Detailed information for compound 1522846

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 451.505 | Formula: C22H24F3N3O2S
  • H donors: 0 H acceptors: 2 LogP: 4.13 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN1CCN(CC1)Cc1ccc2c(c1)ccn2S(=O)(=O)c1cccc(c1)C(F)(F)F
  • InChi: 1S/C22H24F3N3O2S/c1-2-26-10-12-27(13-11-26)16-17-6-7-21-18(14-17)8-9-28(21)31(29,30)20-5-3-4-19(15-20)22(23,24)25/h3-9,14-15H,2,10-13,16H2,1H3
  • InChiKey: GZJJDWANDMGTPQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_145685 All targets in OG5_145685
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_145685 All targets in OG5_145685
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei I/6 autoantigen 0.0123 0.0292 0.0965
Echinococcus multilocularis dna polymerase kappa 0.002 0.0012 0.0019
Plasmodium vivax serine-repeat antigen (SERA) 0.0195 0.0486 0.211
Toxoplasma gondii microneme protein MIC17B 0.003 0.0041 0.0041
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0029 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0136 0.024
Schistosoma mansoni histamine h1 receptor 0.0026 0.003 0.0028
Onchocerca volvulus 0.0062 0.0127 0.0426
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0195 0.0486 0.2194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0057
Echinococcus multilocularis G protein coupled receptor 139 0.0026 0.003 0.0052
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0123 0.0292 0.129
Echinococcus granulosus glycoprotein Antigen 5 0.0055 0.0107 0.0196
Onchocerca volvulus 0.0055 0.0107 0.0352
Leishmania major hypothetical protein, conserved 0.0211 0.0529 0.1785
Loa Loa (eye worm) programmed cell death protein 6 0.0126 0.03 0.0577
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0211 0.0529 0.1785
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0123 0.0292 0.0543
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.003 0.0052
Trypanosoma cruzi centrin, putative 0.015 0.0365 0.0685
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0021 0.0036
Onchocerca volvulus 0.0055 0.0107 0.0354
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0163 0.03
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.003 0.0052
Onchocerca volvulus 0.082 0.2179 0.7834
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0195 0.0486 0.0484
Onchocerca volvulus 0.0027 0.0032 0.0081
Brugia malayi calpain family protein 1 0.1863 0.5006 0.9691
Loa Loa (eye worm) hypothetical protein 0.0046 0.0083 0.0156
Mycobacterium ulcerans hypothetical protein 0.0037 0.0058 0.4878
Onchocerca volvulus 0.0031 0.0043 0.0122
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Leishmania major centrin, putative 0.0123 0.0292 0.0965
Brugia malayi Pre-SET motif family protein 0.0061 0.0125 0.0238
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1089 0.2909 1
Brugia malayi Trypsin family protein 0.0055 0.0107 0.0203
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Brugia malayi calcium-binding protein 0.0123 0.0292 0.0561
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.003 0.0028
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0195 0.0486 0.211
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0005 0.0003
Leishmania major DNA polymerase eta, putative 0.0046 0.0083 0.0244
Brugia malayi Papain family cysteine protease containing protein 0.082 0.2179 0.4216
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0822 0.2186 0.7503
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0854 0.2271 0.7797
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0553 0.1456 0.4983
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0195 0.0486 0.211
Echinococcus granulosus calumenin 0.0126 0.03 0.0557
Brugia malayi chromobox protein homolog 3 0.004 0.0066 0.0125
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0195 0.0486 0.211
Echinococcus granulosus intermediate filament protein 0.0055 0.0107 0.0197
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0061
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0556 0.1464 0.2817
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0075 0.0342
Brugia malayi AKH receptor 0.0026 0.003 0.0053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1089 0.2909 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1089 0.2909 0.5621
Schistosoma mansoni hypothetical protein 0.0062 0.0127 0.0125
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0195 0.0486 0.211
Plasmodium vivax glutathione reductase, putative 0.0101 0.0233 0.0936
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.012 0.041
Trypanosoma cruzi centrin, putative 0.015 0.0365 0.0685
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0553 0.1456 0.2801
Schistosoma mansoni neuronal calcium sensor 0.0123 0.0292 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0253 0.0645 0.1245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.0486 0.2232
Trypanosoma brucei caltractin, putative 0.015 0.0365 0.1218
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0136 0.0259
Onchocerca volvulus Arrow homolog 0.0026 0.0029 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0898 0.239 0.8209
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0109
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0448 0.1172 0.2252
Loa Loa (eye worm) calpain family protein 1 0.1383 0.3705 0.7171
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0018 0.0029
Brugia malayi Pre-SET motif family protein 0.0424 0.1108 0.2142
Echinococcus multilocularis cathepsin l cysteine peptidase 0.082 0.2179 0.4072
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.003 0.0052
Trichomonas vaginalis myosin light chain 1, putative 0.0123 0.0292 0.1338
Loa Loa (eye worm) hypothetical protein 0.0153 0.0373 0.0719
Trypanosoma brucei calpain, putative 0.0609 0.1608 0.551
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0053 0.0098
Plasmodium falciparum centrin-1 0.0123 0.0292 0.1296
Toxoplasma gondii PAN domain-containing protein 0.003 0.0041 0.0041
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0058 0.0056
Trypanosoma cruzi cysteine proteinase, putative 0.0448 0.1172 0.2252
Echinococcus multilocularis neuropeptide receptor 0.0026 0.003 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Schistosoma mansoni cathepsin D (A01 family) 0.0584 0.1541 0.1539
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0195 0.0486 0.0938
Onchocerca volvulus 0.082 0.2179 0.7834
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0129 0.0307 0.0571
Trypanosoma brucei Calpain-like protein 1.2 0.0699 0.1852 0.6352
Onchocerca volvulus 0.003 0.0041 0.0113
Mycobacterium leprae Probable lipase LipE 0.0037 0.0058 0.043
Schistosoma mansoni neuropeptide f receptor 76f 0.0026 0.003 0.0028
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Echinococcus multilocularis calpain 5 0.0822 0.2186 0.4085
Entamoeba histolytica cysteine proteinase, putative 0.0566 0.1493 0.6833
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0308 0.0792 0.2694
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Echinococcus multilocularis calpain 7 (C02 family) 0.0822 0.2186 0.4085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Loa Loa (eye worm) fibroinase 0.082 0.2179 0.4216
Entamoeba histolytica prefoldin subunit 6, putative 0.0062 0.0127 0.053
Echinococcus granulosus transmembrane protease serine 3 0.0055 0.0107 0.0196
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0123 0.0292 0.0561
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0012 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.003 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0534 0.1406 0.4813
Trypanosoma brucei centrin, putative 0.0123 0.0292 0.0965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0012 0.0055
Leishmania major cathepsin L-like protease 0.1012 0.2699 0.9274
Leishmania major calpain protease-like protein 0.0342 0.0885 0.3013
Brugia malayi Cathepsin L-like precursor 0.082 0.2179 0.4216
Brugia malayi cathepsin Z-like cysteine proteinase 0.0195 0.0486 0.0938
Schistosoma mansoni hypothetical protein 0.0123 0.0292 0.029
Trypanosoma cruzi small myristoylated protein 1-1 0.0363 0.0943 0.1806
Echinococcus granulosus g-protein coupled receptor 0.0026 0.003 0.0052
Entamoeba histolytica hypothetical protein 0.0195 0.0486 0.2189
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0125 0.0434
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0211 0.0529 0.1785
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0342 0.0885 0.4061
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0839 0.2232 0.4172
Brugia malayi Fibulin-1 precursor 0.0028 0.0033 0.0061
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0195 0.0486 0.2468
Schistosoma mansoni hypothetical protein 0.0065 0.0136 0.0133
Leishmania major receptor-type adenylate cyclase a-like protein 0.0211 0.0529 0.1785
Echinococcus granulosus neuropeptide s receptor 0.0026 0.003 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.0486 0.2232
Trichomonas vaginalis conserved hypothetical protein 0.0195 0.0486 0.2232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0009 0.0039
Echinococcus multilocularis EF hand domain containing family member A2 0.0123 0.0292 0.0542
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0211 0.0529 0.1003
Schistosoma mansoni intermediate filament proteins 0.0055 0.0107 0.0105
Plasmodium falciparum plasmepsin VI 0.0209 0.0525 0.2374
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0079
Onchocerca volvulus 0.0123 0.0292 0.1019
Entamoeba histolytica cysteine protease, putative 0.0195 0.0486 0.2189
Loa Loa (eye worm) hypothetical protein 0.0051 0.0096 0.0182
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0004 0.0002
Entamoeba histolytica cysteine proteinase 2 0.0448 0.1172 0.5356
Brugia malayi hypothetical protein 0.0153 0.0373 0.0719
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0098 0.0167
Toxoplasma gondii cathepsin CPC2 0.0195 0.0486 0.2117
Brugia malayi Smad1 0.0017 0.0004 0.0003
Onchocerca volvulus 0.0026 0.003 0.0073
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0822 0.2186 0.4218
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0267 0.0682 0.2312
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.047 0.1233 0.2368
Entamoeba histolytica cysteine proteinase, putative 0.0448 0.1172 0.5356
Giardia lamblia Hypothetical protein 0.0062 0.0127 0.0598
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1245
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0027 0.0031 0.0057
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0029 0.0053
Plasmodium falciparum plasmepsin I 0.0209 0.0525 0.2374
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0038 0.007
Brugia malayi Myosin regulatory light chain 1 0.0027 0.0032 0.0057
Trichomonas vaginalis calmodulin, putative 0.0123 0.0292 0.1338
Trypanosoma brucei centrin, putative 0.0123 0.0292 0.0965
Loa Loa (eye worm) hypothetical protein 0.1383 0.3705 0.7171
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0794 0.2108 0.7235
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0854 0.2271 0.7797
Loa Loa (eye worm) matrixin family protein 0.0053 0.0103 0.0196
Echinococcus multilocularis centrin 2 0.0123 0.0292 0.0542
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0058 0.0719
Echinococcus granulosus alpha 1A adrenergic receptor 0.0026 0.003 0.0052
Echinococcus granulosus somatostatin receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0053
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0058 0.043
Loa Loa (eye worm) hypothetical protein 0.0062 0.0127 0.0242
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.003 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0127 0.0583
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0032 0.003
Schistosoma mansoni neuronal calcium sensor 0.0123 0.0292 0.029
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0012 0.0019
Trypanosoma cruzi trypanothione reductase, putative 0.0101 0.0233 0.043
Giardia lamblia Cathepsin L precursor 0.0195 0.0486 0.2468
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0257 0.0656 1
Brugia malayi hypothetical protein 0.0062 0.0127 0.0242
Toxoplasma gondii calmodulin CAM1 0.0126 0.03 0.1249
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0126 0.03 0.0559
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0054 0.5
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0163 0.03
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0209 0.0525 0.0979
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.0054 0.02
Echinococcus granulosus tm gpcr rhodopsin 0.1026 0.2738 0.5119
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0109
Echinococcus granulosus neuropeptide FF receptor 2 0.0026 0.003 0.0052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0081
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Toxoplasma gondii hypothetical protein 0.0342 0.0885 0.3974
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0107 0.0105
Brugia malayi calpain 5 0.048 0.1259 0.2435
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0026 0.003 0.0052
Onchocerca volvulus 0.082 0.2179 0.7834
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Trypanosoma brucei hypothetical protein, conserved 0.0341 0.0883 0.3007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0107 0.0204
Echinococcus granulosus cathepsin b 0.1922 0.5166 0.966
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0058 0.0719
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0027 0.0032 0.0081
Schistosoma mansoni opsin-like receptor 0.0026 0.003 0.0028
Toxoplasma gondii EFHC1, putative 0.0123 0.0292 0.121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Brugia malayi Pepsin A precursor 0.0062 0.0127 0.0242
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Onchocerca volvulus 0.0153 0.0373 0.1315
Schistosoma mansoni mitochondrial solute carrier 0.0123 0.0292 0.029
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Echinococcus multilocularis tissue type plasminogen activator 0.0065 0.0136 0.025
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Schistosoma mansoni calmodulin 0.0123 0.0292 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1467 0.3931 0.735
Entamoeba histolytica calcium-binding protein, putative 0.0123 0.0292 0.129
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0195 0.0486 0.2189
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0267 0.0682 0.2312
Loa Loa (eye worm) matrixin family protein 0.0049 0.0091 0.0173
Schistosoma mansoni alpha-1 adrenergic receptor 0.0026 0.003 0.0028
Toxoplasma gondii troponin c, isotype gamma, putative 0.0123 0.0292 0.121
Schistosoma mansoni reticulocalbin 0.0123 0.0292 0.029
Brugia malayi cathepsin Z-like cysteine proteinase 0.0195 0.0486 0.0938
Echinococcus granulosus cathepsin l cysteine peptidase 0.082 0.2179 0.4072
Schistosoma mansoni calmodulin related calcium binding protein 0.0123 0.0292 0.029
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0122
Brugia malayi cathepsin F-like cysteine proteinase 0.0195 0.0486 0.0938
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0053
Brugia malayi Cathepsin L-like precursor 0.082 0.2179 0.4216
Echinococcus multilocularis programmed cell death protein 0.015 0.0365 0.0679
Trichomonas vaginalis calmodulin, putative 0.0123 0.0292 0.1338
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Onchocerca volvulus Matrilysin homolog 0.0049 0.0091 0.0296
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0195 0.0486 0.2194
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.003 0.0052
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1986 0.5339 0.9984
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Echinococcus multilocularis calbindin 32 0.0126 0.03 0.0557
Plasmodium vivax aspartyl protease, putative 0.0062 0.0127 0.0443
Echinococcus granulosus tar DNA binding protein 0.0061 0.0124 0.0229
Entamoeba histolytica grainin 2 0.0027 0.0032 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.1456 0.4983
Onchocerca volvulus 0.0126 0.03 0.105
Brugia malayi Matrixin family protein 0.0053 0.0103 0.0196
Schistosoma mansoni chromobox protein 0.0071 0.0151 0.0149
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0096 0.0182
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0058 0.0719
Echinococcus multilocularis thioredoxin glutathione reductase 0.0101 0.0233 0.0433
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0268
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0138 0.0136
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0027 0.0032 0.0081
Giardia lamblia Cysteine protease 0.0195 0.0486 0.2468
Leishmania major centrin, putative,caltractin, putative 0.0123 0.0292 0.0965
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Brugia malayi aspartic protease BmAsp-1, identical 0.0062 0.0127 0.0242
Leishmania major calpain family cysteine protease-like protein 0.0553 0.1456 0.4983
Brugia malayi glutathione reductase 0.0101 0.0233 0.0448
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0107 0.0105
Giardia lamblia Cathepsin B precursor 0.0729 0.1933 1
Plasmodium falciparum plasmepsin VII 0.0062 0.0127 0.0539
Echinococcus granulosus cathepsin L 0.0448 0.1172 0.219
Echinococcus granulosus cathepsin L cysteine protease 0.0448 0.1172 0.219
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Brugia malayi Serotonin receptor 0.0026 0.003 0.0053
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0046 0.0066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.0486 0.2232
Trypanosoma brucei DNA polymerase eta, putative 0.0046 0.0083 0.0244
Echinococcus multilocularis glycoprotein Antigen 5 0.0055 0.0107 0.0196
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0231 0.0586 0.8879
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0136 0.0259
Onchocerca volvulus Peroxidase homolog 0.0065 0.0136 0.0457
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0195 0.0486 0.0938
Trichomonas vaginalis calcium binding protein, putative 0.0027 0.0032 0.0146
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0534 0.1406 0.4813
Trypanosoma brucei small myristoylated protein 1-2 0.0363 0.0943 0.3213
Leishmania major hypothetical protein, conserved 0.0211 0.0529 0.1785
Loa Loa (eye worm) hypothetical protein 0.0195 0.0486 0.0938
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.0018 0.0016
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0107 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0566 0.1493 0.6851
Leishmania major phospholipase c-like protein 0.0123 0.0292 0.0965
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1015 0.2707 0.9303
Onchocerca volvulus 0.0027 0.0032 0.0081
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0534 0.1406 0.2706
Brugia malayi beta-lactamase family protein 0.0037 0.0058 0.0109
Schistosoma mansoni lamin 0.0055 0.0107 0.0105
Onchocerca volvulus Cathepsin L homolog 0.082 0.2179 0.7834
Echinococcus multilocularis cysteine protease 0.082 0.2179 0.4072
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0012 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Brugia malayi Muscleblind-like protein 0.0148 0.036 0.0693
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0125 0.023
Leishmania major cathepsin L-like protease 0.1012 0.2699 0.9274
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.0486 0.2232
Trypanosoma brucei Component of motile flagella 41 0.0123 0.0292 0.0965
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0195 0.0486 0.2232
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0029 0.0051
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.0054 0.0103
Trichomonas vaginalis caltractin, putative 0.0027 0.0032 0.0146
Loa Loa (eye worm) glutathione reductase 0.0101 0.0233 0.0448
Loa Loa (eye worm) papain family cysteine protease containing protein 0.082 0.2179 0.4216
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.003 0.0052
Entamoeba histolytica cysteine protease, putative 0.0195 0.0486 0.2189
Plasmodium vivax aspartyl proteinase, putative 0.0209 0.0525 0.2291
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.003 0.0053
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0096 0.0182
Plasmodium falciparum plasmepsin IX 0.0062 0.0127 0.0539
Leishmania major cathepsin L-like protease 0.082 0.2179 0.748
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0058 0.016
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0027 0.0031 0.0302
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0125 0.0123
Echinococcus granulosus neuronal calcium sensor 0.0123 0.0292 0.0542
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0195 0.0486 0.0484
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Plasmodium falciparum centrin-4 0.0027 0.0032 0.0098
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0258
Echinococcus multilocularis chromobox protein 1 0.0071 0.0151 0.0278
Trypanosoma brucei hypothetical protein, conserved 0.0123 0.0292 0.0965
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0136 0.0259
Leishmania major kinesin, putative 0.048 0.1259 0.4306
Leishmania major i/6 autoantigen-like protein 0.0123 0.0292 0.0965
Onchocerca volvulus 0.003 0.0041 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.003 0.0052
Loa Loa (eye worm) thioredoxin reductase 0.0101 0.0233 0.0448
Mycobacterium tuberculosis Probable reductase 0.0231 0.0586 0.8913
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0117 0.0215
Giardia lamblia Cathepsin L precursor 0.0195 0.0486 0.2468
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0125 0.023
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0729 0.1933 0.3728
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0012 0.001
Trypanosoma brucei centrin-3 0.015 0.0365 0.1218
Onchocerca volvulus Dual oxidase homolog 0.0065 0.0136 0.0457
Schistosoma mansoni cpg binding protein 0.003 0.004 0.0038
Toxoplasma gondii PAN domain-containing protein 0.003 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0195 0.0486 0.0938
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0211 0.0529 0.1003
Loa Loa (eye worm) MH2 domain-containing protein 0.0245 0.0623 0.1202
Leishmania major hypothetical protein, conserved 0.0051 0.0098 0.0297
Entamoeba histolytica grainin 2 0.015 0.0365 0.1628
Brugia malayi Hemopexin family protein 0.0031 0.0043 0.008
Brugia malayi Dopamine receptor protein 2 0.0026 0.003 0.0053
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.003 0.0028
Schistosoma mansoni neuronal calcium sensor 0.0123 0.0292 0.029
Giardia lamblia Cathepsin L precursor 0.0195 0.0486 0.2468
Onchocerca volvulus 0.0037 0.0058 0.0177
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.0054 0.0218
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0026 0.003 0.0053
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0026 0.003 0.0028
Brugia malayi Cytochrome P450 family protein 0.0034 0.005 0.0093
Echinococcus granulosus calcium uptake protein 1 0.0126 0.03 0.0557
Onchocerca volvulus Chorion peroxidase homolog 0.0065 0.0136 0.0457
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.0054 0.0081
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0058 0.0109
Plasmodium falciparum cysteine repeat modular protein 1 0.0065 0.0136 0.0577
Brugia malayi follicle stimulating hormone receptor 0.0026 0.003 0.0053
Plasmodium falciparum glutathione reductase 0.0101 0.0233 0.1028
Entamoeba histolytica cysteine proteinase, putative 0.0448 0.1172 0.5356
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0151 0.0693
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0058 0.0719
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0026 0.003 0.0052
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0231 0.0586 0.8913
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Brugia malayi Cathepsin L-like precursor 0.082 0.2179 0.4216
Onchocerca volvulus 0.0022 0.0018 0.0033
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0046 0.0065
Echinococcus granulosus neurocalcin 0.0123 0.0292 0.0542
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trypanosoma cruzi major cysteine proteinase, putative 0.0387 0.1006 0.1929
Trypanosoma brucei mitochondrial calcium uptake 1 0.0123 0.0292 0.0965
Brugia malayi calpain D 0.0342 0.0885 0.171
Echinococcus granulosus centrin 2 0.0123 0.0292 0.0542
Onchocerca volvulus 0.003 0.0041 0.0113
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0553 0.1456 0.2801
Brugia malayi hypothetical protein 0.0124 0.0296 0.0569
Schistosoma mansoni chromobox protein 0.0071 0.0151 0.0149
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0195 0.0486 0.2468
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0058 0.4878
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0027 0.0032 0.0146
Entamoeba histolytica cysteine protease, putative 0.0195 0.0486 0.2189
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Schistosoma mansoni myosin light chain 0.0027 0.0032 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0448 0.1172 0.5381
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.008 0.0176 0.0325
Schistosoma mansoni hypothetical protein 0.0026 0.003 0.0028
Schistosoma mansoni cathepsin D (A01 family) 0.0584 0.1541 0.1539
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0342 0.0885 0.4061
Loa Loa (eye worm) hypothetical protein 0.0051 0.0098 0.0186
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0209 0.0525 0.1013
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0292 0.1338
Echinococcus granulosus enteropeptidase 0.0055 0.0107 0.0196
Trichomonas vaginalis set domain proteins, putative 0.0483 0.1267 0.5814
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0211 0.0529 0.1785
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.0529 0.1003
Onchocerca volvulus 0.0195 0.0486 0.1722
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Schistosoma mansoni hypothetical protein 0.0026 0.003 0.0028
Brugia malayi Melatonin receptor type 1A 0.0026 0.003 0.0053
Echinococcus granulosus calpain A 0.0822 0.2186 0.4085
Loa Loa (eye worm) hypothetical protein 0.0056 0.0111 0.0212
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0729 0.1933 0.6633
Trypanosoma cruzi cysteine protease, putative 0.0448 0.1172 0.2252
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1922 0.5166 0.5165
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.016
Leishmania major small myristoylated protein-3, putative 0.0308 0.0792 0.2694
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.0054 0.0144
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0054 0.5
Echinococcus multilocularis dna polymerase eta 0.0046 0.0083 0.0151
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Echinococcus granulosus geminin 0.0346 0.0896 0.1672
Brugia malayi Cathepsin L-like precursor 0.0566 0.1493 0.2887
Echinococcus multilocularis muscleblind protein 1 0.0148 0.036 0.0669
Toxoplasma gondii EF hand domain-containing protein 0.0123 0.0292 0.121
Echinococcus multilocularis orexin receptor type 2 0.0026 0.003 0.0052
Schistosoma mansoni DNA polymerase eta 0.0046 0.0083 0.008
Brugia malayi Matrixin family protein 0.0022 0.0018 0.0032
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0123 0.0292 0.0543
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Plasmodium falciparum plasmepsin III 0.0062 0.0127 0.0539
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0129 0.0307 0.0571
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0026 0.003 0.0053
Brugia malayi hypothetical protein 0.0055 0.0107 0.0203
Schistosoma mansoni neuronal calcium sensor 0.0123 0.0292 0.029
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.0054 0.0144
Plasmodium vivax unspecified product 0.0195 0.0486 0.211
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Schistosoma mansoni egf-like domain protein 0.0026 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Entamoeba histolytica grainin, putative 0.0126 0.03 0.1329
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0195 0.0486 0.211
Echinococcus multilocularis cathepsin L cysteine protease 0.082 0.2179 0.4072
Schistosoma mansoni centrin-related 0.0123 0.0292 0.029
Echinococcus granulosus calpain 0.0822 0.2186 0.4085
Echinococcus multilocularis calmodulin 0.0123 0.0292 0.0542
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Entamoeba histolytica cysteine proteinase, putative 0.082 0.2179 1
Echinococcus multilocularis programmed cell death protein 6 0.003 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0195 0.0486 0.2232
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0534 0.1406 0.4813
Schistosoma mansoni cathepsin F (C01 family) 0.082 0.2179 0.2177
Echinococcus granulosus tissue type plasminogen activator 0.0065 0.0136 0.025
Echinococcus multilocularis calmodulin 0.0123 0.0292 0.0542
Onchocerca volvulus 0.0037 0.0058 0.0177
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0136 0.0259
Onchocerca volvulus 0.0026 0.003 0.0073
Loa Loa (eye worm) hypothetical protein 0.0566 0.1493 0.2887
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0469 0.0467
Trypanosoma brucei unspecified product 0.0211 0.0529 0.1785
Giardia lamblia Hypothetical protein 0.0126 0.03 0.1499
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0026 0.003 0.0053
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0107 0.0105
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0026 0.003 0.0052
Loa Loa (eye worm) calpain 5 0.048 0.1259 0.2435
Toxoplasma gondii hypothetical protein 0.003 0.0041 0.0041
Giardia lamblia Cysteine protease 0.0195 0.0486 0.2468
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0898 0.239 0.8209
Leishmania major DNA polymerase eta, putative 0.0032 0.0046 0.0116
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0055 0.0107 0.0105
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Leishmania major cathepsin L-like protease 0.082 0.2179 0.748
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0037 0.0058 0.0104
Brugia malayi Cathepsin L-like precursor 0.082 0.2179 0.4216
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Entamoeba histolytica hypothetical protein, conserved 0.0126 0.03 0.1329
Toxoplasma gondii PAN domain-containing protein 0.003 0.0041 0.0041
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0029 0.0051
Toxoplasma gondii prefoldin subunit 6, putative 0.0062 0.0127 0.0443
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0041 0.0075
Trypanosoma brucei kinesin, putative 0.048 0.1259 0.4306
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0854 0.2271 0.7797
Loa Loa (eye worm) hypothetical protein 0.0123 0.0292 0.0561
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Brugia malayi ImpB/MucB/SamB family protein 0.0046 0.0083 0.0156
Trichomonas vaginalis calpain, putative 0.0342 0.0885 0.4061
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0041 0.0075
Schistosoma mansoni cathepsin s 0.0253 0.0645 0.0643
Loa Loa (eye worm) trypsin family protein 0.0055 0.0107 0.0203
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.0054 0.0247
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0534 0.1406 0.2706
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.0529 0.1003
Leishmania major cathepsin L-like protease 0.082 0.2179 0.748
Trichomonas vaginalis calmodulin, putative 0.0027 0.0032 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Onchocerca volvulus 0.003 0.0041 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Trichomonas vaginalis kakapo, putative 0.0027 0.0032 0.0146
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0107 0.0105
Plasmodium vivax thioredoxin reductase, putative 0.0101 0.0233 0.0936
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0292 0.1338
Plasmodium vivax aspartyl protease, putative 0.0062 0.0127 0.0443
Giardia lamblia Cathepsin B precursor 0.0729 0.1933 1
Trypanosoma cruzi cruzipain precursor, putative 0.0253 0.0645 0.1228
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0267 0.0682 0.2312
Schistosoma mansoni amine GPCR 0.0026 0.003 0.0028
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0151 0.0693
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1986 0.5339 0.9984
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0009 0.0039
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0195 0.0486 0.0484
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0469 0.0467
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0026 0.003 0.0028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0144
Onchocerca volvulus 0.082 0.2179 0.7834
Plasmodium falciparum serine repeat antigen 5 0.0195 0.0486 0.2194
Leishmania major hypothetical protein, conserved 0.0126 0.03 0.0994
Echinococcus multilocularis calumenin 0.0126 0.03 0.0557
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Echinococcus multilocularis cathepsin l cysteine peptidase 0.082 0.2179 0.4072
Plasmodium vivax plasmepsin V, putative 0.0062 0.0127 0.0443
Loa Loa (eye worm) calpain family protein 1 0.1863 0.5006 0.9691
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0054 0.0081
Leishmania major cathepsin L-like protease 0.082 0.2179 0.748
Onchocerca volvulus 0.0073 0.0156 0.0531
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0573 0.151 0.2907
Plasmodium vivax aspartyl protease, putative 0.0062 0.0127 0.0443
Onchocerca volvulus Cathepsin L homolog 0.082 0.2179 0.7834
Loa Loa (eye worm) RecQ helicase 0.0022 0.0018 0.003
Schistosoma mansoni amine GPCR 0.0026 0.003 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0469 0.0467
Treponema pallidum NADH oxidase 0.0035 0.0054 0.5
Leishmania major small myristoylated protein-1 0.0363 0.0943 0.3213
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0699 0.1852 0.3571
Trypanosoma cruzi kinesin, putative 0.048 0.1259 0.242
Brugia malayi Trypsin-like protease protein 5 0.0055 0.0107 0.0203
Echinococcus granulosus EF hand domain containing family member A2 0.0123 0.0292 0.0542
Schistosoma mansoni myosin regulatory light chain 0.0027 0.0032 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Echinococcus multilocularis serotonin receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) calpain D 0.0342 0.0885 0.171
Schistosoma mansoni hypothetical protein 0.0026 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0123 0.0292 0.1338
Brugia malayi Cathepsin L-like precursor 0.0566 0.1493 0.2887
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.003 0.0053
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0123 0.0292 0.0543
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0049
Toxoplasma gondii microneme protein MIC4 0.003 0.0041 0.0041
Schistosoma mansoni myosin xvIII 0.0026 0.003 0.0028
Plasmodium falciparum calpain 0.0342 0.0885 0.4033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Schistosoma mansoni centrin 0.0123 0.0292 0.029
Plasmodium vivax vivapain-2 0.082 0.2179 0.9968
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0257 0.0656 1
Schistosoma mansoni cathepsin F (C01 family) 0.082 0.2179 0.2177
Plasmodium falciparum serine repeat antigen 4 0.0195 0.0486 0.2194
Echinococcus granulosus dna polymerase kappa 0.002 0.0012 0.0019
Onchocerca volvulus 0.0026 0.003 0.0073
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Trypanosoma brucei calpain-like protein, putative 0.0822 0.2186 0.7503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0566 0.1493 0.6851
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.0054 0.0102
Leishmania major cathepsin L-like protease 0.1012 0.2699 0.9274
Trichomonas vaginalis conserved hypothetical protein 0.0195 0.0486 0.2232
Echinococcus granulosus G protein coupled receptor 139 0.0026 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Plasmodium falciparum cysteine proteinase falcipain 1 0.0448 0.1172 0.5359
Onchocerca volvulus 0.0065 0.0136 0.0456
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0049
Plasmodium falciparum cysteine proteinase falcipain 2a 0.082 0.2179 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0109
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0012 0.0019
Schistosoma mansoni reticulocalbin 0.0126 0.03 0.0298
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Echinococcus granulosus Smad4 0.0017 0.0004 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0822 0.2186 0.4218
Onchocerca volvulus Peroxidase homolog 0.0065 0.0136 0.0457
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Schistosoma mansoni memapsin-2 (A01 family) 0.0464 0.1215 0.1213
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.003 0.0028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0898 0.239 0.4615
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Echinococcus granulosus neuropeptide receptor 0.0026 0.003 0.0052
Brugia malayi MH2 domain containing protein 0.0245 0.0623 0.1202
Plasmodium falciparum plasmepsin X 0.0062 0.0127 0.0539
Trichomonas vaginalis conserved hypothetical protein 0.0342 0.0885 0.4061
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0195 0.0486 0.0938
Echinococcus multilocularis cathepsin L 0.0195 0.0486 0.0906
Leishmania major cysteine peptidase A (CPA) 0.082 0.2179 0.748
Schistosoma mansoni calpain (C02 family) 0.0822 0.2186 0.2184
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0058 0.0105
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.0486 0.2232
Entamoeba histolytica cysteine protease, putative 0.0195 0.0486 0.2189
Onchocerca volvulus 0.0026 0.003 0.0073
Brugia malayi Probable ATP-dependent helicase DHX35 0.0031 0.0044 0.008
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0124 0.0237
Onchocerca volvulus 0.0026 0.003 0.0073
Trypanosoma cruzi cysteine peptidase, putative 0.082 0.2179 0.4205
Onchocerca volvulus 0.0026 0.003 0.0073
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.003 0.0052
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Trypanosoma brucei Calpain-like protein 1.1 0.0898 0.239 0.8209
Brugia malayi beta-lactamase 0.0037 0.0058 0.0109
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.0469 0.0873
Brugia malayi neuropeptide F receptor 0.0026 0.003 0.0053
Leishmania major hypothetical protein, conserved 0.0341 0.0883 0.3007
Trichomonas vaginalis calmodulin, putative 0.0123 0.0292 0.1338
Plasmodium falciparum thioredoxin reductase 0.0101 0.0233 0.1028
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.0054 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Toxoplasma gondii aspartyl protease ASP3 0.0062 0.0127 0.0445
Echinococcus granulosus calcyphosin protein 0.0027 0.0032 0.0055
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0123 0.0292 0.129
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0058 0.0056
Echinococcus granulosus serotonin receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0058 0.0116 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Leishmania major calmodulin, putative 0.0123 0.0292 0.0965
Toxoplasma gondii hypothetical protein 0.003 0.0041 0.0041
Trypanosoma brucei calmodulin, putative 0.0123 0.0292 0.0965
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0123 0.0292 0.1206
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0009 0.0039
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0448 0.1172 0.1171
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1089 0.2909 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1922 0.5166 0.5165
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0098
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Schistosoma mansoni neuropeptide receptor 0.0026 0.003 0.0028
Echinococcus multilocularis sex peptide receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0195 0.0486 0.0938
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0148 0.036 0.0693
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0195 0.0486 0.2189
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.003 0.0052
Schistosoma mansoni neuropeptide receptor 0.0026 0.003 0.0028
Brugia malayi GnHR receptor homolog 0.0026 0.003 0.0053
Trichomonas vaginalis calcium binding protein, putative 0.0123 0.0292 0.1338
Schistosoma mansoni ef hand domain family member A2 0.0123 0.0292 0.029
Trypanosoma brucei protein I/6 0.0123 0.0292 0.0965
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.0054 0.0097
Leishmania major prefoldin subunit, putative 0.0062 0.0127 0.0397
Trichomonas vaginalis calmodulin, putative 0.0123 0.0292 0.1338
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0037 0.0058 0.0158
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0061 0.0125 0.0238
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0054 0.0081
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0098 0.0404
Brugia malayi cathepsin L precursor 0.0195 0.0486 0.0938
Leishmania major hypothetical protein, conserved 0.0211 0.0529 0.1785
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0195 0.0486 0.211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0003
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Echinococcus multilocularis calcium uptake protein 1 0.0126 0.03 0.0557
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0046 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.0054 0.0247
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.0469 0.0873
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Echinococcus multilocularis prefoldin subunit 6 0.0062 0.0127 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0448 0.1172 0.5381
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0681 0.1803 0.6183
Entamoeba histolytica calmodulin, putative 0.0123 0.0292 0.129
Leishmania major hypothetical protein, conserved 0.0211 0.0529 0.1785
Echinococcus multilocularis EF hand domain containing family member A2 0.0126 0.03 0.0557
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0211 0.0529 0.1785
Brugia malayi Heterochromatin protein 1 0.0071 0.0151 0.0288
Onchocerca volvulus 0.003 0.0041 0.0113
Schistosoma mansoni biogenic amine receptor 0.0026 0.003 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0122
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Toxoplasma gondii cathepsin CPL 0.082 0.2179 1
Trypanosoma brucei small myristoylated protein 1-1 0.0363 0.0943 0.3213
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Schistosoma mansoni peroxidasin 0.0065 0.0136 0.0134
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0122
Schistosoma mansoni hypothetical protein 0.0055 0.0107 0.0105
Giardia lamblia Cathepsin L precursor 0.0195 0.0486 0.2468
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Brugia malayi Neuronal calcium sensor family protein 1 0.0027 0.0032 0.0057
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0026 0.003 0.0053
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0666 0.1764 0.6046
Trypanosoma cruzi calmodulin, putative 0.0123 0.0292 0.0543
Echinococcus granulosus cathepsin L 0.0195 0.0486 0.0906
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0448 0.1172 0.1171
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0609 0.1608 0.551
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0719
Giardia lamblia Cathepsin L precursor 0.0195 0.0486 0.2468
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.0054 0.0103
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0062 0.0127 0.0242
Entamoeba histolytica calmodulin, putative 0.0027 0.0032 0.0091
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0124 0.0229
Echinococcus granulosus chromobox protein 1 0.0071 0.0151 0.0278
Entamoeba histolytica calcium binding family protein 0.0123 0.0292 0.129
Toxoplasma gondii aspartyl protease 0.0062 0.0127 0.0445
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0136 0.0259
Trypanosoma cruzi cysteine peptidase, putative 0.1012 0.2699 0.5213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0308 0.0792 0.2694
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0195 0.0486 0.211
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0448 0.1172 0.4006
Echinococcus multilocularis cathepsin L 0.0448 0.1172 0.219
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0046 0.0085
Schistosoma mansoni cpg binding protein 0.0032 0.0045 0.0043
Onchocerca volvulus Cathepsin F homolog 0.082 0.2179 0.7834
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.0054 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Leishmania major protein kinase, putative 0.0123 0.0292 0.0965
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0448 0.1172 0.4006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0009 0.0039
Toxoplasma gondii subtilisin SUB12 0.003 0.0041 0.0041
Entamoeba histolytica cysteine protease, putative 0.0195 0.0486 0.2189
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0032 0.0038
Brugia malayi programmed cell death protein 6 0.0123 0.0292 0.0561
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0195 0.0486 0.2232
Onchocerca volvulus 0.0065 0.0136 0.0457
Brugia malayi Serotonin receptor 0.0026 0.003 0.0053
Onchocerca volvulus 0.0026 0.003 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Plasmodium falciparum plasmepsin IV 0.0209 0.0525 0.2374
Trichomonas vaginalis calcineurin B subunit, putative 0.0126 0.03 0.1377
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1089 0.2909 0.5621
Echinococcus granulosus chromobox protein 1 0.0071 0.0151 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0794 0.2108 0.7235
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0054 0.0144
Echinococcus granulosus cathepsin l1 0.0566 0.1493 0.2789
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0125 0.0123
Schistosoma mansoni opsin-like receptor 0.0026 0.003 0.0028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0898 0.239 0.8209
Trypanosoma brucei calpain, putative 0.0342 0.0885 0.3013
Entamoeba histolytica calpain large subunit domain III containing protein 0.048 0.1259 0.5757
Schistosoma mansoni hypothetical protein 0.0129 0.0307 0.0305
Echinococcus multilocularis calcyphosin protein 0.0027 0.0032 0.0055
Schistosoma mansoni calpain-7 (C02 family) 0.0822 0.2186 0.2184
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0211 0.0529 0.1785
Onchocerca volvulus 0.003 0.0041 0.0113
Echinococcus granulosus bloom syndrome protein 0.0022 0.0018 0.0029
Trichomonas vaginalis calcineurin B subunit, putative 0.0123 0.0292 0.1338
Giardia lamblia Calmodulin 0.0027 0.0032 0.0103
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.0054 0.0097
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Onchocerca volvulus 0.0055 0.0107 0.0352
Mycobacterium ulcerans hydrolase 0.0027 0.0031 0.2046
Plasmodium falciparum serine repeat antigen 3 0.0195 0.0486 0.2194
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0211 0.0529 0.1785
Trypanosoma cruzi hypothetical protein, conserved 0.0341 0.0883 0.169
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0195 0.0486 0.0484
Brugia malayi larval opioid receptor 0.0026 0.003 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Echinococcus multilocularis cathepsin b 0.1922 0.5166 0.966
Brugia malayi fibroinase precursor 0.0195 0.0486 0.0938
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.003 0.0052
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0609 0.1608 0.551
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.003 0.0052
Schistosoma mansoni biogenic amine receptor 0.0026 0.003 0.0028
Brugia malayi G-protein coupled receptor 0.0026 0.003 0.0053
Leishmania major hypothetical protein, conserved 0.0065 0.0136 0.0426
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0012 0.0055
Trichomonas vaginalis calmodulin, putative 0.0126 0.03 0.1377
Echinococcus granulosus calpain A 0.1989 0.5347 1
Trypanosoma cruzi prefoldin subunit, putative 0.0062 0.0127 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.0486 0.2232
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0553 0.1456 0.4983
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0123 0.0292 0.0543
Onchocerca volvulus 0.0566 0.1493 0.5356
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0553 0.1456 0.2801
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1245
Toxoplasma gondii preprocathepsin c precursor, putative 0.0195 0.0486 0.2117
Trichomonas vaginalis centrin, putative 0.0123 0.0292 0.1338
Echinococcus multilocularis enteropeptidase 0.0055 0.0107 0.0196
Schistosoma mansoni neuropeptide receptor 0.0026 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.0054 0.4406
Trichomonas vaginalis calmodulin-2, putative 0.0123 0.0292 0.1338
Echinococcus granulosus laminin 0.0028 0.0033 0.0059
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0195 0.0486 0.2468
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Onchocerca volvulus 0.0026 0.003 0.0073
Schistosoma mansoni cathepsin S (C01 family) 0.0195 0.0486 0.0484
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0055 0.0107 0.0203
Entamoeba histolytica cysteine proteinase 1, putative 0.0448 0.1172 0.5356
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0026 0.003 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.003 0.0052
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.0054 0.4406
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0195 0.0486 0.0484
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0203
Loa Loa (eye worm) myosin regulatory light chain 1 0.0027 0.0032 0.0057
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0122
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0096 0.0182
Schistosoma mansoni Mername-AA248 (C02 family) 0.0822 0.2186 0.2184
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0124 0.0122
Plasmodium falciparum plasmepsin V 0.0062 0.0127 0.0539
Trypanosoma brucei hypothetical protein 0.0609 0.1608 0.551
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0308 0.0792 0.1514
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0342 0.0885 0.3013
Onchocerca volvulus 0.0483 0.1267 0.4542
Plasmodium vivax hypothetical protein, conserved 0.0126 0.03 0.1245
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0098 0.0297
Echinococcus granulosus calmodulin 0.0123 0.0292 0.0542
Echinococcus multilocularis neuropeptide s receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0041 0.0075
Echinococcus multilocularis allatostatin A receptor 0.0026 0.003 0.0052
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Toxoplasma gondii microneme protein MIC17C 0.003 0.0041 0.0041
Brugia malayi calpain 5 0.0342 0.0885 0.171
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0075 0.0236
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0268
Echinococcus granulosus dro:myosuppressin receptor 0.0026 0.003 0.0052
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0009 0.0039
Plasmodium falciparum serine repeat antigen 7 0.0195 0.0486 0.2194
Loa Loa (eye worm) EF hand family protein 0.0123 0.0292 0.0561
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0109
Loa Loa (eye worm) hypothetical protein 0.1863 0.5006 0.9691
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0342 0.0885 0.3013
Trypanosoma cruzi kinesin, putative 0.048 0.1259 0.242
Schistosoma mansoni adenoreceptor 0.0026 0.003 0.0028
Echinococcus multilocularis neuropeptide receptor 0.0026 0.003 0.0052
Trichomonas vaginalis calpain, putative 0.0342 0.0885 0.4061
Brugia malayi Calcium binding EGF domain containing protein 0.0019 0.0009 0.0014
Trypanosoma cruzi cruzipain precursor, putative 0.1012 0.2699 0.5213
Trypanosoma cruzi small myristoylated protein 1-2 0.0363 0.0943 0.1806
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0195 0.0486 0.211
Trypanosoma cruzi prefoldin subunit, putative 0.0062 0.0127 0.0223
Schistosoma mansoni amine GPCR 0.0026 0.003 0.0028
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0151 0.0288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Loa Loa (eye worm) hypothetical protein 0.1922 0.5166 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0081
Entamoeba histolytica calmodulin, putative 0.0123 0.0292 0.129
Echinococcus granulosus g protein coupled receptor 0.0026 0.003 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0032 0.0146
Echinococcus multilocularis cpg binding protein 0.0032 0.0045 0.008
Mycobacterium tuberculosis Probable oxidoreductase 0.0257 0.0656 1
Loa Loa (eye worm) cysteine protease 0.082 0.2179 0.4216
Echinococcus multilocularis Smad4 0.0017 0.0004 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.0486 0.2232
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0553 0.1456 0.2801
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0729 0.1933 0.1932
Echinococcus granulosus allatostatin A receptor 0.0026 0.003 0.0052
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0026 0.003 0.0052
Schistosoma mansoni hypothetical protein 0.0123 0.0292 0.029
Schistosoma mansoni calpain C (C02 family) 0.0822 0.2186 0.2184
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.1108 0.2142
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0055 0.0107 0.0196
Brugia malayi Cytochrome P450 family protein 0.0032 0.0046 0.0085
Echinococcus granulosus lamin dm0 0.0055 0.0107 0.0197
Trypanosoma cruzi cysteine proteinase, putative 0.0448 0.1172 0.2252
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0253 0.0645 0.1245
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0075 0.0342
Echinococcus multilocularis cathepsin b 0.1922 0.5166 0.966
Leishmania major hypothetical protein, conserved 0.0211 0.0529 0.1785
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0204
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.1456 0.2801
Toxoplasma gondii ABC1 family protein 0.0037 0.0058 0.0124
Entamoeba histolytica calpain family cysteine protease, putative 0.0342 0.0885 0.4028
Leishmania major cytochrome p450-like protein 0.0032 0.0046 0.0117
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0058 0.009
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0004 0.0003
Brugia malayi cathepsin L-like precursor 0.0566 0.1493 0.2887
Brugia malayi Trypsin family protein 0.0055 0.0107 0.0203
Brugia malayi putative neuropeptide receptor 0.0026 0.003 0.0053
Echinococcus multilocularis muscleblind protein 0.0148 0.036 0.0669
Echinococcus multilocularis transmembrane protease serine 3 0.0055 0.0107 0.0196
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0041 0.0075
Echinococcus granulosus 7TM GPCR rhodopsin 0.0026 0.003 0.0052
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0026 0.003 0.0052
Echinococcus granulosus dna polymerase eta 0.0046 0.0083 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0035 0.016
Brugia malayi Blistered cuticle protein 3 0.0065 0.0136 0.0259
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0057
Trypanosoma brucei calpain-like protein, putative 0.0822 0.2186 0.7503
Echinococcus granulosus cysteine protease 0.0448 0.1172 0.219
Loa Loa (eye worm) blistered cuticle protein 3 0.0065 0.0136 0.0259
Schistosoma mansoni amine GPCR 0.0026 0.003 0.0028
Onchocerca volvulus Matrilysin homolog 0.0022 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0268
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0062 0.0127 0.0242
Schistosoma mansoni calpain-7 (C02 family) 0.0822 0.2186 0.2184
Onchocerca volvulus 0.0026 0.003 0.0073
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.1456 0.2801
Brugia malayi Peroxidasin 0.0065 0.0136 0.0259
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0004 0.0003
Trichomonas vaginalis centrin, putative 0.0027 0.0032 0.0146
Echinococcus granulosus EF HAND 1 calcium binding site 0.0123 0.0292 0.0542
Echinococcus granulosus calpain 5 0.0822 0.2186 0.4085
Brugia malayi Papain family cysteine protease containing protein 0.0448 0.1172 0.2267
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0203
Plasmodium falciparum prefoldin subunit 6, putative 0.0062 0.0127 0.0537
Brugia malayi hypothetical protein 0.0051 0.0098 0.0186
Leishmania major hypothetical protein, conserved 0.0562 0.148 0.5067
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0719
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0046 0.0117
Trichomonas vaginalis caltractin, putative 0.0027 0.0032 0.0146
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0083 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0195 0.0486 0.2232
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1245
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0822 0.2186 0.4218
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0267 0.0682 0.2312
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0203
Plasmodium falciparum glutathione reductase 0.0035 0.0054 0.02
Schistosoma mansoni thyroid hormone receptor 0.0139 0.0335 0.0333
Trichomonas vaginalis calpain, putative 0.0342 0.0885 0.4061
Leishmania major calmodulin, putative 0.0123 0.0292 0.0965
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0136 0.0259
Plasmodium falciparum plasmepsin II 0.0209 0.0525 0.2374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.0486 0.2232
Echinococcus multilocularis calpain family protein 1, d 0.1383 0.3705 0.6928
Loa Loa (eye worm) hypothetical protein 0.0324 0.0837 0.1618
Echinococcus granulosus prefoldin subunit 6 0.0062 0.0127 0.0234
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0026 0.003 0.0053
Leishmania major calcineurin B subunit, putative 0.0123 0.0292 0.0965
Brugia malayi aspartic protease BmAsp-2, identical 0.0062 0.0127 0.0242
Toxoplasma gondii cathepsin B 0.0729 0.1933 0.8857
Schistosoma mansoni hypothetical protein 0.0346 0.0896 0.0894
Echinococcus granulosus calpain 7 C02 family 0.0822 0.2186 0.4085
Plasmodium vivax calpain, putative 0.0822 0.2186 1
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0098 0.0308
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0123 0.0292 0.0542
Brugia malayi cathepsin F-like cysteine proteinase 0.0253 0.0645 0.1245
Brugia malayi EF hand family protein 0.0126 0.03 0.0577
Trypanosoma cruzi centrin-3 0.015 0.0365 0.0685
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Trichomonas vaginalis calmodulin, putative 0.015 0.0365 0.1674
Toxoplasma gondii calcium binding egf domain-containing protein 0.0028 0.0033 0.0008
Brugia malayi Calcium binding EGF domain containing protein 0.0028 0.0033 0.0061
Mycobacterium ulcerans hypothetical protein 0.0055 0.0107 1
Schistosoma mansoni cathepsin B (C01 family) 0.0195 0.0486 0.0484
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Onchocerca volvulus 0.0062 0.0127 0.0426
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.0596 0.907
Leishmania major hypothetical protein, conserved 0.0211 0.0529 0.1785
Plasmodium falciparum plasmepsin VIII, putative 0.0062 0.0127 0.0539
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0195 0.0486 0.0484
Echinococcus multilocularis thyroid hormone receptor alpha 0.0139 0.0335 0.0623
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0004 0.0003
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Schistosoma mansoni biogenic amine receptor 0.0026 0.003 0.0028
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Brugia malayi Thioredoxin reductase 0.0101 0.0233 0.0448
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0126 0.03 0.0298
Echinococcus multilocularis neuropeptide receptor A26 0.0026 0.003 0.0052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0081
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0125 0.0123
Onchocerca volvulus 0.0026 0.003 0.0073
Onchocerca volvulus 0.0055 0.0107 0.0352
Echinococcus granulosus hypothetical protein 0.0026 0.003 0.0052
Onchocerca volvulus 0.003 0.0041 0.0113
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Trypanosoma cruzi cysteine peptidase, putative 0.0448 0.1172 0.2252
Schistosoma mansoni hypothetical protein 0.0055 0.0107 0.0105
Echinococcus granulosus thioredoxin glutathione reductase 0.0101 0.0233 0.0433
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1986 0.5339 0.5338
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1026 0.2738 0.5119
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0026 0.003 0.0053
Echinococcus granulosus neuropeptide receptor A26 0.0026 0.003 0.0052
Brugia malayi putative neuropeptide receptor NPR1 0.0026 0.003 0.0053
Schistosoma mansoni cpg binding protein 0.0032 0.0045 0.0043
Echinococcus multilocularis fibrillin 1 0.0028 0.0033 0.0059
Leishmania major trypanothione reductase 0.0101 0.0233 0.0764
Brugia malayi RE15519p 0.0026 0.003 0.0053
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0342 0.0885 0.4061
Trypanosoma cruzi I/6 autoantigen, putative 0.0123 0.0292 0.0543
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Brugia malayi Calmodulin-like protein 0.0123 0.0292 0.0561
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0203
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0136 0.0457
Echinococcus multilocularis calpain 0.0822 0.2186 0.4085
Plasmodium vivax vivapain-3 0.0448 0.1172 0.5296
Brugia malayi Trypsin family protein 0.0055 0.0107 0.0203
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) calpain 0.0822 0.2186 0.4229
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0026 0.003 0.0052
Echinococcus multilocularis G-protein coupled receptor, putative 0.0026 0.003 0.0052
Trichomonas vaginalis esterase, putative 0.0037 0.0058 0.0268
Plasmodium falciparum serine repeat antigen 8 0.0195 0.0486 0.2194
Entamoeba histolytica cysteine proteinase, putative 0.082 0.2179 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0004 0.0003
Echinococcus granulosus 7tm_1 domain containing protein 0.0026 0.003 0.0052
Echinococcus granulosus peptide allatostatin:somatostatin 0.0026 0.003 0.0052
Plasmodium vivax centrin-1, putative 0.0123 0.0292 0.1206
Schistosoma mansoni hypothetical protein 0.0053 0.0102 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0195 0.0486 0.2232
Giardia lamblia Cathepsin B precursor 0.0729 0.1933 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0195 0.0486 0.0484
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0136 0.0259
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0018 0.003
Plasmodium falciparum serine repeat antigen 6 0.0195 0.0486 0.2194
Brugia malayi G protein-coupled receptor F59B2.13 0.0026 0.003 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.003 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0124 0.0237
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0195 0.0486 0.0484
Onchocerca volvulus 0.0055 0.0107 0.0354
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0123 0.0292 0.1338
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0026 0.003 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0081
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.0054 0.4406
Loa Loa (eye worm) cathepsin B 0.0729 0.1933 0.374
Leishmania major hypothetical protein, conserved 0.0037 0.0058 0.016
Brugia malayi beta-lactamase family protein 0.0037 0.0058 0.0109
Schistosoma mansoni cathepsin C 0.0195 0.0486 0.0484
Loa Loa (eye worm) hypothetical protein 0.0209 0.0525 0.1013
Brugia malayi Matrixin family protein 0.0022 0.0018 0.0032
Schistosoma mansoni Smad4 0.0017 0.0004 0.0002
Entamoeba histolytica cysteine protease, putative 0.082 0.2179 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0066 0.0305
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Giardia lamblia Cathepsin B precursor 0.0195 0.0486 0.2468
Echinococcus multilocularis calpain A 0.1989 0.5347 1
Entamoeba histolytica cysteine protease, putative 0.0448 0.1172 0.5356
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Loa Loa (eye worm) hypothetical protein 0.004 0.0066 0.0125
Onchocerca volvulus 0.003 0.004 0.0112
Echinococcus granulosus Myosin regulatory light chain 0.0027 0.0032 0.0055
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0028 0.0033 0.0061
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0003
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.008 0.0176 0.0325
Echinococcus multilocularis somatostatin receptor 0.0026 0.003 0.0052
Plasmodium vivax SET domain protein, putative 0.0061 0.0125 0.0433
Trypanosoma cruzi conserved protein 0.0562 0.148 0.2849
Brugia malayi Dopamine receptor 0.0026 0.003 0.0053
Schistosoma mansoni hypothetical protein 0.0026 0.003 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Onchocerca volvulus 0.0026 0.003 0.0073
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0758 0.2012 0.3882
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1922 0.5166 0.5165
Brugia malayi hypothetical protein 0.0065 0.0136 0.0259
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0195 0.0486 0.211
Loa Loa (eye worm) hypothetical protein 0.0054 0.0105 0.0198
Brugia malayi Eukaryotic aspartyl protease family protein 0.0062 0.0127 0.0242
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0209 0.0525 0.241
Entamoeba histolytica cysteine protease, putative 0.0195 0.0486 0.2189
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0002
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0674 0.1784 0.1783
Echinococcus granulosus cathepsin l1 0.082 0.2179 0.4072
Trypanosoma brucei Calpain-like protein 2 0.0681 0.1803 0.6183
Trypanosoma cruzi cysteine peptidase, putative 0.0253 0.0645 0.1228
Brugia malayi cathepsin B-like cysteine proteinase 0.1922 0.5166 1
Echinococcus granulosus Calcium binding protein 0.0027 0.0032 0.0055
Echinococcus multilocularis sodium channel protein 0.0037 0.0058 0.0104
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0211 0.0529 0.1003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1015 0.2707 0.523
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0058 0.0719
Plasmodium falciparum serine repeat antigen 9 0.0195 0.0486 0.2194
Brugia malayi CXXC zinc finger family protein 0.003 0.004 0.0074
Brugia malayi calpain family protein 1 0.1863 0.5006 0.9691
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0136 0.0259
Leishmania major small myristoylated protein 4, putative 0.0573 0.151 0.5171
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0448 0.1172 0.1171
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Trichomonas vaginalis centrin, putative 0.0027 0.0032 0.0146
Giardia lamblia Cathepsin B precursor 0.0195 0.0486 0.2468
Echinococcus multilocularis programmed cell death protein 0.015 0.0365 0.0679
Onchocerca volvulus Matrix metalloproteinase homolog 0.0049 0.0091 0.0296
Echinococcus multilocularis Mastin 0.0055 0.0107 0.0196
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0195 0.0486 0.0938
Trypanosoma cruzi unspecified product 0.0363 0.0943 0.1806
Giardia lamblia Cathepsin B precursor 0.0195 0.0486 0.2468
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1089 0.2909 0.5621
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0188 0.0469 0.0904
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.005 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0058 0.009
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0026 0.003 0.0073
Giardia lamblia Hypothetical protein 0.0195 0.0486 0.2468
Entamoeba histolytica cysteine proteinase, putative 0.0448 0.1172 0.5356
Brugia malayi G protein-coupled receptor 0.0026 0.003 0.0053
Trypanosoma cruzi major cysteine proteinase, putative 0.0195 0.0486 0.092
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0065 0.0136 0.0482
Plasmodium vivax vivapain-2 0.082 0.2179 0.9968
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0195 0.0486 0.2468
Mycobacterium ulcerans lipase LipD 0.0037 0.0058 0.4878
Trichomonas vaginalis calmodulin, putative 0.0123 0.0292 0.1338
Echinococcus granulosus neuropeptide receptor 0.0026 0.003 0.0052
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0058 0.0719
Echinococcus multilocularis g protein coupled receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) AStacin protease 0.0028 0.0035 0.0064
Giardia lamblia Cysteine protease 0.0195 0.0486 0.2468
Trypanosoma cruzi calmodulin, putative 0.0123 0.0292 0.0543
Brugia malayi Dopamine receptor protein 1 0.0026 0.003 0.0053
Brugia malayi EF hand family protein 0.0123 0.0292 0.0561
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0026 0.003 0.0028
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0101 0.0233 0.3441
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0267 0.0682 0.2312
Trichomonas vaginalis calmodulin, putative 0.0123 0.0292 0.1338
Brugia malayi PAN domain containing protein 0.003 0.0041 0.0075
Toxoplasma gondii thioredoxin reductase 0.0101 0.0233 0.0939
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Brugia malayi hypothetical protein 0.0033 0.0049 0.009
Onchocerca volvulus 0.003 0.0041 0.0113
Giardia lamblia Cysteine protease 0.0195 0.0486 0.2468
Onchocerca volvulus 0.003 0.0041 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0066 0.0305
Brugia malayi Cytochrome P450 family protein 0.0032 0.0046 0.0085
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.0054 0.02
Onchocerca volvulus 0.0065 0.0136 0.0457
Echinococcus granulosus programmed cell death protein 0.015 0.0365 0.0679
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Brugia malayi KE2 family protein 0.0062 0.0127 0.0242
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0021 0.0036
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0009 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.0486 0.2232
Trichomonas vaginalis calcium binding protein, putative 0.015 0.0365 0.1674
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0026 0.003 0.0053
Onchocerca volvulus Cathepsin L homolog 0.0195 0.0486 0.1722
Echinococcus multilocularis Tolloid protein 1 0.0058 0.0116 0.0214
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.082 0.2179 0.4216
Toxoplasma gondii cathepsin CPC1 0.0195 0.0486 0.2117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Echinococcus multilocularis laminin 0.0028 0.0033 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Onchocerca volvulus 0.0026 0.003 0.0073
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1012 0.2699 0.9274
Trypanosoma cruzi hypothetical protein, conserved 0.0341 0.0883 0.169
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0136 0.0457
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0209 0.0525 0.2298
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0566 0.1493 0.2887
Echinococcus multilocularis smad 0.0017 0.0004 0.0003
Plasmodium vivax unspecified product 0.0448 0.1172 0.5296
Onchocerca volvulus 0.0026 0.003 0.0073
Echinococcus multilocularis peroxidasin 0.0065 0.0136 0.025
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0062 0.0127 0.0445
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0123 0.0292 0.0542
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0666 0.1764 0.3399
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Echinococcus multilocularis musashi 0.0055 0.0107 0.0197
Schistosoma mansoni hypothetical protein 0.0031 0.0043 0.0041
Brugia malayi Cathepsin L-like cysteine proteinase 0.0566 0.1493 0.2887
Giardia lamblia Cathepsin L precursor 0.0195 0.0486 0.2468
Echinococcus multilocularis fmrfamide receptor 0.0026 0.003 0.0052
Onchocerca volvulus 0.0123 0.0292 0.1019
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0123 0.0292 0.0965
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0046 0.0065
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0203
Loa Loa (eye worm) TYRA-2 protein 0.0026 0.003 0.0053
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0046 0.0085
Giardia lamblia Cathepsin L-like protease 0.0195 0.0486 0.2468
Toxoplasma gondii centrin, putative 0.0123 0.0292 0.121
Echinococcus granulosus sex peptide receptor 0.0026 0.003 0.0052
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0124 0.0237
Loa Loa (eye worm) calmodulin-like protein 0.0123 0.0292 0.0561
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.003 0.0053
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0898 0.239 0.4615
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Onchocerca volvulus 0.0026 0.003 0.0073
Loa Loa (eye worm) melatonin receptor type 1A 0.0026 0.003 0.0053
Brugia malayi intermediate filament protein 0.0055 0.0107 0.0204
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0026 0.003 0.0028
Loa Loa (eye worm) Smad1 0.0017 0.0004 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Onchocerca volvulus 0.082 0.2179 0.7834
Trypanosoma cruzi calmodulin, putative 0.0123 0.0292 0.0543
Plasmodium vivax vivapain-1 0.0448 0.1172 0.5296
Echinococcus granulosus Tolloid protein 1 0.0058 0.0116 0.0214
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0003
Echinococcus granulosus cpg binding protein 0.0032 0.0045 0.008
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0342 0.0885 0.4061
Echinococcus multilocularis g protein coupled receptor 0.0026 0.003 0.0052
Schistosoma mansoni hypothetical protein 0.0342 0.0885 0.0883
Loa Loa (eye worm) hypothetical protein 0.0195 0.0486 0.0938
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Plasmodium falciparum serine repeat antigen 1 0.0195 0.0486 0.2194
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.003 0.0052
Brugia malayi Trypsin family protein 0.0055 0.0107 0.0203
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0125 0.023
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0026 0.003 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Toxoplasma gondii PAN domain-containing protein 0.003 0.0041 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.082 0.2179 1
Trichomonas vaginalis centrin, putative 0.0123 0.0292 0.1338
Mycobacterium ulcerans beta-lactamase 0.0037 0.0058 0.4878
Giardia lamblia Cathepsin B precursor 0.0195 0.0486 0.2468
Echinococcus multilocularis dro:myosuppressin receptor 0.0026 0.003 0.0052
Schistosoma mansoni hypothetical protein 0.0023 0.0021 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.003 0.0052
Schistosoma mansoni rab 0.0123 0.0292 0.029
Echinococcus granulosus cathepsin L cysteine proteinase 0.082 0.2179 0.4072
Echinococcus granulosus fmrfamide receptor 0.0026 0.003 0.0052
Brugia malayi cathepsin L-like cysteine proteinase 0.0195 0.0486 0.0938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Loa Loa (eye worm) hypothetical protein 0.1041 0.2779 0.5377
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Giardia lamblia Programmed cell death protein-like protein 0.0027 0.0032 0.0103
Toxoplasma gondii aspartyl protease ASP1 0.0209 0.0525 0.2298
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0107 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.003 0.0052
Trichomonas vaginalis calcium binding protein, putative 0.0123 0.0292 0.1338
Brugia malayi Papain family cysteine protease containing protein 0.0195 0.0486 0.0938
Brugia malayi Matrixin family protein 0.0022 0.0018 0.0032
Echinococcus granulosus Mastin 0.0055 0.0107 0.0196
Brugia malayi RNA binding protein 0.0061 0.0124 0.0237
Trypanosoma brucei calpain-like protein, putative 0.0822 0.2186 0.7503
Brugia malayi Papain family cysteine protease containing protein 0.0195 0.0486 0.0938
Loa Loa (eye worm) hypothetical protein 0.0062 0.0127 0.0242
Echinococcus granulosus g protein coupled receptor 0.0026 0.003 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.0054 0.0649
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.003 0.0052
Schistosoma mansoni calpain-2 (C02 family) 0.0342 0.0885 0.0883
Loa Loa (eye worm) TK/ROR protein kinase 0.0065 0.0136 0.0258
Onchocerca volvulus 0.0055 0.0107 0.0352
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.004 0.0074
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1986 0.5339 0.5338
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0058 0.0268
Loa Loa (eye worm) hypothetical protein 0.0566 0.1493 0.2887
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0009 0.0039
Echinococcus multilocularis hypothetical protein 0.0822 0.2186 0.4085
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0058 0.0116 0.0114
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.003 0.0053
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.0054 0.0102
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0107 0.0196
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0109
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0231 0.0586 0.8913
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1922 0.5166 1
Schistosoma mansoni thyroid hormone receptor 0.0139 0.0335 0.0333
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0035 0.0054 0.5
Echinococcus granulosus smad 0.0017 0.0004 0.0003
Trichomonas vaginalis centrin, putative 0.0027 0.0032 0.0146
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1922 0.5166 0.5165
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.003 0.0053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.0469 0.0873
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Echinococcus multilocularis fmrfamide receptor 0.0026 0.003 0.0052
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0342 0.0885 0.3974
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Brugia malayi Matrixin family protein 0.0022 0.0018 0.0032
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.003 0.0052
Echinococcus multilocularis geminin 0.0346 0.0896 0.1672
Plasmodium falciparum serine repeat antigen 2 0.0195 0.0486 0.2194
Brugia malayi calpain 7 0.0822 0.2186 0.4229
Plasmodium falciparum cysteine proteinase falcipain 3 0.082 0.2179 1
Schistosoma mansoni neuropeptide receptor 0.0026 0.003 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.0529 0.1003
Trypanosoma brucei conserved protein 0.022 0.0554 0.187
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0195 0.0486 0.0484
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0026 0.003 0.0052
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0058 0.0105
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0719
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0123 0.0292 0.0542
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0342 0.0885 0.4061
Onchocerca volvulus 0.0026 0.003 0.0073
Trypanosoma cruzi caltractin, putative 0.0123 0.0292 0.0543
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.003 0.0052
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0211 0.0529 0.1785
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0822 0.2186 0.4218
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0041 0.0041
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0055 0.0107 0.0196
Brugia malayi G-protein coupled receptor 0.0026 0.003 0.0053
Leishmania major calmodulin-like protein 0.0123 0.0292 0.0965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.003 0.0028
Trypanosoma brucei antigen, putative 0.0822 0.2186 0.7503
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0109
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0058 0.0109
Brugia malayi TAR-binding protein 0.0061 0.0124 0.0237
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0026 0.003 0.0052
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0699 0.1852 0.3571
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0009 0.0039
Leishmania major centrin, putative 0.0123 0.0292 0.0965
Echinococcus multilocularis cysteine protease 0.082 0.2179 0.4072
Loa Loa (eye worm) beta-lactamase 0.0037 0.0058 0.0109
Loa Loa (eye worm) myosin Light Chain family member 0.003 0.004 0.0074
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Schistosoma mansoni opsin-like receptor 0.0026 0.003 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.0529 0.1003
Echinococcus granulosus muscleblind protein 0.0148 0.036 0.0669
Echinococcus multilocularis neuropeptide FF receptor 2 0.0026 0.003 0.0052
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.003 0.0028
Toxoplasma gondii calcium binding egf domain-containing protein 0.0028 0.0033 0.0008
Brugia malayi Kringle domain containing protein 0.0065 0.0136 0.0258
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0046 0.0066
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.0054 0.0144
Trypanosoma brucei prefoldin subunit, putative 0.0062 0.0127 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0195 0.0486 0.2232
Loa Loa (eye worm) hypothetical protein 0.0195 0.0486 0.0938
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0117 0.0115
Onchocerca volvulus 0.0026 0.003 0.0073
Loa Loa (eye worm) aspartyl protease 6 0.0062 0.0127 0.0242
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Schistosoma mansoni calmodulin-related 0.0027 0.0032 0.003
Entamoeba histolytica cysteine proteinase, putative 0.0448 0.1172 0.5356
Brugia malayi Probable myosin regulatory light chain 0.003 0.004 0.0074
Trichomonas vaginalis calcium binding proteins, putative 0.0123 0.0292 0.1338
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0885 0.171
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0231 0.0586 0.8913
Trypanosoma cruzi I/6 autoantigen, putative 0.0123 0.0292 0.0543
Brugia malayi ORL1-like opioid receptor 0.0026 0.003 0.0053
Leishmania major programmed cell death 6 protein-like protein 0.0123 0.0292 0.0965
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0308 0.0792 0.1514
Onchocerca volvulus 0.1041 0.2779 1
Toxoplasma gondii PAN domain-containing protein 0.003 0.0041 0.0041
Trichomonas vaginalis hypothetical protein 0.0342 0.0885 0.4061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0898 0.239 0.8209
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0081
Echinococcus multilocularis Myosin regulatory light chain 0.0027 0.0032 0.0055
Onchocerca volvulus 0.0026 0.003 0.0073
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0012 0.0019
Brugia malayi hypothetical protein 0.0062 0.0127 0.0242
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0195 0.0486 0.211
Plasmodium falciparum thioredoxin reductase 0.0035 0.0054 0.02
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1863 0.5006 0.5005
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0066 0.0206
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0026 0.003 0.0052
Plasmodium falciparum cysteine proteinase falcipain 2b 0.082 0.2179 1
Schistosoma mansoni cathepsin F (C01 family) 0.0566 0.1493 0.1491
Schistosoma mansoni calmodulin 0.0123 0.0292 0.029
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0057
Giardia lamblia Encystation-specific protease 0.0195 0.0486 0.2468
Loa Loa (eye worm) hypothetical protein 0.0148 0.036 0.0693
Loa Loa (eye worm) hypothetical protein 0.0027 0.0032 0.0057
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0018 0.0081
Brugia malayi Papain family cysteine protease containing protein 0.0448 0.1172 0.2267
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0231 0.0586 0.8913
Loa Loa (eye worm) hypothetical protein 0.082 0.2179 0.4216
Echinococcus multilocularis g-protein coupled receptor 0.0026 0.003 0.0052
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0123 0.0292 0.0543
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0342 0.0885 0.4061
Brugia malayi Cathepsin L-like precursor 0.082 0.2179 0.4216
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Onchocerca volvulus 0.0055 0.0107 0.0352
Leishmania major calmodulin-like protein 0.0123 0.0292 0.0965
Schistosoma mansoni hypothetical protein 0.0346 0.0896 0.0894
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.003 0.0028
Echinococcus multilocularis Calcium binding protein 0.0027 0.0032 0.0055
Plasmodium vivax unspecified product 0.0253 0.0645 0.2846
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0098 0.0404
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0058 0.0268
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0203
Schistosoma mansoni cercarial elastase (S01 family) 0.0055 0.0107 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0081
Toxoplasma gondii calcium-dependent protein kinase 0.0126 0.03 0.1249
Giardia lamblia Cathepsin B precursor 0.0195 0.0486 0.2468
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.0469 0.0873
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0257 0.0656 1
Entamoeba histolytica protein kinase, putative 0.048 0.1259 0.5757
Mycobacterium tuberculosis Probable dehydrogenase 0.0231 0.0586 0.8913
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0898 0.239 0.4615
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Trypanosoma brucei calpain-like protein, putative 0.1089 0.2909 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0209 0.0525 0.0523
Echinococcus granulosus cathepsin b 0.1922 0.5166 0.966
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0014
Echinococcus granulosus tachykinin peptides receptor 99D 0.1467 0.3931 0.735
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.082 0.2179 1
Brugia malayi Cathepsin L-like precursor 0.082 0.2179 0.4216
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0699 0.1852 0.6352
Plasmodium vivax plasmepsin IV, putative 0.0209 0.0525 0.2291
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Trypanosoma brucei Calpain-like protein CALP1.3 0.0553 0.1456 0.4983
Leishmania major small myristoylated protein-2 0.0662 0.1752 0.6007
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0058 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.003 0.0052
Leishmania major cathepsin L-like protease 0.082 0.2179 0.748
Brugia malayi Tachykinin-like peptides receptor 99D 0.0026 0.003 0.0053
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0026 0.003 0.0052
Echinococcus granulosus g protein coupled receptor 0.0026 0.003 0.0052
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0117 0.0115
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0195 0.0486 0.0938
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0267 0.0682 0.13
Echinococcus granulosus lamin 0.0055 0.0107 0.0197
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0038 0.007
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.003 0.0052
Toxoplasma gondii PAN domain-containing protein 0.003 0.0041 0.0041
Brugia malayi Papain family cysteine protease containing protein 0.0195 0.0486 0.0938
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1089 0.2909 0.5621
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Trypanosoma brucei trypanothione reductase 0.0101 0.0233 0.0764
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0123 0.0292 0.0965
Schistosoma mansoni growth hormone secretagogue receptor 0.0026 0.003 0.0028
Onchocerca volvulus 0.003 0.0041 0.0113
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0018 0.0081
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Onchocerca volvulus 0.0065 0.0136 0.0457
Schistosoma mansoni lamin 0.0055 0.0107 0.0105
Echinococcus multilocularis serotonin receptor 0.0026 0.003 0.0052
Plasmodium vivax prefoldin subunit 6, putative 0.0062 0.0127 0.0442
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0098 0.0167
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0058 0.4878
Brugia malayi neuropeptide F receptor 0.0026 0.003 0.0053
Echinococcus multilocularis neurocalcin 0.0123 0.0292 0.0542
Onchocerca volvulus 0.082 0.2179 0.7834
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.003 0.0028
Trypanosoma brucei cysteine peptidase C (CPC) 0.0729 0.1933 0.6633
Trypanosoma brucei calmodulin, putative 0.0126 0.03 0.0994
Echinococcus granulosus orexin receptor type 2 0.0026 0.003 0.0052
Trypanosoma cruzi cysteine peptidase, putative 0.1012 0.2699 0.5213
Echinococcus multilocularis cathepsin L cysteine protease 0.082 0.2179 0.4072
Onchocerca volvulus 0.003 0.0041 0.0113
Loa Loa (eye worm) DEAH box polypeptide 35 0.0031 0.0044 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.082 0.2179 1
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.0018 0.0032
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.003 0.0028
Brugia malayi RasGEF domain containing protein 0.0027 0.0032 0.0057
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0098 0.0308
Loa Loa (eye worm) ctsf protein 0.082 0.2179 0.4216
Echinococcus multilocularis lamin 0.0055 0.0107 0.0197
Giardia lamblia Hypothetical protein 0.0195 0.0486 0.2468
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0026 0.003 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0195 0.0486 0.2232
Leishmania major hypothetical protein, conserved 0.0123 0.0292 0.0965
Echinococcus granulosus EF hand domain containing family member A2 0.0126 0.03 0.0557
Echinococcus granulosus programmed cell death protein 6 0.003 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Schistosoma mansoni peroxidasin 0.0065 0.0136 0.0134
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0004 0.0003
Echinococcus granulosus sodium channel protein 0.0037 0.0058 0.0104
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0026 0.003 0.0052
Onchocerca volvulus Neuropeptide F receptor homolog 0.0026 0.003 0.0073
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0054 0.0144
Trichomonas vaginalis calmodulin, putative 0.0123 0.0292 0.1338
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0107 0.0204
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0308 0.0792 0.1514
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0026 0.003 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0195 0.0486 0.2232
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0041 0.0075
Loa Loa (eye worm) hypothetical protein 0.0065 0.0136 0.0259
Toxoplasma gondii microneme protein MIC17A 0.003 0.0041 0.0041
Onchocerca volvulus 0.0055 0.0107 0.0352
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0195 0.0486 0.2194
Loa Loa (eye worm) RNA binding protein 0.0061 0.0124 0.0237
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1015 0.2707 0.523
Brugia malayi Cathepsin L-like precursor 0.0253 0.0645 0.1245
Echinococcus multilocularis g protein coupled receptor 0.0026 0.003 0.0052
Schistosoma mansoni hypothetical protein 0.0035 0.0053 0.0051
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0666 0.1764 0.3399
Plasmodium vivax aspartyl proteinase, putative 0.0062 0.0127 0.0443
Onchocerca volvulus 0.082 0.2179 0.7834
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0729 0.1933 0.8874
Loa Loa (eye worm) hypothetical protein 0.0055 0.0107 0.0203
Plasmodium vivax serine-repeat antigen (SERA) 0.0195 0.0486 0.211
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0055 0.0107 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.003 0.0052
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.0054 0.0052
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0058 0.0719
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0156 0.0154
Trichomonas vaginalis calcium binding protein, putative 0.0123 0.0292 0.1338
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0026 0.003 0.0028
Schistosoma mansoni smad 0.0017 0.0004 0.0002
Brugia malayi Protein kinase domain containing protein 0.0065 0.0136 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.082 0.2179 1
Brugia malayi sulfakinin receptor protein 0.0026 0.003 0.0053
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0046 0.3564
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0026 0.003 0.0028
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.003 0.0052
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0144
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0032
Toxoplasma gondii centrin 0.0123 0.0292 0.121
Trypanosoma brucei cysteine peptidase, putative 0.0553 0.1456 0.4983
Leishmania major META domain containing protein 0.0211 0.0529 0.1785
Trypanosoma cruzi cysteine peptidase, putative 0.1012 0.2699 0.5213
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0127 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.0883 0.4053
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.1456 0.2801
Brugia malayi hypothetical protein 0.0026 0.003 0.0053
Echinococcus multilocularis lamin dm0 0.0055 0.0107 0.0197
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0053
Schistosoma mansoni amine GPCR 0.0026 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0055
Echinococcus multilocularis chromobox protein 1 0.0071 0.0151 0.0278
Onchocerca volvulus 0.0037 0.0058 0.0177
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0553 0.1456 0.2801
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0209 0.0525 0.0979
Echinococcus granulosus calbindin 32 0.0126 0.03 0.0557
Giardia lamblia Cathepsin L-like protease 0.0195 0.0486 0.2468
Echinococcus granulosus peroxidasin 0.0065 0.0136 0.025
Leishmania major hypothetical protein, unknown function 0.0342 0.0885 0.3013
Onchocerca volvulus 0.0031 0.0043 0.0123
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.1521 0.408 0.7897
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0123 0.0292 0.029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0054 0.0081
Toxoplasma gondii kringle domain-containing protein 0.0065 0.0136 0.0483
Echinococcus multilocularis neuronal calcium sensor 0.0123 0.0292 0.0542
Toxoplasma gondii microneme protein, putative 0.003 0.0041 0.0041
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0188 0.0469 0.0904
Loa Loa (eye worm) transcription factor SMAD2 0.0245 0.0623 0.1202
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0136 0.0259

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 5.72 nM Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells ChEMBL. 24900216

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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