Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | sodium channel protein | 0.0081 | 0.1113 | 0.1113 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0388 | 0.6469 | 0.6469 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | embryonic ectoderm development protein | 0.0096 | 0.1369 | 0.1369 |
Echinococcus granulosus | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Brugia malayi | Cation transporter family protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0109 | 0.1611 | 0.249 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0388 | 0.6469 | 0.6469 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0183 | 0.2893 | 0.4472 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1611 | 0.249 |
Echinococcus multilocularis | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0183 | 0.2893 | 0.2893 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0388 | 0.6469 | 0.6469 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | steroid hormone receptor | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.081 | 0.081 |
Loa Loa (eye worm) | ACC-1 protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Schistosoma mansoni | coup transcription factor | 0.0388 | 0.6469 | 0.6469 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0183 | 0.2893 | 0.4451 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0183 | 0.2893 | 0.2893 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0019 | 0.0025 | 0.0038 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0051 | 0.0596 | 0.0922 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0023 | 0.0094 | 0.0146 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0023 | 0.0094 | 0.0094 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0023 | 0.0094 | 0.0094 |
Brugia malayi | nuclear hormone receptor | 0.0183 | 0.2893 | 0.4472 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | DR-78 | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | hypothetical protein | 0.0077 | 0.1052 | 0.1627 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0183 | 0.2893 | 0.2893 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0019 | 0.0025 | 0.0025 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0019 | 0.0025 | 0.0025 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0023 | 0.0094 | 0.0094 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | ae-1 binding protein aebp2 | 0.059 | 1 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0596 | 0.0596 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0023 | 0.0094 | 0.0146 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0038 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0388 | 0.6469 | 0.6469 |
Echinococcus multilocularis | polycomb protein suz12 A | 0.0328 | 0.542 | 0.542 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.081 | 0.081 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.1636 | 0.1636 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0388 | 0.6469 | 1 |
Onchocerca volvulus | 0.0023 | 0.0094 | 0.0108 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0162 | 0.2532 | 0.3914 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.081 | 0.081 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.081 | 0.1252 |
Schistosoma mansoni | nuclear receptor | 0.0183 | 0.2893 | 0.2893 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0023 | 0.0094 | 0.0094 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0388 | 0.6469 | 0.6469 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0388 | 0.6469 | 1 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.081 | 0.081 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0023 | 0.0094 | 0.0094 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | nuclear receptor RXR | 0.0205 | 0.3276 | 0.5064 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0183 | 0.2893 | 0.2893 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.3276 | 0.5064 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0111 | 0.1636 | 0.2529 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Echinococcus multilocularis | histone lysine N methyltransferase E(z) | 0.0283 | 0.4645 | 0.4645 |
Onchocerca volvulus | 0.0023 | 0.0094 | 0.0108 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0183 | 0.2893 | 0.4451 |
Schistosoma mansoni | thyroid hormone receptor | 0.0388 | 0.6469 | 0.6469 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0183 | 0.2893 | 0.2893 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0388 | 0.6469 | 0.6469 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0183 | 0.2893 | 0.2893 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0388 | 0.6469 | 0.6469 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0038 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0252 | 0.4099 | 0.6336 |
Onchocerca volvulus | 0.0388 | 0.6469 | 1 | |
Brugia malayi | SET domain containing protein | 0.0283 | 0.4645 | 0.718 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | LGC-31 protein | 0.0023 | 0.0094 | 0.0146 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0183 | 0.2893 | 0.2893 |
Echinococcus multilocularis | polycomb protein EED | 0.0096 | 0.1369 | 0.1369 |
Brugia malayi | WD domain containing protein | 0.0096 | 0.1369 | 0.2117 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0109 | 0.1611 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1052 | 0.1627 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0109 | 0.1611 | 0.249 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0183 | 0.2893 | 0.2893 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0038 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0109 | 0.1611 | 0.249 |
Loa Loa (eye worm) | WD domain-containing protein | 0.0096 | 0.1369 | 0.2117 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0388 | 0.6469 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0205 | 0.3276 | 0.5064 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0388 | 0.6469 | 0.6469 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0388 | 0.6469 | 0.6469 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.3276 | 0.5064 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0252 | 0.4099 | 0.6336 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.3276 | 0.5064 |
Loa Loa (eye worm) | ACC-1 protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0596 | 0.0596 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0019 | 0.0025 | 0.0025 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0388 | 0.6469 | 0.6469 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0388 | 0.6469 | 0.6469 |
Onchocerca volvulus | 0.0183 | 0.2893 | 0.4451 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | enhancer of zeste ezh | 0.0283 | 0.4645 | 0.4645 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0183 | 0.2893 | 0.4472 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0109 | 0.1611 | 0.1611 |
Onchocerca volvulus | 0.0109 | 0.1611 | 0.2461 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0388 | 0.6469 | 0.6469 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0038 | 0.5 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0023 | 0.0094 | 0.0094 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0023 | 0.0094 | 0.0094 |
Echinococcus multilocularis | serotonin transporter | 0.0109 | 0.1611 | 0.1611 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0388 | 0.6469 | 0.6469 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0205 | 0.3276 | 0.5064 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0023 | 0.0094 | 0.0094 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0388 | 0.6469 | 0.6469 |
Brugia malayi | conserved hypotetical protein | 0.0183 | 0.2893 | 0.4472 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0023 | 0.0094 | 0.0094 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.081 | 0.081 |
Onchocerca volvulus | 0.0183 | 0.2893 | 0.4451 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0205 | 0.3276 | 0.3276 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0019 | 0.0025 | 0.0038 |
Brugia malayi | nuclear receptor NHR-88 | 0.0183 | 0.2893 | 0.4472 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0388 | 0.6469 | 0.6469 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0023 | 0.0094 | 0.0094 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.1636 | 0.2529 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0388 | 0.6469 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0596 | 0.0596 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0183 | 0.2893 | 0.4472 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0081 | 0.1113 | 0.1113 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0205 | 0.3276 | 0.3276 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0183 | 0.2893 | 0.4472 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.3276 | 0.5064 |
Echinococcus granulosus | GPCR family 2 | 0.0051 | 0.0596 | 0.0596 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0109 | 0.1611 | 0.1611 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0038 | 0.0038 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0388 | 0.6469 | 1 |
Echinococcus granulosus | serotonin transporter | 0.0109 | 0.1611 | 0.1611 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0038 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0596 | 0.0596 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0388 | 0.6469 | 0.6469 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0019 | 0.0025 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0388 | 0.6469 | 1 |
Brugia malayi | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | Cation transporter family protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0038 | 0.0038 |
Brugia malayi | MH2 domain containing protein | 0.0252 | 0.4099 | 0.6336 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0328 | 0.542 | 0.542 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0081 | 0.1113 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0596 | 0.0596 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0388 | 0.6469 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0023 | 0.0094 | 0.0094 |
Onchocerca volvulus | Putative nachr subunit | 0.0023 | 0.0094 | 0.0108 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0183 | 0.2893 | 0.2893 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0205 | 0.3276 | 0.3276 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0038 | 0.5 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | nuclear hormone receptor | 0.0183 | 0.2893 | 0.2893 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.081 | 0.1252 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0094 | 0.0146 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0019 | 0.0025 | 0.0025 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0038 | 0.0038 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0388 | 0.6469 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0051 | 0.0596 | 0.0596 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | tailless protein | 0.0183 | 0.2893 | 0.4472 |
Echinococcus granulosus | FTZ F1 alpha | 0.0388 | 0.6469 | 0.6469 |
Echinococcus granulosus | polycomb protein EED | 0.0096 | 0.1369 | 0.1369 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.2532 | 0.3914 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0023 | 0.0094 | 0.0146 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0038 | 0.0038 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Onchocerca volvulus | 0.0023 | 0.0094 | 0.0108 | |
Onchocerca volvulus | Bile acid receptor homolog | 0.0388 | 0.6469 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0388 | 0.6469 | 0.6469 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0019 | 0.0025 | 0.0038 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0038 | 1 |
Onchocerca volvulus | 0.0023 | 0.0094 | 0.0108 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0183 | 0.2893 | 0.2893 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0038 | 0.5 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | RNA binding protein | 0.0064 | 0.081 | 0.1252 |
Schistosoma mansoni | nuclear hormone receptor | 0.0388 | 0.6469 | 0.6469 |
Brugia malayi | nuclear hormone receptor | 0.0388 | 0.6469 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0205 | 0.3276 | 0.5064 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0183 | 0.2893 | 0.2893 |
Brugia malayi | Cation transporter family protein | 0.0023 | 0.0094 | 0.0146 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1611 | 0.249 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0038 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0388 | 0.6469 | 0.6469 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.081 | 0.1252 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.081 | 0.1252 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0038 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0596 | 0.0596 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0388 | 0.6469 | 0.6469 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0162 | 0.2532 | 0.3914 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.081 | 0.081 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0388 | 0.6469 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0183 | 0.2893 | 0.4472 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0388 | 0.6469 | 0.6469 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1611 | 0.249 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0388 | 0.6469 | 0.6469 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0388 | 0.6469 | 1 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0162 | 0.2532 | 0.3914 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | nuclear receptor NHR-88 | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Onchocerca volvulus | 0.0023 | 0.0094 | 0.0108 | |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0023 | 0.0094 | 0.0094 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0019 | 0.0025 | 0.0038 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0019 | 0.0025 | 0.0025 |
Onchocerca volvulus | 0.0023 | 0.0094 | 0.0108 | |
Brugia malayi | ecdysteroid receptor | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0388 | 0.6469 | 0.6469 |
Echinococcus granulosus | polycomb protein suz12 A | 0.0328 | 0.542 | 0.542 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0205 | 0.3276 | 0.5064 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0388 | 0.6469 | 0.6469 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0023 | 0.0094 | 0.0094 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0023 | 0.0094 | 0.0094 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0051 | 0.0596 | 0.0922 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | ecdysone receptor | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0183 | 0.2893 | 0.4472 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.3276 | 0.5064 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.081 | 0.1252 |
Brugia malayi | nuclear receptor RXR | 0.0183 | 0.2893 | 0.4472 |
Schistosoma mansoni | nAChR subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Echinococcus granulosus | sodium channel protein | 0.0081 | 0.1113 | 0.1113 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0094 | 0.0146 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Schistosoma mansoni | nuclear hormone receptor | 0.0183 | 0.2893 | 0.2893 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0183 | 0.2893 | 0.2893 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0596 | 0.0596 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0183 | 0.2893 | 0.4472 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0019 | 0.0025 | 0.0038 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0205 | 0.3276 | 0.3276 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0023 | 0.0094 | 0.0094 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2893 | 0.4472 |
Loa Loa (eye worm) | SET domain-containing protein | 0.0283 | 0.4645 | 0.718 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0023 | 0.0094 | 0.0094 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0183 | 0.2893 | 0.2893 |
Loa Loa (eye worm) | serotonin transporter b | 0.0109 | 0.1611 | 0.249 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0388 | 0.6469 | 0.6469 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0388 | 0.6469 | 1 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0019 | 0.0025 | 0.0025 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0019 | 0.0025 | 0.0025 |
Brugia malayi | hypothetical protein | 0.0205 | 0.3276 | 0.5064 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0596 | 0.0922 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0023 | 0.0094 | 0.0094 |
Echinococcus multilocularis | Zinc finger protein jing protein | 0.059 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0388 | 0.6469 | 0.6469 |
Schistosoma mansoni | nuclear receptor | 0.0183 | 0.2893 | 0.2893 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0596 | 0.0596 |
Onchocerca volvulus | 0.0077 | 0.1052 | 0.1595 | |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0388 | 0.6469 | 0.6469 |
Echinococcus granulosus | histone lysine N methyltransferase Ez | 0.0283 | 0.4645 | 0.4645 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0038 | 0.0059 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0388 | 0.6469 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0038 | 1 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0019 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0051 | 0.0596 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0025 | 0.0038 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0023 | 0.0094 | 0.0094 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0023 | 0.0094 | 0.0146 |
Brugia malayi | nuclear receptor NHR-67 | 0.0183 | 0.2893 | 0.4472 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0023 | 0.0094 | 0.0094 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0183 | 0.2893 | 0.2893 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0388 | 0.6469 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.081 | 0.081 |
Schistosoma mansoni | zinc finger protein | 0.0183 | 0.2893 | 0.2893 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0183 | 0.2893 | 0.2893 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0023 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0388 | 0.6469 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0023 | 0.0094 | 0.0146 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0019 | 0.0025 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0388 | 0.6469 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0388 | 0.6469 | 0.6469 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 64.2 nM | Affinity against cocaine binding site of dopamine transporter in rat striatum using [3H]-2b as radioligand. | ChEMBL. | 1895292 |
IC50 (binding) | = 0.064 uM | Potency of the compound for the inhibition of [3H]-WIN-35,428 binding to the dopamine transporter | ChEMBL. | 1552510 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.