TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 388.462 | Formula: C23H24N4O2
H donors: 1 H acceptors: 2 LogP: 4.6 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: N#CNc1nccn1C[C@H](c1ccc(c(c1)OC1Cc2c(C1)cccc2)OC)C
InChi: 1S/C23H24N4O2/c1-16(14-27-10-9-25-23(27)26-15-24)17-7-8-21(28-2)22(13-17)29-20-11-18-5-3-4-6-19(18)12-20/h3-10,13,16,20H,11-12,14H2,1-2H3,(H,25,26)/t16-/m1/s1
InChiKey: ISVRFRJMIDSUOC-MRXNPFEDSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	phosphodiesterase 4B, cAMP-specific	Starlite/ChEMBL	References
Rattus norvegicus	Phosphodiesterase 4	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma japonicum	IPR002073,3'5'-cyclic nucleotide phosphodiesterase,domain-containing	Get druggable targets OG5_128242	All targets in OG5_128242
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	Get druggable targets OG5_128242	All targets in OG5_128242
Giardia lamblia	CAMP-specific 3,5-cyclic phosphodiesterase 4B	Get druggable targets OG5_128242	All targets in OG5_128242
Schistosoma japonicum	cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative	Get druggable targets OG5_128242	All targets in OG5_128242
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	Get druggable targets OG5_128242	All targets in OG5_128242
Cryptosporidium hominis	hypothetical protein	Get druggable targets OG5_128242	All targets in OG5_128242
Loa Loa (eye worm)	cyclic AMP specific phosphodiesterase PDE4D5A	Get druggable targets OG5_128242	All targets in OG5_128242
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	Get druggable targets OG5_128242	All targets in OG5_128242
Schistosoma japonicum	cAMP-specific 3',5'-cyclic phosphodiesterase 4C, putative	Get druggable targets OG5_128242	All targets in OG5_128242
Cryptosporidium parvum	membrane associated HD superfamily cyclic nucleotide phosphodiesterase domain containing protein	Get druggable targets OG5_128242	All targets in OG5_128242
Schistosoma japonicum	cAMP-specific 3',5'-cyclic phosphodiesterase, isoform F, putative	Get druggable targets OG5_128242	All targets in OG5_128242
Neospora caninum	cAMP-specific phosphodiesterase, putative	Get druggable targets OG5_128242	All targets in OG5_128242
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128242	All targets in OG5_128242
Brugia malayi	Probable 3',5'-cyclic phosphodiesterase R153.1, putative	Get druggable targets OG5_128242	All targets in OG5_128242
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	Get druggable targets OG5_128242	All targets in OG5_128242
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	Get druggable targets OG5_128242	All targets in OG5_128242
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	Get druggable targets OG5_128242	All targets in OG5_128242
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	Get druggable targets OG5_128242	All targets in OG5_128242
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	Get druggable targets OG5_128242	All targets in OG5_128242
Schistosoma japonicum	cAMP-specific 3',5'-cyclic phosphodiesterase 4D, putative	Get druggable targets OG5_128242	All targets in OG5_128242

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	Phosphodiesterase 4	536 aa	456 aa	27.2 %
Onchocerca volvulus	SH3 domain-binding glutamic acid-rich protein homolog	Phosphodiesterase 4	536 aa	527 aa	52.6 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	acetylcholinesterase	0.054	0.2848	0.2942
Mycobacterium tuberculosis	P-hydroxybenzoyl-AMP ligase FadD22	0.008	0.0298	0.0137
Loa Loa (eye worm)	hypothetical protein	0.008	0.0298	0.0296
Schistosoma mansoni	cell adhesion molecule	0.0028	0.0008	0.0009
Echinococcus multilocularis	BC026374 protein (S09 family)	0.0091	0.0358	0.037
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0091	0.0358	0.02
Toxoplasma gondii	propionate-CoA ligase	0.008	0.0298	0.2719
Echinococcus granulosus	carboxylesterase 5A	0.054	0.2848	0.2942
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0223	0.109	1
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0027	0.0002	0.0003
Giardia lamblia	CAMP-specific 3,5-cyclic phosphodiesterase 4B	0.0223	0.109	1
Entamoeba histolytica	acyl-CoA synthetase, putative	0.008	0.0298	0.5
Schistosoma mansoni	neuroligin 3 (S09 family)	0.0091	0.0358	0.037
Onchocerca volvulus		0.0316	0.1604	0.9696
Trichomonas vaginalis	spcc417.12 protein, putative	0.0091	0.0358	1
Brugia malayi	AMP-binding enzyme family protein	0.008	0.0298	0.0296
Echinococcus granulosus	long chain fatty acid transport protein 4	0.1772	0.9682	1
Trypanosoma cruzi	acetyl-CoA synthetase, putative	0.008	0.0298	0.0306
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0091	0.0358	0.037
Onchocerca volvulus	Tyrosine kinase homolog	0.0323	0.1645	1
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0358	0.0356
Mycobacterium tuberculosis	Peptide synthetase MbtE (peptide synthase)	0.008	0.0298	0.0137
Trypanosoma cruzi	fatty acid transporter protein-like, putative	0.1772	0.9682	1
Schistosoma mansoni	high-affinity cgmp-specific 35-cyclic phosphodiesterase	0.0027	0.0002	0.0003
Echinococcus multilocularis	calcium:calmodulin dependent 3',5' cyclic	0.0027	0.0002	0.0003
Brugia malayi	acetyl-Coenzyme A synthetase 2	0.008	0.0298	0.0296
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0028	0.0008	0.0009
Brugia malayi	AMP-binding enzyme family protein	0.008	0.0298	0.0296
Leishmania major	acetyl-CoA synthetase, putative	0.008	0.0298	0.031
Onchocerca volvulus		0.0091	0.0358	0.0443
Loa Loa (eye worm)	oxidoreductase	0.008	0.0298	0.0296
Leishmania major	4-coumarate:coa ligase-like protein	0.008	0.0298	0.031
Entamoeba histolytica	long-chain-fatty-acid--CoA ligase, putative	0.008	0.0298	0.5
Brugia malayi	Probable 3',5'-cyclic phosphodiesterase R153.1, putative	0.0196	0.094	0.0937
Onchocerca volvulus		0.0091	0.0358	0.0443
Leishmania major	acetyl-CoA synthetase, putative	0.008	0.0298	0.031
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0091	0.0358	0.037
Trypanosoma cruzi	long-chain-fatty-acid-CoA ligase, putative	0.008	0.0298	0.0306
Trichomonas vaginalis	antibiotic synthetase, putative	0.008	0.0298	0.832
Echinococcus granulosus	para nitrobenzyl esterase	0.0091	0.0358	0.037
Toxoplasma gondii	Acetyl-coenzyme A synthetase 2, putative	0.008	0.0298	0.2719
Loa Loa (eye worm)	hypothetical protein	0.008	0.0298	0.0296
Mycobacterium tuberculosis	Phenyloxazoline synthase MbtB (phenyloxazoline synthetase)	0.008	0.0298	0.0137
Loa Loa (eye worm)	hypothetical protein	0.008	0.0298	0.0296
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	0.0223	0.109	0.1126
Echinococcus multilocularis	calcium:calmodulin dependent 3',5' cyclic	0.0027	0.0002	0.0003
Loa Loa (eye worm)	carboxylesterase	0.0091	0.0358	0.0356
Leishmania major	long-chain-fatty-acid-CoA ligase, putative	0.008	0.0298	0.031
Mycobacterium tuberculosis	Probable peptide synthetase Nrp (peptide synthase)	0.008	0.0298	0.0137
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0346	0.1771	0.1769
Mycobacterium tuberculosis	Carboxylesterase LipT	0.0091	0.0358	0.02
Mycobacterium tuberculosis	Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase)	0.008	0.0298	0.0137
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0358	0.0356
Toxoplasma gondii	AMP-binding enzyme domain-containing protein	0.008	0.0298	0.2719
Trichomonas vaginalis	carboxylesterase domain containing protein, putative	0.0091	0.0358	1
Schistosoma mansoni	high-affinity cgmp-specific 35-cyclic phosphodiesterase	0.0027	0.0002	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0008	0.0006
Loa Loa (eye worm)	acetylcholinesterase 1	0.054	0.2848	0.2846
Echinococcus multilocularis	long chain fatty acid transport protein 4	0.1772	0.9682	1
Schistosoma mansoni	gliotactin	0.0091	0.0358	0.037
Brugia malayi	Carboxylesterase family protein	0.0091	0.0358	0.0356
Schistosoma mansoni	cgmp-dependent 35-cyclic phosphodiesterase	0.0027	0.0002	0.0003
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.1749	0.9553	1
Schistosoma mansoni	calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase	0.0027	0.0002	0.0003
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0027	0.0002	0.0003
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	0.0196	0.094	0.097
Brugia malayi	Carboxylesterase family protein	0.0091	0.0358	0.0356
Brugia malayi	Carboxylesterase family protein	0.0091	0.0358	0.0356
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0223	0.109	0.1126
Echinococcus multilocularis	acetylcholinesterase	0.054	0.2848	0.2942
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.008	0.0298	0.0296
Mycobacterium tuberculosis	Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase	0.008	0.0298	0.0137
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.008	0.0298	0.0137
Loa Loa (eye worm)	cyclic AMP specific phosphodiesterase PDE4D5A	0.0196	0.094	0.0937
Loa Loa (eye worm)	hypothetical protein	0.054	0.2848	0.2846
Echinococcus multilocularis	high affinity cAMP specific 3',5' cyclic	0.0027	0.0002	0.0003
Schistosoma mansoni	camp-specific cyclic nucleotide phosphodiesterase	0.0027	0.0002	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0358	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0358	0.0356
Onchocerca volvulus		0.0091	0.0358	0.0443
Schistosoma mansoni	acetylcholinesterase	0.0091	0.0358	0.037
Echinococcus granulosus	BC026374 protein S09 family	0.0091	0.0358	0.037
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0358	0.0356
Echinococcus granulosus	high affinity cgmp specific 3' 5' cyclic	0.0027	0.0002	0.0003
Trypanosoma brucei	long-chain-fatty-acid-CoA ligase, putative	0.008	0.0298	1
Loa Loa (eye worm)	hypothetical protein	0.054	0.2848	0.2846
Echinococcus granulosus	family S9 non peptidase ue S09 family	0.0091	0.0358	0.037
Echinococcus multilocularis	cAMP and cAMP inhibited cGMP 3',5' cyclic	0.0027	0.0002	0.0003
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	0.0223	0.109	0.1126
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0346	0.1771	0.1769
Echinococcus multilocularis	neuroligin	0.0091	0.0358	0.037
Mycobacterium ulcerans	long-chain-acyl-CoA synthetase	0.1829	1	1
Mycobacterium tuberculosis	Peptide synthetase MbtF (peptide synthase)	0.008	0.0298	0.0137
Trypanosoma cruzi	long-chain-fatty-acid-CoA ligase, putative	0.008	0.0298	0.0306
Echinococcus multilocularis	carboxylesterase 5A	0.054	0.2848	0.2942
Echinococcus granulosus	high affinity cAMP specific 3'5' cyclic	0.0027	0.0002	0.0003
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.008	0.0298	0.0296
Echinococcus granulosus	cAMP and cAMP inhibited cGMP 3'5' cyclic	0.0027	0.0002	0.0003
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.008	0.0298	0.0137
Echinococcus multilocularis	roundabout 2	0.0034	0.0039	0.004
Echinococcus multilocularis	acetylcholinesterase	0.054	0.2848	0.2942
Schistosoma mansoni	camp-specific 35-cyclic phosphodiesterase	0.0027	0.0002	0.0003
Mycobacterium tuberculosis	Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.008	0.0298	0.0137
Plasmodium vivax	acetyl-CoA synthetase, putative	0.008	0.0298	1
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.008	0.0298	0.0137
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.1829	1	1
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0039	0.0036
Brugia malayi	AMP-binding enzyme family protein	0.008	0.0298	0.0296
Leishmania major	4-coumarate:coa ligase-like protein	0.008	0.0298	0.031
Trypanosoma cruzi	fatty acid transporter protein-like, putative	0.1772	0.9682	1
Entamoeba histolytica	acyl-coA synthetase, putative	0.008	0.0298	0.5
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0358	0.0356
Mycobacterium leprae	possible long-chain acyl-CoA synthase	0.1749	0.9553	1
Loa Loa (eye worm)	carboxylesterase	0.054	0.2848	0.2846
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	0.0196	0.094	0.097
Brugia malayi	AMP-binding enzyme family protein	0.008	0.0298	0.0296
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0358	0.0356
Schistosoma mansoni	camp/cgmp cyclic nucleotide phosphodiesterase	0.0027	0.0002	0.0003
Loa Loa (eye worm)	hypothetical protein	0.008	0.0298	0.0296
Brugia malayi	AMP-binding enzyme family protein	0.008	0.0298	0.0296
Onchocerca volvulus		0.0091	0.0358	0.0443
Echinococcus granulosus	dual 3'5' cyclic AMP and GMP phosphodiesterase	0.0027	0.0002	0.0003
Brugia malayi	AMP-binding enzyme family protein	0.008	0.0298	0.0296
Brugia malayi	Carboxylesterase family protein	0.054	0.2848	0.2846
Trypanosoma brucei	acetyl-CoA synthetase, putative	0.008	0.0298	1
Schistosoma mansoni	FFA transport protein	0.1772	0.9682	1
Echinococcus granulosus	acetyl coenzyme A synthetase cytoplasmic	0.008	0.0298	0.0308
Brugia malayi	Carboxylesterase family protein	0.054	0.2848	0.2846
Leishmania major	4-coumarate:coa ligase-like protein	0.008	0.0298	0.031
Mycobacterium ulcerans	carboxylesterase, LipT	0.0091	0.0358	0.0062
Entamoeba histolytica	acyl-CoA synthetase, putative	0.008	0.0298	0.5
Onchocerca volvulus		0.0091	0.0358	0.0443
Schistosoma mansoni	acetyl-CoA synthetase	0.008	0.0298	0.0308
Schistosoma mansoni	high-affinity cgmp-specific 35-cyclic phosphodiesterase	0.0027	0.0002	0.0003
Echinococcus multilocularis	cAMP specific 3',5' cyclic phosphodiesterase	0.0223	0.109	0.1126
Loa Loa (eye worm)	carboxylesterase	0.0091	0.0358	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0039	0.0036
Schistosoma mansoni	BC026374 protein (S09 family)	0.0091	0.0358	0.037
Echinococcus granulosus	calcium:calmodulin dependent 3'5' cyclic	0.0027	0.0002	0.0003
Echinococcus granulosus	cAMP specific 3'5' cyclic phosphodiesterase	0.0223	0.109	0.1126
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.008	0.0298	0.0137
Echinococcus multilocularis	family S9 non peptidase ue (S09 family)	0.0091	0.0358	0.037
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0091	0.0358	0.037
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.054	0.2848	0.2942
Echinococcus multilocularis	dual 3',5' cyclic AMP and GMP phosphodiesterase	0.0027	0.0002	0.0003
Echinococcus multilocularis	high affinity cgmp specific 3' 5' cyclic	0.0027	0.0002	0.0003
Echinococcus granulosus	roundabout 2	0.0034	0.0039	0.004
Brugia malayi	Carboxylesterase family protein	0.0091	0.0358	0.0356
Echinococcus multilocularis	acetyl coenzyme A synthetase, cytoplasmic	0.008	0.0298	0.0308
Trichomonas vaginalis	antibiotic synthetase, putative	0.008	0.0298	0.832
Trypanosoma cruzi	acetyl-CoA synthetase, putative	0.008	0.0298	0.0306
Loa Loa (eye worm)	hypothetical protein	0.0223	0.109	0.1088
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.008	0.0298	0.0137
Loa Loa (eye worm)	hypothetical protein	0.008	0.0298	0.0296
Brugia malayi	hypothetical protein	0.0091	0.0358	0.0356
Echinococcus multilocularis	para nitrobenzyl esterase	0.0091	0.0358	0.037
Echinococcus granulosus	neuroligin	0.0091	0.0358	0.037
Plasmodium falciparum	acetyl-CoA synthetase, putative	0.008	0.0298	1
Echinococcus granulosus	calcium:calmodulin dependent 3'5' cyclic	0.0027	0.0002	0.0003
Leishmania major	fatty acid transporter protein-like protein	0.1749	0.9553	1
Mycobacterium tuberculosis	POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT)	0.0091	0.0358	0.02
Echinococcus granulosus	acetylcholinesterase	0.054	0.2848	0.2942

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 0.057 uM	Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes	ChEMBL.	11844693
Inhibition (functional)	= 54 %	Evaluated for antiinflammatory activity in the TPA induced ear inflammation model at a dose 1 mg/kg (25 ug)	ChEMBL.	11844693
Ki (binding)	= 220 nM	Displacement of [3H]-rolipram from rat forebrain membrane	ChEMBL.	11844693

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1788264

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1518133