Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | hexokinase, putative | 0.0908 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.1309 | 0.1309 |
Trypanosoma brucei | hexokinase | 0.0908 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.0908 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0908 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0211 | 0.1816 | 0.1816 |
Loa Loa (eye worm) | hexokinase | 0.0569 | 0.6029 | 0.6029 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0193 | 0.1608 | 0.1608 |
Echinococcus multilocularis | hexokinase | 0.0908 | 1 | 1 |
Brugia malayi | hexokinase type II | 0.0289 | 0.2732 | 0.2732 |
Entamoeba histolytica | hexokinase 2 | 0.0908 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0908 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0281 | 0.2641 | 0.2641 |
Loa Loa (eye worm) | hexokinase type II | 0.0908 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.0908 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.0281 | 0.2641 | 0.2641 |
Plasmodium falciparum | hexokinase | 0.0908 | 1 | 0.5 |
Onchocerca volvulus | 0.0908 | 1 | 1 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0211 | 0.1816 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0289 | 0.2732 | 0.2732 |
Onchocerca volvulus | 0.0908 | 1 | 1 | |
Echinococcus multilocularis | hexokinase | 0.0908 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0193 | 0.1608 | 0.1608 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0193 | 0.1608 | 0.1608 |
Leishmania major | hexokinase, putative | 0.0908 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0289 | 0.2732 | 0.2732 |
Treponema pallidum | hexokinase (hxk) | 0.0908 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.018 | 0.1459 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0908 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.0908 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0908 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0908 | 1 | 1 |
Schistosoma mansoni | hexokinase | 0.0908 | 1 | 1 |
Echinococcus multilocularis | hexokinase type 2 | 0.0908 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.0908 | 1 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0193 | 0.1608 | 0.1608 |
Trypanosoma brucei | hexokinase, putative | 0.0908 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.0908 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.0908 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.018 | 0.1459 | 0.5 |
Leishmania major | hexokinase, putative | 0.0908 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0569 | 0.6029 | 0.6029 |
Echinococcus granulosus | hexokinase type 2 | 0.0908 | 1 | 1 |
Onchocerca volvulus | 0.0908 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0619 | 0.6612 | 0.6612 |
Loa Loa (eye worm) | hexokinase | 0.0908 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.