Detailed information for compound 1540586

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 510.38 | Formula: C25H24BrN3O4
  • H donors: 0 H acceptors: 4 LogP: 3.07 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 2
  • SMILES: Brc1ccc(cc1)[C@@H]1[C@@H]2C(=O)N(C(=O)[C@@H]2[C@]2(N1C(=O)N(C2=O)c1ccccc1)C)C(C)(C)C
  • InChi: 1S/C25H24BrN3O4/c1-24(2,3)29-20(30)17-18(21(29)31)25(4)22(32)27(16-8-6-5-7-9-16)23(33)28(25)19(17)14-10-12-15(26)13-11-14/h5-13,17-19H,1-4H3/t17-,18-,19-,25-/m1/s1
  • InChiKey: WQMFTPFXXFAPID-LLBQEJIASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0009 0.0016
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0003 0.004
Brugia malayi follicle stimulating hormone receptor 0.0237 0.09 0.1742
Echinococcus multilocularis smad 0.0033 0.007 0.007
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0145 0.0261
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0038 0.009 0.0161
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0122
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0042 0.0109 0.0259
Loa Loa (eye worm) MH2 domain-containing protein 0.0482 0.1892 0.4134
Brugia malayi cytoplasmic intermediate filament protein 0.0057 0.017 0.0329
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0069 0.0216 0.2961
Loa Loa (eye worm) hypothetical protein 0.005 0.0139 0.0303
Loa Loa (eye worm) hypothetical protein 0.0104 0.036 0.0788
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0031 0.0058
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0042 0.0109 0.149
Leishmania major d-xylulose reductase, putative 0.0042 0.0109 0.1414
Brugia malayi Methyltransferase-like protein 4 0.0205 0.0768 0.1487
Schistosoma mansoni cpg binding protein 0.0063 0.0193 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0038 0.009 0.0173
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0009 0.0016
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0006 0.0013
Echinococcus multilocularis musashi 0.0107 0.0372 0.0372
Brugia malayi AMP-binding enzyme family protein 0.021 0.0789 0.1528
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0488 0.0877
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.045 0.1762 0.4328
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.068 0.2696 0.6637
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0031 0.0069
Leishmania major cathepsin L-like protease 0.0051 0.0145 0.1889
Loa Loa (eye worm) acyl carrier protein 0.0069 0.0216 0.0472
Leishmania major hypothetical protein, conserved 0.0205 0.0768 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0009 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0062 0.0111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.0068
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0214 0.0804 0.1973
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.007 0.022 0.0524
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0014 0.0014
Brugia malayi Pre-SET motif family protein 0.0206 0.0774 0.1497
Brugia malayi CXXC zinc finger family protein 0.006 0.0179 0.0346
Brugia malayi nuclear receptor NHR-88 0.0038 0.009 0.0173
Loa Loa (eye worm) latrophilin receptor protein 2 0.0093 0.0315 0.0688
Brugia malayi ecdysone receptor 0.0018 0.0009 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0031 0.0058
Loa Loa (eye worm) hypothetical protein 0.0105 0.0364 0.0794
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0133 0.1819
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0133 0.1819
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0173 0.0173
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0007 0.0116
Brugia malayi Cathepsin L-like precursor 0.0051 0.0145 0.0281
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0171 0.063 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0038 0.009 0.0161
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0038 0.009 0.0175
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0145 0.0278
Onchocerca volvulus 0.0054 0.0156 0.03
Schistosoma mansoni DNA polymerase eta 0.0023 0.0032 0.0057
Schistosoma mansoni coup transcription factor 0.0038 0.009 0.0161
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.007 0.022 0.0524
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0113 0.0393
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0042 0.0109 0.021
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0062 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Brugia malayi MH1 domain containing protein 0.0033 0.007 0.0136
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0032 0.059
Mycobacterium ulcerans polyketide synthase 0.0722 0.2868 0.7056
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0009 0.0009
Onchocerca volvulus 0.0031 0.0062 0.0107
Echinococcus multilocularis cysteine protease 0.0051 0.0145 0.0145
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0042 0.0109 0.2572
Brugia malayi intermediate filament protein 0.0107 0.0372 0.0719
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0659 0.2612 0.6428
Leishmania major cathepsin L-like protease 0.0195 0.0729 0.9492
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0031 0.057
Echinococcus multilocularis AMP dependent ligase 0.007 0.022 0.022
Brugia malayi conserved hypotetical protein 0.0018 0.0009 0.0018
Loa Loa (eye worm) nuclear hormone receptor 0.0105 0.0364 0.0796
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0038 0.009 0.0196
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0009 0.002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.0488 0.0943
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0038 0.009 0.0196
Plasmodium vivax unspecified product 0.0017 0.0006 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Brugia malayi cathepsin L-like precursor 0.0034 0.0076 0.0148
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0214 0.0804 0.1974
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0015 0.0141
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0042 0.0109 0.149
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0294 0.1131 0.2471
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0197
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0113 0.0397 0.0713
Brugia malayi Intermediate filament tail domain containing protein 0.0107 0.0372 0.0719
Echinococcus granulosus dna polymerase kappa 0.0023 0.0032 0.0057
Plasmodium vivax vivapain-2 0.0051 0.0145 0.2305
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0038 0.009 0.0161
Brugia malayi isocitrate dehydrogenase 0.0048 0.0133 0.0257
Loa Loa (eye worm) hypothetical protein 0.1144 0.4576 1
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0076 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.009 0.0173
Leishmania major DNA polymerase kappa, putative 0.0023 0.0032 0.0414
Treponema pallidum acyl carrier protein 0.0069 0.0216 1
Toxoplasma gondii acyl carrier protein ACP 0.0069 0.0216 0.0752
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0125 0.0445 0.08
Schistosoma mansoni hypothetical protein 0.0142 0.0513 0.0923
Onchocerca volvulus 0.0642 0.2543 0.5169
Brugia malayi Cathepsin L-like precursor 0.0034 0.0076 0.0148
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0373 0.0373
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0171 0.063 0.1133
Schistosoma mansoni rotamase 0.0034 0.0076 0.0137
Echinococcus multilocularis expressed protein 0.0034 0.0076 0.0076
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0042 0.0109 0.0237
Schistosoma mansoni hypothetical protein 0.0853 0.3396 0.6107
Brugia malayi latrophilin 2 splice variant baaae 0.0201 0.0753 0.1458
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0145 0.0261
Mycobacterium ulcerans quinone oxidoreductase 0.0042 0.0109 0.025
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0069 0.0216 0.2961
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0113 0.124
Giardia lamblia Methyltransferase like 2 0.0205 0.0768 1
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0007 0.0116
Loa Loa (eye worm) nuclear factor I 0.0018 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Echinococcus granulosus lamin 0.0107 0.0372 0.0668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0015 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0076 0.083
Schistosoma mansoni cpg binding protein 0.0063 0.0193 0.0347
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0043 0.0111 0.1769
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0042 0.0109 0.025
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Echinococcus multilocularis survival motor neuron protein 1 0.0696 0.2762 0.2762
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0076 0.0166
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0729 1
Brugia malayi N-terminal motif family protein 0.0182 0.0674 0.1305
Echinococcus multilocularis cysteine protease 0.0051 0.0145 0.0145
Schistosoma mansoni ap endonuclease 0.0019 0.0015 0.0028
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0009 0.0122
Schistosoma mansoni hypothetical protein 0.0093 0.0315 0.0566
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0009 0.0009
Echinococcus granulosus cathepsin l1 0.0034 0.0076 0.0137
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0032 0.0062
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0044 0.008
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0075 0.0243 0.0591
Echinococcus multilocularis mucolipin 3 0.0064 0.0198 0.0198
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0166 0.0611 0.1498
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0069 0.0216 0.0524
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0397 0.5439
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0032 0.0062
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0179 0.0391
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0122
Brugia malayi jmjC domain containing protein 0.0058 0.0173 0.0334
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0032 0.006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0075 0.0243 0.0583
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.009 0.0161
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0145 0.0317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Echinococcus multilocularis microtubule associated protein 2 0.1386 0.5561 0.5561
Entamoeba histolytica hypothetical protein 0.0107 0.0373 0.9387
Brugia malayi hypothetical protein 0.0054 0.0156 0.0302
Entamoeba histolytica acyl-CoA synthetase, putative 0.0092 0.031 0.7756
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.009 0.0173
Brugia malayi Cathepsin L-like precursor 0.0051 0.0145 0.0281
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.022 0.0534
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0722 0.2868 0.7056
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0042 0.0109 0.025
Mycobacterium ulcerans dehydrogenase 0.0042 0.0109 0.025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0113 0.0397 0.0397
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0069 0.0216 0.0422
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0104 0.036 0.088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0397 0.5439
Mycobacterium ulcerans quinone oxidoreductase 0.0042 0.0109 0.025
Mycobacterium ulcerans Type I modular polyketide synthase 0.068 0.2696 0.6634
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0032 0.007
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0073 0.0998
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0038 0.009 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0016
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0003 0.004
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0043 0.0111 0.173
Onchocerca volvulus 0.0038 0.009 0.0164
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0729 1
Loa Loa (eye worm) hypothetical protein 0.0294 0.1131 0.2471
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Onchocerca volvulus 0.0051 0.0145 0.0278
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0171 0.063 0.8196
Brugia malayi MH2 domain containing protein 0.0033 0.007 0.0136
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0038 0.009 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0133 0.0462
Toxoplasma gondii type I fatty acid synthase 0.0104 0.036 0.1255
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Mycobacterium ulcerans fatty acid synthase Fas 0.0214 0.0804 0.1965
Mycobacterium leprae conserved hypothetical protein 0.0069 0.0216 0.0525
Brugia malayi MH2 domain containing protein 0.0482 0.1892 0.3661
Trichomonas vaginalis set domain proteins, putative 0.0234 0.0888 1
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0171 0.063 0.8635
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0015 0.0028
Brugia malayi Cathepsin L-like precursor 0.0051 0.0145 0.0281
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0006 0.0012
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0042 0.0109 0.0259
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0113 0.0397 1
Schistosoma mansoni hypothetical protein 0.0069 0.0216 0.0388
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0113 0.0397 0.0713
Echinococcus granulosus microtubule associated protein 2 0.1386 0.5561 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0054 0.0157 0.0157
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0042 0.0109 0.025
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0397 0.5439
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0042 0.0109 0.025
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0009 0.0009
Echinococcus multilocularis dna polymerase eta 0.0023 0.0032 0.0032
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0042 0.0109 0.0259
Mycobacterium tuberculosis Conserved protein 0.0205 0.0768 0.1885
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.009 0.0173
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0043 0.0111 0.1562
Mycobacterium ulcerans polyketide synthase Pks13 0.1017 0.4061 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0032 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0062 0.0111
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0009 0.0017
Brugia malayi hypothetical protein 0.002 0.0018 0.0034
Brugia malayi Calcitonin receptor-like protein seb-1 0.0294 0.1131 0.2188
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0044 0.0086
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0125 0.0445 0.0445
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0042 0.0109 0.2572
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0488 0.0877
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0722 0.2868 0.706
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0042 0.0109 0.021
Mycobacterium ulcerans thioesterase TesA 0.0567 0.2236 0.5499
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Echinococcus multilocularis lamin dm0 0.0107 0.0372 0.0372
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0032 0.0057
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0294 0.1131 0.2188
Onchocerca volvulus 0.1191 0.4767 0.9707
Schistosoma mansoni hypothetical protein 0.0107 0.0373 0.0671
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0044 0.0608
Echinococcus granulosus geminin 0.0853 0.3396 0.6107
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0044 0.0914
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0031 0.0403
Onchocerca volvulus 0.0034 0.0076 0.0137
Schistosoma mansoni hypothetical protein 0.0201 0.0753 0.1354
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0036 0.0036
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0076 0.0137
Leishmania major hypothetical protein, conserved 0.0043 0.0111 0.145
Brugia malayi Steroid receptor seven-up type 2 0.0125 0.0445 0.0861
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0104 0.036 0.088
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0009 0.0016
Brugia malayi nuclear receptor NHR-88 0.0018 0.0009 0.0018
Onchocerca volvulus Protein cycle homolog 0.0038 0.0091 0.0168
Leishmania major cathepsin L-like protease 0.0195 0.0729 0.9492
Schistosoma mansoni nuclear hormone receptor 0.0038 0.009 0.0161
Loa Loa (eye worm) intermediate filament protein 0.0107 0.0372 0.0812
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0038 0.009 0.0173
Mycobacterium ulcerans polyketide synthase MbtC 0.0171 0.063 0.1536
Entamoeba histolytica hypothetical protein 0.0024 0.0036 0.069
Mycobacterium ulcerans polyketide synthase MbtD 0.0209 0.0786 0.192
Echinococcus multilocularis NADH dehydrogenase 0.0069 0.0216 0.0216
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0133 0.1819
Trichomonas vaginalis rotamase, putative 0.0033 0.0073 0.0789
Schistosoma mansoni nuclear receptor 0.0018 0.0009 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0044 0.0914
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0032 0.007
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0043 0.0111 0.0216
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.09 0.1967
Trypanosoma brucei oxidoreductase, putative 0.0042 0.0109 0.149
Echinococcus granulosus acyl carrier protein mitochondrial 0.0069 0.0216 0.0388
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0171 0.063 0.8635
Leishmania major oxidoreductase, putative 0.0042 0.0109 0.1414
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0397 0.4448
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0567 0.2236 0.5504
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.007 0.0127
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.0068
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0145 0.2305
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0009 0.0116
Onchocerca volvulus 0.0051 0.0145 0.0278
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0441 0.1727 0.6015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0038 0.009 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.002 0.0018 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.009 0.0173
Mycobacterium leprae Polyketide synthase Pks13 0.1017 0.4061 1
Schistosoma mansoni cathepsin s 0.0017 0.0006 0.0011
Leishmania major DNA polymerase eta, putative 0.0023 0.0032 0.0414
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0145 0.0281
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0043 0.0111 0.1769
Echinococcus multilocularis lamin 0.0107 0.0372 0.0372
Trichomonas vaginalis rotamase, putative 0.0034 0.0076 0.0826
Entamoeba histolytica hypothetical protein 0.0107 0.0373 0.9387
Plasmodium vivax acyl carrier protein, putative 0.0069 0.0216 0.3429
Plasmodium vivax vivapain-1 0.0026 0.0044 0.0704
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0015 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Schistosoma mansoni mucolipin 0.0064 0.0198 0.0356
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0043 0.0111 0.02
Schistosoma mansoni smad1 5 8 and 0.0033 0.007 0.0127
Plasmodium vivax unspecified product 0.0026 0.0044 0.0704
Leishmania major oxidoreductase-like protein 0.0042 0.0109 0.1414
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0036 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0038 0.009 0.009
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0044 0.0608
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0015 0.0029
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0032 0.0032
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0038 0.0091 0.02
Echinococcus granulosus dna polymerase eta 0.0023 0.0032 0.0057
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.002 0.0018 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0182 0.0432
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0197
Brugia malayi MH2 domain containing protein 0.0033 0.007 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0145 0.1606
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0042 0.0109 0.0259
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0044 0.0914
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.0068
Echinococcus multilocularis GPCR, family 2 0.0093 0.0315 0.0315
Brugia malayi Cathepsin L-like precursor 0.0051 0.0145 0.0281
Giardia lamblia DINP protein human, muc B family 0.0023 0.0032 0.0301
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0032 0.0436
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0373 0.0671
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0032 0.0326
Toxoplasma gondii quinone oxidoreductase, putative 0.0042 0.0109 0.0378
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0006 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0182 0.0674 0.1473
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0722 0.2868 0.7059
Brugia malayi Pre-SET motif family protein 0.0031 0.0062 0.0119
Mycobacterium ulcerans short-chain dehydrogenase 0.005 0.014 0.0328
Echinococcus multilocularis cpg binding protein 0.0063 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0016
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0345 0.1336 0.4651
Echinococcus multilocularis cathepsin L 0.0026 0.0044 0.0044
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0133 0.029
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0133 0.2107
Trypanosoma cruzi oxidoreductase, putative 0.0042 0.0109 0.149
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0038 0.009 0.0173
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0042 0.0109 0.149
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0042 0.0109 0.025
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0145 0.0278
Loa Loa (eye worm) hypothetical protein 0.0042 0.0109 0.0237
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0107 0.0373 0.0815
Schistosoma mansoni methyltransferase-related 0.0205 0.0768 0.1382
Schistosoma mansoni microtubule-associated protein tau 0.1386 0.5561 1
Echinococcus granulosus Smad4 0.0033 0.007 0.0127
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0039
Leishmania major cathepsin L-like protease 0.0051 0.0145 0.1889
Mycobacterium ulcerans polyketide synthase Pks9 0.045 0.1762 0.4328
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0642 0.2543 0.6258
Onchocerca volvulus 0.0234 0.0888 0.1794
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0073 0.0254
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0145 0.0278
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0145 0.2305
Schistosoma mansoni hypothetical protein 0.0849 0.338 0.6078
Brugia malayi nuclear receptor RXR 0.002 0.0018 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0113 0.0397 0.0713
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.068 0.2696 0.6637
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0009 0.0122
Schistosoma mansoni thyroid hormone receptor 0.0038 0.009 0.0161
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0009 0.0016
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0093 0.0315 0.0609
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0032 0.0436
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0042 0.0109 0.025
Mycobacterium tuberculosis Possible dehydrogenase 0.0042 0.0109 0.0259
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0038 0.009 0.0161
Schistosoma mansoni mucolipin 0.0059 0.0176 0.0317
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0031 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0031 0.0403
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0052 0.0147 0.0264
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0009 0.0031
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0009 0.0122
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0182 0.0674 0.1357
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0044 0.008
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0197
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.068 0.2696 0.6634
Trypanosoma brucei oxidoreductase, putative 0.0042 0.0109 0.149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Onchocerca volvulus 0.0051 0.0145 0.0278
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0182 0.0182
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0042 0.0109 0.026
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.0774 0.169
Loa Loa (eye worm) acyl carrier protein 0.0313 0.1206 0.2635
Schistosoma mansoni zinc binding dehydrogenase 0.0042 0.0109 0.0195
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0145 0.0145
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0021
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0042 0.0109 0.025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0186 0.0335
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0007 0.0069
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0142 0.0513 0.0994
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0032 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0373 0.0671
Leishmania major nuclear receptor binding factor-like protein 0.0042 0.0109 0.1414
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0024
Schistosoma mansoni thyroid hormone receptor 0.0038 0.009 0.0161
Loa Loa (eye worm) transcription factor SMAD2 0.0482 0.1892 0.4134
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.007 0.0127
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0015 0.0015
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0038 0.0091 0.0164
Schistosoma mansoni intermediate filament proteins 0.0107 0.0372 0.0668
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0009 0.0116
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0042 0.0109 0.1194
Onchocerca volvulus 0.0051 0.0145 0.0278
Onchocerca volvulus 0.0083 0.0275 0.0542
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0113 0.0203
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0003 0.0038
Entamoeba histolytica hypothetical protein 0.0107 0.0373 0.9387
Schistosoma mansoni hypothetical protein 0.0853 0.3396 0.6107
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0098 0.2301
Echinococcus granulosus dnaJ subfamily B 0.0849 0.338 0.6078
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0517 0.093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0076 0.083
Trypanosoma cruzi acyl transferase-like protein 0.0043 0.0111 0.1528
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0016
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0044 0.0608
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0016 0.0004 0.0004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0414 0.1442
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0044 0.008
Schistosoma mansoni aryl hydrocarbon receptor 0.0016 0.0004 0.0007
Echinococcus multilocularis dnaJ subfamily B 0.0849 0.338 0.338
Brugia malayi nuclear receptor RXR 0.0018 0.0009 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0076 0.1741
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.068 0.2696 0.5219
Echinococcus multilocularis thyroid hormone receptor alpha 0.0038 0.009 0.009
Toxoplasma gondii cathepsin CPL 0.0051 0.0145 0.0506
Schistosoma mansoni nuclear receptor 0.0018 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0381 0.1483 0.3241
Schistosoma mansoni retinoic acid receptor RXR 0.0038 0.009 0.0161
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0009 0.0122
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0075 0.0243 0.0593
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0488 0.0488
Echinococcus granulosus FTZ F1 alpha 0.0038 0.009 0.0161
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0133 0.0133
Schistosoma mansoni single-minded 0.0016 0.0003 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Schistosoma mansoni smad1 5 8 and 0.0033 0.007 0.0127
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.002 0.0018 0.0039
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0042 0.0109 0.149
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0073 0.0948
Loa Loa (eye worm) hypothetical protein 0.0021 0.0022 0.0048
Echinococcus granulosus aryl hydrocarbon receptor 0.0054 0.0157 0.0282
Schistosoma mansoni hypothetical protein 0.0093 0.0315 0.0566
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0009 0.0009
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0076 0.0147
Schistosoma mansoni ap endonuclease 0.0019 0.0015 0.0028
Loa Loa (eye worm) cysteine protease 0.0051 0.0145 0.0317
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0209 0.0786 0.1928
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0076 0.0148
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0075 0.0243 0.0583
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0036 0.0489
Onchocerca volvulus 0.006 0.0179 0.0347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0036 0.037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Loa Loa (eye worm) steroid hormone receptor 0.0038 0.009 0.0196
Brugia malayi tailless protein 0.0018 0.0009 0.0018
Echinococcus granulosus NADH dehydrogenase 0.0069 0.0216 0.0388
Echinococcus granulosus cathepsin L 0.0026 0.0044 0.008
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.022 0.5437
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0042 0.0109 0.0378
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0145 0.0145
Brugia malayi ecdysteroid receptor 0.0038 0.009 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0044 0.0704
Echinococcus granulosus smad 0.0033 0.007 0.0127
Mycobacterium tuberculosis Possible dehydrogenase 0.0042 0.0109 0.0259
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0534 0.1034
Loa Loa (eye worm) hypothetical protein 0.0113 0.0397 0.0867
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0113 0.0397 0.5163
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0043 0.0111 0.0111
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0042 0.0109 0.025
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.022 0.0533
Brugia malayi hypothetical protein 0.002 0.0018 0.0034
Brugia malayi hypothetical protein 0.0119 0.0422 0.0816
Schistosoma mansoni Smad4 0.0033 0.007 0.0127
Onchocerca volvulus 0.0042 0.0109 0.0203
Entamoeba histolytica cysteine protease, putative 0.0051 0.0145 0.3514
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.007 0.007
Mycobacterium ulcerans Type I modular polyketide synthase 0.068 0.2696 0.6634
Leishmania major cathepsin L-like protease 0.0051 0.0145 0.1889
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.068 0.2696 0.6637
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0075 0.0243 0.0591
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0534 0.096
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0042 0.0109 0.1194
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0075 0.0243 0.0583
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0015 0.0212
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0133 0.1819
Mycobacterium leprae Probable oxidireductase 0.0042 0.0109 0.026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0073 0.0998
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0151 0.033
Brugia malayi hypothetical protein 0.0018 0.0009 0.0018
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0133 0.0239
Brugia malayi Cathepsin L-like precursor 0.0017 0.0006 0.0012
Echinococcus granulosus ecdysone induced protein 78C 0.0038 0.009 0.0161
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0042 0.0109 0.026
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0145 0.3514
Trypanosoma cruzi oxidoreductase, putative 0.0042 0.0109 0.149
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.1289 0.5167 1
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.009 0.0173
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.0009 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0642 0.2543 0.4921
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0044 0.0914
Mycobacterium ulcerans oxidoreductase 0.0042 0.0109 0.025
Mycobacterium ulcerans acyl carrier protein 0.0069 0.0216 0.0515
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0044 0.0914
Loa Loa (eye worm) hypothetical protein 0.0696 0.2762 0.6036
Loa Loa (eye worm) ctsf protein 0.0051 0.0145 0.0317
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0036 0.0489
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0042 0.0109 0.1517
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0034 0.0076 0.0167
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.007 0.0154
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0062 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0069 0.0216 0.3264
Loa Loa (eye worm) hypothetical protein 0.0119 0.0422 0.0921
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0042 0.0109 0.0259
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0042 0.0109 0.021
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0009 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0038 0.009 0.0161
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0002 0.0003
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0145 0.0261
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0038 0.0091 0.0177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0044 0.0468
Mycobacterium ulcerans thioesterase 0.0567 0.2236 0.5499
Mycobacterium ulcerans quinone reductase Qor 0.0042 0.0109 0.025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0075 0.0243 0.0471
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0036 0.0124
Echinococcus granulosus cysteine protease 0.0026 0.0044 0.008
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.1017 0.4061 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0044 0.0914
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0009 0.0016
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0133 0.0462
Toxoplasma gondii type I fatty acid synthase, putative 0.0484 0.1901 0.6621
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0122
Brugia malayi Cathepsin L-like precursor 0.0051 0.0145 0.0281
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0042 0.0109 0.149
Loa Loa (eye worm) hypothetical protein 0.0042 0.0109 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0722 0.2868 0.706
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0042 0.0109 0.026
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0042 0.0109 0.025
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0556 0.2194 0.5398
Schistosoma mansoni steroid hormone receptor ad4bp 0.0038 0.009 0.0161
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0042 0.0109 0.2572
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0052 0.0147 0.0321
Brugia malayi nuclear receptor NHR-67 0.0018 0.0009 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.009 0.0173
Schistosoma mansoni smad 0.0033 0.007 0.0127
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0032 0.0326
Brugia malayi Smad1 0.0033 0.007 0.0136
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.009 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0113 0.0397 0.0397
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0018 0.0034
Schistosoma mansoni hypothetical protein 0.0093 0.0315 0.0566
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0145 0.0261
Schistosoma mansoni survival motor neuron protein 0.0142 0.0513 0.0923
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0009 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Leishmania major quinone oxidoreductase, putative 0.0042 0.0109 0.1414
Trypanosoma cruzi oxidoreductase, putative 0.0042 0.0109 0.149
Loa Loa (eye worm) hypothetical protein 0.0119 0.0422 0.0921
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0145 0.0317
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.0009 0.0016
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.0009 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.0038 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0107 0.0372 0.0812
Mycobacterium leprae Probable polyketide synthase Pks1 0.0722 0.2868 0.706
Echinococcus multilocularis Smad4 0.0033 0.007 0.007
Brugia malayi photoreceptor-specific nuclear receptor 0.0038 0.009 0.0173
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0007 0.0009
Onchocerca volvulus 0.0042 0.0109 0.0203
Trypanosoma cruzi acyl transferase-like protein, putative 0.0043 0.0111 0.1528
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0038 0.009 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0171 0.063 0.8635
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Mycobacterium ulcerans oxidoreductase FadB5 0.0042 0.0109 0.025
Plasmodium vivax vivapain-3 0.0026 0.0044 0.0704
Schistosoma mansoni RAR-like nuclear receptor 0.0038 0.009 0.0161
Trypanosoma brucei unspecified product 0.0023 0.0032 0.0436
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0069 0.0216 0.0524
Echinococcus granulosus lamin dm0 0.0107 0.0372 0.0668
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0044 0.0608
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.0009 0.0016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0015 0.0201
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0113 0.124
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0015 0.003
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0042 0.0109 0.1194
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0171 0.063 0.1536
Schistosoma mansoni [ACP] S-malonyltransferase 0.0043 0.0111 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Brugia malayi nuclear hormone receptor 0.0038 0.009 0.0173
Toxoplasma gondii type I fatty acid synthase, putative 0.0723 0.2872 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0052 0.0094
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0016
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0145 0.3514
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0031 0.0058
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.009 0.009
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0075 0.0243 0.0583
Echinococcus multilocularis ubiquitin specific protease 41 0.0113 0.0397 0.0397
Trypanosoma brucei unspecified product 0.0016 0.0002 0.0034
Schistosoma mansoni [ACP] S-malonyltransferase 0.0043 0.0111 0.02
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0009 0.0019
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0042 0.0109 0.0259
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0002 0.0003
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0182 0.0328
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0032 0.0436
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0186 0.0335
Leishmania major zinc-binding dehydrogenase-like protein 0.0042 0.0109 0.1414
Echinococcus granulosus ubiquitin specific protease 41 0.0113 0.0397 0.0713
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0031 0.0403
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0113 0.179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.002 0.0018 0.0018
Trypanosoma brucei acyl transferase-like protein 0.0043 0.0111 0.1528
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0075 0.0243 0.0591
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0036 0.0069
Loa Loa (eye worm) Smad1 0.0033 0.007 0.0154
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.045 0.1762 0.4334
Echinococcus granulosus mucolipin 3 0.0064 0.0198 0.0356
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0042 0.0109 0.0259
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0042 0.0109 0.0259
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0009 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0145 0.1606
Mycobacterium ulcerans acyl carrier protein 0.0069 0.0216 0.0515
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0234 0.0886 0.2174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0093 0.0315 0.0315
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.068 0.2696 0.6634
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0171 0.063 0.1376
Mycobacterium ulcerans polyketide synthase 0.068 0.2696 0.6634
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0178 0.0661 0.9058
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.007 0.0127
Echinococcus multilocularis ecdysone induced protein 78C 0.0038 0.009 0.009
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0171 0.063 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0032 0.0069
Echinococcus granulosus survival motor neuron protein 1 0.0696 0.2762 0.4967
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.0009 0.0018
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0186 0.0407
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0145 0.1606
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0016 0.0004 0.0007
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0069 0.0216 0.0216
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0113 0.0397 0.0768
Onchocerca volvulus Huntingtin homolog 0.0119 0.0422 0.0842
Brugia malayi hypothetical protein 0.0018 0.0009 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0113 0.0397 0.4448
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0171 0.063 0.2193
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0145 0.2305
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0113 0.0397 0.4448
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0044 0.0608
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0387 0.1506 0.3703
Toxoplasma gondii acyl transferase domain-containing protein 0.0043 0.0111 0.0388
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0113 0.0393
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0038 0.009 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0038 0.009 0.0173
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0722 0.2868 0.7059
Echinococcus granulosus intermediate filament protein 0.0107 0.0372 0.0668
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0044 0.0468
Loa Loa (eye worm) fibroinase 0.0051 0.0145 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0009 0.0018
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0104 0.036 0.088
Schistosoma mansoni lamin 0.0107 0.0372 0.0668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0031 0.006
Trypanosoma cruzi major cysteine proteinase, putative 0.0153 0.056 0.7676
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0104 0.036 0.0881
Loa Loa (eye worm) histone methyltransferase 0.002 0.0016 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0182 0.2373
Loa Loa (eye worm) hypothetical protein 0.0051 0.0145 0.0317
Brugia malayi steroid hormone receptor 0.0038 0.009 0.0173
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0182 0.0432
Mycobacterium ulcerans hypothetical protein 0.0069 0.0216 0.0515
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0133 0.0257
Schistosoma mansoni [ACP] S-malonyltransferase 0.0043 0.0111 0.02
Brugia malayi hypothetical protein 0.0038 0.0091 0.0177
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0009 0.002
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0173 0.031
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0032 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.0768 0.8646
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0009 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0031 0.0058
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0036 0.0064
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0069 0.0216 0.0524
Onchocerca volvulus 0.0142 0.0513 0.1029
Trypanosoma cruzi cruzipain precursor, putative 0.0195 0.0729 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0057 0.017 0.0371
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0031 0.0069
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0171 0.063 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0076 0.0167
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0145 0.1889
Mycobacterium ulcerans hypothetical protein 0.0023 0.0031 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.009 0.009
Brugia malayi nuclear hormone receptor 0.0018 0.0009 0.0018
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0038 0.009 0.0161
Onchocerca volvulus 0.0051 0.0145 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0009 0.0116
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0133 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0002 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0243 0.0583
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0062 0.0062
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0009 0.0118
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0009 0.0016
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0133 0.0133
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0133 0.0318
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0009 0.0018
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0009 0.0122
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0547 0.2157 0.5304
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0009 0.0009
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0042 0.0109 0.0109
Brugia malayi Alcohol dehydrogenase class III 0.0042 0.0109 0.021
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0032 0.0057
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0042 0.0109 0.0259
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0009 0.0116
Loa Loa (eye worm) hypothetical protein 0.0093 0.0315 0.0688
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0075 0.0243 0.0591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Onchocerca volvulus 0.0051 0.0145 0.0278
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0016 0.003
Loa Loa (eye worm) fatty acid synthase 0.0671 0.266 0.5812
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0104 0.036 0.088
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0275 0.1053 0.2587
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0003 0.004
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0201 0.0753 0.1646
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0015 0.0245
Leishmania major protein kinase, putative 0.0016 0.0003 0.0038
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0659 0.2612 0.6428
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.007 0.0154
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0009 0.0017
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0014 0.0025
Leishmania major acyl carrier protein, putative 0.0069 0.0216 0.281
Trypanosoma brucei unspecified product 0.0016 0.0002 0.0034
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0069 0.0216 0.0472
Leishmania major zinc binding dehydrogenase-like protein 0.0042 0.0109 0.1414
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0032 0.0436
Schistosoma mansoni cpg binding protein 0.006 0.0179 0.0322
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0042 0.0109 0.149
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0054 0.0157 0.0343
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.0488 0.1065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0488 0.0877
Mycobacterium tuberculosis Polyketide synthase Pks13 0.1017 0.4061 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Schistosoma mansoni alcohol dehydrogenase 0.0042 0.0109 0.0195
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.007 0.007
Mycobacterium tuberculosis Hypothetical protein 0.0205 0.0768 0.1885
Loa Loa (eye worm) acetyltransferase 0.0147 0.0534 0.1167
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0009 0.0009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0031 0.057
Onchocerca volvulus 0.0023 0.0031 0.0045
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0133 0.1727
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0113 0.0397 0.0713
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0182 0.0353
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0042 0.0109 0.149
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0722 0.2868 0.7056
Echinococcus granulosus GPCR family 2 0.0093 0.0315 0.0566
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0015 0.0141
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0031 0.006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0107 0.0372 0.0812
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0052 0.0147 0.0147
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0069 0.0216 0.0418
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0488 0.0488
Echinococcus granulosus AMP dependent ligase 0.007 0.022 0.0395
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0073 0.0998
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0002 0.0034
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0171 0.063 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0133 0.0239
Echinococcus multilocularis geminin 0.0853 0.3396 0.3396
Brugia malayi PAS domain containing protein 0.0016 0.0003 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.009 0.0161
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Brugia malayi Coelomocyte uptake defective protein 5 0.0064 0.0198 0.0383
Mycobacterium tuberculosis Probable oxidoreductase 0.0042 0.0109 0.0259
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0043 0.0111 0.0257
Brugia malayi jmjC domain containing protein 0.0061 0.0186 0.0361
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0032 0.0414
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.0156 0.0341
Brugia malayi MH1 domain containing protein 0.0033 0.007 0.0136
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0062 0.0215
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.068 0.2696 0.6637
Loa Loa (eye worm) hypothetical protein 0.0042 0.0109 0.0237
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.0009 0.0018
Echinococcus granulosus cathepsin l1 0.0051 0.0145 0.0261
Mycobacterium ulcerans oxidoreductase 0.0042 0.0109 0.025
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0022 0.03
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0038 0.009 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0015 0.0212
Loa Loa (eye worm) hypothetical protein 0.0104 0.036 0.0788
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0003 0.004
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0547 0.2157 0.5309
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0006 0.0082
Loa Loa (eye worm) DR-78 0.0018 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Loa Loa (eye worm) hypothetical protein 0.0042 0.0109 0.0237
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0534 0.0534
Entamoeba histolytica hypothetical protein 0.0107 0.0373 0.9387
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0062 0.0111
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0113 0.0397 0.5106
Brugia malayi MH1 domain containing protein 0.0018 0.0011 0.0021
Plasmodium vivax vivapain-2 0.0051 0.0145 0.2305
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0182 0.0441
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0031 0.0068
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0015 0.0168
Schistosoma mansoni hypothetical protein 0.0093 0.0315 0.0566
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0031 0.0068
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0038 0.0091 0.0177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.009 0.0161
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0044 0.0608
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0044 0.0608
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Onchocerca volvulus Bile acid receptor homolog 0.0038 0.009 0.0164
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0488 0.0877
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0173 0.031
Leishmania major protein kinase, putative 0.002 0.0019 0.0245
Chlamydia trachomatis acyl carrier protein 0.0069 0.0216 0.3398
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0098 0.1175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Leishmania major cathepsin L-like protease 0.0195 0.0729 0.9492
Loa Loa (eye worm) hypothetical protein 0.005 0.0139 0.0303
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0038 0.009 0.0161
Brugia malayi Latrophilin receptor protein 2 0.0093 0.0315 0.0609
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0642 0.2543 0.5556
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0032 0.0436
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0031 0.0058
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0015 0.0245
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0093 0.0315 0.0566
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0171 0.063 0.1536
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0032 0.0057
Loa Loa (eye worm) hypothetical protein 0.0034 0.0076 0.0167
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Loa Loa (eye worm) mucolipin 1 0.0064 0.0198 0.0433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0009 0.0067
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0093 0.0315 0.0566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0729 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0182 0.0328
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0015 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0006 0.0082
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0009 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0145 0.1606
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0016
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.0009 0.0016
Schistosoma mansoni smad1 5 8 and 0.0033 0.007 0.0127
Leishmania major cathepsin L-like protease 0.0051 0.0145 0.1889
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0093 0.0315 0.0315
Leishmania major cathepsin L-like protease 0.0051 0.0145 0.1889
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0173 0.0173
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0038 0.009 0.0164
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0015 0.002
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0003 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Loa Loa (eye worm) hypothetical protein 0.0043 0.0111 0.0243
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0171 0.063 0.063
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0171 0.063 0.1133
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0105 0.0364 0.5783
Toxoplasma gondii exonuclease III APE 0.0019 0.0015 0.0054
Brugia malayi Cathepsin L-like precursor 0.0051 0.0145 0.0281
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0038 0.009 0.0196
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0186 0.0335
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0042 0.0109 0.1414
Brugia malayi hypothetical protein 0.0038 0.009 0.0175
Schistosoma mansoni lamin 0.0107 0.0372 0.0668
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.068 0.2696 0.6637
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0454 0.0817
Onchocerca volvulus Fatty acid synthase homolog 0.1226 0.4911 1
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0171 0.063 0.1219
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0031 0.006
Schistosoma mansoni zinc finger protein 0.0018 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0196
Onchocerca volvulus Putative alcohol dehydrogenase 0.0042 0.0109 0.0203
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0044 0.0086
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0009 0.0122
Brugia malayi Phosphopantetheine attachment site family protein 0.0069 0.0216 0.0418
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0489 0.1919 0.4722
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0009 0.0124
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0003 0.004
Schistosoma mansoni acyl carrier protein 0.0069 0.0216 0.0388
Onchocerca volvulus Protein ultraspiracle homolog 0.0038 0.009 0.0164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0038 0.009 0.0196
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0216 0.0524
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0042 0.0109 0.0195
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0038 0.009 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0062 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0038 0.009 0.0173
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0031 0.0058
Echinococcus granulosus expressed protein 0.0034 0.0076 0.0137
Echinococcus granulosus cpg binding protein 0.0063 0.0193 0.0347
Onchocerca volvulus 0.0051 0.0145 0.0278
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0547 0.2157 0.5304
Entamoeba histolytica cysteine protease, putative 0.0026 0.0044 0.0914
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0044 0.008
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0038 0.009 0.0173
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0145 0.0145
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0729 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0133 0.2107
Onchocerca volvulus 0.0107 0.0372 0.0739
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0722 0.2868 0.7059
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0002 0.0034
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0009 0.0016
Plasmodium vivax SET domain protein, putative 0.0031 0.0062 0.098
Mycobacterium tuberculosis Probable thioesterase TesA 0.0567 0.2236 0.5503
Plasmodium vivax hypothetical protein, conserved 0.0105 0.0364 0.5783
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.0009 0.0009
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0098 0.1558
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0038 0.009 0.009
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0145 0.199
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0073 0.1648
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0488 0.0877
Plasmodium falciparum acyl carrier protein 0.0069 0.0216 0.3429
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0042 0.0109 0.025
Onchocerca volvulus Huntingtin homolog 0.0119 0.0422 0.0842
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0145 0.0145
Brugia malayi hypothetical protein 0.0696 0.2762 0.5346
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0018 0.0034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0197
Onchocerca volvulus 0.0107 0.0372 0.0739
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0009 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0032 0.0436
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0018 0.0032
Brugia malayi hypothetical protein 0.0107 0.0373 0.0722
Brugia malayi Cathepsin L-like precursor 0.0034 0.0076 0.0148

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0029 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 5.0119 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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