Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | arginine vasopressin receptor 1B | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.9702 | 1 |
Entamoeba histolytica | cyclin, putative | 0.0035 | 0.2023 | 0.9087 |
Echinococcus granulosus | cyclins | 0.0035 | 0.2023 | 0.2085 |
Trichomonas vaginalis | cyclins, putative | 0.0035 | 0.2023 | 0.8134 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2023 | 0.2023 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.2226 | 1 |
Echinococcus multilocularis | cyclins | 0.0035 | 0.2023 | 0.2023 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.2226 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0041 | 0.2487 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0035 | 0.2023 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0041 | 0.2487 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0035 | 0.2023 | 1 |
Trichomonas vaginalis | cyclin B3, putative | 0.0035 | 0.2023 | 0.8134 |
Echinococcus granulosus | cyclin B3 1 | 0.0035 | 0.2023 | 0.2085 |
Echinococcus granulosus | cyclins | 0.0035 | 0.2023 | 0.2085 |
Echinococcus multilocularis | cyclins | 0.0035 | 0.2023 | 0.2023 |
Trichomonas vaginalis | cyclin A, putative | 0.0035 | 0.2023 | 0.8134 |
Brugia malayi | RNA binding protein | 0.0062 | 0.4008 | 0.4008 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4008 | 0.4008 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.4008 | 0.4008 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.4008 | 0.4008 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4008 | 0.4008 |
Schistosoma mansoni | cyclin B | 0.0035 | 0.2023 | 0.2023 |
Entamoeba histolytica | cyclin family protein | 0.0035 | 0.2023 | 0.9087 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0041 | 0.2487 | 0.2563 |
Trichomonas vaginalis | cyclin B, putative | 0.0035 | 0.2023 | 0.8134 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0035 | 0.2023 | 0.9087 |
Echinococcus granulosus | cyclins | 0.0035 | 0.2023 | 0.2085 |
Schistosoma mansoni | cyclin B3 | 0.0035 | 0.2023 | 0.2023 |
Trypanosoma cruzi | cyclin, putative | 0.0035 | 0.2023 | 1 |
Echinococcus multilocularis | cyclins | 0.0035 | 0.2023 | 0.2023 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4008 | 0.4008 |
Trichomonas vaginalis | cyclin D, putative | 0.0035 | 0.2023 | 0.8134 |
Echinococcus granulosus | cyclins | 0.0035 | 0.2023 | 0.2085 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0041 | 0.2487 | 1 |
Leishmania major | cyclin | 0.0035 | 0.2023 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0035 | 0.2023 | 0.2023 |
Echinococcus multilocularis | cyclins | 0.0035 | 0.2023 | 0.2023 |
Echinococcus multilocularis | cyclins | 0.0035 | 0.2023 | 0.2023 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0035 | 0.2023 | 0.2023 |
Trichomonas vaginalis | cyclin B, putative | 0.0035 | 0.2023 | 0.8134 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0041 | 0.2487 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0035 | 0.2023 | 0.8134 |
Echinococcus granulosus | cyclin B | 0.0035 | 0.2023 | 0.2085 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0035 | 0.2023 | 0.2023 |
Echinococcus multilocularis | cyclin B | 0.0035 | 0.2023 | 0.2023 |
Giardia lamblia | Hypothetical protein | 0.0035 | 0.2023 | 0.9087 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0035 | 0.2023 | 0.2023 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.1379 | 0.5547 |
Trichomonas vaginalis | cyclin B, putative | 0.0035 | 0.2023 | 0.8134 |
Giardia lamblia | Cyclin A | 0.0035 | 0.2023 | 0.9087 |
Trichomonas vaginalis | cyclins, putative | 0.0035 | 0.2023 | 0.8134 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.2226 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0035 | 0.2023 | 0.8134 |
Echinococcus multilocularis | cyclin b3 | 0.0035 | 0.2023 | 0.2023 |
Entamoeba histolytica | cyclin family protein | 0.0035 | 0.2023 | 0.9087 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.4008 | 0.4008 |
Onchocerca volvulus | 0.0035 | 0.2023 | 1 | |
Trichomonas vaginalis | cyclins, putative | 0.0035 | 0.2023 | 0.8134 |
Schistosoma mansoni | cyclins | 0.0035 | 0.2023 | 0.2023 |
Echinococcus multilocularis | cyclins | 0.0035 | 0.2023 | 0.2023 |
Echinococcus granulosus | cyclin b3 | 0.0035 | 0.2023 | 0.2085 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0035 | 0.2023 | 1 |
Echinococcus multilocularis | cyclin B3 1 | 0.0035 | 0.2023 | 0.2023 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.4008 | 0.4008 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0035 | 0.2023 | 1 |
Plasmodium falciparum | cyclin | 0.0035 | 0.2023 | 0.9087 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4008 | 0.4008 |
Echinococcus multilocularis | cyclins | 0.0035 | 0.2023 | 0.2023 |
Trichomonas vaginalis | cyclin B, putative | 0.0035 | 0.2023 | 0.8134 |
Trichomonas vaginalis | cyclins, putative | 0.0035 | 0.2023 | 0.8134 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4008 | 0.4008 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.4008 | 0.4008 |
Trypanosoma cruzi | cyclin 6, putative | 0.0035 | 0.2023 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2023 | 0.2023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.2023 | 0.8134 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0035 | 0.2023 | 0.2023 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0041 | 0.2487 | 1 |
Echinococcus granulosus | cyclins | 0.0035 | 0.2023 | 0.2085 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0035 | 0.2023 | 0.2085 |
Entamoeba histolytica | cyclin, putative | 0.0035 | 0.2023 | 0.9087 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.4008 | 0.4008 |
Trichomonas vaginalis | cyclin D, putative | 0.0035 | 0.2023 | 0.8134 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.4008 | 0.4132 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | > 10 uM | Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cells | ChEMBL. | 21601454 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.