Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0433 | 1 |
Echinococcus multilocularis | disco interacting protein 2 | 0.0203 | 0.425 | 0.8882 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.0599 | 0.1253 |
Brugia malayi | CXXC zinc finger family protein | 0.0176 | 0.3625 | 0.8528 |
Trypanosoma cruzi | MIZ/SP-RING zinc finger, putative | 0.0039 | 0.037 | 0.5 |
Schistosoma mansoni | phd finger protein | 0.0039 | 0.037 | 0.0772 |
Onchocerca volvulus | 0.0176 | 0.3625 | 0.8388 | |
Schistosoma mansoni | DNA (cytosine-5)-methyltransferase | 0.0225 | 0.4785 | 1 |
Echinococcus multilocularis | PWWP domain containing protein 2A | 0.0039 | 0.037 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0363 | 0.0854 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0045 | 0.0502 | 0.1182 |
Echinococcus granulosus | peregrin | 0.0039 | 0.037 | 0.0772 |
Trypanosoma brucei | cytosine-specific DNA methylase, putative | 0.0225 | 0.4785 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0045 | 0.0502 | 0.1182 |
Brugia malayi | hypothetical protein | 0.0039 | 0.037 | 0.0869 |
Onchocerca volvulus | 0.0203 | 0.425 | 1 | |
Schistosoma mansoni | hepatoma derived growth factor | 0.0039 | 0.037 | 0.0772 |
Brugia malayi | PWWP domain containing protein | 0.0039 | 0.037 | 0.0869 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.0599 | 0.1253 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0045 | 0.0502 | 0.105 |
Echinococcus granulosus | disco interacting protein 2 | 0.0203 | 0.425 | 0.8882 |
Echinococcus multilocularis | cpg binding protein | 0.0176 | 0.3625 | 0.7575 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.037 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.425 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.037 | 0.0772 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0045 | 0.0502 | 0.105 |
Echinococcus granulosus | hepatoma derived growth factor protein | 0.0039 | 0.037 | 0.0772 |
Schistosoma mansoni | cpg binding protein | 0.0176 | 0.3625 | 0.7575 |
Echinococcus granulosus | histone lysine N methyltransferase H3 lysine 36 | 0.0039 | 0.037 | 0.0772 |
Echinococcus multilocularis | hepatoma derived growth factor protein | 0.0039 | 0.037 | 0.0772 |
Schistosoma mansoni | SET domain protein | 0.0039 | 0.037 | 0.0772 |
Echinococcus multilocularis | DNA methyltransferase 2, putative | 0.0225 | 0.4785 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0176 | 0.3625 | 0.7575 |
Schistosoma mansoni | hepatoma derived growth factor | 0.0039 | 0.037 | 0.0772 |
Echinococcus granulosus | cpg binding protein | 0.0176 | 0.3625 | 0.7575 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.037 | 0.0772 |
Leishmania major | modification methylase-like protein | 0.0225 | 0.4785 | 1 |
Trypanosoma cruzi | transcription elongation factor s-II, putative | 0.0039 | 0.037 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.037 | 0.5 |
Echinococcus granulosus | PWWP domain containing protein 2A | 0.0039 | 0.037 | 0.0772 |
Brugia malayi | hypothetical protein | 0.0039 | 0.037 | 0.0869 |
Echinococcus granulosus | PWWP domain containing protein 2A | 0.0039 | 0.037 | 0.0772 |
Schistosoma mansoni | disco-interacting protein 2 (dip2) | 0.0203 | 0.425 | 0.8882 |
Echinococcus granulosus | DNA methyltransferase 2, putative | 0.0225 | 0.4785 | 1 |
Loa Loa (eye worm) | PWWP domain-containing protein | 0.0039 | 0.037 | 0.0869 |
Echinococcus multilocularis | PWWP domain containing protein 2A | 0.0039 | 0.037 | 0.0772 |
Echinococcus multilocularis | histone lysine N methyltransferase, H3 lysine 36 | 0.0039 | 0.037 | 0.0772 |
Brugia malayi | Disco-interacting protein 2 homolog | 0.0203 | 0.425 | 1 |
Trypanosoma cruzi | transcription elongation factor-like protein, putative | 0.0039 | 0.037 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0433 | 1 |
Toxoplasma gondii | C-5 cytosine-specific DNA methylase superfamily protein | 0.0225 | 0.4785 | 0.4585 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0176 | 0.3625 | 0.8528 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.037 | 0.0772 |
Echinococcus multilocularis | peregrin | 0.0039 | 0.037 | 0.0772 |
Entamoeba histolytica | DNA (cytosine-5)-methyltransferase, putative | 0.0225 | 0.4785 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0445 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.037 | 0.0869 |
Schistosoma mansoni | cpg binding protein | 0.0176 | 0.3625 | 0.7575 |
Toxoplasma gondii | DNA methyltransferase 2, putative | 0.0225 | 0.4785 | 0.4585 |
Plasmodium vivax | DNA (cytosine-5)-methyltransferase, putative | 0.0225 | 0.4785 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.