Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.1236 | 0.5 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1236 | 0.5 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1236 | 0.5 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1236 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1236 | 0.5 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.1236 | 0.5 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.1236 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1236 | 0.5 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.1236 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1236 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1236 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1236 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 22.3872 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | ChEMBL. | No reference |
Potency (functional) | 22.3872 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.