Detailed information for compound 1535334

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 462.516 | Formula: C26H27FN4O3
  • H donors: 0 H acceptors: 3 LogP: 3.15 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1CCCC1)Cn1cc(c2c1cccc2)C(=O)C(=O)N1CCN(CC1)c1ccccc1F
  • InChi: 1S/C26H27FN4O3/c27-21-8-2-4-10-23(21)28-13-15-30(16-14-28)26(34)25(33)20-17-31(22-9-3-1-7-19(20)22)18-24(32)29-11-5-6-12-29/h1-4,7-10,17H,5-6,11-16,18H2
  • InChiKey: GGTIPLLNIOJYCY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0082 0.0188
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.065 0.2499 0.8443
Echinococcus granulosus G protein coupled receptor 139 0.0103 0.0337 0.0413
Echinococcus granulosus tyrosine protein kinase HCK 0.003 0.005 0.0061
Onchocerca volvulus Dual oxidase homolog 0.0145 0.0503 0.1374
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0203
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0104 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0072
Echinococcus multilocularis geminin 0.0502 0.1913 0.235
Schistosoma mansoni 6-phosphofructokinase 0.0211 0.0764 0.0938
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0057 0.0156 0.053
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.0056 0.0107
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.002 0.0046
Echinococcus granulosus 6 phosphofructokinase 0.0211 0.0764 0.0938
Echinococcus multilocularis G protein coupled receptor 139 0.0103 0.0337 0.0413
Brugia malayi PXA domain containing protein 0.0038 0.0082 0.0188
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0766 0.2956 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0215 0.0568
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0027 0.0032
Schistosoma mansoni sulfide quinone reductase 0.0173 0.0613 0.0752
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0056 0.0068
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0234 0.0856 0.1978
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0082 0.019
Trypanosoma cruzi trypanothione reductase, putative 0.065 0.2499 0.2477
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0126 0.0324
Trypanosoma brucei DNA polymerase eta, putative 0.0034 0.0067 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1259 0.3427
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0084 0.0194
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0175 0.0145
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0081 0.0098
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0032 0.0056 0.0126
Onchocerca volvulus Alhambra homolog 0.003 0.0049 0.0133
Entamoeba histolytica P-glycoprotein-2 0.0032 0.0056 0.0361
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis phosphofructokinase, putative 0.0211 0.0764 0.207
Brugia malayi hypothetical protein 0.024 0.088 0.2034
Brugia malayi Bromodomain containing protein 0.0034 0.0064 0.0146
Echinococcus granulosus sodium channel protein 0.0082 0.0255 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0284 0.0756
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0027 0.0032
Echinococcus multilocularis calmodulin 0.0025 0.003 0.0037
Schistosoma mansoni loxhd1 0.008 0.0246 0.0301
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0032 0.0056 0.0126
Plasmodium vivax multidrug resistance protein 1, putative 0.0032 0.0056 0.0121
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0173 0.0613 0.1656
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0074 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Treponema pallidum thioredoxin reductase (trxB) 0.0173 0.0613 0.2428
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) hypothetical protein 0.0152 0.0531 0.1227
Entamoeba histolytica ABC transporter, putative 0.0029 0.0047 0.0295
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0196 0.0453
Brugia malayi Protein kinase domain containing protein 0.0047 0.0117 0.027
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0029 0.0047 0.009
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0173 0.0613 0.2376
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.023
Loa Loa (eye worm) hypothetical protein 0.0084 0.0265 0.0612
Loa Loa (eye worm) hypothetical protein 0.0504 0.1921 0.4441
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0056 0.0131
Echinococcus multilocularis allatostatin A receptor 0.0103 0.0337 0.0413
Leishmania major calmodulin, putative 0.0025 0.003 0.0005
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.1143 0.1121
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0037 0.0078 0.0095
Onchocerca volvulus 0.0029 0.0046 0.0125
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0123
Schistosoma mansoni voltage-gated potassium channel 0.0126 0.0429 0.0527
Leishmania major hypothetical protein, conserved 0.0173 0.0613 0.0589
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.05 0.1157
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0173 0.0613 0.2376
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0063 0.018 0.0155
Onchocerca volvulus 0.0103 0.0337 0.0919
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0215 0.0567
Echinococcus granulosus orexin receptor type 2 0.0103 0.0337 0.0413
Onchocerca volvulus 0.0084 0.0265 0.0722
Echinococcus granulosus jun protein 0.0085 0.0268 0.0329
Loa Loa (eye worm) G-protein coupled receptor 0.0103 0.0337 0.0779
Echinococcus multilocularis multidrug resistance protein 1 0.0032 0.0056 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0252 0.0926 0.2515
Plasmodium falciparum amino acid transporter, putative 0.004 0.0088 0.023
Mycobacterium ulcerans dehydrogenase 0.0173 0.0613 0.2376
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0103 0.0337 0.0779
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0025 0.0069
Echinococcus granulosus biogenic amine 5HT receptor 0.0346 0.1296 0.1592
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0226 0.0701
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0082 0.0188
Onchocerca volvulus 0.0072 0.0216 0.059
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0755 0.2915 0.986
Brugia malayi Cytochrome P450 family protein 0.0032 0.0056 0.0129
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0057 0.0156 0.0462
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0412 0.1559 0.1915
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0045 0.0108 0.0078
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0037 0.0078 0.0095
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0088 0.0107
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0082 0.01
Schistosoma mansoni multidrug resistance protein 0.0032 0.0056 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0094 0.0069
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0082 0.01
Loa Loa (eye worm) doublecortin family protein 0.008 0.0246 0.0568
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.0056 0.0107
Onchocerca volvulus Calmodulin homolog 0.0025 0.003 0.0081
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.0056 0.0107
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0282 0.1046 0.1024
Echinococcus granulosus neuropeptide Y receptor 0.0103 0.0337 0.0413
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0037 0.0078 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0323 0.0862
Plasmodium falciparum multidrug resistance protein 1 0.0032 0.0056 0.0121
Echinococcus granulosus acetylcholinesterase 0.0066 0.0191 0.0234
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.0078 0.0095
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0037 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0031 0.0062
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0173 0.0613 0.0752
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0278 0.1028 0.3472
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0173 0.0613 0.2018
Onchocerca volvulus 0.0197 0.0709 0.1936
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.012 0.0403 0.1304
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0047
Onchocerca volvulus 0.0944 0.366 1
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.003 0.0061
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0173 0.0613 0.0752
Onchocerca volvulus 0.0103 0.0337 0.0919
Brugia malayi hypothetical protein 0.0038 0.0082 0.0188
Toxoplasma gondii thioredoxin reductase 0.0766 0.2956 1
Echinococcus multilocularis calmodulin 0.0025 0.003 0.0037
Echinococcus granulosus tyrosine protein kinase Src42A 0.0032 0.0057 0.0069
Loa Loa (eye worm) hypothetical protein 0.0066 0.0191 0.0442
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Trichomonas vaginalis glutamate synthase, putative 0.0173 0.0613 0.1656
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0031 0.0003
Brugia malayi G protein-coupled receptor F59B2.13 0.0103 0.0337 0.0778
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0103 0.0337 0.0919
Onchocerca volvulus 0.004 0.0088 0.0239
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0067 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1852 0.7246 0.7237
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0203
Schistosoma mansoni glutamate synthase 0.0173 0.0613 0.0752
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0125 0.0095
Onchocerca volvulus 0.0103 0.0337 0.0919
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0133 0.0457 0.0434
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0045 0.0108 0.0131
Schistosoma mansoni hypothetical protein 0.0045 0.0111 0.0135
Brugia malayi Dopamine receptor protein 1 0.0504 0.1921 0.444
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0088 0.0107
Leishmania major NADH dehydrogenase, putative 0.0173 0.0613 0.0589
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0173 0.0613 0.2376
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0081 0.0056
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0032 0.0056 0.0126
Echinococcus multilocularis Polycystic kidney disease protein 0.008 0.0246 0.0301
Entamoeba histolytica calmodulin, putative 0.0025 0.003 0.0169
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0047
Trypanosoma cruzi Emopamil binding protein, putative 0.0282 0.1046 0.1019
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0076 0.0233 0.0537
Entamoeba histolytica beta-galactosidase, putative 0.017 0.0604 0.4471
Mycobacterium tuberculosis Probable reductase 0.0278 0.1028 0.3423
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0505 0.0481
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1955 0.5334
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0243 0.0644
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0032 0.0056 0.0131
Schistosoma mansoni adenoreceptor 0.0103 0.0337 0.0413
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0173 0.0613 0.1415
Echinococcus multilocularis ATP binding cassette sub family G 0.0029 0.0047 0.0057
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0019 0.0008 0.0009
Loa Loa (eye worm) TYRA-2 protein 0.0103 0.0337 0.0779
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0142 0.0492 0.0604
Loa Loa (eye worm) hypothetical protein 0.0028 0.0042 0.0097
Schistosoma mansoni hypothetical protein 0.0023 0.002 0.0024
Loa Loa (eye worm) heterochromatin protein 1 0.0079 0.0243 0.0562
Schistosoma mansoni voltage-gated potassium channel 0.0126 0.0429 0.0527
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0032 0.0056 0.0031
Trypanosoma brucei unspecified product 0.0024 0.0025 0.0000027249
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0173 0.0613 0.0752
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0233 0.0616
Echinococcus multilocularis G-protein coupled receptor, putative 0.0103 0.0337 0.0413
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0025 0.003 0.0036
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0226 0.0202
Echinococcus granulosus tachykinin peptides receptor 99D 0.0103 0.0337 0.0413
Brugia malayi Hypothetical WD-repeat protein F35G12.4 in chromosome III 0.0106 0.0349 0.0805
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.065 0.2499 0.2477
Entamoeba histolytica P-glycoprotein-2, putative 0.0032 0.0056 0.0361
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0126 0.0323
Loa Loa (eye worm) ABC transporter 0.0025 0.003 0.0068
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0056 0.0068
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0106 0.035 0.0326
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.01 0.0324 0.1021
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Toxoplasma gondii phosphofructokinase PFKII 0.0057 0.0156 0.0462
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0116 0.0389 0.0477
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.0202
Loa Loa (eye worm) neuropeptide F receptor 0.0103 0.0337 0.0779
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0056 0.0131
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0173 0.0613 0.2376
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.0203
Schistosoma mansoni hypothetical protein 0.0049 0.0125 0.0152
Echinococcus granulosus lipoxygenase domain containing protein 0.008 0.0246 0.0301
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0173 0.0613 0.0589
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0252 0.0581
Brugia malayi hypothetical protein 0.0114 0.0382 0.0881
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0082 0.01
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0106 0.035 0.0326
Schistosoma mansoni chromobox protein 0.0079 0.0243 0.0298
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0082 0.01
Trypanosoma brucei hypothetical protein, conserved 0.0173 0.0613 0.0589
Plasmodium vivax 6-phosphofructokinase, putative 0.0057 0.0156 0.0462
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Entamoeba histolytica phosphofructokinase, putative 0.0211 0.0764 0.5672
Brugia malayi SET domain containing protein 0.0028 0.004 0.0092
Plasmodium falciparum transporter, putative 0.004 0.0088 0.023
Plasmodium vivax multidomain scavenger receptor, putative 0.008 0.0246 0.0767
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0032 0.0067
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0032 0.0056 0.0026
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0173 0.0613 0.2018
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0047
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0032 0.0056 0.0126
Loa Loa (eye worm) hypothetical protein 0.0106 0.0349 0.0806
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0088 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.003 0.0048 0.0111
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0137 0.0355
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Brugia malayi larval opioid receptor 0.0103 0.0337 0.0778
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0063 0.0077
Echinococcus granulosus glutamate synthase 0.0173 0.0613 0.0752
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0027 0.0032
Onchocerca volvulus 0.0103 0.0337 0.0919
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.0056 0.0107
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1259 0.3427
Echinococcus granulosus hypothetical protein 0.0771 0.2976 0.3657
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0246 0.0651
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0156 0.0405
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0519 0.0637
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0045 0.0108 0.0078
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0173 0.0613 0.0584
Schistosoma mansoni DNA polymerase eta 0.0034 0.0067 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Echinococcus granulosus dnaJ subfamily B 0.0416 0.1573 0.1932
Trypanosoma brucei trypanothione reductase 0.0766 0.2956 0.2938
Loa Loa (eye worm) hypothetical protein 0.0346 0.1296 0.2997
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0027 0.0037 0.0045
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0173 0.0613 0.0752
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0049 0.0098
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0103 0.0337 0.0778
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0046 0.0106
Brugia malayi neuropeptide F receptor 0.0103 0.0337 0.0778
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1259 0.3427
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0133 0.0457 0.0561
Leishmania major cytochrome p450-like protein 0.0032 0.0056 0.0031
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.065 0.2499 0.307
Loa Loa (eye worm) beta-glucuronidase 0.0234 0.0853 0.1973
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0057 0.0156 0.0595
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0031 0.0037
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0082 0.01
Echinococcus granulosus ATP binding cassette sub family G 0.0029 0.0047 0.0057
Schistosoma mansoni voltage-gated potassium channel 0.0027 0.0037 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0082 0.0203
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0126 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0173 0.0613 0.2376
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0031 0.0001
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0091 0.0292 0.0358
Onchocerca volvulus 0.0067 0.0196 0.0533
Toxoplasma gondii NADPH-glutathione reductase 0.065 0.2499 0.8445
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Echinococcus multilocularis ATP binding cassette sub family G 0.0029 0.0047 0.0057
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0075 0.0229 0.0624
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0056 0.0068
Echinococcus multilocularis musashi 0.0081 0.0252 0.0309
Trichomonas vaginalis glutamate synthase, putative 0.0173 0.0613 0.1656
Schistosoma mansoni hypothetical protein 0.0103 0.0337 0.0413
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0029 0.0047 0.009
Schistosoma mansoni hypothetical protein 0.0032 0.0058 0.0071
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0233 0.0209
Entamoeba histolytica disulphide oxidoreductase, putative 0.0173 0.0613 0.4539
Plasmodium vivax RNA helicase-1, putative 0.0025 0.003 0.0033
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus multilocularis calmodulin 0.0025 0.003 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1259 0.3427
Echinococcus multilocularis jun protein 0.0085 0.0268 0.0329
Loa Loa (eye worm) hypothetical protein 0.0081 0.0252 0.0582
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0086 0.0105
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1113 0.4325 0.4308
Onchocerca volvulus 0.0103 0.0337 0.0919
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0125 0.0405
Echinococcus multilocularis neuropeptide receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0114
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0047
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0116 0.0389 0.0899
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0029 0.0047 0.0091
Echinococcus multilocularis chromobox protein 1 0.0079 0.0243 0.0298
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0019 0.0022
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.004 0.0088 0.0107
Leishmania major C-8 sterol isomerase-like protein 0.1113 0.4325 0.4311
Echinococcus granulosus eukaryotic initiation factor 4A 0.0025 0.003 0.0036
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0103 0.0337 0.0778
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0068 0.02 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0037 0.0045
Giardia lamblia Calmodulin 0.0025 0.003 0.0001
Echinococcus granulosus muscleblind protein 0.0152 0.0531 0.0651
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0108 0.0273
Schistosoma mansoni opsin-like receptor 0.0103 0.0337 0.0413
Schistosoma mansoni myosin xvIII 0.0103 0.0337 0.0413
Echinococcus granulosus serotonin receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.012 0.0403 0.0932
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0103 0.0337 0.0413
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1113 0.4325 1
Brugia malayi Beta-glucuronidase precursor 0.0234 0.0853 0.1972
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) hypothetical protein 0.0025 0.003 0.007
Brugia malayi Flap endonuclease-1 0.0025 0.0031 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0282 0.1046 0.1019
Entamoeba histolytica P-glycoprotein-5 0.0032 0.0056 0.0361
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0181 0.0547
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0103 0.0337 0.0413
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0102 0.0332 0.2433
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0076 0.0233 0.0822
Onchocerca volvulus 0.0103 0.0337 0.0919
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.0056 0.0107
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0252 0.0582
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.05 0.1157
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.065 0.2499 0.8445
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0085 0.0268 0.0329
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Loa Loa (eye worm) carboxylesterase 0.0066 0.0191 0.0442
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Schistosoma mansoni ABC transporter 0.0025 0.003 0.0036
Echinococcus granulosus 7tm_1 domain containing protein 0.0103 0.0337 0.0413
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0333 0.077
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0052 0.0027
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0025 0.0031 0.0037
Loa Loa (eye worm) TK/EGFR protein kinase 0.0145 0.0505 0.1169
Echinococcus multilocularis GPCR, family 2 0.0032 0.0058 0.0071
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0071
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0111 0.037 0.0992
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0082 0.0188
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.065 0.2499 1
Echinococcus granulosus microtubule associated protein 2 0.2078 0.8138 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.0318 0.039
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0084 0.0103
Brugia malayi glutamate synthase 0.0173 0.0613 0.1415
Loa Loa (eye worm) kinesin-like protein KLP2 0.0027 0.0037 0.0085
Plasmodium falciparum LCCL domain-containing protein 0.008 0.0246 0.0767
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0082 0.0188
Echinococcus multilocularis calmodulin 0.0025 0.003 0.0037
Echinococcus multilocularis Chromobox protein 3 0.0023 0.002 0.0024
Brugia malayi CHD4 protein 0.0024 0.0027 0.0061
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0025 0.0031 0.0171
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0103 0.0337 0.0413
Plasmodium falciparum kinesin-5 0.0027 0.0037 0.0056
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0032 0.0056 0.0126
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.003 0.0061
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0082 0.0203
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Echinococcus granulosus multidrug resistance protein 1 0.0032 0.0056 0.0068
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0094 0.0069
Plasmodium falciparum glutathione reductase 0.0766 0.2956 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0116 0.0389 0.0898
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0082 0.01
Toxoplasma gondii hypothetical protein 0.005 0.0127 0.0362
Brugia malayi jmjC domain containing protein 0.0098 0.0318 0.0734
Brugia malayi GnHR receptor homolog 0.0103 0.0337 0.0778
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0082 0.0255 0.0231
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0173 0.0613 0.4539
Toxoplasma gondii selenide, water dikinase 0.0173 0.0613 0.2018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0215 0.0568
Schistosoma mansoni neuropeptide F-like receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.024 0.088 0.2035
Treponema pallidum sodium- and chloride- dependent transporter 0.0234 0.0856 0.3404
Schistosoma mansoni amine GPCR 0.0103 0.0337 0.0413
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0082 0.0255 0.0313
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.0067 0.0082
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0175 0.0214
Echinococcus granulosus lamin dm0 0.0081 0.0252 0.0309
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0032 0.0056 0.0131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0046 0.0106
Schistosoma mansoni hypothetical protein 0.0502 0.1913 0.235
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.057 0.1859
Plasmodium falciparum calmodulin 0.0025 0.003 0.0034
Schistosoma mansoni neuropeptide f receptor 76f 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.008 0.0246 0.0568
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0173 0.0613 0.2034
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.0056 0.0107
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0133 0.0457 0.3374
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0037 0.0078 0.0095
Trypanosoma cruzi trypanothione reductase, putative 0.0766 0.2956 0.2934
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0067 0.0082
Trichomonas vaginalis chromobox protein, putative 0.0023 0.002 0.0034
Brugia malayi Doublecortin family protein 0.008 0.0246 0.0567
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0173 0.0613 0.1417
Schistosoma mansoni tyrosine kinase 0.0145 0.0505 0.062
Giardia lamblia ABC transporter 0.0029 0.0044 0.0058
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0103 0.0337 0.0413
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0031 0.0037
Leishmania major ferric reductase, putative 0.0068 0.02 0.0175
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0058 0.0133
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0173 0.0613 0.1415
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0103 0.0337 0.0413
Onchocerca volvulus 0.0114 0.0381 0.104
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0193 0.0236
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0095
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0037 0.0045
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0226 0.0197
Trypanosoma cruzi NADH dehydrogenase, putative 0.0173 0.0613 0.0584
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0081 0.0098
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0089 0.0613
Plasmodium vivax kinesin-5 0.0027 0.0037 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0273 0.0725
Echinococcus granulosus rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Plasmodium vivax ferrodoxin reductase, putative 0.0173 0.0613 0.2018
Schistosoma mansoni lamin 0.0081 0.0252 0.0309
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0139 0.0109
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0045 0.0108 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0001 0.0001
Trypanosoma cruzi Emopamil binding protein, putative 0.0282 0.1046 0.1019
Brugia malayi neuropeptide F receptor 0.0103 0.0337 0.0778
Schistosoma mansoni hypothetical protein 0.0032 0.0058 0.0071
Echinococcus multilocularis 6 phosphofructokinase 0.0211 0.0764 0.0938
Trypanosoma brucei C-8 sterol isomerase, putative 0.1113 0.4325 0.4311
Brugia malayi G-protein coupled receptor 0.0103 0.0337 0.0778
Brugia malayi Carboxylesterase family protein 0.0066 0.0191 0.044
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0049 0.0098
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.003 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.0056 0.0107
Echinococcus multilocularis inositol monophosphatase 1 0.0111 0.037 0.0454
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0175 0.0607
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0088 0.0107
Echinococcus granulosus geminin 0.0502 0.1913 0.235
Onchocerca volvulus 0.0103 0.0337 0.0919
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0226 0.0701
Onchocerca volvulus 0.003 0.0048 0.013
Trichomonas vaginalis glycoside hydrolase, putative 0.0252 0.0926 0.2515
Schistosoma mansoni sodium-dependent amino acid transporter 0.004 0.0088 0.0107
Echinococcus granulosus thioredoxin glutathione reductase 0.0766 0.2956 0.3631
Loa Loa (eye worm) hypothetical protein 0.0114 0.0382 0.0882
Echinococcus granulosus intermediate filament protein 0.0081 0.0252 0.0309
Schistosoma mansoni sodium/chloride dependent transporter 0.0234 0.0856 0.1051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0108 0.0273
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0032 0.0056 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Schistosoma mansoni hypothetical protein 0.0032 0.0056 0.0068
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0173 0.0613 0.1656
Brugia malayi Valyl-tRNA synthetase 0.0023 0.002 0.0046
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0126 0.0101
Echinococcus granulosus neuropeptides capa receptor 0.0103 0.0337 0.0413
Plasmodium falciparum glutathione reductase 0.065 0.2499 0.8445
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0088 0.0107
Echinococcus multilocularis muscleblind protein 0.0152 0.0531 0.0651
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0126 0.0096
Echinococcus granulosus neuropeptide Y receptor 0.0103 0.0337 0.0413
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0095
Onchocerca volvulus 0.0103 0.0337 0.0919
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0215 0.0567
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus multilocularis kinesin family 1 0.0206 0.0746 0.0916
Schistosoma mansoni rab6-interacting 0.008 0.0246 0.0301
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.0203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0242 0.0642
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0088 0.0107
Schistosoma mansoni growth hormone secretagogue receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0078 0.0095
Plasmodium vivax glutathione reductase, putative 0.0766 0.2956 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0173 0.0613 0.0589
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.0185
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0025 0.003 0.0018
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0203
Schistosoma mansoni biogenic amine receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.0066 0.0191 0.0442
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0357 0.134 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0032 0.0056 0.0122
Echinococcus granulosus alpha 1A adrenergic receptor 0.0103 0.0337 0.0413
Schistosoma mansoni tyrosine kinase 0.0079 0.0241 0.0296
Brugia malayi Muscleblind-like protein 0.0152 0.0531 0.1226
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0126 0.0323
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2549 1 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus granulosus neuropeptide receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.019
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0037 0.0085
Trichomonas vaginalis beta-mannosidase, putative 0.0082 0.0254 0.0673
Trypanosoma cruzi target of rapamycin kinase 3 0.0106 0.035 0.0321
Toxoplasma gondii calmodulin, putative 0.0025 0.003 0.0034
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0133 0.0457 0.0429
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0125 0.0101
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.065 0.2499 0.307
Echinococcus granulosus multidrug resistance protein 1 0.0032 0.0056 0.0068
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0084 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0215 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0052 0.0027
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) hypothetical protein 0.0037 0.0077 0.0178
Loa Loa (eye worm) hypothetical protein 0.0114 0.0381 0.0881
Trichomonas vaginalis abcb9, putative 0.0032 0.0056 0.0131
Trypanosoma brucei NADH dehydrogenase 0.0173 0.0613 0.0589
Brugia malayi PXA domain containing protein 0.0038 0.0082 0.0188
Loa Loa (eye worm) programmed cell death 8 0.0173 0.0613 0.1417
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0032 0.0056 0.0126
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.008 0.0246 0.0568
Echinococcus granulosus g-protein coupled receptor 0.0103 0.0337 0.0413
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.002 0.0024
Leishmania major phosphatidylinositol 3-kinase, putative 0.0045 0.0108 0.0083
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0056 0.0131
Echinococcus granulosus epidermal growth factor receptor 0.0145 0.0505 0.062
Brugia malayi intermediate filament protein 0.0081 0.0252 0.0581
Trypanosoma brucei calmodulin 0.0025 0.003 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0125 0.0289
Giardia lamblia NADH oxidase lateral transfer candidate 0.065 0.2499 1
Schistosoma mansoni hypothetical protein 0.0032 0.0058 0.0071
Trichomonas vaginalis chromobox protein, putative 0.0023 0.002 0.0034
Schistosoma mansoni inositol monophosphatase 0.0111 0.037 0.0454
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0173 0.0613 0.1656
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0126 0.0154
Echinococcus granulosus g protein coupled receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0323 0.0862
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.1331 0.3623
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0077 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0233 0.0616
Trichomonas vaginalis phosphofructokinase, putative 0.0211 0.0764 0.207
Schistosoma mansoni chromobox protein 0.0079 0.0243 0.0298
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.037 0.0341
Schistosoma mansoni hypothetical protein 0.0019 0.0008 0.0009
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0031 0.0006
Echinococcus multilocularis microtubule associated protein 2 0.2078 0.8138 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0103 0.0337 0.0413
Onchocerca volvulus 0.0075 0.0229 0.0624
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0103 0.0337 0.0779
Echinococcus multilocularis RUN 0.008 0.0246 0.0301
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.0233 0.0209
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.003 0.0036
Brugia malayi ABC transporter family protein 0.0025 0.003 0.0067
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0164 0.0561
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0084 0.0102
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0173 0.0613 0.1656
Onchocerca volvulus 0.0103 0.0337 0.0919
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0173 0.0613 0.4539
Schistosoma mansoni 6-phosphofructokinase 0.0211 0.0764 0.0938
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0032 0.0056 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.0056 0.0068
Echinococcus granulosus chromobox protein 2 0.0023 0.002 0.0024
Loa Loa (eye worm) 6-phosphofructokinase 0.0211 0.0764 0.1766
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0037 0.0045
Toxoplasma gondii hypothetical protein 0.006 0.0169 0.0507
Onchocerca volvulus 0.0081 0.0252 0.0686
Echinococcus multilocularis neuropeptide receptor A26 0.057 0.2184 0.2683
Entamoeba histolytica protein kinase rad3, putative 0.0025 0.0031 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.035 0.0936
Treponema pallidum oxidoreductase 0.0173 0.0613 0.2428
Schistosoma mansoni hypothetical protein 0.0502 0.1913 0.235
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Leishmania major calmodulin, putative 0.0025 0.003 0.0005
Schistosoma mansoni hypothetical protein 0.0179 0.064 0.0786
Entamoeba histolytica kinesin, putative 0.0027 0.0037 0.0218
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Echinococcus granulosus dna polymerase kappa 0.0062 0.0175 0.0214
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0173 0.0613 0.2006
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0156 0.0405
Echinococcus granulosus flap endonuclease 1 0.0025 0.0031 0.0037
Loa Loa (eye worm) G-protein coupled receptor 0.0103 0.0337 0.0779
Entamoeba histolytica P-glycoprotein 5, putative 0.0032 0.0056 0.0361
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0056 0.0131
Loa Loa (eye worm) norepinephrine transporter 0.0234 0.0856 0.1979
Echinococcus multilocularis 0.0032 0.0056 0.0068
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0103 0.0337 0.0778
Mycobacterium ulcerans flavoprotein disulfide reductase 0.065 0.2499 1
Entamoeba histolytica thioredoxin reductase, putative 0.0173 0.0613 0.4539
Schistosoma mansoni biogenic amine (5HT) receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis serotonin receptor 0.0346 0.1296 0.1592
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0082 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0001 0.0001
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Schistosoma mansoni 60S ribosomal protein L21 0.0022 0.0019 0.0023
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0211 0.0764 0.2556
Loa Loa (eye worm) hypothetical protein 0.0032 0.0056 0.0129
Schistosoma mansoni intermediate filament proteins 0.0081 0.0252 0.0309
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1852 0.7246 0.7237
Echinococcus multilocularis conserved hypothetical protein 0.0668 0.257 0.3158
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0211 0.0764 0.3034
Schistosoma mansoni cytochrome P450 0.0032 0.0056 0.0068
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0233 0.0286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2131 0.835 0.8345
Trichomonas vaginalis glutathione reductase, putative 0.065 0.2499 0.6823
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0082 0.01
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0031 0.0036
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0103 0.0337 0.0413
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.0056 0.0107
Trichomonas vaginalis beta-galactosidase, putative 0.0252 0.0926 0.2515
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0233 0.0616
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0055 0.015 0.0125
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1852 0.7246 0.7239
Brugia malayi follicle stimulating hormone receptor 0.0103 0.0337 0.0778
Loa Loa (eye worm) adenylyl cyclase 3 0.0075 0.0229 0.0529
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.065 0.2499 1
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.024 0.088 0.2034
Schistosoma mansoni lamin 0.0081 0.0252 0.0309
Echinococcus granulosus survival motor neuron protein 1 0.024 0.088 0.1081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0001 0.0001
Echinococcus multilocularis cpg binding protein 0.0031 0.0053 0.0064
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0156 0.0405
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0513 0.1955 0.4521
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0037 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.035 0.0936
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.065 0.2499 0.5778
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.0292 0.0358
Echinococcus multilocularis serotonin receptor 0.0346 0.1296 0.1592
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0025 0.0031 0.0037
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0196 0.024
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0033 0.0068
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0111 0.037 0.272
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0173 0.0613 0.2006
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0031 0.0006
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.002 0.0095
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) TK protein kinase 0.003 0.005 0.0115
Loa Loa (eye worm) hypothetical protein 0.0234 0.0856 0.1979
Schistosoma mansoni neuropeptide F-like receptor 0.0103 0.0337 0.0413
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.002 0.0024
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.0056 0.0107
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0234 0.0856 0.1051
Schistosoma mansoni biogenic amine receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0082 0.01
Toxoplasma gondii kinesin motor domain-containing protein 0.0027 0.0037 0.0056
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0126 0.0096
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0056 0.0108
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0088 0.0107
Giardia lamblia Thioredoxin reductase 0.0173 0.0613 0.2359
Loa Loa (eye worm) solute carrier family 6 member 4 0.0234 0.0856 0.1979
Onchocerca volvulus 0.0103 0.0337 0.0919
Echinococcus granulosus allatostatin A receptor 0.0103 0.0337 0.0413
Brugia malayi putative neuropeptide receptor NPR1 0.0103 0.0337 0.0778
Leishmania major trypanothione reductase 0.0766 0.2956 0.2938
Leishmania major DNA polymerase kappa, putative 0.0041 0.0094 0.0069
Onchocerca volvulus 0.004 0.0088 0.0239
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.019
Brugia malayi Pre-SET motif family protein 0.0829 0.3207 0.7414
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0103 0.0337 0.0413
Schistosoma mansoni amine GPCR 0.0103 0.0337 0.0413
Echinococcus multilocularis serotonin transporter 0.0234 0.0856 0.1051
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1259 0.3427
Onchocerca volvulus 0.0103 0.0337 0.0919
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0032 0.0056 0.0106
Plasmodium falciparum thioredoxin reductase 0.065 0.2499 0.8445
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.012 0.0403 0.0495
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0108 0.0273
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.0117 0.0143
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Brugia malayi MAP kinase sur-1 0.0049 0.0126 0.029
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0519 0.1198
Entamoeba histolytica hypothetical protein 0.0024 0.0025 0.0129
Schistosoma mansoni jun-related protein 0.0069 0.0205 0.0251
Schistosoma mansoni hypothetical protein 0.0416 0.1573 0.1932
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Giardia lamblia DNA repair protein RAD52 0.0357 0.134 0.5307
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.0056 0.0107
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0103 0.0337 0.0413
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0173 0.0613 0.1656
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0031 0.0063
Onchocerca volvulus 0.0114 0.0381 0.104
Loa Loa (eye worm) phosphofructokinase 0.0211 0.0764 0.1766
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2549 1 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0173 0.0613 0.0584
Echinococcus granulosus g protein coupled receptor 0.0103 0.0337 0.0413
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0126 0.0359
Loa Loa (eye worm) hypothetical protein 0.008 0.0246 0.0568
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0101 0.0072
Mycobacterium ulcerans ferredoxin reductase 0.0173 0.0613 0.2376
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0173 0.0613 0.2376
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Schistosoma mansoni beta-mannosidase 0.0082 0.0254 0.0311
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0173 0.0613 0.2376
Loa Loa (eye worm) hypothetical protein 0.0083 0.0259 0.0598
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0173 0.0613 0.1656
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.1143 0.1117
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0049 0.006
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0049 0.006
Echinococcus granulosus kinesin family 1 0.0206 0.0746 0.0916
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0037 0.0045
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0173 0.0613 0.4539
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0037 0.0085
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0056 0.0131
Echinococcus granulosus peregrin 0.0034 0.0064 0.0077
Echinococcus granulosus expressed protein 0.0745 0.2872 0.3529
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.0056 0.0107
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0103 0.0337 0.0413
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.023
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.0056 0.0107
Echinococcus multilocularis g protein coupled receptor 0.0103 0.0337 0.0413
Schistosoma mansoni glutamate synthase 0.0173 0.0613 0.0752
Echinococcus granulosus CalModulin family member cmd 1 0.0025 0.003 0.0037
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0025 0.003 0.0005
Echinococcus granulosus tyrosine protein kinase Src64B 0.0037 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.019
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0029 0.0047 0.0022
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0173 0.0613 0.0752
Treponema pallidum ATP-dependent RNA helicase 0.0025 0.003 0.009
Trypanosoma cruzi ABC transporter, putative 0.0029 0.0047 0.0017
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0126 0.0154
Echinococcus granulosus cpg binding protein 0.0031 0.0053 0.0064
Schistosoma mansoni fkbp-rapamycin associated protein 0.0025 0.0031 0.0037
Giardia lamblia GTOR 0.0133 0.0457 0.1731
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.1143 0.1121
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0103 0.0337 0.0413
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.162 0.6329 0.7776
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.004 0.0088 0.0107
Brugia malayi Dopamine receptor 0.0103 0.0337 0.0778
Echinococcus granulosus tyrosine protein kinase Lyn 0.0038 0.008 0.0098
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0126 0.0323
Brugia malayi G protein-coupled receptor 0.0103 0.0337 0.0778
Echinococcus multilocularis tyrosine protein kinase HCK 0.003 0.005 0.0061
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0077 0.0094
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0082 0.01
Loa Loa (eye worm) hypothetical protein 0.0389 0.1468 0.3394
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0088 0.0107
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0126 0.0101
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0323 0.0862
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0519 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0323 0.0862
Loa Loa (eye worm) hypothetical protein 0.0197 0.0709 0.1639
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.0056 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0001 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.012 0.0403 0.0495
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0233 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Echinococcus granulosus somatostatin receptor 0.0103 0.0337 0.0413
Leishmania major ATP-dependent phosphofructokinase 0.0211 0.0764 0.0741
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0058 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0103 0.0337 0.0413
Echinococcus granulosus calmodulin 0.0025 0.003 0.0036
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0196 0.0452
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) hypothetical protein 0.0032 0.0056 0.0129
Echinococcus granulosus inositol monophosphatase 1 0.0111 0.037 0.0454
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0037 0.0045
Brugia malayi Serotonin receptor 0.0548 0.2097 0.4847
Mycobacterium ulcerans glutamate synthase subunit beta 0.0173 0.0613 0.2376
Trypanosoma cruzi hypothetical protein, conserved 0.0173 0.0613 0.0584
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0029 0.0047 0.009
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0103 0.0337 0.0413
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0243 0.0644
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0173 0.0613 0.2018
Plasmodium vivax 6-phosphofructokinase, putative 0.0057 0.0156 0.0462
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0082 0.01
Echinococcus granulosus neuropeptide s receptor 0.057 0.2184 0.2683
Echinococcus granulosus Polycystic kidney disease protein 0.008 0.0246 0.0301
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0047
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0068 0.02 0.017
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0173 0.0613 0.2018
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.065 0.2499 0.8445
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.023 0.0281
Loa Loa (eye worm) thioredoxin reductase 0.0766 0.2956 0.6834
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0173 0.0613 0.2018
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0032 0.0056 0.0126
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0173 0.0613 0.2018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Schistosoma mansoni histamine h1 receptor 0.0103 0.0337 0.0413
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0032 0.0056 0.0126
Echinococcus multilocularis neuropeptide Y receptor 0.0103 0.0337 0.0413
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0133 0.0457 0.0434
Plasmodium vivax hypothetical protein, conserved 0.004 0.0088 0.023
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0173 0.0613 0.0752
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0056 0.0131
Mycobacterium ulcerans NADH dehydrogenase 0.0173 0.0613 0.2376
Echinococcus granulosus insulin receptor 0.0047 0.0117 0.0143
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0082 0.01
Entamoeba histolytica hypothetical protein 0.0038 0.0082 0.0558
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0173 0.0613 0.4539
Schistosoma mansoni amine GPCR 0.0103 0.0337 0.0413
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0056 0.0068
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0173 0.0613 0.0752
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.002 0.0034
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0088 0.0107
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0078 0.0095
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.065 0.2499 1
Loa Loa (eye worm) SRC-1 0.0037 0.0078 0.0181
Onchocerca volvulus 0.0103 0.0337 0.0919
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.012 0.0403 0.0931
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0278 0.1028 0.3423
Echinococcus granulosus Chromobox protein 3 0.0023 0.002 0.0024
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0037 0.0078 0.0095
Echinococcus multilocularis somatostatin receptor 0.0103 0.0337 0.0413
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0125 0.0289
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0082 0.01
Trypanosoma brucei ABC transporter, putative 0.0029 0.0047 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0278 0.1028 0.3423
Echinococcus multilocularis voltage gated potassium channel 0.0037 0.0077 0.0094
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.01 0.0324 0.1036
Echinococcus granulosus tm gpcr rhodopsin 0.0103 0.0337 0.0413
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0173 0.0613 0.2018
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0164 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.035 0.0936
Trichomonas vaginalis phosphofructokinase, putative 0.0211 0.0764 0.207
Echinococcus granulosus tm gpcr rhodopsin 0.0905 0.3504 0.4306
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0025 0.0015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0191 0.0234
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0025 0.003 0.0168
Echinococcus granulosus neuropeptides capa receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis epidermal growth factor receptor 0.0145 0.0505 0.062
Leishmania major calmodulin, putative 0.0025 0.003 0.0005
Echinococcus granulosus ATP binding cassette sub family G 0.0029 0.0047 0.0057
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0226 0.0701
Schistosoma mansoni tyrosine kinase 0.0077 0.0234 0.0287
Leishmania major eukaryotic initiation factor 4a, putative 0.0025 0.003 0.0005
Brugia malayi hypothetical protein 0.0075 0.0226 0.0522
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0058 0.0135
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0067 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.0056 0.0107
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0037 0.0079
Loa Loa (eye worm) acetyltransferase 0.0149 0.0519 0.1199
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0056 0.0131
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.004 0.0088 0.0202
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0056 0.0131
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0265 0.0325
Schistosoma mansoni hypothetical protein 0.0173 0.0613 0.0752
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0233 0.0286
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0086 0.0105
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0032 0.0056 0.0126
Schistosoma mansoni biogenic amine receptor 0.0103 0.0337 0.0413
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0032 0.0056 0.0031
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus multilocularis dro:myosuppressin receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) glutathione reductase 0.0766 0.2956 0.6834
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2131 0.835 0.8346
Schistosoma mansoni cpg binding protein 0.0029 0.0046 0.0056
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0032 0.0057 0.0069
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0173 0.0613 0.2006
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0196 0.0172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0403 0.0495
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0173 0.0613 0.1656
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.009 0.011
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0082 0.01
Onchocerca volvulus 0.0142 0.0492 0.1344
Leishmania major dihydrolipoamide dehydrogenase, putative 0.065 0.2499 0.2481
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.0067 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0323 0.0862
Loa Loa (eye worm) melatonin receptor type 1A 0.0103 0.0337 0.0779
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0173 0.0613 0.0752
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0101 0.0077
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus granulosus peptide allatostatin:somatostatin 0.0103 0.0337 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0023 0.002 0.0034
Trypanosoma brucei ATP-binding cassette protein, putative 0.0029 0.0047 0.0022
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0191 0.0442
Schistosoma mansoni hypothetical protein 0.0032 0.0058 0.0071
Echinococcus multilocularis chromobox protein 2 0.0023 0.002 0.0024
Echinococcus multilocularis neuropeptides capa receptor 0.0103 0.0337 0.0413
Giardia lamblia Glutamate synthase 0.0173 0.0613 0.2359
Leishmania major hypothetical protein, conserved 0.0173 0.0613 0.0589
Brugia malayi Carboxylesterase family protein 0.0066 0.0191 0.044
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0103 0.0337 0.0778
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1259 0.3427
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0104 0.0262
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0148 0.0124
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0025 0.003 0.0033
Brugia malayi hypothetical protein 0.004 0.0088 0.0202
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0082 0.01
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus multilocularis chromobox protein 1 0.0079 0.0243 0.0298
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0068 0.02 0.0175
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0084 0.0102
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.0117 0.0271
Leishmania major p-glycoprotein 0.0032 0.0056 0.0031
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0025 0.003 0.0036
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0058 0.0071
Schistosoma mansoni sulfide quinone reductase 0.0173 0.0613 0.0752
Leishmania major cytochrome p450-like protein 0.0032 0.0056 0.0031
Echinococcus multilocularis dna polymerase eta 0.0034 0.0067 0.0082
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0088 0.0107
Trichomonas vaginalis abcb9, putative 0.0032 0.0056 0.0131
Echinococcus multilocularis lamin dm0 0.0081 0.0252 0.0309
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0032 0.0056 0.0121
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.0241 0.0296
Echinococcus granulosus chromobox protein 1 0.0079 0.0243 0.0298
Echinococcus granulosus GPCR family 2 0.0032 0.0058 0.0071
Leishmania major hypothetical protein, conserved 0.0173 0.0613 0.0589
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0032 0.0056 0.0125
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0173 0.0613 0.0589
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0058 0.0071
Schistosoma mansoni inositol monophosphatase 0.0111 0.037 0.0454
Leishmania major DNA polymerase eta, putative 0.0034 0.0067 0.0042
Schistosoma mansoni hypothetical protein 0.0069 0.0205 0.0251
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.065 0.2499 0.2477
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0037 0.0078 0.0095
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0173 0.0613 0.2006
Loa Loa (eye worm) multidrug resistance protein 3 0.0032 0.0056 0.0129
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0082 0.019
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0226 0.0197
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0175 0.0607
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0133 0.0457 0.1056
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Echinococcus granulosus multidrug resistance protein 1 0.0032 0.0056 0.0068
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0082 0.0188
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0126 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0246 0.0651
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0196 0.024
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0056 0.0068
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0173 0.0613 0.0584
Chlamydia trachomatis thioredoxin reductase 0.0173 0.0613 0.2376
Mycobacterium ulcerans 6-phosphofructokinase 0.0211 0.0764 0.2986
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0103 0.0337 0.0413
Brugia malayi 6-phosphofructokinase 0.0211 0.0764 0.1765
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.037 0.0341
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0126 0.0101
Brugia malayi polk-prov protein 0.0038 0.0081 0.0186
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0037 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0215 0.0567
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0125 0.0095
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0045 0.0108 0.0083
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0077 0.0094
Mycobacterium ulcerans hypothetical protein 0.0162 0.057 0.2201
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0196 0.0166
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0076 0.0233 0.0286
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0056 0.0131
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0031 0.0035
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0531 0.0651
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0173 0.0613 0.0589
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0025 0.003 0.0081
Trichomonas vaginalis calmodulin, putative 0.0025 0.003 0.0061
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.0101 0.0331 0.0765
Echinococcus granulosus tyrosine protein kinase Blk 0.0034 0.0064 0.0078
Brugia malayi ABC transporter family protein 0.0032 0.0056 0.0128
Brugia malayi AKH receptor 0.0103 0.0337 0.0778
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0173 0.0613 0.1656
Echinococcus granulosus lipoxygenase domain containing protein 0.008 0.0246 0.0301
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Giardia lamblia Kinesin-5 0.0027 0.0037 0.0027
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0095
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0478 0.1818 0.4202
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0032 0.0056 0.0126
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0203
Schistosoma mansoni neuropeptide receptor 0.0103 0.0337 0.0413
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0108 0.0247
Onchocerca volvulus Glucosylceramidase homolog 0.0336 0.1259 0.344
Plasmodium vivax amine transporter, putative 0.004 0.0088 0.023
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0111 0.037 0.0992
Echinococcus multilocularis 0.0045 0.0108 0.0131
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0173 0.0613 0.0752
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0196 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0108 0.0273
Loa Loa (eye worm) hypothetical protein 0.007 0.0206 0.0476
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0045 0.0108 0.0131
Mycobacterium tuberculosis Probable oxidoreductase 0.0755 0.2915 0.986
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0135
Echinococcus multilocularis thioredoxin glutathione reductase 0.0766 0.2956 0.3631
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0173 0.0613 0.0589
Brugia malayi Adenylyl cyclase protein 0.0075 0.0229 0.0528
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.065 0.2499 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.0078 0.0095
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.0067 0.0155
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0037 0.0045
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0175 0.015
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0164 0.0473
Loa Loa (eye worm) inositol-1 0.0111 0.037 0.0856
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0088 0.0107
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0211 0.0764 0.0741
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0173 0.0613 0.2376
Brugia malayi Cytochrome P450 family protein 0.0049 0.0125 0.0288
Entamoeba histolytica P-glycoprotein-1 0.0032 0.0056 0.0361
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0037 0.0077 0.0177
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.002 0.0046
Mycobacterium tuberculosis Probable dehydrogenase 0.0278 0.1028 0.3423
Echinococcus granulosus rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Schistosoma mansoni microtubule-associated protein tau 0.2078 0.8138 1
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0056 0.0131
Echinococcus multilocularis orexin receptor type 2 0.0103 0.0337 0.0413
Onchocerca volvulus 0.0025 0.003 0.0081
Brugia malayi Serotonin receptor 0.0103 0.0337 0.0778
Brugia malayi eukaryotic initiation factor 4A 0.0025 0.003 0.0068
Mycobacterium ulcerans hypothetical protein 0.0173 0.0613 0.2376
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0032 0.0056 0.0126
Echinococcus granulosus WD repeat containing protein 48 0.0106 0.0349 0.0428
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0104 0.0127
Schistosoma mansoni multidrug resistance protein 0.0032 0.0056 0.0068
Brugia malayi chromobox protein homolog 3 0.0049 0.0126 0.029
Echinococcus granulosus ATP binding cassette sub family G 0.0029 0.0047 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.0202
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0191 0.0234
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0133 0.0309
Loa Loa (eye worm) hypothetical protein 0.0504 0.1921 0.4441
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0203
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0032 0.0056 0.0126
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.1143 0.1117
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0019 0.0008 0.0009
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.004 0.0088 0.0107
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0089 0.0235
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0025 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0156 0.0405
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0126 0.0154
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0108 0.0249
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0191 0.0234
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0173 0.0613 0.2376
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0082 0.0203
Entamoeba histolytica protein kinase, putative 0.003 0.005 0.0316
Loa Loa (eye worm) 6-phosphofructokinase 0.0211 0.0764 0.1766
Trypanosoma brucei Emopamil binding protein, putative 0.0282 0.1046 0.1024
Echinococcus granulosus adenylate cyclase 9 0.0075 0.0229 0.0281
Plasmodium falciparum eukaryotic initiation factor 4A 0.0025 0.003 0.0033
Brugia malayi Cyclic-nucleotide gated cation channel 0.0027 0.0037 0.0084
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0057 0.0156 0.0509
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0084 0.0103
Brugia malayi Kinesin motor domain containing protein 0.0027 0.0037 0.0084
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0103 0.0337 0.0413
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0829 0.3207 0.7415
Loa Loa (eye worm) TK protein kinase 0.0034 0.0064 0.0148
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.023
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0278 0.1028 0.3423
Schistosoma mansoni hypothetical protein 0.006 0.0169 0.0207
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0164 0.02
Schistosoma mansoni tyrosine kinase 0.0077 0.0234 0.0287
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0173 0.0613 0.0752
Brugia malayi Protein cec-1. 0.0023 0.002 0.0046
Echinococcus multilocularis lipoxygenase domain containing protein 0.008 0.0246 0.0301
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1955 0.5334
Schistosoma mansoni lipoxygenase 0.0412 0.1559 0.1915
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0031 0.0006
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0056 0.0026
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0173 0.0613 0.4539
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.0056 0.0107
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0082 0.019
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.004 0.0088 0.0107
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0088 0.0107
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.1331 0.3623
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0173 0.0613 0.1656
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0056 0.0068
Brugia malayi glutathione reductase 0.0766 0.2956 0.6833
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0505 0.0476
Loa Loa (eye worm) hypothetical protein 0.0152 0.0531 0.1227
Loa Loa (eye worm) hypothetical protein 0.0615 0.2361 0.5459
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0029 0.0047 0.0057
Schistosoma mansoni survival motor neuron protein 0.0049 0.0125 0.0152
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.0292 0.0358
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0052 0.0137 0.0374
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0037 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0203
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0082 0.01
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.002 0.0034
Echinococcus multilocularis sodium channel protein 0.0082 0.0255 0.0313
Brugia malayi 6-phosphofructokinase 0.0211 0.0766 0.1771
Loa Loa (eye worm) serotonin transporter b 0.0234 0.0856 0.1979
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.088 0.1081
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0025 0.003 0.0036
Trypanosoma brucei calmodulin 0.0025 0.003 0.0005
Echinococcus multilocularis lipoxygenase domain containing protein 0.008 0.0246 0.0301
Entamoeba histolytica P-glyco protein 6, putative 0.0032 0.0056 0.0361
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0046 0.0106
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0032 0.0056 0.0126
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0104 0.0284
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0056 0.0131
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0104 0.0284
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0211 0.0764 0.0736
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0103 0.0337 0.0413
Schistosoma mansoni neuropeptide receptor 0.0103 0.0337 0.0413
Plasmodium falciparum ABC transporter G family member 2 0.0029 0.0047 0.0091
Schistosoma mansoni tyrosine kinase 0.0037 0.0078 0.0095
Echinococcus multilocularis calmodulin 0.0025 0.003 0.0037
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0028 0.0042 0.0073
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0333 0.0769
Plasmodium vivax hypothetical protein, conserved 0.003 0.0049 0.0098
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0045 0.0108 0.0083
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0246 0.0651
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0027 0.0037 0.0045
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0173 0.0613 0.1656
Brugia malayi PHD-finger family protein 0.003 0.0049 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0126 0.0291
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.0056 0.0107
Loa Loa (eye worm) cytochrome P450 0.0032 0.0056 0.013
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0173 0.0613 0.2034
Schistosoma mansoni cpg binding protein 0.0031 0.0053 0.0064
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0027 0.0062
Echinococcus granulosus serotonin transporter 0.0234 0.0856 0.1051
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0084 0.0194
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0081 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.0056 0.0107
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0233 0.0203
Brugia malayi putative neuropeptide receptor 0.0103 0.0337 0.0778
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0252 0.0582
Plasmodium falciparum ferrodoxin reductase-like protein 0.0173 0.0613 0.2018
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.004 0.0088 0.0107
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0056 0.0068
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0103 0.0337 0.0413
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0103 0.0236
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0046 0.0106
Echinococcus granulosus dro:myosuppressin receptor 0.0103 0.0337 0.0413
Entamoeba histolytica phosphofructokinase, putative 0.0211 0.0764 0.5672
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0056 0.0131
Brugia malayi Inositol-1 0.0111 0.037 0.0855
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0084 0.0102
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0133 0.0457 0.3374
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0103 0.0337 0.0779
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0173 0.0613 0.2034
Onchocerca volvulus 0.008 0.0246 0.067
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0031 0.0037
Echinococcus multilocularis neuropeptides capa receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0323 0.0862
Echinococcus multilocularis insulin receptor 0.0047 0.0117 0.0143
Brugia malayi Dopamine receptor protein 2 0.0103 0.0337 0.0778
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1259 0.3427
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0082 0.01
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0478 0.1818 0.4202
Schistosoma mansoni hypothetical protein 0.007 0.0206 0.0252
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0053 0.0141 0.0172
Schistosoma mansoni opsin-like receptor 0.0103 0.0337 0.0413
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.065 0.2499 0.2481
Echinococcus granulosus rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Brugia malayi Cytochrome P450 family protein 0.0049 0.0125 0.0288
Brugia malayi protein-tyrosine kinase 0.0034 0.0064 0.0147
Echinococcus granulosus acetylcholinesterase 0.0066 0.0191 0.0234
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0019 0.0022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0033 0.0068
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0057 0.0156 0.0462
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0116 0.0389 0.0477
Brugia malayi Cytochrome P450 family protein 0.0051 0.0133 0.0307
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0025 0.0015
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0082 0.01
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0103 0.0337 0.0413
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0173 0.0613 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0133 0.0457 0.1231
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0226 0.0701
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0175 0.0405
Schistosoma mansoni hypothetical protein 0.0024 0.0027 0.0032
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Plasmodium falciparum phd finger protein, putative 0.003 0.0049 0.0098
Toxoplasma gondii hypothetical protein 0.004 0.0088 0.023
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0103 0.0337 0.0779
Echinococcus granulosus RUN 0.008 0.0246 0.0301
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0211 0.0764 0.2521
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0029 0.0047 0.0022
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0104 0.0262
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0031 0.0069
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0505 0.0481
Brugia malayi hypothetical protein 0.0236 0.0863 0.1995
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0103 0.0337 0.0413
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0125 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0031 0.0062
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0173 0.0613 0.0752
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0056 0.0131
Schistosoma mansoni hypothetical protein 0.003 0.0049 0.006
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0056 0.0068
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0175 0.0457
Brugia malayi bZIP transcription factor family protein 0.0085 0.0268 0.0619
Schistosoma mansoni hypothetical protein 0.0103 0.0337 0.0413
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.0067 0.0082
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0031 0.0053 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0114 0.038 0.102
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0082 0.01
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0265 0.0325
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0032 0.0056 0.0126
Loa Loa (eye worm) phosphatidylinositol 3 0.0133 0.0457 0.1058
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0103 0.0337 0.0413
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0046 0.0106
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2131 0.835 0.8346
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.019
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0095 0.0117
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0077
Brugia malayi hypothetical protein 0.0048 0.0122 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0037 0.0079
Giardia lamblia DINP protein human, muc B family 0.0041 0.0094 0.0258
Onchocerca volvulus 0.0103 0.0337 0.0919
Onchocerca volvulus 0.0049 0.0125 0.0339
Echinococcus granulosus sex peptide receptor 0.0103 0.0337 0.0413
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0175 0.0145
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0063 0.0077
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.002 0.0034
Brugia malayi hypothetical protein 0.008 0.0246 0.0567
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.002 0.0095
Echinococcus multilocularis expressed protein 0.0745 0.2872 0.3529
Plasmodium vivax SET domain protein, putative 0.012 0.0403 0.1304
Onchocerca volvulus 0.0103 0.0337 0.0919
Onchocerca volvulus 0.0103 0.0337 0.0919
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0046 0.0106
Giardia lamblia PHD finger protein 15 0.003 0.0049 0.0077
Loa Loa (eye worm) hypothetical protein 0.0234 0.0856 0.1979
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0103 0.0337 0.0413
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0024 0.0027 0.0007
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0282 0.1046 0.1019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Onchocerca volvulus 0.0103 0.0337 0.0919
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0082 0.0203
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0082 0.01
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0057 0.0156 0.0405
Trichomonas vaginalis inositol monophosphatase, putative 0.0111 0.037 0.0992
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0196 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.035 0.0936
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0037 0.0078 0.0095
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0173 0.0613 0.1415
Leishmania major hypothetical protein, conserved 0.0282 0.1046 0.1024
Plasmodium vivax thioredoxin reductase, putative 0.0766 0.2956 1
Onchocerca volvulus 0.0081 0.0252 0.0686
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0094 0.0236
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.0318 0.039
Echinococcus multilocularis neuropeptide s receptor 0.057 0.2184 0.2683
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0101 0.0072
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0333 0.0769
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.002 0.0095
Echinococcus multilocularis glutamate synthase 0.0173 0.0613 0.0752
Echinococcus granulosus 7TM GPCR rhodopsin 0.0103 0.0337 0.0413
Brugia malayi MH2 domain containing protein 0.0144 0.05 0.1156
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0173 0.0613 0.2034
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0156 0.0405
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.002 0.0024
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0292
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1852 0.7246 0.7239
Echinococcus granulosus biogenic amine 5HT receptor 0.0103 0.0337 0.0413
Brugia malayi Blistered cuticle protein 3 0.0145 0.0503 0.1163
Brugia malayi multidrug resistance protein 3 0.0032 0.0056 0.0128
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0045 0.0108 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0108 0.0273
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Trichomonas vaginalis hypothetical protein 0.0023 0.002 0.0034
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0082 0.01
Treponema pallidum NADH oxidase 0.065 0.2499 1
Echinococcus multilocularis fmrfamide receptor 0.0103 0.0337 0.0413
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0173 0.0613 0.0584
Toxoplasma gondii 6-phosphofructokinase 0.0057 0.0156 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0057 0.0156 0.0405
Trichomonas vaginalis taga, putative 0.0032 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0057 0.0156 0.0462
Echinococcus granulosus tumor protein p63 0.1346 0.5246 0.6445
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0019 0.0023
Trypanosoma brucei protein kinase, putative 0.0049 0.0126 0.0101
Brugia malayi Melatonin receptor type 1A 0.0103 0.0337 0.0778
Schistosoma mansoni hypothetical protein 0.0089 0.0281 0.0344
Loa Loa (eye worm) blistered cuticle protein 3 0.0145 0.0503 0.1164
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.0117 0.0143
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0027 0.0037 0.0045
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0101 0.0072
Loa Loa (eye worm) hypothetical protein 0.0569 0.2177 0.5033
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.003 0.0061
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0032 0.0056 0.0126
Plasmodium vivax calmodulin, putative 0.0025 0.003 0.0034
Schistosoma mansoni amine GPCR 0.0103 0.0337 0.0413
Brugia malayi Tachykinin-like peptides receptor 99D 0.0103 0.0337 0.0778
Schistosoma mansoni tyrosine kinase 0.0079 0.0241 0.0296
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0133 0.0457 0.0561
Trypanosoma cruzi hypothetical protein, conserved 0.0173 0.0613 0.0584
Brugia malayi SRC-1 0.0037 0.0078 0.018
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.065 0.2499 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0049 0.006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0164 0.0561
Schistosoma mansoni multidrug resistance protein 0.0032 0.0056 0.0068
Schistosoma mansoni opsin-like receptor 0.0103 0.0337 0.0413
Onchocerca volvulus 0.0282 0.1046 0.2858
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0389 0.1468 0.1803
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0082 0.01
Entamoeba histolytica phosphofructokinase, putative 0.0211 0.0764 0.5672
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.0078 0.0095
Mycobacterium ulcerans monoxygenase 0.0173 0.0613 0.2376
Brugia malayi hypothetical protein 0.0038 0.0082 0.0188
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0001 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0239 0.0292
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0058 0.0133
Echinococcus multilocularis fmrfamide receptor 0.0103 0.0337 0.0413
Schistosoma mansoni neuropeptide receptor 0.0103 0.0337 0.0413
Onchocerca volvulus 0.0234 0.0856 0.2337
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0175 0.0145
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0175 0.015
Echinococcus granulosus voltage gated potassium channel 0.0037 0.0077 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0072 0.0176
Loa Loa (eye worm) hypothetical protein 0.0173 0.0613 0.1417
Echinococcus multilocularis tyrosine protein kinase Srms 0.0034 0.0064 0.0078
Brugia malayi Thioredoxin reductase 0.0766 0.2956 0.6833
Brugia malayi Furin-like cysteine rich region family protein 0.0145 0.0505 0.1168
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0133 0.0457 0.0434
Trypanosoma brucei unspecified product 0.0024 0.0025 0.0000027249
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0032 0.0056 0.0129
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0265 0.0611
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0037 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0403 0.0495
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0022 0.005
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0088 0.0107
Echinococcus multilocularis ATP binding cassette sub family B 0.0031 0.0053 0.0065
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0057 0.0156 0.1112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0209 0.0757 0.2067
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0513 0.1955 0.452
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0034 0.0064 0.0078
Brugia malayi M-phase phosphoprotein, mpp8 0.0114 0.0381 0.088
Echinococcus granulosus fmrfamide receptor 0.0103 0.0337 0.0413
Schistosoma mansoni chromobox protein 0.0023 0.002 0.0024
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0133 0.0457 0.0429
Entamoeba histolytica hypothetical protein 0.0038 0.0082 0.0558
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.035 0.0936
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.004 0.0088 0.0255
Echinococcus multilocularis tumor protein p63 0.1346 0.5246 0.6445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0215 0.0568
Echinococcus multilocularis neuropeptide FF receptor 2 0.0103 0.0337 0.0413
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0502 0.0616
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0031 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.019
Loa Loa (eye worm) hypothetical protein 0.0075 0.0229 0.0529
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.065 0.2499 0.8445
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0032 0.0056 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0133 0.0457 0.1231
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0755 0.2915 0.986
Echinococcus multilocularis neuropeptide receptor 0.0103 0.0337 0.0413
Schistosoma mansoni kinesin eg-5 0.0027 0.0037 0.0045
Echinococcus multilocularis multidrug resistance protein 1 0.0032 0.0056 0.0068
Onchocerca volvulus Neuropeptide F receptor homolog 0.0103 0.0337 0.0919
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0085 0.0268 0.0329
Echinococcus granulosus rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Leishmania major hypothetical protein, conserved 0.0075 0.0226 0.0202
Echinococcus granulosus ubiquitin specific protease 41 0.0076 0.0233 0.0286
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0082 0.01
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.037 0.0346
Echinococcus multilocularis ubiquitin specific protease 41 0.0076 0.0233 0.0286
Loa Loa (eye worm) hypothetical protein 0.0075 0.0226 0.0523
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0032 0.0056 0.0031
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Plasmodium falciparum flap endonuclease 1 0.0025 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0115 0.0385 0.1032
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0191 0.0234
Brugia malayi hypothetical protein 0.008 0.0246 0.0567
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0196 0.0166
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0198
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0056 0.0131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0046 0.0106
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0085
Echinococcus granulosus Chromo domain 0.0023 0.002 0.0024
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0082 0.01
Trichomonas vaginalis abcb9, putative 0.0032 0.0056 0.0131
Loa Loa (eye worm) hypothetical protein 0.1113 0.4325 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.0333 0.077
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0067 0.0154
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0233 0.0203
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0067 0.0144
Onchocerca volvulus 0.004 0.0088 0.0239
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0126 0.0343
Schistosoma mansoni chromobox protein 0.0023 0.002 0.0024
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0032 0.0056 0.0126
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0133 0.0457 0.0434
Echinococcus multilocularis Chromo domain 0.0023 0.002 0.0024
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.065 0.2499 0.307
Loa Loa (eye worm) hypothetical protein 0.0038 0.0082 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0126 0.0324
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0403 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0081 0.0056
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0164 0.02
Brugia malayi ORL1-like opioid receptor 0.0103 0.0337 0.0778
Brugia malayi manba-prov protein 0.0082 0.0254 0.0586
Entamoeba histolytica hypothetical protein 0.0038 0.0082 0.0558
Echinococcus granulosus lamin 0.0081 0.0252 0.0309
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0056 0.0026
Brugia malayi hypothetical protein 0.0067 0.0196 0.0451
Brugia malayi sulfakinin receptor protein 0.0103 0.0337 0.0778
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0056 0.0131
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0412 0.1559 0.1915
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0091 0.0292 0.0358
Entamoeba histolytica hypothetical protein 0.0102 0.0332 0.2433
Schistosoma mansoni biogenic amine (5HT) receptor 0.0346 0.1296 0.1592
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0046 0.0106
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0078 0.0095
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0089 0.024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0088
Toxoplasma gondii hypothetical protein 0.004 0.0088 0.023
Schistosoma mansoni tyrosine kinase 0.0047 0.0117 0.0143
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0056 0.0068
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.065 0.2499 0.8445
Echinococcus multilocularis neuropeptide Y receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0027 0.0037 0.0045
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0103 0.0337 0.0413
Mycobacterium leprae putative cytochrome p450 0.0032 0.0056 0.0108
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0126 0.0388
Schistosoma mansoni calmodulin 0.0025 0.003 0.0037
Schistosoma mansoni tyrosine kinase 0.0077 0.0234 0.0287
Trypanosoma brucei calmodulin 0.0025 0.003 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0034 0.0072
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.0241 0.0296
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0082 0.01
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0064 0.0078
Onchocerca volvulus 0.008 0.0246 0.067
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0032 0.0056 0.0121
Trichomonas vaginalis set domain proteins, putative 0.0944 0.3659 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0103 0.0337 0.0413
Toxoplasma gondii target of rapamycin (TOR), putative 0.0099 0.0323 0.1029
Echinococcus multilocularis g-protein coupled receptor 0.0103 0.0337 0.0413
Brugia malayi FAT domain containing protein 0.0019 0.0008 0.0017
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.002 0.0024
Brugia malayi RE15519p 0.0103 0.0337 0.0778
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0088 0.0107
Echinococcus multilocularis lamin 0.0081 0.0252 0.0309
Echinococcus granulosus chromobox protein 1 0.0079 0.0243 0.0298
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0077 0.0094
Echinococcus multilocularis g protein coupled receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0095 0.0117
Brugia malayi Heterochromatin protein 1 0.0079 0.0243 0.0561
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0265 0.0325
Echinococcus granulosus calmodulin 0.0025 0.003 0.0037
Trypanosoma brucei unspecified product 0.0055 0.0148 0.0124
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0604 0.2317 0.2846
Schistosoma mansoni disulfide oxidoreductase 0.0173 0.0613 0.0752
Echinococcus granulosus tm gpcr rhodopsin 0.0604 0.2317 0.2846
Trypanosoma brucei calmodulin 0.0025 0.003 0.0005
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0196 0.1413
Loa Loa (eye worm) hypothetical protein 0.0051 0.0134 0.0309
Echinococcus multilocularis adenylate cyclase 9 0.0075 0.0229 0.0281
Brugia malayi cytochrome P450 0.0032 0.0056 0.0129
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0056 0.0131
Loa Loa (eye worm) helicase 0.0023 0.002 0.0047
Echinococcus granulosus neuropeptide receptor 0.0103 0.0337 0.0413
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0191 0.0234
Loa Loa (eye worm) hypothetical protein 0.0025 0.003 0.007
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1955 0.5334
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0114 0.0383 0.047
Loa Loa (eye worm) neuropeptide F receptor 0.0103 0.0337 0.0779
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2549 1 1
Onchocerca volvulus 0.0173 0.0613 0.1673
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0126 0.0154
Schistosoma mansoni alpha-1 adrenergic receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0242 0.0642
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0088 0.0202
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0115 0.0385 0.1032
Schistosoma mansoni tyrosine kinase 0.0047 0.0117 0.0143
Echinococcus granulosus g protein coupled receptor 0.0103 0.0337 0.0413
Schistosoma mansoni polycystin 1-related 0.008 0.0246 0.0301
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0389 0.1468 0.3394
Loa Loa (eye worm) hypothetical protein 0.0234 0.0856 0.1979
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0082 0.0203
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.0056 0.0107
Schistosoma mansoni glutamate synthase 0.0173 0.0613 0.0752
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0164 0.0377
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0173 0.0613 0.0589
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0173 0.0613 0.2018
Echinococcus granulosus histone lysine methyltransferase setb 0.012 0.0403 0.0495
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0081 0.0186
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0133 0.0457 0.0561
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0025 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Echinococcus multilocularis ATP binding cassette sub family G 0.0029 0.0047 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0052 0.0027
Echinococcus multilocularis dnaJ subfamily B 0.0416 0.1573 0.1932
Brugia malayi calmodulin 0.0025 0.003 0.0069
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Trypanosoma cruzi NADH dehydrogenase, putative 0.0173 0.0613 0.0584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.023 0.0281
Leishmania major eukaryotic initiation factor 4a, putative 0.0025 0.003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0103 0.0337 0.0413
Loa Loa (eye worm) hypothetical protein 0.0076 0.0233 0.0539
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Plasmodium falciparum thioredoxin reductase 0.0766 0.2956 1
Echinococcus multilocularis peregrin 0.0034 0.0064 0.0077
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0058 0.0071
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.0241 0.0296
Loa Loa (eye worm) hypothetical protein 0.0389 0.1468 0.3394
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0173 0.0613 0.0752
Echinococcus granulosus dna polymerase eta 0.0034 0.0067 0.0082
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0173 0.0613 0.2359
Schistosoma mansoni rab6-interacting 0.008 0.0246 0.0301
Brugia malayi phosphofructokinase 0.0211 0.0764 0.1765
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0173 0.0613 0.2376
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0037 0.0045
Echinococcus multilocularis sex peptide receptor 0.0103 0.0337 0.0413
Entamoeba histolytica P-glycoprotein-2 0.0032 0.0056 0.0361
Loa Loa (eye worm) glycosyl hydrolase family 2 0.024 0.088 0.2035
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0082 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0037 0.0079
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0278 0.1028 0.3423
Brugia malayi CXXC zinc finger family protein 0.0029 0.0046 0.0106
Loa Loa (eye worm) hypothetical protein 0.0077 0.0235 0.0543
Schistosoma mansoni tyrosine kinase 0.0037 0.0078 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0016 0.0018
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0103 0.0238
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2131 0.835 0.8345
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0029 0.0047 0.0017
Echinococcus multilocularis WD repeat containing protein 48 0.0106 0.0349 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0082 0.0203
Schistosoma mansoni cellular tumor antigen P53 0.0197 0.0709 0.087
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0126 0.0323
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0206 0.0475
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0037 0.0045
Brugia malayi hypothetical protein 0.0103 0.0337 0.0778
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0111 0.037 0.1396
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0057 0.0156 0.053
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1955 0.5334
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0049 0.0114
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0032 0.0056 0.0126
Schistosoma mansoni cpg binding protein 0.0031 0.0053 0.0064
Schistosoma mansoni hypothetical protein 0.0103 0.0337 0.0413
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0046 0.0107
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0082 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0031 0.0037
Loa Loa (eye worm) hypothetical protein 0.0504 0.1921 0.4441
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0103 0.0337 0.0779
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0148 0.0342
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0173 0.0613 0.2006
Loa Loa (eye worm) hypothetical protein 0.0206 0.0744 0.1721
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0755 0.2915 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0076 0.0233 0.0286
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0173 0.0613 0.2018
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0126 0.0154
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0164 0.02
Schistosoma mansoni flap endonuclease-1 0.0023 0.0021 0.0025
Onchocerca volvulus 0.0103 0.0337 0.0919
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0203
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0233 0.0286
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0905 0.3504 0.4306
Echinococcus granulosus tyrosine kinase 0.0034 0.0064 0.0078
Plasmodium vivax ABC transporter G family member 2, putative 0.0029 0.0047 0.0091
Onchocerca volvulus 0.0032 0.0056 0.0151
Trichomonas vaginalis mercuric reductase, putative 0.065 0.2499 0.6823
Loa Loa (eye worm) hypothetical protein 0.0152 0.053 0.1227
Schistosoma mansoni amine GPCR 0.0584 0.2237 0.2749
Loa Loa (eye worm) hypothetical protein 0.0038 0.0081 0.0187
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0031 0.0174
Schistosoma mansoni lipoxygenase 0.0269 0.0992 0.1219
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0125 0.0289
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.002 0.0024
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0111 0.037 0.1396
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0082 0.01
Brugia malayi jmjC domain containing protein 0.0038 0.0081 0.0185
Trichomonas vaginalis chromobox protein, putative 0.0052 0.0137 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0323 0.0862
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0027 0.0037 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0042 0.0093
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0031 0.0071
Echinococcus granulosus calmodulin 0.0025 0.003 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0082 0.0203
Entamoeba histolytica hypothetical protein 0.0025 0.0031 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0133 0.0457 0.1231
Schistosoma mansoni smdr2 0.0032 0.0056 0.0068
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0175 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1955 0.5334
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0084 0.0102
Brugia malayi G-protein coupled receptor 0.0103 0.0337 0.0778
Echinococcus granulosus calmodulin 0.0025 0.003 0.0037
Echinococcus granulosus tyrosine protein kinase Src42A 0.0037 0.0078 0.0095
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0076 0.0233 0.169
Loa Loa (eye worm) hypothetical protein 0.0038 0.008 0.0185
Loa Loa (eye worm) hypothetical protein 0.0346 0.1296 0.2997
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0103 0.0337 0.0779
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.0067 0.0446
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.037 0.0346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0031 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0018
Leishmania major cytochrome p450-like protein 0.0049 0.0125 0.0101
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0088 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0175 0.0145
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.065 0.2499 0.8445
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0084 0.0102
Schistosoma mansoni hypothetical protein 0.0045 0.0111 0.0135
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0175 0.0457
Echinococcus granulosus rhodopsin orphan GPCR 0.0103 0.0337 0.0413
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0019 0.0022
Echinococcus granulosus neuropeptide receptor A26 0.057 0.2184 0.2683
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.0056 0.0107
Echinococcus multilocularis tyrosine protein kinase Blk 0.0034 0.0064 0.0078
Echinococcus multilocularis calmodulin 0.0025 0.003 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0211 0.0764 0.207
Schistosoma mansoni hypothetical protein 0.008 0.0246 0.0301
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0173 0.0613 0.2006
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0111 0.037 0.1192
Schistosoma mansoni hypothetical protein 0.0103 0.0337 0.0413
Schistosoma mansoni neuropeptide receptor 0.0103 0.0337 0.0413
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1955 0.5334
Trichomonas vaginalis apoptosis inducing factor, putative 0.0173 0.0613 0.1656

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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