Detailed information for compound 1526742

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 519.652 | Formula: C30H33NO5S
  • H donors: 1 H acceptors: 2 LogP: 7.76 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCc1cc(ccc1OCCCOc1cccc(c1)[C@H]1SC(=O)NC1=O)Oc1ccc(cc1)C(C)C
  • InChi: 1S/C30H33NO5S/c1-4-7-22-18-26(36-24-12-10-21(11-13-24)20(2)3)14-15-27(22)35-17-6-16-34-25-9-5-8-23(19-25)28-29(32)31-30(33)37-28/h5,8-15,18-20,28H,4,6-7,16-17H2,1-3H3,(H,31,32,33)/t28-/m1/s1
  • InChiKey: WHRFBVLXQHYSAS-MUUNZHRXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens peroxisome proliferator-activated receptor gamma Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus ecdysone induced protein 78C peroxisome proliferator-activated receptor gamma 477 aa 447 aa 28.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0124 0.0198 0.0198
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0068 0.1666
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.01 0.0602
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0054 0.0072 0.0072
Schistosoma mansoni acetylcholinesterase 0.0936 0.1668 0.1668
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0068 0.1666
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0072 0.0072
Echinococcus multilocularis neuropeptide s receptor 0.05 0.0879 0.0879
Trypanosoma cruzi major cysteine proteinase, putative 0.0041 0.0048 0.1124
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0052 0.0069 0.2602
Schistosoma mansoni immunophilin 0.0052 0.0069 0.0069
Schistosoma mansoni biogenic amine (5HT) receptor 0.0125 0.02 0.02
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.01 0.0539
Schistosoma mansoni inhibitor of apoptosis protein 0.0039 0.0045 0.0045
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0035 0.0395
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.003
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0073 0.0106 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0023 0.0456
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.018 0.108
Echinococcus granulosus pyruvate kinase 0.0036 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0035 0.0213
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.018 0.4686
Brugia malayi Carboxylesterase family protein 0.0936 0.1668 0.1668
Schistosoma mansoni caspase-7 (C14 family) 0.003 0.0028 0.0028
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.018 0.4686
Echinococcus multilocularis neuropeptide receptor 0.0125 0.02 0.02
Schistosoma mansoni adenoreceptor 0.0125 0.02 0.02
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0052 0.0069 0.0069
Leishmania major cathepsin L-like protease 0.0052 0.0068 0.1666
Echinococcus multilocularis acetylcholinesterase 0.554 1 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0026 0.0026
Brugia malayi prolyl oligopeptidase family protein 0.0057 0.0077 0.0077
Trichomonas vaginalis glutaminase, putative 0.0287 0.0493 0.2954
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0054 0.0072 0.0072
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.01 0.2542
Onchocerca volvulus 0.0125 0.02 0.1141
Schistosoma mansoni nuclear receptor 0.0026 0.002 0.002
Echinococcus multilocularis heat shock protein 90 0.0027 0.0023 0.0023
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.01 0.0602
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0052 0.0069 0.1688
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.554 1 1
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0023 0.0137
Echinococcus granulosus heat shock protein 0.0034 0.0035 0.0035
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0035 0.3124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0052 0.0069 0.0069
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0177
Brugia malayi Carboxylesterase family protein 0.0936 0.1668 0.1668
Schistosoma mansoni steroid hormone receptor ad4bp 0.0054 0.0072 0.0072
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0026 0.0026
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0936 0.1668 0.1668
Echinococcus multilocularis pyruvate kinase 0.007 0.01 0.01
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0054 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0023 0.0137
Onchocerca volvulus 0.0125 0.02 0.1141
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.001 0.0114
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0054 0.0072 0.0072
Echinococcus granulosus pyruvate kinase 0.007 0.01 0.01
Loa Loa (eye worm) G-protein coupled receptor 0.0125 0.02 0.02
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0177
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.003 0.003
Trichomonas vaginalis fk506-binding protein, putative 0.0052 0.0069 0.0412
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.003 0.2591
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.002 0.002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0125 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0125 0.02 0.02
Echinococcus multilocularis ecdysone induced protein 78C 0.0054 0.0072 0.0072
Schistosoma mansoni nuclear hormone receptor 0.0026 0.002 0.002
Onchocerca volvulus 0.0125 0.02 0.1141
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0054 0.0072 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0177
Echinococcus multilocularis fmrfamide receptor 0.0125 0.02 0.02
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0052 0.0069 0.0412
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0057 0.0077 0.1901
Echinococcus multilocularis BC026374 protein (S09 family) 0.0936 0.1668 0.1668
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0118 0.0118
Onchocerca volvulus 0.0125 0.02 0.1141
Schistosoma mansoni opsin-like receptor 0.0125 0.02 0.02
Onchocerca volvulus 0.0936 0.1668 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0125 0.02 0.02
Onchocerca volvulus 0.0026 0.002 0.0054
Schistosoma mansoni amine GPCR 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Echinococcus multilocularis RUN 0.0021 0.0011 0.0011
Loa Loa (eye worm) melatonin receptor type 1A 0.0125 0.02 0.02
Plasmodium vivax pyruvate kinase, putative 0.007 0.01 1
Schistosoma mansoni heat shock protein 0.0034 0.0035 0.0035
Echinococcus granulosus hypothetical protein 0.0125 0.02 0.02
Plasmodium falciparum heat shock protein 90 0.0034 0.0035 0.272
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0936 0.1668 0.1668
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) pyruvate kinase 0.007 0.01 0.01
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0027 0.0023 0.0973
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0075 0.0075
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.002 0.002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0125 0.02 0.02
Echinococcus granulosus g protein coupled receptor 0.0125 0.02 0.02
Brugia malayi nuclear hormone receptor 0.0054 0.0072 0.0072
Echinococcus multilocularis somatostatin receptor 0.0125 0.02 0.02
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0072 0.0072
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Brugia malayi follicle stimulating hormone receptor 0.0125 0.02 0.02
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Schistosoma mansoni pyruvate kinase 0.0036 0.0039 0.0039
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.003 0.0177
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.002 0.002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0125 0.02 0.02
Echinococcus multilocularis para nitrobenzyl esterase 0.0936 0.1668 0.1668
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.018 0.4686
Brugia malayi G protein-coupled receptor 0.0125 0.02 0.02
Brugia malayi 6-phosphofructokinase 0.0114 0.018 0.018
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0125 0.02 0.02
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0125 0.02 0.02
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0124 0.0198 0.0198
Echinococcus granulosus serotonin receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus granulosus para nitrobenzyl esterase 0.0936 0.1668 0.1668
Echinococcus granulosus biogenic amine 5HT receptor 0.0125 0.02 0.02
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0936 0.1668 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0125 0.02 0.02
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.0128 0.0128
Echinococcus granulosus tm gpcr rhodopsin 0.0125 0.02 0.02
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0378 1
Brugia malayi Cytochrome P450 family protein 0.0027 0.0022 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0054 0.0072 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0054 0.0072 0.0072
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Onchocerca volvulus 0.0026 0.002 0.0054
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus granulosus ecdysone induced protein 78C 0.0054 0.0072 0.0072
Brugia malayi Melatonin receptor type 1A 0.0125 0.02 0.02
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0052 0.0069 0.0378
Echinococcus multilocularis caspase 2 0.003 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Brugia malayi glutaminase DH11.1 0.0287 0.0493 0.0493
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0026 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0069 0.1688
Brugia malayi GnHR receptor homolog 0.0125 0.02 0.02
Leishmania major cathepsin L-like protease 0.0052 0.0068 0.1666
Schistosoma mansoni neuropeptide receptor 0.0125 0.02 0.02
Brugia malayi nuclear hormone receptor 0.0026 0.002 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0054 0.0072 0.0072
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0012 0.0012
Onchocerca volvulus 0.0125 0.02 0.1141
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0054 0.0072 0.0072
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Echinococcus multilocularis serotonin receptor 0.0125 0.02 0.02
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.002 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0936 0.1668 0.1668
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0035 0.0794
Brugia malayi hypothetical protein 0.003 0.0028 0.0028
Echinococcus multilocularis heat shock protein 0.0034 0.0035 0.0035
Schistosoma mansoni pyruvate kinase 0.007 0.01 0.01
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0054 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0064 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0125 0.02 0.02
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0039 0.0045 0.0045
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0027 0.0023 0.5
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0054 0.0072 0.0072
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0052 0.0069 0.5908
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0026 0.0026
Schistosoma mansoni BC026374 protein (S09 family) 0.0936 0.1668 0.1668
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.002 0.002
Onchocerca volvulus 0.0125 0.02 0.1141
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0039 0.0045 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0054 0.0072 0.0072
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0054 0.0072 0.0072
Schistosoma mansoni RAR-like nuclear receptor 0.0054 0.0072 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.02 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0011
Plasmodium vivax pyruvate kinase 2, putative 0.0036 0.0039 0.3091
Brugia malayi G-protein coupled receptor 0.0125 0.02 0.02
Echinococcus granulosus neuropeptide s receptor 0.05 0.0879 0.0879
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0085 0.0128 0.0128
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0054 0.0072 0.0072
Echinococcus granulosus tm gpcr rhodopsin 0.0125 0.02 0.02
Mycobacterium tuberculosis Conserved protein 0.0026 0.002 0.0086
Echinococcus multilocularis g-protein coupled receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0006 0.0006
Echinococcus granulosus neuropeptide Y receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Echinococcus granulosus fmrfamide receptor 0.0125 0.02 0.02
Schistosoma mansoni amine GPCR 0.0125 0.02 0.02
Echinococcus granulosus caspase 2 0.003 0.0028 0.0028
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0045 0.0056 0.0056
Plasmodium falciparum pyruvate kinase 0.007 0.01 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.002 0.002
Echinococcus multilocularis g protein coupled receptor 0.0125 0.02 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.02 0.02
Echinococcus granulosus 7tm_1 domain containing protein 0.0125 0.02 0.02
Onchocerca volvulus 0.0125 0.02 0.1141
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0125 0.02 0.02
Echinococcus multilocularis fk506 binding protein 0.0052 0.0069 0.0069
Mycobacterium tuberculosis Carboxylesterase LipT 0.0936 0.1668 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.007 0.01 0.01
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.018 0.1048
Brugia malayi Dopamine receptor 0.0125 0.02 0.02
Plasmodium vivax endoplasmin, putative 0.0034 0.0035 0.272
Loa Loa (eye worm) DR-78 0.0026 0.002 0.002
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.003 0.003
Onchocerca volvulus 0.003 0.0028 0.01
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0072 0.0072
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0936 0.1668 0.1668
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.003 0.0421
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0057 0.0077 0.0077
Schistosoma mansoni histamine h1 receptor 0.0125 0.02 0.02
Echinococcus multilocularis neuroligin 0.0936 0.1668 0.1668
Echinococcus granulosus dro:myosuppressin receptor 0.0125 0.02 0.02
Echinococcus multilocularis fmrfamide receptor 0.0125 0.02 0.02
Echinococcus multilocularis inhibitor of apoptosis protein 0.0039 0.0045 0.0045
Echinococcus granulosus heat shock protein 90 0.0034 0.0035 0.0035
Brugia malayi steroid hormone receptor 0.0054 0.0072 0.0072
Brugia malayi Steroid receptor seven-up type 2 0.0054 0.0072 0.0072
Onchocerca volvulus 0.0936 0.1668 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus multilocularis orexin receptor type 2 0.0125 0.02 0.02
Echinococcus multilocularis g protein coupled receptor 0.0125 0.02 0.02
Onchocerca volvulus 0.0125 0.02 0.1141
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0085 0.0128 0.0128
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0936 0.1668 0.1668
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0011 0.0011
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0169 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Schistosoma mansoni nuclear hormone receptor 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0057 0.0077 0.0077
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0125 0.02 0.02
Brugia malayi AKH receptor 0.0125 0.02 0.02
Schistosoma mansoni coup transcription factor 0.0054 0.0072 0.0072
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.002 0.0385
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0052 0.0069 0.6445
Echinococcus granulosus g protein coupled receptor 0.0125 0.02 0.02
Echinococcus granulosus sex peptide receptor 0.0125 0.02 0.02
Echinococcus granulosus 7TM GPCR rhodopsin 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.554 1 1
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0052 0.0069 0.6445
Loa Loa (eye worm) phosphofructokinase 0.0114 0.018 0.018
Brugia malayi putative neuropeptide receptor NPR1 0.0125 0.02 0.02
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.003 0.2494
Brugia malayi 6-phosphofructokinase 0.0114 0.018 0.018
Brugia malayi Endoplasmin precursor 0.0034 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Onchocerca volvulus 0.0125 0.02 0.1141
Schistosoma mansoni myosin xvIII 0.0125 0.02 0.02
Brugia malayi G protein-coupled receptor F59B2.13 0.0125 0.02 0.02
Schistosoma mansoni polycystin 1-related 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Chlamydia trachomatis pyruvate kinase 0.007 0.01 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.002 0.002
Echinococcus granulosus inhibitor of apoptosis protein 0.0039 0.0045 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0054 0.0072 0.0072
Echinococcus granulosus neuropeptide receptor A26 0.05 0.0879 0.0879
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0068 0.1666
Schistosoma mansoni hypothetical protein 0.003 0.0028 0.0028
Echinococcus multilocularis pyruvate kinase 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0567 0.0999 0.5978
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Brugia malayi hypothetical protein 0.0043 0.0052 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.018 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.003 0.2494
Echinococcus granulosus neuropeptides capa receptor 0.0125 0.02 0.02
Loa Loa (eye worm) pyruvate kinase-PB 0.0049 0.0062 0.0062
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.018 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0054 0.0072 0.0072
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0125 0.02 0.02
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0936 0.1668 0.1668
Onchocerca volvulus 0.0936 0.1668 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0011 0.0011
Brugia malayi Cytochrome P450 family protein 0.0018 0.0006 0.0006
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0011 0.0011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.002 0.002
Schistosoma mansoni neuropeptide receptor 0.0125 0.02 0.02
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0125 0.02 0.02
Schistosoma mansoni retinoic acid receptor RXR 0.0054 0.0072 0.0072
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.018 0.1048
Echinococcus granulosus biogenic amine 5HT receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus multilocularis heat shock protein 90 0.0034 0.0035 0.0035
Loa Loa (eye worm) steroid hormone receptor 0.0054 0.0072 0.0072
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0022 0.0429
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0442 0.0774 0.0774
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Mycobacterium leprae Probable pyruvate kinase PykA 0.007 0.01 0.5424
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Schistosoma mansoni gliotactin 0.0936 0.1668 0.1668
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Echinococcus granulosus neuropeptides capa receptor 0.0125 0.02 0.02
Echinococcus granulosus tachykinin peptides receptor 99D 0.0125 0.02 0.02
Loa Loa (eye worm) acetylcholinesterase 1 0.554 1 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.002 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.003 0.2053
Echinococcus granulosus neuropeptide FF receptor 2 0.0125 0.02 0.02
Echinococcus multilocularis neuropeptide receptor A26 0.05 0.0879 0.0879
Schistosoma mansoni lipoxygenase 0.0086 0.013 0.013
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0023 0.0456
Brugia malayi nuclear receptor RXR 0.0029 0.0026 0.0026
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0125 0.02 0.02
Schistosoma mansoni immunophilin 0.0045 0.0056 0.0056
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0052 0.0069 0.1688
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.02 0.02
Plasmodium falciparum pyruvate kinase 2 0.0036 0.0039 0.3091
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0026 0.0026
Onchocerca volvulus Deterin homolog 0.0039 0.0045 0.0202
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.018 1
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0035 0.0794
Leishmania major cytochrome p450-like protein 0.0027 0.0022 0.0429
Brugia malayi Dopamine receptor protein 1 0.0125 0.02 0.02
Brugia malayi G-protein coupled receptor 0.0125 0.02 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Brugia malayi RE15519p 0.0125 0.02 0.02
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0035 0.0395
Onchocerca volvulus Bile acid receptor homolog 0.0054 0.0072 0.0368
Schistosoma mansoni hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.003 0.2053
Echinococcus granulosus alpha 1A adrenergic receptor 0.0125 0.02 0.02
Trypanosoma brucei pyruvate kinase 1, putative 0.007 0.01 0.2542
Brugia malayi phosphofructokinase 0.0114 0.018 0.018
Echinococcus granulosus pyruvate kinase 0.0036 0.0039 0.0039
Brugia malayi nuclear receptor RXR 0.0026 0.002 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0125 0.02 0.02
Echinococcus multilocularis neuropeptide Y receptor 0.0125 0.02 0.02
Echinococcus multilocularis 0.0018 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Toxoplasma gondii pyruvate kinase PyKII 0.0036 0.0039 0.3474
Brugia malayi hypothetical protein 0.0026 0.002 0.002
Echinococcus granulosus pyruvate kinase 0.0036 0.0039 0.0039
Echinococcus granulosus endoplasmin 0.0027 0.0023 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0022 0.0429
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Echinococcus granulosus neuropeptide receptor 0.0125 0.02 0.02
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0125 0.02 0.02
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.002 0.0122
Brugia malayi ecdysone receptor 0.0026 0.002 0.002
Schistosoma mansoni cytochrome P450 0.0018 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0021 0.0011 0.0011
Schistosoma mansoni neuropeptide receptor 0.0125 0.02 0.02
Echinococcus granulosus Dipeptidyl peptidase 9 0.0057 0.0077 0.0077
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0035 0.0035
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Onchocerca volvulus 0.0936 0.1668 1
Echinococcus multilocularis neuropeptide Y receptor 0.0125 0.02 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0936 0.1668 1
Plasmodium vivax SET domain protein, putative 0.0031 0.003 0.2156
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Brugia malayi nuclear receptor NHR-88 0.0054 0.0072 0.0072
Echinococcus granulosus carboxylesterase 5A 0.554 1 1
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0035 0.0794
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.002 0.0385
Loa Loa (eye worm) endoplasmin 0.0034 0.0035 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Onchocerca volvulus Neuropeptide F receptor homolog 0.0125 0.02 0.1141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0054 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.0098 0.0585
Echinococcus multilocularis G-protein coupled receptor, putative 0.0125 0.02 0.02
Loa Loa (eye worm) cytochrome P450 0.0018 0.0006 0.0006
Echinococcus granulosus g protein coupled receptor 0.0125 0.02 0.02
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0072 0.0072
Echinococcus granulosus neuroligin 0.0936 0.1668 0.1668
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0072 0.0072
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0073 0.0106 0.0106
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0054 0.0072 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0936 0.1668 0.1668
Brugia malayi Nuclear hormone receptor E75 0.0026 0.002 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0125 0.02 0.02
Echinococcus multilocularis sex peptide receptor 0.0125 0.02 0.02
Echinococcus multilocularis neuropeptides capa receptor 0.0125 0.02 0.02
Echinococcus multilocularis pyruvate kinase 0.0036 0.0039 0.0039
Brugia malayi hypothetical protein 0.0029 0.0026 0.0026
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.003 0.0853
Schistosoma mansoni rab6-interacting 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0936 0.1668 0.1668
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0026 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.018 0.108
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0069 0.1688
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0169 0.028 0.028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Schistosoma mansoni biogenic amine (5HT) receptor 0.0125 0.02 0.02
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0125 0.02 0.02
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0035 0.3124
Schistosoma mansoni pyruvate kinase 0.007 0.01 0.01
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0011 0.0011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0125 0.02 0.02
Onchocerca volvulus 0.0039 0.0045 0.0202
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.018 0.108
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0035 0.0794
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Brugia malayi Dopamine receptor protein 2 0.0125 0.02 0.02
Loa Loa (eye worm) G-protein coupled receptor 0.0125 0.02 0.02
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Brugia malayi ORL1-like opioid receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Schistosoma mansoni zinc finger protein 0.0026 0.002 0.002
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0057 0.0077 0.1901
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0057 0.0077 0.1901
Loa Loa (eye worm) glutaminase 2 0.0287 0.0493 0.0493
Onchocerca volvulus 0.0936 0.1668 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0073 0.0106 0.0106
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0012 0.007
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0026
Mycobacterium ulcerans hypothetical protein 0.0026 0.002 0.0086
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0012 0.007
Onchocerca volvulus 0.0125 0.02 0.1141
Echinococcus multilocularis pyruvate kinase 0.0036 0.0039 0.0039
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0054 0.0072 0.0368
Leishmania major peptidylprolyl isomerase-like protein 0.0052 0.0069 0.1688
Brugia malayi putative neuropeptide receptor 0.0125 0.02 0.02
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.01 0.0539
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0125 0.02 0.02
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Brugia malayi neuropeptide F receptor 0.0125 0.02 0.02
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.0128 0.0128
Loa Loa (eye worm) FKBP5 protein 0.0052 0.0069 0.0069
Schistosoma mansoni glutaminase 0.0287 0.0493 0.0493
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0125 0.02 0.02
Brugia malayi larval opioid receptor 0.0125 0.02 0.02
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0169 0.028 0.162
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0177
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0052 0.0069 0.5908
Loa Loa (eye worm) pyruvate kinase 0.007 0.01 0.01
Schistosoma mansoni amine GPCR 0.0125 0.02 0.02
Schistosoma mansoni growth hormone secretagogue receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.002 0.0385
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0057 0.0077 0.7479
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0125 0.02 0.02
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0052 0.0069 0.0069
Schistosoma mansoni opsin-like receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Loa Loa (eye worm) hypothetical protein 0.0936 0.1668 0.1668
Schistosoma mansoni hypothetical protein 0.0125 0.02 0.02
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.002 0.0086
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.002 0.002
Brugia malayi Carboxylesterase family protein 0.554 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.0369 0.0369
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0011 0.0011
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0125 0.02 0.02
Echinococcus multilocularis endoplasmin 0.0027 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0936 0.1668 0.1668
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0012 0.0012
Echinococcus granulosus apoptotic protease activating factor 1 0.003 0.0028 0.0028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0072 0.0072
Echinococcus multilocularis acetylcholinesterase 0.554 1 1
Schistosoma mansoni loxhd1 0.0021 0.0011 0.0011
Brugia malayi prolyl oligopeptidase family protein 0.0169 0.028 0.028
Brugia malayi Cytochrome P450 family protein 0.0027 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0054 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus granulosus BC026374 protein S09 family 0.0936 0.1668 0.1668
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0072 0.0072
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.002 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.003 0.2053
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0125 0.02 0.02
Echinococcus multilocularis thyroid hormone receptor alpha 0.0054 0.0072 0.0072
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0023 0.0137
Brugia malayi ecdysteroid receptor 0.0054 0.0072 0.0072
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.002 0.002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.002 0.0054
Schistosoma mansoni biogenic amine receptor 0.0125 0.02 0.02
Schistosoma mansoni rab6-interacting 0.0021 0.0011 0.0011
Schistosoma mansoni neuropeptide F-like receptor 0.0125 0.02 0.02
Loa Loa (eye worm) glutaminase 0.0287 0.0493 0.0493
Echinococcus multilocularis neuropeptide FF receptor 2 0.0125 0.02 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0026
Echinococcus granulosus orexin receptor type 2 0.0125 0.02 0.02
Brugia malayi heat shock protein 90 0.0034 0.0035 0.0035
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0057 0.0077 0.1901
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0049 0.0062 0.0062
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0125 0.02 0.02
Loa Loa (eye worm) carboxylesterase 0.554 1 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Schistosoma mansoni neuropeptide receptor 0.0125 0.02 0.02
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0054 0.0072 0.0072
Brugia malayi Nuclear hormone receptor E75 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Brugia malayi Pyruvate kinase, M2 isozyme 0.007 0.01 0.01
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Brugia malayi Pyruvate kinase, muscle isozyme 0.007 0.01 0.01
Trichomonas vaginalis immunophilin, putative 0.0052 0.0069 0.0412
Schistosoma mansoni biogenic amine receptor 0.0125 0.02 0.02
Echinococcus multilocularis neuropeptide receptor 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Brugia malayi Carboxylesterase family protein 0.0936 0.1668 0.1668
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0054 0.0072 0.0072
Brugia malayi tailless protein 0.0026 0.002 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0177
Echinococcus granulosus peptide allatostatin:somatostatin 0.0125 0.02 0.02
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0052 0.0069 0.0412
Leishmania major pyruvate kinase 0.007 0.01 0.2542
Onchocerca volvulus 0.0125 0.02 0.1141
Loa Loa (eye worm) carboxylesterase 0.0936 0.1668 0.1668
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0072 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0054 0.0072 0.0072
Schistosoma mansoni neuropeptide F-like receptor 0.0125 0.02 0.02
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Brugia malayi Pre-SET motif family protein 0.0218 0.0369 0.0369
Leishmania major pyruvate kinase 0.007 0.01 0.2542
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0085 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Brugia malayi Pre-SET motif family protein 0.0031 0.003 0.003
Echinococcus multilocularis FTZ F1 alpha 0.0054 0.0072 0.0072
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0035 0.272
Echinococcus granulosus tm gpcr rhodopsin 0.0125 0.02 0.02
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.018 0.018
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0125 0.02 0.02
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0012 0.0012
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0054 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0054 0.0072 0.0072
Plasmodium falciparum endoplasmin, putative 0.0021 0.0012 0.0047
Schistosoma mansoni neuroligin 3 (S09 family) 0.0936 0.1668 0.1668
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Brugia malayi conserved hypotetical protein 0.0026 0.002 0.002
Trypanosoma brucei heat shock protein, putative 0.0034 0.0035 0.0794
Echinococcus granulosus allatostatin A receptor 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Onchocerca volvulus 0.0125 0.02 0.1141
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.002 0.002
Giardia lamblia Pyruvate kinase 0.0036 0.0039 0.2047
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.01 0.0539
Loa Loa (eye worm) neuropeptide F receptor 0.0125 0.02 0.02
Echinococcus granulosus acetylcholinesterase 0.554 1 1
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Brugia malayi sulfakinin receptor protein 0.0125 0.02 0.02
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0047 0.006 0.1447
Onchocerca volvulus 0.0125 0.02 0.1141
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0125 0.02 0.1141
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0022 0.0022
Brugia malayi Tachykinin-like peptides receptor 99D 0.0125 0.02 0.02
Loa Loa (eye worm) neuropeptide F receptor 0.0125 0.02 0.02
Echinococcus multilocularis serotonin receptor 0.0125 0.02 0.02
Echinococcus granulosus heat shock protein 90 0.0027 0.0023 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0125 0.02 0.02
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.002 0.002
Echinococcus multilocularis g protein coupled receptor 0.0125 0.02 0.02
Brugia malayi photoreceptor-specific nuclear receptor 0.0054 0.0072 0.0072
Schistosoma mansoni neuropeptide f receptor 76f 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.554 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0072 0.0072
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0022 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0035 0.0794
Mycobacterium ulcerans pyruvate kinase 0.007 0.01 0.0568
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0052 0.0069 0.2602
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0085 0.0128 0.0128
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0054 0.0072 0.0072
Loa Loa (eye worm) prolyl oligopeptidase 0.0169 0.028 0.028
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.003 0.003
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.018 1
Loa Loa (eye worm) hypothetical protein 0.0936 0.1668 0.1668
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0085 0.0128 0.0128
Schistosoma mansoni hypothetical protein 0.0018 0.0006 0.0006
Onchocerca volvulus 0.0031 0.003 0.0116
Echinococcus multilocularis pyruvate kinase 0.0036 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0012
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0021 0.0012 0.0012
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0073 0.0106 0.0106
Trichomonas vaginalis set domain proteins, putative 0.0248 0.0423 0.2539
Mycobacterium ulcerans carboxylesterase, LipT 0.0936 0.1668 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0012 0.0012
Echinococcus multilocularis allatostatin A receptor 0.0125 0.02 0.02
Schistosoma mansoni heat shock protein 0.0034 0.0035 0.0035
Echinococcus multilocularis apoptotic protease activating factor 1 0.003 0.0028 0.0028
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.007 0.01 0.0568
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0022 0.0429
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.02 0.02
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0012 0.0012
Brugia malayi nuclear receptor NHR-88 0.0026 0.002 0.002
Trypanosoma brucei pyruvate kinase 1 0.007 0.01 0.2542
Leishmania major fk506-binding protein 1-like protein 0.0052 0.0069 0.1688
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.002 0.002
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.01 0.2542
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0039 0.0045 0.0045
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.018 0.018
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0023 0.0102
Entamoeba histolytica pyruvate kinase, putative 0.0049 0.0062 0.2164
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.002 0.0086
Echinococcus granulosus neuropeptide receptor 0.0125 0.02 0.02
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0057 0.0077 0.1901
Trypanosoma brucei hypothetical protein, conserved 0.0223 0.0378 1
Brugia malayi Doublecortin family protein 0.0021 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Leishmania major cathepsin L-like protease 0.0052 0.0068 0.1666
Schistosoma mansoni amine GPCR 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0026
Brugia malayi Carboxylesterase family protein 0.0936 0.1668 0.1668
Onchocerca volvulus Cell death protein 3 homolog 0.003 0.0028 0.01
Echinococcus multilocularis carboxylesterase 5A 0.554 1 1
Trypanosoma cruzi cruzipain precursor, putative 0.0052 0.0068 0.1666
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.0098 0.0585
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.002 0.0086
Echinococcus granulosus pyruvate kinase 0.007 0.01 0.01
Brugia malayi nuclear receptor NHR-67 0.0026 0.002 0.002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0085 0.0128 0.0128
Onchocerca volvulus 0.0248 0.0423 0.2488
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0012 0.0012
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0039 0.0045 0.0045
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0125 0.02 0.02
Schistosoma mansoni opsin-like receptor 0.0125 0.02 0.02
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.002 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0125 0.02 0.02
Onchocerca volvulus Protein ultraspiracle homolog 0.0054 0.0072 0.0368
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0177
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0023 0.0456
Echinococcus granulosus FTZ F1 alpha 0.0054 0.0072 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.003 0.2053
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Brugia malayi Serotonin receptor 0.0125 0.02 0.02
Brugia malayi Cell death protein 3 precursor 0.003 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Brugia malayi neuropeptide F receptor 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0029 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0125 0.02 0.02
Schistosoma mansoni endoplasmin 0.0034 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0125 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0039 0.0045 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0125 0.02 0.02
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0035 0.1621
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0125 0.02 0.02
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0125 0.02 0.02
Mycobacterium tuberculosis Probable oxidoreductase 0.0567 0.0999 0.5978
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.003 0.003
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.002 0.002
Onchocerca volvulus 0.0054 0.0072 0.0368
Echinococcus multilocularis dro:myosuppressin receptor 0.0125 0.02 0.02
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0052 0.0069 0.1688
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0169 0.028 0.028
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0069 0.1688
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Onchocerca volvulus 0.0125 0.02 0.1141
Brugia malayi Serotonin receptor 0.0125 0.02 0.02
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.003 0.2494
Toxoplasma gondii pyruvate kinase PyK1 0.007 0.01 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.002 0.002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0125 0.02 0.02
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0026
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.018 0.018
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0028 0.0028
Echinococcus granulosus RUN 0.0021 0.0011 0.0011
Echinococcus multilocularis neuropeptides capa receptor 0.0125 0.02 0.02
Echinococcus granulosus G protein coupled receptor 139 0.0125 0.02 0.02
Schistosoma mansoni immunophilin 0.0052 0.0069 0.0069
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.0045 0.0045
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0045 0.0056 0.0056
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0125 0.02 0.02
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0022 0.0022
Onchocerca volvulus 0.0125 0.02 0.1141
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0035 0.0794
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0022 0.0096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0072 0.0072
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.018 0.018
Echinococcus multilocularis G protein coupled receptor 139 0.0125 0.02 0.02
Echinococcus granulosus acetylcholinesterase 0.554 1 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0936 0.1668 0.1668
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0378 1
Onchocerca volvulus 0.0125 0.02 0.1141
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0035 0.0794
Echinococcus granulosus g-protein coupled receptor 0.0125 0.02 0.02
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0035 0.0794
Brugia malayi Cytochrome P450 family protein 0.0056 0.0075 0.0075
Schistosoma mansoni amine GPCR 0.0125 0.02 0.02
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.003 0.003
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0052 0.0069 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0011 0.0011
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.002 0.002
Schistosoma mansoni biogenic amine receptor 0.0125 0.02 0.02
Loa Loa (eye worm) carboxylesterase 0.0936 0.1668 0.1668
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Loa Loa (eye worm) hypothetical protein 0.0936 0.1668 0.1668
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0039 0.0045 0.0045
Loa Loa (eye worm) pyruvate kinase 0.007 0.01 0.01
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.018 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0026
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0054 0.0072 0.0072
Echinococcus granulosus somatostatin receptor 0.0125 0.02 0.02
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0052 0.0069 0.2913
Schistosoma mansoni alpha-1 adrenergic receptor 0.0125 0.02 0.02
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0052 0.0069 0.0069
Leishmania major hypothetical protein, conserved 0.0223 0.0378 1
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.018 0.108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0068 0.1666
Mycobacterium ulcerans glutaminase 0.0287 0.0493 0.2929
Brugia malayi cytochrome P450 0.0018 0.0006 0.0006
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.003 0.003
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0125 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0039 0.0045 0.0045
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.002 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0054 0.0072 0.0072
Giardia lamblia Pyruvate kinase 0.007 0.01 1
Onchocerca volvulus 0.0125 0.02 0.1141
Loa Loa (eye worm) hypothetical protein 0.0125 0.02 0.02
Brugia malayi hypothetical protein 0.0026 0.002 0.002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0125 0.02 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.02 0.02
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0052 0.0069 0.0069
Schistosoma mansoni nuclear receptor 0.0026 0.002 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0072 0.0072
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0054 0.0072 0.0072
Leishmania major heat shock protein 83-1 0.0034 0.0035 0.0794
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0125 0.02 0.02
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.002 0.002
Trichomonas vaginalis spcc417.12 protein, putative 0.0936 0.1668 1
Loa Loa (eye worm) TYRA-2 protein 0.0125 0.02 0.02
Schistosoma mansoni endoplasmin 0.0034 0.0035 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.02 0.02
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0936 0.1668 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0085 0.0128 0.0128
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0052 0.0069 0.0069
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.018 1
Brugia malayi hypothetical protein 0.0125 0.02 0.02
Echinococcus multilocularis pyruvate kinase 0.007 0.01 0.01
Mycobacterium ulcerans hypothetical protein 0.0026 0.002 0.0086
Schistosoma mansoni lipoxygenase 0.0124 0.0198 0.0198
Echinococcus granulosus neuropeptide Y receptor 0.0125 0.02 0.02
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0023 0.0102
Loa Loa (eye worm) hypothetical protein 0.0043 0.0052 0.0052

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 170 nM Displacement of radio-labeled full agonist from PPARgamma receptor ChEMBL. 21482446

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.