Detailed information for compound 1529738

Basic information

Technical information
  • TDR Targets ID: 1529738
  • Name: 3-methoxy-N,N-dimethyl-4-[(Z)-(1-methyl-2-phe nylpyrazolo[1,5-a]indol-1-ium-4-ylidene)methy l]aniline; trifluoromethanesulfonate
  • MW: 557.584 | Formula: C28H26F3N3O4S
  • H donors: 1 H acceptors: 3 LogP: 6.31 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: FC(S(=O)(=O)[O-])(F)F.COc1cc(ccc1C=c1c2ccccc2n2c1cc([n+]2C)c1ccccc1)N(C)C
  • InChi: 1S/C27H26N3O.CHF3O3S/c1-28(2)21-15-14-20(27(17-21)31-4)16-23-22-12-8-9-13-24(22)30-26(23)18-25(29(30)3)19-10-6-5-7-11-19;2-1(3,4)8(5,6)7/h5-18H,1-4H3;(H,5,6,7)/q+1;/p-1
  • InChiKey: OTUQBJVZQSQBAC-UHFFFAOYSA-M  


Substructure search Similarity search

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Synonyms

  • 3-methoxy-N,N-dimethyl-4-[(Z)-(1-methyl-2-phenyl-pyrazolo[1,5-a]indol-1-ium-4-ylidene)methyl]aniline; trifluoromethanesulfonate
  • 3-methoxy-N,N-dimethyl-4-[(Z)-(1-methyl-2-phenyl-4-pyrazolo[1,5-a]indol-1-iumylidene)methyl]aniline; trifluoromethanesulfonate
  • [3-methoxy-4-[(Z)-(1-methyl-2-phenyl-pyrazolo[1,5-a]indol-1-ium-4-ylidene)methyl]phenyl]-dimethyl-amine; trifluoromethanesulfonate
  • NSC699476

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Plasmodium berghei glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Plasmodium falciparum heat shock protein 90, putative Starlite/ChEMBL No references
Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Homo sapiens Wolf-Hirschhorn syndrome candidate 1 Starlite/ChEMBL No references
Bos taurus Thrombin Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Human immunodeficiency virus 1 Aberrant vpr protein Starlite/ChEMBL No references
Homo sapiens matrix metallopeptidase 14 (membrane-inserted) Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens flap structure-specific endonuclease 1 Starlite/ChEMBL No references
Homo sapiens nuclear receptor subfamily 2, group F, member 1 Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references
Homo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog Starlite/ChEMBL No references
Homo sapiens RAN, member RAS oncogene family No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum expressed protein Get druggable targets OG5_130029 All targets in OG5_130029
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Giardia lamblia Flap structure-specific endonuclease Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K07996 matrix metalloproteinase-16 (membrane-inserted), putative Get druggable targets OG5_129064 All targets in OG5_129064
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Entamoeba histolytica Flap nuclease, putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K04799 flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Loa Loa (eye worm) heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K04079 molecular chaperone HtpG, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) nuclear hormone receptor Get druggable targets OG5_131829 All targets in OG5_131829
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Babesia bovis hsp90 protein Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum ko:K09435 transcriptional regulator ERG, putative Get druggable targets OG5_131947 All targets in OG5_131947
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii Glucose-6-phosphate dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Brugia malayi Flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii flap structure-specific endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock 90 kDa protein homolog Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K05302 histone-lysine N-methyltransferase [EC2.1.1.43], putative Get druggable targets OG5_130029 All targets in OG5_130029
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49), related Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma brucei gambiense glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Echinococcus granulosus flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium berghei flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Babesia bovis XPG N-terminal domain and XPG I-region domain containing protein Get druggable targets OG5_127472 All targets in OG5_127472
Cryptosporidium parvum flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Cryptosporidium hominis heat shock protein 83 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia Grp94/Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania infantum flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49), related Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129064 All targets in OG5_129064
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni SET domain protein Get druggable targets OG5_130029 All targets in OG5_130029
Schistosoma mansoni flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus granulosus endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor Get druggable targets OG5_131829 All targets in OG5_131829
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor Get druggable targets OG5_131829 All targets in OG5_131829
Leishmania major flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium knowlesi glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Candida albicans likely glucose-6-phosphate dehydrogenase similar to S. cerevisiae ZWF1 (YNL241C) Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma cruzi Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09487 heat shock protein 90kDa beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum protein with 4 PHD domains plus a SET domain and associated cysteine cluster at the C-terminus Get druggable targets OG5_130029 All targets in OG5_130029
Leishmania donovani glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Onchocerca volvulus Matrilysin homolog Get druggable targets OG5_129064 All targets in OG5_129064
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii putative heat shock protein 81-2 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131829 All targets in OG5_131829
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) Get druggable targets OG5_129064 All targets in OG5_129064
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax heat shock protein 86, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii Hsp90 domain-containing protein Get druggable targets OG5_144951 All targets in OG5_144951
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania mexicana lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Trypanosoma brucei gambiense flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii flap endonuclease-1-related Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma congolense flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Cryptosporidium hominis flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni ets-related Get druggable targets OG5_131947 All targets in OG5_131947
Trypanosoma brucei gambiense heat shock protein 83,heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum HSP90, related Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein heat shock protein 90 alpha Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Treponema pallidum glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans likely glucose-6-phosphate dehydrogenase similar to S. cerevisiae ZWF1 (YNL241C) Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis histone lysine N methyltransferase NSD3 Get druggable targets OG5_130029 All targets in OG5_130029
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Fli-1 protein Get druggable targets OG5_131947 All targets in OG5_131947
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum HSP90-like protein, related Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Heat shock protein HSP 90-alpha, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Matrixin family protein Get druggable targets OG5_129064 All targets in OG5_129064
Babesia bovis heat shock protein 90 Get druggable targets OG5_144951 All targets in OG5_144951
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii heat shock protein HSP90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum IPR002477,Peptidoglycan-binding domain 1;IPR009070,Peptidoglycan binding-like,domain-containing Get druggable targets OG5_129064 All targets in OG5_129064
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium knowlesi endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Endoplasmin precursor Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) Get druggable targets OG5_129064 All targets in OG5_129064
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Histone-lysine N-methyltransferase NSD3, putative Get druggable targets OG5_130029 All targets in OG5_130029
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus histone lysine N methyltransferase NSD3 Get druggable targets OG5_130029 All targets in OG5_130029
Plasmodium vivax heat shock protein, putative Get druggable targets OG5_144951 All targets in OG5_144951
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus multilocularis flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania donovani heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus matrix metallopeptidase 7 M10 family Get druggable targets OG5_129064 All targets in OG5_129064
Loa Loa (eye worm) fli-1 protein Get druggable targets OG5_131947 All targets in OG5_131947
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) matrixin family protein Get druggable targets OG5_129064 All targets in OG5_129064
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis 6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania donovani flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Schistosoma japonicum ko:K00036 glucose-6-phosphate 1-dehydrogenase [EC1.1.1.49], putative Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Treponema pallidum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock protein 83 Get druggable targets OG5_144951 All targets in OG5_144951
Theileria parva heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_130029 All targets in OG5_130029
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans hypothetical protein Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Steroid receptor seven-up type 2 Get druggable targets OG5_131829 All targets in OG5_131829
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Trypanosoma brucei exonuclease, putative flap structure-specific endonuclease 1 380 aa 322 aa 24.5 %
Brugia malayi ecdysteroid receptor nuclear receptor subfamily 2, group F, member 1 423 aa 354 aa 26.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0099 0.2399 0.2382
Brugia malayi Endoplasmin precursor 0.0055 0.1184 0.1682
Giardia lamblia Grp94/Hsp90 0.0052 0.1089 0.2882
Schistosoma mansoni alpha-1 adrenergic receptor 0.0099 0.2399 0.2399
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0292 0.073
Brugia malayi Hsp90 protein 0.0037 0.0667 0.0947
Echinococcus granulosus alpha 1A adrenergic receptor 0.0099 0.2399 0.2382
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0356 0.1044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0613 0.0446
Loa Loa (eye worm) pigment dispersing factor receptor c 0.012 0.2997 0.2873
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Onchocerca volvulus 0.0099 0.2399 0.6917
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0099 0.2399 0.3408
Echinococcus multilocularis somatostatin receptor 0.0099 0.2399 0.2382
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0539 0.1557
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0613 0.1991
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0123 0.3059 0.5432
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0052 0.1089 0.5
Brugia malayi neuropeptide F receptor 0.0099 0.2399 0.3408
Trichomonas vaginalis heat shock protein, putative 0.0055 0.1184 0.3719
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0099 0.2399 0.2382
Echinococcus granulosus dna polymerase kappa 0.0023 0.0292 0.027
Schistosoma mansoni hypothetical protein 0.0372 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus granulosus heat shock protein 90 0.0047 0.0961 0.0941
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0292 0.073
Echinococcus multilocularis neuropeptide Y receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0082 0.1936 0.1793
Schistosoma mansoni jumonji domain containing protein 0.0092 0.2195 0.2195
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0099 0.2399 0.2382
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus multilocularis neuropeptide FF receptor 2 0.0099 0.2399 0.2382
Trypanosoma brucei unspecified product 0.0016 0.009 0.006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Schistosoma mansoni endoplasmin 0.0055 0.1184 0.1184
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Schistosoma mansoni opsin-like receptor 0.0099 0.2399 0.2399
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.009 0.006
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0121 0.3007 0.2991
Schistosoma mansoni hypothetical protein 0.0035 0.0623 0.0623
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0038 0.0704 0.0683
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0099 0.2399 0.3408
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0037 0.0667 0.0645
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Brugia malayi Latrophilin receptor protein 2 0.0038 0.0704 0.1
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0164 0.4198 0.4185
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0099 0.2399 0.2382
Brugia malayi Fli-1 protein 0.0265 0.704 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0099 0.2399 0.2382
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0113 0.278 1
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0123 0.3059 1
Schistosoma mansoni hypothetical protein 0.0099 0.2399 0.2399
Brugia malayi Flap endonuclease-1 0.0031 0.0519 0.0737
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0623 0.0457
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0099 0.2399 0.2399
Schistosoma mansoni amine GPCR 0.0099 0.2399 0.2399
Leishmania major heat shock protein, putative 0.0037 0.0667 0.219
Schistosoma mansoni hypothetical protein 0.0205 0.5344 0.5344
Brugia malayi Kringle domain containing protein 0.0021 0.0235 0.0334
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0961 0.2973
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0519 0.1643
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0519 0.0649
Echinococcus multilocularis heat shock protein 0.0055 0.1184 0.1164
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0519 0.149
Echinococcus granulosus neuropeptide receptor 0.0099 0.2399 0.2382
Echinococcus multilocularis snurportin 1 0.0372 1 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0356 0.0234
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0961 0.328
Schistosoma mansoni biogenic amine (5HT) receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni neuropeptide F-like receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Onchocerca volvulus 0.0099 0.2399 0.6917
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.083 0.0809
Toxoplasma gondii kringle domain-containing protein 0.0021 0.0235 0.0115
Echinococcus granulosus bloom syndrome protein 0.0029 0.045 0.0428
Schistosoma mansoni hypothetical protein 0.0038 0.0704 0.0704
Brugia malayi larval opioid receptor 0.0099 0.2399 0.3408
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0292 0.027
Loa Loa (eye worm) hypothetical protein 0.006 0.1324 0.1171
Plasmodium falciparum heat shock protein 90 0.0055 0.1184 0.1902
Echinococcus granulosus 7TM GPCR rhodopsin 0.0099 0.2399 0.2382
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0174 0.0152
Loa Loa (eye worm) hypothetical protein 0.0021 0.0229 0.0056
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0047 0.0961 0.0941
Brugia malayi latrophilin 2 splice variant baaae 0.0082 0.1936 0.275
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0853 0.0832
Schistosoma mansoni hypothetical protein 0.0043 0.0853 0.0853
Onchocerca volvulus 0.0099 0.2399 0.6917
Echinococcus multilocularis neuropeptides capa receptor 0.0099 0.2399 0.2382
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0174 0.0152
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus granulosus biogenic amine 5HT receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Brugia malayi glucose-6-phosphate dehydrogenase 0.0113 0.278 0.3949
Trypanosoma cruzi Heat shock protein 83, putative 0.0055 0.1184 0.4103
Schistosoma mansoni neuropeptide F-like receptor 0.0099 0.2399 0.2399
Schistosoma mansoni biogenic amine receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0174 0.037
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.0519 0.082
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0099 0.2399 0.3408
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Onchocerca volvulus 0.003 0.0474 0.0781
Onchocerca volvulus 0.0099 0.2399 0.6917
Brugia malayi jmjC domain containing protein 0.0043 0.083 0.1179
Onchocerca volvulus Neuropeptide F receptor homolog 0.0099 0.2399 0.6917
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0074 0.1692 0.5626
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Brugia malayi hypothetical protein 0.003 0.0491 0.0697
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.0352 0.0335
Trypanosoma cruzi heat shock protein 90, putative 0.0055 0.1184 0.4103
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus multilocularis serotonin receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0853 0.0832
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni hypothetical protein 0.0038 0.0704 0.0704
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.0539 0.0686
Toxoplasma gondii heat shock protein 90, putative 0.0055 0.1184 0.1902
Brugia malayi Bromodomain containing protein 0.0035 0.0623 0.0885
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0164 0.4198 0.4185
Echinococcus granulosus tm gpcr rhodopsin 0.0099 0.2399 0.2382
Schistosoma mansoni hypothetical protein 0.0014 0.0023 0.0023
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0174 0.0152
Echinococcus granulosus g protein coupled receptor 0.0099 0.2399 0.2382
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0099 0.2399 0.2382
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0113 0.278 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0099 0.2399 0.2399
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) neuropeptide F receptor 0.0099 0.2399 0.2265
Brugia malayi Dopamine receptor protein 1 0.0099 0.2399 0.3408
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0174 0.0174
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0174 0.037
Plasmodium falciparum heat shock protein 90, putative 0.021 0.5486 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0038 0.0704 0.0683
Mycobacterium ulcerans heat shock protein 90 0.0052 0.1089 0.3206
Echinococcus granulosus tissue type plasminogen activator 0.0021 0.0235 0.0213
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0099 0.2399 0.2382
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Echinococcus multilocularis g protein coupled receptor 0.0099 0.2399 0.2382
Schistosoma mansoni hypothetical protein 0.0099 0.2399 0.2399
Schistosoma mansoni ran 0.0026 0.0356 0.0356
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0099 0.2399 0.2382
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0174 0.0152
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.1184 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0099 0.2399 0.2399
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0292 0.0805
Onchocerca volvulus 0.0099 0.2399 0.6917
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Schistosoma mansoni hypothetical protein 0.0099 0.2399 0.2399
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0113 0.278 0.2764
Echinococcus multilocularis allatostatin A receptor 0.0099 0.2399 0.2382
Onchocerca volvulus Alhambra homolog 0.0035 0.0623 0.1257
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0123 0.3059 0.5432
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0099 0.2399 0.2382
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Plasmodium falciparum phd finger protein, putative 0.0035 0.0623 0.0846
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0099 0.2399 0.2382
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0357 0.0507
Echinococcus granulosus fmrfamide receptor 0.0099 0.2399 0.2382
Trichomonas vaginalis DNA helicase recq1, putative 0.0029 0.045 0.126
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0099 0.2399 0.2382
Echinococcus granulosus G protein coupled receptor 139 0.0099 0.2399 0.2382
Schistosoma mansoni biogenic amine (5HT) receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Plasmodium falciparum importin beta, putative 0.0035 0.0613 0.0826
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Schistosoma mansoni myosin xvIII 0.0099 0.2399 0.2399
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0429 0.119
Echinococcus granulosus peptide allatostatin:somatostatin 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.003 0.0491 0.0322
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0491 0.0596
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Loa Loa (eye worm) hypothetical protein 0.0115 0.2846 0.2719
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Schistosoma mansoni histamine h1 receptor 0.0099 0.2399 0.2399
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.1184 1
Trichomonas vaginalis heat shock protein, putative 0.0052 0.1089 0.3402
Brugia malayi Ets-domain containing protein 0.0087 0.2079 0.2953
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0235 0.0596
Plasmodium falciparum flap endonuclease 1 0.0031 0.0519 0.0649
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0623 0.0846
Onchocerca volvulus 0.0099 0.2399 0.6917
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Echinococcus multilocularis neuropeptide Y receptor 0.0099 0.2399 0.2382
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.2855 0.2839
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0292 0.1286
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0356 0.1044
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0099 0.2399 0.3408
Leishmania major DNA polymerase eta, putative 0.0023 0.0292 0.0805
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Loa Loa (eye worm) matrixin family protein 0.0047 0.0943 0.0783
Brugia malayi G protein-coupled receptor 0.0099 0.2399 0.3408
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.009 0.006
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0099 0.2399 0.2382
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.1668 0.152
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0491 0.0596
Echinococcus granulosus serotonin receptor 0.0099 0.2399 0.2382
Plasmodium falciparum endoplasmin, putative 0.004 0.0761 0.1106
Loa Loa (eye worm) hypothetical protein 0.0021 0.0235 0.0062
Echinococcus granulosus somatostatin receptor 0.0099 0.2399 0.2382
Brugia malayi isocitrate dehydrogenase 0.0019 0.0174 0.0247
Echinococcus multilocularis orexin receptor type 2 0.0099 0.2399 0.2382
Schistosoma mansoni neuropeptide f receptor 76f 0.0099 0.2399 0.2399
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0292 0.0414
Onchocerca volvulus Matrix metalloproteinase homolog 0.0047 0.0943 0.2277
Loa Loa (eye worm) nuclear hormone receptor 0.0114 0.2827 0.27
Loa Loa (eye worm) hypothetical protein 0.0146 0.3708 0.3597
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0037 0.0667 0.5339
Schistosoma mansoni amine GPCR 0.0099 0.2399 0.2399
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0356 0.0186
Brugia malayi MH2 domain containing protein 0.0144 0.3659 0.5198
Schistosoma mansoni hypothetical protein 0.0205 0.5344 0.5344
Echinococcus multilocularis neuropeptide receptor 0.0099 0.2399 0.2382
Trypanosoma brucei Heat shock protein 83, putative 0.0055 0.1184 0.4103
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0038 0.0704 0.0683
Echinococcus granulosus GPCR family 2 0.0038 0.0704 0.0683
Brugia malayi putative neuropeptide receptor NPR1 0.0099 0.2399 0.3408
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus multilocularis G protein coupled receptor 139 0.0099 0.2399 0.2382
Loa Loa (eye worm) neuropeptide F receptor 0.0099 0.2399 0.2265
Trypanosoma cruzi heat shock protein, putative 0.0037 0.0667 0.219
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.083 0.083
Echinococcus multilocularis geminin 0.0205 0.5344 0.5333
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0292 0.1962
Echinococcus granulosus allatostatin A receptor 0.0099 0.2399 0.2382
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.1184 0.4103
Echinococcus multilocularis endoplasmin 0.0052 0.1089 0.1069
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0108 0.2652 0.2652
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Schistosoma mansoni adenoreceptor 0.0099 0.2399 0.2399
Entamoeba histolytica hypothetical protein 0.0028 0.0429 0.3199
Brugia malayi Bloom's syndrome protein homolog 0.0029 0.045 0.0639
Brugia malayi follicle stimulating hormone receptor 0.0099 0.2399 0.3408
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni hypothetical protein 0.0038 0.0704 0.0704
Echinococcus granulosus sex peptide receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0039 0.0731 0.6082
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni opsin-like receptor 0.0099 0.2399 0.2399
Brugia malayi hypothetical protein 0.002 0.019 0.027
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0099 0.2399 0.2382
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0292 0.027
Echinococcus granulosus neuropeptide Y receptor 0.0099 0.2399 0.2382
Leishmania major DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Onchocerca volvulus 0.0099 0.2399 0.6917
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.3659 0.3547
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.1184 0.4103
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Schistosoma mansoni biogenic amine receptor 0.0099 0.2399 0.2399
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0113 0.278 0.2764
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni heat shock protein 0.0055 0.1184 0.1184
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Echinococcus granulosus tm gpcr rhodopsin 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0035 0.0623 0.0457
Plasmodium vivax heat shock protein 86, putative 0.0055 0.1184 0.1902
Brugia malayi PHD-finger family protein 0.0035 0.0623 0.0885
Entamoeba histolytica Ran family GTPase 0.0026 0.0356 0.2545
Leishmania major GTP-binding protein, putative 0.0026 0.0356 0.1044
Loa Loa (eye worm) TK/ROR protein kinase 0.0021 0.0235 0.0062
Echinococcus granulosus peregrin 0.0047 0.0944 0.0923
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.004 0.0745 0.0724
Schistosoma mansoni hypothetical protein 0.0038 0.0704 0.0704
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0099 0.2399 0.2265
Brugia malayi hypothetical protein 0.0043 0.0853 0.1212
Brugia malayi G-protein coupled receptor 0.0099 0.2399 0.3408
Onchocerca volvulus Matrilysin homolog 0.0134 0.3366 1
Echinococcus granulosus neuropeptide s receptor 0.0099 0.2399 0.2382
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.0357 0.1997
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.083 0.083
Onchocerca volvulus 0.0099 0.2399 0.6917
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0356 0.0334
Echinococcus multilocularis heat shock protein 90 0.0047 0.0961 0.0941
Brugia malayi Matrixin family protein 0.0021 0.0229 0.0325
Brugia malayi RE15519p 0.0099 0.2399 0.3408
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0292 0.1286
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0961 0.242
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0429 0.119
Brugia malayi Hemopexin family protein 0.003 0.0474 0.0674
Schistosoma mansoni ran 0.0026 0.0356 0.0356
Loa Loa (eye worm) TYRA-2 protein 0.0099 0.2399 0.2265
Schistosoma mansoni neuropeptide receptor 0.0099 0.2399 0.2399
Schistosoma mansoni heat shock protein 0.0037 0.0667 0.0667
Brugia malayi Tachykinin-like peptides receptor 99D 0.0099 0.2399 0.3408
Toxoplasma gondii heat shock protein 75, putative 0.0037 0.0667 0.0928
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0429 0.119
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0099 0.2399 0.2382
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0491 0.154
Brugia malayi neuropeptide F receptor 0.0099 0.2399 0.3408
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0037 0.0682 0.2247
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0292 0.0805
Brugia malayi heat shock protein 90 0.0055 0.1184 0.1682
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.3659 0.3547
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0174 0.0247
Schistosoma mansoni growth hormone secretagogue receptor 0.0099 0.2399 0.2399
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0623 0.0602
Echinococcus granulosus g-protein coupled receptor 0.0099 0.2399 0.2382
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0519 0.1643
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0037 0.0667 0.0645
Echinococcus multilocularis g protein coupled receptor 0.0099 0.2399 0.2382
Brugia malayi Melatonin receptor type 1A 0.0099 0.2399 0.3408
Loa Loa (eye worm) hypothetical protein 0.0026 0.0357 0.0186
Echinococcus granulosus flap endonuclease 1 0.0031 0.0519 0.0497
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0099 0.2399 0.2382
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0292 0.0805
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.1008 0.0987
Loa Loa (eye worm) matrix metalloproteinase 0.0021 0.0229 0.0056
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.083 0.0667
Loa Loa (eye worm) heat shock protein 75 0.0037 0.0667 0.0501
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0623 0.0602
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0182 0.0015
Echinococcus multilocularis G-protein coupled receptor, putative 0.0099 0.2399 0.2382
Loa Loa (eye worm) matrixin family protein 0.0138 0.3484 0.3368
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0099 0.2399 0.2265
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Schistosoma mansoni amine GPCR 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni hypothetical protein 0.0082 0.1936 0.1936
Plasmodium vivax heat shock protein 90, putative 0.0037 0.0667 0.0928
Plasmodium falciparum cysteine repeat modular protein 1 0.0021 0.0235 0.0115
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0038 0.0704 0.0683
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Schistosoma mansoni gabp alpha 0.0087 0.2079 0.2079
Loa Loa (eye worm) hypothetical protein 0.0023 0.0292 0.012
Echinococcus granulosus jumonji domain containing protein 0.0049 0.1008 0.0987
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0087 0.2079 0.1939
Onchocerca volvulus 0.0099 0.2399 0.6917
Echinococcus granulosus hypothetical protein 0.0099 0.2399 0.2382
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0099 0.2399 0.2265
Onchocerca volvulus 0.0099 0.2399 0.6917
Schistosoma mansoni SET domain protein 0.004 0.0745 0.0745
Echinococcus multilocularis peregrin 0.0047 0.0944 0.0923
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0099 0.2399 0.2382
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0123 0.3059 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0174 0.037
Onchocerca volvulus 0.0021 0.0235 0.002
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0036 0.0652 0.2136
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0038 0.0704 0.1
Schistosoma mansoni biogenic amine receptor 0.0099 0.2399 0.2399
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0099 0.2399 0.2399
Plasmodium vivax endoplasmin, putative 0.0055 0.1184 0.1902
Echinococcus granulosus 7tm_1 domain containing protein 0.0099 0.2399 0.2382
Echinococcus multilocularis g protein coupled receptor 0.0099 0.2399 0.2382
Schistosoma mansoni opsin-like receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Brugia malayi Serotonin receptor 0.0099 0.2399 0.3408
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.1184 0.4103
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0123 0.3059 0.5432
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus granulosus neuropeptide Y receptor 0.0099 0.2399 0.2382
Trypanosoma brucei unspecified product 0.0023 0.0292 0.0805
Schistosoma mansoni amine GPCR 0.0099 0.2399 0.2399
Brugia malayi Calcitonin receptor-like protein seb-1 0.012 0.2997 0.4257
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0099 0.2399 0.2399
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.012 0.2997 0.4257
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Echinococcus multilocularis g-protein coupled receptor 0.0099 0.2399 0.2382
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0099 0.2399 0.2399
Echinococcus granulosus heat shock protein 0.0055 0.1184 0.1164
Brugia malayi Serotonin receptor 0.0099 0.2399 0.3408
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0174 0.0152
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0429 0.1313
Echinococcus granulosus endoplasmin 0.0052 0.1089 0.1069
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0121 0.3007 0.2991
Brugia malayi AKH receptor 0.0099 0.2399 0.3408
Plasmodium vivax importin-beta 2, putative 0.0035 0.0613 0.0826
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0113 0.278 0.278
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0174 0.037
Loa Loa (eye worm) fli-1 protein 0.0265 0.704 0.6988
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0356 0.0344
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0491 0.154
Brugia malayi Matrixin family protein 0.0021 0.0229 0.0325
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.083 0.0809
Echinococcus multilocularis heat shock protein 90 0.0055 0.1184 0.1164
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Leishmania major hypothetical protein, conserved 0.003 0.0491 0.154
Echinococcus multilocularis GPCR, family 2 0.0038 0.0704 0.0683
Brugia malayi Dopamine receptor 0.0099 0.2399 0.3408
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0519 0.0497
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.2855 0.2839
Echinococcus multilocularis neuropeptide receptor 0.0099 0.2399 0.2382
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0099 0.2399 0.2382
Echinococcus granulosus heat shock protein 90 0.0055 0.1184 0.1164
Loa Loa (eye worm) hypothetical protein 0.012 0.2997 0.2873
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0623 0.0846
Echinococcus granulosus neuropeptides capa receptor 0.0099 0.2399 0.2382
Trichomonas vaginalis heat shock protein, putative 0.0052 0.1089 0.3402
Brugia malayi Dopamine receptor protein 2 0.0099 0.2399 0.3408
Trypanosoma brucei heat shock protein 84, putative 0.0037 0.0667 0.219
Schistosoma mansoni importin beta-1 0.0035 0.0613 0.0613
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Schistosoma mansoni amine GPCR 0.0099 0.2399 0.2399
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0099 0.2399 0.2399
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0491 0.0596
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0052 0.1089 1
Echinococcus granulosus neuropeptide receptor 0.0099 0.2399 0.2382
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0356 0.1044
Echinococcus multilocularis bloom syndrome protein 0.0029 0.045 0.0428
Echinococcus granulosus neuropeptide FF receptor 2 0.0099 0.2399 0.2382
Schistosoma mansoni heat shock protein 0.0055 0.1184 0.1184
Echinococcus multilocularis sex peptide receptor 0.0099 0.2399 0.2382
Echinococcus multilocularis dro:myosuppressin receptor 0.0099 0.2399 0.2382
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0021 0.0235 0.0115
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0174 0.037
Loa Loa (eye worm) heat shock protein 90 0.0055 0.1184 0.1028
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0519 0.4006
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0292 0.0414
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0623 0.0623
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0491 0.0596
Brugia malayi Matrixin family protein 0.0138 0.3484 0.4948
Echinococcus granulosus importin subunit beta 1 0.0035 0.0613 0.0591
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0052 0.1089 0.3753
Trichomonas vaginalis ran, putative 0.0026 0.0356 0.0946
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0099 0.2399 0.2399
Entamoeba histolytica hypothetical protein 0.0043 0.0853 0.7017
Plasmodium vivax heat shock protein, putative 0.021 0.5486 1
Echinococcus multilocularis neuropeptide receptor A26 0.0099 0.2399 0.2382
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0961 0.328
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0519 0.1643
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0113 0.278 0.2652
Schistosoma mansoni hypothetical protein 0.0021 0.0235 0.0235
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.1184 0.4103
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0292 0.0292
Schistosoma mansoni flap endonuclease-1 0.0028 0.0434 0.0434
Leishmania major importin beta-1 subunit, putative 0.0028 0.0429 0.1313
Schistosoma mansoni neuropeptide receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) G-protein coupled receptor 0.0099 0.2399 0.2265
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Echinococcus granulosus tm gpcr rhodopsin 0.0099 0.2399 0.2382
Loa Loa (eye worm) latrophilin receptor protein 2 0.0038 0.0704 0.0539
Echinococcus granulosus orexin receptor type 2 0.0099 0.2399 0.2382
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.002 0.0189 0.0027
Echinococcus granulosus GA binding protein alpha chain 0.0087 0.2079 0.2061
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0099 0.2399 0.2382
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Loa Loa (eye worm) melatonin receptor type 1A 0.0099 0.2399 0.2265
Echinococcus multilocularis serotonin receptor 0.0099 0.2399 0.2382
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0099 0.2399 0.3408
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Onchocerca volvulus 0.0099 0.2399 0.6917
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0113 0.278 1
Onchocerca volvulus 0.0099 0.2399 0.6917
Brugia malayi Matrixin family protein 0.0021 0.0229 0.0325
Entamoeba histolytica hypothetical protein 0.0043 0.0853 0.7017
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0356 0.0506
Brugia malayi GnHR receptor homolog 0.0099 0.2399 0.3408
Brugia malayi Ets-domain containing protein 0.0087 0.2079 0.2953
Brugia malayi Protein kinase domain containing protein 0.0021 0.0235 0.0334
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0099 0.2399 0.2399
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.028 0.028
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.0288 0.0791
Echinococcus multilocularis neuropeptide s receptor 0.0099 0.2399 0.2382
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.009 0.006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Brugia malayi Matrixin family protein 0.0021 0.0229 0.0325
Brugia malayi Steroid receptor seven-up type 2 0.0121 0.3007 0.4271
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Schistosoma mansoni hypothetical protein 0.0099 0.2399 0.2399
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0613 0.1991
Brugia malayi RNA, U transporter 1 0.0099 0.2401 0.3411
Echinococcus granulosus g protein coupled receptor 0.0099 0.2399 0.2382
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Mycobacterium ulcerans hydrolase 0.0026 0.0357 0.0262
Onchocerca volvulus 0.0099 0.2399 0.6917
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0108 0.2652 0.2522
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0123 0.3059 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0099 0.2399 0.2265
Loa Loa (eye worm) hypothetical protein 0.0038 0.0704 0.0539
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Echinococcus granulosus tachykinin peptides receptor 99D 0.0099 0.2399 0.2382
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Brugia malayi ORL1-like opioid receptor 0.0099 0.2399 0.3408
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0292 0.0805
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0356 0.0344
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Echinococcus granulosus dna polymerase eta 0.0023 0.0292 0.027
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Leishmania major hypothetical protein, conserved 0.0021 0.0235 0.0596
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0099 0.2399 0.2399
Brugia malayi sulfakinin receptor protein 0.0099 0.2399 0.3408
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0519 0.0649
Echinococcus multilocularis dna polymerase eta 0.0023 0.0292 0.027
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Schistosoma mansoni ets-related 0.0265 0.704 0.704
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0174 0.0152
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0113 0.278 1
Schistosoma mansoni hypothetical protein 0.003 0.0474 0.0474
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0292 0.0805
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0052 0.1089 1
Onchocerca volvulus 0.0099 0.2399 0.6917
Brugia malayi putative neuropeptide receptor 0.0099 0.2399 0.3408
Echinococcus multilocularis neuropeptides capa receptor 0.0099 0.2399 0.2382
Entamoeba histolytica hypothetical protein 0.0043 0.0853 0.7017
Echinococcus granulosus g protein coupled receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Toxoplasma gondii Hsp90 domain-containing protein 0.021 0.5486 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0356 0.0344
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Schistosoma mansoni neuropeptide receptor 0.0099 0.2399 0.2399
Schistosoma mansoni neuropeptide receptor 0.0099 0.2399 0.2399
Loa Loa (eye worm) endoplasmin 0.0055 0.1184 0.1028
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.045 0.126
Echinococcus multilocularis GA binding protein alpha chain 0.0087 0.2079 0.2061
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0613 0.0826
Brugia malayi G protein-coupled receptor F59B2.13 0.0099 0.2399 0.3408
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0113 0.278 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0099 0.2399 0.2399
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.2399 0.2399
Onchocerca volvulus 0.0099 0.2399 0.6917
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0113 0.278 1
Toxoplasma gondii heat shock protein HSP90 0.0055 0.1184 0.1902
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Onchocerca volvulus 0.0099 0.2399 0.6917
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0356 0.0334
Giardia lamblia PHD finger protein 15 0.0035 0.0623 0.1198
Loa Loa (eye worm) RecQ helicase 0.0029 0.045 0.0281
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Trichomonas vaginalis heat shock protein, putative 0.004 0.0761 0.2303
Trichomonas vaginalis endoplasmin, putative 0.004 0.0761 0.2303
Loa Loa (eye worm) G-protein coupled receptor 0.0099 0.2399 0.2265
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.004 0.0745 0.0724
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0229 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0292 0.0805
Trypanosoma brucei heat shock protein, putative 0.0055 0.1184 0.4103
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Trypanosoma brucei unspecified product 0.0016 0.009 0.006
Loa Loa (eye worm) hypothetical protein 0.0075 0.1726 0.1579
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0853 0.0853
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.2399 0.2382
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0292 0.012
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0519 0.0351
Echinococcus granulosus neuropeptide receptor A26 0.0099 0.2399 0.2382
Echinococcus multilocularis fmrfamide receptor 0.0099 0.2399 0.2382
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0099 0.2399 0.6917
Echinococcus granulosus biogenic amine 5HT receptor 0.0099 0.2399 0.2382
Schistosoma mansoni DNA polymerase eta 0.0023 0.0292 0.0292
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0613 0.0591
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.1184 0.4103
Brugia malayi jmjC domain containing protein 0.0115 0.2855 0.4056
Brugia malayi Importin beta-1 subunit 0.0035 0.0613 0.087
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0074 0.1692 0.2857
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0292 0.027
Brugia malayi G-protein coupled receptor 0.0099 0.2399 0.3408
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0037 0.0667 0.1395
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0623 0.0846
Echinococcus multilocularis tissue type plasminogen activator 0.0021 0.0235 0.0213
Brugia malayi hypothetical protein 0.0099 0.2399 0.3408
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0292 0.0805
Echinococcus granulosus dro:myosuppressin receptor 0.0099 0.2399 0.2382
Echinococcus granulosus geminin 0.0205 0.5344 0.5333
Entamoeba histolytica hypothetical protein 0.0043 0.0853 0.7017
Echinococcus granulosus neuropeptides capa receptor 0.0099 0.2399 0.2382
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0099 0.2399 0.2265
Loa Loa (eye worm) hypothetical protein 0.0099 0.2399 0.2265
Giardia lamblia Heat shock protein HSP 90-alpha 0.0055 0.1184 0.3224
Echinococcus multilocularis fmrfamide receptor 0.0099 0.2399 0.2382
Leishmania major heat shock protein 83-1 0.0055 0.1184 0.4103
Schistosoma mansoni endoplasmin 0.0055 0.1184 0.1184
Onchocerca volvulus 0.0099 0.2399 0.6917
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0123 0.3059 1
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0491 0.154

Activities

Activity type Activity value Assay description Source Reference
AC50 (binding) 3.07 uM PubChem BioAssay. Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
AC50 (functional) = 7.549 uM PUBCHEM_BIOASSAY: Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] ChEMBL. No reference
AC50 (functional) = 7.598 uM PUBCHEM_BIOASSAY: HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] ChEMBL. No reference
AC50 (binding) = 39.938 uM PUBCHEM_BIOASSAY: Fluorescence Polarization with Cer CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504435] ChEMBL. No reference
EC50 (functional) 20 uM PUBCHEM_BIOASSAY: High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, compounds from Cherry Pick 02. (Class of assay: confirmatory) ChEMBL. No reference
EC50 (functional) 20 uM PUBCHEM_BIOASSAY: High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Lethal Factor protease, compounds from Cherry Pick 02. (Class of assay: confirmatory) ChEMBL. No reference
EC50 (functional) 20 uM PubChem BioAssay. High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, compounds from Cherry Pick 02. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.09 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.828 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.626 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.538 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.528 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.511 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.496 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.491 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.307 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.196 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.99 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 3.202 uM PUBCHEM_BIOASSAY: Discovery of Small Molecule Probes for H1N1 Influenza NS1A. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504399] ChEMBL. No reference
IC50 (functional) 4.89 uM PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2). (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 9.08 uM PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) = 11.8 uM PUBCHEM_BIOASSAY: Dose Response validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 14.6 uM PubChem BioAssay. Dose Response confirmation of uHTS hits for a small molecule inhibitors of MT1-MMP activation in a fluorescence assay set 1. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 24.9 uM PUBCHEM_BIOASSAY: Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 26.28 uM PubChem BioAssay. Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16). (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) > 80 uM PUBCHEM_BIOASSAY: Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) > 80 uM PUBCHEM_BIOASSAY: Dose Response orthogonal assay utilizing the direct end-point detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) > 80 uM PUBCHEM_BIOASSAY: Dose Response orthogonal kinetic assay utilizing the direct detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) > 100 uM PUBCHEM_BIOASSAY: Dose Response validation of uHTS RPN11 inhibitor hits using a MMP-2 Fluorescence assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 100 uM PubChem BioAssay. An HIV-1 Tat-TAR Fluorescence Polarization (FP) Counter Screen to evaluate Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 3.6626 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 3.9811 uM PubChem BioAssay. qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.9173 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.581 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.6795 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of Phosphoglycerate Kinase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 75.6863 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 100 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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