Detailed information for compound 1540695

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 340.373 | Formula: C19H20N2O4
  • H donors: 2 H acceptors: 4 LogP: 1.83 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)CCC1=NCCn2c1ccc2.OC(=O)/C=C\C(=O)O
  • InChi: 1S/C15H16N2.C4H4O4/c1-2-5-13(6-3-1)8-9-14-15-7-4-11-17(15)12-10-16-14;5-3(6)1-2-4(7)8/h1-7,11H,8-10,12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
  • InChiKey: SBKCQHWUUXCELP-BTJKTKAUSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni smad1 5 8 and 0.0021 0.0024 0.0059
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.009 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0032 0.0089 0.0216
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.0041 0.0987
Echinococcus multilocularis lamin 0.0044 0.0164 0.0164
Schistosoma mansoni intermediate filament proteins 0.0044 0.0164 0.0399
Schistosoma mansoni [ACP] S-malonyltransferase 0.004 0.0137 0.0332
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0087 0.0704
Brugia malayi Cathepsin L-like precursor 0.0018 0.0006 0.0008
Echinococcus granulosus tumor protein p63 0.029 0.1668 0.4052
Leishmania major zinc-binding dehydrogenase-like protein 0.0039 0.0133 0.1065
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0629 0.374 0.6604
Echinococcus granulosus cathepsin L 0.0028 0.0068 0.0165
Loa Loa (eye worm) hypothetical protein 0.004 0.0137 0.0215
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0136 0.1121
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0039 0.0133 0.0776
Loa Loa (eye worm) hypothetical protein 0.0398 0.2331 0.3668
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0024 0.0041 0.0285
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0587 0.3488 0.6176
Onchocerca volvulus 0.0044 0.0164 0.024
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0046 0.0173 0.024
Brugia malayi Latrophilin receptor protein 2 0.004 0.0142 0.0197
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0032 0.0089 0.0694
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0032 0.0089 0.0089
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0032 0.0089 0.0216
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0077 0.0365 0.2178
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0629 0.374 0.6624
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0055 0.0229 0.1887
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0032 0.0089 0.072
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0089 0.0205
Entamoeba histolytica P-glyco protein 6, putative 0.0077 0.0365 0.9655
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0017 0.0017
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0077 0.0365 0.2178
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Loa Loa (eye worm) hypothetical protein 0.0295 0.17 0.2675
Mycobacterium ulcerans polyketide synthase 0.0668 0.3979 0.7043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0133 0.078
Mycobacterium ulcerans aldehyde dehydrogenase 0.0055 0.0229 0.0377
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.009 0.0516
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0041
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0197 0.1102 0.1942
Trypanosoma cruzi oxidoreductase, putative 0.0039 0.0133 0.109
Leishmania major hypothetical protein, conserved 0.0032 0.0089 0.0694
Leishmania major cathepsin L-like protease 0.0055 0.0232 0.1911
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0017 0.0111
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0495 0.0689
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.009 0.0698
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0087 0.0678
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0173 0.0173
Echinococcus granulosus cathepsin l cysteine peptidase 0.0055 0.0232 0.0564
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0028 0.0067 0.0534
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0039 0.0133 0.0209
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.009 0.0445 0.518
Trypanosoma brucei Flagellar Member 6 0.0032 0.0089 0.0694
Loa Loa (eye worm) hypothetical protein 0.0398 0.2331 0.3668
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0039 0.0133 0.0205
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0039 0.0133 0.0222
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0024 0.0041 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0091 0.0526
Trichomonas vaginalis ABC transporter, putative 0.0077 0.0365 0.2178
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0039 0.0133 0.3441
Brugia malayi Smad1 0.0021 0.0024 0.0034
Echinococcus multilocularis lamin dm0 0.0044 0.0164 0.0164
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Entamoeba histolytica hypothetical protein 0.0073 0.0341 0.9019
Mycobacterium ulcerans polyketide synthase Pks9 0.0416 0.2437 0.4302
Echinococcus multilocularis Protein lozenge 0.005 0.02 0.02
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0046 0.0173 0.0272
Leishmania major oxidoreductase, putative 0.0039 0.0133 0.1065
Loa Loa (eye worm) hypothetical protein 0.0128 0.0677 0.1065
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.004 0.0142 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0039 0.0133 0.0776
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0136 0.1096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0115 0.0669
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0024 0.0041 0.0283
Treponema pallidum acyl carrier protein 0.0064 0.0282 1
Brugia malayi isocitrate dehydrogenase 0.0019 0.0008 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0188 0.1109
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0158 0.0859 1
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0024 0.0041 0.0285
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0032 0.0089 0.0089
Trypanosoma cruzi multidrug resistance protein E, putative 0.0024 0.0041 0.0313
Echinococcus multilocularis geminin 0.0573 0.34 0.34
Giardia lamblia Methyltransferase like 2 0.0189 0.1053 1
Loa Loa (eye worm) acetyltransferase 0.0293 0.1688 0.2656
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0008 0.0018
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0024 0.0041 0.0285
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0089 0.0513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0068 0.0515
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0128 0.0677 0.0942
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0024 0.0041 0.0313
Leishmania major nuclear receptor binding factor-like protein 0.0039 0.0133 0.1065
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0026 0.0063
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0032 0.0089 0.0089
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0026 0.0157
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0038
Schistosoma mansoni hypothetical protein 0.0064 0.0282 0.0686
Leishmania major cysteine peptidase A (CPA) 0.0055 0.0232 0.1911
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0045 0.0525
Echinococcus granulosus dnaJ subfamily B 0.0401 0.2349 0.5705
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0629 0.374 0.5206
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0128 0.0677 0.1065
Schistosoma mansoni multidrug resistance protein 0.0024 0.0041 0.01
Schistosoma mansoni cathepsin s 0.0018 0.0006 0.0014
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0026 0.0026
Mycobacterium ulcerans hypothetical protein 0.0032 0.0089 0.0128
Echinococcus granulosus dna polymerase eta 0.0022 0.0026 0.0063
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0032 0.0089 0.0089
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0041 0.0041
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0032 0.0089 0.0513
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0026 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0173 0.042
Treponema pallidum catabolite gene activator 0.0032 0.0089 0.271
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0254 0.1449 0.2558
Loa Loa (eye worm) phosphatidylinositol 3 0.0055 0.0231 0.0364
Echinococcus granulosus multidrug resistance protein 1 0.0054 0.0222 0.054
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0008 0.0028
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0024 0.0041 0.0285
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0064 0.0282 0.3148
Leishmania major zinc binding dehydrogenase-like protein 0.0039 0.0133 0.1065
Entamoeba histolytica hypothetical protein 0.0073 0.0341 0.9019
Loa Loa (eye worm) hypothetical protein 0.0044 0.0164 0.0258
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0055 0.0229 0.0394
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.2349 0.2349
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0089 0.0205
Brugia malayi hypothetical protein 0.0024 0.0041 0.0057
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0111 0.0125
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0158 0.0859 0.2144
Echinococcus granulosus TGF beta signal transducer SmadC 0.0021 0.0024 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Loa Loa (eye worm) hypothetical protein 0.0236 0.1337 0.2103
Plasmodium vivax vivapain-1 0.0028 0.0068 0.0793
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0077 0.0365 0.0634
Trypanosoma cruzi cruzipain precursor, putative 0.0211 0.1183 1
Brugia malayi P-glycoprotein-like protein 0.0024 0.0041 0.0057
Schistosoma mansoni alcohol dehydrogenase 0.0039 0.0133 0.0322
Mycobacterium tuberculosis Conserved hypothetical protein 0.0064 0.0282 0.0488
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0173 0.042
Echinococcus granulosus multidrug resistance protein 1 0.0054 0.0222 0.054
Loa Loa (eye worm) Smad1 0.0021 0.0024 0.0038
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0041 0.0223
Echinococcus granulosus hyperpolarization activated cyclic 0.069 0.4118 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0365 0.0574
Schistosoma mansoni [ACP] S-malonyltransferase 0.004 0.0137 0.0332
Toxoplasma gondii type I fatty acid synthase, putative 0.0668 0.3979 1
Trypanosoma cruzi cysteine peptidase, putative 0.0211 0.1183 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0055 0.0232 0.2702
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0173 0.042
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0089 0.0205
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0039 0.0133 0.0164
Leishmania major hypothetical protein, conserved 0.0189 0.1053 0.889
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0168 0.0409
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0077 0.0365 0.0365
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.004 0.0137 0.159
Onchocerca volvulus 0.0032 0.0089 0.0131
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0041 0.0084
Loa Loa (eye worm) cysteine protease 0.0055 0.0232 0.0365
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0077 0.0365 0.2178
Mycobacterium leprae conserved hypothetical protein 0.0064 0.0282 0.0431
Brugia malayi Cytochrome P450 family protein 0.0035 0.0108 0.015
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0173 0.042
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0039 0.0133 0.0205
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0017 0.0202
Schistosoma mansoni hypothetical protein 0.0401 0.2349 0.5705
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Plasmodium falciparum cGMP-dependent protein kinase 0.0032 0.0089 0.1037
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0017 0.0202
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.004 0.0137 0.0137
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0168 0.0168
Mycobacterium tuberculosis Possible dehydrogenase 0.0039 0.0133 0.0222
Schistosoma mansoni survival motor neuron protein 0.0098 0.0495 0.1202
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0032 0.0089 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0173 0.042
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0065
Giardia lamblia GTOR 0.0055 0.0231 0.2068
Schistosoma mansoni ap endonuclease 0.002 0.0017 0.0042
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0408 0.2389 0.5996
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0609 0.3622 0.6415
Mycobacterium ulcerans oxidoreductase FadB5 0.0039 0.0133 0.0205
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0039 0.0133 0.0222
Loa Loa (eye worm) AGC/PKG protein kinase 0.0032 0.0089 0.014
Schistosoma mansoni hypothetical protein 0.0402 0.2353 0.5714
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Brugia malayi hypothetical protein 0.0482 0.2841 0.3954
Loa Loa (eye worm) hypothetical protein 0.0096 0.0478 0.0753
Trichomonas vaginalis abcb9, putative 0.0077 0.0365 0.2178
Toxoplasma gondii acyl carrier protein ACP 0.0064 0.0282 0.0692
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0017 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0133 0.078
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0064 0.0282 0.0471
Schistosoma mansoni multidrug resistance protein 0.0077 0.0365 0.0886
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0006 0.0008
Leishmania major hypothetical protein, conserved 0.0032 0.0089 0.0694
Mycobacterium ulcerans acyl-CoA synthetase 0.0064 0.0282 0.0471
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0032 0.0237
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0077 0.0365 0.2178
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0024 0.0041 0.0313
Toxoplasma gondii FATC domain-containing protein 0.0035 0.0105 0.0245
Brugia malayi hypothetical protein 0.0073 0.0341 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0188 0.1109
Loa Loa (eye worm) hypothetical protein 0.0028 0.0067 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Loa Loa (eye worm) hypothetical protein 0.0086 0.0423 0.0665
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0064 0.0282 0.0431
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0055 0.0232 0.0365
Echinococcus granulosus Ion_trans_N domain containing protein 0.0402 0.2353 0.5714
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0024 0.0041 0.0285
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0055 0.0231 0.0322
Schistosoma mansoni smdr1 0.0024 0.0041 0.01
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0357 0.2081 0.3679
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0077 0.0365 0.2178
Loa Loa (eye worm) hypothetical protein 0.0039 0.0133 0.0209
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0049 0.0191 0.0464
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0089 0.0145
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0096 0.0484 0.0845
Brugia malayi hypothetical protein 0.0398 0.2331 0.3244
Echinococcus multilocularis mothers against decapentaplegic 5 0.0021 0.0024 0.0024
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0077 0.0365 0.0365
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0668 0.3979 0.7043
Mycobacterium leprae Polyketide synthase Pks13 0.094 0.5643 1
Entamoeba histolytica P-glycoprotein-1 0.0077 0.0365 0.9655
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0008 0.0011
Plasmodium vivax acyl carrier protein, putative 0.0064 0.0282 0.3286
Brugia malayi MH2 domain containing protein 0.0021 0.0024 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0378 0.4394
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0087 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Leishmania major cathepsin L-like protease 0.0211 0.1183 1
Echinococcus granulosus cpg binding protein 0.003 0.0076 0.0185
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0045 0.0525
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0089 0.0513
Trypanosoma brucei oxidoreductase, putative 0.0039 0.0133 0.1065
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.009 0.0218
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0055 0.0231 0.1927
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0017 0.0111
Echinococcus multilocularis cysteine protease 0.0055 0.0232 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0668 0.3979 0.7043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0136 0.1414
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Schistosoma mansoni cellular tumor antigen P53 0.0042 0.0154 0.0373
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0055 0.0231 0.0562
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0189
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.009 0.0698
Onchocerca volvulus 0.0098 0.0495 0.0725
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0007
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0091 0.0526
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Trypanosoma brucei p-glycoprotein 0.0024 0.0041 0.0285
Brugia malayi Phosphopantetheine attachment site family protein 0.0064 0.0282 0.0393
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0158 0.0859 0.1196
Trypanosoma cruzi cysteine proteinase, putative 0.0028 0.0068 0.0541
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0111 0.0183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0028 0.0068 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0188 0.1109
Echinococcus granulosus lamin dm0 0.0044 0.0164 0.0399
Brugia malayi Cathepsin L-like precursor 0.0055 0.0232 0.0323
Loa Loa (eye worm) hypothetical protein 0.0077 0.0365 0.0574
Schistosoma mansoni hypothetical protein 0.0073 0.0341 0.0828
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0046 0.0173 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0055 0.0232 0.0564
Loa Loa (eye worm) hypothetical protein 0.004 0.0142 0.0223
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0032 0.0089 0.0089
Mycobacterium ulcerans quinone oxidoreductase 0.0039 0.0133 0.0205
Leishmania major p-glycoprotein e 0.0024 0.0041 0.0285
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0096 0.0484 0.0845
Echinococcus granulosus multidrug resistance protein 1 0.0077 0.0365 0.0886
Plasmodium falciparum multidrug resistance protein 2 0.0024 0.0041 0.0479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0629 0.374 0.6618
Loa Loa (eye worm) acyl carrier protein 0.0289 0.1663 0.2616
Loa Loa (eye worm) hypothetical protein 0.0042 0.0154 0.0242
Brugia malayi AMP-binding enzyme family protein 0.0587 0.3488 0.4854
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0046 0.0173 0.042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0026 0.0185
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.009 0.009
Brugia malayi hypothetical protein 0.0096 0.0478 0.0666
Schistosoma mansoni multidrug resistance protein 0.0077 0.0365 0.0886
Schistosoma mansoni smad1 5 8 and 0.0021 0.0024 0.0059
Brugia malayi ABC transporter 0.0023 0.0036 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.009 0.0516
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0055 0.0231 0.1904
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0032 0.0089 0.0216
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0024 0.0041 0.01
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0039 0.0133 0.0185
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0045 0.0525
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0024 0.0041 0.0479
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0039 0.0133 0.0205
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0064 0.0282 0.0488
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0017 0.0083
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0096 0.0484 0.079
Onchocerca volvulus Putative alcohol dehydrogenase 0.0039 0.0133 0.0194
Schistosoma mansoni lamin 0.0044 0.0164 0.0399
Loa Loa (eye worm) hypothetical protein 0.0096 0.0478 0.0753
Mycobacterium ulcerans transmembrane transport protein 0.0032 0.0089 0.0128
Treponema pallidum cyclic nucleotide binding protein 0.0032 0.0089 0.271
Schistosoma mansoni aldehyde dehydrogenase 0.0055 0.0229 0.0557
Echinococcus granulosus serine protein kinase ATM 0.0035 0.0105 0.0255
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.004 0.0137 0.1417
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0023 0.0036 0.018
Onchocerca volvulus 0.0055 0.0232 0.034
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0089 0.0086
Schistosoma mansoni hypothetical protein 0.004 0.0142 0.0344
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0036 0.0192
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0039 0.0133 0.109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0288 0.1659 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0231 0.1373
Leishmania major cathepsin L-like protease 0.0211 0.1183 1
Toxoplasma gondii acyl transferase domain-containing protein 0.004 0.0137 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0189 0.1053 0.6337
Leishmania major hypothetical protein, unknown function 0.0032 0.0089 0.0694
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0046 0.0173 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.009 0.0516
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0668 0.3979 0.703
Mycobacterium ulcerans dehydrogenase 0.0039 0.0133 0.0205
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0032 0.0089 0.0216
Echinococcus granulosus histone acetyltransferase KAT2B 0.0086 0.0422 0.1024
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0055 0.0232 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Leishmania major DNA polymerase eta, putative 0.0022 0.0026 0.0157
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0041 0.0084
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0039 0.0133 0.0133
Mycobacterium leprae Probable oxidireductase 0.0039 0.0133 0.0164
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0032 0.0089 0.0216
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0087 0.0704
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0017 0.0042
Echinococcus granulosus Smad4 0.0021 0.0024 0.0059
Echinococcus granulosus histone acetyltransferase KAT2B 0.0285 0.1638 0.3978
Trypanosoma cruzi cysteine peptidase, putative 0.0211 0.1183 1
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0039 0.0133 0.0222
Plasmodium vivax multidrug resistance protein 2, putative 0.0024 0.0041 0.0479
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0064 0.0282 0.0488
Echinococcus granulosus multidrug resistance associated protein 1 0.0024 0.0041 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0068 0.0386
Loa Loa (eye worm) hypothetical protein 0.0096 0.0484 0.0761
Trypanosoma brucei acyl transferase-like protein 0.004 0.0137 0.1098
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Brugia malayi Methyltransferase-like protein 4 0.0189 0.1053 0.1465
Echinococcus granulosus smad 0.0021 0.0024 0.0059
Toxoplasma gondii aldehyde dehydrogenase 0.0055 0.0229 0.0558
Plasmodium falciparum cysteine proteinase falcipain 1 0.0028 0.0068 0.0793
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0039 0.0133 0.1065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Onchocerca volvulus 0.0055 0.0232 0.034
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0236 0.1337 0.1958
Entamoeba histolytica ABC transporter, putative 0.0024 0.0041 0.0987
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0506 0.2989 0.5282
Trichomonas vaginalis bromodomain-containing protein, putative 0.0086 0.0422 0.2522
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0068 0.171
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0024 0.0041 0.0065
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0026 0.0157
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0193 0.1076 0.1897
Loa Loa (eye worm) MH2 domain-containing protein 0.0021 0.0024 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0077 0.0365 0.2178
Mycobacterium ulcerans acyl carrier protein 0.0064 0.0282 0.0471
Echinococcus granulosus lamin 0.0044 0.0164 0.0399
Trichomonas vaginalis abcb9, putative 0.0077 0.0365 0.2178
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0629 0.374 0.6624
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0188 0.1109
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.012 0.0292
Trypanosoma cruzi protein kinase A regulatory subunit 0.0032 0.0089 0.072
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.009 0.0698
Toxoplasma gondii ABC transporter family protein 0.0024 0.0041 0.0084
Schistosoma mansoni eyes absent homolog 0.0086 0.0423 0.1027
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0039 0.0133 0.1065
Toxoplasma gondii target of rapamycin (TOR), putative 0.0046 0.0177 0.0426
Schistosoma mansoni hypothetical protein 0.004 0.0142 0.0344
Mycobacterium ulcerans polyketide synthase 0.0629 0.374 0.6618
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0026 0.0132
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0055 0.0231 0.6086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.003
Leishmania major protein kinase, putative 0.0032 0.0089 0.0694
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0146 0.0857
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0055 0.0229 0.0229
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0077 0.0365 0.3038
Entamoeba histolytica P-glycoprotein-2, putative 0.0077 0.0365 0.9655
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0032 0.0089 0.0216
Mycobacterium tuberculosis Possible dehydrogenase 0.0039 0.0133 0.0222
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.1056 0.6356 1
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.0004 0.0004
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0136 0.3539
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0018 0.0006 0.0008
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0064 0.0282 0.0413
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0064 0.0282 0.2359
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0077 0.0365 0.3578
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0136 0.1096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0177 0.1043
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0158 0.0859 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0039 0.0133 0.0185
Plasmodium vivax vivapain-2 0.0055 0.0232 0.2702
Echinococcus multilocularis expressed conserved protein 0.0032 0.0089 0.0089
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0032 0.0089 0.0216
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0045 0.0346
Mycobacterium ulcerans oxidoreductase 0.0039 0.0133 0.0205
Echinococcus granulosus patatin phospholipase domain containing protein 0.0032 0.0089 0.0216
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0064 0.0282 0.0471
Loa Loa (eye worm) hypothetical protein 0.0039 0.0133 0.0209
Trypanosoma cruzi cysteine peptidase, putative 0.0055 0.0232 0.1933
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0133 0.078
Brugia malayi ABC transporter family protein 0.0024 0.0041 0.0057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0008 0.0008
Schistosoma mansoni multidrug resistance protein 0.0023 0.0036 0.0087
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0039 0.0133 0.0222
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Brugia malayi Cathepsin L-like precursor 0.0055 0.0232 0.0323
Brugia malayi Inositol-1 0.004 0.0136 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0068 0.0386
Brugia malayi Cytochrome P450 family protein 0.0032 0.0087 0.0122
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0158 0.0859 0.7246
Onchocerca volvulus 0.0077 0.0365 0.0534
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0168 0.0168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0066 0.0104
Echinococcus granulosus muscleblind protein 0.0295 0.17 0.4129
Schistosoma mansoni inositol monophosphatase 0.004 0.0136 0.0331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0144 0.0847
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0026 0.0036
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0341 0.0828
Trichomonas vaginalis ABC transporter, putative 0.0077 0.0365 0.2178
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0024 0.0041 0.0313
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0055 0.0231 0.1904
Trypanosoma cruzi cAMP response protein 1 0.0032 0.0089 0.072
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0024 0.0041 0.0313
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0089 0.072
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0017 0.0079
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0032 0.0089 0.0216
Echinococcus multilocularis musashi 0.0044 0.0164 0.0164
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0086 0.0422 0.2522
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0032 0.0089 0.0145
Leishmania major protein kinase, putative 0.0032 0.0089 0.0694
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0609 0.3622 0.6415
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0021 0.0024 0.0024
Plasmodium falciparum ABC transporter B family member 7, putative 0.0024 0.0041 0.0479
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Trypanosoma brucei protein kinase A regulatory subunit 0.0032 0.0089 0.0694
Brugia malayi Intermediate filament tail domain containing protein 0.0044 0.0164 0.0228
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0039 0.0133 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.012 0.0701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0177 0.1043
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0017 0.0027
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0039 0.0133 0.109
Echinococcus multilocularis smad 0.0021 0.0024 0.0024
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0036 0.0849
Schistosoma mansoni aldehyde dehydrogenase 0.0055 0.0229 0.0557
Loa Loa (eye worm) ABC transporter 0.0024 0.0041 0.0065
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0036 0.0192
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0068 0.171
Echinococcus granulosus cathepsin l1 0.0055 0.0232 0.0564
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0068 0.171
Schistosoma mansoni smad1 5 8 and 0.0021 0.0024 0.0059
Entamoeba histolytica P-glycoprotein-2 0.0077 0.0365 0.9655
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0629 0.374 0.6604
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0039 0.0133 0.0205
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0032 0.0089 0.0124
Mycobacterium leprae Probable polyketide synthase Pks1 0.0668 0.3979 0.703
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0032 0.0089 0.0205
Loa Loa (eye worm) fibroinase 0.0055 0.0232 0.0365
Brugia malayi hypothetical protein 0.0086 0.0423 0.0588
Schistosoma mansoni hypothetical protein 0.0087 0.0429 0.1042
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0026 0.0033
Leishmania major hypothetical protein, conserved 0.0032 0.0089 0.0694
Mycobacterium tuberculosis Conserved protein 0.0032 0.0089 0.0145
Brugia malayi Cathepsin L-like precursor 0.0055 0.0232 0.0323
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0055 0.0231 0.6086
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0039 0.0133 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0064 0.0282 0.0471
Treponema pallidum cyclic nucleotide binding protein 0.0032 0.0089 0.271
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0087 0.0137
Mycobacterium ulcerans polyketide synthase MbtC 0.0158 0.0859 0.1497
Entamoeba histolytica cysteine proteinase 2 0.0028 0.0068 0.171
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0041 0.0084
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0293 0.1688 0.1688
Loa Loa (eye worm) MH2 domain-containing protein 0.0313 0.1808 0.2844
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0032 0.0089 0.0216
Echinococcus granulosus survival motor neuron protein 1 0.0482 0.2841 0.6899
Echinococcus multilocularis Smad4 0.0021 0.0024 0.0024
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0077 0.0365 0.0365
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Echinococcus multilocularis hyperpolarization activated cyclic 0.069 0.4118 0.4118
Schistosoma mansoni lozenge 0.005 0.02 0.0485
Schistosoma mansoni Smad4 0.0021 0.0024 0.0059
Loa Loa (eye worm) hypothetical protein 0.0076 0.036 0.0566
Plasmodium vivax ABC transporter B family member 3, putative 0.0024 0.0041 0.0479
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.009 0.0218
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0055 0.0231 0.0562
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0105 0.0146
Brugia malayi Cathepsin L-like precursor 0.0055 0.0232 0.0323
Mycobacterium ulcerans hypothetical protein 0.0032 0.0089 0.0128
Plasmodium vivax ABC transporter B family member 6, putative 0.0024 0.0041 0.0479
Plasmodium vivax multidrug resistance protein 1, putative 0.0077 0.0365 0.4244
Onchocerca volvulus 0.0055 0.0232 0.034
Plasmodium vivax ABC transporter B family member 7, putative 0.0024 0.0041 0.0479
Schistosoma mansoni hypothetical protein 0.0573 0.34 0.8256
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.0004 0.001
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0026 0.0157
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.0041 0.0987
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0024 0.0041 0.0285
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.004 0.0137 0.159
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.004 0.0142 0.0142
Echinococcus granulosus microtubule associated protein 2 0.0677 0.4036 0.9802
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0039 0.0133 0.0222
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0017 0.0017
Brugia malayi multidrug resistance related protein 1 0.0024 0.0041 0.0057
Mycobacterium ulcerans fatty acid synthase Fas 0.0197 0.1102 0.1928
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0318 0.1838 0.4608
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0668 0.3979 0.703
Toxoplasma gondii quinone oxidoreductase, putative 0.0039 0.0133 0.0315
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0036 0.0849
Brugia malayi MH1 domain containing protein 0.0021 0.0024 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0087 0.0137
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.009 0.0125
Leishmania major cathepsin L-like protease 0.0211 0.1183 1
Plasmodium falciparum ABC transporter B family member 6, putative 0.0024 0.0041 0.0479
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0024 0.0041 0.0084
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.004 0.0142 0.0344
Leishmania major hypothetical protein, conserved 0.004 0.0137 0.1098
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0232 0.0564
Brugia malayi Alcohol dehydrogenase class III 0.0039 0.0133 0.0185
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0064 0.0282 0.0488
Schistosoma mansoni hypothetical protein 0.0098 0.0495 0.1202
Mycobacterium ulcerans quinone oxidoreductase 0.0039 0.0133 0.0205
Echinococcus granulosus ATP binding cassette sub family B 0.0023 0.0036 0.0087
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0032 0.0089 0.0089
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0045 0.0094
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0168 0.0409
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0023 0.0036 0.0087
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0452 0.2657 0.4702
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0032 0.0089 0.0694
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0055 0.0232 0.2702
Brugia malayi Cathepsin L-like precursor 0.0055 0.0232 0.0323
Entamoeba histolytica acyl-CoA synthetase, putative 0.0064 0.0282 0.7449
Schistosoma mansoni multidrug resistance protein 0.0077 0.0365 0.0886
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.009 0.0725
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0264 0.0647
Leishmania major quinone oxidoreductase, putative 0.0039 0.0133 0.1065
Schistosoma mansoni multidrug resistance protein 0.0024 0.0041 0.01
Loa Loa (eye worm) hypothetical protein 0.0046 0.0173 0.0272
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0026 0.0016
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0064 0.0282 0.0471
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0057
Loa Loa (eye worm) hypothetical protein 0.0295 0.17 0.2675
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0024 0.0041 0.0059
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0032 0.0089 0.1037
Brugia malayi ABC transporter transmembrane region family protein 0.0024 0.0041 0.0057
Onchocerca volvulus 0.0044 0.0164 0.024
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0032 0.0089 0.072
Trichomonas vaginalis ABC transporter, putative 0.0077 0.0365 0.2178
Echinococcus granulosus acyl carrier protein mitochondrial 0.0064 0.0282 0.0686
Echinococcus multilocularis dna polymerase eta 0.0022 0.0026 0.0026
Trypanosoma cruzi major cysteine proteinase, putative 0.0166 0.0907 0.7659
Schistosoma mansoni [ACP] S-malonyltransferase 0.004 0.0137 0.0332
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0032 0.0089 0.0205
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.004 0.0137 0.019
Loa Loa (eye worm) acyl carrier protein 0.0064 0.0282 0.0444
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0039 0.0133 0.0205
Echinococcus multilocularis multidrug resistance associated protein 7 0.0024 0.0041 0.0041
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0034 0.0104 0.0253
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0039 0.0133 0.0205
Onchocerca volvulus 0.0055 0.0232 0.034
Schistosoma mansoni smad 0.0021 0.0024 0.0059
Brugia malayi Cytochrome P450 family protein 0.0032 0.0087 0.0122
Onchocerca volvulus 0.0055 0.0232 0.034
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0032 0.0089 0.0089
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0046 0.0173 0.0272
Giardia lamblia Hypothetical protein 0.0023 0.0036 0.018
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0039 0.0133 0.109
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0008 0.0088
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.094 0.5643 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0026 0.0185
Echinococcus multilocularis AMP dependent ligase 0.0064 0.0282 0.0282
Mycobacterium ulcerans Type I modular polyketide synthase 0.0629 0.374 0.6618
Mycobacterium ulcerans Type I modular polyketide synthase 0.0629 0.374 0.6618
Mycobacterium tuberculosis Probable oxidoreductase 0.0039 0.0133 0.0222
Leishmania major DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Echinococcus multilocularis hypothetical protein 0.0402 0.2353 0.2353
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0024 0.0041 0.0042
Entamoeba histolytica hypothetical protein 0.0073 0.0341 0.9019
Giardia lamblia DINP protein human, muc B family 0.0022 0.0026 0.0085
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0064 0.0282 0.0488
Trypanosoma cruzi cysteine peptidase, putative 0.0211 0.1183 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0232 0.1378
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0378 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0055 0.0229 0.0377
Mycobacterium ulcerans quinone reductase Qor 0.0039 0.0133 0.0205
Mycobacterium ulcerans polyketide synthase Pks13 0.094 0.5643 1
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0024 0.0041 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0177 0.1043
Schistosoma mansoni smdr2 0.0077 0.0365 0.0886
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0587 0.3488 0.5487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0105 0.0609
Mycobacterium ulcerans Type I modular polyketide synthase 0.0629 0.374 0.6618
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0032 0.0089 0.0694
Trypanosoma brucei multidrug resistance protein E 0.0024 0.0041 0.0285
Trypanosoma cruzi oxidoreductase, putative 0.0039 0.0133 0.109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Trypanosoma brucei oxidoreductase, putative 0.0039 0.0133 0.1065
Leishmania major cathepsin L-like protease 0.0055 0.0232 0.1911
Schistosoma mansoni multidrug resistance protein 0.0024 0.0041 0.01
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0054 0.0222 0.1319
Schistosoma mansoni DNA polymerase eta 0.0022 0.0026 0.0063
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.4036 0.4036
Trypanosoma cruzi acyl transferase-like protein, putative 0.004 0.0137 0.1123
Leishmania major cytochrome p450-like protein 0.0032 0.0087 0.0678
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0524 0.3099 0.5459
Loa Loa (eye worm) hypothetical protein 0.0046 0.0173 0.0272
Schistosoma mansoni lamin 0.0044 0.0164 0.0399
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0039 0.0133 0.0164
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0032 0.0089 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0144 0.0847
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0077 0.0365 0.0886
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0026 0.0185
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0036 0.0192
Brugia malayi Cyclic-nucleotide gated cation channel 0.0046 0.0173 0.024
Entamoeba histolytica P-glycoprotein-2 0.0077 0.0365 0.9655
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0039 0.0133 0.109
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0026 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0232 0.1378
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0041 0.0041
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0077 0.0365 0.0574
Onchocerca volvulus Cathepsin F homolog 0.0055 0.0232 0.034
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0024 0.0041 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0036 0.0192
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0232 0.034
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0039 0.0133 0.0205
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0024 0.0041 0.0479
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0192 0.1071 0.9051
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0158 0.0859 0.2087
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0158 0.0859 0.7246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0188 0.1109
Loa Loa (eye worm) ctsf protein 0.0055 0.0232 0.0365
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0216 0.1216 0.2145
Echinococcus granulosus multidrug resistance protein 1 0.0077 0.0365 0.0886
Echinococcus granulosus multidrug resistance protein 1 0.0077 0.0365 0.0886
Schistosoma mansoni cpg binding protein 0.003 0.0076 0.0185
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0008 0.0008
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0024 0.0041 0.0059
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0168 0.0265
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0173 0.042
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0008 0.0028
Toxoplasma gondii exonuclease III APE 0.002 0.0017 0.0024
Onchocerca volvulus 0.1094 0.6589 0.965
Trichomonas vaginalis abcb9, putative 0.0077 0.0365 0.2178
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0064 0.0282 0.0488
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0087 0.0124
Onchocerca volvulus 0.0587 0.3488 0.5108
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0086 0.0422 0.1042
Echinococcus granulosus AMP dependent ligase 0.0064 0.0282 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0089 0.0216
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0077 0.0365 0.0886
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Trypanosoma brucei unspecified product 0.0022 0.0026 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0064 0.0282 0.0488
Mycobacterium ulcerans acyl carrier protein 0.0064 0.0282 0.0471
Brugia malayi MH2 domain containing protein 0.0313 0.1808 0.2516
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0158 0.0859 0.1497
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0026 0.0584
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0158 0.0859 0.2087
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0008 0.0088
Echinococcus granulosus cGMP dependent protein kinase 0.0032 0.0089 0.0216
Schistosoma mansoni acyl carrier protein 0.0064 0.0282 0.0686
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0177 0.1043
Mycobacterium ulcerans hypothetical protein 0.0064 0.0282 0.0471
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0077 0.0365 0.0886
Echinococcus granulosus cGMP dependent protein kinase 1 0.0032 0.0089 0.0216
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0232 0.6105
Brugia malayi intermediate filament protein 0.0044 0.0164 0.0228
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0136 0.1121
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.009 0.0698
Trichomonas vaginalis ABC transporter, putative 0.0077 0.0365 0.2178
Echinococcus granulosus hyperpolarization activated cyclic 0.069 0.4118 1
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0039 0.0133 0.1371
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0168 0.0409
Schistosoma mansoni ap endonuclease 0.002 0.0017 0.0042
Loa Loa (eye worm) ABC transporter 0.0024 0.0041 0.0065
Onchocerca volvulus 0.0055 0.0232 0.034
Onchocerca volvulus 0.0039 0.0133 0.0194
Entamoeba histolytica acyl-CoA synthetase, putative 0.0064 0.0282 0.7449
Onchocerca volvulus 0.0037 0.012 0.0176
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0077 0.0365 0.2178
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.069 0.4118 1
Echinococcus granulosus intermediate filament protein 0.0044 0.0164 0.0399
Echinococcus multilocularis tumor protein p63 0.029 0.1668 0.1668
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0046 0.0173 0.1018
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0232 0.6105
Trichomonas vaginalis taga, putative 0.0077 0.0365 0.2178
Schistosoma mansoni hypothetical protein 0.004 0.0142 0.0344
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0057
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0041 0.0084
Onchocerca volvulus 0.0042 0.0154 0.0225
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0629 0.374 0.6624
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Trypanosoma cruzi acyl transferase-like protein 0.004 0.0137 0.1123
Toxoplasma gondii type I fatty acid synthase 0.0096 0.0484 0.1199
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.0041 0.0987
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0006 0.0012
Entamoeba histolytica P-glycoprotein 6, putative 0.0024 0.0041 0.0987
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0008 0.0018
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0032 0.0089 0.0216
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0032 0.0089 0.1037
Echinococcus multilocularis survival motor neuron protein 1 0.0482 0.2841 0.2841
Plasmodium falciparum multidrug resistance-associated protein 1 0.0024 0.0041 0.0479
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0158 0.0859 1
Echinococcus multilocularis cathepsin L 0.0028 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0352 0.2049 0.3224
Entamoeba histolytica P-glycoprotein-5 0.0077 0.0365 0.9655
Brugia malayi ABC transporter family protein 0.0024 0.0041 0.0057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0259 0.063
Echinococcus multilocularis GPCR, family 2 0.004 0.0142 0.0142
Plasmodium vivax vivapain-3 0.0028 0.0068 0.0793
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0158 0.0859 0.1352
Schistosoma mansoni zinc binding dehydrogenase 0.0039 0.0133 0.0322
Plasmodium falciparum ABC transporter B family member 5, putative 0.0024 0.0041 0.0479
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0048 0.0188 0.1535
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Plasmodium falciparum acyl carrier protein 0.0064 0.0282 0.3286
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0177 0.1043
Schistosoma mansoni multidrug resistance protein 0.0024 0.0041 0.01
Trypanosoma cruzi cysteine protease, putative 0.0028 0.0068 0.0541
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0158 0.0859 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0028 0.0068 0.0165
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.012 0.3108
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0668 0.3979 0.7048
Plasmodium vivax vivapain-2 0.0055 0.0232 0.2702
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0041 0.0084
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0004 0.001
Echinococcus multilocularis 0.0024 0.0041 0.0041
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0024 0.0039 0.0061
Schistosoma mansoni cpg binding protein 0.003 0.0076 0.0185
Brugia malayi Egg laying defective protein 4 0.0032 0.0089 0.0124
Leishmania major pentamidine resistance protein 1 0.0024 0.0041 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0089 0.0216
Onchocerca volvulus 0.0398 0.2331 0.3414
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0046 0.0173 0.042
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0032 0.0089 0.0513
Plasmodium vivax ABC transporter B family member 5, putative 0.0024 0.0041 0.0479
Brugia malayi ABC transporter transmembrane region family protein 0.0023 0.0036 0.005
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0506 0.2989 0.5282
Loa Loa (eye worm) intermediate filament protein 0.0044 0.0164 0.0258
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0077 0.0365 0.2178
Echinococcus granulosus NADH dehydrogenase 0.0064 0.0282 0.0686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0133 0.0779
Echinococcus granulosus cGMP dependent protein kinase 1 0.0032 0.0089 0.0216
Trypanosoma cruzi cysteine proteinase, putative 0.0028 0.0068 0.0541
Brugia malayi Calcitonin receptor-like protein seb-1 0.0128 0.0677 0.0942
Schistosoma mansoni hypothetical protein 0.0032 0.0089 0.0216
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0032 0.0089 0.0145
Loa Loa (eye worm) hypothetical protein 0.0096 0.0484 0.0761
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.004 0.0137 0.0616
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0009
Leishmania major hypothetical protein, conserved 0.0025 0.0045 0.0319
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0039 0.0133 0.3441
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0064 0.0282 0.2337
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0039 0.0133 0.0205
Brugia malayi MH2 domain containing protein 0.0021 0.0024 0.0034
Plasmodium falciparum ABC transporter B family member 3, putative 0.0024 0.0041 0.0479
Plasmodium falciparum multidrug resistance-associated protein 2 0.0024 0.0041 0.0479
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0028 0.0068 0.0541
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0039 0.0133 0.0315
Plasmodium vivax unspecified product 0.0018 0.0006 0.0066
Loa Loa (eye worm) runx1 0.005 0.02 0.0314
Entamoeba histolytica P-glycoprotein 6, putative 0.0024 0.0041 0.0987
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0032 0.0089 0.1037
Echinococcus granulosus cathepsin l1 0.0037 0.012 0.0292
Entamoeba histolytica ATP-binding cassette protein, putative 0.0024 0.0041 0.0987
Toxoplasma gondii ABC transporter, putative 0.0024 0.0041 0.0084
Giardia lamblia ABC transporter, putative 0.0024 0.0041 0.023
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0068 0.0095
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0024 0.0041 0.0285
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.4036 0.9802
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0136 0.0798
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0168 0.0409
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0032 0.0089 0.014
Toxoplasma gondii cathepsin CPL 0.0055 0.0232 0.0565
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0341 0.0341
Mycobacterium ulcerans thioesterase 0.0524 0.3099 0.5478
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0017 0.0083
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0024 0.0041 0.0285
Onchocerca volvulus Fatty acid synthase homolog 0.1133 0.6828 1
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0089 0.0513
Echinococcus multilocularis serine protein kinase ATM 0.0035 0.0105 0.0105
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0232 0.0232
Mycobacterium ulcerans transcriptional regulatory protein 0.0032 0.0089 0.0128
Echinococcus granulosus mothers against decapentaplegic 5 0.0021 0.0024 0.0059
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0077 0.0365 0.0899
Chlamydia trachomatis acyl carrier protein 0.0064 0.0282 0.2508
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0026 0.0026
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0068 0.0541
Trypanosoma cruzi cruzipain precursor, putative 0.0018 0.0006 0.0012
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0027 0.0061 0.045
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0039 0.0133 0.0222
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0045 0.0319
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0231 0.1373
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0102 0.0593
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0039 0.0133 0.0164
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0136 0.0324
Onchocerca volvulus 0.0055 0.0232 0.034
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0041 0.0041
Loa Loa (eye worm) fatty acid synthase 0.062 0.3689 0.5804
Brugia malayi ABC transporter family protein 0.0024 0.0041 0.0057
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0008 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0045 0.0346
Echinococcus multilocularis ATP binding cassette sub family B 0.0076 0.036 0.036
Loa Loa (eye worm) latrophilin receptor protein 2 0.004 0.0142 0.0223
Echinococcus multilocularis muscleblind protein 0.0295 0.17 0.17
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0168 0.0409
Trypanosoma cruzi cAMP response protein 1, putative 0.0032 0.0089 0.072
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.069 0.4118 1
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.004 0.0137 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.012 0.0701
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0293 0.1688 0.41
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0173 0.0173
Echinococcus granulosus ATP binding cassette sub family B 0.0024 0.0041 0.01
Trypanosoma cruzi oxidoreductase, putative 0.0039 0.0133 0.109
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0046 0.0173 0.042
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0232 0.0232
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.009 0.0725
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0032 0.0089 0.0216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0282 0.0488
Schistosoma mansoni hypothetical protein 0.0573 0.34 0.8256
Loa Loa (eye worm) hypothetical protein 0.0055 0.0232 0.0365
Loa Loa (eye worm) MH1 domain-containing protein 0.0021 0.0024 0.0038
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0039 0.0133 0.109
Brugia malayi AMP-binding enzyme family protein 0.0193 0.1076 0.1498
Brugia malayi ABC transporter 0.0024 0.0041 0.0057
Loa Loa (eye worm) inositol-1 0.004 0.0136 0.0215
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0046 0.0173 0.042
Onchocerca volvulus Huntingtin homolog 0.0096 0.0478 0.0701
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0416 0.2437 0.4302
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0026 0.0157
Entamoeba histolytica hypothetical protein 0.0024 0.0041 0.0987
Loa Loa (eye worm) hypothetical protein 0.0032 0.0089 0.014
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0077 0.0365 0.2178
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0032 0.0089 0.0216
Treponema pallidum catabolite gene activator (Crp) 0.0032 0.0089 0.271
Echinococcus granulosus cathepsin L cysteine protease 0.0028 0.0068 0.0165
Leishmania major protein kinase A regulatory subunit, putative 0.0032 0.0089 0.0694
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0035 0.0105 0.0828
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0026 0.0185
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0065
Mycobacterium ulcerans oxidoreductase 0.0039 0.0133 0.0205
Loa Loa (eye worm) hypothetical protein 0.0087 0.0429 0.0675
Echinococcus granulosus geminin 0.0573 0.34 0.8256
Echinococcus granulosus multidrug resistance associated protein 7 0.0024 0.0041 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0133 0.0779
Mycobacterium ulcerans regulatory protein 0.0032 0.0089 0.0128
Trypanosoma cruzi target of rapamycin kinase 3 0.0048 0.0188 0.1558
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0089 0.0216
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0039 0.0133 0.0185
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0173 0.0173
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0158 0.0859 0.1497
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0064 0.0282 0.0471
Echinococcus multilocularis multidrug resistance associated protein 1 0.0024 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0091 0.0526
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0076 0.036 0.0873
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0024 0.0041 0.0042
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0032 0.0089 0.0205
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0021 0.0024 0.0059
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0055 0.0231 0.1927
Plasmodium vivax unspecified product 0.0028 0.0068 0.0793
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0158 0.0859 0.7254
Mycobacterium ulcerans hypothetical protein 0.0032 0.0089 0.0128
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0048 0.0188 0.1535
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0173 0.024
Trypanosoma brucei cAMP response protein 1, putative 0.0032 0.0089 0.0694
Brugia malayi CXXC zinc finger family protein 0.0028 0.0066 0.0092
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0064 0.0282 0.0431
Leishmania major oxidoreductase-like protein 0.0039 0.0133 0.1065
Brugia malayi latrophilin 2 splice variant baaae 0.0087 0.0429 0.0597
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0021 0.0024 0.0059
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Echinococcus granulosus ATP binding cassette sub family B 0.0024 0.0041 0.01
Loa Loa (eye worm) multidrug resistance protein 3 0.0077 0.0365 0.0574
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0017 0.0079
Onchocerca volvulus Huntingtin homolog 0.0096 0.0478 0.0701
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0064 0.0282 0.0393
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0004 0.0006
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0668 0.3979 0.7048
Leishmania major acyl carrier protein, putative 0.0064 0.0282 0.2337
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0197 0.1102 0.1894
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0026 0.0033
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0189
Echinococcus multilocularis hyperpolarization activated cyclic 0.069 0.4118 0.4118
Brugia malayi hypothetical protein 0.0025 0.0045 0.0063
Schistosoma mansoni methyltransferase-related 0.0189 0.1053 0.2556
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0026 0.0132
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0136 0.0798
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0089 0.0513
Mycobacterium ulcerans polyketide synthase MbtD 0.0193 0.1076 0.1883
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0096 0.0484 0.0845
Brugia malayi multidrug resistance protein 3 0.0077 0.0365 0.0508
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0232 0.1378
Mycobacterium tuberculosis Conserved protein 0.0189 0.1053 0.1854
Loa Loa (eye worm) hypothetical protein 0.0043 0.0159 0.025
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0039 0.0133 0.0205
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.069 0.4118 0.4118
Giardia lamblia MRP-like ABC transporter 0.0024 0.0041 0.023
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0032 0.0089 0.0124
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0039 0.0133 0.0222
Trypanosoma brucei cAMP binding protein, putative 0.0032 0.0089 0.0694
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0068 0.0095
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0089 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0177 0.1043
Brugia malayi MH1 domain containing protein 0.0021 0.0024 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.009 0.0516
Mycobacterium ulcerans aldehyde dehydrogenase 0.0055 0.0229 0.0377
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0341 0.0828
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0046 0.0173 0.0173
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0086 0.0422 0.1042
Loa Loa (eye worm) hypothetical protein 0.0039 0.0133 0.0209
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0039 0.0133 0.0776
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0173 0.042
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0077 0.0365 0.2178
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0136 0.0212
Leishmania major p-glycoprotein 0.0077 0.0365 0.3038
Mycobacterium tuberculosis Probable thioesterase TesA 0.0524 0.3099 0.5486
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0017 0.0024
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0055 0.0231 0.1904
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0077 0.0365 0.2178
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0017 0.0023
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0232 0.034
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0064 0.0282 0.0393
Mycobacterium ulcerans thioesterase TesA 0.0524 0.3099 0.5478
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0077 0.0365 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0039 0.0133 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0133 0.078
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0668 0.3979 0.7048
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0064 0.0282 0.0444
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0068 0.171
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0039 0.0133 0.0322
Toxoplasma gondii type I fatty acid synthase, putative 0.0448 0.2632 0.6608
Leishmania major ABC-thiol transporter 0.0024 0.0041 0.0285
Leishmania major cathepsin L-like protease 0.0055 0.0232 0.1911
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0064 0.0282 0.0282
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0026 0.0157
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.069 0.4118 1
Leishmania major cathepsin L-like protease 0.0055 0.0232 0.1911
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0089 0.0513
Echinococcus multilocularis multidrug resistance protein 1 0.0054 0.0222 0.0222
Giardia lamblia Multidrug resistance-associated protein 1 0.0023 0.0036 0.018
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0026 0.0063
Trypanosoma cruzi Flagellar Member 6 0.0032 0.0089 0.072
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0514 0.3039 0.538
Echinococcus granulosus GPCR family 2 0.004 0.0142 0.0344
Onchocerca volvulus 0.0032 0.0089 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0108 0.017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0026 0.0185
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.1192 0.7185 1
Leishmania major cyclic nucleotide-binding protein-like protein 0.0032 0.0089 0.0694
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0506 0.2989 0.5262
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0232 0.0564
Loa Loa (eye worm) hypothetical protein 0.0086 0.0423 0.0665
Echinococcus granulosus cysteine protease 0.0028 0.0068 0.0165
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.004 0.0137 0.0332
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0077 0.0365 0.2178
Echinococcus granulosus dna polymerase kappa 0.0022 0.0026 0.0063
Brugia malayi acetyltransferase, GNAT family protein 0.0293 0.1688 0.235
Entamoeba histolytica multidrug resistance protein, putative 0.0024 0.0041 0.0987
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0189
Plasmodium vivax ABC transporter B family member 4, putative 0.0024 0.0041 0.0479
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0077 0.0365 0.2178
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0021 0.0024 0.0024
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0096 0.0484 0.0845
Schistosoma mansoni multidrug resistance protein 0.0024 0.0041 0.01
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0154 0.0834 0.1466
Brugia malayi Papain family cysteine protease containing protein 0.0055 0.0232 0.0323
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0055 0.0231 0.1904
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0136 0.0798
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0039 0.0133 0.3441
Entamoeba histolytica P-glycoprotein 5, putative 0.0077 0.0365 0.9655
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.009 0.0516
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0055 0.0229 0.0557
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0033 0.0094 0.0154
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0136 0.0136
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0028 0.0068 0.0165
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0032 0.0089 0.0145
Leishmania major cathepsin L-like protease 0.0055 0.0232 0.1911
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.002 0.0019 0.0093
Onchocerca volvulus 0.0064 0.0282 0.0413
Plasmodium falciparum multidrug resistance protein 1 0.0077 0.0365 0.4244
Schistosoma mansoni cpg binding protein 0.0028 0.0066 0.0161
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0136 0.0331
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0077 0.0365 0.0365
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0026 0.0036
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.004 0.0142 0.0142
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0077 0.0365 0.0886
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0049 0.0191 0.0191
Mycobacterium tuberculosis Polyketide synthase Pks13 0.094 0.5643 1
Entamoeba histolytica hypothetical protein 0.0073 0.0341 0.9019
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0026 0.0041
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0032 0.0089 0.0216
Brugia malayi N-terminal motif family protein 0.0236 0.1337 0.1861
Brugia malayi cathepsin L-like precursor 0.0037 0.012 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0211 0.1183 1
Leishmania major regulatory subunit of protein kinase a-like protein 0.0032 0.0089 0.0694
Echinococcus multilocularis NADH dehydrogenase 0.0064 0.0282 0.0282
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.004 0.0142 0.0344
Brugia malayi Cathepsin L-like precursor 0.0037 0.012 0.0167
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0046 0.0173 0.042
Loa Loa (eye worm) transcription factor SMAD2 0.0313 0.1808 0.2844
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0232 0.0232
Entamoeba histolytica hypothetical protein 0.0035 0.0105 0.2698
Echinococcus multilocularis cysteine protease 0.0055 0.0232 0.0232
Brugia malayi Cathepsin L-like cysteine proteinase 0.0037 0.012 0.0167
Brugia malayi ABC transporter family protein 0.0077 0.0365 0.0508
Echinococcus multilocularis multidrug resistance protein 1 0.0077 0.0365 0.0365
Schistosoma mansoni inositol monophosphatase 0.004 0.0136 0.0331
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0024 0.0041 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0133 0.0779
Loa Loa (eye worm) ABC transporter 0.0024 0.0041 0.0065
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0275 0.1575 0.3825
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0024 0.0041 0.0285
Schistosoma mansoni hypothetical protein 0.004 0.0142 0.0344
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0055 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0071
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0009
Plasmodium vivax hypothetical protein, conserved 0.009 0.0445 0.518
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0046 0.0173 0.042
Brugia malayi cytoplasmic intermediate filament protein 0.0024 0.0039 0.0054
Echinococcus multilocularis muscleblind protein 1 0.0295 0.17 0.17
Mycobacterium tuberculosis Hypothetical protein 0.0189 0.1053 0.1854
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0064 0.0282 0.0488
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0024 0.0041 0.0042
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0086 0.0422 0.4905
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0064 0.0282 0.0471
Loa Loa (eye worm) hypothetical protein 0.0482 0.2841 0.447
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0041 0.0041
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0028 0.0068 0.0165
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0032 0.0089 0.072
Schistosoma mansoni lipoxygenase 0.0049 0.0191 0.0464
Entamoeba histolytica cysteine proteinase 1, putative 0.0028 0.0068 0.171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Onchocerca volvulus 0.0028 0.0066 0.0097
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0035 0.0105 0.0854
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0024 0.0041 0.0285
Plasmodium falciparum ABC transporter B family member 4, putative 0.0024 0.0041 0.0479
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0077 0.0365 0.2178
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0024 0.0041 0.0042
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0168 0.0234
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0035 0.0105 0.0255
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0077 0.0365 0.0899
Echinococcus multilocularis cpg binding protein 0.003 0.0076 0.0076
Brugia malayi Cathepsin L-like precursor 0.0037 0.012 0.0167
Leishmania major d-xylulose reductase, putative 0.0039 0.0133 0.1065
Onchocerca volvulus 0.0039 0.0133 0.0194
Giardia lamblia Histone acetyltransferase GCN5 0.0079 0.0378 0.348
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0044 0.0164 0.0258
Mycobacterium ulcerans hypothetical protein 0.0032 0.0089 0.0128
Entamoeba histolytica cysteine protease, putative 0.0055 0.0232 0.6105
Entamoeba histolytica cysteine protease, putative 0.0028 0.0068 0.171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0232 0.1378
Giardia lamblia Multidrug resistance-associated protein 1 0.0024 0.0041 0.023
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0173 0.042
Brugia malayi ABC transporter transmembrane region family protein 0.0024 0.0041 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0231 0.1373
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0026 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0177 0.1043
Brugia malayi Muscleblind-like protein 0.0295 0.17 0.2366
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0008 0.0008
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0158 0.0859 0.0859
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0041 0.0084
Echinococcus multilocularis multidrug resistance protein 1 0.0077 0.0365 0.0365
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0039 0.0133 0.0205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0133 0.0209
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0158 0.0859 0.7254
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0006 0.0009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0077 0.0365 0.2178
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0009
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0055 0.0232 0.2702
Trypanosoma cruzi cAMP binding protein, putative 0.0032 0.0089 0.072
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0232 0.0232
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0039 0.0133 0.109
Leishmania major phosphatidylinositol kinase related protein, putative 0.0023 0.0032 0.0209
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0032 0.0089 0.0216
Brugia malayi Cathepsin L-like precursor 0.0055 0.0232 0.0323
Giardia lamblia Multidrug resistance-associated protein 1 0.0024 0.0041 0.023
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0416 0.2437 0.4278

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 21.87 uM PubChem BioAssay. Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1). (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 39.832 uM PubChem BioAssay. Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.1093 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 42.5615 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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