Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Onchocerca volvulus | 0.0273 | 1 | 1 | |
Echinococcus multilocularis | peroxidasin | 0.0273 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0273 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0273 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0273 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0273 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0273 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0273 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0273 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0273 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0273 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0273 | 1 | 1 |
Onchocerca volvulus | 0.0273 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0273 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0273 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0273 | 1 | 1 |
Onchocerca volvulus | 0.0273 | 1 | 1 | |
Giardia lamblia | High cysteine protein | 0.005 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Toxoplasma gondii | EGF family domain-containing protein | 0.005 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 1.2589 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.