Detailed information for compound 1522887

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 484.416 | Formula: C23H31Cl2N3O4
  • H donors: 2 H acceptors: 2 LogP: 4.61 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(CCNC(=O)c1cc(Cl)c(cc1OC)NC(=O)COc1ccc(cc1)C)CC.Cl
  • InChi: 1S/C23H30ClN3O4.ClH/c1-5-27(6-2)12-11-25-23(29)18-13-19(24)20(14-21(18)30-4)26-22(28)15-31-17-9-7-16(3)8-10-17;/h7-10,13-14H,5-6,11-12,15H2,1-4H3,(H,25,29)(H,26,28);1H
  • InChiKey: JGWHYJLATPYWNB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0041 0.0438 0.8609
Loa Loa (eye worm) hypothetical protein 0.0044 0.0483 0.0483
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0041 0.0438 1
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0008 0.0011 0.0011
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0209 0.0209
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0209 0.4297
Loa Loa (eye worm) aminopeptidase N 0.0041 0.0438 0.0438
Echinococcus multilocularis transient receptor potential cation channel 0.0351 0.4496 0.4496
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Trypanosoma brucei Aminopeptidase M1, putative 0.0041 0.0438 0.9203
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0041 0.0438 0.861
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Mycobacterium ulcerans hypothetical protein 0.0044 0.0475 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0209 0.0209
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0209 0.0198
Loa Loa (eye worm) hypothetical protein 0.0023 0.0209 0.0209
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Echinococcus multilocularis musashi 0.003 0.0292 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Loa Loa (eye worm) hypothetical protein 0.003 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0025 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0014 0.009 0.009
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0209 0.4268
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0209 0.4297
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Mycobacterium ulcerans beta-lactamase 0.0044 0.0475 1
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.037 0.036
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.023 0.4717
Trichomonas vaginalis penicillin-binding protein, putative 0.0044 0.0475 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.014 0.174 0.174
Mycobacterium tuberculosis Conserved protein 0.0044 0.0475 0.0793
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.011 0.011
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0008 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0475 0.0475
Trypanosoma brucei unspecified product 0.0016 0.0114 0.2213
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0209 0.0209
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0041 0.0438 0.861
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Brugia malayi Peptidase family M1 containing protein 0.0041 0.0438 0.0964
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0608 0.0598
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.023 0.0913
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0041 0.0438 0.8609
Mycobacterium tuberculosis Probable lipase LipE 0.0044 0.0475 0.0793
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Echinococcus granulosus protein kinase c iota type 0.0014 0.0088 0.0088
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0475 0.5
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.009 0.009
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Echinococcus granulosus lamin 0.003 0.0292 0.0292
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0015 0.0104 0.0104
Brugia malayi hypothetical protein 0.0025 0.023 0.0506
Loa Loa (eye worm) hypothetical protein 0.0044 0.0475 0.0475
Echinococcus granulosus intermediate filament protein 0.003 0.0292 0.0292
Mycobacterium tuberculosis Conserved protein 0.0044 0.0475 0.0793
Schistosoma mansoni loxhd1 0.0023 0.0209 0.0198
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0209 0.0209
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Schistosoma mansoni lipoxygenase 0.0098 0.1187 0.1177
Onchocerca volvulus 0.0041 0.0438 0.861
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Loa Loa (eye worm) intermediate filament protein 0.003 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0148 0.1837 0.1837
Brugia malayi beta-lactamase 0.0044 0.0475 0.1045
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0008 0.0011 0.0011
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0041 0.0438 0.9207
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.023 0.0784
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0209 0.0198
Echinococcus multilocularis beta LACTamase domain containing family member 0.0044 0.0475 0.0475
Trichomonas vaginalis D-aminoacylase, putative 0.0044 0.0475 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.023 0.0913
Schistosoma mansoni hypothetical protein 0.0023 0.0209 0.0198
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0209 0.0209
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0044 0.0475 0.0465
Onchocerca volvulus 0.003 0.0292 0.3104
Echinococcus multilocularis protein kinase c iota type 0.0014 0.0088 0.0088
Schistosoma mansoni lipoxygenase 0.014 0.174 0.1731
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0008 0.0011 0.0011
Schistosoma mansoni rab6-interacting 0.0023 0.0209 0.0198
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0041 0.0438 0.9207
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0209 0.4268
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0008 0.0011 0.0011
Brugia malayi beta-lactamase family protein 0.0044 0.0475 0.1045
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0041 0.0438 0.9207
Toxoplasma gondii aminopeptidase N protein 0.0041 0.0438 0.9203
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0041 0.0438 0.8609
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.004 0.0424 0.0424
Loa Loa (eye worm) AGC/AKT protein kinase 0.0008 0.0011 0.0011
Giardia lamblia DINP protein human, muc B family 0.0023 0.0209 0.5
Echinococcus granulosus RUN 0.0023 0.0209 0.0209
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0054 0.0608 0.0608
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0209 0.4638
Trichomonas vaginalis D-aminoacylase, putative 0.0044 0.0475 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.023 0.0784
Echinococcus granulosus protein kinase c epsilon type 0.0015 0.0104 0.0104
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0209 0.0209
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0475 1
Schistosoma mansoni atypical protein kinase C 0.0014 0.0088 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0475 1
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.011 0.0243
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.023 0.0786
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0008 0.0011 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Echinococcus granulosus transient receptor potential cation channel 0.035 0.4489 0.4489
Brugia malayi hypothetical protein 0.0041 0.0438 0.0964
Loa Loa (eye worm) hypothetical protein 0.0038 0.0406 0.0406
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Echinococcus granulosus arachidonate 5 lipoxygenase 0.014 0.174 0.174
Echinococcus granulosus protein kinase C gamma type 0.0048 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.0041 0.0438 0.0438
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0209 0.046
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0044 0.0475 1
Loa Loa (eye worm) AGC/PKN protein kinase 0.0008 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0209 0.0209
Onchocerca volvulus 0.0044 0.0475 1
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0038 0.0406 0.0406
Leishmania major hypothetical protein, conserved 0.0044 0.0475 1
Echinococcus multilocularis dna polymerase eta 0.0023 0.0209 0.0209
Brugia malayi hypothetical protein 0.0355 0.4544 1
Brugia malayi protein kinase C II. 0.0015 0.0104 0.0229
Loa Loa (eye worm) AGC/NDR protein kinase 0.0008 0.0011 0.0011
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Trichomonas vaginalis esterase, putative 0.0044 0.0475 1
Echinococcus multilocularis serotonin receptor 0.0148 0.1837 0.1837
Schistosoma mansoni intermediate filament proteins 0.003 0.0292 0.0281
Echinococcus granulosus biogenic amine 5HT receptor 0.0148 0.1837 0.1837
Echinococcus multilocularis RUN 0.0023 0.0209 0.0209
Echinococcus multilocularis lamin 0.003 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0044 0.0475 0.0475
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0771 1 1
Brugia malayi hypothetical protein 0.0023 0.0209 0.046
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0041 0.0438 0.8609
Schistosoma mansoni biogenic amine (5HT) receptor 0.0148 0.1837 0.1828
Mycobacterium ulcerans esterase/lipase LipP 0.0044 0.0475 1
Echinococcus granulosus dna polymerase kappa 0.0023 0.0209 0.0209
Schistosoma mansoni polycystin 1-related 0.0023 0.0209 0.0198
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0041 0.0438 0.0428
Echinococcus granulosus ankyrin repeat protein 0.0343 0.4398 0.4398
Schistosoma mansoni rab6-interacting 0.0023 0.0209 0.0198
Trypanosoma brucei unspecified product 0.0023 0.0209 0.4268
Loa Loa (eye worm) hypothetical protein 0.0014 0.0083 0.0083
Mycobacterium leprae Probable lipase LipE 0.0044 0.0475 0.5
Trypanosoma brucei aminopeptidase, putative 0.0041 0.0438 0.9203
Onchocerca volvulus 0.0041 0.0438 0.861
Onchocerca volvulus 0.003 0.0292 0.3104
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.037 0.037
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0041 0.0438 0.8609
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0209 0.0209
Mycobacterium tuberculosis Probable hydrolase 0.0044 0.0475 0.0793
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0008 0.0011 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Brugia malayi Peptidase family M1 containing protein 0.0041 0.0438 0.0964
Brugia malayi Protein kinase c protein 2 0.0046 0.0501 0.1103
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0608 0.0598
Echinococcus multilocularis serine:threonine protein kinase N2 0.0008 0.0011 0.0011
Echinococcus multilocularis serine:threonine protein kinase N2 0.0008 0.0011 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0044 0.0475 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0209 0.0209
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0041 0.0438 1
Schistosoma mansoni hypothetical protein 0.0036 0.037 0.036
Brugia malayi TATA binding protein associated factor 0.0041 0.0438 0.0964
Loa Loa (eye worm) hypothetical protein 0.0044 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0148 0.1837 0.1837
Mycobacterium tuberculosis Possible penicillin-binding protein 0.028 0.3566 1
Echinococcus multilocularis RNA directed DNA polymerase 0.0038 0.0406 0.0406
Onchocerca volvulus 0.0041 0.0438 0.861
Loa Loa (eye worm) hypothetical protein 0.0041 0.0438 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0114 0.2213
Brugia malayi Peptidase family M1 containing protein 0.0041 0.0438 0.0964
Echinococcus granulosus lamin dm0 0.003 0.0292 0.0292
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0209 0.0209
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0209 0.4268
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0104 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Trypanosoma brucei Aminopeptidase M1, putative 0.0041 0.0438 0.9203
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Echinococcus granulosus Protein kinase C brain isozyme 0.0054 0.0608 0.0608
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0292 0.0642
Mycobacterium ulcerans aminopeptidase N PepN 0.0041 0.0438 0.8609
Schistosoma mansoni DNA polymerase eta 0.0023 0.0209 0.0198
Loa Loa (eye worm) hypothetical protein 0.0044 0.0475 0.0475
Trichomonas vaginalis D-aminoacylase, putative 0.0044 0.0475 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Brugia malayi hypothetical protein 0.0023 0.0209 0.046
Entamoeba histolytica aminopeptidase, putative 0.0041 0.0438 1
Brugia malayi Protein kinase domain containing protein 0.0008 0.0011 0.0024
Entamoeba histolytica hypothetical protein 0.0036 0.037 0.8409
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0041 0.0438 0.8609
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0343 0.4398 0.4392
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.009 0.009
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0292 0.0292
Echinococcus multilocularis serotonin receptor 0.0148 0.1837 0.1837
Toxoplasma gondii aminopeptidase n, putative 0.0041 0.0438 0.9203
Echinococcus multilocularis serine threonine protein kinase 0.0048 0.0531 0.0531
Brugia malayi hypothetical protein 0.0041 0.0438 0.0964
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Brugia malayi beta-lactamase family protein 0.0044 0.0475 0.1045
Brugia malayi hypothetical protein 0.0036 0.037 0.0814
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0209 0.046
Echinococcus granulosus beta LACTamase domain containing family member 0.0044 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Mycobacterium tuberculosis Conserved protein 0.0044 0.0475 0.0793
Brugia malayi intermediate filament protein 0.003 0.0292 0.0642
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0044 0.0475 0.0793
Entamoeba histolytica hypothetical protein 0.0036 0.037 0.8409
Entamoeba histolytica hypothetical protein 0.0036 0.037 0.8409
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0475 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0044 0.0475 0.0793
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0041 0.0438 0.8609
Toxoplasma gondii ABC1 family protein 0.0044 0.0475 1
Loa Loa (eye worm) peptidase family M1 containing protein 0.0041 0.0438 0.0438
Trypanosoma cruzi aminopeptidase, putative 0.0041 0.0438 0.8609
Loa Loa (eye worm) hypothetical protein 0.0023 0.0209 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0114 0.2213
Brugia malayi Doublecortin family protein 0.0023 0.0209 0.046
Loa Loa (eye worm) hypothetical protein 0.0044 0.0475 0.0475
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0044 0.0475 0.0475
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0049 0.0049
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0041 0.0438 0.8609
Mycobacterium ulcerans aminopeptidase N PepN 0.0041 0.0438 0.8609
Echinococcus granulosus dna polymerase eta 0.0023 0.0209 0.0209
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0049 0.0049
Onchocerca volvulus 0.0044 0.0475 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0008 0.0011 0.0011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0044 0.0475 0.0465
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0209 0.0209
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Echinococcus granulosus NDR protein kinase 0.0008 0.0011 0.0011
Loa Loa (eye worm) beta-lactamase 0.0044 0.0475 0.0475
Mycobacterium ulcerans lipase LipD 0.0044 0.0475 1
Leishmania major hypothetical protein, conserved 0.0025 0.023 0.0784
Loa Loa (eye worm) hypothetical protein 0.0014 0.0083 0.0083
Entamoeba histolytica hypothetical protein 0.0036 0.037 0.8409
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0041 0.0438 0.0438
Brugia malayi Protein kinase domain containing protein 0.0008 0.0011 0.0024
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.023 0.4717
Schistosoma mansoni aminopeptidase A (M01 family) 0.0041 0.0438 0.0428
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0771 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0284 0.0284
Mycobacterium tuberculosis Probable lipase LipD 0.0044 0.0475 0.0793
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0041 0.0438 0.0428
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Schistosoma mansoni hypothetical protein 0.0011 0.0049 0.0038
Mycobacterium tuberculosis Probable esterase LipL 0.0044 0.0475 0.0793
Trichomonas vaginalis AGC family protein kinase 0.0008 0.0011 0.0051
Brugia malayi p70 ribosomal S6 kinase beta 0.0008 0.0011 0.0024
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0008 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0209 0.4268
Schistosoma mansoni lamin 0.003 0.0292 0.0281
Toxoplasma gondii aminopeptidase N, putative 0.0041 0.0438 0.9203
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0475 1
Echinococcus multilocularis serine:threonine protein kinase 38 0.0008 0.0011 0.0011
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0209 0.0209
Brugia malayi Protein kinase domain containing protein 0.0008 0.0011 0.0024
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.037 0.037
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0044 0.0475 0.0793
Echinococcus granulosus RNA directed DNA polymerase 0.0038 0.0406 0.0406
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0771 1 1
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0041 0.0438 0.0438
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0044 0.0475 0.1045
Schistosoma mansoni lamin 0.003 0.0292 0.0281
Onchocerca volvulus 0.0044 0.0475 1
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0008 0.0011 0.0011
Echinococcus granulosus aminopeptidase N 0.0041 0.0438 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0114 0.2213
Brugia malayi hypothetical protein 0.0016 0.0113 0.025
Loa Loa (eye worm) TATA binding protein associated factor 0.0041 0.0438 0.0438
Echinococcus multilocularis aminopeptidase N 0.0041 0.0438 0.0438
Trypanosoma cruzi Aminopeptidase M1, putative 0.0041 0.0438 0.8609
Echinococcus multilocularis lamin dm0 0.003 0.0292 0.0292
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0041 0.0438 0.8609
Loa Loa (eye worm) hypothetical protein 0.0041 0.0438 0.0438
Echinococcus granulosus serine:threonine protein kinase N2 0.0008 0.0011 0.0011
Trypanosoma cruzi aminopeptidase, putative 0.0041 0.0438 0.8609
Trypanosoma brucei unspecified product 0.0016 0.0114 0.2213
Echinococcus multilocularis ankyrin repeat protein 0.0343 0.4398 0.4398
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0041 0.0438 0.9203
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0209 0.4268
Echinococcus multilocularis protein kinase c epsilon type 0.0015 0.0104 0.0104
Brugia malayi Hr1 repeat family protein 0.0008 0.0011 0.0024
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0041 0.0438 0.0428

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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