Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.002 | 0.0148 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0018 | 0.0088 | 0.0173 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.1042 | 0.0924 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.1042 | 0.2547 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.1042 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 1 |
Plasmodium vivax | vivapain-2 | 0.0018 | 0.0088 | 0.0141 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 0.5 |
Onchocerca volvulus | Terribly reduced optic lobes homolog | 0.002 | 0.0148 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.002 | 0.0148 | 0.0362 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.4091 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.1042 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0053 | 0.013 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 0.8506 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0053 | 0.013 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.002 | 0.0148 | 0.015 |
Onchocerca volvulus | 0.0042 | 0.1042 | 0.2383 | |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0088 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1042 | 0.2547 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.0078 | 0.0122 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.1042 | 0.2547 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Leishmania major | cathepsin L-like protease | 0.0018 | 0.0088 | 0.0173 |
Brugia malayi | beta-lactamase | 0.0042 | 0.1042 | 0.2547 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0469 | 0.1672 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0018 | 0.0088 | 0.012 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.013 | 0.0378 |
Brugia malayi | basement membrane proteoglycan precursor | 0.002 | 0.0148 | 0.0362 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0321 | 0.0786 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.013 | 0.0378 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.2542 | 1 |
Onchocerca volvulus | 0.002 | 0.0148 | 0.015 | |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.1042 | 0.2547 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0066 | 0.1987 | 0.661 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0078 | 0.0122 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0064 | 0.1905 | 0.633 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0042 | 0.102 | 0.3303 |
Brugia malayi | Low-density lipoprotein receptor-related protein, putative | 0.002 | 0.0148 | 0.0362 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0018 | 0.0088 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0538 | 0.1314 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.1042 | 0.0924 |
Loa Loa (eye worm) | cysteine protease | 0.0018 | 0.0088 | 0.0216 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.1586 | 0.5238 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0019 | 0.014 | 0.0298 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.1987 | 0.661 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.1586 | 0.3876 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0018 | 0.0088 | 0.012 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.1042 | 0.488 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.1042 | 0.0924 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.1042 | 0.0924 |
Schistosoma mansoni | bromodomain containing protein | 0.0073 | 0.2268 | 0.7569 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Echinococcus granulosus | low density lipoprotein receptor protein | 0.002 | 0.0148 | 0.0325 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.002 | 0.0148 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1042 | 0.2547 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.1586 | 0.5238 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0088 | 0.0216 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.1042 | 0.3781 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0538 | 0.1314 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0066 | 0.1992 | 0.4871 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0409 | 0.1215 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.4091 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.0469 | 0.1672 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.1042 | 0.488 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0053 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Leishmania major | cathepsin L-like protease | 0.0018 | 0.0088 | 0.0173 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0538 | 0.1656 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0321 | 0.0917 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0409 | 0.1215 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0018 | 0.0088 | 0.0216 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2979 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0018 | 0.0088 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Onchocerca volvulus | 0.002 | 0.0148 | 0.015 | |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.1042 | 0.3973 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.2979 | 0.7282 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Brugia malayi | jmjC domain containing protein | 0.0064 | 0.1905 | 0.4657 |
Echinococcus multilocularis | low density lipoprotein receptor protein | 0.002 | 0.0148 | 0.0325 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.2542 | 0.8506 |
Schistosoma mansoni | lamin | 0.0029 | 0.0538 | 0.1656 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.1586 | 0.6035 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0538 | 0.1314 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2979 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.013 | 0.0308 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0776 | 1 |
Onchocerca volvulus | 0.0029 | 0.0538 | 0.1123 | |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.1042 | 0.0924 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.1128 | 0.2757 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.1042 | 0.3379 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0053 | 0.013 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0018 | 0.0088 | 0.0141 |
Leishmania major | cathepsin L-like protease | 0.0018 | 0.0088 | 0.0173 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0538 | 0.1656 |
Brugia malayi | enteropeptidase precursor | 0.002 | 0.0148 | 0.0362 |
Brugia malayi | jmjC domain containing protein | 0.0066 | 0.1992 | 0.4871 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0053 | 0.013 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0028 | 0.0469 | 0.1672 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0409 | 0.1215 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0776 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.1586 | 0.6035 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0776 | 0.1896 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0053 | 0.1453 | 0.134 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0.1042 | 0.3781 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.002 | 0.0148 | 0.0362 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.1042 | 0.0924 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.208 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0018 | 0.0088 | 0.0141 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.1042 | 0.2547 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.002 | 0.0148 | 0.0325 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.4091 | 1 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.002 | 0.0148 | 0.0325 |
Echinococcus granulosus | cathepsin l1 | 0.0018 | 0.0088 | 0.012 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.1437 | 0.3513 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.002 | 0.0148 | 0.0325 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0053 | 0.1453 | 0.4783 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.013 | 0.0262 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.013 | 0.0317 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.1042 | 0.3379 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0066 | 0.1987 | 0.777 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0069 | 0.2105 | 0.7011 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0019 | 0.014 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0053 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2542 | 0.6214 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.1042 | 0.2547 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0078 | 0.0122 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0053 | 0.013 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.208 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.208 | 1 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.002 | 0.0148 | 0.0325 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.1042 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.013 | 0.0378 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.002 | 0.0148 | 0.0325 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0538 | 0.1314 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.013 | 0.0435 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.1987 | 0.77 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2979 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0063 | 0.1845 | 0.8844 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0054 | 0.1502 | 0.7148 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.0186 | 0.0455 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0538 | 0.1656 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0158 | 0.0386 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0776 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0018 | 0.0088 | 0.0216 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0538 | 0.1656 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.013 | 0.0262 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0066 | 0.1992 | 0.6628 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2979 | 1 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.2542 | 0.6214 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.002 | 0.0148 | 0.0325 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0538 | 0.1656 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.013 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1239 | 0.3029 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0776 | 0.247 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0273 | 0.0752 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.1042 | 0.0924 |
Brugia malayi | Bromodomain containing protein | 0.0087 | 0.2803 | 0.6851 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.1042 | 0.488 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.013 | 0.0262 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0018 | 0.0088 | 0.012 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0088 | 0.0216 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.002 | 0.0158 | 0.0358 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.208 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0273 | 0.0752 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0538 | 0.1314 |
Onchocerca volvulus | 0.0042 | 0.1042 | 0.2383 | |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0078 | 0.0085 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0158 | 0.0358 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.002 | 0.0148 | 0.0325 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.1042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1042 | 0.2547 |
Toxoplasma gondii | cathepsin CPL | 0.0018 | 0.0088 | 0.0141 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0053 | 0.1453 | 0.4783 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0064 | 0.1905 | 0.633 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0018 | 0.0088 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0148 | 0.0325 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.1042 | 0.0924 |
Leishmania major | cysteine peptidase A (CPA) | 0.0018 | 0.0088 | 0.0173 |
Mycobacterium leprae | Probable lipase LipE | 0.0042 | 0.1042 | 0.2763 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0042 | 0.102 | 0.3303 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.002 | 0.0148 | 0.0325 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0066 | 0.1987 | 0.1882 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0018 | 0.0088 | 0.0141 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0158 | 0.0358 |
Onchocerca volvulus | 0.002 | 0.0148 | 0.015 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0776 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.1042 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.013 | 0.0262 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.1987 | 0.661 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.1042 | 0.0924 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0776 | 0.247 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2979 | 1 |
Onchocerca volvulus | 0.0029 | 0.0538 | 0.1123 | |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.208 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.4091 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Loa Loa (eye worm) | fibroinase | 0.0018 | 0.0088 | 0.0216 |
Loa Loa (eye worm) | calcium binding EGF domain-containing protein | 0.002 | 0.0148 | 0.0362 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0066 | 0.1992 | 0.6628 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.1042 | 0.3379 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.002 | 0.0148 | 0.0362 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0018 | 0.0088 | 0.012 |
Echinococcus granulosus | lamin | 0.0029 | 0.0538 | 0.1656 |
Schistosoma mansoni | jumonji domain containing protein | 0.0064 | 0.1905 | 0.633 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0069 | 0.208 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0088 | 0.0216 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0517 | 0.1263 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0088 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.2608 | 0.6374 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0776 | 0.247 |
Loa Loa (eye worm) | ctsf protein | 0.0018 | 0.0088 | 0.0216 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0053 | 0.1453 | 0.134 |
Brugia malayi | CUB domain containing protein | 0.002 | 0.0148 | 0.0362 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.1987 | 0.77 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.2542 | 1 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.002 | 0.0148 | 0.0325 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0053 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0148 | 0.0325 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.1042 | 0.0924 |
Onchocerca volvulus | Arrow homolog | 0.002 | 0.0148 | 0.015 |
Onchocerca volvulus | 0.002 | 0.0148 | 0.015 | |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 1 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Schistosoma mansoni | lamin | 0.0029 | 0.0538 | 0.1656 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.013 | 0.0308 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.013 | 0.0378 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.1042 | 0.3379 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.002 | 0.0148 | 0.0325 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0088 | 0.0216 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0053 | 0.1453 | 0.4744 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1042 | 0.2547 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0.1042 | 0.3781 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.002 | 0.0148 | 0.0325 |
Mycobacterium leprae | conserved hypothetical protein | 0.0042 | 0.1042 | 0.2763 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.002 | 0.0158 | 0.0358 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0.1042 | 0.3781 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0053 | 0.013 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0469 | 0.1407 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0066 | 0.1987 | 0.661 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.1042 | 0.488 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.1586 | 0.7563 |
Trypanosoma brucei | ISWI complex protein | 0.0018 | 0.0078 | 0.0122 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.013 | 0.0603 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.013 | 0.0435 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2979 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.1586 | 0.5238 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0.1042 | 0.3781 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.208 | 1 |
Echinococcus granulosus | Low density lipoprotein receptor class A cysteine rich | 0.002 | 0.0148 | 0.0325 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0066 | 0.1987 | 0.9544 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0158 | 0.0358 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0078 | 0.0085 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0273 | 0.0752 |
Leishmania major | cathepsin L-like protease | 0.0018 | 0.0088 | 0.0173 |
Onchocerca volvulus | 0.002 | 0.0148 | 0.015 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0018 | 0.0088 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1042 | 0.2547 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.2979 | 0.7282 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1131 | 0.2765 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0517 | 0.1263 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0776 | 0.247 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0018 | 0.0088 | 0.012 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0148 | 0.0325 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.013 | 0.0317 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.013 | 0.0308 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0538 | 0.1656 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.002 | 0.0158 | 0.0358 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0018 | 0.0088 | 0.012 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0158 | 0.0358 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.2542 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0069 | 0.2105 | 0.7011 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0053 | 0.013 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0064 | 0.1905 | 0.633 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0088 | 0.0216 |
Echinococcus multilocularis | cysteine protease | 0.0018 | 0.0088 | 0.012 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.1042 | 1 |
Leishmania major | cathepsin L-like protease | 0.0018 | 0.0088 | 0.0173 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.2542 | 0.8506 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1042 | 0.2547 |
Onchocerca volvulus | 0.0042 | 0.1042 | 0.2383 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2979 | 1 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.002 | 0.0148 | 0.0362 |
Brugia malayi | hypothetical protein | 0.012 | 0.4091 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.1987 | 0.77 |
Echinococcus granulosus | 5'partial|Low density lipoprotein receptor class A cysteine rich | 0.002 | 0.0148 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0148 | 0.0362 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1326 | 0.3242 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.002 | 0.0148 | 0.0325 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.2542 | 1 |
Plasmodium vivax | vivapain-2 | 0.0018 | 0.0088 | 0.0141 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.1586 | 0.1475 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0066 | 0.1992 | 0.6628 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.208 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.002 | 0.0158 | 0.0358 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.1042 | 0.3973 |
Onchocerca volvulus | 0.002 | 0.0148 | 0.015 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 28.1838 uM | PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.