Detailed information for compound 1524826

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 507.494 | Formula: C30H32Cl2N2O
  • H donors: 2 H acceptors: 0 LogP: 7.58 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: Cc1cc(C)cc(c1)C1=C(OCCC2CCCCN2)c2c(NC1)cc(c(c2)c1ccc(cc1)Cl)Cl
  • InChi: 1S/C30H32Cl2N2O/c1-19-13-20(2)15-22(14-19)27-18-34-29-17-28(32)25(21-6-8-23(31)9-7-21)16-26(29)30(27)35-12-10-24-5-3-4-11-33-24/h6-9,13-17,24,33-34H,3-5,10-12,18H2,1-2H3
  • InChiKey: YWHXYUQIWYAANP-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens somatostatin receptor 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus pyroglutamylated rfamide peptide receptor somatostatin receptor 2 369 aa 411 aa 18.7 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus slit 2 protein 0.0035 0.0019 0.0025
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.025 0.0628 0.0661
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0048 0.0056 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0045
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0034 0.0015 0.0019
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0048 0.0055 0.0203
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0057 0.0074
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus granulosus abhydrolase domain containing protein 11 0.003 0.0003 0.0003
Echinococcus granulosus 7TM GPCR rhodopsin 0.0174 0.0412 0.0531
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0084 0.0089
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.007 0.0117 0.0151
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Onchocerca volvulus 0.0174 0.0412 0.1509
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0014 0.003
Schistosoma mansoni hypothetical protein 0.0035 0.0019 0.0032
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0096 0.0191 0.0246
Onchocerca volvulus 0.011 0.023 0.0839
Loa Loa (eye worm) norepinephrine transporter 0.0412 0.1086 0.266
Schistosoma mansoni rab6-interacting 0.0118 0.0253 0.0427
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.021 0.0701
Schistosoma mansoni notch 0.0035 0.0019 0.0032
Onchocerca volvulus 0.0119 0.0257 0.0939
Entamoeba histolytica hypothetical protein 0.003 0.0003 0.0041
Plasmodium falciparum phd finger protein, putative 0.0032 0.001 0.0025
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0039 0.003 0.0099
Brugia malayi jmjC domain containing protein 0.0098 0.0195 0.0435
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0048 0.0055 0.0055
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0057 0.0127
Loa Loa (eye worm) hypothetical protein 0.1468 0.4081 1
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Giardia lamblia NADH oxidase lateral transfer candidate 0.0943 0.2593 1
Trypanosoma brucei hypothetical protein, conserved 0.025 0.0628 0.0658
Leishmania major NADH dehydrogenase, putative 0.025 0.0628 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0099
Leishmania major hypothetical protein, conserved 0.025 0.0628 0.0658
Toxoplasma gondii alpha/beta hydrolase, putative 0.003 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0188 0.045 0.1004
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0014 0.0036
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0057 0.014
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0018 0.0016
Echinococcus granulosus somatostatin receptor 0.0174 0.0412 0.0531
Onchocerca volvulus Chorion peroxidase homolog 0.011 0.023 0.0839
Onchocerca volvulus 0.0174 0.0412 0.1509
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.025 0.0628 0.2098
Leishmania major C-8 sterol isomerase-like protein 0.1151 0.3182 0.3344
Onchocerca volvulus 0.025 0.0628 0.2308
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0149 0.0444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0187 0.0626
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0034 0.0036
Brugia malayi Carboxylesterase family protein 0.0057 0.008 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0118 0.0394
Loa Loa (eye worm) melatonin receptor type 1A 0.0174 0.0412 0.1009
Toxoplasma gondii ABC1 family protein 0.0035 0.0018 0.0051
Brugia malayi RE15519p 0.0174 0.0412 0.0918
Loa Loa (eye worm) hypothetical protein 0.0034 0.0015 0.0037
Echinococcus multilocularis slit 2 protein 0.0035 0.0019 0.0025
Schistosoma mansoni cytochrome P450 0.0048 0.0055 0.0093
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0003 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0114 0.0243 0.0541
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0118 0.0395
Schistosoma mansoni biogenic amine receptor 0.0174 0.0412 0.0694
Plasmodium vivax hypothetical protein, conserved 0.0032 0.001 0.0025
Brugia malayi follicle stimulating hormone receptor 0.0423 0.1119 0.2492
Echinococcus granulosus lysine specific demethylase 5A 0.0098 0.0195 0.0252
Leishmania major hypothetical protein, conserved 0.0081 0.0149 0.0154
Mycobacterium ulcerans short chain dehydrogenase 0.0049 0.0057 0.0211
Echinococcus granulosus neurogenic locus notch protein 0.0035 0.0019 0.0025
Schistosoma mansoni sodium/chloride dependent transporter 0.0071 0.0121 0.0204
Onchocerca volvulus 0.0174 0.0412 0.1509
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.025 0.0628 0.0811
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0039 0.003 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0048 0.0055 0.0053
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0188 0.045 0.1104
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0225 0.0552
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Schistosoma mansoni neuroligin 3 (S09 family) 0.0057 0.008 0.0134
Loa Loa (eye worm) hypothetical protein 0.007 0.0117 0.0286
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0225 0.0552
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0084 0.0281
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.055 0.148 0.4292
Trichomonas vaginalis glucosylceramidase, putative 0.0712 0.1937 0.6468
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0274 0.1047
Onchocerca volvulus 0.003 0.0005 0.0009
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0082 0.0086
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0018 0.0016
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0943 0.2593 0.7788
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0022 0.0023
Echinococcus granulosus allatostatin A receptor 0.0174 0.0412 0.0531
Schistosoma mansoni hypothetical protein 0.025 0.0628 0.1059
Loa Loa (eye worm) carboxylesterase 0.0057 0.008 0.0196
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0082 0.0201
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0072 0.0239
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2761 0.775 1
Echinococcus multilocularis geminin 0.0722 0.1967 0.2538
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0181 0.0431 0.0556
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.021 0.0804
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.021 0.0221
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0025 0.0032
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0025 0.0032
Loa Loa (eye worm) runx1 0.0059 0.0087 0.0213
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.025 0.0628 0.0626
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0173 0.0579
Echinococcus multilocularis 0.0048 0.0055 0.0071
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.025 0.0628 0.2416
Echinococcus multilocularis G protein coupled receptor 139 0.0174 0.0412 0.0531
Echinococcus granulosus neuroligin 0.0057 0.008 0.0103
Echinococcus granulosus delta-like protein 1 0.0035 0.0019 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0187 0.0626
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0039 0.003 0.0099
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.025 0.0628 0.1884
Echinococcus granulosus tumor protein p63 0.0366 0.0957 0.1234
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0164 0.0384 0.0495
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0124 0.0271 0.0349
Plasmodium vivax glutathione reductase, putative 0.1203 0.3329 1
Echinococcus granulosus voltage gated potassium channel 0.0041 0.0035 0.0045
Onchocerca volvulus 0.0112 0.0235 0.0858
Trypanosoma brucei ABC transporter, putative 0.0032 0.0008 0.0006
Trypanosoma cruzi ABC transporter, putative 0.0032 0.0008 0.0009
Echinococcus multilocularis glutamate synthase 0.025 0.0628 0.0811
Echinococcus granulosus neuropeptides capa receptor 0.0174 0.0412 0.0531
Echinococcus granulosus jun protein 0.0345 0.0897 0.1158
Trichomonas vaginalis disulfide oxidoreductase, putative 0.025 0.0628 0.2098
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Schistosoma mansoni neuropeptide receptor 0.0174 0.0412 0.0694
Schistosoma mansoni growth hormone secretagogue receptor 0.0174 0.0412 0.0694
Onchocerca volvulus Netrin receptor homolog 0.0055 0.0074 0.0264
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0274 0.0818
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0014 0.0018
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.025 0.0628 0.0658
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.021 0.0218
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0292 0.0492
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Echinococcus granulosus thioredoxin glutathione reductase 0.1203 0.3331 0.4298
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0057 0.014
Echinococcus multilocularis abhydrolase domain containing protein 11 0.003 0.0003 0.0003
Echinococcus granulosus inositol monophosphatase 1 0.023 0.0572 0.0738
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0225 0.0647
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0225 0.0753
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0041 0.0035 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0173 0.0579
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.007 0.0117 0.0151
Echinococcus multilocularis neuropeptide s receptor 0.1121 0.3098 0.3997
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Brugia malayi Carboxylesterase family protein 0.0336 0.0873 0.1945
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0096 0.019 0.0246
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0048 0.0055 0.0203
Echinococcus multilocularis protein jagged 1 0.0035 0.0019 0.0025
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0943 0.2593 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0117 0.0286
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0136 0.0175
Brugia malayi Carboxylesterase family protein 0.0057 0.008 0.0178
Echinococcus granulosus neurogenic locus protein delta 0.0035 0.0019 0.0025
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0048 0.0055 0.0203
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0018 0.0041
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0225 0.0864
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0072 0.0122 0.0157
Brugia malayi Blistered cuticle protein 3 0.0187 0.045 0.1003
Echinococcus multilocularis neurogenic locus protein delta 0.0035 0.0019 0.0025
Loa Loa (eye worm) G-protein coupled receptor 0.0174 0.0412 0.1009
Schistosoma mansoni notch 0.0035 0.0019 0.0032
Echinococcus granulosus neurogenic locus notch protein 4 0.0035 0.0019 0.0025
Echinococcus multilocularis serotonin receptor 0.0432 0.1144 0.1477
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0003 0.0009
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.0557 0.0554
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0173 0.0579
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0057 0.0074
Loa Loa (eye worm) hypoxia-induced factor 1 0.0467 0.1243 0.3046
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0057 0.0201
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0174 0.0412 0.0694
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0057 0.0074
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0174 0.0412 0.0694
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1243 0.3444 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0048 0.0055 0.0161
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0114 0.0243 0.3861
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0206 0.0503 0.0501
Treponema pallidum oxidoreductase 0.025 0.0628 0.2419
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0022 0.0028
Echinococcus multilocularis abhydrolase domain containing protein 16A 0.003 0.0003 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.0174 0.0412 0.0531
Schistosoma mansoni hypothetical protein 0.0174 0.0412 0.0694
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0181 0.0431 0.096
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0039 0.003 0.0038
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.021 0.0626
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0018 0.0019
Plasmodium vivax ABC transporter G family member 2, putative 0.0032 0.0008 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0057 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0187 0.0626
Onchocerca volvulus 0.0056 0.0076 0.0271
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.018 0.06
Onchocerca volvulus 0.0057 0.008 0.0285
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0943 0.2593 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) hypothetical protein 0.0412 0.1086 0.266
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0336 0.0873 0.1471
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0165 0.0388 0.142
Onchocerca volvulus Peroxidasin homolog 0.011 0.023 0.0839
Echinococcus granulosus acetylcholinesterase 0.0336 0.0873 0.1126
Loa Loa (eye worm) hypothetical protein 0.1468 0.4081 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.011 0.0369
Onchocerca volvulus 0.0049 0.0057 0.0201
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Chlamydia trachomatis thioredoxin reductase 0.025 0.0628 0.2419
Echinococcus granulosus serotonin transporter 0.0412 0.1086 0.1401
Loa Loa (eye worm) hypothetical protein 0.0117 0.0251 0.0614
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.025 0.0628 0.0658
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0455 0.1208 0.1559
Schistosoma mansoni ap endonuclease 0.0058 0.0084 0.0142
Onchocerca volvulus 0.011 0.023 0.0839
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.021 0.0514
Brugia malayi Serotonin receptor 0.0174 0.0412 0.0918
Schistosoma mansoni hypothetical protein 0.0035 0.0019 0.0032
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.025 0.0628 0.1884
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0072 0.0122 0.0128
Echinococcus multilocularis ATP binding cassette sub family G 0.0032 0.0008 0.0011
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.007 0.0117 0.0445
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.0191 0.0321
Schistosoma mansoni neuropeptide f receptor 76f 0.0174 0.0412 0.0694
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0174 0.0412 0.0918
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0018 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0132 0.0442
Echinococcus granulosus chromobox protein 1 0.0082 0.015 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0057 0.0127
Brugia malayi Uncoordinated protein 44 0.0044 0.0043 0.0096
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0039 0.003 0.0099
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.025 0.0628 0.0811
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0048 0.0055 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3381 0.9508 1
Trichomonas vaginalis glucosylceramidase, putative 0.0712 0.1937 0.6468
Onchocerca volvulus 0.0174 0.0412 0.1509
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0061 0.009 0.0267
Schistosoma mansoni neuropeptide receptor 0.0174 0.0412 0.0694
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.025 0.0628 0.2416
Loa Loa (eye worm) neuropeptide F receptor 0.0174 0.0412 0.1009
Trichomonas vaginalis adenylate cyclase, putative 0.0039 0.003 0.0099
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0014 0.0014
Loa Loa (eye worm) hydrolase 0.003 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0114 0.0241 0.059
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0174 0.0412 0.0694
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Brugia malayi PAS domain containing protein 0.0151 0.0346 0.0772
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0048 0.0055 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Echinococcus multilocularis chromobox protein 1 0.0082 0.015 0.0193
Echinococcus multilocularis neuropeptide receptor 0.0174 0.0412 0.0531
Brugia malayi 6-phosphofructokinase 0.0109 0.0226 0.0505
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0032 0.0008 0.0014
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0057 0.0074
Echinococcus granulosus notch 0.0035 0.0019 0.0025
Brugia malayi Hypothetical 54.7 kDa protein F37A4.1 in chromosome III 0.003 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.007 0.0117 0.0286
Echinococcus granulosus ATP binding cassette sub family G 0.0032 0.0008 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0274 0.0671
Giardia lamblia ABC transporter 0.0031 0.0007 0.0022
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0014 0.0011
Trichomonas vaginalis protein kinase inhibitor, putative 0.0068 0.011 0.0368
Brugia malayi beta-lactamase family protein 0.0035 0.0018 0.0041
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.025 0.0628 0.2098
Onchocerca volvulus 0.0035 0.0018 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.1085 0.2995 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.026
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0057 0.0074
Schistosoma mansoni notch 0.0035 0.0019 0.0032
Leishmania major trypanothione reductase 0.1203 0.3329 0.35
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0102 0.163
Onchocerca volvulus Peroxidase homolog 0.011 0.023 0.0839
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2486 0.6969 0.7329
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.003 0.0003 0.0003
Brugia malayi Probable DNA topoisomerase II 0.0238 0.0594 0.1324
Echinococcus granulosus nuclear factor of activated T cells 5 0.0225 0.0556 0.0717
Schistosoma mansoni jun-related protein 0.0281 0.0714 0.1204
Trypanosoma cruzi hypothetical protein, conserved 0.025 0.0628 0.0661
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0048 0.0055 0.0053
Mycobacterium ulcerans NADH dehydrogenase 0.025 0.0628 0.2416
Brugia malayi phosphofructokinase 0.0108 0.0225 0.0502
Echinococcus multilocularis survival motor neuron protein 1 0.0727 0.1979 0.2554
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Giardia lamblia ENC6 protein 0.003 0.0003 0.0004
Loa Loa (eye worm) acetylcholinesterase 1 0.0336 0.0873 0.2139
Schistosoma mansoni netrin receptor unc5 0.0048 0.0054 0.0091
Echinococcus multilocularis neurogenic locus protein delta 0.0035 0.0019 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0057 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0173 0.0579
Loa Loa (eye worm) hypothetical protein 0.0057 0.0079 0.0194
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.001 0.0013
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1203 0.3329 0.3328
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.023 0.0572 0.2033
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0943 0.2593 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.023 0.0572 0.0599
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0048 0.0055 0.0203
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0943 0.2593 0.2725
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0015 0.0037
Onchocerca volvulus 0.0154 0.0354 0.1297
Brugia malayi G protein-coupled receptor 0.0174 0.0412 0.0918
Echinococcus multilocularis ATP binding cassette sub family G 0.0032 0.0008 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Echinococcus multilocularis protein jagged 2 0.0035 0.0019 0.0025
Mycobacterium ulcerans hypothetical protein 0.0035 0.0018 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.011 0.0369
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.023 0.0572 0.1713
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0057 0.0127
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.025 0.0628 0.0811
Echinococcus granulosus ATP binding cassette sub family G 0.0032 0.0008 0.0011
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0051 0.0063 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0292 0.0492
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0943 0.2593 0.5777
Brugia malayi hypoxia-induced factor 1 0.0467 0.1243 0.2769
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Brugia malayi Delta serrate ligand family protein 0.0035 0.0019 0.0043
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0014 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0063 0.021
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0035 0.0017 0.0016
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0225 0.0556 0.0717
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0048 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0077 0.0136 0.2157
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0015 0.0025
Brugia malayi TAR-binding protein 0.0132 0.0292 0.065
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.021 0.0218
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0032 0.0008 0.0022
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1085 0.2995 0.7339
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0072 0.0122 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0063 0.021
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0114 0.0243 0.0253
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0084 0.1341
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0292 0.0492
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0181 0.0431 0.0428
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0035 0.0019 0.0061
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0174 0.0412 0.1009
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0072 0.0122 0.0126
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0274 0.0353
Entamoeba histolytica DNA topoisomerase II, putative 0.0238 0.0594 0.9459
Leishmania major hypothetical protein, conserved 0.025 0.0628 0.0658
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0061 0.009 0.0136
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0048 0.0055 0.0053
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Echinococcus multilocularis serine protein kinase ATM 0.0044 0.0044 0.0056
Echinococcus multilocularis fmrfamide receptor 0.0174 0.0412 0.0531
Echinococcus multilocularis peroxidasin 0.0114 0.0241 0.0311
Echinococcus multilocularis sex peptide receptor 0.0174 0.0412 0.0531
Brugia malayi EGF-like domain containing protein 0.0035 0.0019 0.0043
Echinococcus granulosus neuropeptide s receptor 0.1121 0.3098 0.3997
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.007 0.0117 0.0197
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0943 0.2593 0.2727
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0057 0.0074
Echinococcus granulosus lamin 0.0056 0.0076 0.0098
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0181 0.0431 0.045
Echinococcus granulosus alpha 1A adrenergic receptor 0.0174 0.0412 0.0531
Trichomonas vaginalis glucosylceramidase, putative 0.0712 0.1937 0.6468
Plasmodium falciparum LCCL domain-containing protein 0.0118 0.0253 0.0757
Brugia malayi jmjC domain containing protein 0.0164 0.0384 0.0855
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.025 0.0628 0.0658
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0048 0.0055 0.0203
Toxoplasma gondii Erv1 / Alr family protein 0.0072 0.0122 0.0362
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0084 0.0109
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0405 0.1068 0.3096
Trypanosoma cruzi DNA topoisomerase II, putative 0.0238 0.0594 0.0625
Trichomonas vaginalis esterase, putative 0.0035 0.0018 0.0062
Echinococcus granulosus g-protein coupled receptor 0.0174 0.0412 0.0531
Echinococcus granulosus lipoxygenase domain containing protein 0.0118 0.0253 0.0327
Plasmodium vivax thioredoxin reductase, putative 0.1203 0.3329 1
Schistosoma mansoni acetylcholinesterase 0.0057 0.008 0.0134
Echinococcus granulosus sodium and chloride dependent glycine 0.007 0.0117 0.0151
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0174 0.0412 0.0694
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0943 0.2593 0.7788
Loa Loa (eye worm) hypothetical protein 0.0124 0.0271 0.0664
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Brugia malayi Inositol-1 0.023 0.0572 0.1273
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0057 0.0096
Onchocerca volvulus 0.0148 0.0339 0.124
Echinococcus multilocularis acetylcholinesterase 0.0336 0.0873 0.1126
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0099
Schistosoma mansoni amine GPCR 0.0174 0.0412 0.0694
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0124 0.0415
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0274 0.1047
Mycobacterium ulcerans hypothetical protein 0.025 0.0628 0.2416
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0051 0.0063 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0057 0.0074
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.025 0.0628 0.0626
Echinococcus granulosus serotonin receptor 0.0174 0.0412 0.0531
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0238 0.0594 0.1324
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0025 0.0056
Brugia malayi Cytochrome P450 family protein 0.0089 0.0172 0.0382
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0149 0.0157
Trichomonas vaginalis disulfide oxidoreductase, putative 0.025 0.0628 0.2098
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0054 0.012
Brugia malayi UPF0017 protein CG3488 0.003 0.0003 0.0006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0071 0.0119 0.0292
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0225 0.0753
Onchocerca volvulus 0.0174 0.0412 0.1509
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0412 0.0531
Schistosoma mansoni hypothetical protein 0.011 0.023 0.0387
Brugia malayi nuclear receptor NHR-88 0.0049 0.0057 0.0127
Echinococcus granulosus neuropeptide Y receptor 0.0174 0.0412 0.0531
Trichomonas vaginalis PIKK family atypical protein kinase 0.0114 0.0243 0.081
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0225 0.0234
Echinococcus granulosus aryl hydrocarbon receptor 0.0039 0.003 0.0038
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.021 0.0271
Trypanosoma brucei DNA topoisomerase ii 0.0182 0.0434 0.0454
Loa Loa (eye worm) animal heme peroxidase 0.011 0.023 0.0564
Brugia malayi ORL1-like opioid receptor 0.0174 0.0412 0.0918
Echinococcus granulosus neuropeptide Y receptor 0.0174 0.0412 0.0531
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0943 0.2593 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0034 0.0016 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0943 0.2593 0.7788
Brugia malayi Thioredoxin reductase 0.1203 0.3329 0.7417
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0001 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0048 0.0055 0.0053
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0014 0.0018
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0015 0.0025
Brugia malayi Cadherin domain containing protein 0.0035 0.0019 0.0043
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.0286
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0174 0.0412 0.0531
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Echinococcus multilocularis sodium and chloride dependent glycine 0.007 0.0117 0.0151
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.025 0.0628 0.2416
Trypanosoma cruzi DNA topoisomerase II, putative 0.0238 0.0594 0.0625
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0015 0.005
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0174 0.0412 0.1009
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0039 0.003 0.0073
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.025 0.0628 0.1884
Trypanosoma cruzi DNA repair protein, putative 0.0035 0.0017 0.0018
Brugia malayi Cytochrome P450 family protein 0.0058 0.0082 0.0183
Loa Loa (eye worm) cytochrome P450 0.0048 0.0055 0.0135
Schistosoma mansoni survival motor neuron protein 0.0148 0.0339 0.0571
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Leishmania major cytochrome p450-like protein 0.0048 0.0055 0.0055
Brugia malayi Protein kinase domain containing protein 0.0045 0.0047 0.0105
Brugia malayi EGF-like domain containing protein 0.0035 0.0019 0.0043
Plasmodium vivax hypothetical protein, conserved 0.003 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.0866 0.2374 0.529
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0048 0.0055 0.0053
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0225 0.038
Brugia malayi hypothetical protein 0.0154 0.0354 0.0789
Echinococcus granulosus neuropeptide receptor 0.0174 0.0412 0.0531
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.0292 0.065
Schistosoma mansoni hydrolase 0.003 0.0003 0.0004
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0188 0.045 0.0581
Echinococcus multilocularis neural cadherin 0.0035 0.0019 0.0025
Echinococcus granulosus single minded 2 0.0119 0.0255 0.0329
Echinococcus multilocularis g-protein coupled receptor 0.0174 0.0412 0.0531
Loa Loa (eye worm) DnaJ domain-containing protein 0.0068 0.011 0.027
Echinococcus granulosus g protein coupled receptor 0.0174 0.0412 0.0531
Onchocerca volvulus Peroxidase homolog 0.011 0.023 0.0839
Trichomonas vaginalis glucosylceramidase, putative 0.0712 0.1937 0.6468
Chlamydia trachomatis DNA gyrase subunit A 0.0048 0.0056 0.0209
Onchocerca volvulus 0.0057 0.008 0.0285
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0225 0.0291
Mycobacterium ulcerans lipase LipD 0.0035 0.0018 0.0061
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0057 0.0096
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.025 0.0628 0.14
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0943 0.2593 0.2725
Brugia malayi MH2 domain containing protein 0.0125 0.0274 0.061
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0136 0.0175
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0412 0.0531
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0412 0.0531
Loa Loa (eye worm) phosphatidylinositol 3 0.0114 0.0243 0.0595
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0057 0.0127
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.021 0.0218
Brugia malayi EGF-like domain containing protein 0.0035 0.0019 0.0043
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0058 0.0082 0.0307
Onchocerca volvulus Neuropeptide F receptor homolog 0.0174 0.0412 0.1509
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.025 0.0628 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.025 0.0628 0.1884
Schistosoma mansoni lamin 0.0056 0.0076 0.0128
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0225 0.0223
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.025 0.0628 0.1884
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0044 0.0044 0.0046
Schistosoma mansoni DNA topoisomerase II 0.0238 0.0594 0.1002
Mycobacterium tuberculosis Conserved protein 0.0035 0.0018 0.0016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.026
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0225 0.0291
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0076 0.0187
Mycobacterium tuberculosis Conserved protein 0.0035 0.0018 0.0016
Echinococcus granulosus protein jagged 1 0.0035 0.0019 0.0025
Onchocerca volvulus 0.0473 0.126 0.4635
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0102 0.0173
Toxoplasma gondii target of rapamycin (TOR), putative 0.009 0.0173 0.0517
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0174 0.0412 0.0694
Onchocerca volvulus 0.0118 0.0253 0.0925
Loa Loa (eye worm) hypothetical protein 0.0178 0.0423 0.1036
Onchocerca volvulus 0.011 0.023 0.0839
Loa Loa (eye worm) hypothetical protein 0.0336 0.0873 0.2139
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0032 0.0008 0.0006
Schistosoma mansoni disulfide oxidoreductase 0.025 0.0628 0.1059
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0174 0.0412 0.0531
Plasmodium falciparum ferrodoxin reductase-like protein 0.025 0.0628 0.1884
Schistosoma mansoni BC026374 protein (S09 family) 0.0057 0.008 0.0134
Brugia malayi hypothetical protein 0.0081 0.0149 0.0332
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Loa Loa (eye worm) hypothetical protein 0.0057 0.0079 0.0194
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0095 0.0188 0.0195
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0943 0.2593 1
Schistosoma mansoni hypothetical protein 0.0077 0.0136 0.0229
Loa Loa (eye worm) hypothetical protein 0.0038 0.0025 0.0062
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0044 0.0043 0.0055
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0048 0.0055 0.0203
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.025 0.0628 0.14
Treponema pallidum replicative DNA helicase (dnaB) 0.0405 0.1068 0.4116
Loa Loa (eye worm) heterochromatin protein 1 0.0082 0.015 0.0367
Loa Loa (eye worm) hypothetical protein 0.0659 0.1789 0.4383
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0057 0.0096
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0018 0.0046
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0082 0.0201
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0188 0.045 0.1651
Schistosoma mansoni amine GPCR 0.0174 0.0412 0.0694
Schistosoma mansoni amine GPCR 0.0174 0.0412 0.0694
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0063 0.0224
Brugia malayi Dopamine receptor protein 1 0.0174 0.0412 0.0918
Onchocerca volvulus 0.0035 0.0019 0.0061
Schistosoma mansoni coup transcription factor 0.0049 0.0057 0.0096
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.025 0.0628 0.1818
Loa Loa (eye worm) beta-lactamase 0.0035 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0084 0.0315
Loa Loa (eye worm) hypothetical protein 0.0178 0.0423 0.1036
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0084 0.032
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0174 0.0412 0.0531
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0063 0.021
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0022 0.0023
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0943 0.2593 0.3346
Brugia malayi Dopamine receptor 0.0174 0.0412 0.0918
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0432 0.1144 0.2804
Trichomonas vaginalis disulfide oxidoreductase, putative 0.025 0.0628 0.2098
Giardia lamblia Glutamate synthase 0.025 0.0628 0.2419
Loa Loa (eye worm) animal heme peroxidase 0.011 0.023 0.0564
Trichomonas vaginalis glucosylceramidase, putative 0.0712 0.1937 0.6468
Echinococcus granulosus neuropeptide FF receptor 2 0.0174 0.0412 0.0531
Schistosoma mansoni hypothetical protein 0.0036 0.0022 0.0037
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.025 0.0628 0.2416
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0061 0.009 0.0088
Mycobacterium tuberculosis Probable dehydrogenase 0.055 0.148 0.1478
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0412 0.0531
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0292 0.0492
Plasmodium vivax hypothetical protein, conserved 0.003 0.0003 0.0003
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0015 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.1085 0.2995 1
Mycobacterium ulcerans monoxygenase 0.025 0.0628 0.2416
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0063 0.014
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0001 0.0005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.025 0.0628 0.2098
Brugia malayi ecdysteroid receptor 0.0049 0.0057 0.0127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3381 0.9508 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0693 0.1883 0.4196
Loa Loa (eye worm) hypothetical protein 0.0041 0.0035 0.0086
Toxoplasma gondii thioredoxin reductase 0.1203 0.3329 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0943 0.2593 0.3346
Plasmodium vivax DNA gyrase subunit A, putative 0.0048 0.0056 0.0163
Loa Loa (eye worm) ab-hydrolase associated lipase region family protein 0.003 0.0003 0.0006
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0096 0.0191 0.0246
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.025 0.0628 0.0658
Entamoeba histolytica disulphide oxidoreductase, putative 0.025 0.0628 1
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Plasmodium vivax multidomain scavenger receptor, putative 0.0118 0.0253 0.0757
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0102 0.0251
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0136 0.0229
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0174 0.0412 0.0531
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0014 0.0012
Brugia malayi Augmenter of liver regeneration 0.0072 0.0122 0.0272
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0174 0.0412 0.0531
Loa Loa (eye worm) TOPoisomerase family member 0.0238 0.0594 0.1457
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0057 0.0074
Trichomonas vaginalis glutamate synthase, putative 0.025 0.0628 0.2098
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.025 0.0628 0.0658
Echinococcus granulosus protein jagged 2 0.0035 0.0019 0.0025
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.025 0.0628 0.1818
Echinococcus granulosus biogenic amine 5HT receptor 0.0174 0.0412 0.0531
Schistosoma mansoni notch 0.0035 0.0019 0.0032
Leishmania major hypothetical protein, conserved 0.0035 0.0018 0.0017
Brugia malayi Death domain containing protein 0.0044 0.0043 0.0096
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0048 0.0055 0.0203
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0084 0.0089
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Schistosoma mansoni lamin 0.0056 0.0076 0.0128
Brugia malayi Animal haem peroxidase family protein 0.011 0.023 0.0513
Trypanosoma cruzi DNA repair protein, putative 0.0035 0.0017 0.0018
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0048 0.0055 0.0203
Schistosoma mansoni hypothetical protein 0.0148 0.0339 0.0571
Schistosoma mansoni lozenge 0.0059 0.0087 0.0146
Onchocerca volvulus Alhambra homolog 0.0032 0.001 0.0027
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.055 0.148 0.1478
Trichomonas vaginalis mercuric reductase, putative 0.0943 0.2593 0.8659
Brugia malayi EGF-like domain containing protein 0.0035 0.0019 0.0043
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0247 0.0619 0.0649
Echinococcus multilocularis notch 0.0035 0.0019 0.0025
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0076 0.0187
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0044 0.0044 0.0074
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Brugia malayi hypothetical protein 0.011 0.023 0.0513
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0057 0.014
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0048 0.0055 0.0203
Loa Loa (eye worm) hypothetical protein 0.0086 0.0162 0.0396
Brugia malayi Dopamine receptor protein 2 0.0174 0.0412 0.0918
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0225 0.0552
Trichomonas vaginalis glucosylceramidase, putative 0.1085 0.2995 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2845 0.7987 0.84
Schistosoma mansoni hypothetical protein 0.0032 0.001 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0099
Brugia malayi Cadherin domain containing protein 0.0035 0.0019 0.0043
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0165 0.0388 0.142
Echinococcus multilocularis acetylcholinesterase 0.0336 0.0873 0.1126
Brugia malayi notch-like transmembrane receptor 0.0035 0.0019 0.0043
Loa Loa (eye worm) glutathione reductase 0.1203 0.3329 0.8158
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0072 0.0122 0.0362
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.025 0.0628 0.1884
Trypanosoma cruzi NADH dehydrogenase, putative 0.025 0.0628 0.0661
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.025 0.0628 0.0661
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0174 0.0412 0.0531
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0423 0.1119 0.2741
Brugia malayi M-phase phosphoprotein, mpp8 0.0119 0.0257 0.0573
Echinococcus granulosus fmrfamide receptor 0.0174 0.0412 0.0531
Echinococcus granulosus carboxylesterase 5A 0.0336 0.0873 0.1126
Brugia malayi Melatonin receptor type 1A 0.0174 0.0412 0.0918
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0018 0.0016
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0039 0.003 0.0099
Echinococcus multilocularis neuropeptide FF receptor 2 0.0174 0.0412 0.0531
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0057 0.0127
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.0346
Brugia malayi hypothetical protein 0.0077 0.0136 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0057 0.0127
Echinococcus granulosus abhydrolase domain containing protein 3 0.003 0.0003 0.0003
Echinococcus granulosus dnaJ subfamily C 6 0.0068 0.011 0.0142
Onchocerca volvulus 0.0035 0.0018 0.0058
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0102 0.0108
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.025 0.0628 0.0811
Schistosoma mansoni sodium/chloride dependent transporter 0.007 0.0117 0.0197
Echinococcus multilocularis thioredoxin glutathione reductase 0.1203 0.3331 0.4298
Loa Loa (eye worm) doublecortin family protein 0.0118 0.0253 0.0621
Brugia malayi bHLH-PAS transcription factor 0.0112 0.0235 0.0524
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0057 0.0074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Trypanosoma cruzi hypothetical protein, conserved 0.025 0.0628 0.0661
Schistosoma mansoni family S33 non-peptidase homologue (S33 family) 0.003 0.0003 0.0004
Brugia malayi EGF-like domain containing protein 0.0035 0.0019 0.0043
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.007 0.0117 0.0197
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0051 0.0063 0.0081
Entamoeba histolytica hypothetical protein 0.0077 0.0136 0.2157
Loa Loa (eye worm) hypothetical protein 0.0117 0.0251 0.0614
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.012 0.0258 0.0333
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0194 0.0475
Trypanosoma cruzi NADH dehydrogenase, putative 0.025 0.0628 0.0661
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.021 0.0701
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0181 0.0431 0.0556
Onchocerca volvulus 0.0148 0.0337 0.1235
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0118 0.0394
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0188 0.045 0.0581
Loa Loa (eye worm) hypothetical protein 0.0039 0.003 0.0073
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0048 0.0055 0.0053
Echinococcus granulosus serine protein kinase ATM 0.0044 0.0044 0.0056
Entamoeba histolytica myo-inositol monophosphatase, putative 0.023 0.0572 0.9095
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0044 0.0097
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0412 0.0694
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0149 0.0157
Schistosoma mansoni alpha-1 adrenergic receptor 0.0174 0.0412 0.0694
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0274 0.0353
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0455 0.1208 0.1559
Loa Loa (eye worm) hypothetical protein 0.003 0.0005 0.0012
Echinococcus granulosus neuropeptide receptor A26 0.1121 0.3098 0.3997
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0084 0.0281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0174 0.0412 0.0694
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0036 0.0022 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2845 0.7987 0.84
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0048 0.0055 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.011 0.0369
Brugia malayi GnHR receptor homolog 0.0174 0.0412 0.0918
Mycobacterium ulcerans recombinase A 0.0113 0.024 0.0915
Schistosoma mansoni gliotactin 0.0057 0.008 0.0134
Brugia malayi steroid hormone receptor 0.0049 0.0057 0.0127
Trypanosoma brucei trypanothione reductase 0.1203 0.3329 0.35
Echinococcus multilocularis Polycystic kidney disease protein 0.0118 0.0253 0.0327
Brugia malayi beta-lactamase family protein 0.0035 0.0018 0.0041
Schistosoma mansoni lipoxygenase 0.0455 0.1208 0.2036
Trichomonas vaginalis glucosylceramidase, putative 0.1085 0.2995 1
Loa Loa (eye worm) CYP4Cod1 0.0058 0.0082 0.0201
Giardia lamblia DNA topoisomerase II 0.0227 0.0561 0.216
Schistosoma mansoni neuropeptide receptor 0.0174 0.0412 0.0694
Toxoplasma gondii NADPH-glutathione reductase 0.0943 0.2593 0.7788
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0015 0.0019
Schistosoma mansoni hypothetical protein 0.0035 0.0019 0.0032
Toxoplasma gondii homoserine O-acetyltransferase, putative 0.003 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0048 0.0055 0.0203
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0225 0.0753
Echinococcus multilocularis aryl hydrocarbon receptor 0.0039 0.003 0.0038
Loa Loa (eye worm) hypothetical protein 0.007 0.0117 0.0286
Trypanosoma brucei C-8 sterol isomerase, putative 0.1151 0.3182 0.3344
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0057 0.0074
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0412 0.0694
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0048 0.0055 0.0053
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0048 0.0055 0.0203
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0072 0.0122 0.0128
Schistosoma mansoni amine GPCR 0.156 0.4343 0.7321
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0034 0.0015 0.0019
Mycobacterium ulcerans DNA gyrase subunit B 0.0061 0.009 0.0338
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0001 0.0005
Onchocerca volvulus 0.0174 0.0412 0.1509
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0149 0.0444
Schistosoma mansoni voltage-gated potassium channel 0.0103 0.0211 0.0355
Loa Loa (eye worm) hypothetical protein 0.0588 0.1586 0.3887
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0271 0.0809
Mycobacterium leprae putative cytochrome p450 0.0048 0.0055 0.0153
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0057 0.0074
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.025 0.0628 0.1818
Schistosoma mansoni hypothetical protein 0.0118 0.0253 0.0427
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0048 0.0055 0.0203
Echinococcus granulosus neurogenic locus notch protein 0.0035 0.0019 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0103 0.0211 0.0355
Plasmodium falciparum thioredoxin reductase 0.1203 0.3329 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0057 0.0074
Echinococcus multilocularis transfer RNA-Lys 0.0112 0.0235 0.0304
Trypanosoma cruzi hydrolase-like protein, putative 0.003 0.0003 0.0003
Onchocerca volvulus 0.0057 0.008 0.0285
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2486 0.6969 0.7329
Loa Loa (eye worm) hypothetical protein 0.007 0.0117 0.0286
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0018 0.0016
Onchocerca volvulus 0.0174 0.0412 0.1509
Trichomonas vaginalis myo inositol monophosphatase, putative 0.023 0.0572 0.1909
Loa Loa (eye worm) hypothetical protein 0.0151 0.0347 0.085
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0048 0.0055 0.0203
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0412 0.0531
Brugia malayi Calcium binding EGF domain containing protein 0.0035 0.0019 0.0043
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.025 0.0628 0.0626
Schistosoma mansoni jumonji domain containing protein 0.0142 0.0322 0.0543
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0057 0.0074
Echinococcus multilocularis serotonin transporter 0.0412 0.1086 0.1401
Brugia malayi AKH receptor 0.0174 0.0412 0.0918
Loa Loa (eye worm) abhydrolase domain-containing protein 2 0.003 0.0003 0.0006
Onchocerca volvulus 0.0174 0.0412 0.1509
Loa Loa (eye worm) hypothetical protein 0.0727 0.1979 0.485
Schistosoma mansoni hypothetical protein 0.0038 0.0025 0.0043
Loa Loa (eye worm) hypothetical protein 0.0412 0.1086 0.266
Brugia malayi Cyclic-nucleotide gated cation channel 0.0034 0.0015 0.0033
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0057 0.0074
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.025 0.0628 0.0811
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0225 0.3587
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0102 0.0132
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.007 0.0117 0.0197
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0015 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0412 0.0694
Echinococcus multilocularis BC026374 protein (S09 family) 0.0057 0.008 0.0103
Brugia malayi chromobox protein homolog 3 0.0051 0.0063 0.0141
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.025 0.0628 0.0811
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0032 0.0008 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0084 0.0109
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0057 0.0201
Trichomonas vaginalis glucosylceramidase, putative 0.075 0.2046 0.6831
Schistosoma mansoni notch 0.0036 0.002 0.0034
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0039 0.003 0.0038
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Echinococcus multilocularis microtubule associated protein 2 0.2121 0.5933 0.7655
Schistosoma mansoni notch 0.0035 0.0019 0.0032
Entamoeba histolytica glutamate synthase beta subunit, putative 0.025 0.0628 1
Brugia malayi glutamate synthase 0.025 0.0628 0.14
Mycobacterium ulcerans beta-lactamase 0.0035 0.0018 0.0061
Schistosoma mansoni hypothetical protein 0.0722 0.1967 0.3316
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0018 0.0016
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0034 0.0036
Echinococcus granulosus G protein coupled receptor 139 0.0174 0.0412 0.0531
Treponema pallidum NADH oxidase 0.0943 0.2593 1
Echinococcus multilocularis dnaJ subfamily C 6 0.0068 0.011 0.0142
Brugia malayi hypothetical protein 0.012 0.0258 0.0576
Onchocerca volvulus 0.0986 0.2715 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0018 0.0062
Brugia malayi Heterochromatin protein 1 0.0082 0.015 0.0334
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0194 0.0326
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0173 0.0579
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.025 0.0628 0.0626
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0271 0.0456
Echinococcus granulosus neural cadherin 0.0035 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0235 0.0585 0.1433
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.007 0.0117 0.026
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.025 0.0628 0.2258
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.021 0.0221
Echinococcus multilocularis tar DNA binding protein 0.0132 0.0292 0.0376
Brugia malayi DnaJ domain containing protein 0.0068 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Schistosoma mansoni peroxidasin 0.0114 0.0241 0.0406
Schistosoma mansoni glutamate synthase 0.025 0.0628 0.1059
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.025 0.0628 0.2419
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0075 0.0183
Echinococcus granulosus sex peptide receptor 0.0174 0.0412 0.0531
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0182 0.0434 0.0456
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0048 0.0055 0.0203
Treponema pallidum recombinase A 0.0113 0.024 0.0919
Onchocerca volvulus 0.0271 0.0687 0.2525
Schistosoma mansoni peroxidasin 0.011 0.023 0.0388
Brugia malayi MAP kinase sur-1 0.0103 0.021 0.0468
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0102 0.0105
Loa Loa (eye worm) twinkle helicase 0.0116 0.0247 0.0605
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0113 0.024 0.0688
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0014 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0048 0.0055 0.0053
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0274 0.0285
Brugia malayi hypothetical protein 0.0473 0.126 0.2806
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0148 0.0337 0.0569
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0061 0.009 0.0342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0114 0.0243 0.081
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0206 0.0503 0.1454
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0084 0.0249
Brugia malayi sulfakinin receptor protein 0.0174 0.0412 0.0918
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.025 0.0628 0.14
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0003 0.0009
Trichomonas vaginalis guanylate cyclase, putative 0.0039 0.003 0.0099
Loa Loa (eye worm) hypothetical protein 0.0055 0.0073 0.018
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0405 0.1068 0.4113
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.021 0.0271
Schistosoma mansoni hypothetical protein 0.0174 0.0412 0.0694
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0003 0.0009
Echinococcus multilocularis netrin receptor unc 5 0.0048 0.0054 0.0069
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0057 0.014
Chlamydia trachomatis DNA gyrase subunit B 0.0117 0.0251 0.0962
Echinococcus granulosus uncharacterized sodium dependent transporter 0.007 0.0117 0.0151
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0084 0.0113
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0084 0.0086
Echinococcus granulosus ATP binding cassette sub family G 0.0032 0.0008 0.0011
Brugia malayi intermediate filament protein 0.0056 0.0076 0.017
Schistosoma mansoni hypothetical protein 0.0281 0.0714 0.1204
Trypanosoma brucei NADH dehydrogenase 0.025 0.0628 0.0658
Entamoeba histolytica ABC transporter, putative 0.0032 0.0008 0.0132
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.007 0.0117 0.0197
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0943 0.2593 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Schistosoma mansoni cell polarity protein 0.0035 0.0019 0.0032
Trypanosoma cruzi hydrolase-like protein, putative 0.003 0.0003 0.0003
Echinococcus granulosus histone lysine methyltransferase setb 0.0124 0.0271 0.0349
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0015 0.0025
Onchocerca volvulus 0.0057 0.008 0.0285
Schistosoma mansoni 60S ribosomal protein L21 0.0031 0.0006 0.001
Echinococcus granulosus microtubule associated protein 2 0.2121 0.5933 0.7655
Toxoplasma gondii hypothetical protein 0.007 0.0117 0.0346
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0048 0.0055 0.0053
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0048 0.0055 0.0053
Brugia malayi EGF-like domain containing protein 0.0035 0.0019 0.0043
Mycobacterium leprae Probable lipase LipE 0.0035 0.0018 0.0046
Onchocerca volvulus Peroxidasin homolog 0.011 0.023 0.0839
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0018 0.0045
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.007 0.0117 0.0197
Mycobacterium ulcerans dehydrogenase 0.025 0.0628 0.2416
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1243 0.3444 0.3443
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0009 0.0031
Schistosoma mansoni hypothetical protein 0.0044 0.0043 0.0072
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.0346
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.023 0.0572 0.2196
Onchocerca volvulus 0.007 0.0117 0.0421
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0274 0.0462
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.021 0.0354
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0412 0.1086 0.183
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0046 0.0059
Leishmania major mitochondrial DNA topoisomerase II 0.0182 0.0434 0.0454
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0096 0.019 0.0467
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Loa Loa (eye worm) hypothetical protein 0.007 0.0117 0.0286
Onchocerca volvulus 0.007 0.0117 0.0421
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0018 0.0062
Echinococcus multilocularis G-protein coupled receptor, putative 0.0174 0.0412 0.0531
Loa Loa (eye worm) carboxylesterase 0.0057 0.008 0.0196
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Toxoplasma gondii exonuclease III APE 0.0058 0.0084 0.0249
Onchocerca volvulus 0.0054 0.007 0.025
Loa Loa (eye worm) hypothetical protein 0.0336 0.0873 0.2139
Loa Loa (eye worm) hypothetical protein 0.0054 0.007 0.0173
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.025 0.0628 0.0811
Loa Loa (eye worm) TYRA-2 protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) hypothetical protein 0.0119 0.0257 0.0631
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.008 0.0134
Echinococcus multilocularis carboxylesterase 5A 0.0336 0.0873 0.1126
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0048 0.0055 0.0203
Schistosoma mansoni histamine h1 receptor 0.0174 0.0412 0.0694
Giardia lamblia High cysteine protein 0.0035 0.0019 0.0069
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0943 0.2593 0.2591
Brugia malayi putative neuropeptide receptor 0.0174 0.0412 0.0918
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0035 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0098 0.0195 0.0329
Chlamydia trachomatis replicative DNA helicase 0.0405 0.1068 0.4116
Plasmodium falciparum thioredoxin reductase 0.0943 0.2593 0.7788
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.001 0.0013
Loa Loa (eye worm) animal heme peroxidase 0.011 0.023 0.0564
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0003 0.0003
Schistosoma mansoni single-minded 0.0151 0.0346 0.0584
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0045
Plasmodium vivax DNA topoisomerase II, putative 0.0238 0.0594 0.1782
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0174 0.0412 0.0918
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus multilocularis allatostatin A receptor 0.0174 0.0412 0.0531
Loa Loa (eye worm) solute carrier family 6 member 4 0.0412 0.1086 0.266
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0114 0.0243 0.0255
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1151 0.3182 0.3346
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0035 0.0059
Trichomonas vaginalis myo inositol monophosphatase, putative 0.023 0.0572 0.1909
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0173 0.0579
Loa Loa (eye worm) notch protein 0.0035 0.0019 0.0047
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.025 0.0628 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0076 0.0187
Trichomonas vaginalis chromobox protein, putative 0.0082 0.015 0.05
Schistosoma mansoni hypothetical protein 0.0035 0.0019 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0057 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0114 0.0243 0.081
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Toxoplasma gondii FATC domain-containing protein 0.0044 0.0044 0.0127
Onchocerca volvulus 0.0057 0.008 0.0285
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0194 0.025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Echinococcus multilocularis chromobox protein 1 0.0082 0.015 0.0193
Brugia malayi Pre-SET motif family protein 0.0124 0.0271 0.0603
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Onchocerca volvulus Putative cubilin 0.0035 0.0019 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0118 0.0395
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0015 0.0019
Brugia malayi cytochrome P450 0.0048 0.0055 0.0123
Schistosoma mansoni hypothetical protein 0.0035 0.0019 0.0032
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0051 0.0063 0.0237
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0084 0.0188
Schistosoma mansoni glutamate synthase 0.025 0.0628 0.1059
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Loa Loa (eye worm) hypothetical protein 0.1151 0.3182 0.7796
Brugia malayi hypothetical protein 0.0506 0.1354 0.3017
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0014 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.1085 0.2995 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0194 0.025
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.0292 0.0715
Schistosoma mansoni microtubule-associated protein tau 0.2121 0.5933 1
Trypanosoma cruzi trypanothione reductase, putative 0.1203 0.3329 0.3502
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0048 0.0056 0.0209
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0181 0.0431 0.0726
Brugia malayi hypothetical protein 0.0271 0.0687 0.1531
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0173 0.0579
Plasmodium falciparum amino acid transporter, putative 0.007 0.0117 0.0346
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Brugia malayi RNA binding protein 0.0132 0.0292 0.065
Echinococcus multilocularis RUN 0.0118 0.0253 0.0327
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Brugia malayi larval opioid receptor 0.0174 0.0412 0.0918
Echinococcus granulosus glutamate synthase 0.025 0.0628 0.0811
Toxoplasma gondii selenide, water dikinase 0.025 0.0628 0.1884
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0048 0.0055 0.0053
Echinococcus granulosus netrin receptor unc 5 0.0048 0.0054 0.0069
Echinococcus granulosus uncharacterized sodium dependent transporter 0.007 0.0117 0.0151
Echinococcus granulosus biogenic amine 5HT receptor 0.0432 0.1144 0.1477
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2486 0.6969 0.7329
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0075 0.0166
Plasmodium vivax ataxin-2 like protein, putative 0.0081 0.0149 0.0444
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0048 0.0055 0.0203
Chlamydia trachomatis recombinase RecA 0.0113 0.024 0.0919
Echinococcus multilocularis lipoxygenase domain containing protein 0.0118 0.0253 0.0327
Schistosoma mansoni intermediate filament proteins 0.0056 0.0076 0.0128
Onchocerca volvulus 0.0174 0.0412 0.1509
Schistosoma mansoni loxhd1 0.0118 0.0253 0.0427
Schistosoma mansoni laminin gamma-3 chain 0.0035 0.0019 0.0032
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0693 0.1883 0.4196
Plasmodium falciparum ABC transporter G family member 2 0.0032 0.0008 0.0021
Loa Loa (eye worm) hypothetical protein 0.007 0.0117 0.0286
Echinococcus multilocularis serotonin receptor 0.0432 0.1144 0.1477
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0032 0.0008 0.0006
Echinococcus granulosus fibropellin Ia 0.0035 0.0019 0.0025
Trypanosoma brucei PAB1-binding protein , putative 0.0081 0.0149 0.0154
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1243 0.3444 0.3443
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0049 0.0057 0.0057
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.025 0.0628 0.0661
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0018 0.0016
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0238 0.0594 0.0767
Plasmodium falciparum transporter, putative 0.007 0.0117 0.0346
Mycobacterium tuberculosis Probable oxidoreductase 0.1243 0.3444 0.3443
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0235 0.0585 0.1303
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0084 0.0082
Brugia malayi Animal haem peroxidase family protein 0.011 0.023 0.0513
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.025 0.0628 0.1884
Trichomonas vaginalis DNA topoisomerase II, putative 0.0238 0.0594 0.1985
Schistosoma mansoni biogenic amine (5HT) receptor 0.0432 0.1144 0.1929
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0015 0.005
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.0346
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Loa Loa (eye worm) hypothetical protein 0.0057 0.008 0.0196
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0006 0.001
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0057 0.0096
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0174 0.0412 0.1509
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.025 0.0628 0.0661
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0405 0.1068 0.399
Schistosoma mansoni neuropeptide receptor 0.0174 0.0412 0.0694
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0015 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0044 0.0145
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0943 0.2593 0.4371
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0057 0.0201
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0057 0.0096
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0018 0.0061
Loa Loa (eye worm) RNA binding protein 0.0132 0.0292 0.0715
Onchocerca volvulus 0.0118 0.0253 0.0925
Echinococcus multilocularis abhydrolase domain containing protein 3 0.003 0.0003 0.0003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0039 0.003 0.0099
Brugia malayi Carboxylesterase family protein 0.0057 0.008 0.0178
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.025 0.0628 0.2258
Echinococcus multilocularis neuropeptides capa receptor 0.0174 0.0412 0.0531
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.025 0.0628 0.1884
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0018 0.0024
Onchocerca volvulus Slit protein homolog 0.0035 0.0019 0.0061
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0247 0.0619 0.0799
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0044 0.0044 0.0043
Brugia malayi G-protein coupled receptor 0.0174 0.0412 0.0918
Giardia lamblia PHD finger protein 15 0.0032 0.001 0.0032
Loa Loa (eye worm) TAR-binding protein 0.0132 0.0292 0.0715
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0003 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0057 0.014
Echinococcus multilocularis sodium and chloride dependent glycine 0.007 0.0117 0.0151
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0114 0.0243 0.0253
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0114 0.0243 0.0253
Leishmania major cytochrome p450-like protein 0.0048 0.0055 0.0055
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.008 0.0134
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.023 0.0572 0.0599
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0084 0.0207
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0194 0.025
Loa Loa (eye worm) hypothetical protein 0.0154 0.0354 0.0868
Toxoplasma gondii DNA topoisomerase 2, putative 0.0238 0.0594 0.1782
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0174 0.0412 0.0694
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.0339 0.0755
Toxoplasma gondii hypothetical protein 0.007 0.0117 0.0346
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0274 0.0671
Brugia malayi hypothetical protein 0.007 0.0117 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0132 0.0442
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.025 0.0628 0.154
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0181 0.0431 0.1653
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0096 0.019 0.0246
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.0191 0.0321
Onchocerca volvulus Neurogenic locus notch homolog 0.0036 0.002 0.0065
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0022 0.0028
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0015 0.0037
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0174 0.0412 0.1009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0057 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0063 0.021
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.025 0.0628 0.2416
Echinococcus granulosus sodium channel protein 0.0247 0.0619 0.0799
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Echinococcus granulosus cytochrome P450 2K1 0.0048 0.0055 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0194 0.0326
Brugia malayi nuclear hormone receptor 0.0049 0.0057 0.0127
Brugia malayi Animal haem peroxidase family protein 0.011 0.023 0.0513
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0095 0.0188 0.0195
Loa Loa (eye worm) hypothetical protein 0.0057 0.008 0.0196
Schistosoma mansoni hypothetical protein 0.0068 0.011 0.0186
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0048 0.0055 0.0203
Trypanosoma cruzi hydrolase-like protein 0.003 0.0003 0.0003
Onchocerca volvulus Glucosylceramidase homolog 0.0712 0.1937 0.7132
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus multilocularis neurogenic locus notch protein 0.0035 0.0019 0.0025
Mycobacterium ulcerans ferredoxin reductase 0.025 0.0628 0.2416
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0048 0.0055 0.0053
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0174 0.0412 0.0531
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0076 0.017
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0057 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.075 0.2046 0.6831
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0225 0.0237
Schistosoma mansoni inositol monophosphatase 0.023 0.0572 0.0963
Leishmania major phosphatidylinositol 3-kinase, putative 0.0051 0.0063 0.0064
Plasmodium vivax alpha/beta hydrolase, putative 0.003 0.0003 0.0003
Plasmodium vivax amine transporter, putative 0.007 0.0117 0.0346
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0114 0.0243 0.0313
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0225 0.3587
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0057 0.008 0.0266
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0034 0.0015 0.0019
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0015 0.0025
Schistosoma mansoni hypothetical protein 0.0722 0.1967 0.3316
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0018 0.0031
Echinococcus granulosus g protein coupled receptor 0.0174 0.0412 0.0531
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.025 0.0628 0.1818
Trypanosoma brucei protein kinase, putative 0.0103 0.021 0.0218
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.021 0.0701
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Plasmodium falciparum DNA gyrase subunit A 0.0048 0.0056 0.0163
Brugia malayi Cytochrome P450 family protein 0.0058 0.0082 0.0183
Trypanosoma brucei cytochrome P450, putative 0.0058 0.0082 0.0084
Trypanosoma cruzi target of rapamycin kinase 3 0.0095 0.0188 0.0197
Brugia malayi beta-lactamase 0.0035 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Echinococcus granulosus neuropeptides capa receptor 0.0174 0.0412 0.0531
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.008 0.0077
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0161 0.0376 0.0922
Loa Loa (eye worm) animal heme peroxidase 0.011 0.023 0.0564
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0015 0.0025
Brugia malayi hydrolase, alpha/beta fold family protein 0.003 0.0003 0.0006
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0943 0.2593 0.7788
Schistosoma mansoni hypothetical protein 0.0174 0.0412 0.0694
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0018 0.0062
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.023 0.0572 0.0601
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0345 0.0897 0.1158
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.025 0.0628 0.0811
Brugia malayi putative neuropeptide receptor NPR1 0.0174 0.0412 0.0918
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0018 0.0017
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0057 0.0127
Loa Loa (eye worm) hypothetical protein 0.0044 0.0044 0.0108
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.003 0.0003 0.0003
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.025 0.0628 0.2416
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0107 0.0262
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0943 0.2593 0.2727
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0174 0.0412 0.0531
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0075 0.0166
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.055 0.148 0.1478
Plasmodium falciparum glutathione reductase 0.0943 0.2593 0.7788
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0187 0.0626
Loa Loa (eye worm) hypothetical protein 0.0051 0.0063 0.0155
Loa Loa (eye worm) jmjC domain-containing protein 0.0098 0.0195 0.0478
Trichomonas vaginalis glucosylceramidase, putative 0.0712 0.1937 0.6468
Echinococcus multilocularis Ankyrin 0.0044 0.0044 0.0057
Loa Loa (eye worm) G-protein coupled receptor 0.0174 0.0412 0.1009
Schistosoma mansoni adenoreceptor 0.0174 0.0412 0.0694
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0015 0.0019
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3263 0.9171 0.9171
Schistosoma mansoni neuropeptide F-like receptor 0.0174 0.0412 0.0694
Leishmania major hypothetical protein, conserved 0.0072 0.0122 0.0126
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.007 0.0119
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0194 0.025
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0015 0.0019
Brugia malayi Alpha/beta hydrolase 0.003 0.0003 0.0006
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0182 0.0434 0.0456
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0194 0.0326
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.025 0.0628 0.0626
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0001 0.0005
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.025 0.0628 0.2258
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.007 0.0117 0.0197
Onchocerca volvulus Dual oxidase homolog 0.0187 0.045 0.165
Brugia malayi hypothetical protein 0.0253 0.0636 0.1417
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0102 0.0228
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.025 0.0628 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0253 0.0621
Schistosoma mansoni chromobox protein 0.0082 0.015 0.0252
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0014 0.0036
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0003 0.0009
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0051 0.0063 0.0066
Echinococcus multilocularis conserved hypothetical protein 0.2156 0.6034 0.7785
Loa Loa (eye worm) serotonin transporter b 0.0412 0.1086 0.266
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0052 0.0065 0.0065
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0048 0.0055 0.0053
Brugia malayi bZIP transcription factor family protein 0.0345 0.0897 0.1999
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0014 0.0012
Plasmodium falciparum acid cluster protein 33 homologue, putative 0.003 0.0003 0.0003
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0035 0.0019 0.0032
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0048 0.0055 0.0203
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0225 0.0234
Echinococcus granulosus orexin receptor type 2 0.0174 0.0412 0.0531
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Schistosoma mansoni rab6-interacting 0.0118 0.0253 0.0427
Onchocerca volvulus 0.0174 0.0412 0.1509
Mycobacterium leprae Conserved hypothetical protein 0.0048 0.0055 0.0153
Entamoeba histolytica hypothetical protein 0.0044 0.0044 0.0693
Brugia malayi hypothetical protein 0.0057 0.008 0.0178
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0174 0.0412 0.0694
Brugia malayi hypothetical protein 0.0052 0.0067 0.015
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.021 0.0701
Schistosoma mansoni amine GPCR 0.0174 0.0412 0.0694
Plasmodium falciparum alpha/beta hydrolase, putative 0.003 0.0003 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0044 0.0043 0.0105
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.025 0.0628 0.2416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0063 0.021
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.025 0.0628 0.0626
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0018 0.0016
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0048 0.0055 0.0058
Echinococcus multilocularis lysine specific demethylase 5A 0.0098 0.0195 0.0252
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0114 0.0243 0.0313
Onchocerca volvulus 0.0174 0.0412 0.1509
Schistosoma mansoni opsin-like receptor 0.0174 0.0412 0.0694
Mycobacterium ulcerans DNA gyrase subunit A 0.0048 0.0056 0.0205
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0072 0.0122 0.0157
Brugia malayi isocitrate dehydrogenase 0.0034 0.0014 0.003
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0114 0.0243 0.3861
Echinococcus granulosus sulfide:quinone oxidoreductase 0.025 0.0628 0.0811
Schistosoma mansoni hypothetical protein 0.0174 0.0412 0.0694
Brugia malayi Carboxylesterase family protein 0.0057 0.008 0.0178
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0123 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0063 0.0211
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0134 0.0446
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0039 0.003 0.0029
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0032 0.0008 0.0022
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0051 0.0063 0.0064
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0225 0.086
Echinococcus multilocularis fmrfamide receptor 0.0174 0.0412 0.0531
Echinococcus multilocularis Protein lozenge 0.0059 0.0087 0.0112
Schistosoma mansoni slit 0.0035 0.0019 0.0032
Echinococcus multilocularis neuropeptide receptor 0.0174 0.0412 0.0531
Echinococcus granulosus geminin 0.0722 0.1967 0.2538
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0271 0.0349
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0174 0.0412 0.0531
Echinococcus granulosus tar DNA binding protein 0.0132 0.0292 0.0376
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0018 0.0024
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0238 0.0594 0.1324
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0057 0.0096
Plasmodium vivax ferrodoxin reductase, putative 0.025 0.0628 0.1884
Schistosoma mansoni inositol monophosphatase 0.023 0.0572 0.0963
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.007 0.0117 0.0197
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.008 0.0134
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0001 0.0005
Echinococcus multilocularis neurogenic locus notch protein 0.0035 0.0019 0.0025
Schistosoma mansoni sodium-dependent amino acid transporter 0.007 0.0117 0.0197
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0057 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0057 0.014
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.001 0.0025
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.025 0.0628 0.0658
Schistosoma mansoni jumonji/arid domain-containing protein 0.0098 0.0195 0.0329
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.021 0.0271
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0943 0.2593 0.7788
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0044 0.0043 0.0055
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0274 0.0462
Brugia malayi Carboxylesterase family protein 0.0336 0.0873 0.1945
Echinococcus multilocularis neuropeptide receptor A26 0.1121 0.3098 0.3997
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2845 0.7987 0.84
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0048 0.0055 0.0053
Leishmania major ferric reductase, putative 0.0036 0.0022 0.002
Loa Loa (eye worm) neuropeptide F receptor 0.0174 0.0412 0.1009
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0225 0.3587
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0057 0.0127
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0048 0.0055 0.0053
Entamoeba histolytica glutamate synthase beta subunit, putative 0.025 0.0628 1
Echinococcus multilocularis fat cadherin tumor suppressor 0.0035 0.0019 0.0025
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0003 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0943 0.2593 0.2727
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0018 0.0062
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0174 0.0412 0.0531
Loa Loa (eye worm) hypothetical protein 0.0336 0.0871 0.2133
Plasmodium vivax DNA gyrase subunit B, putative 0.0061 0.009 0.0267
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Echinococcus granulosus protein jagged 2 0.0035 0.0019 0.0025
Onchocerca volvulus 0.007 0.0117 0.0421
Chlamydia trachomatis DNA gyrase subunit B 0.0061 0.009 0.0342
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.025 0.0628 0.0811
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0188 0.045 0.1104
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0018 0.0019
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0034 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0057 0.0096
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0188 0.045 0.1004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.007 0.0117 0.0197
Schistosoma mansoni aryl hydrocarbon receptor 0.0151 0.0346 0.0584
Schistosoma mansoni ankyrin 23/unc44 0.0044 0.0043 0.0072
Entamoeba histolytica hypothetical protein 0.0077 0.0136 0.2157
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0084 0.032
Trichomonas vaginalis apoptosis inducing factor, putative 0.025 0.0628 0.2098
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0024
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.007 0.0117 0.0151
Echinococcus granulosus g protein coupled receptor 0.0174 0.0412 0.0531
Echinococcus granulosus RUN 0.0118 0.0253 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0057 0.0127
Plasmodium vivax SET domain protein, putative 0.0124 0.0271 0.0809
Onchocerca volvulus 0.0119 0.0257 0.0939
Mycobacterium ulcerans glutamate synthase subunit beta 0.025 0.0628 0.2416
Brugia malayi EGF-like domain containing protein 0.0035 0.0019 0.0043
Brugia malayi PHD-finger family protein 0.0032 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus granulosus Polycystic kidney disease protein 0.0118 0.0253 0.0327
Brugia malayi neuropeptide F receptor 0.0174 0.0412 0.0918
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0057 0.0127
Echinococcus multilocularis lamin 0.0056 0.0076 0.0098
Loa Loa (eye worm) hypothetical protein 0.0118 0.0253 0.0621
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0118 0.0394
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Brugia malayi Peroxidasin 0.0114 0.0241 0.0537
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0174 0.0412 0.0694
Trichomonas vaginalis chromobox protein, putative 0.0082 0.015 0.05
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.012 0.0258 0.0633
Onchocerca volvulus 0.0039 0.003 0.01
Onchocerca volvulus 0.0035 0.0019 0.0061
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1085 0.2995 0.6672
Echinococcus granulosus lysosomal acid lipase:cholesteryl ester 0.003 0.0003 0.0003
Brugia malayi Cytochrome P450 family protein 0.0048 0.0055 0.0123
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.007 0.0117 0.0151
Brugia malayi 6-phosphofructokinase 0.0108 0.0225 0.0502
Echinococcus multilocularis dro:myosuppressin receptor 0.0174 0.0412 0.0531
Schistosoma mansoni opsin-like receptor 0.0174 0.0412 0.0694
Echinococcus multilocularis protein jagged 1 0.0035 0.0019 0.0025
Brugia malayi hypothetical protein 0.0118 0.0253 0.0565
Brugia malayi glutathione reductase 0.1203 0.3329 0.7417
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0174 0.0412 0.0918
Schistosoma mansoni myosin xvIII 0.0174 0.0412 0.0694
Echinococcus granulosus peptide allatostatin:somatostatin 0.0174 0.0412 0.0531
Onchocerca volvulus 0.0056 0.0076 0.0271
Onchocerca volvulus 0.0035 0.0019 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0057 0.014
Loa Loa (eye worm) carboxylesterase 0.0336 0.0873 0.2139
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0118 0.0395
Echinococcus multilocularis neurogenic locus notch protein 4 0.0035 0.0019 0.0025
Echinococcus granulosus para nitrobenzyl esterase 0.0057 0.008 0.0103
Echinococcus multilocularis ATP binding cassette sub family G 0.0032 0.0008 0.0011
Mycobacterium leprae Conserved hypothetical protein 0.1195 0.3308 0.9603
Trichomonas vaginalis disulfide oxidoreductase, putative 0.025 0.0628 0.2098
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0051 0.0063 0.0106
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0412 0.0531
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0063 0.0211
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.025 0.0628 0.2098
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0034 0.0015 0.0019
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0057 0.0074
Echinococcus granulosus lamin dm0 0.0056 0.0076 0.0098
Echinococcus granulosus Ankyrin 0.0044 0.0044 0.0057
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0225 0.038
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Schistosoma mansoni ap endonuclease 0.0058 0.0084 0.0142
Onchocerca volvulus 0.0174 0.0412 0.1509
Loa Loa (eye worm) hypothetical protein 0.0034 0.0016 0.0039
Leishmania major cytochrome p450-like protein 0.0058 0.0082 0.0084
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0174 0.0412 0.0531
Echinococcus multilocularis inositol monophosphatase 1 0.023 0.0572 0.0738
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0181 0.0431 0.1653
Loa Loa (eye worm) cytochrome P450 family protein 0.0089 0.0172 0.042
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0063 0.0154
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0034 0.0015 0.0019
Onchocerca volvulus 0.0174 0.0412 0.1509
Loa Loa (eye worm) hypothetical protein 0.0057 0.008 0.0196
Echinococcus multilocularis fibropellin Ia 0.0035 0.0019 0.0025
Brugia malayi Muscle positioning protein 4 0.0035 0.0019 0.0043
Brugia malayi G protein-coupled receptor F59B2.13 0.0174 0.0412 0.0918
Brugia malayi Doublecortin family protein 0.0118 0.0253 0.0565
Giardia lamblia GTOR 0.0114 0.0243 0.0931
Echinococcus multilocularis lipoxygenase domain containing protein 0.0118 0.0253 0.0327
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0123 0.041
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0045
Schistosoma mansoni sodium/chloride dependent transporter 0.0412 0.1086 0.183
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0014 0.0018
Leishmania major DNA topoisomerase ii 0.0238 0.0594 0.0623
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0271 0.0456
Entamoeba histolytica alpha/beta hydrolase domain protein, putative 0.003 0.0003 0.0041
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0274 0.0271
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.025 0.0628 0.1884
Schistosoma mansoni neuropeptide F-like receptor 0.0174 0.0412 0.0694
Mycobacterium tuberculosis Probable reductase 0.055 0.148 0.1478
Echinococcus multilocularis musashi 0.0056 0.0076 0.0098
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0174 0.0412 0.0918
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.025 0.0628 0.0811
Loa Loa (eye worm) hypothetical protein 0.0055 0.0075 0.0183
Trichomonas vaginalis glutamate synthase, putative 0.025 0.0628 0.2098
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0238 0.0594 0.0623
Loa Loa (eye worm) hypothetical protein 0.0057 0.008 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Trichomonas vaginalis spcc417.12 protein, putative 0.0057 0.008 0.0266
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0057 0.014
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0048 0.0055 0.0053
Schistosoma mansoni sulfide quinone reductase 0.025 0.0628 0.1059
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.001 0.0017
Onchocerca volvulus 0.0035 0.0019 0.0061
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0035 0.0019 0.0043
Brugia malayi Calcium binding EGF domain containing protein 0.0035 0.0019 0.0043
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0039 0.003 0.0031
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0057 0.008 0.0103
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.021 0.0221
Mycobacterium leprae Possible regulatory protein 0.0039 0.003 0.0079
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0866 0.2374 0.5818
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0274 0.1047
Plasmodium falciparum glutathione reductase 0.1203 0.3329 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0174 0.0412 0.0531
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.023 0.0572 0.0601
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Treponema pallidum sodium- and chloride- dependent transporter 0.0412 0.1086 0.4183
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0032 0.0008 0.0022
Echinococcus multilocularis lamin dm0 0.0056 0.0076 0.0098
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0164 0.0384 0.0495
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0114 0.0243 0.0253
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0174 0.0412 0.0918
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0238 0.0594 0.0623
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0044 0.0044 0.0073
Chlamydia trachomatis DNA gyrase subunit A 0.0048 0.0056 0.0209
Echinococcus granulosus abhydrolase domain containing protein 0.003 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0057 0.0079 0.0194
Schistosoma mansoni biogenic amine receptor 0.0174 0.0412 0.0694
Echinococcus granulosus sodium and chloride dependent glycine 0.007 0.0117 0.0151
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0014 0.0018
Schistosoma mansoni biogenic amine (5HT) receptor 0.0174 0.0412 0.0694
Schistosoma mansoni chromobox protein 0.0082 0.015 0.0252
Loa Loa (eye worm) hypothetical protein 0.0412 0.1086 0.266
Echinococcus granulosus tm gpcr rhodopsin 0.2761 0.775 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0057 0.0074
Echinococcus multilocularis abhydrolase domain containing protein 0.003 0.0003 0.0003
Echinococcus granulosus dro:myosuppressin receptor 0.0174 0.0412 0.0531
Plasmodium falciparum epoxide hydrolase 1 0.003 0.0003 0.0003
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0057 0.008 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0048 0.0055 0.0053
Onchocerca volvulus 0.0174 0.0412 0.1509
Trichomonas vaginalis inositol monophosphatase, putative 0.023 0.0572 0.1909
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0001 0.0023
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0174 0.0412 0.0694
Brugia malayi alpha/beta hydrolase 0.003 0.0003 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0035 0.0045
Brugia malayi neuropeptide F receptor 0.0174 0.0412 0.0918
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0412 0.1086 0.2419
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.003 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.025 0.0628 0.0658
Schistosoma mansoni septate junction protein 0.0035 0.0019 0.0032
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0057 0.0096
Treponema pallidum thioredoxin reductase (trxB) 0.025 0.0628 0.2419
Loa Loa (eye worm) hypothetical protein 0.0432 0.1144 0.2804
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Echinococcus granulosus tachykinin peptides receptor 99D 0.0174 0.0412 0.0531
Echinococcus granulosus acetylcholinesterase 0.0336 0.0873 0.1126
Entamoeba histolytica hypothetical protein 0.0077 0.0136 0.2157
Loa Loa (eye worm) hypothetical protein 0.0506 0.1354 0.3319
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0018 0.0062
Brugia malayi Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.026
Mycobacterium tuberculosis Putative ferredoxin reductase 0.055 0.148 0.1478
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.025 0.0628 0.0811
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0045
Brugia malayi Calcium binding EGF domain containing protein 0.0035 0.0019 0.0043
Brugia malayi hypothetical protein 0.0118 0.0253 0.0565
Trichomonas vaginalis glucosylceramidase, putative 0.1085 0.2995 1
Echinococcus multilocularis peregrin 0.0032 0.001 0.0013
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.025 0.0628 0.0661
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0018 0.0031
Echinococcus multilocularis sodium channel protein 0.0247 0.0619 0.0799
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0057 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0118 0.0395
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0014 0.0033
Echinococcus granulosus BC026374 protein S09 family 0.0057 0.008 0.0103
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0051 0.0063 0.0064
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0049 0.0057 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0412 0.0531
Echinococcus granulosus death domain containing protein 0.0044 0.0043 0.0055
Loa Loa (eye worm) hypothetical protein 0.0081 0.0149 0.0365
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0114 0.0243 0.0409
Echinococcus multilocularis neuropeptides capa receptor 0.0174 0.0412 0.0531
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0174 0.0412 0.0531
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0014 0.0018
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0072 0.0122 0.0362
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.021 0.0271
Loa Loa (eye worm) hypothetical protein 0.0057 0.008 0.0196
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0057 0.0127
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.008 0.0077
Echinococcus granulosus neuropeptide receptor 0.0174 0.0412 0.0531
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0072 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0187 0.0626
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0174 0.0412 0.0531
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1151 0.3182 0.7088
Trichomonas vaginalis guanylate cyclase, putative 0.0039 0.003 0.0099
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0194 0.0432
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0412 0.0694
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0048 0.0055 0.0203
Brugia malayi Animal haem peroxidase family protein 0.011 0.023 0.0513
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0048 0.0056 0.0163
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Echinococcus granulosus peregrin 0.0032 0.001 0.0013
Echinococcus multilocularis neuroligin 0.0057 0.008 0.0103
Echinococcus granulosus intermediate filament protein 0.0056 0.0076 0.0098
Brugia malayi hydrolase, alpha/beta fold family protein 0.003 0.0003 0.0006
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.021 0.0221
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0102 0.0132
Schistosoma mansoni hypothetical protein 0.0035 0.0019 0.0032
Loa Loa (eye worm) Notch2 0.0035 0.0019 0.0047
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0032 0.0009 0.0024
Echinococcus granulosus survival motor neuron protein 1 0.0727 0.1979 0.2554
Brugia malayi GCC2 and GCC3 family protein 0.0035 0.0019 0.0043
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0046 0.0059
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.007 0.0117 0.0286
Brugia malayi G-protein coupled receptor 0.0174 0.0412 0.0918
Loa Loa (eye worm) hypothetical protein 0.025 0.0628 0.154
Brugia malayi hypothetical protein 0.0727 0.1979 0.441
Trichomonas vaginalis disulfide oxidoreductase, putative 0.025 0.0628 0.2098
Echinococcus multilocularis jun protein 0.0345 0.0897 0.1158
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.045 0.0759
Echinococcus granulosus chromobox protein 1 0.0082 0.015 0.0193
Schistosoma mansoni sulfide quinone reductase 0.025 0.0628 0.1059
Trichomonas vaginalis glutathione reductase, putative 0.0943 0.2593 0.8659
Loa Loa (eye worm) hypothetical protein 0.0473 0.126 0.3087
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0102 0.0108
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0174 0.0412 0.0531
Loa Loa (eye worm) programmed cell death 8 0.025 0.0628 0.154
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0001 0.0005
Trichomonas vaginalis set domain proteins, putative 0.0986 0.2714 0.9061
Schistosoma mansoni lipoxygenase 0.0242 0.0605 0.102
Loa Loa (eye worm) thioredoxin reductase 0.1203 0.3329 0.8158
Giardia lamblia Thioredoxin reductase 0.025 0.0628 0.2419
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0057 0.0127
Echinococcus multilocularis voltage gated potassium channel 0.0041 0.0035 0.0045
Onchocerca volvulus 0.0174 0.0412 0.1509
Leishmania major protein kinase, putative 0.0051 0.0063 0.0063
Echinococcus multilocularis abhydrolase domain containing 3 0.003 0.0003 0.0003
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0165 0.0388 0.142
Trichomonas vaginalis valacyclovir hydrolase, putative 0.003 0.0003 0.0009
Mycobacterium ulcerans carboxylesterase, LipT 0.0057 0.008 0.0298
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.0072 0.0255
Loa Loa (eye worm) hepatopoietin HPO2 0.0072 0.0122 0.0299
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0096 0.019 0.0424
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0114 0.0243 0.0255
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0057 0.0074
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.3381 0.9508 1
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0113 0.024 0.0725
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Mycobacterium tuberculosis Conserved protein 0.0035 0.0018 0.0016
Onchocerca volvulus 0.0174 0.0412 0.1509
Onchocerca volvulus 0.0412 0.1086 0.3993
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0174 0.0412 0.0531
Echinococcus granulosus 7tm_1 domain containing protein 0.0174 0.0412 0.0531
Toxoplasma gondii LsmAD domain-containing protein 0.0081 0.0149 0.0444
Loa Loa (eye worm) hypothetical protein 0.0057 0.008 0.0196
Schistosoma mansoni tar DNA-binding protein 0.0132 0.0292 0.0492
Trichomonas vaginalis hydrolase, putative 0.003 0.0003 0.0009
Trypanosoma brucei ATP-binding cassette protein, putative 0.0032 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0047
Brugia malayi hypothetical protein 0.0174 0.0412 0.0918
Mycobacterium ulcerans putative regulatory protein 0.0112 0.0235 0.0898
Toxoplasma gondii EGF family domain-containing protein 0.0035 0.0019 0.0053
Onchocerca volvulus 0.0035 0.0019 0.0061
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0102 0.0105
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0345 0.0897 0.1158
Echinococcus multilocularis orexin receptor type 2 0.0174 0.0412 0.0531
Brugia malayi Bromodomain containing protein 0.0032 0.001 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0048 0.0055 0.0053
Brugia malayi Serotonin receptor 0.1611 0.4489 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.055 0.148 0.1478
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0412 0.0531
Loa Loa (eye worm) hypothetical protein 0.011 0.023 0.0564
Leishmania major dihydrolipoamide dehydrogenase, putative 0.3381 0.9508 1
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0057 0.0096
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0082 0.0086
Echinococcus granulosus peroxidasin 0.0114 0.0241 0.0311
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0048 0.0055 0.0203
Echinococcus granulosus hypothetical protein 0.233 0.6527 0.8422
Schistosoma mansoni polycystin 1-related 0.0118 0.0253 0.0427
Plasmodium vivax hypothetical protein, conserved 0.003 0.0003 0.0003
Echinococcus granulosus lipoxygenase domain containing protein 0.0118 0.0253 0.0327
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0174 0.0412 0.1009
Trichomonas vaginalis glucosylceramidase, putative 0.0712 0.1937 0.6468
Loa Loa (eye worm) inositol-1 0.023 0.0572 0.1401
Loa Loa (eye worm) hypothetical protein 0.0473 0.126 0.3087
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.014
Echinococcus multilocularis somatostatin receptor 0.0174 0.0412 0.0531
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.025 0.0628 0.2098
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0032 0.0008 0.0021
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0084 0.0086
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0048 0.0055 0.0058
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0045
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2845 0.7987 0.84
Schistosoma mansoni hypothetical protein 0.0035 0.0019 0.0032
Echinococcus granulosus protein jagged 1 0.0035 0.0019 0.0025
Plasmodium falciparum DNA topoisomerase 2 0.0238 0.0594 0.1782
Leishmania major protein kinase, putative 0.0041 0.0034 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0271 0.0456
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0001 0.0005
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0174 0.0412 0.0531
Entamoeba histolytica thioredoxin reductase, putative 0.025 0.0628 1
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.007 0.0117 0.0151
Loa Loa (eye worm) blistered cuticle protein 3 0.0187 0.045 0.1103
Loa Loa (eye worm) hypothetical protein 0.0057 0.008 0.0196
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0049 0.0057 0.0159
Onchocerca volvulus 0.0174 0.0412 0.1509
Schistosoma mansoni Replicative DNA helicase 0.0405 0.1068 0.18
Schistosoma mansoni hypothetical protein 0.0048 0.0055 0.0093
Brugia malayi Animal haem peroxidase family protein 0.011 0.023 0.0513
Brugia malayi Tachykinin-like peptides receptor 99D 0.0174 0.0412 0.0918
Echinococcus multilocularis neuropeptide Y receptor 0.0174 0.0412 0.0531
Entamoeba histolytica alpha/beta hydrolase fold protein, putative 0.003 0.0003 0.0041
Schistosoma mansoni glutamate synthase 0.025 0.0628 0.1059
Plasmodium falciparum DNA gyrase subunit B 0.0061 0.009 0.0267
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0051 0.0063 0.0066
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0044 0.0043 0.0105
Toxoplasma gondii Erv1 / Alr family protein 0.0072 0.0122 0.0362
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0035 0.0059
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0014 0.0023
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0238 0.0594 0.0767
Onchocerca volvulus 0.0035 0.0018 0.0058
Schistosoma mansoni opsin-like receptor 0.0174 0.0412 0.0694
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0084 0.0249
Plasmodium vivax hypothetical protein, conserved 0.007 0.0117 0.0346
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2486 0.6969 0.7329
Schistosoma mansoni biogenic amine receptor 0.0174 0.0412 0.0694
Echinococcus multilocularis tumor protein p63 0.0366 0.0957 0.1234
Echinococcus multilocularis para nitrobenzyl esterase 0.0057 0.008 0.0103
Loa Loa (eye worm) hypothetical protein 0.0174 0.0412 0.1009
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0225 0.0753
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0057 0.0096
Mycobacterium tuberculosis Carboxylesterase LipT 0.0057 0.008 0.0077

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.062 nM Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation counting ChEMBL. 21395312

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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