TDR Targets

Basic information

Technical information

TDR Targets ID: 1528159
Name: (1R,3aS,4S,7aS)-5-ethenyl-1,3a,4,7a-tetrameth yl-1,2,3,4,6,7-hexahydroinden-5-ol
MW: 222.366 | Formula: C15H26O
H donors: 1 H acceptors: 1 LogP: 4.28 Rotable bonds: 1
Rule of 5 violations (Lipinski): 1
SMILES: C=CC1(O)CC[C@@]2([C@@]([C@@H]1C)(C)CC[C@H]2C)C
InChi: 1S/C15H26O/c1-6-15(16)10-9-13(4)11(2)7-8-14(13,5)12(15)3/h6,11-12,16H,1,7-10H2,2-5H3/t11-,12+,13+,14+,15?/m1/s1
InChiKey: TUCSIUBDOHTKKQ-JFKAKTETSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(1R,3aS,4S,7aS)-1,3a,4,7a-tetramethyl-5-vinyl-1,2,3,4,6,7-hexahydroinden-5-ol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	deoxyribonuclease 1 2	0.0019	0.0176	0.0167
Brugia malayi	proteasome subunit alpha type 1	0.0053	0.0644	0.0933
Echinococcus multilocularis	Proteasome subunit alpha type 7	0.0053	0.0644	0.0636
Trypanosoma cruzi	proteasome alpha 3 subunit, putative	0.0053	0.0644	0.1489
Entamoeba histolytica	proteasome subunit alpha type 6, putative	0.0053	0.0644	0.1353
Echinococcus multilocularis	20S proteasome subunit alpha 6	0.0053	0.0644	0.0636
Brugia malayi	proteasome subunit beta type 1	0.021	0.2806	0.4221
Trypanosoma cruzi	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Brugia malayi	jmjC domain containing protein	0.0015	0.012	0.0137
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0487	0.6605	1
Schistosoma mansoni	aldehyde dehydrogenase	0.0063	0.0772	0.0764
Schistosoma mansoni	proteasome subunit alpha 7 (T01 family)	0.0053	0.0644	0.0636
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Loa Loa (eye worm)	jmjC domain-containing protein	0.0015	0.012	0.0134
Trypanosoma brucei	proteasome subunit beta type-5, putative	0.0271	0.3637	1
Echinococcus multilocularis	Proteasome subunit alpha type 7	0.0053	0.0644	0.0636
Trypanosoma cruzi	proteasome beta 6 subunit, putative	0.021	0.2806	0.7637
Toxoplasma gondii	exonuclease III APE	0.0095	0.1217	0.312
Loa Loa (eye worm)	proteasome subunit beta type 2	0.013	0.1705	0.2545
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0621	0.0895
Entamoeba histolytica	proteasome subunit beta type 5 precursor, putative	0.0271	0.3637	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.012	0.0134
Schistosoma mansoni	netrin receptor unc5	0.0052	0.0621	0.0613
Trypanosoma brucei	proteasome alpha 3 subunit, putative	0.0053	0.0644	0.1489
Brugia malayi	CXXC zinc finger family protein	0.0028	0.03	0.041
Trypanosoma brucei	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Schistosoma mansoni	hypothetical protein	0.0019	0.0176	0.0167
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0176	0.0218
Trypanosoma cruzi	cytochrome P450, putative	0.0026	0.0276	0.0442
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0053	0.0644	0.1489
Schistosoma mansoni	cytochrome P450	0.0018	0.0156	0.0147
Loa Loa (eye worm)	jmjC domain-containing protein	0.0015	0.012	0.0134
Echinococcus granulosus	JmjC domain containing protein 4	0.0015	0.012	0.0112
Brugia malayi	Cytochrome P450 family protein	0.0026	0.0276	0.0373
Leishmania major	proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative	0.021	0.2806	0.7637
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0271	0.3637	1
Echinococcus multilocularis	proteasome (prosome macropain) subunit alpha	0.0053	0.0644	0.0636
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Schistosoma mansoni	neutral sphingomyelinase	0.0019	0.0176	0.0167
Schistosoma mansoni	cpg binding protein	0.003	0.0322	0.0314
Plasmodium vivax	proteasome subunit alpha type-5, putative	0.0053	0.0644	0.1489
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0063	0.0772	0.0764
Echinococcus multilocularis	phd:f box containing protein	0.0015	0.012	0.0112
Loa Loa (eye worm)	proteasome subunit alpha type 3	0.0053	0.0644	0.0931
Giardia lamblia	20S proteasome alpha subunit 7	0.0053	0.0644	0.1353
Toxoplasma gondii	proteasome subunit alpha1, putative	0.0053	0.0644	0.1489
Toxoplasma gondii	endonuclease/exonuclease/phosphatase family protein	0.0019	0.0176	0.0157
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0095	0.1217	0.312
Brugia malayi	Proteasome A-type and B-type family protein	0.0053	0.0644	0.0933
Schistosoma mansoni	hypothetical protein	0.0402	0.5441	0.5437
Loa Loa (eye worm)	cytochrome P450	0.0018	0.0156	0.0188
Echinococcus multilocularis	JmjC domain containing protein 4	0.0015	0.012	0.0112
Schistosoma mansoni	cpg binding protein	0.003	0.0322	0.0314
Entamoeba histolytica	proteasome subunit beta type 6 precursor, putative	0.0053	0.0644	0.1353
Trichomonas vaginalis	carbon catabolite repressor protein, putative	0.0019	0.0176	0.0483
Trypanosoma brucei	Inositol phosphosphingolipids phospholipase C	0.0019	0.0176	0.0157
Toxoplasma gondii	aldehyde dehydrogenase	0.0063	0.0772	0.1852
Loa Loa (eye worm)	CCR4-NOT transcription complex subunit 6 family protein	0.0019	0.0176	0.0218
Plasmodium vivax	hypothetical protein, conserved	0.0019	0.0176	0.0157
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0063	0.0772	0.177
Loa Loa (eye worm)	endonuclease/Exonuclease/phosphatase	0.0019	0.0176	0.0218
Echinococcus multilocularis	microtubule associated protein 2	0.0734	1	1
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Trichomonas vaginalis	ap endonuclease, putative	0.0095	0.1217	0.3347
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0095	0.1217	1
Mycobacterium leprae	probable proteasome (alpha subunit) PrcA	0.0053	0.0644	0.1403
Plasmodium falciparum	carbon catabolite repressor protein 4, putative	0.0019	0.0176	0.0157
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0052	0.0621	0.0895
Entamoeba histolytica	proteasome subunit alpha type 1, putative	0.0053	0.0644	0.1353
Plasmodium falciparum	proteasome subunit beta type-3, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	proteasome subunit alpha type-5, putative	0.0053	0.0644	0.1489
Plasmodium vivax	proteasome subunit alpha type-6, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	proteasome beta 3 subunit, putative	0.0053	0.0644	0.1489
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0053	0.0644	0.1489
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.013	0.1705	0.1698
Echinococcus granulosus	proteasome prosome macropain subunit beta	0.021	0.2806	0.28
Toxoplasma gondii	proteasome beta subunit	0.0053	0.0644	0.1489
Trypanosoma cruzi	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0063	0.0772	0.177
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0019	0.0176	0.0157
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.0271	0.3637	1
Schistosoma mansoni	protein phosphatase 2C	0.0015	0.012	0.0112
Leishmania major	cytochrome p450-like protein	0.0018	0.0156	0.01
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Loa Loa (eye worm)	proteasome subunit alpha type 7-1	0.0053	0.0644	0.0931
Toxoplasma gondii	endonuclease/exonuclease/phosphatase family protein	0.0019	0.0176	0.0157
Toxoplasma gondii	proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	endonuclease/exonuclease/phosphatase, putative	0.0019	0.0176	0.0157
Loa Loa (eye worm)	hypothetical protein	0.0015	0.012	0.0134
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0176	0.0218
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0095	0.1217	0.312
Trypanosoma brucei	inositol/phosphatidylinositol phosphatase, putative	0.0019	0.0176	0.0157
Leishmania major	proteasome beta-1 subunit, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	proteasome subunit beta type-2, putative	0.013	0.1705	0.4507
Toxoplasma gondii	proteasome subunit alpha type, putative	0.0053	0.0644	0.1489
Loa Loa (eye worm)	cytochrome P450 family protein	0.0026	0.0276	0.0371
Trypanosoma cruzi	proteasome beta-1 subunit, putative	0.0053	0.0644	0.1489
Brugia malayi	proteasome subunit beta type 2	0.013	0.1705	0.2547
Entamoeba histolytica	proteasome subunit alpha type 3, putative	0.0053	0.0644	0.1353
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0095	0.1217	0.305
Leishmania major	lanosterol 14-alpha-demethylase, putative	0.0018	0.0156	0.01
Echinococcus multilocularis	dnaJ subfamily B	0.0402	0.5441	0.5437
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0053	0.0644	0.1489
Echinococcus granulosus	proteasome subunit beta type 6	0.0053	0.0644	0.0636
Echinococcus multilocularis	proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta	0.0053	0.0644	0.0636
Brugia malayi	Proteasome A-type and B-type family protein	0.0053	0.0644	0.0933
Trypanosoma brucei	proteasome alpha 2 subunit, putative	0.0053	0.0644	0.1489
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0009	0.0032	0.0024
Giardia lamblia	Proteasome subunit beta type 1	0.021	0.2806	0.7599
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	0.0017	0.0143	0.0134
Echinococcus granulosus	dnaJ subfamily B	0.0402	0.5441	0.5437
Echinococcus multilocularis	proteasome subunit alpha type 2	0.0053	0.0644	0.0636
Echinococcus multilocularis	Ankyrin	0.0052	0.0624	0.0616
Leishmania major	endonuclease/exonuclease protein-like protein	0.0019	0.0176	0.0157
Mycobacterium ulcerans	proteasome PrcB	0.0271	0.3637	1
Schistosoma mansoni	proteasome subunit alpha 4 (T01 family)	0.0053	0.0644	0.0636
Toxoplasma gondii	cytochrome p450 superfamily protein	0.0018	0.0156	0.01
Toxoplasma gondii	peptidase, T1 family protein	0.0053	0.0644	0.1489
Trypanosoma cruzi	proteasome beta 3 subunit, putative	0.0053	0.0644	0.1489
Giardia lamblia	Proteasome subunit beta type 2	0.013	0.1705	0.4419
Trypanosoma cruzi	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0095	0.1217	0.121
Trypanosoma brucei	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Toxoplasma gondii	endonuclease/exonuclease/phosphatase family protein	0.0019	0.0176	0.0157
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0053	0.0644	0.1489
Plasmodium falciparum	proteasome subunit beta type-7, putative	0.0053	0.0644	0.1489
Schistosoma mansoni	proteasome subunit alpha 3 (T01 family)	0.0053	0.0644	0.0636
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0095	0.1217	0.301
Giardia lamblia	Proteasome subunit beta type 3	0.0053	0.0644	0.1353
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0271	0.3637	0.5483
Brugia malayi	jmjC domain containing protein	0.0058	0.0715	0.1042
Trypanosoma cruzi	proteasome beta 7 subunit, putative	0.0053	0.0644	0.1489
Leishmania major	hypothetical protein, conserved	0.0019	0.0176	0.0157
Trypanosoma brucei	proteasome beta 2 subunit, putative	0.0053	0.0644	0.1489
Brugia malayi	follicle stimulating hormone receptor	0.0487	0.6605	1
Trypanosoma brucei	proteasome subunit beta type-2, putative	0.013	0.1705	0.4507
Echinococcus granulosus	proteasome prosome macropain	0.0271	0.3637	0.3631
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0063	0.0772	0.0764
Trypanosoma cruzi	ATP-dependent protease subunit HslV, putative	0.0053	0.0644	0.1489
Echinococcus granulosus	proteasome subunit beta type 7	0.0053	0.0644	0.0636
Schistosoma mansoni	ap endonuclease	0.0095	0.1217	0.121
Plasmodium vivax	proteasome subunit beta type-5, putative	0.0271	0.3637	1
Echinococcus multilocularis	proteasome subunit beta type 7	0.0053	0.0644	0.0636
Loa Loa (eye worm)	PAS-3 protein	0.0053	0.0644	0.0931
Giardia lamblia	Proteasome subunit beta type 5 precursor	0.0271	0.3637	1
Giardia lamblia	Proteasome subunit beta type 9 precursor	0.0053	0.0644	0.1353
Plasmodium vivax	proteasome subunit alpha type-2, putative	0.0053	0.0644	0.1489
Trichomonas vaginalis	skeletal muscle/kidney enriched inositol 5-phosphatase, putative	0.0019	0.0176	0.0483
Leishmania major	pantothenate kinase subunit, putative	0.0019	0.0176	0.0157
Trichomonas vaginalis	ap endonuclease, putative	0.0095	0.1217	0.3347
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.021	0.2806	0.7715
Plasmodium vivax	proteasome subunit alpha type-4, putative	0.0053	0.0644	0.1489
Toxoplasma gondii	heat shock protein hslv, putative	0.0053	0.0644	0.1489
Loa Loa (eye worm)	endonuclease/Exonuclease/phosphatase	0.0019	0.0176	0.0218
Trypanosoma brucei	Proteasome subunit A N-terminal signature/Proteasome subunit, putative	0.0053	0.0644	0.1489
Onchocerca volvulus	Notchless protein homolog	0.0053	0.0644	1
Trypanosoma cruzi	pantothenate kinase subunit, putative	0.0019	0.0176	0.0157
Trypanosoma brucei	proteasome alpha 1 subunit, putative	0.0053	0.0644	0.1489
Echinococcus multilocularis	traf and tnf receptor associated protein	0.0019	0.0176	0.0167
Schistosoma mansoni	nocturnin	0.0019	0.0176	0.0167
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.03	0.0408
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Trypanosoma cruzi	proteasome beta 2 subunit, putative	0.0053	0.0644	0.1489
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0032	0.0000096378
Trypanosoma cruzi	proteasome alpha 1 subunit, putative	0.0053	0.0644	0.1489
Brugia malayi	Cytochrome P450 family protein	0.0075	0.0949	0.1397
Plasmodium falciparum	proteasome subunit beta type-5	0.0271	0.3637	1
Loa Loa (eye worm)	endonuclease/Exonuclease/phosphatase	0.0019	0.0176	0.0218
Giardia lamblia	Proteasome subunit beta type 4 precursor	0.0053	0.0644	0.1353
Plasmodium falciparum	proteasome subunit alpha type-4, putative	0.0053	0.0644	0.1489
Echinococcus multilocularis	cpg binding protein	0.003	0.0322	0.0314
Plasmodium falciparum	proteasome subunit beta type-4	0.0053	0.0644	0.1489
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0095	0.1217	0.1803
Loa Loa (eye worm)	endonuclease/Exonuclease/phosphatase	0.0019	0.0176	0.0218
Schistosoma mansoni	proteasome subunit alpha 6 (T01 family)	0.0053	0.0644	0.0636
Schistosoma mansoni	subfamily T1A non-peptidase homologue (T01 family)	0.0053	0.0644	0.0636
Leishmania major	proteasome beta 3 subunit, putative	0.0053	0.0644	0.1489
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.013	0.1705	0.4688
Schistosoma mansoni	proteasome subunit beta 4 (T01 family)	0.0053	0.0644	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0015	0.012	0.0134
Trypanosoma brucei	proteasome beta 7 subunit	0.0053	0.0644	0.1489
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0026	0.0276	0.0345
Plasmodium vivax	proteasome subunit beta type-1, putative	0.021	0.2806	0.7637
Brugia malayi	jmjC domain containing protein	0.0015	0.012	0.0137
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0009	0.0032	0.0024
Toxoplasma gondii	proteasome subunit beta type 7 precursor, putative	0.0053	0.0644	0.1489
Echinococcus multilocularis	proteasome (prosome, macropain)	0.0271	0.3637	0.3631
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0053	0.0644	0.1489
Echinococcus granulosus	death domain containing protein	0.0052	0.0621	0.0613
Trypanosoma cruzi	proteasome beta-1 subunit, putative	0.0053	0.0644	0.1489
Echinococcus granulosus	traf and tnf receptor associated protein	0.0019	0.0176	0.0167
Brugia malayi	proteasome subunit alpha type 4	0.0053	0.0644	0.0933
Loa Loa (eye worm)	proteasome subunit beta type 1	0.021	0.2806	0.4219
Echinococcus granulosus	Ankyrin	0.0052	0.0624	0.0616
Loa Loa (eye worm)	CYP4Cod1	0.0026	0.0276	0.0371
Schistosoma mansoni	cript-related	0.0019	0.0176	0.0167
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0095	0.1217	0.312
Trichomonas vaginalis	type IV inositol 5-phosphatase, putative	0.0019	0.0176	0.0483
Echinococcus granulosus	lysine specific demethylase 5A	0.0058	0.0715	0.0708
Toxoplasma gondii	proteasome subunit beta type, putative	0.0271	0.3637	1
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0053	0.0644	0.1489
Loa Loa (eye worm)	cytochrome P450 family protein	0.0026	0.0276	0.0371
Entamoeba histolytica	proteasome subunit alpha type 3, putative	0.0053	0.0644	0.1353
Trypanosoma brucei	proteasome alpha 7 subunit, putative	0.0053	0.0644	0.1489
Entamoeba histolytica	proteasome subunit alpha type 4, putative	0.0053	0.0644	0.1353
Brugia malayi	proteasome subunit alpha type 2	0.0053	0.0644	0.0933
Mycobacterium leprae	proteasome (beta subunit) PrcB	0.0271	0.3637	1
Echinococcus multilocularis	ankyrin repeat and death domain containing protein	0.0052	0.0621	0.0613
Trypanosoma cruzi	inositol 5-phosphatase 1, putative	0.0019	0.0176	0.0157
Schistosoma mansoni	ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related	0.0015	0.012	0.0112
Leishmania major	proteasome alpha 7 subunit, putative	0.0053	0.0644	0.1489
Leishmania major	hypothetical protein, conserved	0.0019	0.0176	0.0157
Toxoplasma gondii	endonuclease/exonuclease/phosphatase family protein	0.0019	0.0176	0.0157
Schistosoma mansoni	ap endonuclease	0.0095	0.1217	0.121
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Mycobacterium tuberculosis	Probable exported protein	0.0019	0.0176	0.0057
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Schistosoma mansoni	phd/f-box containing protein	0.0015	0.012	0.0112
Mycobacterium tuberculosis	Proteasome alpha subunit PrcA; assembles with beta subunit PrcB.	0.0053	0.0644	0.1403
Trypanosoma cruzi	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Brugia malayi	Cytochrome P450 family protein	0.0026	0.0276	0.0373
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0058	0.0715	0.0708
Echinococcus granulosus	netrin receptor unc 5	0.0052	0.0621	0.0613
Schistosoma mansoni	proteasome subunit beta 3 (T01 family)	0.0053	0.0644	0.0636
Trypanosoma cruzi	proteasome alpha 1 subunit, putative	0.0053	0.0644	0.1489
Leishmania major	hypothetical protein, conserved	0.0019	0.0176	0.0157
Leishmania major	proteasome alpha 3 subunit, putative	0.0053	0.0644	0.1489
Plasmodium vivax	endonuclease/exonuclease/phosphatase domain containing protein	0.0019	0.0176	0.0157
Leishmania major	proteasome beta 5 subunit, putative	0.0271	0.3637	1
Plasmodium vivax	proteasome subunit alpha type-1, putative	0.0053	0.0644	0.1489
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0053	0.0644	0.1489
Leishmania major	proteasome alpha 7 subunit, putative	0.0053	0.0644	0.1489
Trypanosoma brucei	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Giardia lamblia	20S proteasome alpha subunit 5	0.0053	0.0644	0.1353
Leishmania major	proteasome beta 7 subunit, putative	0.0053	0.0644	0.1489
Echinococcus multilocularis	inositol polyphosphate 5 phosphatase OCRL 1	0.0019	0.0176	0.0167
Echinococcus multilocularis		0.0018	0.0156	0.0147
Loa Loa (eye worm)	proteasome subunit alpha type 1	0.0053	0.0644	0.0931
Plasmodium vivax	proteasome subunit beta type-4, putative	0.0053	0.0644	0.1489
Entamoeba histolytica	proteasome subunit alpha type 5, putative	0.0053	0.0644	0.1353
Echinococcus multilocularis	lysine specific demethylase 6a	0.0015	0.012	0.0112
Toxoplasma gondii	endonuclease/exonuclease/phosphatase family protein	0.0019	0.0176	0.0157
Plasmodium vivax	proteasome subunit alpha type-3, putative	0.0053	0.0644	0.1489
Plasmodium vivax	proteasome subunit beta type-6, putative	0.0053	0.0644	0.1489
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.006	0.0736	0.0728
Loa Loa (eye worm)	jmjC domain-containing protein	0.0015	0.012	0.0134
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0624	0.0901
Trypanosoma cruzi	proteasome subunit alpha type-5, putative	0.0053	0.0644	0.1489
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Echinococcus granulosus	proteasome subunit alpha type 6	0.0053	0.0644	0.0636
Leishmania major	proteasome alpha 1 subunit, putative	0.0053	0.0644	0.1489
Brugia malayi	Cytochrome P450 family protein	0.0018	0.0156	0.019
Schistosoma mansoni	proteasome catalytic subunit 2 (T01 family)	0.0053	0.0644	0.0636
Schistosoma mansoni	phosphatidylserine receptor	0.0015	0.012	0.0112
Trypanosoma cruzi	mitochondrial protein 99, putative	0.0019	0.0176	0.0157
Echinococcus multilocularis	proteasome subunit alpha type 6	0.0053	0.0644	0.0636
Schistosoma mansoni	subfamily T1A non-peptidase homologue (T01 family)	0.0053	0.0644	0.0636
Trypanosoma cruzi	RNA-editing complex protein MP100, putative	0.0019	0.0176	0.0157
Schistosoma mansoni	hypothetical protein	0.0018	0.0156	0.0147
Brugia malayi	jmjC domain containing protein	0.0057	0.0693	0.1008
Brugia malayi	Proteasome subunit alpha type 7-1	0.0053	0.0644	0.0933
Echinococcus multilocularis	proteasome (prosome, macropain) subunit, beta	0.013	0.1705	0.1698
Brugia malayi	proteasome subunit alpha type 6	0.0053	0.0644	0.0933
Toxoplasma gondii	proteasome subunit beta type 1, putative	0.021	0.2806	0.7637
Schistosoma mansoni	jumonji domain containing protein	0.0015	0.012	0.0112
Plasmodium falciparum	proteasome subunit alpha type-7, putative	0.0053	0.0644	0.1489
Echinococcus granulosus	lysine specific demethylase 6a	0.0015	0.012	0.0112
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Brugia malayi	exodeoxyribonuclease III family protein	0.0095	0.1217	0.1805
Entamoeba histolytica	proteasome subunit alpha type 7, putative	0.0053	0.0644	0.1353
Plasmodium falciparum	proteasome subunit alpha type-1, putative	0.0053	0.0644	0.1489
Echinococcus multilocularis	jumonji domain containing 1A	0.0015	0.012	0.0112
Echinococcus multilocularis	nuclear factor of activated T cells 5	0.0592	0.8048	0.8046
Trypanosoma brucei	inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative	0.0019	0.0176	0.0157
Plasmodium falciparum	endonuclease/exonuclease/phosphatase family protein, putative	0.0019	0.0176	0.0157
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0053	0.0644	0.0931
Echinococcus granulosus	jumonji domain containing 1A	0.0015	0.012	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0176	0.0218
Toxoplasma gondii	20S proteasome subunit beta 7, putative	0.0053	0.0644	0.1489
Plasmodium falciparum	proteasome subunit alpha type-5, putative	0.0053	0.0644	0.1489
Echinococcus granulosus	proteasome prosome macropain subunit beta	0.013	0.1705	0.1698
Plasmodium falciparum	exodeoxyribonuclease III, putative	0.0019	0.0176	0.0157
Giardia lamblia	20S proteasome alpha subunit 4	0.0053	0.0644	0.1353
Echinococcus granulosus	nuclear factor of activated T cells 5	0.0592	0.8048	0.8046
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0095	0.1217	0.312
Plasmodium falciparum	proteasome subunit alpha type-3, putative	0.0053	0.0644	0.1489
Plasmodium falciparum	carbon catabolite repressor protein 4, putative	0.0019	0.0176	0.0157
Plasmodium falciparum	proteasome subunit beta type-1, putative	0.021	0.2806	0.7637
Loa Loa (eye worm)	endonuclease/Exonuclease/phosphatase	0.0019	0.0176	0.0218
Trypanosoma cruzi	20S proteasome subunit	0.013	0.1705	0.4507
Entamoeba histolytica	proteasome subunit alpha type 7, putative	0.0053	0.0644	0.1353
Schistosoma mansoni	proteasome subunit beta 3 (T01 family)	0.0053	0.0644	0.0636
Echinococcus multilocularis	proteasome (prosome macropain) subunit beta type	0.0053	0.0644	0.0636
Plasmodium vivax	endonuclease/exonuclease/phosphatase domain containing protein	0.0019	0.0176	0.0157
Onchocerca volvulus	Netrin receptor homolog	0.0052	0.0621	0.9501
Entamoeba histolytica	proteasome subunit beta type 3, putative	0.0053	0.0644	0.1353
Schistosoma mansoni	proteasome catalytic subunit 1 (T01 family)	0.0053	0.0644	0.0636
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0057	0.0693	0.0685
Echinococcus multilocularis	CCR4 NOT transcription complex subunit 6	0.0019	0.0176	0.0167
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0019	0.0176	0.0157
Schistosoma mansoni	proteasome subunit alpha 1 (T01 family)	0.0053	0.0644	0.0636
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0095	0.1217	0.301
Leishmania major	cytochrome p450-like protein	0.0018	0.0156	0.01
Echinococcus granulosus	phd:f box containing protein	0.0015	0.012	0.0112
Leishmania major	inositol phosphosphingolipid phospholipase C-Like	0.0019	0.0176	0.0157
Schistosoma mansoni	synaptojanin	0.0019	0.0176	0.0167
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0052	0.0621	0.0897
Toxoplasma gondii	proteasome subunit alpha type 5-2, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	Lanosterol 14-alpha demethylase	0.0018	0.0156	0.01
Leishmania major	inositol/phosphatidylinositol phosphatase, putative	0.0019	0.0176	0.0157
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0095	0.1217	0.305
Schistosoma mansoni	retinoblastoma-binding protein 4 (rbbp4)	0.0052	0.0624	0.0616
Schistosoma mansoni	microtubule-associated protein tau	0.0734	1	1
Loa Loa (eye worm)	cytochrome P450 family protein	0.0075	0.0949	0.1395
Schistosoma mansoni	carbon catabolite repressor protein	0.0019	0.0176	0.0167
Brugia malayi	20S proteasome alpha5 subunit	0.0053	0.0644	0.0933
Brugia malayi	jmjC domain containing protein	0.0015	0.012	0.0137
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	0.0017	0.0143	0.0134
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.0053	0.0644	0.0636
Echinococcus granulosus	endonuclease exonuclease phosphatase	0.0019	0.0176	0.0167
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	Lanosterol 14-alpha demethylase	0.0018	0.0156	0.01
Trypanosoma brucei	proteasome beta 6 subunit	0.021	0.2806	0.7637
Brugia malayi	Proteasome A-type and B-type family protein	0.0053	0.0644	0.0933
Leishmania major	hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B	0.0053	0.0644	0.1489
Leishmania major	proteasome beta 2 subunit, putative	0.013	0.1705	0.4507
Mycobacterium ulcerans	proteasome PrcA	0.0053	0.0644	0.1403
Toxoplasma gondii	endonuclease/exonuclease/phosphatase family protein	0.0019	0.0176	0.0157
Leishmania major	cytochrome p450-like protein	0.0026	0.0276	0.0442
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0057	0.0693	0.0685
Echinococcus granulosus	proteasome prosome macropain subunit alpha	0.0053	0.0644	0.0636
Trypanosoma brucei	proteasome alpha 7 subunit	0.0053	0.0644	0.1489
Plasmodium falciparum	proteasome subunit beta type-6, putative	0.0053	0.0644	0.1489
Giardia lamblia	Proteasome subunit beta type 7 precursor	0.0053	0.0644	0.1353
Trypanosoma cruzi	hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B	0.0053	0.0644	0.1489
Trypanosoma cruzi	proteasome alpha 3 subunit, putative	0.0053	0.0644	0.1489
Trypanosoma brucei	ATP-dependent protease subunit HslV	0.0053	0.0644	0.1489
Schistosoma mansoni	ankyrin 23/unc44	0.0052	0.0621	0.0613
Trichomonas vaginalis	sphingomyelinase C 2 precursor, putative	0.0019	0.0176	0.0483
Echinococcus granulosus	CCR4 NOT transcription complex subunit 6	0.0019	0.0176	0.0167
Trypanosoma cruzi	proteasome subunit alpha type-1, putative	0.0053	0.0644	0.1489
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Trypanosoma cruzi	proteasome alpha 2 subunit, putative	0.0053	0.0644	0.1489
Echinococcus multilocularis	subfamily T1A non peptidase ue	0.0053	0.0644	0.0636
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.0271	0.3637	1
Toxoplasma gondii	proteasome subunit alpha type 1, putative	0.0053	0.0644	0.1489
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Schistosoma mansoni	proteasome subunit alpha 2 (T01 family)	0.0053	0.0644	0.0636
Echinococcus granulosus	ankyrin repeat and death domain containing protein	0.0052	0.0621	0.0613
Entamoeba histolytica	proteasome subunit beta type 7-B precursor, putative	0.0053	0.0644	0.1353
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0053	0.0644	0.1771
Echinococcus granulosus	20S proteasome subunit alpha 6	0.0053	0.0644	0.0636
Echinococcus granulosus	subfamily T1A non peptidase ue	0.0053	0.0644	0.0636
Echinococcus granulosus	cpg binding protein	0.003	0.0322	0.0314
Echinococcus multilocularis	neutral sphingomyelinase	0.0019	0.0176	0.0167
Loa Loa (eye worm)	20S proteasome alpha5 subunit	0.0053	0.0644	0.0931
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0053	0.0644	0.0931
Entamoeba histolytica	proteasome subunit alpha type 2-A, putative	0.0053	0.0644	0.1353
Echinococcus granulosus	cytochrome P450 2K1	0.0018	0.0156	0.0147
Leishmania major	proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative)	0.0053	0.0644	0.1489
Giardia lamblia	20S proteasome alpha subunit 2	0.0053	0.0644	0.1353
Echinococcus multilocularis	synaptojanin 1	0.0019	0.0176	0.0167
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Echinococcus multilocularis	lysine specific demethylase 5A	0.0057	0.0693	0.0685
Echinococcus multilocularis	Proteasome, subunit alpha beta	0.0053	0.0644	0.0636
Trypanosoma brucei	proteasome subunit alpha type-5, putative	0.0053	0.0644	0.1489
Toxoplasma gondii	proteasome subunit	0.0053	0.0644	0.1489
Echinococcus multilocularis	proteasome (prosome, macropain) subunit, beta	0.021	0.2806	0.28
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0095	0.1217	0.121
Trypanosoma brucei	Lanosterol 14-alpha demethylase	0.0018	0.0156	0.01
Giardia lamblia	20S proteasome alpha subunit 1	0.0053	0.0644	0.1353
Schistosoma mansoni	ocrl type II inositol 5-phosphatase	0.0019	0.0176	0.0167
Entamoeba histolytica	proteasome subunit alpha type 5, putative	0.0053	0.0644	0.1353
Brugia malayi	Proteasome subunit alpha type 1	0.0053	0.0644	0.0933
Giardia lamblia	20S proteasome alpha subunit 6	0.0053	0.0644	0.1353
Echinococcus granulosus	synaptojanin 1	0.0019	0.0176	0.0167
Entamoeba histolytica	calcium-dependent protein kinase 2, putative	0.0053	0.0644	0.1353
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.013	0.1705	0.4688
Brugia malayi	Uncoordinated protein 44	0.0052	0.0621	0.0897
Plasmodium vivax	proteasome subunit beta type-3, putative	0.0053	0.0644	0.1489
Entamoeba histolytica	proteasome subunit alpha type 4, putative	0.0053	0.0644	0.1353
Trypanosoma cruzi	Inositol phosphosphingolipids phospholipase C	0.0019	0.0176	0.0157
Plasmodium falciparum	DNase I-like protein, putative	0.0019	0.0176	0.0157
Loa Loa (eye worm)	proteasome subunit beta type 3	0.0053	0.0644	0.0931
Echinococcus multilocularis	Proteasome subunit alpha type 7	0.0053	0.0644	0.0636
Trypanosoma brucei	RNA editing exonuclease 2	0.0019	0.0176	0.0157
Brugia malayi	Endonuclease/Exonuclease/phosphatase family protein	0.0019	0.0176	0.022
Trypanosoma brucei	DNA-(apurinic or apyrimidinic site) lyase, putative	0.0019	0.0176	0.0157
Entamoeba histolytica	probable proteasome subunit beta type 2, putative	0.013	0.1705	0.4419
Trypanosoma cruzi	Endonuclease/Exonuclease/phosphatase family, putative	0.0019	0.0176	0.0157
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0053	0.0644	0.1771
Plasmodium falciparum	ATP-dependent protease subunit ClpQ	0.0053	0.0644	0.1489
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0095	0.1217	1
Echinococcus granulosus	Proteasome subunit alpha beta	0.0053	0.0644	0.0636
Brugia malayi	proteasome subunit beta type 3	0.0053	0.0644	0.0933
Trichomonas vaginalis	carbon catabolite repressor protein, putative	0.0019	0.0176	0.0483
Leishmania major	RNA-editing complex protein MP100, putative	0.0019	0.0176	0.0157
Trichomonas vaginalis	carbon catabolite repressor protein, putative	0.0019	0.0176	0.0483
Mycobacterium tuberculosis	Proteasome beta subunit PrcB; assembles with alpha subunit PrcA.	0.0271	0.3637	1
Trypanosoma cruzi	proteasome alpha 7 subunit, putative	0.0053	0.0644	0.1489
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0095	0.1217	0.312
Plasmodium vivax	ATP-dependent protease subunit ClpQ, putative	0.0053	0.0644	0.1489
Schistosoma mansoni	proteasome catalytic subunit 3 (T01 family)	0.0271	0.3637	0.3631
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0053	0.0644	0.1771
Echinococcus multilocularis	endonuclease exonuclease phosphatase	0.0019	0.0176	0.0167
Schistosoma mansoni	synaptojanin	0.0019	0.0176	0.0167
Leishmania major	proteasome alpha 1 subunit, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	mitochondrial protein 99, putative	0.0019	0.0176	0.0157
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0063	0.0772	0.177
Echinococcus multilocularis	netrin receptor unc 5	0.0052	0.0621	0.0613
Leishmania major	20s proteasome beta 7 subunit, (putative)	0.0053	0.0644	0.1489
Giardia lamblia	20S proteasome alpha subunit 3	0.0053	0.0644	0.1353
Plasmodium vivax	proteasome subunit alpha type-7, putative	0.0053	0.0644	0.1489
Trichomonas vaginalis	type II inositol 5-phosphatase, putative	0.0019	0.0176	0.0483
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0063	0.0772	0.177
Loa Loa (eye worm)	jmjC domain-containing protein	0.0058	0.0715	0.1039
Echinococcus granulosus	Proteasome subunit alpha type 7	0.0053	0.0644	0.0636
Brugia malayi	CCR4	0.0019	0.0176	0.022
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0063	0.0772	0.1852
Schistosoma mansoni	cpg binding protein	0.0028	0.03	0.0292
Schistosoma mansoni	subfamily T1A non-peptidase homologue (T01 family)	0.0053	0.0644	0.0636
Loa Loa (eye worm)	proteasome subunit alpha type 2	0.0053	0.0644	0.0931
Trichomonas vaginalis	Family T1, proteasome alpha subunit, threonine peptidase	0.0053	0.0644	0.1771
Toxoplasma gondii	endonuclease/exonuclease/phosphatase family protein	0.0019	0.0176	0.0157
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.013	0.1705	0.1698
Brugia malayi	Death domain containing protein	0.0052	0.0621	0.0897
Plasmodium falciparum	proteasome subunit beta type-2, putative	0.013	0.1705	0.4507
Onchocerca volvulus		0.0028	0.03	0.2663
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0176	0.0218
Trypanosoma cruzi	proteasome beta 6 subunit, putative	0.021	0.2806	0.7637
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0095	0.1217	0.312
Trichomonas vaginalis	ocrl type II inositol 5-phosphatase, putative	0.0019	0.0176	0.0483
Trypanosoma brucei	proteasome beta-1 subunit, putative	0.0053	0.0644	0.1489
Plasmodium falciparum	proteasome subunit alpha type-2, putative	0.0053	0.0644	0.1489
Trypanosoma brucei	cytochrome P450, putative	0.0026	0.0276	0.0442
Brugia malayi	proteasome subunit alpha type 3	0.0053	0.0644	0.0933
Schistosoma mansoni	proteasome subunit beta 1 (T01 family)	0.021	0.2806	0.28
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0053	0.0648	0.1499
Brugia malayi	Proteasome A-type and B-type family protein	0.0271	0.3637	0.5484
Schistosoma mansoni	hypothetical protein	0.0052	0.0621	0.0613
Plasmodium vivax	proteasome subunit beta type-2, putative	0.013	0.1705	0.4507
Schistosoma mansoni	jumonji domain containing protein	0.0057	0.0693	0.0685
Echinococcus granulosus	proteasome subunit beta t family	0.0053	0.0644	0.0636
Leishmania major	proteasome alpha 2 subunit, putative	0.0053	0.0644	0.1489
Trypanosoma cruzi	cytochrome p450-like protein, putative	0.0018	0.0156	0.01
Leishmania major	proteasome beta 2 subunit, putative	0.0053	0.0644	0.1489
Echinococcus granulosus	inositol polyphosphate 5 phosphatase OCRL 1	0.0019	0.0176	0.0167
Plasmodium vivax	proteasome subunit beta type-7, putative	0.0053	0.0644	0.1489
Entamoeba histolytica	proteasome subunit beta Type 4 precursor, putative	0.0053	0.0644	0.1353
Schistosoma mansoni	aldehyde dehydrogenase	0.0063	0.0772	0.0764
Trypanosoma cruzi	cytochrome P450, putative	0.0026	0.0276	0.0442
Entamoeba histolytica	proteasome subunit beta type 1, putative	0.021	0.2806	0.7599
Trypanosoma cruzi	proteasome alpha 2 subunit, putative	0.0053	0.0644	0.1489
Toxoplasma gondii	proteasome subunit beta type 2, putative	0.013	0.1705	0.4507
Echinococcus multilocularis	proteasome subunit beta type 6	0.0053	0.0644	0.0636
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0058	0.0715	0.0708
Trypanosoma brucei	proteasome beta 3 subunit, putative	0.0053	0.0644	0.1489
Plasmodium falciparum	proteasome subunit alpha type-6, putative	0.0053	0.0644	0.1489
Brugia malayi	Protein kinase domain containing protein	0.0052	0.0621	0.0897
Trichomonas vaginalis	Phospholipase C precursor, putative	0.0019	0.0176	0.0483
Echinococcus granulosus	proteasome subunit alpha type 2	0.0053	0.0644	0.0636
Brugia malayi	jmjC domain containing protein	0.0015	0.012	0.0137
Echinococcus granulosus	proteasome prosome macropain subunit beta type	0.0053	0.0644	0.0636
Plasmodium vivax	exodeoxyribonuclease III, putative	0.0019	0.0176	0.0157
Brugia malayi	cytochrome P450	0.0018	0.0156	0.019
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0053	0.0644	0.1771
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0053	0.0644	0.0931
Echinococcus granulosus	neutral sphingomyelinase	0.0019	0.0176	0.0167
Loa Loa (eye worm)	proteasome subunit alpha type 6	0.0053	0.0644	0.0931

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1774434

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1528159