Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 1 | 1 |
Onchocerca volvulus | 0.0077 | 1 | 0.5 | |
Onchocerca volvulus | Peroxidase homolog | 0.0077 | 1 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 1 | 1 |
Onchocerca volvulus | 0.0077 | 1 | 0.5 | |
Schistosoma mansoni | peroxidasin | 0.0077 | 1 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0077 | 1 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0077 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0077 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0077 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0077 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0077 | 1 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0077 | 1 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 1 | 1 |
Onchocerca volvulus | 0.0077 | 1 | 0.5 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0077 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0077 | 1 | 0.5 |
Brugia malayi | Peroxidasin | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 1 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0077 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0077 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 25835 after 24 hrs by twofold serial dilution method | ChEMBL. | 21316819 |
MIC (functional) | = 50 ug ml-1 | Antifungal activity against Cryptococcus neoformans after 72 to 96 hrs by twofold serial dilution method | ChEMBL. | 21316819 |
MIC (functional) | = 200 ug ml-1 | Antifungal activity against Candida albicans after 24 hrs by twofold serial dilution method | ChEMBL. | 21316819 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.