Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0193 | 0.1608 | 0.1608 |
Brugia malayi | Hexokinase family protein | 0.0281 | 0.2641 | 0.2641 |
Trypanosoma brucei | hexokinase | 0.0908 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 2 | 0.0908 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.018 | 0.1459 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0908 | 1 | 1 |
Loa Loa (eye worm) | hexokinase type II | 0.0908 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0211 | 0.1816 | 0.1816 |
Treponema pallidum | hexokinase (hxk) | 0.0908 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.0908 | 1 | 0.5 |
Trypanosoma brucei | hexokinase, putative | 0.0908 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0908 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0908 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.0908 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0908 | 1 | 1 |
Onchocerca volvulus | 0.0908 | 1 | 1 | |
Brugia malayi | Hexokinase family protein | 0.0569 | 0.6029 | 0.6029 |
Brugia malayi | hexokinase type II | 0.0289 | 0.2732 | 0.2732 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.018 | 0.1459 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0193 | 0.1608 | 0.1608 |
Echinococcus multilocularis | hexokinase type 2 | 0.0908 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.0908 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.0908 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0908 | 1 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.0908 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.0908 | 1 | 0.5 |
Plasmodium falciparum | hexokinase | 0.0908 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.0908 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0908 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0289 | 0.2732 | 0.2732 |
Plasmodium vivax | hexokinase, putative | 0.0908 | 1 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0193 | 0.1608 | 0.1608 |
Schistosoma mansoni | hexokinase | 0.0908 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0281 | 0.2641 | 0.2641 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.1309 | 0.1309 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0211 | 0.1816 | 0.1816 |
Trypanosoma brucei | hexokinase | 0.0908 | 1 | 0.5 |
Onchocerca volvulus | 0.0908 | 1 | 1 | |
Onchocerca volvulus | 0.0908 | 1 | 1 | |
Trypanosoma cruzi | hexokinase, putative | 0.0908 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0289 | 0.2732 | 0.2732 |
Echinococcus multilocularis | hexokinase | 0.0908 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0569 | 0.6029 | 0.6029 |
Loa Loa (eye worm) | hypothetical protein | 0.0619 | 0.6612 | 0.6612 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0193 | 0.1608 | 0.1608 |
Leishmania major | hexokinase, putative | 0.0908 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.