Detailed information for compound 1526704

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 325.21 | Formula: C16H9Cl2N2OT3
  • H donors: 0 H acceptors: 1 LogP: 3.85 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)C1=NCC(=O)N(c2c1cc(Cl)cc2)C([3H])([3H])[3H]
  • InChi: 1S/C16H12Cl2N2O/c1-20-14-7-6-12(18)8-13(14)16(19-9-15(20)21)10-2-4-11(17)5-3-10/h2-8H,9H2,1H3/i1T3
  • InChiKey: PUMYFTJOWAJIKF-RLXJOQACSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.059 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.022 0.0752
Loa Loa (eye worm) hypothetical protein 0.0966 1 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0131 0.1223 0.1222
Schistosoma mansoni hypothetical protein 0.0034 0.0203 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0196 0.0668
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0035 0.0214 0.0212
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0165 0.0163
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Echinococcus granulosus metabotropic glutamate receptor 5 0.0023 0.0083 0.0082
Echinococcus granulosus hyperpolarization activated cyclic 0.004 0.0265 0.0263
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0131 0.1223 0.1222
Plasmodium vivax amine transporter, putative 0.0041 0.0276 0.0568
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0246 0.0244
Echinococcus multilocularis epidermal growth factor receptor 0.0151 0.1429 0.1428
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0041 0.0051
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0259 0.0257
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0109 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1633 0.5572
Trichomonas vaginalis mercuric reductase, putative 0.0268 0.2658 0.9071
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0035 0.0212 0.021
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0369 0.0367
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0285 0.0283
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.007 0.0574 0.0572
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2571 0.8774
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0035 0.0214 0.0212
Schistosoma mansoni microtubule-associated protein tau 0.0693 0.7132 0.7132
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0233 0.0795
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0197 0.1911 0.1909
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0071 0.059 0.1446
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0197 0.1911 0.1909
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0369 0.0368
Trypanosoma brucei C-8 sterol isomerase, putative 0.037 0.3732 0.4849
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0243 0.2397 0.2395
Schistosoma mansoni tyrosine kinase 0.0082 0.07 0.0699
Schistosoma mansoni nAChR subunit 0.0035 0.0212 0.021
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0276 0.0274
Echinococcus multilocularis nmda type glutamate receptor 0.0102 0.0917 0.0915
Loa Loa (eye worm) hypothetical protein 0.0083 0.0721 0.0719
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0275
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0186 0.1794 0.1793
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Echinococcus multilocularis glycine receptor subunit beta 0.0035 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Entamoeba histolytica hypothetical protein 0.0023 0.0083 0.0146
Schistosoma mansoni tyrosine kinase 0.0049 0.0357 0.0355
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.293 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.009 0.0171
Schistosoma mansoni voltage-gated potassium channel 0.0073 0.0613 0.0612
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0009 0.0007
Brugia malayi hypothetical protein 0.0023 0.0083 0.0082
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0205 0.0417
Schistosoma mansoni ATP-binding cassette transporter 0.0163 0.1556 0.1554
Schistosoma mansoni growth hormone secretagogue receptor 0.0131 0.1223 0.1222
Schistosoma mansoni neuropeptide receptor 0.0131 0.1223 0.1222
Toxoplasma gondii exonuclease III APE 0.0019 0.0041 0.0068
Onchocerca volvulus 0.0966 1 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0381 0.0379
Echinococcus granulosus calcium activated potassium channel 0.0036 0.0218 0.0217
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0186 0.1794 0.1793
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.1223 0.1222
Trypanosoma cruzi calmodulin 0.0025 0.0101 0.0129
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni amine GPCR 0.063 0.6472 0.6471
Leishmania major extracellular receptor, putative 0.0023 0.0083 0.0106
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0067 0.0085
Brugia malayi sulfakinin receptor protein 0.0131 0.1223 0.1222
Brugia malayi chromobox protein homolog 3 0.0039 0.0255 0.0253
Brugia malayi glutathione reductase 0.0462 0.4703 0.4702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0431
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0233 0.0663
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0042 0.004
Brugia malayi nuclear receptor NHR-88 0.002 0.0056 0.0054
Trichomonas vaginalis glutamate synthase, putative 0.0071 0.059 0.2013
Schistosoma mansoni ap endonuclease 0.0019 0.0041 0.0039
Onchocerca volvulus 0.002 0.0056 0.0043
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0038 0.0242 0.0202
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.005 0.0369 0.0368
Schistosoma mansoni tyrosine kinase 0.0025 0.0104 0.0102
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.009 0.0171
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0071 0.059 0.1237
Echinococcus multilocularis transient receptor potential cation channel 0.0035 0.0214 0.0212
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0131 0.1223 0.1222
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0652 0.137
Onchocerca volvulus 0.0041 0.0276 0.0264
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.054 0.1726
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0082 0.0704 0.1479
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0131 0.1223 0.1222
Brugia malayi AKH receptor 0.0131 0.1223 0.1222
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0032 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0056 0.0054
Onchocerca volvulus 0.0031 0.0166 0.0153
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0071 0.059 0.0588
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0056 0.0054
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0265 0.0904
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0317 0.041
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0041 0.0051
Loa Loa (eye worm) glutathione reductase 0.0462 0.4703 0.4702
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0146 0.0144
Echinococcus granulosus transient receptor potential cation channel 0.0035 0.0214 0.0212
Schistosoma mansoni rab6-interacting 0.004 0.0259 0.0257
Echinococcus multilocularis transfer RNA-Gly 0.0035 0.0214 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0056 0.0054
Plasmodium falciparum glutathione reductase 0.0268 0.2658 0.5643
Schistosoma mansoni biogenic amine (5HT) receptor 0.0376 0.3796 0.3795
Treponema pallidum quinoline 2-oxidoreductase 0.0028 0.0133 0.0318
Echinococcus multilocularis fmrfamide receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.001 0.0008
Echinococcus granulosus shaker cognate 0.0035 0.0214 0.0212
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0056 0.0098
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0071 0.059 0.0588
Schistosoma mansoni amine GPCR 0.0131 0.1223 0.1222
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0233 0.0795
Echinococcus granulosus voltage gated hydrogen channel 1 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Schistosoma mansoni histamine h1 receptor 0.0131 0.1223 0.1222
Echinococcus granulosus metabotropic glutamate receptor 2 0.0023 0.0083 0.0082
Entamoeba histolytica hypothetical protein 0.0023 0.009 0.0167
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.1104 0.1102
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0071 0.059 0.1237
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0016 0.0013 0.0011
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0047 0.0059
Echinococcus granulosus FTZ F1 alpha 0.002 0.0056 0.0054
Echinococcus granulosus sodium channel protein 0.0428 0.434 0.4339
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0381 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0338
Trypanosoma cruzi C-8 sterol isomerase, putative 0.037 0.3732 0.4849
Echinococcus multilocularis tyrosine kinase 0.0025 0.0104 0.0102
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.1223 0.1222
Onchocerca volvulus 0.0035 0.0212 0.0199
Brugia malayi jmjC domain containing protein 0.0096 0.0851 0.085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0641 0.6587 0.856
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0047 0.0059
Plasmodium vivax DNA gyrase subunit A, putative 0.003 0.016 0.0321
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0186 0.1794 0.1793
Loa Loa (eye worm) TYRA-2 protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0071 0.059 0.0588
Loa Loa (eye worm) hypothetical protein 0.0376 0.3796 0.3795
Loa Loa (eye worm) voltage-gated potassium channel 0.0035 0.0214 0.0212
Schistosoma mansoni opsin-like receptor 0.0131 0.1223 0.1222
Schistosoma mansoni glutamate synthase 0.0071 0.059 0.0588
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0035 0.0212 0.021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0249 0.0247
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0035 0.0214 0.0212
Schistosoma mansoni hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) serotonin transporter b 0.0243 0.2397 0.2396
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0071 0.059 0.0588
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0571 0.5846 0.7596
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0025 0.0101 0.01
Echinococcus multilocularis neuropeptide FF receptor 2 0.0131 0.1223 0.1222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0006
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.004 0.0259 0.0258
Leishmania major ferric reductase, putative 0.0034 0.0203 0.0261
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0071 0.059 0.1446
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0174 0.1673 0.571
Mycobacterium ulcerans monoxygenase 0.0071 0.059 0.0551
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Echinococcus multilocularis voltage dependent calcium channel 0.0129 0.1203 0.1201
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni transient receptor potential channel 0.0035 0.0214 0.0212
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0039 0.0249 0.0247
Loa Loa (eye worm) hypothetical protein 0.0428 0.4347 0.4347
Echinococcus granulosus g protein coupled receptor 0.0131 0.1223 0.1222
Plasmodium falciparum thioredoxin reductase 0.0462 0.4703 1
Schistosoma mansoni protein kinase 0.0028 0.0139 0.0137
Loa Loa (eye worm) hypothetical protein 0.0033 0.0185 0.0184
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.059 0.0764
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.054 0.0538
Echinococcus multilocularis glutamate receptor NMDA 0.0079 0.0676 0.0674
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1633 0.5572
Plasmodium vivax DNA gyrase subunit B, putative 0.0082 0.0704 0.1479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.022 0.0752
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0035 0.0212 0.021
Loa Loa (eye worm) melatonin receptor type 1A 0.0131 0.1223 0.1222
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.059 0.2013
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.004 0.0265 0.0263
Schistosoma mansoni amine GPCR 0.0131 0.1223 0.1222
Echinococcus granulosus glutamate receptor 2 0.0116 0.1063 0.1061
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0035 0.0212 0.021
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0035 0.0214 0.0212
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0071 0.059 0.0588
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0131 0.1223 0.1222
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.007 0.0578 0.0576
Schistosoma mansoni hypothetical protein 0.0016 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0381 0.0493
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1633 0.5572
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0044
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.003 0.016 0.0321
Brugia malayi nuclear hormone receptor 0.002 0.0056 0.0054
Echinococcus granulosus tachykinin peptides receptor 99D 0.0131 0.1223 0.1222
Echinococcus granulosus geminin 0.017 0.1633 0.1631
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0174 0.1672 0.167
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0381 0.0493
Echinococcus granulosus snurportin 1 0.0372 0.3753 0.3752
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0035 0.0214 0.0212
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0016 0.0053
Echinococcus granulosus microtubule associated protein 2 0.0693 0.7132 0.7132
Echinococcus multilocularis transient receptor potential cation channel 0.0035 0.0214 0.0212
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0287 0.0978
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0056 0.0054
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0165 0.0163
Mycobacterium ulcerans hypothetical protein 0.0071 0.059 0.0551
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0047 0.0046
Trypanosoma cruzi calmodulin, putative 0.0025 0.0101 0.0129
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.0301 0.0299
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0082 0.0704 0.2531
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0016 0.0053
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0071 0.059 0.0588
Schistosoma mansoni sodium/chloride dependent transporter 0.0243 0.2397 0.2395
Brugia malayi calmodulin 0.0025 0.0101 0.01
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0056 0.0054
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0369 0.0367
Schistosoma mansoni sodium-dependent amino acid transporter 0.0041 0.0276 0.0274
Trypanosoma cruzi NADH dehydrogenase, putative 0.0071 0.059 0.0764
Onchocerca volvulus 0.0131 0.1223 0.1212
Brugia malayi hypothetical protein 0.0016 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0255 0.0254
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0381 0.0493
Brugia malayi protein-tyrosine kinase 0.0035 0.0211 0.0209
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Echinococcus multilocularis calmodulin 0.0025 0.0101 0.01
Chlamydia trachomatis DNA gyrase subunit B 0.0082 0.0704 0.2391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0337
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0056 0.0054
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0205 0.0264
Schistosoma mansoni glutamate receptor AMPA 0.0163 0.1553 0.1552
Toxoplasma gondii calmodulin, putative 0.0025 0.0101 0.0196
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0035 0.0212 0.021
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0035 0.0212 0.021
Brugia malayi PHD-finger family protein 0.0029 0.0151 0.0149
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0428 0.4347 0.4346
Echinococcus granulosus peregrin 0.0029 0.0151 0.0149
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.001 0.001
Trichomonas vaginalis apoptosis inducing factor, putative 0.0071 0.059 0.2013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0006
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0035 0.0214 0.0212
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0268 0.2658 0.5643
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0268 0.2658 0.5643
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0246 0.0244
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0317 0.041
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0035 0.0214 0.0212
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0317 0.041
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0129 0.1203 0.1201
Echinococcus multilocularis tyrosine protein kinase Srms 0.0035 0.0211 0.0209
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0165 0.0163
Leishmania major DNA topoisomerase ii 0.0133 0.124 0.1609
Echinococcus granulosus peptide allatostatin:somatostatin 0.0131 0.1223 0.1222
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0071 0.059 0.0588
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0016 0.0013 0.0011
Brugia malayi Cyclic-nucleotide gated cation channel 0.004 0.0265 0.0263
Plasmodium falciparum amino acid transporter, putative 0.0041 0.0276 0.0568
Schistosoma mansoni calmodulin 0.0025 0.0101 0.01
Loa Loa (eye worm) voltage-gated potassium channel 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Echinococcus multilocularis hyperpolarization activated cyclic 0.004 0.0265 0.0263
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2571 0.8774
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0056 0.0054
Echinococcus multilocularis chromobox protein 1 0.007 0.0579 0.0577
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0041 0.0039
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0039 0.0249 0.0247
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.009 0.0167
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0092 0.0805 0.1044
Echinococcus multilocularis transient receptor potential cation channel 0.0035 0.0214 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0124 0.0422
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0259 0.0532
Schistosoma mansoni hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0851 0.085
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0276 0.0274
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0249 0.0247
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0035 0.0212 0.021
Echinococcus multilocularis lamin 0.0033 0.0185 0.0183
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0129 0.1203 0.1201
Brugia malayi Isocitrate dehydrogenase 0.0016 0.001 0.0008
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0381 0.0379
Loa Loa (eye worm) hypothetical protein 0.0547 0.5597 0.5596
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0131 0.1223 0.1222
Leishmania major hypothetical protein, conserved 0.0071 0.059 0.0764
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.1223 0.1222
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.001
Echinococcus granulosus insulin receptor 0.0049 0.0357 0.0355
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0071 0.059 0.1237
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0571 0.5846 0.7596
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0035 0.0212 0.021
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0016 0.0013 0.0011
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0056 0.0054
Giardia lamblia Thioredoxin reductase 0.0071 0.059 0.1899
Treponema pallidum oxidoreductase 0.0071 0.059 0.1899
Schistosoma mansoni hypothetical protein 0.017 0.1633 0.1631
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0317 0.0316
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0129 0.1203 0.1201
Brugia malayi follicle stimulating hormone receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0237 0.2341 0.2339
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni nAChR subunit 0.0035 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0443 0.0442
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0056 0.0054
Echinococcus multilocularis neuropeptide receptor A26 0.0593 0.6083 0.6082
Brugia malayi Pre-SET motif family protein 0.0031 0.0165 0.0163
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0131 0.1223 0.1222
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0071 0.059 0.1446
Onchocerca volvulus 0.0239 0.2354 0.2344
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Loa Loa (eye worm) programmed cell death 8 0.0071 0.059 0.0588
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0276 0.0274
Loa Loa (eye worm) hypothetical protein 0.0031 0.0165 0.0163
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.014 0.1319 0.1318
Brugia malayi Augmenter of liver regeneration 0.0034 0.0205 0.0203
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Schistosoma mansoni voltage-gated potassium channel 0.0073 0.0613 0.0612
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0214 0.0435
Echinococcus granulosus calmodulin 0.0025 0.0101 0.01
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0175 0.1683 0.3566
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0275
Plasmodium falciparum phd finger protein, putative 0.0029 0.0151 0.0301
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0036 0.0226 0.0462
Mycobacterium ulcerans DNA gyrase subunit A 0.003 0.016 0.0119
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.0301 0.0299
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0317 0.0956
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Onchocerca volvulus 0.0966 1 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0035 0.0212 0.021
Echinococcus granulosus G protein coupled receptor 139 0.0131 0.1223 0.1222
Toxoplasma gondii hypothetical protein 0.0035 0.0214 0.0435
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0035 0.0214 0.0212
Schistosoma mansoni tyrosine kinase 0.0082 0.07 0.0699
Brugia malayi DNA topoisomerase II, alpha isozyme 0.014 0.1319 0.1318
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0129 0.1203 0.1201
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0035 0.0212 0.021
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0041 0.0051
Echinococcus multilocularis musashi 0.0033 0.0185 0.0183
Echinococcus granulosus tyrosine protein kinase Blk 0.0035 0.0211 0.0209
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0056 0.0054
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0271 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0317 0.1083
Onchocerca volvulus Alhambra homolog 0.0029 0.0151 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0338
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.0028
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0652 0.1615
Echinococcus multilocularis dro:myosuppressin receptor 0.0131 0.1223 0.1222
Schistosoma mansoni cpg binding protein 0.0029 0.0146 0.0144
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Echinococcus granulosus cpg binding protein 0.003 0.0163 0.0161
Giardia lamblia DNA topoisomerase II 0.0133 0.1242 0.4157
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0131 0.1223 0.1222
Brugia malayi Blistered cuticle protein 3 0.0073 0.061 0.0608
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.054 0.0699
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0035 0.0214 0.0212
Echinococcus multilocularis microtubule associated protein 2 0.0693 0.7132 0.7132
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Loa Loa (eye worm) ion channel NompC 0.0035 0.0214 0.0212
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.001 0.0008
Plasmodium falciparum thioredoxin reductase 0.0268 0.2658 0.5643
Mycobacterium ulcerans DNA gyrase subunit B 0.0082 0.0704 0.0665
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0035 0.0212 0.021
Echinococcus multilocularis g protein coupled receptor 0.0131 0.1223 0.1222
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.003 0.0028
Echinococcus granulosus g protein coupled receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0108 0.0974 0.0972
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0275
Trypanosoma brucei calmodulin 0.0025 0.0101 0.0129
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0082 0.0706 0.0667
Loa Loa (eye worm) glutamate receptor 0.0023 0.0083 0.0082
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.2571 0.2569
Echinococcus granulosus calmodulin 0.0025 0.0101 0.01
Echinococcus multilocularis insulin receptor 0.0049 0.0357 0.0355
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0028 0.0139 0.0126
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.004 0.0265 0.0263
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0035 0.0214 0.0212
Schistosoma mansoni loxhd1 0.004 0.0259 0.0257
Onchocerca volvulus 0.0035 0.0212 0.0199
Echinococcus granulosus calmodulin 0.0025 0.0101 0.01
Schistosoma mansoni hypothetical protein 0.0016 0.0009 0.0007
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0276 0.0274
Onchocerca volvulus 0.0035 0.0214 0.0201
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0233 0.03
Leishmania major C-8 sterol isomerase-like protein 0.037 0.3732 0.4849
Treponema pallidum hypothetical protein 0.0023 0.0088 0.0161
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0092 0.0805 0.1044
Brugia malayi Pre-SET motif family protein 0.021 0.2048 0.2046
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0192 0.0389
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0046 0.0328 0.112
Trypanosoma brucei trypanothione reductase 0.0462 0.4703 0.611
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0041 0.0276 0.0726
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0233 0.0732
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0071 0.059 0.1446
Echinococcus multilocularis glutamate receptor 2 0.0116 0.1063 0.1061
Loa Loa (eye worm) hypothetical protein 0.0031 0.0166 0.0164
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0056 0.0054
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0139 0.0137
Toxoplasma gondii thioredoxin reductase 0.0462 0.4703 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0317 0.041
Schistosoma mansoni hypothetical protein 0.0016 0.0009 0.0007
Onchocerca volvulus 0.0966 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0275
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0443 0.0442
Onchocerca volvulus 0.0035 0.0212 0.0199
Brugia malayi intermediate filament protein 0.0033 0.0185 0.0183
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0041 0.0068
Schistosoma mansoni tyrosine kinase 0.008 0.068 0.0678
Echinococcus multilocularis GPCR, family 2 0.0016 0.0009 0.0007
Schistosoma mansoni nAChR subunit 0.0035 0.0212 0.021
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0268 0.2658 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0139 0.0137
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0023 0.0083 0.0082
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0372 0.3751 0.7973
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0216 0.0214
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0048 0.0046
Schistosoma mansoni sulfide quinone reductase 0.0071 0.059 0.0588
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0035 0.0214 0.0201
Leishmania major importin beta-1 subunit, putative 0.0028 0.014 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0338
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0032 0.0109
Toxoplasma gondii transporter, cation channel family protein 0.0053 0.04 0.0833
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0205 0.0264
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0212 0.021
Echinococcus multilocularis peregrin 0.0029 0.0151 0.0149
Leishmania major calmodulin, putative 0.0025 0.0101 0.0129
Onchocerca volvulus Neuropeptide F receptor homolog 0.0131 0.1223 0.1212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0196 0.0668
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1633 0.5572
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0158 0.15 0.1947
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0109 0.0212
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.1223 0.1222
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0038 0.0242 0.0496
Schistosoma mansoni sulfide quinone reductase 0.0071 0.059 0.0588
Mycobacterium ulcerans glutamate synthase subunit beta 0.0071 0.059 0.0551
Mycobacterium leprae conserved hypothetical protein 0.0023 0.009 0.0092
Echinococcus granulosus voltage gated potassium channel 0.0044 0.0301 0.0299
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1633 0.5572
Toxoplasma gondii hypothetical protein 0.0041 0.0276 0.0568
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0095 0.084 0.0829
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Echinococcus multilocularis NMDA receptor 0.007 0.0574 0.0572
Schistosoma mansoni hypothetical protein 0.004 0.0259 0.0257
Entamoeba histolytica hypothetical protein 0.0028 0.014 0.034
Brugia malayi hypothetical protein 0.0016 0.0013 0.0011
Loa Loa (eye worm) GABA receptor subunit 0.0019 0.0042 0.004
Echinococcus granulosus importin subunit beta 1 0.0035 0.0209 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0255 0.0871
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0059 0.0461 0.0421
Brugia malayi Heterochromatin protein 1 0.007 0.0579 0.0577
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1633 0.5572
Echinococcus multilocularis G-protein coupled receptor, putative 0.0131 0.1223 0.1222
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0221 0.0284
Brugia malayi Dopamine receptor protein 1 0.0547 0.5597 0.5596
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0249 0.0247
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0133 0.124 0.1609
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0047 0.0046
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0023 0.0083 0.0082
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0233 0.0231
Brugia malayi SRC-1 0.0039 0.0249 0.0247
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0035 0.0214 0.0212
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.004 0.0265 0.0263
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0151 0.0149
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0209 0.0269
Plasmodium falciparum DNA gyrase subunit A 0.003 0.016 0.0321
Leishmania major NADH dehydrogenase, putative 0.0071 0.059 0.0764
Onchocerca volvulus 0.0131 0.1223 0.1212
Loa Loa (eye worm) hypothetical protein 0.0189 0.1831 0.1829
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0071 0.059 0.0551
Loa Loa (eye worm) hypothetical protein 0.0129 0.1203 0.1202
Brugia malayi Glutamate receptor 2 precursor 0.0163 0.1553 0.1552
Brugia malayi RNA, U transporter 1 0.0099 0.0884 0.0883
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2571 0.8774
Brugia malayi Glutamate receptor 1 precursor 0.0163 0.1553 0.1552
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.1351 0.3505
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0571 0.5846 0.7596
Loa Loa (eye worm) hypothetical protein 0.004 0.0259 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0135 0.046
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0186 0.1794 0.1793
Loa Loa (eye worm) hypothetical protein 0.0547 0.5597 0.5596
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0038 0.0242 0.0696
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.003 0.016 0.0412
Onchocerca volvulus 0.0048 0.0352 0.034
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0034 0.0203 0.0261
Loa Loa (eye worm) hypothetical protein 0.0376 0.3796 0.3795
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0056 0.0054
Echinococcus multilocularis g protein coupled receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0109 0.0139
Trichomonas vaginalis glutathione reductase, putative 0.0268 0.2658 0.9071
Brugia malayi Guanylyl cyclase protein 23 0.0028 0.0139 0.0137
Plasmodium vivax thioredoxin reductase, putative 0.0462 0.4703 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Brugia malayi Cation transporter family protein 0.0035 0.0212 0.021
Schistosoma mansoni chromobox protein 0.007 0.0579 0.0577
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0641 0.6587 0.856
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0035 0.0212 0.021
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0479 0.0477
Echinococcus granulosus voltage gated potassium channel 0.0035 0.0214 0.0212
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0035 0.0212 0.021
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0233 0.0795
Echinococcus multilocularis translocator protein 0.0966 1 1
Brugia malayi CXXC zinc finger family protein 0.0029 0.0146 0.0144
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.1223 0.1222
Brugia malayi hypothetical protein 0.0016 0.0013 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0032 0.0109
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0462 0.4703 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0268 0.2658 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Brugia malayi Cation transporter family protein 0.0035 0.0212 0.021
Brugia malayi hypothetical protein 0.004 0.0259 0.0257
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0071 0.059 0.2013
Echinococcus multilocularis allatostatin A receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.1223 0.1222
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0071 0.059 0.1237
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.009 0.0185
Schistosoma mansoni cpg binding protein 0.003 0.0163 0.0161
Loa Loa (eye worm) hypothetical protein 0.0034 0.0203 0.0201
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0196 0.0397
Schistosoma mansoni lamin 0.0033 0.0185 0.0183
Echinococcus granulosus g-protein coupled receptor 0.0131 0.1223 0.1222
Echinococcus granulosus orexin receptor type 2 0.0131 0.1223 0.1222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.022 0.0752
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0039 0.025 0.0248
Schistosoma mansoni neuropeptide receptor 0.0131 0.1223 0.1222
Schistosoma mansoni survival motor neuron protein 0.0048 0.0352 0.035
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.016 0.0275
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Echinococcus granulosus serotonin transporter 0.0243 0.2397 0.2395
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0056 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0032 0.0109
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Leishmania major hypothetical protein, conserved 0.0071 0.059 0.0764
Treponema pallidum fructose-bisphosphate aldolase 0.0294 0.293 1
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0035 0.0212 0.021
Schistosoma mansoni lipoxygenase 0.0174 0.1672 0.167
Schistosoma mansoni disulfide oxidoreductase 0.0071 0.059 0.0588
Echinococcus multilocularis receptor type guanylyl cyclase 0.0028 0.0139 0.0137
Loa Loa (eye worm) norepinephrine transporter 0.0243 0.2397 0.2396
Onchocerca volvulus 0.0075 0.0631 0.0619
Echinococcus multilocularis two pore calcium channel protein 2 0.0035 0.0214 0.0212
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0071 0.059 0.2097
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0071 0.059 0.1237
Echinococcus granulosus 7tm_1 domain containing protein 0.0131 0.1223 0.1222
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0233 0.03
Schistosoma mansoni nAChR subunit 0.0035 0.0212 0.021
Echinococcus granulosus tm gpcr rhodopsin 0.0963 0.9971 0.9971
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0023 0.0083 0.0082
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0641 0.6587 0.856
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0019 0.0042 0.004
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0059 0.0461 0.0961
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Echinococcus multilocularis glutamate synthase 0.0071 0.059 0.0588
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0044 0.0301 0.0299
Schistosoma mansoni tyrosine kinase 0.0025 0.0104 0.0102
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0203 0.0261
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0071 0.059 0.2013
Echinococcus multilocularis potassium voltage gated channel protein 0.0035 0.0214 0.0212
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0268 0.2658 0.3452
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0158 0.15 0.1947
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0071 0.059 0.0764
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.004 0.0265 0.0263
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0317 0.0316
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Brugia malayi hypothetical protein 0.0016 0.0013 0.0011
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0216 0.0214
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0035 0.0214 0.0201
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0205 0.0417
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0009 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0747 0.7695 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0265 0.0904
Schistosoma mansoni amine GPCR 0.0131 0.1223 0.1222
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0131 0.1223 0.1222
Schistosoma mansoni lipoxygenase 0.0103 0.0922 0.092
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0056 0.0054
Brugia malayi Inositol-1 0.0037 0.0233 0.0231
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0129 0.1203 0.1201
Onchocerca volvulus 0.0078 0.0666 0.0654
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0056 0.0054
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0233 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0135 0.046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0056 0.0054
Echinococcus granulosus neuropeptide receptor A26 0.0593 0.6083 0.6082
Echinococcus granulosus biogenic amine 5HT receptor 0.0376 0.3796 0.3795
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0008 0.0006
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0016 0.0013 0.0011
Echinococcus multilocularis voltage gated potassium channel 0.0035 0.0214 0.0212
Brugia malayi Adenylyl cyclase protein 0.0078 0.0666 0.0664
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0381 0.0493
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0056 0.0054
Schistosoma mansoni voltage-gated cation channel 0.0129 0.1203 0.1201
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0372 0.3751 0.7973
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0281 0.0279
Echinococcus granulosus somatostatin receptor 0.0131 0.1223 0.1222
Onchocerca volvulus 0.005 0.0365 0.0353
Loa Loa (eye worm) TK protein kinase 0.0031 0.0171 0.0169
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0129 0.1203 0.1201
Brugia malayi hypothetical protein 0.0066 0.0539 0.0537
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0035 0.0212 0.021
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0052 0.0385 0.0345
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.004 0.0265 0.0263
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0046 0.0328 0.112
Leishmania major hypothetical protein, conserved 0.0071 0.059 0.0764
Loa Loa (eye worm) hypothetical protein 0.0077 0.0652 0.0651
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Brugia malayi hypothetical protein 0.004 0.0259 0.0257
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0275
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0056 0.0054
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0035 0.0212 0.021
Echinococcus granulosus nAChR subunit 0.0019 0.0042 0.004
Onchocerca volvulus 0.0131 0.1223 0.1212
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.016 0.0275
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0131 0.1223 0.1222
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0035 0.0214 0.0212
Brugia malayi Serotonin receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) ACC-1 protein 0.0035 0.0212 0.021
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0175 0.1683 0.4404
Echinococcus granulosus RUN 0.004 0.0259 0.0257
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.059 0.2013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0082 0.0704 0.1479
Echinococcus multilocularis RUN 0.004 0.0259 0.0257
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0049 0.0357 0.0355
Giardia lamblia PHD finger protein 15 0.0029 0.0151 0.0378
Plasmodium vivax calmodulin, putative 0.0025 0.0101 0.0196
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0151 0.0149
Schistosoma mansoni ryanodine receptor related 0.0035 0.0214 0.0212
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0131 0.1223 0.1222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0196 0.0668
Brugia malayi G-protein coupled receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) TK/EGFR protein kinase 0.0151 0.1429 0.1428
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.1351 0.2858
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0071 0.059 0.1237
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.005 0.0371 0.0369
Mycobacterium ulcerans hypothetical protein 0.0028 0.014 0.0099
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0317 0.0316
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0071 0.059 0.0588
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0035 0.0214 0.0212
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0035 0.0212 0.021
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0023 0.0083 0.0082
Plasmodium falciparum calmodulin 0.0025 0.0101 0.0196
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.054 0.0538
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0428 0.4347 0.4347
Trypanosoma brucei DNA topoisomerase ii 0.0158 0.15 0.1947
Schistosoma mansoni metabotropic glutamate receptor 0.0023 0.0083 0.0082
Loa Loa (eye worm) calcium channel 0.0129 0.1203 0.1202
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0071 0.059 0.1237
Echinococcus granulosus cyclic nucleotide gated cation channel 0.004 0.0265 0.0263
Entamoeba histolytica thioredoxin reductase, putative 0.0071 0.059 0.1899
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0317 0.041
Echinococcus multilocularis ryanodine receptor 44f 0.0035 0.0214 0.0212
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0131 0.1223 0.1212
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0365 0.0363
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0035 0.0212 0.021
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0071 0.059 0.1237
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0233 0.0231
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0131 0.1223 0.1222
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0071 0.059 0.0551
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0009 0.0008
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0071 0.059 0.1237
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0047 0.0046
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0071 0.059 0.0588
Onchocerca volvulus 0.0131 0.1223 0.1212
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Trichomonas vaginalis importin beta-1, putative 0.0028 0.014 0.0477
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0205 0.0203
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0049 0.0357 0.0355
Loa Loa (eye worm) hypothetical protein 0.037 0.3732 0.3731
Echinococcus multilocularis sodium leak channel non selective protein 0.0035 0.0214 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0196 0.0668
Onchocerca volvulus 0.0029 0.0146 0.0133
Loa Loa (eye worm) acetylcholine receptor protein 0.0016 0.0013 0.0011
Schistosoma mansoni glutamate synthase 0.0071 0.059 0.0588
Echinococcus multilocularis sex peptide receptor 0.0131 0.1223 0.1222
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0212 0.021
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0035 0.0212 0.021
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.1104 0.1102
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0175 0.1683 0.3566
Schistosoma mansoni cpg binding protein 0.003 0.0163 0.0161
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0035 0.0212 0.021
Brugia malayi cation channel family protein 0.0035 0.0214 0.0212
Echinococcus multilocularis epidermal growth factor receptor 0.0082 0.07 0.0699
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0071 0.059 0.1237
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Brugia malayi Furin-like cysteine rich region family protein 0.0151 0.1429 0.1428
Echinococcus multilocularis calmodulin 0.0025 0.0101 0.01
Brugia malayi ecdysteroid receptor 0.002 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus transient receptor potential cation channel 0.0035 0.0214 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.1223 0.1222
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0035 0.0212 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0431
Echinococcus granulosus dro:myosuppressin receptor 0.0131 0.1223 0.1222
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0268 0.2658 0.3452
Onchocerca volvulus 0.0041 0.0276 0.0264
Loa Loa (eye worm) ACC-1 protein 0.0035 0.0212 0.021
Echinococcus multilocularis serotonin transporter 0.0243 0.2397 0.2395
Loa Loa (eye worm) glutamate receptor 2 0.0163 0.1553 0.1552
Onchocerca volvulus Putative nachr subunit 0.0035 0.0212 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0006
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.004 0.0265 0.0263
Brugia malayi hypothetical protein 0.039 0.3944 0.3943
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Schistosoma mansoni intermediate filament proteins 0.0033 0.0185 0.0183
Echinococcus multilocularis cpg binding protein 0.003 0.0163 0.0161
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0035 0.0212 0.021
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0212 0.021
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0259 0.0532
Entamoeba histolytica DNA topoisomerase II, putative 0.014 0.1319 0.4424
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0175 0.1683 0.3566
Loa Loa (eye worm) hypothetical protein 0.0078 0.0666 0.0664
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0381 0.13
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Echinococcus multilocularis nmda type glutamate receptor 0.0187 0.1807 0.1805
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0131 0.1223 0.1222
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0041 0.0276 0.0274
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus glutamate receptor ionotropic kainate 0.007 0.0574 0.0572
Schistosoma mansoni transient receptor potential channel 0.0036 0.0216 0.0214
Giardia lamblia NADH oxidase lateral transfer candidate 0.0268 0.2658 0.9058
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0016 0.0013 0.0011
Brugia malayi neuropeptide F receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) doublecortin family protein 0.004 0.0259 0.0258
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Onchocerca volvulus 0.0131 0.1223 0.1212
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0652 0.137
Schistosoma mansoni nAChR subunit 0.0016 0.0013 0.0011
Schistosoma mansoni polycystin 1-related 0.004 0.0259 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0056 0.0054
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0216 0.0214
Plasmodium falciparum DNA gyrase subunit B 0.0082 0.0704 0.1479
Entamoeba histolytica hypothetical protein 0.0019 0.0042 0.0001
Mycobacterium ulcerans NADH dehydrogenase 0.0071 0.059 0.0551
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0131 0.1223 0.1222
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0276 0.0274
Trichomonas vaginalis aldehyde oxidase, putative 0.0174 0.1673 0.571
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0032 0.0109
Echinococcus multilocularis two pore calcium channel protein 1 0.0035 0.0214 0.0212
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.001 0.0008
Brugia malayi ERG2 and Sigma1 receptor like protein 0.037 0.3732 0.3731
Echinococcus multilocularis neuropeptide s receptor 0.0593 0.6083 0.6082
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus thioredoxin glutathione reductase 0.0462 0.4703 0.4702
Echinococcus granulosus sodium leak channel non selective protein 0.0035 0.0214 0.0212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Brugia malayi isocitrate dehydrogenase 0.0016 0.001 0.0008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0165 0.033
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0268 0.2658 0.5643
Loa Loa (eye worm) hypothetical protein 0.0966 1 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0035 0.0214 0.0212
Toxoplasma gondii NADPH-glutathione reductase 0.0268 0.2658 0.5643
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.022 0.0752
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0056 0.0054
Onchocerca volvulus 0.0025 0.0101 0.0088
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0078 0.0666 0.0654
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0071 0.059 0.0588
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Echinococcus granulosus voltage dependent calcium channel 0.0129 0.1203 0.1201
Brugia malayi putative neuropeptide receptor NPR1 0.0131 0.1223 0.1222
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0151 0.0301
Brugia malayi RE15519p 0.0131 0.1223 0.1222
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0268 0.2658 0.2657
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0381 0.0379
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0056 0.0054
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0381 0.0493
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Mycobacterium tuberculosis Probable oxidoreductase 0.0372 0.3751 0.7973
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0016 0.0013 0.0011
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0721 0.0719
Echinococcus multilocularis calmodulin 0.0025 0.0101 0.01
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0041 0.0068
Echinococcus granulosus nAChR subunit 0.0035 0.0212 0.021
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0151 0.0301
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Echinococcus granulosus hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni tyrosine kinase 0.008 0.068 0.0678
Schistosoma mansoni neuropeptide f receptor 76f 0.0131 0.1223 0.1222
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0035 0.0212 0.021
Schistosoma mansoni hypothetical protein 0.0029 0.0151 0.0149
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0151 0.0149
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0056 0.0054
Echinococcus granulosus alpha 1A adrenergic receptor 0.0131 0.1223 0.1222
Brugia malayi Tachykinin-like peptides receptor 99D 0.0131 0.1223 0.1222
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0259 0.0257
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Onchocerca volvulus 0.004 0.0259 0.0247
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.059 0.2013
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0016 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.0071 0.059 0.0588
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Echinococcus granulosus jun protein 0.0084 0.073 0.0728
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0032 0.0109
Schistosoma mansoni 60S ribosomal protein L21 0.0039 0.0249 0.0248
Schistosoma mansoni amine GPCR 0.0131 0.1223 0.1222
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0071 0.059 0.1237
Schistosoma mansoni biogenic amine receptor 0.0131 0.1223 0.1222
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0568
Brugia malayi voltage-dependent calcium channel 0.0035 0.0214 0.0212
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.007 0.0574 0.0572
Brugia malayi jmjC domain containing protein 0.0037 0.0233 0.0231
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0579 0.0577
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0035 0.0212 0.021
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0016 0.0013 0.0011
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0215 0.0214
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0071 0.059 0.1899
Loa Loa (eye worm) hypothetical protein 0.0035 0.0209 0.0207
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0032 0.0109
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0056 0.0043
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni myosin xvIII 0.0131 0.1223 0.1222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0196 0.0668
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0056 0.0054
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0109 0.0212
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.1351 0.1315
Schistosoma mansoni glutamate receptor kainate 0.0163 0.1553 0.1552
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0035 0.0214 0.0212
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.003 0.016 0.0454
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0026 0.0024
Chlamydia trachomatis endonuclease IV 0.0077 0.0652 0.2191
Entamoeba histolytica disulphide oxidoreductase, putative 0.0071 0.059 0.1899
Schistosoma mansoni metabotropic glutamate receptor 0.0023 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.007 0.0574 0.0572
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0035 0.0214 0.0212
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0851 0.085
Brugia malayi Receptor family ligand binding region containing protein 0.0028 0.0139 0.0137
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0129 0.1203 0.1201
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0071 0.059 0.1237
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0212 0.021
Echinococcus multilocularis calmodulin 0.0025 0.0101 0.0099
Leishmania major hypothetical protein, conserved 0.0035 0.0214 0.0275
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0317 0.0316
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0299
Brugia malayi ion channel NompC 0.0035 0.0214 0.0212
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0035 0.0214 0.0212
Leishmania major mitochondrial DNA topoisomerase II 0.0158 0.15 0.1947
Onchocerca volvulus 0.0131 0.1223 0.1212
Trypanosoma brucei calmodulin 0.0025 0.0101 0.0129
Giardia lamblia Fructose-bisphosphate aldolase 0.0294 0.293 1
Schistosoma mansoni neurotransmitter gated ion channel 0.0016 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0056 0.0054
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0095 0.084 0.0829
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni jun-related protein 0.0069 0.0564 0.0562
Toxoplasma gondii transporter, cation channel family protein 0.0035 0.0214 0.0435
Schistosoma mansoni hypothetical protein 0.0048 0.0352 0.035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0337
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0249 0.0247
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Brugia malayi Protein kinase domain containing protein 0.0049 0.0357 0.0355
Schistosoma mansoni hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus transient receptor potential cation channel 0.0035 0.0214 0.0212
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0035 0.0214 0.0212
Loa Loa (eye worm) blistered cuticle protein 3 0.0073 0.061 0.0609
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Echinococcus multilocularis tumor protein p63 0.0339 0.3412 0.3411
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0209 0.0207
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.1223 0.1222
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0268 0.2658 0.5643
Schistosoma mansoni ap endonuclease 0.0019 0.0041 0.0039
Schistosoma mansoni acetylcholine receptor-related 0.0016 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Echinococcus granulosus epidermal growth factor receptor 0.0082 0.07 0.0699
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Onchocerca volvulus 0.0035 0.0212 0.0199
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0115 0.1055 0.1018
Schistosoma mansoni calcium-activated potassium channel 0.0035 0.0214 0.0212
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0233 0.0231
Echinococcus multilocularis conserved hypothetical protein 0.0035 0.0214 0.0212
Brugia malayi hypothetical protein 0.0041 0.0276 0.0274
Loa Loa (eye worm) hypothetical protein 0.0053 0.04 0.0399
Echinococcus granulosus transient receptor potential cation channel 0.0035 0.0214 0.0212
Brugia malayi ORL1-like opioid receptor 0.0131 0.1223 0.1222
Schistosoma mansoni chromobox protein 0.007 0.0579 0.0577
Brugia malayi olfactory channel protein osm-9 0.0036 0.0216 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0248 0.0846
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1729 0.5901
Mycobacterium tuberculosis Probable dehydrogenase 0.0175 0.1683 0.3566
Schistosoma mansoni glutamate receptor kainate 0.0163 0.1553 0.1552
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0016 0.0013 0.0011
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0274
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0041 0.0039
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0056 0.0054
Echinococcus granulosus neuropeptide receptor 0.0131 0.1223 0.1222
Toxoplasma gondii hypothetical protein 0.0041 0.0276 0.0568
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0035 0.0214 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0966 1 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.004 0.0265 0.0263
Schistosoma mansoni thyroid hormone receptor 0.002 0.0056 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0721 0.0719
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0033 0.0192 0.0151
Plasmodium falciparum transporter, putative 0.0041 0.0276 0.0568
Trypanosoma cruzi trypanothione reductase, putative 0.0268 0.2658 0.3452
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.3753 0.3752
Echinococcus granulosus glycine receptor subunit alpha 1 0.0035 0.0212 0.021
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0233 0.0192
Schistosoma mansoni hypothetical protein 0.0411 0.4163 0.4162
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Loa Loa (eye worm) adenylyl cyclase 3 0.0078 0.0666 0.0664
Echinococcus granulosus transient receptor potential gamma protein 0.0035 0.0214 0.0212
Brugia malayi Melatonin receptor type 1A 0.0131 0.1223 0.1222
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0009 0.0007
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0185 0.0184
Loa Loa (eye worm) hypothetical protein 0.0214 0.2089 0.2087
Loa Loa (eye worm) hypothetical protein 0.0029 0.0151 0.0149
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Trypanosoma cruzi DNA topoisomerase II, putative 0.0133 0.124 0.1609
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0025 0.0104 0.0102
Echinococcus multilocularis serotonin receptor 0.0376 0.3796 0.3795
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0131 0.1223 0.1222
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0056 0.0054
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0381 0.0493
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.004 0.0049
Brugia malayi steroid hormone receptor 0.002 0.0056 0.0054
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.054 0.0699
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.004 0.0265 0.0263
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0205 0.0417
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.059 0.0764
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.054 0.0538
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0041 0.0276 0.0274
Echinococcus multilocularis glycine receptor subunit beta 0.0035 0.0212 0.021
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0174 0.1672 0.167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0151 0.0515
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0082 0.0704 0.2293
Echinococcus granulosus potassium voltage gated channel protein 0.0035 0.0214 0.0212
Brugia malayi G protein-coupled receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0035 0.0214 0.0212
Echinococcus granulosus intermediate filament protein 0.0033 0.0185 0.0183
Echinococcus multilocularis voltage gated potassium channel 0.0044 0.0301 0.0299
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0041 0.004
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0035 0.0212 0.021
Echinococcus multilocularis fmrfamide receptor 0.0131 0.1223 0.1222
Echinococcus granulosus lamin 0.0033 0.0185 0.0183
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0071 0.059 0.0764
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0035 0.0214 0.0212
Onchocerca volvulus 0.0131 0.1223 0.1212
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0071 0.059 0.0588
Onchocerca volvulus 0.0035 0.0212 0.0199
Loa Loa (eye worm) hypothetical protein 0.005 0.0365 0.0363
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0109 0.0139
Brugia malayi Cytochrome P450 family protein 0.0019 0.0047 0.0046
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.2341 0.2339
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0056 0.0054
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0035 0.0212 0.021
Echinococcus granulosus two pore calcium channel protein 1 0.0035 0.0214 0.0212
Treponema pallidum sodium- and chloride- dependent transporter 0.0243 0.2397 0.8154
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0887 0.9176 0.9176
Echinococcus granulosus transient receptor potential cation channel 0.0035 0.0214 0.0212
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0271 0.0269
Onchocerca volvulus 0.0019 0.0042 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0056 0.0054
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0071 0.059 0.1899
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0035 0.0214 0.0212
Chlamydia trachomatis DNA gyrase subunit B 0.0065 0.0523 0.1687
Trichomonas vaginalis chromobox protein, putative 0.007 0.0579 0.1975
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0056 0.0054
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0381 0.0493
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0317 0.1083
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1729 0.5901
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0221 0.0284
Onchocerca volvulus 0.0035 0.0212 0.0199
Loa Loa (eye worm) hypothetical protein 0.0065 0.0526 0.0524
Schistosoma mansoni nAChR subunit 0.0035 0.0212 0.021
Onchocerca volvulus 0.0131 0.1223 0.1212
Echinococcus granulosus nmda type glutamate receptor 0.0102 0.0917 0.0915
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0071 0.059 0.1899
Giardia lamblia GTOR 0.0045 0.0317 0.0956
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni inositol monophosphatase 0.0037 0.0233 0.0231
Echinococcus granulosus DNA topoisomerase 2 alpha 0.014 0.1319 0.1318
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0095 0.084 0.0829
Schistosoma mansoni hypothetical protein 0.0069 0.0564 0.0562
Schistosoma mansoni glutamate receptor AMPA 0.0163 0.1553 0.1552
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0259 0.0257
Mycobacterium tuberculosis Probable reductase 0.0175 0.1683 0.3566
Entamoeba histolytica calmodulin, putative 0.0025 0.0101 0.0208
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0071 0.059 0.2013
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0071 0.059 0.0551
Loa Loa (eye worm) inositol-1 0.0037 0.0233 0.0231
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0275
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0275
Echinococcus multilocularis thioredoxin glutathione reductase 0.0462 0.4703 0.4702
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0274
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0107
Schistosoma mansoni hypothetical protein 0.0372 0.3753 0.3752
Echinococcus granulosus atrial natriuretic peptide receptor 0.0023 0.0083 0.0082
Loa Loa (eye worm) glutamate receptor 1 0.0163 0.1553 0.1552
Brugia malayi G-protein coupled receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis lamin dm0 0.0033 0.0185 0.0183
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.293 1
Brugia malayi MH2 domain containing protein 0.012 0.1104 0.1102
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.009 0.0049
Trypanosoma brucei calmodulin 0.0025 0.0101 0.0129
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0381 0.1176
Entamoeba histolytica protein kinase, putative 0.0031 0.0171 0.0448
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0151 0.0301
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0747 0.7695 1
Schistosoma mansoni nAChR subunit 0.0016 0.0013 0.0011
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0035 0.0212 0.021
Schistosoma mansoni glutamate receptor NMDA 0.0329 0.3303 0.3302
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0035 0.0214 0.0212
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0035 0.0214 0.0212
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0131 0.1223 0.1222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0056 0.0054
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.1223 0.1222
Echinococcus granulosus glycine receptor subunit alpha 1 0.0035 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0276 0.0274
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0038 0.0242 0.0696
Echinococcus granulosus neuropeptide FF receptor 2 0.0131 0.1223 0.1222
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0071 0.059 0.1899
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0233 0.0231
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0317 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0196 0.0668
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2571 0.8774
Schistosoma mansoni neurotransmitter gated ion channel 0.0016 0.0013 0.0011
Echinococcus granulosus 7TM GPCR rhodopsin 0.0131 0.1223 0.1222
Schistosoma mansoni tyrosine kinase 0.0039 0.0249 0.0247
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0651 0.6691 0.669
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0056 0.0043
Schistosoma mansoni opsin-like receptor 0.0131 0.1223 0.1222
Echinococcus granulosus tyrosine protein kinase Src64B 0.0039 0.0249 0.0247
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0205 0.0203
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0381 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0431
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.014 0.0477
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.009 0.0171
Schistosoma mansoni nuclear hormone receptor 0.002 0.0056 0.0054
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Chlamydia trachomatis thioredoxin reductase 0.0071 0.059 0.1948
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0249 0.0248
Echinococcus multilocularis potassium voltage gated channel protein 0.0035 0.0214 0.0212
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0747 0.7695 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0035 0.0212 0.021
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0042 0.004
Leishmania major calmodulin, putative 0.0025 0.0101 0.0129
Schistosoma mansoni neurotransmitter gated ion channel 0.0019 0.0042 0.004
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0039 0.0249 0.0247
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0056 0.0043
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Echinococcus multilocularis dnaJ subfamily B 0.0411 0.4163 0.4162
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0212 0.021
Loa Loa (eye worm) SRC-1 0.0039 0.0249 0.0248
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0056 0.0054
Leishmania major hypothetical protein, unknown function 0.0035 0.0214 0.0275
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0186 0.1794 0.1793
Schistosoma mansoni hypothetical protein 0.017 0.1633 0.1631
Schistosoma mansoni nAChR subunit 0.0035 0.0212 0.021
Schistosoma mansoni acetylcholine receptor subunit beta 0.0016 0.0013 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0203 0.0201
Echinococcus granulosus glutamate receptor subunit protein glur 0.007 0.0574 0.0572
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0287 0.0978
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0041 0.0039
Trichomonas vaginalis set domain proteins, putative 0.0239 0.2352 0.8025
Echinococcus multilocularis glutamate receptor 2 0.0163 0.1553 0.1552
Echinococcus multilocularis nAChR subunit 0.0019 0.0042 0.004
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Echinococcus multilocularis tyrosine protein kinase HCK 0.0031 0.0171 0.0169
Brugia malayi hypothetical protein 0.0035 0.0214 0.0212
Echinococcus granulosus fmrfamide receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0216 0.0214
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.054 0.0538
Schistosoma mansoni glutamate synthase 0.0071 0.059 0.0588
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0268 0.2658 0.2657
Echinococcus granulosus potassium voltage gated channel protein 0.0035 0.0214 0.0212
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0035 0.0212 0.021
Leishmania major calmodulin, putative 0.0025 0.0101 0.0129
Onchocerca volvulus 0.0131 0.1223 0.1212
Plasmodium vivax DNA topoisomerase II, putative 0.014 0.1319 0.2791
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0056 0.0054
Echinococcus multilocularis potassium voltage gated channel protein 0.0035 0.0214 0.0212
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0131 0.1223 0.1222
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0039 0.0249 0.0247
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0056 0.0054
Onchocerca volvulus 0.0041 0.0276 0.0264
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0006
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0071 0.059 0.2013
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0644 0.0642
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0205 0.0203
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0035 0.0214 0.0212
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.054 0.0538
Onchocerca volvulus 0.0131 0.1223 0.1212
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0109 0.0212
Echinococcus granulosus short transient receptor potential channel 6 0.0035 0.0214 0.0212
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0276 0.0274
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0568
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.009 0.0114
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Onchocerca volvulus 0.0033 0.0185 0.0172
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0466 0.4745 0.4744
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0275
Echinococcus granulosus sex peptide receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0243 0.2397 0.2396
Echinococcus granulosus adenylate cyclase 9 0.0078 0.0666 0.0664
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.007 0.0574 0.0572
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0071 0.059 0.1237
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Onchocerca volvulus 0.0083 0.0721 0.0709
Trypanosoma cruzi extracellular receptor, putative 0.0023 0.0083 0.0106
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0131 0.1223 0.1222
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0381 0.0379
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0056 0.0043
Echinococcus multilocularis snurportin 1 0.0372 0.3753 0.3752
Onchocerca volvulus 0.0243 0.2397 0.2387
Onchocerca volvulus 0.0042 0.0285 0.0272
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0032 0.0179 0.0177
Brugia malayi cation channel family protein 0.0035 0.0214 0.0212
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0071 0.059 0.0551
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0428 0.4347 0.4346
Giardia lamblia Calmodulin 0.0025 0.0101 0.0208
Echinococcus multilocularis glutamate receptor 2 0.0186 0.1794 0.1793
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0131 0.1223 0.1222
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0203 0.0261
Echinococcus granulosus ryanodine receptor 44f 0.0035 0.0214 0.0212
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0035 0.0212 0.021
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0186 0.1794 0.1793
Brugia malayi Importin beta-1 subunit 0.0035 0.0209 0.0207
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.014 0.1319 0.1318
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0082 0.07 0.0699
Onchocerca volvulus Dual oxidase homolog 0.0073 0.061 0.0598
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0109 0.0212
Schistosoma mansoni inositol monophosphatase 0.0037 0.0233 0.0231
Schistosoma mansoni voltage-gated ion channel 0.0035 0.0214 0.0212
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0381 0.0791
Echinococcus granulosus lamin dm0 0.0033 0.0185 0.0183
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0008 0.0006
Echinococcus multilocularis serotonin receptor 0.0376 0.3796 0.3795
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.1633 0.1622
Trypanosoma cruzi NADH dehydrogenase, putative 0.0071 0.059 0.0764
Loa Loa (eye worm) TK protein kinase 0.0035 0.0211 0.0209
Brugia malayi Cytochrome P450 family protein 0.0019 0.0047 0.0046
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0056 0.0054
Echinococcus multilocularis g protein coupled receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0243 0.2397 0.2396
Plasmodium vivax importin-beta 2, putative 0.0035 0.0209 0.0425
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0056 0.0054
Schistosoma mansoni tyrosine kinase 0.0039 0.0249 0.0247
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0268 0.2658 0.2627
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus voltage dependent calcium channel 0.0053 0.04 0.0399
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0209 0.0269
Schistosoma mansoni opsin-like receptor 0.0131 0.1223 0.1222
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0175 0.1683 0.3566
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0259 0.0257
Schistosoma mansoni hypothetical protein 0.0131 0.1223 0.1222
Echinococcus multilocularis conserved hypothetical protein 0.0693 0.7132 0.7132
Schistosoma mansoni glutamate receptor kainate 0.0163 0.1553 0.1552
Echinococcus granulosus tm gpcr rhodopsin 0.0651 0.6691 0.669
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0146 0.0145
Schistosoma mansoni glutamate receptor NMDA 0.0265 0.2627 0.2626
Brugia malayi Doublecortin family protein 0.004 0.0259 0.0257
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Echinococcus granulosus CalModulin family member cmd 1 0.0025 0.0101 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0056 0.0054
Chlamydia trachomatis glutamine binding protein 0.0038 0.0242 0.0594
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0071 0.059 0.0764
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0071 0.059 0.0588
Echinococcus granulosus chromobox protein 1 0.007 0.0579 0.0577
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0268 0.2658 0.3452
Trypanosoma cruzi calmodulin 0.0025 0.0101 0.0129
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0205 0.0264
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0498 0.0496
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.004 0.0265 0.0263
Schistosoma mansoni two-pore calcium channel 0.0035 0.0214 0.0212
Schistosoma mansoni biogenic amine (5HT) receptor 0.0887 0.9176 0.9176
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0039 0.0249 0.0247
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.001 0.0008
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0268 0.2658 0.2627
Schistosoma mansoni tyrosine kinase 0.008 0.068 0.0678
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0071 0.059 0.0588
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0186 0.1794 0.1793
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.004 0.0265 0.0263
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0276 0.0274
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0035 0.0212 0.021
Echinococcus multilocularis tyrosine protein kinase Blk 0.0035 0.0211 0.0209
Schistosoma mansoni tyrosine kinase 0.0151 0.1429 0.1428
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0381 0.13
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus potassium voltage gated channel subfamily H 0.007 0.0578 0.0576
Trypanosoma cruzi DNA topoisomerase II, putative 0.0133 0.124 0.1609
Echinococcus granulosus hypothetical protein 0.0824 0.8513 0.8513
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0071 0.059 0.1899
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0568
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0035 0.0211 0.0209
Brugia malayi Serotonin receptor 0.0593 0.6083 0.6082
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0268 0.2658 0.5643
Plasmodium falciparum glutathione reductase 0.0462 0.4703 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0056 0.0054
Brugia malayi Thioredoxin reductase 0.0462 0.4703 0.4702
Treponema pallidum hypothetical protein 0.0028 0.014 0.0342
Echinococcus multilocularis calmodulin 0.0025 0.0101 0.01
Mycobacterium ulcerans dehydrogenase 0.0071 0.059 0.0551
Onchocerca volvulus 0.004 0.0259 0.0247
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0268 0.2658 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0025 0.0101 0.01
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.073 0.0728
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0268 0.2658 0.2627
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0133 0.124 0.1609
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.004 0.0265 0.0263
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0268 0.2658 0.5643
Onchocerca volvulus 0.0131 0.1223 0.1212
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0082 0.0706 0.1483
Echinococcus granulosus nmda type glutamate receptor 0.0187 0.1807 0.1805
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1633 0.5572
Trypanosoma brucei calmodulin 0.0025 0.0101 0.0129
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.001 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2571 0.8774
Plasmodium vivax SET domain protein, putative 0.0031 0.0165 0.033
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0041 0.0141
Echinococcus multilocularis neuropeptide receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0035 0.0212 0.021
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.001 0.001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.1223 0.1222
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0071 0.059 0.0764
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0129 0.1203 0.1201
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0035 0.0214 0.0435
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0042 0.004
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0035 0.0212 0.021
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0026 0.0024
Onchocerca volvulus 0.0966 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0249 0.0247
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0243 0.2397 0.2395
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0041 0.0276 0.0274
Echinococcus multilocularis g-protein coupled receptor 0.0131 0.1223 0.1222
Schistosoma mansoni coup transcription factor 0.002 0.0056 0.0054
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.1223 0.1222
Schistosoma mansoni hypothetical protein 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0044
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0038 0.0242 0.0594
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0196 0.0668
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0056 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0337
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0329 0.3303 0.3302
Echinococcus granulosus receptor type guanylyl cyclase 0.0028 0.0139 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0099 0.0338
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0216 0.0214
Trypanosoma cruzi calmodulin, putative 0.0025 0.0101 0.0129
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0317 0.0956
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0041 0.0141
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus multilocularis transient receptor potential cation channel 0.0035 0.0214 0.0212
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.009 0.0171
Schistosoma mansoni voltage-dependent calcium channel 0.0035 0.0214 0.0212
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0056 0.0054
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0274
Loa Loa (eye worm) voltage-dependent calcium channel 0.0053 0.04 0.0399
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0205 0.0264
Echinococcus multilocularis G protein coupled receptor 139 0.0131 0.1223 0.1222
Echinococcus multilocularis sodium channel protein 0.0466 0.4745 0.4744
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.003 0.016 0.0321
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0652 0.137
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0041 0.0276 0.0274
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0129 0.1203 0.1201
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0082 0.0706 0.0667
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0035 0.0214 0.0212
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0035 0.0214 0.0212
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0035 0.0214 0.0212
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0301 0.0299
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0071 0.059 0.1237
Schistosoma mansoni hypothetical protein 0.0016 0.0009 0.0007
Echinococcus granulosus hyperpolarization activated cyclic 0.004 0.0265 0.0263
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0071 0.059 0.0764
Onchocerca volvulus 0.0131 0.1223 0.1212
Echinococcus granulosus two pore calcium channel protein 2 0.0035 0.0214 0.0212
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0265 0.0263
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.007 0.0578 0.0576
Schistosoma mansoni lamin 0.0033 0.0185 0.0183
Echinococcus granulosus potassium voltage gated channel protein 0.0035 0.0214 0.0212
Toxoplasma gondii transporter, cation channel family protein 0.0035 0.0214 0.0435
Echinococcus granulosus potassium voltage gated channel protein 0.0035 0.0214 0.0212
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0056 0.0054
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0039 0.0249 0.0247
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0041 0.0051
Plasmodium vivax glutathione reductase, putative 0.0462 0.4703 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Leishmania major hypothetical protein, conserved 0.0025 0.0109 0.0139
Echinococcus multilocularis geminin 0.017 0.1633 0.1631
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0124 0.0422
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0059 0.0461 0.0421
Onchocerca volvulus 0.0023 0.0083 0.0071
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0233 0.0231
Echinococcus granulosus glutamate synthase 0.0071 0.059 0.0588
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.009 0.0114
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0131 0.1223 0.1222
Toxoplasma gondii hypothetical protein 0.0018 0.003 0.0043
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0243 0.2397 0.2396
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0071 0.059 0.0764
Schistosoma mansoni rab6-interacting 0.004 0.0259 0.0257
Onchocerca volvulus 0.0131 0.1223 0.1212
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.059 0.0764
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0083 0.0082
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.009 0.0049
Loa Loa (eye worm) hypothetical protein 0.0095 0.0842 0.084
Onchocerca volvulus 0.0066 0.0539 0.0527
Brugia malayi Metabotropic glutamate receptor precursor. 0.0023 0.0083 0.0082
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0259 0.0257
Echinococcus multilocularis glutamate receptor subunit protein glur 0.007 0.0574 0.0572
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.0966 1 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0035 0.0212 0.021
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0276 0.0568
Loa Loa (eye worm) hypothetical protein 0.0018 0.003 0.0028
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0035 0.0214 0.0212
Schistosoma mansoni transient receptor potential channel 0.0035 0.0214 0.0212
Echinococcus granulosus potassium voltage gated channel protein 0.0035 0.0214 0.0212
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0071 0.059 0.0588
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0032 0.0109
Brugia malayi glutamate synthase 0.0071 0.059 0.0588
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0571 0.5846 0.7596
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0131 0.1223 0.1222
Schistosoma mansoni biogenic amine receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) thioredoxin reductase 0.0462 0.4703 0.4702
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0035 0.0212 0.021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0165 0.0163
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0221 0.0284
Treponema pallidum NADH oxidase 0.0268 0.2658 0.9058
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0008
Brugia malayi hypothetical protein 0.0016 0.0015 0.0013
Brugia malayi Dopamine receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0129 0.1203 0.1201
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0276 0.0274
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0372 0.3751 1
Toxoplasma gondii DNA topoisomerase 2, putative 0.014 0.1319 0.2791
Echinococcus granulosus glutamate NMDA receptor subunit 0.0329 0.3303 0.3302
Brugia malayi neuropeptide F receptor 0.0131 0.1223 0.1222
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0217 0.2124 0.2113
Brugia malayi GnHR receptor homolog 0.0131 0.1223 0.1222
Echinococcus granulosus GPCR family 2 0.0016 0.0009 0.0007
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0131 0.1223 0.1222
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Brugia malayi hypothetical protein 0.0237 0.2341 0.2339
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0963 0.9971 0.9971
Echinococcus multilocularis 0.0046 0.033 0.0328
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni nAChR subunit 0.0035 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0082 0.0705 0.0704
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0056 0.0054
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0249 0.0247
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0035 0.0214 0.0275
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0056 0.0054
Brugia malayi Probable DNA topoisomerase II 0.014 0.1319 0.1318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.022 0.0752
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0056 0.0054
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0185 0.0184
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.004 0.0265 0.0263
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0035 0.0211 0.0209
Onchocerca volvulus 0.0033 0.0185 0.0172
Echinococcus multilocularis jun protein 0.0084 0.073 0.0728
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.059 0.0764
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Loa Loa (eye worm) solute carrier family 6 member 4 0.0243 0.2397 0.2396
Echinococcus multilocularis potassium voltage gated channel protein 0.0035 0.0214 0.0212
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0429 0.0894
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0233 0.0476
Onchocerca volvulus 0.0131 0.1223 0.1212
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Loa Loa (eye worm) LGC-31 protein 0.0035 0.0212 0.021
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0071 0.059 0.2097
Echinococcus granulosus allatostatin A receptor 0.0131 0.1223 0.1222
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.059 0.2013
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0033 0.019 0.0189
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0016 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0966 1 1
Echinococcus multilocularis calmodulin 0.0025 0.0101 0.01
Echinococcus multilocularis short transient receptor potential channel 6 0.0035 0.0214 0.0212
Brugia malayi hypothetical protein 0.0025 0.0109 0.0107
Echinococcus granulosus calmodulin 0.0025 0.0101 0.0099
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.1223 0.1222
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0056 0.0014
Brugia malayi excitatory GABA receptor EXP-1A 0.0035 0.0212 0.021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.007 0.0578 0.0576
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0721 0.0719
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0071 0.059 0.0588
Echinococcus granulosus biogenic amine 5HT receptor 0.0887 0.9176 0.9176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0044
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0652 0.0651
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Brugia malayi Dopamine receptor protein 2 0.0131 0.1223 0.1222
Echinococcus granulosus g protein coupled receptor 0.0131 0.1223 0.1222
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0268 0.2658 0.2657
Brugia malayi Cation transporter family protein 0.0035 0.0212 0.021
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0035 0.0212 0.021
Echinococcus granulosus translocator protein 0.0966 1 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.054 0.0699
Leishmania major hypothetical protein, conserved 0.0034 0.0205 0.0264
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0268 0.2658 0.3452
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0071 0.059 0.1237
Brugia malayi MAP kinase sur-1 0.0051 0.0381 0.0379
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0205 0.0417
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0009 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0747 0.7695 1
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.2341 0.2339
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.059 0.0764
Echinococcus granulosus dnaJ subfamily B 0.0411 0.4163 0.4162
Trichomonas vaginalis calmodulin, putative 0.0025 0.0101 0.0346
Onchocerca volvulus 0.0131 0.1223 0.1212
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0047 0.0006
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0016 0.0013 0.0011
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0035 0.0214 0.0212
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0023 0.0083 0.0082
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0131 0.1223 0.1222
Echinococcus granulosus TRP transient receptor potential channel 0.0035 0.0214 0.0212
Echinococcus granulosus glutamate receptor NMDA 0.0079 0.0676 0.0674
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0352 0.035
Brugia malayi Bromodomain containing protein 0.0029 0.0151 0.0149
Echinococcus multilocularis shaker cognate 0.0035 0.0214 0.0212
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0033 0.0192 0.0151
Mycobacterium ulcerans tryptophan-rich sensory protein 0.0966 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.2048 0.2046
Giardia lamblia Glutamate synthase 0.0071 0.059 0.1899
Leishmania major trypanothione reductase 0.0462 0.4703 0.611
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0287 0.0274
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0174 0.1673 0.571
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0301 0.0299
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0428 0.434 0.5639
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Echinococcus granulosus tyrosine protein kinase Lyn 0.0039 0.0254 0.0252
Mycobacterium ulcerans hypothetical protein 0.002 0.0056 0.0014
Loa Loa (eye worm) ryanodine receptor 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.1223 0.1222
Plasmodium falciparum DNA topoisomerase 2 0.014 0.1319 0.2791
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0255 0.0871
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0009 0.0007
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Onchocerca volvulus 0.0131 0.1223 0.1212
Schistosoma mansoni neuropeptide receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0071 0.059 0.0764
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.293 1
Treponema pallidum thioredoxin reductase (trxB) 0.0071 0.059 0.1899
Loa Loa (eye worm) hypothetical protein 0.0071 0.059 0.0588
Echinococcus multilocularis neuropeptide receptor 0.0131 0.1223 0.1222
Trypanosoma cruzi calmodulin, putative 0.0025 0.0101 0.0129
Plasmodium falciparum importin beta, putative 0.0035 0.0209 0.0425
Echinococcus granulosus glycine receptor subunit beta 0.0035 0.0212 0.021
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0047 0.0059
Echinococcus multilocularis adenylate cyclase 9 0.0078 0.0666 0.0664
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0317 0.041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0165 0.0163
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.004 0.0265 0.0263
Brugia malayi Transient-receptor-potential like protein 0.0035 0.0214 0.0212
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.004 0.0265 0.0263
Loa Loa (eye worm) TOPoisomerase family member 0.014 0.1319 0.1318
Echinococcus multilocularis orexin receptor type 2 0.0131 0.1223 0.1222
Trypanosoma brucei protein kinase, putative 0.0051 0.0381 0.0493
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0035 0.0214 0.0212
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0721 0.0719
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0071 0.059 0.0551
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis chromobox protein 1 0.007 0.0579 0.0577
Onchocerca volvulus 0.0019 0.0042 0.0029
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0041 0.0276 0.0274
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.001 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0006
Brugia malayi metabotropic glutamate receptor type 2 0.0023 0.0083 0.0082
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0035 0.0212 0.021
Echinococcus granulosus glycine receptor subunit beta 0.0035 0.0212 0.021
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0255 0.0243
Schistosoma mansoni hypothetical protein 0.007 0.0574 0.0572
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0071 0.059 0.0588
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0139 0.0137
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0071 0.059 0.0551
Mycobacterium ulcerans epimerase 0.002 0.0056 0.0014
Loa Loa (eye worm) hypothetical protein 0.0095 0.0842 0.084
Echinococcus multilocularis voltage dependent calcium channel 0.0129 0.1203 0.1201
Onchocerca volvulus 0.0071 0.059 0.0578
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0039 0.0249 0.0247
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.059 0.2013
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0035 0.0212 0.021
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0185 0.0183
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0259 0.0257
Brugia malayi G protein-coupled receptor F59B2.13 0.0131 0.1223 0.1222
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0041 0.0068
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0035 0.0212 0.021
Echinococcus granulosus serotonin receptor 0.0131 0.1223 0.1222
Loa Loa (eye worm) voltage-gated calcium channel 0.0035 0.0214 0.0212
Plasmodium vivax ferrodoxin reductase, putative 0.0071 0.059 0.1237
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0249 0.0247
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0192 0.0369
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0016 0.0013 0.0011
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0151 0.0149
Echinococcus multilocularis calcium activated potassium channel 0.0036 0.0218 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1223 0.1222
Echinococcus granulosus tm gpcr rhodopsin 0.0131 0.1223 0.1222
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0233 0.0231
Loa Loa (eye worm) hypothetical protein 0.0036 0.0216 0.0214
Echinococcus granulosus tyrosine kinase 0.0025 0.0104 0.0102
Onchocerca volvulus Calmodulin homolog 0.0025 0.0101 0.0088
Echinococcus granulosus glutamate receptor 2 0.0186 0.1794 0.1793
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0035 0.0214 0.0212
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0071 0.059 0.2097
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1223 0.1222
Echinococcus granulosus tyrosine kinase 0.0035 0.0211 0.0209
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0276 0.0275
Plasmodium falciparum ferrodoxin reductase-like protein 0.0071 0.059 0.1237
Echinococcus granulosus neuropeptide receptor 0.0131 0.1223 0.1222
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0035 0.0214 0.0275
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.059 0.0764
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0035 0.0212 0.021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0056 0.0054
Brugia malayi bZIP transcription factor family protein 0.0084 0.073 0.0728
Echinococcus granulosus tyrosine protein kinase Src42A 0.0033 0.019 0.0189
Loa Loa (eye worm) TK/INSR protein kinase 0.0049 0.0357 0.0356
Loa Loa (eye worm) hypothetical protein 0.0035 0.0214 0.0212
Schistosoma mansoni importin beta-1 0.0035 0.0209 0.0207
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.073 0.0728
Echinococcus granulosus potassium large conductance calcium activated 0.0035 0.0214 0.0212
Trypanosoma brucei NADH dehydrogenase 0.0071 0.059 0.0764
Schistosoma mansoni thyroid hormone receptor 0.002 0.0056 0.0054
Brugia malayi hypothetical protein 0.0131 0.1223 0.1222
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0381 0.13
Brugia malayi hypothetical protein 0.0016 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0547 0.5597 0.5596
Echinococcus granulosus glycine receptor subunit alpha 1 0.0035 0.0212 0.021
Brugia malayi larval opioid receptor 0.0131 0.1223 0.1222
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0016 0.0013 0.0011
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0209 0.0425
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0011
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0019 0.0042 0.004
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0023 0.0083 0.0082
Onchocerca volvulus 0.0131 0.1223 0.1212
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0035 0.0214 0.0212
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.1223 0.1222
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Echinococcus granulosus neuropeptide s receptor 0.0593 0.6083 0.6082
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0186 0.1794 0.1793
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0249 0.0247
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0056 0.0054
Mycobacterium ulcerans ferredoxin reductase 0.0071 0.059 0.0551
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0082
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0131 0.1223 0.1222
Toxoplasma gondii endonuclease IV APN 0.0077 0.0652 0.137
Echinococcus multilocularis nAChR subunit 0.0035 0.0212 0.021
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0233 0.03
Schistosoma mansoni tyrosine kinase 0.0049 0.0357 0.0355
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0023 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Trypanosoma cruzi trypanothione reductase, putative 0.0462 0.4703 0.611
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0161 0.055
Schistosoma mansoni neuropeptide receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis transient receptor potential gamma protein 0.0035 0.0214 0.0212
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0033 0.0192 0.0389
Schistosoma mansoni transient receptor potential channel 4 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Trichomonas vaginalis chromobox protein, putative 0.007 0.0579 0.1975
Toxoplasma gondii selenide, water dikinase 0.0071 0.059 0.1237
Schistosoma mansoni adenoreceptor 0.0131 0.1223 0.1222
Leishmania major cytochrome p450-like protein 0.0019 0.0047 0.0059
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.2571 0.2569
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0381 0.13
Echinococcus granulosus tumor protein p63 0.0339 0.3412 0.3411
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.059 0.2013
Echinococcus granulosus tyrosine protein kinase HCK 0.0031 0.0171 0.0169
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0641 0.6587 0.856
Mycobacterium ulcerans endonuclease IV 0.0077 0.0652 0.0614
Schistosoma mansoni vesicular amine transporter 0.0035 0.0214 0.0212
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0165 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0317 0.1083
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.014 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0056 0.0054
Onchocerca volvulus 0.0028 0.0139 0.0126
Loa Loa (eye worm) hypothetical protein 0.0035 0.0212 0.021
Toxoplasma gondii hypothetical protein 0.0035 0.0214 0.0435
Schistosoma mansoni DNA topoisomerase II 0.014 0.1319 0.1318
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0056 0.0054
Echinococcus multilocularis potassium large conductance calcium activated 0.0035 0.0214 0.0212
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.1223 0.1222
Schistosoma mansoni voltage-gated potassium channel 0.0035 0.0214 0.0212
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0268 0.2658 0.2657
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0035 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Trichomonas vaginalis DNA topoisomerase II, putative 0.014 0.1319 0.4502
Brugia malayi putative neuropeptide receptor 0.0131 0.1223 0.1222
Echinococcus multilocularis somatostatin receptor 0.0131 0.1223 0.1222
Trichomonas vaginalis glutamate synthase, putative 0.0071 0.059 0.2013
Echinococcus granulosus epidermal growth factor receptor 0.0151 0.1429 0.1428
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0071 0.059 0.1899
Loa Loa (eye worm) hypothetical protein 0.0019 0.0042 0.004
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.009 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2571 0.8774
Schistosoma mansoni biogenic amine receptor 0.0131 0.1223 0.1222
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0056 0.0054
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0071 0.059 0.0551
Loa Loa (eye worm) hypothetical protein 0.0131 0.1223 0.1222
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.014 0.0179
Echinococcus multilocularis hyperpolarization activated cyclic 0.004 0.0265 0.0263
Echinococcus granulosus chromobox protein 1 0.007 0.0579 0.0577
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.054 0.0699

Activities

Activity type Activity value Assay description Source Reference
Bmax (binding) = 40.71 fmol/mg Displacement of [3H]Ro5-4864 from TSPO in putamen of healthy human ChEMBL. 19133775
Bmax (binding) = 61.67 fmol/mg Displacement of [3H]Ro5-4864 from TSPO in caudate nucleus of patient with Huntington's disease ChEMBL. 19133775

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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