Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | allatostatin A receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | thymidylate synthase | 0.2067 | 0.1798 | 0.1798 |
Schistosoma mansoni | opsin-like receptor | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | sulfakinin receptor protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | hypothetical protein | 0.0983 | 0.083 | 0.083 |
Echinococcus multilocularis | neuropeptide receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | g protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0221 | 0.0149 | 0.0126 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.7888 | 0.6996 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | neuropeptide F receptor | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | neuropeptide receptor | 0.0221 | 0.0149 | 0.0132 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0983 | 0.083 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | opsin-like receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | fmrfamide receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | sex peptide receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | neuropeptide F receptor | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | dihydrofolate reductase | 1.1251 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | Dopamine receptor | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | amine GPCR | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | g protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | opsin-like receptor | 0.0221 | 0.0149 | 0.0126 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | GnHR receptor homolog | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | G protein-coupled receptor | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | serotonin receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | hypothetical protein | 0.0221 | 0.0149 | 0.0126 |
Schistosoma mansoni | amine GPCR | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | somatostatin receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | orexin receptor type 2 | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | thymidylate synthase | 0.2067 | 0.1798 | 0.1784 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | Dopamine receptor protein 1 | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | Serotonin receptor | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | hypothetical protein | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | amine GPCR | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0221 | 0.0149 | 0.0126 |
Schistosoma mansoni | amine GPCR | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | sex peptide receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | follicle stimulating hormone receptor | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.2067 | 0.1798 | 0.1055 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0114 | 0.0054 | 0.0054 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0221 | 0.0149 | 0.0126 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0221 | 0.0149 | 0.0126 |
Brugia malayi | putative neuropeptide receptor | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | neuropeptide receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | g protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | neuropeptide s receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | neuropeptide receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | serotonin receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | Cytochrome P450 family protein | 0.0114 | 0.0054 | 0.0054 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0221 | 0.0149 | 0.0132 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 1.1251 | 1 | 1 |
Echinococcus multilocularis | dihydrofolate reductase | 1.1251 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0221 | 0.0149 | 0.0126 |
Schistosoma mansoni | biogenic amine receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | amine GPCR | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | RE15519p | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | G-protein coupled receptor | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | neuropeptide receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | G-protein coupled receptor | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | Dihydrofolate reductase | 1.1251 | 1 | 1 |
Brugia malayi | AKH receptor | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | fmrfamide receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | thymidylate synthase | 0.2067 | 0.1798 | 0.1798 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0221 | 0.0149 | 0.0126 |
Onchocerca volvulus | 0.2067 | 0.1798 | 1 | |
Schistosoma mansoni | myosin xvIII | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0073 | 0.0017 | 0.0017 |
Echinococcus multilocularis | g protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0073 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | allatostatin A receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0221 | 0.0149 | 0.0126 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | somatostatin receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | larval opioid receptor | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0221 | 0.0149 | 0.0132 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 1.1251 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | biogenic amine receptor | 0.0221 | 0.0149 | 0.0126 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.7888 | 0.6996 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | neuropeptide receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | hypothetical protein | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | neuropeptide receptor | 0.0221 | 0.0149 | 0.0126 |
Mycobacterium ulcerans | thymidylate synthase | 0.2067 | 0.1798 | 0.1798 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.7888 | 0.6996 | 1 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.7888 | 0.6996 | 0.5 |
Echinococcus granulosus | dihydrofolate reductase | 1.1251 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0221 | 0.0149 | 0.0132 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7888 | 0.6996 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0221 | 0.0149 | 0.0132 |
Chlamydia trachomatis | dihydrofolate reductase | 1.1251 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Echinococcus multilocularis | serotonin receptor | 0.0221 | 0.0149 | 0.0132 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0983 | 0.083 | 0.1186 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0221 | 0.0149 | 0.0132 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | Melatonin receptor type 1A | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | adenoreceptor | 0.0221 | 0.0149 | 0.0126 |
Echinococcus granulosus | g-protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | neuropeptide receptor | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | thymidylate synthase | 0.2067 | 0.1798 | 0.1784 |
Echinococcus multilocularis | g protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | histamine h1 receptor | 0.0221 | 0.0149 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | ORL1-like opioid receptor | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | Serotonin receptor | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0221 | 0.0149 | 0.0126 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7888 | 0.6996 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0221 | 0.0149 | 0.0132 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0221 | 0.0149 | 0.0149 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0221 | 0.0149 | 0.0132 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0221 | 0.0149 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0221 | 0.0149 | 0.0149 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.2067 | 0.1798 | 0.1779 |
Schistosoma mansoni | dihydrofolate reductase | 1.1251 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0221 | 0.0149 | 0.0126 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 1.1251 | 1 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0221 | 0.0149 | 0.0149 |
Brugia malayi | Dopamine receptor protein 2 | 0.0221 | 0.0149 | 0.0149 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Cleavage rate (functional) | = 32.4 uM min-1 g-1 | Intracellular cleavage of the compound exhibited in Candida albicans ATCC 26278 | ChEMBL. | 2120441 |
Cleavage rate (functional) | = 32.4 uM min-1 g-1 | Intracellular cleavage of the compound exhibited in Candida albicans ATCC 26278 | ChEMBL. | 2120441 |
MIC (functional) | = 0.25 ug ml-1 | In vitro antimicrobial activity of the compound against Bacillus pumilis CCM 1697 | ChEMBL. | 2120441 |
MIC (functional) | = 1 ug ml-1 | In vitro antimicrobial activity of the compound against Staphylococcus aureus 163J | ChEMBL. | 2120441 |
MIC (functional) | = 2 ug ml-1 | In vitro antimicrobial activity of the compound against Cornyebacterium sp. 239 | ChEMBL. | 2120441 |
MIC (functional) | = 4 ug ml-1 | In vitro antimicrobial activity of the compound against Staphylococcus epidermis 154J | ChEMBL. | 2120441 |
MIC (functional) | = 4 ug ml-1 | In vitro antimicrobial activity of the compound against Streptococcus beta-haemolyticus A 800 | ChEMBL. | 2120441 |
MIC (functional) | = 7.5 ug ml-1 | In vitro antifungal activity of the compound against Trychophyton nanum | ChEMBL. | 2120441 |
MIC (functional) | = 8 ug ml-1 | In vitro antimicrobial activity of the compound against Streptococcus faecalis CCM 1875 | ChEMBL. | 2120441 |
MIC (functional) | = 10 ug ml-1 | In vitro antifungal activity of the compound against Candida albicans 4477 | ChEMBL. | 2120441 |
MIC (functional) | = 10 ug ml-1 | In vitro antifungal activity of the compound against Candida albicans 4477 | ChEMBL. | 2120441 |
MIC (functional) | = 12.5 ug ml-1 | In vitro antifungal activity of the compound against Candida tropicalis | ChEMBL. | 2120441 |
MIC (functional) | = 15 ug ml-1 | In vitro antifungal activity of the compound against Geotrichum candidum | ChEMBL. | 2120441 |
MIC (functional) | = 16 ug ml-1 | In vitro antimicrobial activity of the compound against Microsporum luteus NCTC 2665 | ChEMBL. | 2120441 |
MIC (functional) | > 50 ug ml-1 | In vitro antifungal activity of the compound against Rhizopus arrhizus | ChEMBL. | 2120441 |
MIC (functional) | > 50 ug ml-1 | In vitro antifungal activity of the compound against Aspergillus nidulans 590 | ChEMBL. | 2120441 |
Transport rate (functional) | = 1.3 uM min-1 g-1 | Rate of transport of compound in Candida albicans ATCC 26278 | ChEMBL. | 2120441 |
Transport rate (functional) | = 1.3 uM min-1 g-1 | Rate of transport of compound in Candida albicans ATCC 26278 | ChEMBL. | 2120441 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.