Detailed information for compound 1517572

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 374.497 | Formula: C20H26N2O3S
  • H donors: 1 H acceptors: 3 LogP: 0.67 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC[C@@H]1c2cn(Cc3ccccc3)c(=O)cc2CN1S(=O)C(C)(C)C
  • InChi: 1S/C20H26N2O3S/c1-20(2,3)26(25)22-13-16-11-19(24)21(12-15-7-5-4-6-8-15)14-17(16)18(22)9-10-23/h4-8,11,14,18,23H,9-10,12-13H2,1-3H3/t18-,26?/m1/s1
  • InChiKey: GAOOXLBLYIYKGW-QOBPCVTDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Schistosoma mansoni hypothetical protein 0.0065 0.0094 0.0251
Loa Loa (eye worm) tubulin alpha-3 chain 0.0734 0.1387 0.4388
Trichomonas vaginalis penicillin-binding protein, putative 0.0191 0.0337 0.1065
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0051 0.0133
Loa Loa (eye worm) CXXC zinc finger family protein 0.0118 0.0197 0.062
Loa Loa (eye worm) glutaminase 0.028 0.051 0.161
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0059
Echinococcus granulosus fibroblast growth factor receptor 4 0.0117 0.0194 0.0516
Trypanosoma brucei epsilon tubulin 0.0979 0.186 0.5885
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.0125
Loa Loa (eye worm) beta-lactamase 0.0191 0.0337 0.1065
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0335 0.1057
Trypanosoma cruzi MFS transporter, putative 0.0062 0.0088 0.0277
Echinococcus granulosus tm gpcr rhodopsin 0.059 0.1109 0.2965
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.003 0.0095
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0065 0.0173
Toxoplasma gondii protease inhibitor PI2 0.0042 0.005 0.016
Onchocerca volvulus 0.0071 0.0106 0.1088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Brugia malayi Tubulin beta chain 0.0419 0.0779 0.2463
Brugia malayi hypoxia-induced factor 1 0.0167 0.0292 0.0921
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0048 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0206
Leishmania major cathepsin L-like protease 0.0019 0.0005 0.0011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.008 0.0123 0.0329
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0166 0.029 0.0289
Schistosoma mansoni tyrosine kinase 0.0022 0.0011 0.0029
Schistosoma mansoni chromobox protein 0.0072 0.0109 0.0291
Echinococcus multilocularis cpg binding protein 0.0125 0.021 0.0209
Schistosoma mansoni ferritin light chain 0.0027 0.002 0.0054
Echinococcus granulosus tubulin alpha chain 0.1237 0.2358 0.6308
Echinococcus granulosus GPCR family 2 0.0065 0.0094 0.0248
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0066 0.0174
Brugia malayi Tubulin beta-1 chain 0.1652 0.316 1
Brugia malayi eukaryotic initiation factor 4A 0.0027 0.0021 0.0064
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0061 0.0192
Echinococcus multilocularis epidermal growth factor receptor 0.0262 0.0474 0.0473
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0021 0.0055
Loa Loa (eye worm) tubulin beta chain 0.0419 0.0779 0.2463
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0018
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0419 0.0779 0.2463
Trichomonas vaginalis tubulin, putative 0.0503 0.094 0.2972
Plasmodium vivax tubulin alpha chain, putative 0.1237 0.2358 0.746
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0025 0.0024
Toxoplasma gondii beta-tubulin, putative 0.1652 0.316 1
Echinococcus granulosus Tubulin alpha 1 chain 0.1237 0.2358 0.6308
Loa Loa (eye worm) cysteine protease 0.0019 0.0005 0.0011
Echinococcus granulosus peroxisome assembly protein 26 0.1237 0.2358 0.6308
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.0354 0.0353
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0021 0.0064
Leishmania major gamma-tubulin 0.098 0.1861 0.589
Loa Loa (eye worm) BEN-1 protein 0.1652 0.316 1
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0005 0.0012
Brugia malayi isocitrate dehydrogenase 0.0166 0.029 0.0914
Brugia malayi acetyltransferase, GNAT family protein 0.0162 0.0282 0.0889
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0036 0.011
Plasmodium vivax vivapain-2 0.0019 0.0005 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0066 0.0177
Echinococcus granulosus smad 0.0035 0.0036 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Treponema pallidum NADH oxidase 0.0018 0.0004 0.0049
Echinococcus multilocularis isocitrate dehydrogenase 0.0166 0.029 0.0289
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0066 0.0206
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0289 0.0527 0.1665
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0151 0.0261 0.0695
Loa Loa (eye worm) BEN-1 protein 0.1652 0.316 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0071 0.0106 0.0333
Loa Loa (eye worm) glutathione reductase 0.0053 0.007 0.0219
Echinococcus multilocularis thyroid hormone receptor alpha 0.0291 0.0531 0.053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0151 0.0261 0.0822
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Toxoplasma gondii isocitrate dehydrogenase 0.0166 0.029 0.0917
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0073 0.0194
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0007 0.0018
Echinococcus multilocularis nuclear receptor nhr 48 0.0071 0.0106 0.0105
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0062 0.0088 0.0087
Brugia malayi CHE-14 protein 0.0353 0.0651 0.2057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0021 0.0062
Leishmania major beta tubulin 0.1652 0.316 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0123 0.0386
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0005 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0191 0.0337 0.1065
Loa Loa (eye worm) hypothetical protein 0.014 0.0239 0.0753
Echinococcus granulosus tubulin alpha chain 0.1237 0.2358 0.6308
Schistosoma mansoni nuclear receptor 0.0071 0.0106 0.0285
Entamoeba histolytica protein kinase, putative 0.0039 0.0045 0.0142
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0047 0.0455
Leishmania major beta tubulin 0.1652 0.316 1
Brugia malayi CHD4 protein 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0277
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0166 0.029 0.0289
Trypanosoma brucei trypanothione reductase 0.0053 0.007 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0151 0.0261 0.0822
Echinococcus multilocularis tyrosine protein kinase Srms 0.0047 0.0059 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Brugia malayi hypothetical protein 0.0263 0.0477 0.1506
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0151 0.0261 0.2737
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0191 0.0337 0.0902
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0151 0.0261 0.0822
Leishmania major beta tubulin 0.1652 0.316 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0151 0.0261 0.0822
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0151 0.0261 0.0822
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0001 0.0004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1219 0.2324 1
Schistosoma mansoni cpg binding protein 0.0125 0.021 0.0562
Entamoeba histolytica hypothetical protein 0.008 0.0124 0.0391
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0078 0.0243
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.011 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0007 0.0015
Loa Loa (eye worm) alpha-tubulin 0.1237 0.2358 0.7463
Brugia malayi Cytochrome P450 family protein 0.0026 0.0019 0.0056
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0066 0.0206
Schistosoma mansoni nuclear receptor 0.0071 0.0106 0.0285
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.005 0.0065 0.0203
Mycobacterium tuberculosis Probable reductase 0.012 0.02 0.0847
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Schistosoma mansoni tyrosine kinase 0.0236 0.0425 0.1138
Entamoeba histolytica tubulin family protein 0.1652 0.316 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0007 0.0018
Brugia malayi sulfakinin receptor protein 0.0251 0.0453 0.1431
Schistosoma mansoni ap endonuclease 0.002 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Trypanosoma brucei beta tubulin 0.1652 0.316 1
Brugia malayi nuclear receptor RXR 0.0071 0.0106 0.0333
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0045 0.0141
Onchocerca volvulus 0.0191 0.0337 0.3557
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0043 0.0134
Trichomonas vaginalis tubulin beta chain, putative 0.1652 0.316 1
Echinococcus multilocularis cysteine protease 0.0019 0.0005 0.0004
Echinococcus granulosus epidermal growth factor receptor 0.0483 0.0903 0.2413
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.004 0.0128
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0106 0.0105
Entamoeba histolytica hypothetical protein 0.008 0.0124 0.0391
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0117 0.0194 0.0193
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Entamoeba histolytica recQ family helicase, putative 0.0035 0.0036 0.0113
Echinococcus granulosus integrin alpha ps 0.0076 0.0116 0.0307
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.002 0.0059
Brugia malayi secreted modular calcium-binding protein 1 0.0042 0.005 0.0156
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0161 0.0279 0.0278
Brugia malayi conserved hypotetical protein 0.0071 0.0106 0.0333
Schistosoma mansoni patched 1 0.0353 0.0651 0.1741
Echinococcus granulosus thyroid hormone receptor alpha 0.0071 0.0106 0.0282
Brugia malayi beta-tubulin, identical 0.1652 0.316 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0191 0.0337 0.1065
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0032 0.003 0.0078
Trypanosoma cruzi zeta tubulin, putative 0.1014 0.1929 0.6102
Loa Loa (eye worm) nuclear receptor NHR-67 0.0071 0.0106 0.0333
Brugia malayi ecdysteroid receptor 0.0151 0.0261 0.0822
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.002 0.0161
Onchocerca volvulus 0.0457 0.0851 0.9047
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0073 0.0194
Echinococcus multilocularis Tubulin alpha 1 chain 0.1237 0.2358 0.2357
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0151 0.0261 0.0822
Brugia malayi Patched related family protein 10 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.011 0.0346
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0023 0.0014 0.0036
Echinococcus granulosus cathepsin l1 0.0019 0.0005 0.001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.002 0.0062
Brugia malayi Nuclear hormone receptor-like 1 0.0151 0.0261 0.0822
Echinococcus multilocularis GPCR, family 2 0.0065 0.0094 0.0093
Giardia lamblia Epsilon tubulin 0.0476 0.0889 0.2804
Brugia malayi tubulin alpha chain - mouse 0.1237 0.2358 0.7463
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0265 0.0481 0.1512
Schistosoma mansoni tubulin subunit beta 0.1652 0.316 0.8454
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0025 0.0024
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.002 0.0008 0.0021
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0191 0.0337 0.1437
Schistosoma mansoni nephrin 0.003 0.0026 0.007
Giardia lamblia Beta tubulin 0.1652 0.316 1
Schistosoma mansoni hypothetical protein 0.014 0.0239 0.0639
Echinococcus granulosus tyrosine protein kinase ABL1 0.0244 0.044 0.1174
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.002 0.0008 0.0049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0043 0.0134
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0004 0.0009
Brugia malayi Tubulin alpha-2 chain 0.1237 0.2358 0.7463
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0048 0.0047
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0057 0.0177
Toxoplasma gondii beta tubulin 0.1652 0.316 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0043 0.0134
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0073 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0123 0.0386
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.005 0.0065 0.0206
Trypanosoma cruzi epsilon tubulin, putative 0.0979 0.186 0.5885
Schistosoma mansoni ferritin 0.0027 0.002 0.0054
Trypanosoma cruzi epsilon tubulin, putative 0.0979 0.186 0.5885
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0075 0.0114 0.0349
Schistosoma mansoni tubulin subunit alpha 0.0419 0.0779 0.2084
Brugia malayi Probable isocitrate dehydrogenase 0.002 0.0008 0.0021
Echinococcus granulosus Niemann Pick C1 protein 0.1176 0.224 0.5992
Brugia malayi Protein kinase domain containing protein 0.0157 0.0273 0.086
Echinococcus granulosus Tubulin alpha 1 chain 0.1237 0.2358 0.6308
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0046 0.0045
Echinococcus multilocularis musashi 0.003 0.0027 0.0026
Brugia malayi mbt repeat family protein 0.005 0.0065 0.0201
Brugia malayi MH1 domain containing protein 0.0035 0.0036 0.0112
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0023 0.0014 0.0013
Leishmania major cathepsin L-like protease 0.0019 0.0005 0.0011
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0036 0.0035
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Trichomonas vaginalis tubulin epsilon chain, putative 0.1652 0.316 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi Fibronectin type III domain containing protein 0.0026 0.002 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0151 0.0261 0.0695
Echinococcus multilocularis peroxisome assembly protein 26 0.1237 0.2358 0.2357
Echinococcus multilocularis tubulin epsilon chain 0.0979 0.186 0.1859
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0094 0.0294
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.002 0.0008 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0021 0.0062
Schistosoma mansoni hypothetical protein 0.034 0.0626 0.1675
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0025 0.0065
Brugia malayi tailless protein 0.0071 0.0106 0.0333
Echinococcus multilocularis lamin 0.003 0.0027 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0246 0.0245
Echinococcus multilocularis protein dispatched 1 0.0403 0.0747 0.0746
Mycobacterium tuberculosis Putative ferredoxin reductase 0.012 0.02 0.0847
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.007 0.0185
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0066 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Echinococcus multilocularis survival motor neuron protein 1 0.0263 0.0477 0.0476
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0019 0.0005 0.0012
Loa Loa (eye worm) agrin synaptic family protein 0.0042 0.005 0.0156
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0106 0.0282
Trypanosoma cruzi alpha tubulin, putative 0.1237 0.2358 0.7463
Brugia malayi glutaminase DH11.1 0.028 0.051 0.161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.002 0.0008 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.002 0.0203
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.008 0.0123 0.0326
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0004 0.001
Trichomonas vaginalis tubulin beta chain, putative 0.1237 0.2358 0.7463
Loa Loa (eye worm) intermediate filament protein 0.003 0.0027 0.0081
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.005 0.0065 0.0203
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.011 0.0346
Loa Loa (eye worm) MH2 domain-containing protein 0.0515 0.0964 0.305
Brugia malayi beta-lactamase 0.0191 0.0337 0.1065
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0244 0.044 0.0439
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0268 0.0486 0.1535
Loa Loa (eye worm) hypothetical protein 0.0148 0.0254 0.0801
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0073 0.0072
Mycobacterium tuberculosis Probable dehydrogenase 0.012 0.02 0.0847
Loa Loa (eye worm) TK protein kinase 0.012 0.02 0.0631
Schistosoma mansoni nuclear receptor nhr-48 0.0071 0.0106 0.0285
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0106 0.0282
Echinococcus multilocularis tubulin alpha 3 chain 0.1237 0.2358 0.2357
Schistosoma mansoni isocitrate dehydrogenase 0.002 0.0008 0.0021
Brugia malayi hypothetical protein 0.008 0.0123 0.0386
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.005 0.016
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0268 0.0486 0.13
Loa Loa (eye worm) TK protein kinase 0.0039 0.0045 0.0138
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0073 0.0072
Echinococcus granulosus tyrosine protein kinase Lyn 0.0055 0.0074 0.0196
Echinococcus granulosus tubulin alpha 3 chain 0.1237 0.2358 0.6308
Toxoplasma gondii patched family protein 0.005 0.0065 0.0206
Schistosoma mansoni alpha tubulin 0.1237 0.2358 0.6309
Echinococcus granulosus beta tubulin 0.1652 0.316 0.8453
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0026 0.008
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0048 0.0149
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0061 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.0125
Echinococcus multilocularis neuroglian 0.0027 0.002 0.0019
Echinococcus granulosus isocitrate dehydrogenase NAD 0.002 0.0008 0.0018
Schistosoma mansoni ferritin light chain 0.0027 0.002 0.0054
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.005 0.0156
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0121
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0094 0.0093
Schistosoma mansoni cell adhesion molecule 0.003 0.0026 0.007
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0066 0.0206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0003
Trichomonas vaginalis tubulin epsilon chain, putative 0.1237 0.2358 0.7463
Schistosoma mansoni intermediate filament proteins 0.003 0.0027 0.0071
Brugia malayi Tyrosine-protein kinase abl-1 0.0142 0.0242 0.0764
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0106 0.0331
Schistosoma mansoni apoferritin-2 0.0027 0.002 0.0054
Loa Loa (eye worm) tubulin alpha 2 0.0817 0.1548 0.4898
Loa Loa (eye worm) hypothetical protein 0.0432 0.0804 0.2542
Trichomonas vaginalis conserved hypothetical protein 0.0419 0.0779 0.2463
Echinococcus multilocularis tubulin subunit TubB 0.1237 0.2358 0.2357
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0151 0.0261 0.0697
Leishmania major beta tubulin 0.1652 0.316 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0191 0.0337 0.1065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.002 0.0068
Trypanosoma brucei protein kinase, putative 0.005 0.0066 0.0206
Trypanosoma brucei PAB1-binding protein , putative 0.0265 0.0481 0.152
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0109 0.0341
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0043 0.0134
Schistosoma mansoni tubulin subunit beta 0.1652 0.316 0.8454
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0109 0.0341
Echinococcus granulosus single minded 2 0.004 0.0046 0.012
Onchocerca volvulus 0.003 0.0027 0.0235
Leishmania major beta tubulin 0.1652 0.316 1
Brugia malayi Integrin beta pat-3 precursor 0.0348 0.0641 0.2028
Loa Loa (eye worm) isocitrate dehydrogenase 0.0166 0.029 0.0914
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi Heterochromatin protein 1 0.0072 0.0109 0.0341
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0048 0.0047
Schistosoma mansoni tubulin subunit beta 0.0419 0.0779 0.2084
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0048 0.0126
Echinococcus granulosus neuropeptide receptor A26 0.0526 0.0985 0.2634
Brugia malayi Furin-like cysteine rich region family protein 0.0483 0.0903 0.2854
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.0036 0.011
Schistosoma mansoni integrin beta subunit 0.0205 0.0365 0.0976
Brugia malayi protein-tyrosine kinase 0.0047 0.0059 0.0184
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0061 0.0189
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Trichomonas vaginalis tubulin beta chain, putative 0.1237 0.2358 0.7463
Onchocerca volvulus Putative organic anion transporter 0.0062 0.0088 0.0896
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0092 0.0288
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0007 0.0012
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0019 0.0056
Echinococcus granulosus Solute carrier organic anion transporter family 0.0062 0.0088 0.0234
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Toxoplasma gondii LsmAD domain-containing protein 0.0265 0.0481 0.1523
Echinococcus multilocularis Tubulin alpha 1 chain 0.1237 0.2358 0.2357
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0261 0.0472 0.1261
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Toxoplasma gondii histone lysine methyltransferase SET1 0.0228 0.0409 0.1294
Brugia malayi Tyrosine-protein kinase abl-1 0.011 0.018 0.0567
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0005 0.0011
Trichomonas vaginalis tubulin, putative 0.0477 0.089 0.2815
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0021 0.0063
Onchocerca volvulus 0.0268 0.0486 0.5146
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0078 0.0205
Leishmania major phosphopantetheinyl transferase-like protein 0.0075 0.0114 0.0358
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0277
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.0337 0.1065
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0133 0.0226 0.0958
Onchocerca volvulus Glucosylceramidase homolog 0.019 0.0335 0.3531
Trichomonas vaginalis tubulin gamma chain, putative 0.1652 0.316 1
Brugia malayi hypothetical protein 0.0026 0.002 0.0059
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi nuclear hormone receptor 0.0151 0.0261 0.0822
Loa Loa (eye worm) hypothetical protein 0.0055 0.0075 0.0234
Onchocerca volvulus 0.0151 0.0261 0.2737
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0106 0.0331
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0066 0.0206
Toxoplasma gondii patched family protein 0.005 0.0065 0.0206
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0019 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0335 0.1057
Entamoeba histolytica tubulin family protein 0.1652 0.316 1
Echinococcus multilocularis expressed protein 0.0027 0.002 0.0019
Plasmodium vivax tubulin epsilon chain, putative 0.0979 0.186 0.5881
Trypanosoma brucei beta tubulin 0.1652 0.316 1
Echinococcus multilocularis Tubulin beta 2C chain 0.1652 0.316 0.3159
Onchocerca volvulus 0.0062 0.0088 0.0896
Trypanosoma brucei epsilon tubulin 0.0979 0.186 0.5885
Echinococcus multilocularis Immunoglobulin 0.0023 0.0014 0.0013
Loa Loa (eye worm) nuclear hormone receptor 0.0071 0.0106 0.0333
Leishmania major beta tubulin 0.1652 0.316 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0166 0.029 0.0773
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0066 0.0197
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0078 0.0208
Leishmania major beta tubulin 0.1652 0.316 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0073 0.0194
Echinococcus multilocularis Tubulin beta 2C chain 0.1652 0.316 0.3159
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Echinococcus multilocularis tubulin alpha chain 0.1237 0.2358 0.2357
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0151 0.0261 0.0822
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0038 0.0118
Schistosoma mansoni ap endonuclease 0.002 0.0007 0.0018
Echinococcus multilocularis tubulin alpha chain 0.1237 0.2358 0.2357
Echinococcus multilocularis tubulin alpha chain 0.1237 0.2358 0.2357
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0005 0.0004
Brugia malayi Integrin alpha pat-2 precursor 0.017 0.0297 0.0937
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0018
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0066 0.0174
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Plasmodium vivax glutathione reductase, putative 0.0053 0.007 0.021
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0004 0.0009
Loa Loa (eye worm) tubulin beta-2A chain 0.1652 0.316 1
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0106 0.0333
Echinococcus granulosus tubulin alpha chain 0.1237 0.2358 0.6308
Echinococcus multilocularis tyrosine protein kinase Abl 0.011 0.018 0.0179
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0005 0.0002
Onchocerca volvulus 0.0191 0.0337 0.3557
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0775 0.1467 0.4642
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Trypanosoma cruzi zeta tubulin, putative 0.1014 0.1929 0.6102
Schistosoma mansoni nuclear hormone receptor 0.0151 0.0261 0.0697
Trypanosoma brucei zeta tubulin 0.1014 0.1929 0.6102
Echinococcus granulosus eukaryotic initiation factor 4A 0.0027 0.0021 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0151 0.0261 0.0822
Onchocerca volvulus 0.0042 0.005 0.049
Brugia malayi Tubulin gamma chain 0.098 0.1861 0.589
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0353 0.0651 0.2057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0031 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Loa Loa (eye worm) TK/INSR protein kinase 0.0157 0.0273 0.086
Plasmodium vivax tubulin beta chain, putative 0.1652 0.316 1
Schistosoma mansoni integrin alpha-ps 0.004 0.0045 0.0121
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.005 0.0156
Schistosoma mansoni chromobox protein 0.0072 0.0109 0.0291
Echinococcus multilocularis muscleblind protein 1 0.0148 0.0254 0.0253
Leishmania major beta tubulin 0.1652 0.316 1
Brugia malayi nuclear receptor NHR-88 0.0151 0.0261 0.0822
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0151 0.0261 0.0822
Plasmodium vivax tubulin gamma chain, putative 0.098 0.1861 0.5886
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0036 0.0112
Echinococcus multilocularis Tubulin beta 2C chain 0.1652 0.316 0.3159
Echinococcus granulosus beta LACTamase domain containing family member 0.0191 0.0337 0.09
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0014 0.0042
Giardia lamblia Alpha-tubulin 0.1237 0.2358 0.746
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.011 0.035
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.002 0.0258
Echinococcus granulosus tyrosine kinase 0.0047 0.0059 0.0156
Onchocerca volvulus 0.005 0.0065 0.0646
Brugia malayi Isocitrate dehydrogenase 0.0166 0.029 0.0914
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0262 0.0474 0.1266
Onchocerca volvulus 0.0054 0.0072 0.0723
Brugia malayi hypothetical protein 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Schistosoma mansoni ferritin 0.0027 0.002 0.0054
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0075 0.0114 0.0361
Schistosoma mansoni hypothetical protein 0.034 0.0626 0.1675
Toxoplasma gondii alpha tubulin TUBA1 0.1237 0.2358 0.7463
Echinococcus multilocularis integrin alpha ps 0.0076 0.0116 0.0115
Echinococcus granulosus tubulin alpha chain 0.1237 0.2358 0.6308
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0092 0.0379
Echinococcus granulosus L aminoadipate semialdehyde 0.0268 0.0486 0.1298
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Onchocerca volvulus 0.0503 0.094 1
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0053 0.0165
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.012 0.02 0.0847
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0191 0.0337 0.1065
Schistosoma mansoni hypothetical protein 0.1951 0.3738 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0922 0.175 0.5537
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.094 0.2972
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0246 0.0775
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0071 0.0106 0.0282
Loa Loa (eye worm) integrin beta-2 0.0348 0.0641 0.2028
Trichomonas vaginalis tubulin beta chain, putative 0.1237 0.2358 0.7463
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Schistosoma mansoni glutaminase 0.028 0.051 0.1364
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0005 0.0004
Echinococcus granulosus Protein patched homolog 1 0.0353 0.0651 0.1739
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.002 0.007
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.002 0.0203
Echinococcus granulosus Tubulin beta 2C chain 0.1652 0.316 0.8453
Schistosoma mansoni unc-13 (munc13) 0.002 0.0008 0.0021
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.002 0.0008 0.0007
Echinococcus granulosus Niemann Pick C1 protein 0.0823 0.1558 0.4167
Leishmania major cathepsin L-like protease 0.0019 0.0005 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0004 0.0009
Schistosoma mansoni blooms syndrome DNA helicase 0.003 0.0026 0.0069
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.008 0.0124 0.0123
Echinococcus granulosus follistatin 0.0042 0.005 0.0132
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.008 0.0123 0.0122
Echinococcus granulosus ferritin 0.0027 0.002 0.0051
Treponema pallidum cell division protein FtsZ 0.0419 0.0779 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0419 0.0779 0.2463
Brugia malayi MH1 domain containing protein 0.0019 0.0006 0.0016
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.005 0.0065 0.0064
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0032 0.003 0.0083
Brugia malayi Cathepsin L-like precursor 0.0019 0.0005 0.0011
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1237 0.2358 0.7463
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0075 0.0114 0.1423
Schistosoma mansoni integrin alpha-ps 0.0076 0.0116 0.031
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0161 0.0279 0.0743
Leishmania major beta tubulin 0.1652 0.316 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0048 0.0129
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.002 0.0008 0.0021
Mycobacterium tuberculosis Conserved protein 0.0191 0.0337 0.1437
Echinococcus granulosus histone acetyltransferase KAT2B 0.0158 0.0273 0.0728
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0005 0.0011
Echinococcus granulosus tubulin subunit TubB 0.1237 0.2358 0.6308
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0036 0.011
Onchocerca volvulus 0.0032 0.003 0.0273
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0065 0.0203
Brugia malayi chromobox protein homolog 3 0.0041 0.0047 0.0146
Schistosoma mansoni Smad4 0.0035 0.0036 0.0098
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi nuclear receptor NHR-67 0.0071 0.0106 0.0333
Brugia malayi nuclear receptor NHR-88 0.0071 0.0106 0.0333
Echinococcus granulosus epidermal growth factor receptor 0.0262 0.0474 0.1266
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0151 0.0261 0.026
Giardia lamblia Gamma tubulin 0.098 0.1861 0.5886
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0246 0.0658
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.002 0.0008 0.0021
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0817 0.1548 0.4898
Echinococcus granulosus expressed protein 0.0027 0.002 0.0051
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0117 0.0194 0.0193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0191 0.0337 0.0902
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0075 0.02
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Mycobacterium tuberculosis Probable oxidoreductase 0.0133 0.0226 0.0958
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.004
Echinococcus multilocularis integrin alpha ps 0.0076 0.0116 0.0115
Brugia malayi Thioredoxin reductase 0.0053 0.007 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0527 0.1665
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Entamoeba histolytica hypothetical protein 0.008 0.0124 0.0391
Brugia malayi Tubulin beta chain 0.0503 0.094 0.2972
Schistosoma mansoni organic anion transporter 0.0062 0.0088 0.0237
Loa Loa (eye worm) tubulin alpha 2 0.0817 0.1548 0.4898
Mycobacterium tuberculosis Probable esterase LipL 0.0191 0.0337 0.1437
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0005 0.0011
Loa Loa (eye worm) tubulin beta-4 chain 0.1652 0.316 1
Toxoplasma gondii tubulin, putative 0.0057 0.0078 0.0248
Echinococcus granulosus tubulin subunit beta 0.1652 0.316 0.8453
Mycobacterium leprae cell division protein FtsZ 0.0419 0.0779 1
Leishmania major isocitrate dehydrogenase, putative 0.002 0.0008 0.0021
Plasmodium vivax patched family protein, putative 0.005 0.0065 0.0194
Echinococcus granulosus integrin alpha ps 0.0037 0.0039 0.0102
Schistosoma mansoni hypothetical protein 0.0065 0.0094 0.0251
Trypanosoma brucei alpha tubulin 0.1237 0.2358 0.7463
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0419 0.0779 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.007 0.0286
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.012 0.02 0.2498
Mycobacterium tuberculosis Cell division protein FtsZ 0.0419 0.0779 0.3341
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0151 0.0261 0.0822
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0019 0.019
Loa Loa (eye worm) hypothetical protein 0.0268 0.0486 0.1535
Onchocerca volvulus 0.005 0.0065 0.0646
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0039 0.0121
Schistosoma mansoni smad1 5 8 and 0.0035 0.0036 0.0098
Loa Loa (eye worm) hypothetical protein 0.008 0.0123 0.0386
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0007 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0265 0.0481 0.152
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0364 0.1149
Loa Loa (eye worm) hypothetical protein 0.0042 0.005 0.0156
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0151 0.0261 0.0695
Plasmodium falciparum ataxin-2 like protein, putative 0.0265 0.0481 0.1512
Brugia malayi Probable isocitrate dehydrogenase 0.002 0.0008 0.0021
Echinococcus granulosus tumor protein p63 0.0376 0.0694 0.1856
Echinococcus granulosus intermediate filament protein 0.003 0.0027 0.0068
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1652 0.316 0.3159
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Brugia malayi beta-lactamase family protein 0.0191 0.0337 0.1065
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0048 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0026 0.008
Loa Loa (eye worm) hypothetical protein 0.003 0.0027 0.0081
Echinococcus multilocularis tubulin alpha 1C chain 0.1237 0.2358 0.2357
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.008 0.0123 0.0386
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Loa Loa (eye worm) patched family protein 0.005 0.0065 0.0203
Brugia malayi MH2 domain containing protein 0.0035 0.0036 0.0112
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0005 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0114 0.0358
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Plasmodium falciparum thioredoxin reductase 0.0053 0.007 0.021
Loa Loa (eye worm) hypothetical protein 0.0191 0.0337 0.1065
Echinococcus multilocularis epidermal growth factor receptor 0.0483 0.0903 0.0902
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.011 0.0346
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0106 0.1088
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0527 0.1665
Schistosoma mansoni tyrosine kinase 0.0255 0.0461 0.1233
Brugia malayi PAS domain containing protein 0.0054 0.0073 0.0228
Trichomonas vaginalis tubulin, putative 0.0503 0.094 0.2972
Plasmodium falciparum lipid/sterol:H+ symporter 0.005 0.0065 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.0125
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0048 0.0152
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0239 0.0753
Brugia malayi Cell division protein ftsZ 0.0419 0.0779 0.2463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Brugia malayi hypothetical protein 0.0071 0.0106 0.0333
Loa Loa (eye worm) tubulin alpha chain 0.1237 0.2358 0.7463
Toxoplasma gondii isocitrate dehydrogenase 0.0166 0.029 0.0917
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.002 0.021
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0065 0.0203
Onchocerca volvulus Protein patched homolog 0.005 0.0065 0.0646
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0021
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0166 0.029 0.1233
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.007 0.0219
Schistosoma mansoni apoferritin-2 0.0027 0.002 0.0054
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0835 0.1582 0.4234
Leishmania major beta tubulin 0.1652 0.316 1
Leishmania major cathepsin L-like protease 0.0019 0.0005 0.0011
Echinococcus multilocularis hypothetical protein 0.1237 0.2358 0.2357
Echinococcus multilocularis expressed protein 0.0042 0.005 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0335 0.1057
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Brugia malayi Tubulin alpha-2 chain 0.1237 0.2358 0.7463
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0048 0.0149
Echinococcus granulosus chromobox protein 1 0.0072 0.0109 0.0288
Echinococcus granulosus FTZ F1 alpha 0.0151 0.0261 0.0695
Schistosoma mansoni tyrosine kinase 0.0054 0.0073 0.0197
Loa Loa (eye worm) TK protein kinase 0.0047 0.0059 0.0184
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Echinococcus multilocularis Niemann Pick C1 protein 0.1176 0.224 0.2239
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0007 0.0018
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0075 0.0114 0.0361
Echinococcus multilocularis ferritin 0.0027 0.002 0.0019
Echinococcus granulosus beta tubulin 0.1652 0.316 0.8453
Loa Loa (eye worm) hypothetical protein 0.0191 0.0337 0.1065
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Schistosoma mansoni hypothetical protein 0.0306 0.0559 0.1496
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0151 0.0261 0.0822
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0048 0.0149
Echinococcus multilocularis Tubulin beta 2C chain 0.1652 0.316 0.3159
Schistosoma mansoni tyrosine kinase 0.0262 0.0474 0.1269
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Echinococcus multilocularis 0.0148 0.0255 0.0254
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0073 0.0072
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0109 0.0341
Schistosoma mansoni cpg binding protein 0.0125 0.021 0.0562
Loa Loa (eye worm) hypothetical protein 0.0823 0.1558 0.4929
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0094 0.0294
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0062 0.0088 0.0234
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0046 0.0141
Brugia malayi photoreceptor-specific nuclear receptor 0.0151 0.0261 0.0822
Loa Loa (eye worm) hypothetical protein 0.003 0.0027 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0048 0.0149
Schistosoma mansoni tubulin subunit beta 0.1652 0.316 0.8454
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.059 0.1109 0.1108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0151 0.0261 0.0697
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0047 0.0146
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.003 0.0092
Brugia malayi sodium-independent organic anion transporter family protein 0.0062 0.0088 0.0277
Loa Loa (eye worm) hypothetical protein 0.0265 0.0481 0.152
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0066 0.0206
Echinococcus granulosus tubulin alpha chain 0.1237 0.2358 0.6308
Trichomonas vaginalis ferritin, putative 0.0027 0.002 0.006
Schistosoma mansoni hypothetical protein 0.014 0.0239 0.064
Schistosoma mansoni hypothetical protein 0.1951 0.3738 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Echinococcus multilocularis cysteine protease 0.0019 0.0005 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0335 0.1057
Loa Loa (eye worm) hypothetical protein 0.0095 0.0151 0.0476
Echinococcus multilocularis ecdysone induced protein 78C 0.0151 0.0261 0.026
Loa Loa (eye worm) Smad1 0.0035 0.0036 0.0112
Schistosoma mansoni hypothetical protein 0.1285 0.2451 0.6558
Leishmania major cytochrome p450-like protein 0.0026 0.0019 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0045 0.0141
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.0355 0.1119
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0007 0.0018
Echinococcus granulosus cpg binding protein 0.0125 0.021 0.0559
Echinococcus granulosus lamin dm0 0.003 0.0027 0.0068
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0073 0.0194
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0527 0.1665
Loa Loa (eye worm) hypothetical protein 0.0191 0.0337 0.1065
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.002 0.0154
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0043 0.0134
Echinococcus granulosus neuropeptide s receptor 0.0526 0.0985 0.2634
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Onchocerca volvulus 0.005 0.0065 0.0646
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.002 0.0203
Brugia malayi hypothetical protein 0.0251 0.0453 0.1431
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Schistosoma mansoni tyrosine kinase 0.0022 0.0011 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0246 0.0655
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0094 0.0093
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.002 0.021
Loa Loa (eye worm) tubulin alpha 2 0.0315 0.0577 0.1823
Mycobacterium tuberculosis Probable hydrolase 0.0191 0.0337 0.1437
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0004 0.0009
Echinococcus multilocularis beta tubulin 0.1652 0.316 0.3159
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0092
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0078 0.0205
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0922 0.175 0.5539
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Echinococcus granulosus alpha tubulin 0.1237 0.2358 0.6308
Brugia malayi nuclear hormone receptor family member odr-7 0.0071 0.0106 0.0333
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0004 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0246 0.0658
Leishmania major beta tubulin 0.1652 0.316 1
Brugia malayi hypothetical protein 0.0062 0.0088 0.0277
Mycobacterium ulcerans beta-lactamase 0.0191 0.0337 0.4302
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0092 0.0243
Onchocerca volvulus 0.0062 0.0088 0.0896
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0004 0.0009
Brugia malayi hypothetical protein 0.005 0.0065 0.0203
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0073 0.0194
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0133 0.0226 0.0958
Echinococcus multilocularis tumor protein p63 0.0376 0.0694 0.0694
Leishmania major epsilon tubulin, putative 0.0979 0.186 0.5885
Echinococcus multilocularis protein patched 0.0353 0.0651 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0045 0.0141
Echinococcus multilocularis chromobox protein 1 0.0072 0.0109 0.0108
Trypanosoma brucei beta tubulin 0.0922 0.175 0.5537
Echinococcus multilocularis c src tyrosine kinase 0.0022 0.0011 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0019 0.0056
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0075 0.0114 0.1423
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0106 0.0105
Trypanosoma brucei alpha tubulin 0.1237 0.2358 0.7463
Echinococcus multilocularis tubulin delta chain 0.0419 0.0779 0.0778
Loa Loa (eye worm) hypothetical protein 0.0181 0.0319 0.1007
Loa Loa (eye worm) nuclear factor I 0.0019 0.0006 0.0016
Brugia malayi mbt repeat family protein 0.005 0.0065 0.0201
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Trypanosoma cruzi tubulin delta chain 0.0775 0.1467 0.464
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0065 0.017
Schistosoma mansoni hypothetical protein 0.0119 0.0199 0.0531
Brugia malayi alpha-tubulin 0.1237 0.2358 0.7463
Echinococcus granulosus integrin alpha 3 0.013 0.022 0.0587
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0004 0.0012
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0817 0.1548 0.4898
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.008 0.0124 0.0328
Trypanosoma brucei zeta tubulin, putative 0.1014 0.1929 0.6102
Brugia malayi AMP-binding enzyme family protein 0.0026 0.002 0.0059
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.002 0.0062
Mycobacterium ulcerans hypothetical protein 0.0026 0.002 0.0203
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.002 0.0008 0.0021
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0166 0.029 0.0914
Echinococcus multilocularis tubulin beta 1 chain 0.1652 0.316 0.3159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0151 0.0261 0.0822
Trichomonas vaginalis conserved hypothetical protein 0.0353 0.0651 0.2057
Echinococcus granulosus tubulin alpha 1C chain 0.1237 0.2358 0.6308
Echinococcus multilocularis integrin alpha ps 0.0037 0.0039 0.0038
Echinococcus granulosus tubulin alpha 0.0922 0.175 0.4681
Trichomonas vaginalis tubulin beta chain, putative 0.1237 0.2358 0.7463
Schistosoma mansoni survival motor neuron protein 0.0054 0.0072 0.0193
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0066 0.0206
Trichomonas vaginalis glutaminase, putative 0.028 0.051 0.161
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0036 0.0095
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0007 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Echinococcus granulosus tyrosine protein kinase HCK 0.0039 0.0045 0.0117
Loa Loa (eye worm) hypothetical protein 0.008 0.0123 0.0386
Trypanosoma cruzi beta tubulin, putative 0.1652 0.316 1
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0027 0.0021 0.0064
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0065 0.0173
Brugia malayi hypothetical protein 0.005 0.0065 0.0203
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0277
Loa Loa (eye worm) hypothetical protein 0.0042 0.005 0.0156
Loa Loa (eye worm) hypothetical protein 0.1237 0.2358 0.7463
Echinococcus granulosus neuroglian 0.0027 0.002 0.0051
Echinococcus granulosus sterol regulatory element binding protein 0.0353 0.0651 0.1739
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0034 0.0034 0.0103
Brugia malayi bHLH-PAS transcription factor 0.004 0.0046 0.0142
Echinococcus multilocularis L aminoadipate semialdehyde 0.0268 0.0486 0.0485
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0092 0.0288
Schistosoma mansoni tubulin subunit alpha 0.1237 0.2358 0.6309
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Trichomonas vaginalis helicase, putative 0.0027 0.002 0.0061
Echinococcus granulosus Tubulin alpha 1 chain 0.1237 0.2358 0.6308
Schistosoma mansoni thyroid hormone receptor 0.0291 0.0531 0.1421
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.002 0.0068
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0051 0.005
Echinococcus granulosus integrin beta 2 0.0258 0.0467 0.1247
Echinococcus granulosus dnaJ subfamily B 0.1285 0.2451 0.6557
Echinococcus granulosus survival motor neuron protein 1 0.0263 0.0477 0.1273
Schistosoma mansoni tubulin subunit beta 0.1652 0.316 0.8454
Loa Loa (eye worm) hypothetical protein 0.0041 0.0047 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.0125
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0201
Loa Loa (eye worm) hypothetical protein 0.003 0.0027 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0065 0.0203
Brugia malayi nuclear hormone receptor 0.0071 0.0106 0.0333
Trypanosoma cruzi tubulin gamma chain 0.098 0.1861 0.589
Echinococcus multilocularis tubulin alpha chain 0.1237 0.2358 0.2357
Plasmodium falciparum tubulin epsilon chain, putative 0.0979 0.186 0.5881
Brugia malayi AMP-binding enzyme family protein 0.0026 0.002 0.0059
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0019 0.0005 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0092 0.0246
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.0057 0.0177
Trichomonas vaginalis tubulin gamma chain, putative 0.098 0.1861 0.589
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0009 0.0024
Echinococcus granulosus bloom syndrome protein 0.0046 0.0057 0.015
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0019 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Onchocerca volvulus Protein patched homolog 0.005 0.0065 0.0646
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0094 0.0294
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0018
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0007 0.0018
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0004 0.0009
Schistosoma mansoni hypothetical protein 0.034 0.0626 0.1675
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0151 0.0261 0.026
Leishmania major cathepsin L-like protease 0.0019 0.0005 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0151 0.0261 0.0695
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0032 0.003 0.0029
Leishmania major zeta tubulin, putative 0.1014 0.1929 0.6102
Echinococcus granulosus twitchin 0.0027 0.0021 0.0053
Onchocerca volvulus Putative organic anion transporter 0.0062 0.0088 0.0896
Onchocerca volvulus 0.004 0.0046 0.0442
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.0125
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0166 0.029 0.0906
Treponema pallidum ATP-dependent RNA helicase 0.0027 0.0021 0.0272
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0065 0.0201
Echinococcus granulosus Immunoglobulin 0.0023 0.0014 0.0034
Brugia malayi hypothetical protein 0.0457 0.0851 0.269
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0007 0.0021
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0048 0.0126
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0027 0.0021 0.0177
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0071 0.0106 0.0333
Loa Loa (eye worm) hypothetical protein 0.0817 0.1548 0.4898
Brugia malayi Myosin head containing protein 0.005 0.0065 0.0203
Schistosoma mansoni tubulin subunit epsilon 0.0979 0.186 0.4976
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0059
Echinococcus multilocularis beta LACTamase domain containing family member 0.0191 0.0337 0.0336
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0151 0.0261 0.0822
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0117 0.0194 0.0516
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0166 0.029 0.0776
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.014
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0053 0.0518
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0151 0.0261 0.0697
Echinococcus multilocularis muscleblind protein 0.0148 0.0254 0.0253
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.008 0.0123 0.0386
Brugia malayi ecdysone receptor 0.0071 0.0106 0.0333
Onchocerca volvulus 0.005 0.0065 0.0646
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0191 0.0337 0.1437
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.014 0.0239 0.0238
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0092 0.1136
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0476 0.0889 0.2812
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0073 0.0072
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0162 0.0282 0.0754
Schistosoma mansoni DNA helicase recq1 0.0032 0.003 0.0081
Entamoeba histolytica tubulin alpha-1 chain 0.1237 0.2358 0.7463
Toxoplasma gondii alpha-tubulin I, putative 0.1237 0.2358 0.7463
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0206
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0025 0.0068
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.005 0.0065 0.0203
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0151 0.0261 0.0695
Giardia lamblia Beta tubulin 0.1652 0.316 1
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.014 0.0239 0.0637
Brugia malayi MH1 domain containing protein 0.0035 0.0036 0.0112
Onchocerca volvulus Bile acid receptor homolog 0.0151 0.0261 0.2737
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0004 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0019 0.0058
Toxoplasma gondii hypothetical protein 0.005 0.0065 0.0206
Trichomonas vaginalis D-aminoacylase, putative 0.0191 0.0337 0.1065
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0018
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0019 0.0056
Echinococcus granulosus agrin 0.0042 0.005 0.0132
Brugia malayi hypothetical protein 0.008 0.0123 0.0386
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0094 0.0248
Echinococcus granulosus tubulin gamma 1 chain 0.098 0.1861 0.4979
Schistosoma mansoni tyrosine kinase 0.0054 0.0073 0.0197
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0191 0.0337 0.1437
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.094 0.2972
Brugia malayi Patched protein homolog 1 0.005 0.0065 0.0203
Schistosoma mansoni retinoic acid receptor RXR 0.0261 0.0472 0.1264
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0053 0.0156
Brugia malayi Cathepsin L-like precursor 0.0019 0.0005 0.0011
Schistosoma mansoni tyrosine kinase 0.0117 0.0194 0.0519
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Trichomonas vaginalis tubulin gamma chain, putative 0.0419 0.0779 0.2463
Echinococcus multilocularis tubulin alpha 1C chain 0.1237 0.2358 0.2357
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.002 0.0008 0.0049
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.002 0.0203
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0007 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0151 0.0261 0.0697
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0024 0.0073
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0191 0.0337 0.1065
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0106 0.0285
Leishmania major hypothetical protein, conserved 0.0191 0.0337 0.1065
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0151 0.0261 0.026
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0005 0.001
Echinococcus multilocularis geminin 0.1951 0.3738 0.3737
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0016 0.0046
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0039 0.0102
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0007 0.0018
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0071 0.0106 0.0285
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0065 0.0063
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0078
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0019 0.0005 0.0004
Echinococcus multilocularis Smad4 0.0035 0.0036 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0051 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0151 0.0261 0.0822
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0027 0.0021 0.0064
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.005 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0065 0.0063
Echinococcus granulosus Tubulin beta 2C chain 0.1652 0.316 0.8453
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0106 0.1088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0166 0.029 0.0289
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0005 0.0015
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.002 0.0008 0.0007
Echinococcus multilocularis chromobox protein 1 0.0072 0.0109 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Brugia malayi beta-lactamase family protein 0.0191 0.0337 0.1065
Schistosoma mansoni coup transcription factor 0.0151 0.0261 0.0697
Trichomonas vaginalis tubulin beta chain, putative 0.1237 0.2358 0.7463
Trypanosoma brucei tubulin gamma chain 0.098 0.1861 0.589
Brugia malayi hypothetical protein 0.0171 0.0299 0.0945
Leishmania major trypanothione reductase 0.0053 0.007 0.0219
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0027 0.0081
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0151 0.0261 0.0695
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0036 0.0098
Toxoplasma gondii patched family protein 0.005 0.0065 0.0206
Brugia malayi MH2 domain containing protein 0.0035 0.0036 0.0112
Onchocerca volvulus 0.0191 0.0337 0.3557
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0019 0.0058
Schistosoma mansoni tubulin subunit beta 0.1652 0.316 0.8454
Trichomonas vaginalis tubulin beta chain, putative 0.1237 0.2358 0.7463
Loa Loa (eye worm) TK/EGFR protein kinase 0.0483 0.0903 0.2854
Leishmania major cathepsin L-like protease 0.0071 0.0106 0.0331
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0026 0.0078
Echinococcus granulosus muscleblind protein 0.0148 0.0254 0.0677
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Trypanosoma brucei tubulin delta chain 0.0775 0.1467 0.464
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.011 0.0346
Loa Loa (eye worm) tubulin alpha chain 0.1237 0.2358 0.7463
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0246 0.0655
Loa Loa (eye worm) hypothetical protein 0.0251 0.0453 0.1431
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0004 0.0009
Schistosoma mansoni integrin alpha 0.017 0.0297 0.0795
Trichomonas vaginalis tubulin gamma chain, putative 0.0979 0.186 0.5885
Leishmania major beta tubulin 0.1652 0.316 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.007 0.0069
Brugia malayi SRC-1 0.0054 0.0073 0.0229
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.004
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0277
Plasmodium vivax vivapain-2 0.0019 0.0005 0.0002
Schistosoma mansoni single-minded 0.0054 0.0073 0.0196
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0008
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.005 0.016
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0025 0.0065
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.002 0.0008 0.0018
Loa Loa (eye worm) integrin alpha pat-2 0.0262 0.0475 0.1501
Loa Loa (eye worm) ctsf protein 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0059
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0084 0.0261
Mycobacterium ulcerans putative regulatory protein 0.004 0.0046 0.0544
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0007 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0021 0.0063
Schistosoma mansoni steroid hormone receptor ad4bp 0.0151 0.0261 0.0697
Schistosoma mansoni cpg binding protein 0.0118 0.0197 0.0527
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0059
Echinococcus granulosus nuclear receptor nhr 48 0.0071 0.0106 0.0282
Plasmodium vivax delta tubulin, putative 0.0419 0.0779 0.2456
Leishmania major delta tubulin, putative 0.0775 0.1467 0.464
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0007 0.0009
Brugia malayi Kelch motif family protein 0.0053 0.0071 0.0221
Toxoplasma gondii ABC1 family protein 0.0191 0.0337 0.1067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0246 0.0245
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0289 0.0527 0.1665
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0048 0.0149
Echinococcus granulosus tubulin beta 4A class IVa 0.1652 0.316 0.8453
Loa Loa (eye worm) hypothetical protein 0.008 0.0123 0.0386
Brugia malayi Cathepsin L-like precursor 0.0019 0.0005 0.0011
Plasmodium falciparum tubulin beta chain 0.1652 0.316 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0075 0.0114 1
Trichomonas vaginalis tubulin alpha chain, putative 0.1652 0.316 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0364 0.1149
Brugia malayi Smad1 0.0035 0.0036 0.0112
Leishmania major eukaryotic initiation factor 4a, putative 0.0027 0.0021 0.0064
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0123 0.0386
Mycobacterium ulcerans cell division protein FtsZ 0.0419 0.0779 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0053 0.0168
Brugia malayi Muscleblind-like protein 0.0148 0.0254 0.0801
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0106 0.0331
Loa Loa (eye worm) hypothetical protein 0.0129 0.0217 0.0684
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.005 0.0065 0.0203
Brugia malayi Cathepsin L-like precursor 0.0019 0.0005 0.0011
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0075 0.0114 0.0349
Echinococcus multilocularis sterol regulatory element binding protein 0.0353 0.0651 0.065
Loa Loa (eye worm) transcription factor SMAD2 0.0515 0.0964 0.305
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0053 0.0071 0.0221
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0061
Echinococcus multilocularis bloom syndrome protein 0.0046 0.0057 0.0056
Giardia lamblia GTOR 0.005 0.0065 0.0194
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0036 0.011
Schistosoma mansoni agrin 0.0042 0.005 0.0135
Entamoeba histolytica tubulin alpha chain, putative 0.1237 0.2358 0.7463
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0166 0.029 0.0914
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0027 0.0021 0.0055
Onchocerca volvulus 0.005 0.0065 0.0646
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0062 0.0088 0.0277
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.02 0.0631
Plasmodium falciparum glutathione reductase 0.0053 0.007 0.021
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0043 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0021 0.0062
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0027 0.0021 0.0067
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0027 0.0021 0.002
Echinococcus granulosus tubulin delta chain 0.0419 0.0779 0.2082
Schistosoma mansoni vesicular amine transporter 0.0023 0.0014 0.0036
Loa Loa (eye worm) DR-78 0.0071 0.0106 0.0333
Loa Loa (eye worm) hypothetical protein 0.0042 0.005 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Brugia malayi sodium-independent organic anion transporter family protein 0.0062 0.0088 0.0277
Toxoplasma gondii transporter, major facilitator family protein 0.0062 0.0088 0.028
Echinococcus multilocularis neuropeptide receptor A26 0.0526 0.0985 0.0984
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.002 0.0059
Mycobacterium tuberculosis Conserved protein 0.0191 0.0337 0.1437
Onchocerca volvulus 0.003 0.0027 0.0235
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0023 0.0014 0.0036
Brugia malayi hypothetical protein 0.008 0.0124 0.0388
Echinococcus multilocularis neuropeptide s receptor 0.0526 0.0985 0.0984
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.002 0.0008 0.0021
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.012 0.02 0.0847
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0072 0.0226
Brugia malayi protein C24B5.3 0.005 0.0065 0.0203
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0073 0.0072
Trichomonas vaginalis tubulin, putative 0.1652 0.316 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0026 0.0078
Echinococcus granulosus expressed conserved protein 0.0773 0.1462 0.3909
Echinococcus granulosus defective proboscis extension response 0.0023 0.0014 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0033 0.0103
Echinococcus multilocularis tyrosine protein kinase HCK 0.0039 0.0045 0.0044
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0019 0.0056
Loa Loa (eye worm) patched family protein 0.005 0.0065 0.0203
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.0354 0.0945
Echinococcus granulosus insulin receptor 0.0157 0.0273 0.0727
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0527 0.1665
Loa Loa (eye worm) hypothetical protein 0.0065 0.0094 0.0294
Loa Loa (eye worm) hypothetical protein 0.0053 0.0071 0.0221
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.094 0.2972
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0007 0.0009
Loa Loa (eye worm) patched family protein 0.005 0.0065 0.0203
Onchocerca volvulus 0.005 0.0065 0.0646
Loa Loa (eye worm) SRC-1 0.0054 0.0073 0.0229
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0043 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Brugia malayi Steroid receptor seven-up type 2 0.0151 0.0261 0.0822
Echinococcus multilocularis tubulin alpha 0.0922 0.175 0.1749
Echinococcus multilocularis tubulin gamma 1 chain 0.098 0.1861 0.1861
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0191 0.0337 0.4302
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi hypothetical protein 0.0053 0.0071 0.0221
Onchocerca volvulus 0.0062 0.0088 0.0896
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0026 0.008
Plasmodium falciparum ataxin-2 like protein, putative 0.0265 0.0481 0.1512
Brugia malayi MH2 domain containing protein 0.0515 0.0964 0.305
Onchocerca volvulus 0.0026 0.002 0.016
Schistosoma mansoni tyrosine kinase 0.0262 0.0474 0.1269
Schistosoma mansoni thyroid hormone receptor 0.0291 0.0531 0.1421
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0094 0.0248
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0119 0.0199 0.0197
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0016
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.002 0.0203
Leishmania major cathepsin L-like protease 0.0071 0.0106 0.0331
Leishmania major eukaryotic initiation factor 4a, putative 0.0027 0.0021 0.0064
Schistosoma mansoni tyrosine kinase 0.0157 0.0273 0.0729
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0021 0.0064
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0061 0.018
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0335 0.1057
Giardia lamblia Alpha-tubulin 0.1237 0.2358 0.746
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0042 0.005 0.0156
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0059 0.0058
Brugia malayi Tubulin alpha chain 0.1237 0.2358 0.7463
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0022 0.0011 0.0029
Brugia malayi nuclear receptor RXR 0.008 0.0123 0.0386
Echinococcus multilocularis integrin alpha 3 0.013 0.022 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0151 0.0261 0.0822
Loa Loa (eye worm) hypothetical protein 0.0041 0.0048 0.0149
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0073 0.0072
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.0057 0.0177
Echinococcus granulosus Tubulin beta 2C chain 0.1652 0.316 0.8453
Echinococcus multilocularis Immunoglobulin 0.0023 0.0014 0.0013
Toxoplasma gondii thioredoxin reductase 0.0053 0.007 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0419 0.0779 0.2463
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0047 0.0059 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0005 0.0011
Brugia malayi MAP kinase sur-1 0.005 0.0066 0.0206
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0027 0.002 0.021
Echinococcus granulosus lamin 0.003 0.0027 0.0068
Brugia malayi Patched related family protein 12 0.005 0.0065 0.0203
Echinococcus granulosus Tubulin beta 2C chain 0.1652 0.316 0.8453
Loa Loa (eye worm) hypothetical protein 0.0734 0.1387 0.4388
Schistosoma mansoni hypothetical protein 0.0054 0.0072 0.0193
Echinococcus multilocularis Tubulin beta 2C chain 0.1652 0.316 0.3159
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi Cytochrome P450 family protein 0.0026 0.0019 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0335 0.1057
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0046 0.0141
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0527 0.1665
Entamoeba histolytica tubulin gamma chain 0.098 0.1861 0.5891
Echinococcus multilocularis insulin receptor 0.0157 0.0273 0.0272
Loa Loa (eye worm) glutaminase 2 0.028 0.051 0.161
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0001 0.0003
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0022 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0092
Echinococcus multilocularis tubulin alpha 3 chain 0.1237 0.2358 0.2357
Trypanosoma brucei beta tubulin 0.1652 0.316 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0151 0.0261 0.2737
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.002 0.0203
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.011 0.0346
Toxoplasma gondii cathepsin CPL 0.0019 0.0005 0.0015
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0066 0.0206
Schistosoma mansoni follistatin 0.0042 0.005 0.0135
Loa Loa (eye worm) RecQ helicase 0.0046 0.0057 0.0177
Brugia malayi hypothetical protein 0.0181 0.0319 0.1007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0064
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi tubulin alpha-2 chain 0.1237 0.2358 0.7463
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0048 0.0149
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0007 0.0018
Trichomonas vaginalis tubulin epsilon chain, putative 0.1237 0.2358 0.7463
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.005 0.0065 0.0172
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.0151 0.0261 0.0822
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0046 0.0141
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.005 0.016
Echinococcus multilocularis tyrosine protein kinase Blk 0.0047 0.0059 0.0058
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0004 0.0009
Schistosoma mansoni ferritin 0.0027 0.002 0.0054
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0277
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0092 0.1136
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.003 0.0092
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0106 0.0331
Schistosoma mansoni RAR-like nuclear receptor 0.0151 0.0261 0.0697
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Leishmania major beta tubulin 0.1652 0.316 1
Echinococcus multilocularis follistatin 0.0042 0.005 0.0049
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0071 0.0106 0.0105
Entamoeba histolytica hypothetical protein 0.0075 0.0114 0.0361
Schistosoma mansoni hypothetical protein 0.0166 0.029 0.0775
Schistosoma mansoni zinc finger protein 0.0071 0.0106 0.0285
Brugia malayi hypothetical protein 0.0062 0.0088 0.0277
Schistosoma mansoni lamin 0.003 0.0027 0.0071
Brugia malayi SPARC precursor 0.0042 0.005 0.0156
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0114 0.138
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0092 0.0091
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0073 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0206
Plasmodium falciparum alpha tubulin 2 0.1237 0.2358 0.746
Giardia lamblia Delta tubulin 0.0419 0.0779 0.2456
Echinococcus multilocularis dnaJ subfamily B 0.1285 0.2451 0.245
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.007 0.021
Loa Loa (eye worm) patched family protein 0.005 0.0065 0.0203
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.005 0.0065 0.0203
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.002 0.0203
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0246 0.0658
Echinococcus granulosus geminin 0.1951 0.3738 1
Brugia malayi hypothetical protein 0.0265 0.0481 0.152
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Schistosoma mansoni organic anion transporter 0.0062 0.0088 0.0237
Brugia malayi steroid hormone receptor 0.0151 0.0261 0.0822
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Loa Loa (eye worm) hypothetical protein 0.0191 0.0337 0.1065
Schistosoma mansoni transcription factor LCR-F1 0.008 0.0124 0.0331
Trichomonas vaginalis esterase, putative 0.0191 0.0337 0.1065
Onchocerca volvulus 0.005 0.0065 0.064
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0151 0.0261 0.026
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0042 0.005 0.016
Plasmodium falciparum tubulin gamma chain 0.098 0.1861 0.5886
Echinococcus granulosus Smad4 0.0035 0.0036 0.0095
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0094 0.0294
Schistosoma mansoni alpha tubulin 0.1237 0.2358 0.6309
Plasmodium falciparum tubulin delta chain, putative 0.0419 0.0779 0.2456
Plasmodium vivax hypothetical protein, conserved 0.0191 0.0337 0.1057
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0027 0.0021 0.0054
Schistosoma mansoni tubulin subunit delta 0.0419 0.0779 0.2084
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0734 0.1387 0.4388
Mycobacterium tuberculosis Probable lipase LipE 0.0191 0.0337 0.1437
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.001
Brugia malayi CXXC zinc finger family protein 0.0118 0.0197 0.062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0007 0.0259
Plasmodium vivax tubulin alpha chain, putative 0.1237 0.2358 0.746
Trichomonas vaginalis tubulin beta chain, putative 0.0503 0.094 0.2972
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0075 0.0114 0.0475
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0078 0.0077
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0056 0.0078 0.0243
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0166 0.029 0.0906
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0151 0.0261 0.0822
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.002 0.0064
Toxoplasma gondii beta-1 tubulin, putative 0.1652 0.316 1
Brugia malayi prostaglandin transporter 0.0062 0.0088 0.0277
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.002 0.0059
Schistosoma mansoni alpha tubulin 0.1237 0.2358 0.6309
Trypanosoma cruzi PAB1-binding protein , putative 0.0265 0.0481 0.152
Schistosoma mansoni tyrosine kinase 0.0483 0.0903 0.2415
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0003
Plasmodium falciparum eukaryotic initiation factor 4A 0.0027 0.0021 0.0055
Loa Loa (eye worm) hypothetical protein 0.0353 0.0651 0.2057
Loa Loa (eye worm) tubulin gamma chain 0.098 0.1861 0.589
Schistosoma mansoni hypothetical protein 0.0065 0.0094 0.0251
Loa Loa (eye worm) fibroinase 0.0019 0.0005 0.0011
Echinococcus multilocularis Tubulin alpha 1 chain 0.1237 0.2358 0.2357
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.003 0.0095
Loa Loa (eye worm) alpha-tubulin 0.1237 0.2358 0.7463
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0075 0.0114 0.1423
Brugia malayi AMP-binding enzyme family protein 0.0026 0.002 0.0059
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0043 0.0051 0.0151
Loa Loa (eye worm) hypoxia-induced factor 1 0.0167 0.0292 0.0921
Trypanosoma brucei beta tubulin 0.1652 0.316 1
Brugia malayi MH1 domain containing protein 0.0019 0.0006 0.0016
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0036 0.0095
Brugia malayi Cathepsin L-like precursor 0.0019 0.0005 0.0011
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0062 0.0088 0.0087
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0032 0.003 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0166 0.029 0.0914
Mycobacterium ulcerans hypothetical protein 0.0191 0.0337 0.4302
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.005 0.0065 0.0206
Echinococcus multilocularis Niemann Pick C1 protein 0.0823 0.1558 0.1557
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0073 0.0072
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Echinococcus granulosus c src tyrosine kinase 0.0022 0.0011 0.0026
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0005 0.0002
Entamoeba histolytica tartrate dehydrogenase, putative 0.002 0.0008 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0151 0.0261 0.0822
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0032 0.003 0.0078
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0823 0.1558 0.4931
Onchocerca volvulus Putative organic anion transporter 0.0062 0.0088 0.0896
Echinococcus granulosus Tubulin beta 2C chain 0.1652 0.316 0.8453
Brugia malayi Tubulin alpha chain 0.0419 0.0779 0.2463
Trypanosoma cruzi tubulin delta chain 0.0775 0.1467 0.464
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.012 0.02 0.0847
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0066 0.0206
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Echinococcus granulosus chromobox protein 1 0.0072 0.0109 0.0288
Loa Loa (eye worm) MBCTL1 0.0056 0.0078 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0048 0.0149
Leishmania major beta tubulin 0.1652 0.316 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0007 0.0086
Brugia malayi Cathepsin L-like precursor 0.0019 0.0005 0.0011
Echinococcus multilocularis beta tubulin 0.1652 0.316 0.3159
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0027 0.0021 0.0075
Echinococcus multilocularis tubulin alpha chain 0.1237 0.2358 0.2357
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.0263 0.0477 0.1506
Plasmodium falciparum alpha tubulin 1 0.1237 0.2358 0.746
Echinococcus multilocularis roundabout 2 0.0033 0.0033 0.0032
Schistosoma mansoni DNA helicase recq5 0.0032 0.003 0.0081
Schistosoma mansoni hypothetical protein 0.0037 0.0039 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0065 0.0203
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0335 0.1057
Schistosoma mansoni smad 0.0035 0.0036 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Mycobacterium tuberculosis Conserved protein 0.0191 0.0337 0.1437
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0066 0.0206
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0106 0.0333
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0005 0.0011
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0076 0.0238
Echinococcus granulosus roundabout 2 0.0033 0.0033 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0045 0.0141
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0166 0.029 0.0914
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0027 0.0081
Mycobacterium ulcerans esterase/lipase LipP 0.0191 0.0337 0.4302
Schistosoma mansoni retinoid-x-receptor (RXR) 0.008 0.0123 0.0329
Echinococcus granulosus tubulin alpha 1C chain 0.1237 0.2358 0.6308
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0027 0.0021 0.0064
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0048 0.0129
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Loa Loa (eye worm) tubulin beta chain 0.1652 0.316 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Brugia malayi protein C24B5.3 0.005 0.0065 0.0203
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0061 0.0189
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0246 0.0775
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0045 0.0141
Trypanosoma brucei epsilon tubulin 0.0922 0.175 0.5537
Trypanosoma brucei alpha tubulin 0.1237 0.2358 0.7463
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0027 0.002 0.0051
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0027 0.0021 0.0057
Echinococcus multilocularis expressed conserved protein 0.0773 0.1462 0.1461
Mycobacterium tuberculosis Probable lipase LipD 0.0191 0.0337 0.1437
Schistosoma mansoni hypothetical protein 0.0065 0.0094 0.0251
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0151 0.0261 0.0695
Schistosoma mansoni hypothetical protein 0.034 0.0626 0.1675
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0151 0.0261 0.0697
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Trypanosoma brucei alpha tubulin 0.1237 0.2358 0.7463
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0106 0.0105
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0042 0.005 0.0156
Brugia malayi nuclear hormone receptor family member nhr-6 0.0071 0.0106 0.0333
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Leishmania major hypothetical protein, conserved 0.0265 0.0481 0.152
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0053 0.0165
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0151 0.0261 0.026
Loa Loa (eye worm) TK/ABL protein kinase 0.0244 0.044 0.1389
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0133 0.0226 0.2834
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0065 0.0173
Loa Loa (eye worm) hypothetical protein 0.0457 0.0851 0.269
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0075 0.0114 0.1465
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0021 0.0063
Echinococcus multilocularis integrin beta 2 0.0258 0.0467 0.0466
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0061 0.016
Leishmania major beta tubulin 0.1652 0.316 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.0254 0.0801
Echinococcus multilocularis tubulin subunit beta 0.1652 0.316 0.3159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.0125
Entamoeba histolytica hypothetical protein 0.008 0.0124 0.0391
Trypanosoma brucei alpha tubulin, putative 0.0503 0.094 0.2972
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0065 0.017
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0066 0.0209
Echinococcus granulosus tyrosine protein kinase Blk 0.0047 0.0059 0.0156
Loa Loa (eye worm) hypothetical protein 0.0094 0.015 0.0471
Leishmania major beta tubulin 0.1652 0.316 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.002 0.0154
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0129 0.0217 0.0684
Toxoplasma gondii patched family protein 0.005 0.0065 0.0206
Loa Loa (eye worm) CHromoDomain protein family member 0.0019 0.0005 0.0011
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0053 0.0156
Schistosoma mansoni tyrosine kinase 0.0157 0.0273 0.0729
Brugia malayi hypothetical protein 0.0071 0.0106 0.0333
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0251 0.0453 0.1211
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0065 0.064
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0151 0.0261 0.0822
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0022 0.0011 0.001
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0032 0.003 0.0092
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0007 0.0036
Trichomonas vaginalis tubulin epsilon chain, putative 0.1652 0.316 1
Brugia malayi hypothetical protein 0.005 0.0065 0.0203
Brugia malayi sodium-independent organic anion transporter family protein 0.0062 0.0088 0.0277
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0162 0.0282 0.0281
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.0337 0.1065
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0503 0.094 0.2972
Loa Loa (eye worm) tubulin alpha-2 chain 0.1237 0.2358 0.7463
Schistosoma mansoni tubulin subunit alpha 0.1237 0.2358 0.6309
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0039 0.0038
Echinococcus granulosus tubulin epsilon chain 0.0979 0.186 0.4974
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0027 0.0021 0.002
Loa Loa (eye worm) steroid hormone receptor 0.0151 0.0261 0.0822
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0151 0.0261 0.0697
Schistosoma mansoni hypothetical protein 0.008 0.0124 0.0331
Mycobacterium ulcerans glutaminase 0.028 0.051 0.6527
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0043 0.0134
Brugia malayi intermediate filament protein 0.003 0.0027 0.0081
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0061
Schistosoma mansoni lamin 0.003 0.0027 0.0071
Schistosoma mansoni tubulin subunit gamma 0.098 0.1861 0.498
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0119 0.0199 0.0528
Brugia malayi Patched related family protein 4 0.005 0.0065 0.0203
Plasmodium vivax RNA helicase-1, putative 0.0027 0.0021 0.0055
Schistosoma mansoni tubulin subunit beta 0.1652 0.316 0.8454
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0364 0.1149
Schistosoma mansoni tyrosine kinase 0.0255 0.0461 0.1233
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.0527 0.1665
Echinococcus multilocularis lamin dm0 0.003 0.0027 0.0026
Mycobacterium leprae Probable lipase LipE 0.0191 0.0337 0.4274
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.004
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0106 0.0285
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0151 0.0261 0.0822
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.005 0.0065 0.0174
Brugia malayi Niemann-Pick C1 protein precursor 0.0823 0.1558 0.4929
Leishmania major alpha tubulin 0.1237 0.2358 0.7463
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.002 0.007
Echinococcus multilocularis agrin 0.0042 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0018
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0181 0.0318 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0047 0.0146
Echinococcus multilocularis FTZ F1 alpha 0.0151 0.0261 0.026
Loa Loa (eye worm) hypothetical protein 0.0191 0.0337 0.1065
Loa Loa (eye worm) acetyltransferase 0.0162 0.0282 0.0889
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.0355 0.1119
Schistosoma mansoni smad1 5 8 and 0.0035 0.0036 0.0098
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.011 0.0296
Schistosoma mansoni tyrosine kinase 0.0255 0.0461 0.1233
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0027 0.0021 0.0057
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0003
Leishmania major beta tubulin 0.1652 0.316 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0073 0.0072
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.011 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0005 0.0011
Toxoplasma gondii exonuclease III APE 0.002 0.0007 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0034 0.0103
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0073 0.0196
Loa Loa (eye worm) tubulin beta-1 chain 0.1652 0.316 1
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0007 0.0009
Trypanosoma brucei hypothetical protein, conserved 0.0191 0.0337 0.1065
Echinococcus granulosus tubulin beta 1 chain 0.1652 0.316 0.8453
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0078 0.0077
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0073 0.0194
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0027 0.0021 0.0067
Onchocerca volvulus 0.0118 0.0197 0.2056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0071 0.0106 0.0285
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0151 0.0261 0.026
Onchocerca volvulus 0.0055 0.0075 0.0751
Mycobacterium ulcerans lipase LipD 0.0191 0.0337 0.4302
Giardia lamblia Sgs1 DNA helicase, putative 0.0032 0.003 0.0083
Onchocerca volvulus 0.0062 0.0088 0.0896
Trichomonas vaginalis D-aminoacylase, putative 0.0191 0.0337 0.1065
Onchocerca volvulus 0.0071 0.0106 0.1088
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.0133 0.0227 0.0714
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.007 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0005 0.0015
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0005 0.0004
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.0046 0.0045
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.002 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0024 0.0073
Onchocerca volvulus 0.0062 0.0088 0.0896
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.004 0.0125
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0059
Leishmania major beta tubulin 0.1652 0.316 1
Leishmania major cathepsin L-like protease 0.0071 0.0106 0.0331
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0066 0.0065
Schistosoma mansoni ferritin 0.0027 0.002 0.0054
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.0046 0.012
Mycobacterium leprae conserved hypothetical protein 0.0191 0.0337 0.4274
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0036 0.0112
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0205 0.0364 0.1149
Loa Loa (eye worm) beta-tubulin 0.1652 0.316 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0065 0.0203
Echinococcus multilocularis smad 0.0035 0.0036 0.0035
Schistosoma mansoni smad1 5 8 and 0.0035 0.0036 0.0098
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0333
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0027 0.0021 0.0064
Brugia malayi glutathione reductase 0.0053 0.007 0.0219
Brugia malayi Patched family protein 0.005 0.0065 0.0203
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0166 0.029 0.0914
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0106 0.0282
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0166 0.029 0.0289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0106 0.0331
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0059
Brugia malayi orphan nuclear receptor NR2E1 0.0071 0.0106 0.0333
Schistosoma mansoni tubulin subunit alpha 0.1237 0.2358 0.6309
Entamoeba histolytica cysteine protease, putative 0.0019 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0027 0.0082
Echinococcus granulosus tubulin alpha 3 chain 0.1237 0.2358 0.6308
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.002 0.0059
Giardia lamblia Beta tubulin 0.1652 0.316 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.011 0.0346
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0048 0.014
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0042 0.005 0.0156
Onchocerca volvulus 0.005 0.0065 0.0646
Loa Loa (eye worm) patched family protein 0.005 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.0062 0.0088 0.0277
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0021 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0151 0.0261 0.0822

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.1836 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.7308 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 56.2341 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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