TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 279.333 | Formula: C18H17NO2
H donors: 0 H acceptors: 1 LogP: 2.79 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: CN(Cc1cc(=O)oc2c1cccc2)Cc1ccccc1
InChi: 1S/C18H17NO2/c1-19(12-14-7-3-2-4-8-14)13-15-11-18(20)21-17-10-6-5-9-16(15)17/h2-11H,12-13H2,1H3
InChiKey: IHQCJCALZYMEJH-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0167	0.1918	0.9872
Leishmania major	serine/threonine protein phosphatase 2B catalytic subunit A2, putative	0.0041	0.0289	0.5429
Schistosoma mansoni	intermediate filament proteins	0.0053	0.0443	0.104
Echinococcus multilocularis	serine:threonine protein phosphatase 2B	0.0041	0.0289	0.0288
Schistosoma mansoni	hypothetical protein	0.0349	0.425	1
Trypanosoma brucei	PAB1-binding protein , putative	0.0028	0.0129	0.4018
Mycobacterium ulcerans	3-oxoacyl-ACP reductase	0.0039	0.0265	0.0369
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0039	0.0265	0.1364
Echinococcus granulosus	Mitotic checkpoint protein PRCC C terminal	0.0141	0.1579	0.3714
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0786	0.4042
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0532	0.0743
Loa Loa (eye worm)	hypothetical protein	0.0024	0.008	0.0406
Echinococcus multilocularis	GPCR, family 2	0.0037	0.0238	0.0237
Schistosoma mansoni	lamin	0.0053	0.0443	0.104
Mycobacterium leprae	NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE)	0.0573	0.714	1
Mycobacterium tuberculosis	Possible oxidoreductase	0.0039	0.0265	0.0369
Loa Loa (eye worm)	transcription factor SMAD2	0.0144	0.162	0.8338
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0152	0.1725	0.1724
Wolbachia endosymbiont of Brugia malayi	Short-chain alcohol dehydrogenase family enzyme	0.0039	0.0265	0.0369
Loa Loa (eye worm)	TAR-binding protein	0.0124	0.1359	0.6994
Brugia malayi	exodeoxyribonuclease III family protein	0.0018	0.0001	0.0006
Leishmania major	serine/threonine protein phosphatase, putative	0.0041	0.0289	0.5429
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0124	0.1359	0.6994
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0025	0.0093	0.0215
Brugia malayi	RNA recognition motif domain containing protein	0.0124	0.1359	0.6996
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.006	0.0532	0.1249
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0037	0.0238	0.1219
Leishmania major	hypothetical protein, conserved	0.0028	0.0129	0.2402
Echinococcus multilocularis	3 oxoacyl acyl carrier protein reductase	0.0039	0.0265	0.0264
Trypanosoma cruzi	serine/threonine protein phosphatase, putative	0.0041	0.0289	0.9082
Schistosoma mansoni	hypothetical protein	0.0037	0.0238	0.0557
Brugia malayi	hypothetical protein	0.0169	0.1943	1
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0024	0.008	0.0406
Echinococcus multilocularis	muscleblind protein	0.0167	0.1918	0.1917
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Onchocerca volvulus		0.0043	0.0318	0.0319
Onchocerca volvulus		0.0053	0.0443	0.1062
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0116	0.1258	0.6474
Loa Loa (eye worm)	hypothetical protein	0.0167	0.1918	0.9872
Plasmodium falciparum	enoyl-acyl carrier reductase	0.0573	0.714	1
Trichomonas vaginalis	hypothetical protein	0.0573	0.714	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0079	0.0786	0.4046
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0025	0.0093	0.0091
Brugia malayi	RNA binding protein	0.0124	0.1359	0.6996
Trypanosoma cruzi	PAB1-binding protein , putative	0.0028	0.0129	0.4018
Toxoplasma gondii	2,4-dienoyl CoA reductase 2, peroxisomal family protein	0.0043	0.0318	0.0444
Mycobacterium ulcerans	oxidoreductase	0.0039	0.0265	0.0369
Mycobacterium tuberculosis	Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase)	0.0039	0.0265	0.0369
Echinococcus multilocularis	Mitotic checkpoint protein PRCC, C terminal	0.0141	0.1579	0.1578
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Brugia malayi	Intermediate filament tail domain containing protein	0.0053	0.0443	0.2281
Mycobacterium tuberculosis	Probable oxidoreductase	0.0043	0.0318	0.0444
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0143	0.1602	0.3767
Trypanosoma cruzi	beta-ketoacyl-ACP reductase	0.0039	0.0265	0.8314
Brugia malayi	intermediate filament protein	0.0053	0.0443	0.2281
Entamoeba histolytica	calcineurin catalytic subunit A, putative	0.0041	0.0289	1
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0028	0.0129	0.0655
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.1359	0.3195
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0116	0.1258	0.6477
Loa Loa (eye worm)	3-hydroxyacyl-CoA dehydrogenase type II	0.0039	0.0265	0.1358
Loa Loa (eye worm)	hypothetical protein	0.004	0.0282	0.1446
Loa Loa (eye worm)	retinol dehydrogenase 12	0.0039	0.0265	0.1358
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0018	0.0001	0.5
Entamoeba histolytica	calcineurin catalytic subunit A, putative	0.0041	0.0289	1
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Echinococcus multilocularis	lamin	0.0053	0.0443	0.0442
Entamoeba histolytica	calcineurin catalytic subunit A, putative	0.0041	0.0289	1
Plasmodium falciparum	serine/threonine protein phosphatase 2B catalytic subunit A	0.0041	0.0289	0.0404
Mycobacterium tuberculosis	Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase)	0.0039	0.0265	0.0369
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.006	0.0532	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0431	0.2212
Schistosoma mansoni	3-oxoacyl-[ACP] reductase	0.0039	0.0265	0.0621
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0043	0.0318	0.0444
Toxoplasma gondii	enoyl-acyl carrier reductase ENR	0.0573	0.714	1
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0039	0.0265	0.1364
Mycobacterium ulcerans	3-oxoacyl-ACP reductase	0.0039	0.0265	0.0369
Trypanosoma brucei	beta-ketoacyl-ACP reductase	0.0039	0.0265	0.8314
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0143	0.1602	0.1601
Brugia malayi	hypothetical protein	0.0028	0.0129	0.0663
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.1359	0.3195
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0037	0.0238	0.0237
Mycobacterium ulcerans	3-ketoacyl-ACP reductase	0.0039	0.0265	0.0369
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0037	0.0238	0.1224
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0043	0.0318	0.0444
Echinococcus multilocularis	musashi	0.0053	0.0443	0.0442
Onchocerca volvulus		0.0053	0.0443	0.1062
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0532	0.0743
Loa Loa (eye worm)	RNA binding protein	0.0124	0.1359	0.6994
Trypanosoma cruzi	oxidoreductase-like protein, putative	0.0043	0.0318	1
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.1359	0.3195
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0532	0.0743
Echinococcus multilocularis	geminin	0.0349	0.425	0.425
Echinococcus granulosus	tar DNA binding protein	0.0124	0.1359	0.3195
Wolbachia endosymbiont of Brugia malayi	enoyl-ACP reductase	0.0573	0.714	1
Leishmania major	oxidoreductase-like protein	0.0043	0.0318	0.5978
Echinococcus granulosus	GPCR family 2	0.0037	0.0238	0.0557
Echinococcus multilocularis	tar DNA binding protein	0.0124	0.1359	0.1358
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0265	0.1358
Mycobacterium tuberculosis	Probable dehydrogenase/reductase	0.0039	0.0265	0.0369
Onchocerca volvulus		0.0169	0.1943	1
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Mycobacterium tuberculosis	Possible oxidoreductase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	3-alpha-hydroxysteroid dehydrogenase	0.0043	0.0318	0.0444
Entamoeba histolytica	Ser/Thr protein phosphatase, putative	0.0041	0.0289	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0116	0.1258	0.6477
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.006	0.0532	1
Toxoplasma gondii	short chain dehydrogenase family protein, putative	0.0039	0.0265	0.0369
Trypanosoma brucei	pteridine reductase 1	0.0039	0.0265	0.8314
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.0532	0.1249
Mycobacterium ulcerans	20-beta-hydroxysteroid dehydrogenase FabG3	0.0039	0.0265	0.0369
Echinococcus granulosus	3 oxoacyl acyl carrier protein reductase	0.0039	0.0265	0.0621
Chlamydia trachomatis	enoyl-acyl-carrier protein reductase	0.0573	0.714	1
Mycobacterium ulcerans	enoyl-(acyl carrier protein) reductase	0.0573	0.714	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0143	0.1602	0.3767
Echinococcus granulosus	muscleblind protein	0.0167	0.1918	0.451
Brugia malayi	cytoplasmic intermediate filament protein	0.0028	0.0129	0.0662
Brugia malayi	TAR-binding protein	0.0124	0.1359	0.6996
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Trypanosoma cruzi	beta-ketoacyl-ACP reductase	0.0039	0.0265	0.8314
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0143	0.1602	0.3767
Schistosoma mansoni	hypothetical protein	0.0349	0.425	1
Brugia malayi	Serine/threonine protein phosphatase 2B catalytic subunit 2	0.0041	0.0289	0.1489
Trypanosoma cruzi	PAB1-binding protein , putative	0.0028	0.0129	0.4018
Loa Loa (eye worm)	intermediate filament protein	0.0053	0.0443	0.2276
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Schistosoma mansoni	hypothetical protein	0.0079	0.0786	0.1847
Toxoplasma gondii	aldehyde dehydrogenase	0.006	0.0532	0.0743
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0443	0.2276
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0053	0.0443	0.2276
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0143	0.1602	0.1601
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Trypanosoma cruzi	serine/threonine protein phosphatase 2B catalytic subunit A2, putative	0.0041	0.0289	0.9082
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	short chain dehydrogenase	0.0043	0.0318	0.0444
Leishmania major	pteridine reductase 1	0.0043	0.0318	0.5978
Toxoplasma gondii	protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein	0.0041	0.0289	0.0404
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Loa Loa (eye worm)	oxidoreductase	0.0039	0.0265	0.1358
Leishmania major	dehydrogenase/oxidoreductase-like protein	0.0039	0.0265	0.497
Brugia malayi	Latrophilin receptor protein 2	0.0037	0.0238	0.1224
Schistosoma mansoni	hypothetical protein	0.0037	0.0238	0.0557
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0143	0.1602	0.3767
Plasmodium vivax	3-oxoacyl-[acyl-carrier-protein] reductase, putative	0.0039	0.0265	0.0369
Schistosoma mansoni	thyroid hormone receptor	0.0152	0.1725	0.4057
Schistosoma mansoni	thyroid hormone receptor	0.0152	0.1725	0.4057
Toxoplasma gondii	LsmAD domain-containing protein	0.0028	0.0129	0.0179
Entamoeba histolytica	Ser/Thr protein phosphatase, putative	0.0041	0.0289	1
Leishmania major	dehydrogenase/oxidoreductase-like protein	0.0039	0.0265	0.497
Plasmodium vivax	ataxin-2 like protein, putative	0.0028	0.0129	0.0179
Echinococcus granulosus	lamin	0.0053	0.0443	0.104
Loa Loa (eye worm)	MH2 domain-containing protein	0.0144	0.162	0.8338
Echinococcus granulosus	geminin	0.0349	0.425	1
Plasmodium falciparum	3-oxoacyl-[acyl-carrier-protein] reductase	0.0039	0.0265	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0169	0.1943	1
Schistosoma mansoni	hypothetical protein	0.0037	0.0238	0.0557
Plasmodium vivax	enoyl-acyl carrier protein reductase	0.0573	0.714	1
Echinococcus multilocularis	lamin dm0	0.0053	0.0443	0.0442
Schistosoma mansoni	lamin	0.0053	0.0443	0.104
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0037	0.0238	0.0557
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.1359	0.3195
Plasmodium falciparum	ataxin-2 like protein, putative	0.0028	0.0129	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0116	0.1258	0.6474
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.1359	0.3195
Trypanosoma brucei	protein phosphatase 2B, putative	0.0041	0.0289	0.9082
Loa Loa (eye worm)	hypothetical protein	0.0037	0.0238	0.1219
Schistosoma mansoni	protein phosphatase-2b	0.0041	0.0289	0.0678
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	3-ketoacyl-ACP reductase	0.0039	0.0265	0.0369
Schistosoma mansoni	protein phosphatase-2b	0.0041	0.0289	0.0678
Plasmodium falciparum	ataxin-2 like protein, putative	0.0028	0.0129	0.0179
Mycobacterium tuberculosis	NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase)	0.0573	0.714	1
Echinococcus granulosus	serine:threonine protein phosphatase 2B	0.0041	0.0289	0.0678
Mycobacterium ulcerans	3-ketoacyl-ACP reductase	0.0039	0.0265	0.0369
Brugia malayi	Muscleblind-like protein	0.0167	0.1918	0.9872
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0143	0.1602	0.8244
Trypanosoma cruzi	serine/threonine protein phosphatase, putative	0.0041	0.0289	0.9082
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0289	0.1484
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0143	0.1602	0.3767
Mycobacterium ulcerans	3-ketoacyl-ACP reductase	0.0039	0.0265	0.0369
Toxoplasma gondii	3-ketoacyl-(acyl-carrier-protein) reductase	0.0039	0.0265	0.0369
Schistosoma mansoni	hypothetical protein	0.0141	0.1579	0.3714
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0037	0.0238	0.0237
Schistosoma mansoni	hypothetical protein	0.0037	0.0238	0.0557
Echinococcus multilocularis	muscleblind protein 1	0.0167	0.1918	0.1917
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0018	0.0001	0.5
Plasmodium vivax	serine/threonine protein phosphatase 2B catalytic subunit A, putative	0.0041	0.0289	0.0404
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0129	0.0657
Leishmania major	3-oxoacyl-ACP reductase, putative	0.0039	0.0265	0.497
Echinococcus multilocularis	serine:threonine protein phosphatase 2B	0.0041	0.0289	0.0288
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	3-ketoacyl-ACP reductase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0039	0.0265	0.0369
Mycobacterium ulcerans	short chain dehydrogenase	0.0039	0.0265	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0093	0.047
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.0532	0.1249
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.006	0.0532	0.0743
Echinococcus granulosus	lamin dm0	0.0053	0.0443	0.104
Echinococcus granulosus	intermediate filament protein	0.0053	0.0443	0.104
Trypanosoma brucei	oxidoreductase-like protein	0.0043	0.0318	1
Entamoeba histolytica	calcineurin catalytic subunit A, putative	0.0041	0.0289	1
Schistosoma mansoni	dihydropteridine reductase	0.0039	0.0265	0.0621
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0037	0.0238	0.0557
Brugia malayi	MH2 domain containing protein	0.0144	0.162	0.834
Echinococcus granulosus	serine:threonine protein phosphatase 2B	0.0041	0.0289	0.0678
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0143	0.1602	0.8245
Entamoeba histolytica	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0039	0.0265	0.9155

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	15.775 uM	PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249]	ChEMBL.	No reference
Potency (functional)	22.3872 uM	PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1900689

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1539163