Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.3709 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.3709 | 0.5 |
Brugia malayi | hypothetical protein | 0.0028 | 0.4456 | 0.4456 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.4456 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.4456 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.3709 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.3709 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.3709 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.4456 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.3709 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.3709 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3709 | 0.3221 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0719 | 0.139 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.4456 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.3709 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3709 | 0.3221 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.3709 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4456 | 0.4026 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.3709 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.4456 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.3709 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.3709 | 0.3709 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.4456 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3709 | 0.3221 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0719 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.3709 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.3709 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.3709 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.3709 | 0.3709 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.4456 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.3709 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.4456 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.3709 | 0.3709 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.