0543
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0765 0.0765
Echinococcus multilocularis casein kinase I alpha 0.0222 0.052 0.0484
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Giardia lamblia Kinase, CMGC MAPK 0.0171 0.0318 0.084
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0592 0.0592
Leishmania major protein kinase, putative 0.0206 0.0456 0.0408
Loa Loa (eye worm) thyroid receptor interactor 0.0208 0.0466 0.0466
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0235 0.0572 0.0536
Schistosoma mansoni protein kinase 0.0884 0.3151 0.3151
Loa Loa (eye worm) disorganized muscle protein 1 0.0128 0.0148 0.0148
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0231 0.0555 0.0507
Entamoeba histolytica protein kinase, putative 0.0147 0.0222 0.055
Echinococcus multilocularis transfer RNA-Phe 0.0147 0.0222 0.0185
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.024 0.0591 0.0543
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0249 0.063 0.063
Entamoeba histolytica protein kinase domain containing protein 0.024 0.0592 0.1736
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0195 0.0412 0.0375
Trichomonas vaginalis STE family protein kinase 0.0278 0.0742 0.2174
Loa Loa (eye worm) hypothetical protein 0.0227 0.0542 0.0542
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0166 0.03 0.03
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0163 0.0286 0.0249
Loa Loa (eye worm) CAMK protein kinase 0.0215 0.0491 0.0491
Plasmodium vivax glycogen synthase kinase 3, putative 0.0263 0.0682 0.066
Echinococcus granulosus rho-associated protein kinase 1 0.0662 0.2271 0.2241
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0409 0.1265 0.1265
Echinococcus granulosus cGMP dependent protein kinase 1 0.0172 0.0323 0.0286
Giardia lamblia Kinase, STE STE20 0.0176 0.0337 0.0898
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0227 0.0542 0.0494
Echinococcus granulosus protein jagged 1 0.0293 0.0802 0.0767
Echinococcus multilocularis cyclin dependent kinase 5 0.0242 0.0602 0.0566
Brugia malayi Immunoglobulin I-set domain containing protein 0.0526 0.1728 0.1728
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0328 0.0943 0.0908
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0747 0.2607 0.2579
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0765 0.2246
Echinococcus granulosus hypothetical protein 0.0246 0.0615 0.0579
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0311 0.0875 0.084
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0242 0.0602 0.0554
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0206 0.0456 0.0408
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0551 0.1827 0.1785
Echinococcus multilocularis casein kinase I gamma 0.0435 0.1366 0.1333
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0259 0.0667 0.0632
Trichomonas vaginalis CAMK family protein kinase 0.0551 0.1827 0.5588
Echinococcus granulosus nephrin 0.0147 0.0222 0.0185
Brugia malayi intracellular kinase 0.0263 0.0682 0.0682
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0904 0.3229 0.3194
Giardia lamblia Kinase, STE STE20 0.0173 0.0326 0.0864
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0274 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.063 0.063
Schistosoma mansoni serine/threonine protein kinase 0.0416 0.1292 0.1292
Plasmodium falciparum calcium-dependent protein kinase 2 0.0206 0.0456 0.0408
Mycobacterium ulcerans ferredoxin reductase 0.024 0.0591 0.1694
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.0943 0.0943
Brugia malayi Protein kinase domain containing protein 0.0133 0.0169 0.0169
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0242 0.0602 0.0554
Schistosoma mansoni tyrosine kinase 0.0612 0.2069 0.2069
Echinococcus multilocularis netrin receptor unc 5 0.021 0.0473 0.0436
Brugia malayi hypothetical protein 0.0092 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.1176 0.431 0.431
Echinococcus multilocularis serine:threonine protein kinase N2 0.0592 0.1992 0.1961
Brugia malayi hypothetical protein 0.0487 0.1572 0.1572
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.024 0.0591 0.1733
Echinococcus granulosus raf serine:threonine protein kinase 0.0151 0.024 0.0203
Echinococcus multilocularis neuroglian 0.0298 0.0823 0.0788
Brugia malayi Protein kinase domain containing protein 0.0133 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0658 0.2255 0.2255
Onchocerca volvulus 0.0128 0.0148 0.0505
Brugia malayi EGF-like domain containing protein 0.0293 0.0802 0.0802
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0904 0.3229 0.3194
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0166 0.0296 0.0246
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0904 0.3229 1
Loa Loa (eye worm) hypothetical protein 0.022 0.0512 0.0512
Schistosoma mansoni serine/threonine protein kinase 0.0803 0.2829 0.2829
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.05 0.1623 0.1591
Plasmodium vivax serine/threonine kinase-1, putative 0.0313 0.0884 0.0862
Echinococcus multilocularis serine:threonine protein kinase 3 0.0523 0.1718 0.1687
Trichomonas vaginalis CAMK family protein kinase 0.0442 0.1396 0.4232
Plasmodium falciparum calcium-dependent protein kinase 1 0.0206 0.0456 0.0408
Echinococcus granulosus cyclin dependent kinase 0.0242 0.0602 0.0566
Loa Loa (eye worm) hypothetical protein 0.0283 0.0761 0.0761
Echinococcus multilocularis tyrosine kinase 0.0133 0.0169 0.0131
Echinococcus granulosus casein kinase I delta 0.0222 0.052 0.0484
Echinococcus granulosus Immunoglobulin 0.0151 0.0239 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.052 0.1704 0.1704
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.017 0.0313 0.0276
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0335 0.0969 0.0923
Brugia malayi hypothetical protein 0.0526 0.1728 0.1728
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.024 0.0591 0.0543
Schistosoma mansoni protein kinase 0.0176 0.0337 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Echinococcus multilocularis fibroblast growth factor receptor 4 0.037 0.1108 0.1074
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0172 0.0323 0.0286
Trichomonas vaginalis AGC family protein kinase 0.0166 0.03 0.0783
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0444 0.1401 0.1401
Toxoplasma gondii selenide, water dikinase 0.024 0.0591 0.0543
Entamoeba histolytica protein kinase domain containing protein 0.0164 0.0291 0.0771
Leishmania major casein kinase, putative 0.0222 0.052 0.0471
Echinococcus multilocularis Immunoglobulin 0.0507 0.1654 0.1622
Brugia malayi protein unc-22 0.0215 0.0491 0.0491
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0904 0.3229 0.3194
Schistosoma mansoni roundabout 0.0279 0.0749 0.0749
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0151 0.0239 0.0202
Schistosoma mansoni tyrosine kinase 0.0426 0.1332 0.1332
Onchocerca volvulus Serine\/threonine kinase homolog 0.0551 0.1827 0.622
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.017 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0108 0.0068 0.0068
Loa Loa (eye worm) TK/ALK protein kinase 0.0309 0.0868 0.0868
Loa Loa (eye worm) hypothetical protein 0.0291 0.0794 0.0794
Echinococcus granulosus protein jagged 1 0.0293 0.0802 0.0767
Echinococcus multilocularis death associated protein kinase 1 0.0906 0.3239 0.3213
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0453 0.1438 0.1406
Echinococcus multilocularis protein tyrosine kinase 0.0587 0.1969 0.1939
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.024 0.0591 0.1694
Onchocerca volvulus 0.0113 0.0088 0.03
Trichomonas vaginalis AGC family protein kinase 0.0166 0.03 0.0783
Echinococcus granulosus mitogen activated protein kinase 3 0.0171 0.0318 0.0281
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0166 0.03 0.0263
Echinococcus granulosus twitchin 0.0703 0.2433 0.2404
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.016 0.0274 0.0274
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0231 0.0555 0.0519
Schistosoma mansoni tyrosine kinase 0.0492 0.1595 0.1595
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0125 0.0135 0.0135
Echinococcus granulosus mitogen activated protein kinase 11 0.0325 0.0928 0.0893
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.024 0.0591 0.0543
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0319 0.0908 0.0886
Echinococcus granulosus protein jagged 2 0.0293 0.0802 0.0767
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0147 0.0222 0.0222
Brugia malayi Sex muscle abnormal protein 5 0.0125 0.0135 0.0135
Brugia malayi Protein kinase domain containing protein 0.0183 0.0367 0.0367
Schistosoma mansoni tyrosine kinase 0.0706 0.2446 0.2446
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Onchocerca volvulus Peroxidasin homolog 0.0219 0.051 0.1736
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0249 0.063 0.0581
Echinococcus multilocularis protein kinase c iota type 0.0582 0.1952 0.1921
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0413 0.128 0.1246
Echinococcus multilocularis twitchin 0.0196 0.0417 0.0381
Loa Loa (eye worm) hypothetical protein 0.0247 0.0618 0.0618
Trypanosoma brucei protein kinase, putative 0.0263 0.0682 0.0634
Loa Loa (eye worm) hypothetical protein 0.0651 0.2224 0.2224
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0507 0.1654 0.1622
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Echinococcus granulosus titin 0.0215 0.0491 0.0455
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0335 0.0968 0.0934
Brugia malayi Protein kinase domain containing protein 0.0127 0.0141 0.0141
Echinococcus multilocularis neuroglian 0.0636 0.2164 0.2134
Echinococcus granulosus tyrosine protein kinase Blk 0.0253 0.0645 0.061
Giardia lamblia NADH oxidase lateral transfer candidate 0.0904 0.3229 1
Echinococcus multilocularis protein jagged 1 0.0293 0.0802 0.0767
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0148 0.0148
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0876 0.3119 0.3093
Giardia lamblia Kinase, AGC PKA 0.0319 0.0908 0.2696
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0409 0.1264 0.1231
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.044 0.1388 0.1355
Echinococcus multilocularis cyclin dependent kinase 1 0.0242 0.0602 0.0566
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0747 0.2607 0.2579
Trypanosoma brucei RNA helicase, putative 0.0153 0.0247 0.0197
Toxoplasma gondii AGC kinase 0.058 0.1943 0.1902
Plasmodium falciparum glycogen synthase kinase 3 0.0263 0.0682 0.0634
Brugia malayi hypothetical protein 0.0227 0.0542 0.0542
Echinococcus multilocularis nervana 2 0.0252 0.0639 0.0603
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0279 0.0749 0.0749
Toxoplasma gondii CMGC kinase, CK2 family 0.0204 0.0451 0.0402
Plasmodium vivax serine/threonine protein kinase 6, putative 0.024 0.0592 0.057
Schistosoma mansoni kinase 0.0164 0.0291 0.0291
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0222 0.0222
Brugia malayi pregnancy-associated plasma protein-A 0.0487 0.1572 0.1572
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0166 0.0296 0.0246
Plasmodium vivax protein kinase Crk2 0.0242 0.0602 0.058
Schistosoma mansoni protein kinase 0.0312 0.088 0.088
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0328 0.0943 0.0908
Brugia malayi Immunoglobulin I-set domain containing protein 0.136 0.5044 0.5044
Echinococcus multilocularis raf serine:threonine protein kinase 0.0151 0.024 0.0203
Echinococcus granulosus titin 0.0128 0.0148 0.0111
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) hypothetical protein 0.0283 0.0761 0.0761
Echinococcus multilocularis rho associated protein kinase 0.0662 0.2271 0.2241
Brugia malayi EGF-like domain containing protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) AGC/PKA protein kinase 0.0231 0.0555 0.0555
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0328 0.0943 0.0908
Echinococcus multilocularis expressed protein 0.017 0.0313 0.0276
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0313 0.0884 0.0837
Loa Loa (eye worm) TK protein kinase 0.0313 0.0881 0.0881
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0451 0.1257
Onchocerca volvulus Netrin receptor homolog 0.0187 0.0382 0.1302
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.0572 0.1638
Brugia malayi Immunoglobulin I-set domain containing protein 0.0298 0.0823 0.0823
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.024 0.0591 0.0543
Brugia malayi basement membrane proteoglycan 0.0151 0.0239 0.0239
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0466 0.1488 0.1456
Loa Loa (eye worm) hypothetical protein 0.0376 0.1132 0.1132
Echinococcus granulosus protein kinase 0.0312 0.088 0.0845
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0148 0.0148
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0104 0.0052 0.0004
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0235 0.0572 0.0536
Brugia malayi Casein kinase II, alpha chain 0.0204 0.0451 0.0451
Brugia malayi serine/threonine kinase 12 0.024 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0147 0.0222 0.0222
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0151 0.0239 0.0202
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0904 0.3229 1
Entamoeba histolytica casein kinase, putative 0.0204 0.0451 0.1282
Brugia malayi Protein kinase domain containing protein 0.0233 0.0564 0.0564
Brugia malayi Temporarily assigned gene name protein 59 0.0227 0.0542 0.0542
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0252 0.0639 0.0603
Trichomonas vaginalis AGC family protein kinase 0.0231 0.0555 0.1586
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0283 0.0765 0.0718
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0313 0.0313
Trichomonas vaginalis AGC family protein kinase 0.0596 0.2005 0.6148
Trichomonas vaginalis AGC family protein kinase 0.024 0.0592 0.1703
Brugia malayi Heparan sulfate 0.0151 0.0239 0.0239
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0319 0.0908 0.0861
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Schistosoma mansoni hypothetical protein 0.0151 0.0239 0.0239
Echinococcus granulosus tyrosine protein kinase Srms 0.0553 0.1834 0.1803
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0325 0.0928 0.0881
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0904 0.3229 0.3194
Plasmodium falciparum casein kinase 1 0.0222 0.052 0.0471
Trichomonas vaginalis CMGC family protein kinase 0.0242 0.0602 0.1733
Echinococcus multilocularis Immunoglobulin 0.0151 0.0239 0.0202
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0176 0.0337 0.03
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0263 0.0682 0.0682
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0323 0.0323
Echinococcus multilocularis titin 0.0215 0.0491 0.0455
Loa Loa (eye worm) hypothetical protein 0.0379 0.1145 0.1145
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0312 0.088 0.088
Schistosoma mansoni hypothetical protein 0.0153 0.0247 0.0247
Onchocerca volvulus 0.0129 0.0151 0.0513
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0904 0.3229 0.3194
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0295 0.0811 0.0776
Echinococcus multilocularis tyrosine protein kinase HCK 0.0186 0.0378 0.0342
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0311 0.0875 0.084
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0173 0.0326 0.0276
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0171 0.0318 0.0268
Onchocerca volvulus Slit protein homolog 0.0338 0.0982 0.3342
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.024 0.0591 0.0543
Schistosoma mansoni protein kinase 0.0222 0.052 0.052
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.024 0.0591 0.0556
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0191 0.0398 0.0398
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0128 0.0148 0.0148
Brugia malayi Delta serrate ligand family protein 0.0293 0.0802 0.0802
Toxoplasma gondii rhoptry neck protein RON9 0.0487 0.1572 0.1528
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0453 0.1438 0.1438
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0904 0.3229 0.3194
Trypanosoma cruzi hypothetical protein, conserved 0.024 0.0591 0.0543
Echinococcus multilocularis Immunoglobulin 0.0151 0.0239 0.0202
Echinococcus granulosus fibropellin Ia 0.0293 0.0802 0.0767
Schistosoma mansoni serine/threonine protein kinase 0.0539 0.1778 0.1778
Loa Loa (eye worm) hypothetical protein 0.0227 0.0542 0.0542
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0151 0.0239 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0972 0.3499 0.3499
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.0572 0.1638
Loa Loa (eye worm) hypothetical protein 0.0508 0.1656 0.1656
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0133 0.0169 0.0131
Echinococcus granulosus protein kinase shaggy 0.0263 0.0682 0.0646
Entamoeba histolytica protein kinase, putative 0.0249 0.063 0.1856
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Giardia lamblia Kinase, CMGC DYRK 0.0283 0.0765 0.2246
Loa Loa (eye worm) programmed cell death 8 0.024 0.0591 0.0591
Schistosoma mansoni protein kinase 0.0747 0.2607 0.2607
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0263 0.0682 0.0682
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0551 0.1827 0.1796
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0551 0.1827 0.1796
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.017 0.0313 0.0313
Schistosoma mansoni hypothetical protein 0.0151 0.0239 0.0239
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0914 0.3269 0.3269
Trichomonas vaginalis CMGC family protein kinase 0.0242 0.0602 0.1733
Echinococcus multilocularis roundabout 2 0.0805 0.2838 0.2811
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Brugia malayi Protein kinase domain containing protein 0.0328 0.0943 0.0943
Plasmodium falciparum serine/threonine protein kinase, putative 0.024 0.0592 0.0544
Loa Loa (eye worm) hypothetical protein 0.013 0.0156 0.0156
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0339 0.0984 0.0949
Brugia malayi EGF-like domain containing protein 0.0338 0.0982 0.0982
Echinococcus granulosus fibroblast growth factor receptor 4 0.037 0.1108 0.1074
Entamoeba histolytica disulphide oxidoreductase, putative 0.024 0.0591 0.1733
Brugia malayi Immunoglobulin I-set domain containing protein 0.0215 0.0491 0.0491
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Echinococcus multilocularis mitogen activated protein kinase 11 0.0325 0.0928 0.0893
Trypanosoma brucei cdc2-related kinase 3 0.0242 0.0602 0.0554
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0125 0.0135 0.0135
Brugia malayi Serine/threonine-protein kinase SULU 0.0453 0.1438 0.1438
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Brugia malayi Protein kinase domain containing protein 0.0249 0.063 0.063
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0904 0.3229 1
Onchocerca volvulus 0.0128 0.0148 0.0505
Brugia malayi Cam kinase protein 1 0.0206 0.0456 0.0456
Echinococcus granulosus CDC7 cell division cycle 7 0.0183 0.0367 0.033
Onchocerca volvulus 0.0133 0.0169 0.0574
Echinococcus multilocularis dual specificity protein kinase clk2 0.0313 0.0884 0.0849
Echinococcus multilocularis cyclin dependent kinase 1 0.0242 0.0602 0.0566
Loa Loa (eye worm) CDC7 protein kinase 0.0183 0.0367 0.0367
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0183 0.0367 0.0367
Schistosoma mansoni ste20-related kinase 0.0418 0.13 0.13
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0366 0.1091 0.1091
Schistosoma mansoni neuroglian 0.0298 0.0823 0.0823
Entamoeba histolytica casein kinase, putative 0.0222 0.052 0.1503
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0445 0.1408 0.1375
Echinococcus granulosus Immunoglobulin 0.0151 0.0239 0.0202
Schistosoma mansoni hypothetical protein 0.0151 0.0239 0.0239
Schistosoma mansoni atypical protein kinase C 0.0595 0.2001 0.2001
Giardia lamblia Kinase, CMGC GSK 0.0263 0.0682 0.1984
Loa Loa (eye worm) TK/EPH protein kinase 0.0232 0.0561 0.0561
Echinococcus granulosus cyclin 0.0876 0.3119 0.3093
Brugia malayi Prion-like- 0.0128 0.0148 0.0148
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0176 0.0337 0.03
Onchocerca volvulus 0.0133 0.0169 0.0574
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Echinococcus granulosus cyclin dependent kinase 9 0.0164 0.0291 0.0254
Echinococcus granulosus titin 0.0128 0.0148 0.0111
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0651 0.2224 0.2224
Brugia malayi Immunoglobulin I-set domain containing protein 0.021 0.0473 0.0473
Leishmania major protein kinase, putative 0.0134 0.0171 0.012
Echinococcus multilocularis lachesin 0.0279 0.0749 0.0714
Schistosoma mansoni netrin receptor unc5 0.021 0.0473 0.0473
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.024 0.0591 0.1701
Echinococcus multilocularis neurogenic locus protein delta 0.0293 0.0802 0.0767
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0112 0.0083 0.0083
Brugia malayi EGF-like domain containing protein 0.0293 0.0802 0.0802
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0323 0.0323
Echinococcus granulosus roundabout 2 0.0805 0.2838 0.2811
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0253 0.0645 0.061
Schistosoma mansoni tyrosine kinase 0.0426 0.1332 0.1332
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.044 0.1388 0.1355
Toxoplasma gondii histone kinase SNF1, putative 0.016 0.0274 0.0224
Echinococcus granulosus leucine rich repeat containing protein 4 0.0128 0.0148 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0083 0.0083
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0311 0.0875 0.084
Trypanosoma cruzi cdc2-related kinase 3 0.0242 0.0602 0.0554
Loa Loa (eye worm) hypothetical protein 0.0206 0.0456 0.0456
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0171 0.0318 0.0268
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.024 0.0591 0.0543
Echinococcus multilocularis glutamate synthase 0.024 0.0591 0.0556
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0206 0.0456 0.0434
Echinococcus multilocularis calcium dependent protein kinase 0.0138 0.0188 0.015
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0263 0.0682 0.0682
Schistosoma mansoni tyrosine kinase 0.0191 0.0398 0.0398
Brugia malayi P38 map kinase family protein 2 0.0325 0.0928 0.0928
Brugia malayi Immunoglobulin I-set domain containing protein 0.017 0.0313 0.0313
Echinococcus granulosus tyrosine protein kinase Lyn 0.0379 0.1144 0.111
Loa Loa (eye worm) hypothetical protein 0.0147 0.0222 0.0222
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0171 0.0318 0.0318
Trypanosoma cruzi casein kinase, putative 0.0222 0.052 0.0471
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1007 0.364 0.3615
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0134 0.0171 0.012
Echinococcus multilocularis cyclin dependent kinase 9 0.0181 0.0359 0.0322
Echinococcus granulosus growth factor receptor bound protein 2 0.0127 0.0143 0.0106
Schistosoma mansoni protein kinase 0.0393 0.12 0.12
Echinococcus granulosus roundabout 2 0.0298 0.0823 0.0788
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.024 0.0591 0.1701
Brugia malayi hypothetical protein 0.0151 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0279 0.0749 0.0749
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0279 0.0749 0.0749
Schistosoma mansoni protein kinase 0.0884 0.3151 0.3151
Loa Loa (eye worm) TK protein kinase 0.0378 0.1141 0.1141
Echinococcus multilocularis Glutaredoxin protein 5 0.0252 0.0639 0.0603
Brugia malayi Animal haem peroxidase family protein 0.0219 0.051 0.051
Schistosoma mansoni septate junction protein 0.0151 0.0239 0.0239
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0349 0.1027 0.1027
Brugia malayi Prion-like- 0.0128 0.0148 0.0148
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0206 0.0456 0.0456
Onchocerca volvulus 0.0183 0.0367 0.1249
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Loa Loa (eye worm) AUR protein kinase 0.024 0.0592 0.0592
Echinococcus multilocularis rac serine:threonine kinase 0.0335 0.0969 0.0935
Entamoeba histolytica glutamate synthase beta subunit, putative 0.024 0.0591 0.1733
Brugia malayi Protein kinase domain containing protein 0.0435 0.1366 0.1366
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.0068 0.0052
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0319 0.0908 0.0873
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Toxoplasma gondii NADPH-glutathione reductase 0.0904 0.3229 0.3194
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0263 0.0682 0.0634
Echinococcus granulosus aurora kinase A 0.024 0.0592 0.0556
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0328 0.0328
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0904 0.3229 0.2803
Trichomonas vaginalis AGC family protein kinase 0.0349 0.1027 0.307
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Echinococcus multilocularis serine:threonine kinase SAD 1 0.016 0.0274 0.0236
Mycobacterium ulcerans dehydrogenase 0.024 0.0591 0.1694
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0664 0.2276 0.2276
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.052 0.052
Brugia malayi Sushi domain 0.0487 0.1572 0.1572
Brugia malayi hypothetical protein 0.0487 0.1572 0.1572
Trichomonas vaginalis STE family protein kinase 0.0176 0.0337 0.0898
Entamoeba histolytica cyclin C, putative 0.0888 0.3169 1
Echinococcus multilocularis titin 0.0128 0.0148 0.0111
Schistosoma mansoni titin 0.0128 0.0148 0.0148
Onchocerca volvulus 0.0128 0.0148 0.0505
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0283 0.0765 0.0765
Onchocerca volvulus 0.0147 0.0222 0.0756
Schistosoma mansoni hypothetical protein 0.0128 0.0148 0.0148
Echinococcus multilocularis neurogenic locus protein delta 0.0293 0.0802 0.0767
Brugia malayi Cadherin domain containing protein 0.0293 0.0802 0.0802
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Echinococcus granulosus basement membrane specific heparan sulfate 0.0151 0.0239 0.0202
Mycobacterium ulcerans hypothetical protein 0.024 0.0591 0.1694
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0227 0.0542 0.0506
Trichomonas vaginalis disulfide oxidoreductase, putative 0.024 0.0591 0.1701
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0313 0.0884 0.0837
Loa Loa (eye worm) hypothetical protein 0.0939 0.3371 0.3371
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0151 0.0239 0.0239
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0298 0.0823 0.0823
Onchocerca volvulus 0.0154 0.0251 0.0854
Loa Loa (eye worm) hypothetical protein 0.0101 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Schistosoma mansoni tyrosine kinase 0.0191 0.0398 0.0398
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.024 0.0591 0.1701
Trypanosoma cruzi casein kinase, putative 0.0222 0.052 0.0471
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0287 0.078 0.0745
Brugia malayi EGF-like domain containing protein 0.0293 0.0802 0.0802
Echinococcus multilocularis casein kinase ii subunit alpha 0.0204 0.0451 0.0414
Echinococcus granulosus netrin receptor unc 5 0.021 0.0473 0.0436
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0107 0.0062 0.0024
Echinococcus granulosus cyclin dependent kinase 5 0.0242 0.0602 0.0566
Schistosoma mansoni notch 0.0293 0.0802 0.0802
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0904 0.3229 0.3194
Schistosoma mansoni protein kinase 0.0176 0.0337 0.0337
Schistosoma mansoni hypothetical protein 0.0128 0.0148 0.0148
Brugia malayi Protein kinase domain containing protein 0.0718 0.2493 0.2493
Loa Loa (eye worm) TK protein kinase 0.0186 0.0378 0.0378
Echinococcus multilocularis hemicentin 1 0.0279 0.0749 0.0714
Echinococcus granulosus serine:threonine protein kinase 0.0233 0.0564 0.0528
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0732 0.0732
Echinococcus multilocularis roundabout 2 0.0298 0.0823 0.0788
Brugia malayi hypothetical protein 0.0487 0.1572 0.1572
Echinococcus granulosus tyrosine protein kinase Fyn 0.0311 0.0875 0.084
Echinococcus granulosus serine:threonine protein kinase 3 0.0523 0.1718 0.1687
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0749 0.0749
Trichomonas vaginalis CAMK family protein kinase 0.0233 0.0564 0.1614
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Schistosoma mansoni hypothetical protein 0.0293 0.0802 0.0802
Onchocerca volvulus 0.0128 0.0148 0.0505
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0413 0.128 0.128
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Trichomonas vaginalis mercuric reductase, putative 0.0904 0.3229 1
Loa Loa (eye worm) TK/FER protein kinase 0.0445 0.1408 0.1408
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.016 0.0274 0.0224
Schistosoma mansoni cell adhesion molecule 0.0677 0.2328 0.2328
Echinococcus granulosus sulfide:quinone oxidoreductase 0.024 0.0591 0.0556
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0904 0.3229 0.2803
Brugia malayi Doublecortin family protein 0.0308 0.0861 0.0861
Onchocerca volvulus 0.0133 0.0169 0.0574
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0242 0.0602 0.0554
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.024 0.0591 0.0556
Schistosoma mansoni rap gtpase-activating protein 0.0227 0.0542 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0451 0.1257
Echinococcus granulosus calcium dependent protein kinase 0.0138 0.0188 0.015
Onchocerca volvulus 0.0293 0.0802 0.2731
Loa Loa (eye worm) hypothetical protein 0.0092 0.0005 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0904 0.3229 0.3194
Trichomonas vaginalis AGC family protein kinase 0.0596 0.2005 0.6148
Giardia lamblia Kinase, AGC PKA 0.0231 0.0555 0.1586
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0507 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Trichomonas vaginalis AGC family protein kinase 0.0596 0.2005 0.6148
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Schistosoma mansoni protein kinase 0.054 0.1783 0.1783
Onchocerca volvulus 0.0487 0.1572 0.535
Brugia malayi protein-tyrosine kinase 0.0253 0.0645 0.0645
Loa Loa (eye worm) TK/FAK protein kinase 0.0593 0.1994 0.1994
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0151 0.0239 0.0239
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Giardia lamblia Kinase, CMGC CDK 0.0242 0.0602 0.1733
Echinococcus granulosus notch 0.0293 0.0802 0.0767
Brugia malayi hypothetical protein 0.0487 0.1572 0.1572
Entamoeba histolytica protein kinase, putative 0.0263 0.0682 0.2022
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0311 0.0875 0.084
Loa Loa (eye worm) AGC/AKT protein kinase 0.0596 0.2005 0.2005
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1254 0.462 0.462
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0718 0.2493 0.2493
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0147 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0293 0.0802 0.0802
Trypanosoma cruzi cdc2-related kinase 1 0.0242 0.0602 0.0554
Brugia malayi Peroxidasin 0.0371 0.1113 0.1113
Brugia malayi Temporarily assigned gene name protein 59 0.0263 0.0682 0.0682
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0413 0.128 0.128
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0152 0.0244 0.0207
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0222 0.052 0.0471
Brugia malayi Protein kinase domain containing protein 0.0747 0.2607 0.2607
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0278 0.0742 0.072
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0904 0.3229 0.3213
Schistosoma mansoni cell adhesion molecule 0.0147 0.0222 0.0222
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0325 0.0928 0.0881
Entamoeba histolytica protein kinase, putative 0.0596 0.2005 0.6266
Trichomonas vaginalis AGC family protein kinase 0.0596 0.2005 0.6148
Giardia lamblia High cysteine protein 0.0293 0.0802 0.2363
Brugia malayi basement membrane proteoglycan precursor 0.0151 0.0239 0.0239
Trypanosoma brucei Casein kinase II 0.0204 0.0451 0.0402
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Plasmodium falciparum ferrodoxin reductase-like protein 0.024 0.0591 0.0543
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0172 0.0323 0.0286
Loa Loa (eye worm) hypothetical protein 0.0279 0.0749 0.0749
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0231 0.0555 0.0507
Onchocerca volvulus Serine\/threonine kinase homolog 0.0335 0.0968 0.3296
Entamoeba histolytica protein kinase, putative 0.024 0.0592 0.1736
Schistosoma mansoni vav2 0.0168 0.0305 0.0305
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0206 0.0456 0.042
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0171 0.0318 0.0268
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.024 0.0591 0.1733
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0335 0.0968 0.0968
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0319 0.0908 0.0861
Loa Loa (eye worm) projectin 0.0147 0.0222 0.0222
Schistosoma mansoni serine/threonine-protein kinase 0.0335 0.0969 0.0969
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.024 0.0591 0.0591
Schistosoma mansoni hypothetical protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) Notch2 0.0293 0.0802 0.0802
Echinococcus multilocularis cyclin 0.0876 0.3119 0.3093
Trichomonas vaginalis AGC family protein kinase 0.0596 0.2005 0.6148
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0206 0.0456 0.0408
Entamoeba histolytica thioredoxin reductase, putative 0.024 0.0591 0.1733
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Schistosoma mansoni septate junction protein 0.0151 0.0239 0.0239
Echinococcus multilocularis peroxidasin 0.0371 0.1113 0.1079
Giardia lamblia Kinase, NEK 0.0278 0.0742 0.2174
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0678 0.2333 0.2333
Schistosoma mansoni hypothetical protein 0.0293 0.0802 0.0802
Trypanosoma cruzi NADH dehydrogenase, putative 0.024 0.0591 0.0543
Trichomonas vaginalis AGC family protein kinase 0.024 0.0592 0.1703
Loa Loa (eye worm) casein kinase 0.0367 0.1097 0.1097
Onchocerca volvulus 0.0487 0.1572 0.535
Echinococcus multilocularis activin receptor type 0.0134 0.0171 0.0133
Schistosoma mansoni hypothetical protein 0.0207 0.0463 0.0463
Echinococcus multilocularis casein kinase I alpha 0.0222 0.052 0.0484
Schistosoma mansoni nephrin related 0.0151 0.0239 0.0239
Schistosoma mansoni protein kinase C mu 0.0444 0.1401 0.1401
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0451 0.1257
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.017 0.0313 0.0263
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.024 0.0591 0.1701
Trypanosoma cruzi casein kinase, putative 0.0222 0.052 0.0471
Brugia malayi Protein kinase domain containing protein 0.0612 0.2069 0.2069
Onchocerca volvulus 0.0147 0.0222 0.0756
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0173 0.0326 0.0276
Loa Loa (eye worm) hypothetical protein 0.0182 0.0361 0.0361
Loa Loa (eye worm) TK/EGFR protein kinase 0.0706 0.2446 0.2446
Entamoeba histolytica hypothetical protein 0.0249 0.063 0.1856
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0242 0.0602 0.0602
Brugia malayi Protein kinase domain containing protein 0.0166 0.03 0.03
Schistosoma mansoni serine/threonine protein kinase 0.044 0.1388 0.1388
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0231 0.0555 0.0555
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Schistosoma mansoni cell adhesion molecule 0.0298 0.0823 0.0823
Trichomonas vaginalis apoptosis inducing factor, putative 0.024 0.0591 0.1701
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0135 0.0174 0.0396
Loa Loa (eye worm) hypothetical protein 0.0175 0.0333 0.0333
Giardia lamblia Kinase, NEK 0.0278 0.0742 0.2174
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0206 0.0456 0.042
Echinococcus granulosus casein kinase ii subunit alpha 0.0204 0.0451 0.0414
Echinococcus granulosus tyrosine protein kinase 0.0313 0.0881 0.0846
Echinococcus granulosus Glutaredoxin protein 5 0.0252 0.0639 0.0603
Onchocerca volvulus 0.0293 0.0802 0.2731
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0904 0.3229 1
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.0242 0.0601 0.0601
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0325 0.0928 0.0928
Onchocerca volvulus 0.024 0.0591 0.2014
Echinococcus granulosus serine threonine protein kinase nrc 0.0319 0.0908 0.0873
Echinococcus multilocularis titin 0.0128 0.0148 0.0111
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0409 0.1264 0.1231
Giardia lamblia Kinase, CMGC SRPK 0.017 0.0313 0.0824
Echinococcus multilocularis fat cadherin tumor suppressor 0.0293 0.0802 0.0767
Onchocerca volvulus Peroxidasin homolog 0.022 0.0512 0.1743
Onchocerca volvulus 0.0283 0.0761 0.2591
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0732 0.0732
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0904 0.3229 0.3229
Echinococcus granulosus tyrosine protein kinase Fyn 0.0311 0.0875 0.084
Schistosoma mansoni notch 0.0293 0.0802 0.0802
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0718 0.2493 0.8486
Entamoeba histolytica protein kinase 2, putative 0.0319 0.0908 0.2748
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0176 0.0337 0.03
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Echinococcus multilocularis c4b binding protein beta chain 0.0487 0.1572 0.1539
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0295 0.0812 0.0777
Toxoplasma gondii AGC kinase 0.0231 0.0555 0.0507
Brugia malayi Protein kinase domain containing protein 0.0596 0.2005 0.2005
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.024 0.0591 0.0591
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Schistosoma mansoni titin 0.0279 0.0749 0.0749
Brugia malayi Variant SH3 domain containing protein 0.0152 0.0244 0.0244
Onchocerca volvulus 0.0487 0.1572 0.535
Trichomonas vaginalis disulfide oxidoreductase, putative 0.024 0.0591 0.1701
Entamoeba histolytica protein kinase, putative 0.024 0.0592 0.1736
Echinococcus granulosus nervana 2 0.0252 0.0639 0.0603
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0747 0.2607 0.2607
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0151 0.0239 0.0202
Schistosoma mansoni slit 0.0293 0.0804 0.0804
Echinococcus granulosus NCK adaptor protein 0.0125 0.0135 0.0098
Echinococcus multilocularis protein kinase shaggy 0.0263 0.0682 0.0646
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.024 0.0591 0.0543
Plasmodium vivax casein kinase 1, putative 0.0222 0.052 0.0497
Schistosoma mansoni glutamate synthase 0.024 0.0591 0.0591
Brugia malayi Protein kinase domain containing protein 0.0242 0.0602 0.0602
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0107 0.0062 0.0024
Loa Loa (eye worm) hypothetical protein 0.024 0.0591 0.0591
Echinococcus granulosus neurogenic locus notch protein 0.0293 0.0802 0.0767
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0173 0.0326 0.0881
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Schistosoma mansoni myosin-binding protein-related 0.0147 0.0222 0.0222
Echinococcus multilocularis down syndrome cell adhesion 0.0128 0.0148 0.0111
Treponema pallidum NADH oxidase 0.0904 0.3229 1
Loa Loa (eye worm) animal heme peroxidase 0.0219 0.051 0.051
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0282 0.0758 0.2224
Brugia malayi phosphoinositide-dependent protein kinase I 0.0166 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0487 0.1572 0.1572
Schistosoma mansoni titin 0.0128 0.0148 0.0148
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0133 0.0169 0.0377
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0263 0.0682 0.0634
Leishmania major protein kinase, putative 0.0313 0.0884 0.0837
Schistosoma mansoni growth factor receptor-bound protein 0.0125 0.0135 0.0135
Echinococcus multilocularis dual specificity 0.0283 0.0765 0.073
Echinococcus granulosus tyrosine protein kinase HCK 0.0186 0.0378 0.0342
Echinococcus granulosus Immunoglobulin 0.0507 0.1654 0.1622
Echinococcus multilocularis 0.0246 0.0615 0.0579
Schistosoma mansoni hypothetical protein 0.0207 0.0463 0.0463
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0749 0.0749
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Schistosoma mansoni netrin receptor unc5 0.0151 0.0239 0.0239
Plasmodium vivax tyrosine kinase-like protein, putative 0.0166 0.0296 0.0273
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0904 0.3229 0.3213
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0249 0.063 0.0581
Brugia malayi Prion-like- 0.0279 0.0749 0.0749
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.063 0.2142 0.2112
Schistosoma mansoni titin 0.0128 0.0148 0.0148
Onchocerca volvulus 0.0133 0.0169 0.0574
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Loa Loa (eye worm) hypothetical protein 0.0787 0.2765 0.2765
Entamoeba histolytica cell division protein kinase 2, putative 0.0259 0.0669 0.1982
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0283 0.0765 0.0718
Echinococcus multilocularis growth factor receptor bound protein 2 0.0125 0.0135 0.0098
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0472 0.1515 0.1482
Echinococcus granulosus dual specificity 0.0283 0.0765 0.073
Echinococcus multilocularis serine:threonine protein kinase 0.0233 0.0564 0.0528
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0293 0.0802 0.0802
Echinococcus multilocularis 0.0312 0.088 0.0845
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Brugia malayi Hr1 repeat family protein 0.0592 0.1992 0.1992
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0453 0.1438 0.1406
Echinococcus multilocularis N chimaerin 0.0152 0.0244 0.0207
Echinococcus granulosus neurogenic locus notch protein 4 0.0293 0.0802 0.0767
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.0318 0.084
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0313 0.0884 0.0837
Schistosoma mansoni glutamate synthase 0.024 0.0591 0.0591
Brugia malayi Protein kinase domain containing protein 0.0335 0.0968 0.0968
Echinococcus multilocularis hypothetical protein 0.0207 0.0463 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0279 0.0749 0.0749
Echinococcus granulosus casein kinase I alpha 0.0222 0.052 0.0484
Trichomonas vaginalis CAMK family protein kinase 0.0568 0.1894 0.58
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0113 0.0088 0.0088
Echinococcus granulosus serine:threonine protein kinase N2 0.0264 0.0687 0.0652
Echinococcus granulosus serine:threonine protein kinase MARK2 0.044 0.1388 0.1355
Loa Loa (eye worm) AGC/PKG protein kinase 0.0172 0.0323 0.0323
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Trypanosoma cruzi cdc2-related kinase 1 0.0242 0.0602 0.0554
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0311 0.0875 0.084
Schistosoma mansoni hypothetical protein 0.0147 0.0222 0.0222
Brugia malayi notch-like transmembrane receptor 0.0293 0.0802 0.0802
Echinococcus granulosus epidermal growth factor receptor 0.0492 0.1595 0.1563
Schistosoma mansoni serine/threonine protein kinase 0.0551 0.1827 0.1827
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0172 0.0323 0.0273
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1007 0.364 0.3615
Plasmodium falciparum glutathione reductase 0.0904 0.3229 0.3194
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0904 0.3229 1
Echinococcus multilocularis dual specificity 0.0283 0.0765 0.073
Brugia malayi Immunoglobulin domain containing protein 0.0151 0.0239 0.0239
Schistosoma mansoni cell adhesion molecule 0.0151 0.0239 0.0239
Trichomonas vaginalis CAMK family protein kinase 0.0258 0.0663 0.1926
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Brugia malayi RhoGAP domain containing protein 0.0152 0.0244 0.0244
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0227 0.0542 0.0506
Onchocerca volvulus 0.013 0.0153 0.0523
Brugia malayi kettin 0.0128 0.0148 0.0148
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0242 0.0602 0.0602
Echinococcus multilocularis C type lectin domian containing protein 0.0487 0.1572 0.1539
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0904 0.3229 0.2803
Brugia malayi serine/threonine-protein kinase plk-2 0.0551 0.1827 0.1827
Schistosoma mansoni hypothetical protein 0.0128 0.0148 0.0148
Toxoplasma gondii casein kinase I 0.0222 0.052 0.0471
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.024 0.0591 0.0556
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0259 0.0667 0.0667
Loa Loa (eye worm) hypothetical protein 0.0487 0.1572 0.1572
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0602 0.0602
Echinococcus multilocularis tyrosine protein kinase Srms 0.0253 0.0645 0.061
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Echinococcus multilocularis serine:threonine protein kinase N2 0.0264 0.0687 0.0652
Echinococcus multilocularis dual specificity 0.0283 0.0765 0.073
Entamoeba histolytica protein kinase, putative 0.0208 0.0467 0.1333
Onchocerca volvulus 0.0487 0.1572 0.535
Echinococcus granulosus neural cadherin 0.0293 0.0802 0.0767
Loa Loa (eye worm) hypothetical protein 0.0368 0.1099 0.1099
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0222 0.0222
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0128 0.0148 0.0148
Brugia malayi Muscle positioning protein 4 0.0293 0.0802 0.0802
Entamoeba histolytica protein kinase , putative 0.024 0.0592 0.1736
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0313 0.0884 0.0884
Brugia malayi Kinase associated domain 1 family protein 0.0207 0.0463 0.0463
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0358 0.1063 0.1063
Entamoeba histolytica PH domain containing protein kinase, putative 0.0335 0.0969 0.2944
Onchocerca volvulus 0.0291 0.0794 0.2702
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0112 0.0083 0.0083
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0231 0.0555 0.0533
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0367 0.0995
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.024 0.0592 0.1736
Trichomonas vaginalis disulfide oxidoreductase, putative 0.024 0.0591 0.1701
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0176 0.0337 0.03
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0307 0.0857 0.0822
Onchocerca volvulus 0.0293 0.0802 0.2731
Echinococcus granulosus c src tyrosine kinase 0.0191 0.0398 0.0362
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.024 0.0591 0.1694
Onchocerca volvulus 0.0487 0.1572 0.535
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0104 0.0051 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0551 0.1827 0.5588
Trypanosoma brucei protein kinase, putative 0.0188 0.0385 0.0336
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0291 0.0291
Entamoeba histolytica protein kinase, putative 0.0328 0.0943 0.2861
Schistosoma mansoni vesicular amine transporter 0.0507 0.1654 0.1654
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0339 0.0984 0.0984
Trichomonas vaginalis CAMK family protein kinase 0.0551 0.1827 0.5588
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.05 0.1623 0.1623
Schistosoma mansoni vam6/vps39 related 0.0227 0.0542 0.0542
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0206 0.0456 0.0456
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0311 0.0875 0.084
Loa Loa (eye worm) cyclin domain-containing protein 0.0876 0.3119 0.3119
Loa Loa (eye worm) hypothetical protein 0.0182 0.0361 0.0361
Echinococcus multilocularis protein jagged 2 0.0293 0.0802 0.0767
Schistosoma mansoni cell adhesion molecule 0.0298 0.0823 0.0823
Loa Loa (eye worm) cyclin C 0.1751 0.6594 0.6594
Plasmodium vivax calcium-dependent protein kinase, putative 0.0206 0.0456 0.0434
Brugia malayi ephrin receptor 1 precursor 0.0128 0.0146 0.0146
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0107 0.0062 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.044 0.1388 0.1388
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0904 0.3229 0.3194
Onchocerca volvulus 0.013 0.0156 0.0532
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0307 0.0857 0.0822
Brugia malayi Protein kinase domain containing protein 0.0593 0.1994 0.1994
Loa Loa (eye worm) hypothetical protein 0.0291 0.0794 0.0794
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.024 0.0592 0.0556
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.024 0.0591 0.1694
Echinococcus multilocularis cyclin dependent kinase 19 0.1176 0.431 0.4288
Loa Loa (eye worm) TK/KIN16 protein kinase 0.136 0.5044 0.5044
Brugia malayi STE20-like kinase MST 0.0523 0.1718 0.1718
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Leishmania major casein kinase II, putative 0.0204 0.0451 0.0402
Onchocerca volvulus 0.0128 0.0148 0.0505
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0274 0.0274
Trichomonas vaginalis CK1 family protein kinase 0.0222 0.052 0.1475
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0151 0.0239 0.0239
Schistosoma mansoni sulfide quinone reductase 0.024 0.0591 0.0591
Loa Loa (eye worm) AUR protein kinase 0.024 0.0592 0.0592
Brugia malayi Protein kinase domain containing protein 0.017 0.0313 0.0313
Echinococcus granulosus mitogen activated protein kinase 0.0171 0.0318 0.0281
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0152 0.0244 0.0244
Loa Loa (eye worm) AGC/PKA protein kinase 0.0231 0.0555 0.0555
Giardia lamblia Kinase, CMGC CK2 0.0204 0.0451 0.1257
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0107 0.0062 0.0024
Plasmodium falciparum serine/threonine protein kinase 0.017 0.0313 0.0263
Trypanosoma brucei NADH dehydrogenase 0.024 0.0591 0.0543
Brugia malayi Calcium binding EGF domain containing protein 0.0293 0.0802 0.0802
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.0318 0.084
Loa Loa (eye worm) TK/ROR protein kinase 0.0195 0.0412 0.0412
Echinococcus multilocularis myosin iiia 0.0173 0.0326 0.0289
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0718 0.2493 0.2464
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0682 0.1984
Echinococcus granulosus cyclin dependent kinase 19 0.1176 0.431 0.4288
Trypanosoma cruzi casein kinase, putative 0.0222 0.052 0.0471
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0308 0.0861 0.0861
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0274 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0718 0.2493 0.2493
Onchocerca volvulus 0.0487 0.1572 0.535
Entamoeba histolytica protein kinase, putative 0.0176 0.0337 0.0916
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.0409 0.1265 0.1265
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0176 0.0337 0.03
Brugia malayi protein kinase C3,putative 0.0322 0.0916 0.0916
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0444 0.1401 0.1401
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1485 0.5537 0.552
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Schistosoma mansoni cell adhesion molecule 0.0128 0.0148 0.0148
Schistosoma mansoni hypothetical protein 0.0151 0.0239 0.0239
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.058 0.1943 0.1943
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.1438 0.1438
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.024 0.0591 0.0556
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0052 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0367 0.0994
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0667 0.0667
Loa Loa (eye worm) hypothetical protein 0.0233 0.0564 0.0564
Giardia lamblia Kinase, CMGC CDK 0.0242 0.0602 0.1733
Trypanosoma brucei hypothetical protein, conserved 0.024 0.0591 0.0543
Echinococcus granulosus Immunoglobulin subtype 0.0151 0.0239 0.0202
Giardia lamblia Kinase, NEK 0.0278 0.0742 0.2174
Echinococcus granulosus tyrosine protein kinase ABL1 0.0133 0.0169 0.0131
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.024 0.0591 0.1694
Giardia lamblia Kinase, CDC7 0.0183 0.0367 0.0994
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0207 0.0463 0.0463
Trypanosoma brucei SNF1-related protein kinases, putative 0.016 0.0274 0.0224
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0176 0.0337 0.03
Entamoeba histolytica protein kinase, putative 0.0596 0.2005 0.6266
Schistosoma mansoni serine/threonine kinase 0.0328 0.0943 0.0943
Echinococcus multilocularis insulin growth factor binding 0.0128 0.0148 0.0111
Brugia malayi glutamate synthase 0.024 0.0591 0.0591
Onchocerca volvulus 0.0487 0.1572 0.535
Plasmodium vivax ferrodoxin reductase, putative 0.024 0.0591 0.0569
Schistosoma mansoni protein kinase 0.045 0.1428 0.1428
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0313 0.0884 0.0837
Brugia malayi Protein kinase domain containing protein 0.0286 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0611 0.2066 0.2066
Echinococcus multilocularis roundabout 2 0.0298 0.0823 0.0788
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0231 0.0555 0.0507
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0339 0.0984 0.0949
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Echinococcus multilocularis tyrosine protein kinase Abl 0.0191 0.0398 0.0362
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0227 0.0542 0.0542
Echinococcus granulosus Down syndrome cell adhesion molecule 0.017 0.0313 0.0276
Loa Loa (eye worm) hypothetical protein 0.0391 0.1193 0.1193
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0104 0.0052 0.0004
Echinococcus granulosus roundabout 2 0.0298 0.0823 0.0788
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0283 0.0765 0.0765
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0307 0.0857 0.0822
Schistosoma mansoni serine/threonine-protein kinase 0.0335 0.0969 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0497 0.1612 0.1612
Brugia malayi Protein kinase domain containing protein 0.0313 0.0884 0.0884
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0451 0.1257
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0307 0.0857 0.0857
Onchocerca volvulus 0.0133 0.0169 0.0574
Echinococcus granulosus serine:threonine kinase SAD 1 0.016 0.0274 0.0236
Loa Loa (eye worm) AGC/NDR protein kinase 0.0328 0.0943 0.0943
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0249 0.063 0.0581
Entamoeba histolytica cell division protein kinase 2, putative 0.0242 0.0602 0.1766
Loa Loa (eye worm) protein kinase domain-containing protein 0.0435 0.1366 0.1366
Schistosoma mansoni tyrosine kinase 0.037 0.1108 0.1108
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.024 0.0591 0.0556
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0254 0.0649 0.0601
Onchocerca volvulus 0.0636 0.2164 0.7368
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0749 0.0749
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0125 0.0135 0.0135
Echinococcus granulosus slit 2 protein 0.0338 0.0982 0.0947
Echinococcus granulosus insulin growth factor binding 0.0128 0.0148 0.0111
Schistosoma mansoni basigin related 0.0151 0.0239 0.0239
Schistosoma mansoni basigin related 0.0151 0.0239 0.0239
Onchocerca volvulus 0.0133 0.0169 0.0574
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Brugia malayi Protein kinase c protein 2 0.0236 0.0577 0.0577
Echinococcus granulosus neurogenic locus protein delta 0.0293 0.0802 0.0767
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Giardia lamblia Kinase, CMGC GSK 0.0263 0.0682 0.1984
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0173 0.0326 0.0276
Loa Loa (eye worm) AGC/PKN protein kinase 0.0592 0.1992 0.1992
Loa Loa (eye worm) notch protein 0.0293 0.0802 0.0802
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0445 0.1408 0.1375
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0904 0.3229 0.3194
Echinococcus multilocularis mitogen activated protein kinase 14 0.0325 0.0928 0.0893
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0242 0.0602 0.0566
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0367 0.0994
Entamoeba histolytica protein kinase domain containing protein 0.0263 0.0682 0.2022
Brugia malayi Protein kinase domain containing protein 0.0651 0.2224 0.2224
Echinococcus granulosus activin receptor type 0.0134 0.0171 0.0133
Loa Loa (eye worm) hypothetical protein 0.0151 0.0239 0.0239
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0222 0.0222
Schistosoma mansoni septate junction protein 0.0279 0.0749 0.0749
Loa Loa (eye worm) hypothetical protein 0.055 0.1822 0.1822
Echinococcus granulosus delta-like protein 1 0.0293 0.0802 0.0767
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.0171 0.0383
Loa Loa (eye worm) hypothetical protein 0.0231 0.0555 0.0555
Trichomonas vaginalis AGC family protein kinase 0.024 0.0592 0.1703
Loa Loa (eye worm) hypothetical protein 0.0379 0.1145 0.1145
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0249 0.063 0.0581
Giardia lamblia Aurora kinase 0.024 0.0592 0.1703
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0259 0.0667 0.0632
Brugia malayi Tyrosine-protein kinase abl-1 0.0191 0.0398 0.0398
Loa Loa (eye worm) gastrulation defective protein 1 0.1108 0.4041 0.4041
Loa Loa (eye worm) hypothetical protein 0.0151 0.0239 0.0239
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0171 0.0318 0.0268
Echinococcus granulosus cyclin dependent kinase 1 0.0242 0.0602 0.0566
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0393 0.12 0.12
Schistosoma mansoni serine/threonine protein kinase 0.0662 0.2271 0.2271
Entamoeba histolytica hypothetical protein 0.0391 0.1191 0.3657
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0259 0.0667 0.0667
Toxoplasma gondii EGF family domain-containing protein 0.0293 0.0802 0.0755
Loa Loa (eye worm) hypothetical protein 0.0487 0.1572 0.1572
Loa Loa (eye worm) hypothetical protein 0.0128 0.0148 0.0148
Brugia malayi Leucine Rich Repeat family protein 0.0129 0.0151 0.0151
Trypanosoma cruzi casein kinase, putative 0.0222 0.052 0.0471
Brugia malayi cell division control protein 2 homolog 0.0242 0.0602 0.0602
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.016 0.0274 0.0224
Onchocerca volvulus Neurogenic locus notch homolog 0.0293 0.0802 0.2731
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.024 0.0591 0.0543
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0169 0.0169
Echinococcus granulosus tyrosine protein kinase shark 0.0353 0.1041 0.1007
Loa Loa (eye worm) SRC-1 0.0311 0.0875 0.0875
Giardia lamblia Thioredoxin reductase 0.024 0.0591 0.1701
Entamoeba histolytica serine/threonine protein kinase, putative 0.016 0.0274 0.0714
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0134 0.0171 0.012
Loa Loa (eye worm) hypothetical protein 0.0214 0.0489 0.0489
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0765 0.2246
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0239 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.016 0.0274 0.0274
Echinococcus multilocularis calcium activated potassium channel 0.0275 0.0732 0.0696
Loa Loa (eye worm) hypothetical protein 0.0293 0.0802 0.0802
Brugia malayi EGF-like domain containing protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0222 0.052 0.052
Schistosoma mansoni hypothetical protein 0.024 0.0591 0.0591
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Echinococcus multilocularis protein jagged 1 0.0293 0.0802 0.0767
Plasmodium vivax apical sushi protein, putative 0.0487 0.1572 0.1552
Entamoeba histolytica protein kinase, putative 0.017 0.0313 0.084
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0293 0.0802 0.2731
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0147 0.0222 0.0222
Echinococcus multilocularis dual specificity 0.0249 0.063 0.0594
Schistosoma mansoni tyrosine kinase 0.0426 0.1332 0.1332
Echinococcus granulosus casein kinase i 0.0222 0.052 0.0484
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0487 0.1572 0.1572
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0233 0.0564 0.0564
Echinococcus granulosus dual specificity protein kinase clk2 0.0313 0.0884 0.0849
Echinococcus granulosus tyrosine protein kinase Src42A 0.0189 0.039 0.0354
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0231 0.0555 0.0507
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0164 0.0291 0.0291
Schistosoma mansoni slit 0.0129 0.0151 0.0151
Echinococcus granulosus Protein kinase C brain isozyme 0.0497 0.1612 0.158
Leishmania major protein kinase A catalytic subunit isoform 2 0.0231 0.0555 0.0507
Echinococcus granulosus cGMP dependent protein kinase 0.0172 0.0323 0.0286
Brugia malayi Calcium binding EGF domain containing protein 0.0293 0.0802 0.0802
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0134 0.0171 0.012
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0651 0.2224 0.2224
Schistosoma mansoni basigin related 0.0151 0.0239 0.0239
Trichomonas vaginalis STE family protein kinase 0.0173 0.0326 0.0864
Brugia malayi MAP kinase sur-1 0.0171 0.0318 0.0318
Echinococcus multilocularis neural cadherin 0.0293 0.0802 0.0767
Trichomonas vaginalis CAMK family protein kinase 0.0258 0.0663 0.1926
Mycobacterium ulcerans monoxygenase 0.024 0.0591 0.1694
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0279 0.0749 0.255
Trypanosoma brucei protein kinase, putative 0.0134 0.0171 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0367 0.0367
Onchocerca volvulus 0.0222 0.052 0.1769
Echinococcus multilocularis casein kinase I delta 0.0222 0.052 0.0484
Leishmania major protein kinase, putative 0.0173 0.0326 0.0276
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.024 0.0591 0.0543
Loa Loa (eye worm) one IG domain family member 0.0128 0.0148 0.0148
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0222 0.052 0.052
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0171 0.0318 0.0268
Trichomonas vaginalis CK1 family protein kinase 0.0222 0.052 0.1475
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0241 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0385 0.0385
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.024 0.0591 0.1701
Brugia malayi hypothetical protein 0.0133 0.0169 0.0169
Schistosoma mansoni hemicentin 0.0147 0.0222 0.0222
Echinococcus granulosus expressed protein 0.017 0.0313 0.0276
Brugia malayi Protein kinase domain containing protein 0.0651 0.2224 0.2224
Loa Loa (eye worm) hypothetical protein 0.0487 0.1572 0.1572
Echinococcus granulosus insulin growth factor 1 receptor beta 0.063 0.2142 0.2112
Schistosoma mansoni glutamate synthase 0.024 0.0591 0.0591
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0539 0.1778 0.1778
Echinococcus granulosus serine:threonine protein kinase N2 0.0592 0.1992 0.1961
Entamoeba histolytica protein kinase domain containing protein 0.0413 0.128 0.3941
Onchocerca volvulus 0.0487 0.1572 0.535
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0682 0.1984
Schistosoma mansoni hypothetical protein 0.0151 0.0239 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0413 0.128 0.128
Brugia malayi serine/threonine-protein kinase PAK 7 0.0473 0.1518 0.1518
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.024 0.0591 0.0556
Schistosoma mansoni hypothetical protein 0.0128 0.0148 0.0148
Echinococcus granulosus dual specificity testis-specific protein kinase 0.045 0.1428 0.1396
Loa Loa (eye worm) hypothetical protein 0.0283 0.0761 0.0761
Brugia malayi Cadherin domain containing protein 0.0293 0.0802 0.0802
Brugia malayi casein kinase I 0.0222 0.052 0.052
Brugia malayi Protein kinase domain containing protein 0.1918 0.726 0.726
Echinococcus granulosus epidermal growth factor receptor 0.0706 0.2446 0.2417
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.024 0.0591 0.0591
Entamoeba histolytica protein kinase, putative 0.0147 0.0222 0.055
Echinococcus multilocularis NCK adaptor protein 0.0127 0.0143 0.0106
Schistosoma mansoni peroxidasin 0.0243 0.0603 0.0603
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0195 0.0412 0.0375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Schistosoma mansoni notch 0.0293 0.0802 0.0802
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0479 0.1542 0.1509
Echinococcus granulosus casein kinase I alpha 0.0222 0.052 0.0484
Trypanosoma cruzi polo-like protein kinase, putative 0.0551 0.1827 0.1785
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0222 0.0222
Trypanosoma brucei casein kinase I, isoform 2 0.0222 0.052 0.0471
Leishmania major hypothetical protein, conserved 0.024 0.0591 0.0543
Brugia malayi SH2 domain containing protein 0.0133 0.0169 0.0169
Giardia lamblia Kinase, CMGC CLK 0.0313 0.0884 0.262
Trypanosoma cruzi hypothetical protein, conserved 0.024 0.0591 0.0543
Schistosoma mansoni c4b-binding protein beta chain 0.0487 0.1572 0.1572
Loa Loa (eye worm) hypothetical protein 0.0487 0.1572 0.1572
Entamoeba histolytica protein kinase, putative 0.0132 0.0161 0.0353
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0274 0.07
Echinococcus multilocularis serine:threonine protein kinase 38 0.0328 0.0943 0.0908
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0718 0.2493 0.2464
Entamoeba histolytica PH domain containing protein kinase, putative 0.0246 0.0616 0.1813
Trichomonas vaginalis AGC family protein kinase 0.0349 0.1027 0.307
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0154 0.0251 0.0201
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0206 0.0456 0.042
Entamoeba histolytica protein kinase, putative 0.058 0.1943 0.607
Echinococcus granulosus tyrosine protein kinase Src64B 0.0311 0.0875 0.084
Brugia malayi Cyclin C 0.1751 0.6594 0.6594
Echinococcus multilocularis mitogen activated protein kinase 0.0171 0.0318 0.0281
Leishmania major protein kinase, putative 0.0313 0.0884 0.0837
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0148 0.0148
Onchocerca volvulus Putative cubilin 0.0293 0.0802 0.2731
Schistosoma mansoni cell polarity protein 0.0293 0.0802 0.0802
Loa Loa (eye worm) TK protein kinase 0.0498 0.1618 0.1618
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0151 0.0239 0.0239
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0163 0.0286 0.0249
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0339 0.0984 0.0984
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0206 0.0456 0.0434
Echinococcus granulosus neuroglian 0.0298 0.0823 0.0788
Schistosoma mansoni nephrin 0.0298 0.0823 0.0823
Onchocerca volvulus 0.0376 0.1132 0.3854
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0311 0.0875 0.084
Loa Loa (eye worm) hypothetical protein 0.0151 0.0239 0.0239
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0227 0.0542 0.0494
Echinococcus multilocularis protein kinase c epsilon type 0.0416 0.1292 0.1258
Echinococcus multilocularis tyrosine protein kinase Blk 0.0253 0.0645 0.061
Echinococcus granulosus titin 0.0128 0.0148 0.0111
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0328 0.0943 0.0908
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0151 0.0239 0.0202

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) > 1000 nM Binding Affinity towards Rat Androgen Receptor was determined using [3H]- mibolerone as radioligand. ChEMBL. 10691684

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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