Detailed information for compound 153176

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 285.341 | Formula: C16H19N3O2
  • H donors: 1 H acceptors: 2 LogP: 3.3 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(c1)nc(o2)N1C(=O)NC2C1CCCCC2
  • InChi: 1S/C16H19N3O2/c1-10-7-8-14-12(9-10)18-16(21-14)19-13-6-4-2-3-5-11(13)17-15(19)20/h7-9,11,13H,2-6H2,1H3,(H,17,20)
  • InChiKey: IQXJMMLNUIUGIQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, alpha 2 451 aa 393 aa 25.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0012 0.0032 0.0041
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0724 0.1025
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0048 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0301 0.046
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0292 0.0445
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0308 0.003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0101 0.0139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Loa Loa (eye worm) beta-lactamase 0.0035 0.0308 0.0433
Echinococcus granulosus glycine receptor subunit beta 0.0015 0.0072 0.011
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0015 0.0072 0.0098
Entamoeba histolytica hypothetical protein 0.0011 0.0029 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0308 0.0433
Schistosoma mansoni fk506 binding protein 0.0077 0.0809 0.1235
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0016 0.0016
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1778 0.1778
Onchocerca volvulus 0.003 0.025 0.1703
Onchocerca volvulus Huntingtin homolog 0.0126 0.1392 1
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0077 0.0809 0.1145
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0311 0.0474
Onchocerca volvulus 0.0017 0.0101 0.0618
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Onchocerca volvulus 0.0012 0.0036 0.0147
Echinococcus granulosus transcription factor btf3 0.0036 0.032 0.0489
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0077 0.0809 0.1096
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0308 0.0469
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0394 0.0602
Brugia malayi Cathepsin L-like precursor 0.0012 0.0032 0.0046
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0015 0.0072 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0359 0.0548
Onchocerca volvulus 0.0017 0.0101 0.0618
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0016 0.0023
Schistosoma mansoni hypothetical protein 0.0077 0.0809 0.1235
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Loa Loa (eye worm) hypothetical protein 0.0035 0.0308 0.0433
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0077 0.0809 0.1096
Mycobacterium ulcerans two component transcriptional regulator 0.0063 0.065 0.0559
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0043 0.04 0.061
Loa Loa (eye worm) hypothetical protein 0.0077 0.0809 0.1145
Brugia malayi Cation transporter family protein 0.0015 0.0072 0.0102
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0177 0.0271
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0029 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0311 0.0474
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Trichomonas vaginalis rotamase, putative 0.0034 0.0301 0.046
Loa Loa (eye worm) hypothetical protein 0.0126 0.1392 0.1974
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.025 0.0351
Loa Loa (eye worm) hypothetical protein 0.0016 0.0081 0.011
Echinococcus granulosus chromobox protein 2 0.0011 0.0029 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0032 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Leishmania major fk506-binding protein 1-like protein 0.0558 0.6552 1
Leishmania major cathepsin L-like protease 0.0017 0.0101 0.0129
Trichomonas vaginalis fk506 binding protein, putative 0.0077 0.0809 0.1235
Plasmodium falciparum methionine aminopeptidase 2 0.0043 0.04 0.061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0308 0.0469
Echinococcus multilocularis cysteine protease 0.0017 0.0101 0.0101
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0032 0.0049
Brugia malayi Cathepsin L-like precursor 0.0012 0.0032 0.0046
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0308 0.0308
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0558 0.6552 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.04 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.0063 0.065 0.1557
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0311 0.0474
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.1667 0.1667
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.0063 0.065 0.0559
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0301 0.0459
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0077 0.0809 0.1096
Onchocerca volvulus 0.0012 0.0032 0.0116
Onchocerca volvulus 0.0015 0.0072 0.0407
Mycobacterium leprae PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN 0.0063 0.065 0.6876
Plasmodium vivax methionine aminopeptidase 2, putative 0.0043 0.04 0.061
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0102 0.0156
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0048 0.0074
Giardia lamblia Hypothetical protein 0.0077 0.0809 0.1096
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0072 0.0102
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0015 0.0072 0.0072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0463 0.0706
Echinococcus multilocularis Chromo domain 0.0011 0.0029 0.0029
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0301 0.0423
Onchocerca volvulus 0.0011 0.0029 0.0091
Onchocerca volvulus 0.0011 0.0029 0.0091
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0558 0.6552 1
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0371 0.0566
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0015 0.0072 0.011
Leishmania major methionine aminopeptidase 2, putative 0.0043 0.04 0.0586
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0101 0.0154
Onchocerca volvulus 0.0035 0.0308 0.2118
Echinococcus granulosus chromobox protein 1 0.007 0.0724 0.1106
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.1778 0.2714
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0015 0.0072 0.011
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0077 0.0809 0.1145
Onchocerca volvulus 0.0017 0.0101 0.0618
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0688 0.1049
Echinococcus multilocularis pyruvate kinase 0.0018 0.0102 0.0102
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Schistosoma mansoni cpg binding protein 0.0032 0.0271 0.0413
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0359 0.249
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0311 0.0474
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0081 0.0115
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0101 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.011 0.0168
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0308 0.0469
Echinococcus multilocularis fk506 binding protein 0.0558 0.6552 0.6552
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0463 0.0657
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0809 0.1235
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0015 0.0072 0.0102
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0101 0.0154
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0481 0.5636 0.8601
Loa Loa (eye worm) hypothetical protein 0.005 0.0488 0.0689
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0308 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0016 0.0018
Mycobacterium tuberculosis Conserved protein 0.0035 0.0308 0.003
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0016 0.0023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0463 0.0706
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0308 0.0469
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0016 0.0018
Toxoplasma gondii NAC domain-containing protein 0.0036 0.032 0.3833
Leishmania major cathepsin L-like protease 0.0067 0.0688 0.1026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0015 0.0072 0.0072
Plasmodium falciparum pyruvate kinase 0.0034 0.0301 0.0459
Brugia malayi beta-NAC-like protein 0.0036 0.032 0.0455
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0599 0.7041 1
Giardia lamblia Methionine aminopeptidase 0.0043 0.04 0.0462
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0077 0.0809 0.1235
Loa Loa (eye worm) ICD-1 protein 0.0036 0.032 0.0451
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0016 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0308 0.0469
Echinococcus granulosus glycine receptor subunit alpha 1 0.0015 0.0072 0.011
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0558 0.6552 1
Leishmania major cathepsin L-like protease 0.0017 0.0101 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Brugia malayi Heterochromatin protein 1 0.007 0.0724 0.1029
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0077 0.0809 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0036 0.0056
Entamoeba histolytica hypothetical protein 0.0011 0.0029 0.0044
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0308 0.0433
Schistosoma mansoni transcription factor btf3 0.0036 0.032 0.0489
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0032 0.0049
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0301 0.0423
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0029 0.0044
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0016 0.0016
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0016 0.0018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0101 0.0139
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0029 0.0041
Mycobacterium tuberculosis Possible two component transcriptional regulatory protein (probably LuxR-family) 0.0063 0.065 0.1557
Brugia malayi Cathepsin L-like precursor 0.0017 0.0101 0.0144
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0016 0.0025
Echinococcus multilocularis GPCR, family 2 0.0016 0.0081 0.0081
Schistosoma mansoni immunophilin 0.0558 0.6552 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0015 0.0072 0.011
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0063 0.065 0.1557
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0029 0.015
Entamoeba histolytica cysteine protease, putative 0.0017 0.0101 0.0154
Loa Loa (eye worm) FKBP5 protein 0.0558 0.6552 0.9306
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.0063 0.065 0.1557
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0016 0.0025
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0414 0.5017
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0558 0.6552 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0016 0.0018
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.1667 0.2544
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0558 0.6552 1
Echinococcus granulosus FTZ F1 alpha 0.001 0.0016 0.0025
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0414 0.0632
Echinococcus granulosus pyruvate kinase 0.0018 0.0102 0.0156
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0463 0.0706
Loa Loa (eye worm) hypothetical protein 0.0035 0.0308 0.0433
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0015 0.0072 0.0102
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0048 0.0074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.011 0.0168
Schistosoma mansoni hypothetical protein 0.0016 0.0081 0.0123
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0301 0.0459
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0558 0.6552 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0517 0.079
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0081 0.0081
Mycobacterium tuberculosis Probable transcriptional regulatory protein (LuxR-family) 0.0063 0.065 0.1557
Echinococcus granulosus GPCR family 2 0.0016 0.0081 0.0123
Brugia malayi chromobox protein homolog 3 0.0039 0.0359 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0015 0.0072 0.0102
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0048 0.0074
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0308 0.003
Brugia malayi hypothetical protein 0.0126 0.1392 0.1977
Echinococcus granulosus FK506 binding protein 2 0.0077 0.0809 0.1235
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0809 0.1235
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0688 0.1049
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0101 0.0154
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0043 0.04 0.4835
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0311 0.0474
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0029 0.0044
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0016 0.0025
Loa Loa (eye worm) cysteine protease 0.0017 0.0101 0.0139
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0016 0.0025
Brugia malayi beta-lactamase 0.0035 0.0308 0.0437
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0414 0.0632
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0077 0.0809 0.1145
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0292 0.347
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0015 0.0072 0.0098
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0102 0.1076
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0016 0.0016
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0003 0.0003
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0101 0.0101
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0558 0.6552 1
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0015 0.0072 0.0102
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0077 0.0809 0.1149
Mycobacterium ulcerans hypothetical protein 0.0035 0.0308 0.0011
Schistosoma mansoni nAChR subunit 0.0015 0.0072 0.011
Loa Loa (eye worm) ctsf protein 0.0017 0.0101 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Trichomonas vaginalis chromobox protein, putative 0.007 0.0724 0.1106
Schistosoma mansoni hypothetical protein 0.005 0.0487 0.0743
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0029 0.0041
Schistosoma mansoni thyroid hormone receptor 0.0139 0.1557 0.2377
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0043 0.04 0.2788
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1212
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0015 0.0072 0.011
Schistosoma mansoni chromobox protein 0.007 0.0724 0.1106
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0064
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0371 0.0417
Schistosoma mansoni nAChR subunit 0.0015 0.0072 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0809 0.1235
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0016 0.0016
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0077 0.0809 0.1149
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0029 0.0044
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0101 0.0618
Trichomonas vaginalis esterase, putative 0.0035 0.0308 0.0469
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.1778 0.2522
Schistosoma mansoni cpg binding protein 0.003 0.025 0.0382
Onchocerca volvulus 0.0091 0.0983 0.7027
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0015 0.0072 0.011
Echinococcus multilocularis chromobox protein 2 0.0011 0.0029 0.0029
Echinococcus granulosus cpg binding protein 0.0032 0.0271 0.0413
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0558 0.6552 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0301 0.0423
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Trichomonas vaginalis fk506-binding protein, putative 0.0077 0.0809 0.1235
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0048 0.0074
Onchocerca volvulus 0.0015 0.0072 0.0407
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.011 0.0168
Brugia malayi Cathepsin L-like precursor 0.0017 0.0101 0.0144
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0292 0.0445
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0015 0.0072 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0101 0.0154
Schistosoma mansoni nuclear hormone receptor 0.001 0.0016 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Brugia malayi Angiotensin-converting enzyme family protein 0.0599 0.7041 1
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0043 0.04 0.061
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0077 0.0809 0.2265
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0081 0.0115
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0015 0.0072 0.0102
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0029 0.0044
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0558 0.6552 1
Schistosoma mansoni chromobox protein 0.007 0.0724 0.1106
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0029 0.0041
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.04 0.061
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0077 0.0809 1
Onchocerca volvulus 0.0017 0.0101 0.0618
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0308 0.0469
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0016 0.0023
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0015 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Echinococcus granulosus pyruvate kinase 0.0018 0.0102 0.0156
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0016 0.0025
Schistosoma mansoni pyruvate kinase 0.0034 0.0301 0.0459
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0016 0.0025
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0015 0.0072 0.0102
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Entamoeba histolytica hypothetical protein 0.0038 0.0341 0.052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0308 0.0433
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0077 0.0809 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0016 0.0016
Brugia malayi hypothetical protein 0.0063 0.0645 0.0916
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0043 0.04 0.061
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0002 0.0003
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0101 0.0154
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.032 0.0489
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0223 0.034
Loa Loa (eye worm) hypothetical protein 0.0126 0.1392 0.1974
Echinococcus multilocularis nAChR subunit 0.0015 0.0072 0.0072
Echinococcus granulosus nAChR subunit 0.0015 0.0072 0.011
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.04 0.061
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0077 0.0809 1
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0077 0.0809 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0299 0.0421
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Leishmania major cathepsin L-like protease 0.0017 0.0101 0.0129
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0016 0.0016
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0301 0.0427
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0311 0.0474
Echinococcus multilocularis chromobox protein 1 0.007 0.0724 0.0724
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0017 0.0026
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0015 0.0072 0.0072
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0102 0.0156
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0003 0.0005
Leishmania major pyruvate kinase 0.0034 0.0301 0.0435
Brugia malayi beta-lactamase family protein 0.0035 0.0308 0.0437
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0481 0.5636 0.5636
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Echinococcus multilocularis pyruvate kinase 0.0034 0.0301 0.0301
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0292 0.0421
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0463 0.0463
Echinococcus multilocularis geminin 0.0351 0.4084 0.4084
Entamoeba histolytica hypothetical protein 0.0038 0.0341 0.052
Echinococcus granulosus glycine receptor subunit beta 0.0015 0.0072 0.011
Mycobacterium tuberculosis Conserved protein 0.0035 0.0308 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Leishmania major cathepsin L-like protease 0.0017 0.0101 0.0129
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0048 0.0233
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0016 0.0023
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0311 0.0311
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0311 0.0474
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0072 0.0102
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0015 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0072 0.011
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0301 0.0424
Schistosoma mansoni chromobox protein 0.0011 0.0029 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.032 0.0489
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0299 0.0425
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0308 0.003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0016 0.0025
Echinococcus granulosus pyruvate kinase 0.0034 0.0301 0.0459
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0029 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.032 0.0489
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Onchocerca volvulus 0.0077 0.0809 0.5762
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0029 0.0044
Echinococcus granulosus geminin 0.0351 0.4084 0.6232
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0015 0.0072 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0558 0.6552 1
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0016 0.0025
Onchocerca volvulus Cell death protein 3 homolog 0.0063 0.0645 0.4569
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0029 0.0044
Onchocerca volvulus 0.0077 0.0809 0.5762
Echinococcus multilocularis cysteine protease 0.0017 0.0101 0.0101
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0048 0.0074
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0029 0.0044
Trichomonas vaginalis fk506-binding protein, putative 0.0077 0.0809 0.1235
Loa Loa (eye worm) hypothetical protein 0.0063 0.0645 0.0912
Brugia malayi cathepsin L-like precursor 0.0012 0.0032 0.0046
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.032 0.0489
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0043 0.04 0.061
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0072 0.0102
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0558 0.6552 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0558 0.6552 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0101 0.0101
Echinococcus multilocularis expressed protein 0.0034 0.0301 0.0301
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0016 0.0025
Brugia malayi Protein cec-1. 0.0011 0.0029 0.0041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0652 0.0995
Plasmodium vivax vivapain-2 0.0017 0.0101 0.0154
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.011 0.0168
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0016 0.0023
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0558 0.6552 1
Echinococcus granulosus Chromo domain 0.0011 0.0029 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Loa Loa (eye worm) acetyltransferase 0.0149 0.1667 0.2364
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0308 0.0469
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0016 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0032 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0036
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0072 0.0102
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0048 0.0074
Schistosoma mansoni nAChR subunit 0.0015 0.0072 0.011
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0016 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0072 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0223 0.034
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0558 0.6552 1
Onchocerca volvulus 0.0031 0.0258 0.1758
Schistosoma mansoni hypothetical protein 0.0351 0.4084 0.6232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.032 0.0489
Loa Loa (eye worm) hypothetical protein 0.0481 0.5636 0.8004
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0301 0.0459
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0029 0.0044
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0081 0.0081
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0016 0.0023
Leishmania major hypothetical protein, conserved 0.0035 0.0308 0.0445
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0488 0.0689
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0029 0.0029
Schistosoma mansoni nAChR subunit 0.0015 0.0072 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0016 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Loa Loa (eye worm) hypothetical protein 0.0035 0.0308 0.0433
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.0063 0.065 0.1557
Loa Loa (eye worm) helicase 0.0011 0.0029 0.0036
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.011 0.0168
Leishmania major cathepsin L-like protease 0.0017 0.0101 0.0129
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0036
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0101 0.0154
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0101 0.0144
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0016 0.0025
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0614 0.754
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.032 0.0489
Brugia malayi CXXC zinc finger family protein 0.003 0.025 0.0356
Onchocerca volvulus 0.0063 0.0645 0.4569
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0029 0.0044
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0029 0.0044
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0048 0.0074
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0463 0.0653
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0049 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0016 0.0023
Echinococcus multilocularis pyruvate kinase 0.0018 0.0102 0.0102
Echinococcus multilocularis caspase 2 0.0063 0.0645 0.0645
Echinococcus granulosus glycine receptor subunit alpha 1 0.0015 0.0072 0.011
Onchocerca volvulus 0.0015 0.0072 0.0407
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Brugia malayi Cation transporter family protein 0.0015 0.0072 0.0102
Schistosoma mansoni hypothetical protein 0.0016 0.0081 0.0123
Echinococcus multilocularis thyroid hormone receptor alpha 0.0139 0.1557 0.1557
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0101 0.0129
Onchocerca volvulus Putative nachr subunit 0.0015 0.0072 0.0407
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.011 0.0168
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0558 0.6552 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0081 0.0123
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0301 0.2069
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0016 0.0025
Echinococcus multilocularis transcription factor btf3 0.0036 0.032 0.032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.011 0.0168
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0101 0.0618
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0129 0.1433 0.1433
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0558 0.6552 0.9306
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0029 0.0044
Echinococcus multilocularis glycine receptor subunit beta 0.0015 0.0072 0.0072
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0015 0.0072 0.0098
Schistosoma mansoni caspase-7 (C14 family) 0.0063 0.0645 0.0984
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0036
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0311 0.0442
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0301 0.0459
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0301 0.0423
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0016 0.0018
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.1617 0.2468
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0016 0.0016
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0301 0.0459
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0066 0.0101
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0308 0.0011
Brugia malayi Cathepsin L-like precursor 0.0017 0.0101 0.0144
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0016 0.0025
Schistosoma mansoni nAChR subunit 0.0015 0.0072 0.011
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0619 0.0944
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0308 0.0469
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0101 0.0154
Schistosoma mansoni nAChR subunit 0.0015 0.0072 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Brugia malayi Cation transporter family protein 0.0015 0.0072 0.0102
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0016 0.0023
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0029 0.0044
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0311 0.0474
Onchocerca volvulus Huntingtin homolog 0.0126 0.1392 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0015 0.0072 0.0098
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0308 0.0437
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0463 0.0463
Brugia malayi Cathepsin L-like precursor 0.0017 0.0101 0.0144
Brugia malayi steroid hormone receptor 0.001 0.0016 0.0023
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0101 0.0154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0077 0.0809 0.1235
Brugia malayi Cathepsin L-like precursor 0.0017 0.0101 0.0144
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0081 0.011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0016 0.0023
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0311 0.0474
Echinococcus multilocularis glycine receptor subunit beta 0.0015 0.0072 0.0072
Brugia malayi SET domain containing protein 0.0012 0.0036 0.0052
Leishmania major peptidylprolyl isomerase-like protein 0.0558 0.6552 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0015 0.0072 0.0102
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0015 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0017 0.0026
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0015 0.0072 0.011
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0032 0.0046
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0029 0.0044
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0558 0.6552 1
Entamoeba histolytica methionine aminopeptidase, putative 0.0043 0.04 0.061
Brugia malayi CHD4 protein 0.0013 0.0049 0.007
Toxoplasma gondii cathepsin CPL 0.0017 0.0101 0.1065
Echinococcus multilocularis pyruvate kinase 0.0018 0.0102 0.0102
Onchocerca volvulus 0.0017 0.0101 0.0618
Echinococcus granulosus cathepsin l1 0.0017 0.0101 0.0154
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0016 0.0018
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0394 0.0602
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0308 0.0469
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0016 0.0025
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0301 0.2069
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0077 0.0809 0.1149
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0077 0.0809 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0311 0.0474
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0101 0.0154
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0048 0.0074
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0016 0.0016
Brugia malayi Cell death protein 3 precursor 0.0063 0.0645 0.0916
Loa Loa (eye worm) hypothetical protein 0.0035 0.0308 0.0433
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.011 0.0168
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Brugia malayi hypothetical protein 0.0038 0.0341 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0016 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0558 0.6552 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0015 0.0072 0.011
Loa Loa (eye worm) hypothetical protein 0.0012 0.0032 0.0041
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.04 0.061
Trypanosoma brucei glucosidase, putative 0.0035 0.0311 0.0474
Echinococcus granulosus pyruvate kinase 0.0018 0.0102 0.0156
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0308 0.003
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0015 0.0072 0.011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0016 0.0023
Brugia malayi initiation factor 2-associated protein. 0.0043 0.04 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0359 0.0548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0414 0.5017
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0488 0.0693
Echinococcus multilocularis apoptotic protease activating factor 1 0.0063 0.0645 0.0645
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0101 0.0154
Plasmodium vivax vivapain-2 0.0017 0.0101 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0029 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0488 0.0693
Schistosoma mansoni cpg binding protein 0.0032 0.0271 0.0413
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0077 0.0809 1
Entamoeba histolytica hypothetical protein 0.0036 0.032 0.0489
Schistosoma mansoni immunophilin 0.0481 0.5636 0.8601
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0558 0.6552 1
Echinococcus granulosus chromobox protein 1 0.007 0.0724 0.1106
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0311 0.0474
Echinococcus granulosus expressed protein 0.0034 0.0301 0.046
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0301 0.0459
Echinococcus multilocularis 0.0077 0.0809 0.0809
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0311 0.0474
Leishmania major cathepsin L-like protease 0.0067 0.0688 0.1026
Trichomonas vaginalis chromobox protein, putative 0.007 0.0724 0.1106
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0029 0.0044
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0015 0.0072 0.011
Schistosoma mansoni rotamase 0.0034 0.0301 0.046
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0308 0.0469
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0558 0.6552 0.9307
Brugia malayi nuclear hormone receptor 0.001 0.0016 0.0023
Echinococcus granulosus caspase 2 0.0063 0.0645 0.0984
Mycobacterium ulcerans hypothetical protein 0.0063 0.065 0.0559
Leishmania major pyruvate kinase 0.0034 0.0301 0.0435
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0029 0.0044
Mycobacterium ulcerans hypothetical protein 0.0077 0.0809 0.0813
Brugia malayi excitatory GABA receptor EXP-1A 0.0015 0.0072 0.0102
Schistosoma mansoni pyruvate kinase 0.0034 0.0301 0.0459
Trichomonas vaginalis fk506-binding protein, putative 0.0558 0.6552 1
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0308 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0015 0.0072 0.0098
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0016 0.0023
Mycobacterium leprae Probable lipase LipE 0.0035 0.0308 0.0134
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0463 0.0706
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Leishmania major cathepsin L-like protease 0.0067 0.0688 0.1026
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0341 0.0341
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1778 0.1778
Trichomonas vaginalis rotamase, putative 0.0033 0.0292 0.0445
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0077 0.0809 0.1235
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0077 0.0809 1
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0341 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.032 0.0489
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0308 0.003
Brugia malayi beta-lactamase family protein 0.0035 0.0308 0.0437
Schistosoma mansoni hypothetical protein 0.0011 0.0029 0.0044
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.1778 0.2525
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Schistosoma mansoni chromobox protein 0.0011 0.0029 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0072 0.0102
Schistosoma mansoni alpha-glucosidase 0.0136 0.1516 0.2313
Onchocerca volvulus 0.0017 0.0101 0.0618
Loa Loa (eye worm) ACC-1 protein 0.0015 0.0072 0.0098
Echinococcus multilocularis pyruvate kinase 0.0027 0.0215 0.0215
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0301 0.0459
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0077 0.0809 0.1235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Echinococcus granulosus Chromobox protein 3 0.0011 0.0029 0.0044
Leishmania major basic transcription factor 3a, putative 0.0036 0.032 0.0465
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0101 0.0101
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0048 0.0074
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0292 0.0445
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0463 0.0706
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0015 0.0072 0.0072
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0029 0.015
Schistosoma mansoni hypothetical protein 0.0016 0.0081 0.0123
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0688 0.1049
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0043 0.04 0.061
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0101 0.0139
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0016 0.0025
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0016 0.0025
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.032 0.0489
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0311 0.0437
Echinococcus multilocularis cpg binding protein 0.0032 0.0271 0.0271
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Loa Loa (eye worm) hypothetical protein 0.0039 0.0359 0.0505
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0129 0.1433 0.2188
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0015 0.0072 0.011
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0077 0.0809 0.0809
Schistosoma mansoni hypothetical protein 0.0016 0.0081 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0101 0.0154
Loa Loa (eye worm) LGC-31 protein 0.0015 0.0072 0.0098
Onchocerca volvulus 0.0035 0.0308 0.2118
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0049 0.0049
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0029 0.0044
Schistosoma mansoni immunophilin 0.0558 0.6552 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Onchocerca volvulus 0.0017 0.0101 0.0618
Trichomonas vaginalis hypothetical protein 0.0011 0.0029 0.0044
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0301 0.2069
Schistosoma mansoni hypothetical protein 0.0351 0.4084 0.6232
Entamoeba histolytica hypothetical protein 0.0011 0.0029 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0101 0.0154
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0015 0.0072 0.011
Brugia malayi nuclear receptor NHR-88 0.001 0.0016 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0308 0.0469
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0301 0.0428
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0177 0.0247
Trichomonas vaginalis immunophilin, putative 0.0558 0.6552 1
Loa Loa (eye worm) ACC-1 protein 0.0015 0.0072 0.0098
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0341 0.052
Mycobacterium tuberculosis Conserved protein 0.0035 0.0308 0.003
Mycobacterium ulcerans beta-lactamase 0.0035 0.0308 0.0011
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.0063 0.065 0.0559
Giardia lamblia Pyruvate kinase 0.0034 0.0301 0.0308
Echinococcus granulosus methionyl aminopeptidase 2 0.0043 0.04 0.061
Schistosoma mansoni hypothetical protein 0.0034 0.0299 0.0457
Entamoeba histolytica hypothetical protein 0.0038 0.0341 0.052
Loa Loa (eye worm) hypothetical protein 0.0024 0.0177 0.0247
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0015 0.0072 0.011
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0311 0.3712
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0029 0.0041
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0049 0.0065
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0688 0.1049
Loa Loa (eye worm) fibroinase 0.0017 0.0101 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0308 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0016 0.0018
Toxoplasma gondii ABC1 family protein 0.0035 0.0308 0.3671
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0029 0.0029
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.032 0.0489
Echinococcus multilocularis pyruvate kinase 0.0034 0.0301 0.0301
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0048 0.0074
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.1667 0.2367
Entamoeba histolytica hypothetical protein 0.0038 0.0341 0.052
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0077 0.0809 0.1235
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0101 0.0154
Echinococcus multilocularis chromobox protein 1 0.007 0.0724 0.0724
Schistosoma mansoni hypothetical protein 0.0038 0.0341 0.052
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0048 0.0074
Schistosoma mansoni hypothetical protein 0.0063 0.0645 0.0984
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0017 0.0026
Mycobacterium ulcerans lipase LipD 0.0035 0.0308 0.0011
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0072 0.011
Schistosoma mansoni nAChR subunit 0.0015 0.0072 0.011
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0311 0.0474
Onchocerca volvulus 0.0015 0.0072 0.0407
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0301 0.3585
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0308 0.0469
Echinococcus granulosus apoptotic protease activating factor 1 0.0063 0.0645 0.0984
Brugia malayi Cathepsin L-like precursor 0.0017 0.0101 0.0144
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0414 0.0632
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0414 0.0632
Echinococcus granulosus cathepsin l1 0.0012 0.0032 0.0049
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0558 0.6552 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0049 0.0075
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0558 0.6552 0.9307
Echinococcus multilocularis methionyl aminopeptidase 2 0.0043 0.04 0.04
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0101 0.0618
Echinococcus granulosus pyruvate kinase 0.0034 0.0301 0.0459
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0015 0.0072 0.0072
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0077 0.0809 0.1212
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0029 0.0044
Loa Loa (eye worm) hypothetical protein 0.0063 0.0645 0.0912
Onchocerca volvulus 0.0015 0.0072 0.0407
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0015 0.0072 0.0102
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0394 0.2748
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0029 0.015
Schistosoma mansoni thyroid hormone receptor 0.0139 0.1557 0.2377
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0301 0.0427
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0029 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0098
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0015 0.0072 0.0072
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0048 0.0069
Onchocerca volvulus 0.0035 0.0308 0.2118
Echinococcus granulosus glycine receptor subunit alpha 1 0.0015 0.0072 0.011
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0308 0.003
Onchocerca volvulus 0.0015 0.0072 0.0407
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0292 0.0445
Schistosoma mansoni alpha-glucosidase 0.0136 0.1516 0.2313
Brugia malayi ecdysteroid receptor 0.001 0.0016 0.0023
Schistosoma mansoni coup transcription factor 0.001 0.0016 0.0025
Brugia malayi hypothetical protein 0.0011 0.0029 0.0041
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0016 0.0025
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0311 0.0474
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0015 0.0072 0.011
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0558 0.6552 0.6552
Mycobacterium ulcerans putative regulatory protein 0.0063 0.065 0.0559
Loa Loa (eye worm) initiation factor 2-associated protein 0.0043 0.04 0.0564
Loa Loa (eye worm) hypothetical protein 0.0012 0.0032 0.0041
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.2545 1
Schistosoma mansoni pyruvate kinase 0.0018 0.0102 0.0156
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0371 0.0566
Schistosoma mansoni alpha glucosidase 0.0035 0.0311 0.0474
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0015 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0018
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0311 0.045
Schistosoma mansoni hypothetical protein 0.0129 0.1433 0.2188
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0688 0.1049
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0015 0.0072 0.0102
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0081 0.0123

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 15 nM Binding affinity against GABA-A benzodiazepine receptor ChEMBL. 11133077
Ki (binding) = 15 nM Binding affinity against GABA-A benzodiazepine receptor ChEMBL. 11133077

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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