Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0065 | 0.0748 | 0.2405 |
Schistosoma mansoni | coup transcription factor | 0.0023 | 0.0172 | 0.0258 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.045 | 0.1215 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0023 | 0.0172 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0065 | 0.0748 | 0.2405 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0023 | 0.0172 | 0.0258 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0066 | 0.0761 | 0.2454 |
Loa Loa (eye worm) | DR-78 | 0.0011 | 0.0007 | 0.0005 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0023 | 0.0172 | 0.0172 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.01 | 0.1229 | 0.1692 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Echinococcus multilocularis | GPCR, family 2 | 0.01 | 0.1229 | 0.1692 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0023 | 0.0172 | 0.0235 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1149 | 0.1787 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0051 | 0.0551 | 0.0757 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0023 | 0.0172 | 0.0235 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0743 | 1 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0051 | 0.0551 | 0.085 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0023 | 0.0172 | 0.0172 |
Schistosoma mansoni | thyroid hormone receptor | 0.0166 | 0.212 | 0.3305 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0198 | 0.2559 | 0.2557 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0043 | 0.045 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.2735 | 0.2734 |
Onchocerca volvulus | 0.0019 | 0.0119 | 0.3578 | |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0065 | 0.0748 | 0.2405 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0847 | 0.2782 |
Onchocerca volvulus | 0.0019 | 0.0119 | 0.3578 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Plasmodium vivax | ornithine aminotransferase, putative | 0.0023 | 0.0171 | 0.0202 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0023 | 0.0172 | 0.0235 |
Brugia malayi | 4-aminobutyrate aminotransferase, mitochondrial precursor | 0.0023 | 0.0171 | 0.0171 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0119 | 0.0119 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0065 | 0.0748 | 0.1302 |
Loa Loa (eye worm) | fibroinase | 0.0019 | 0.0119 | 0.0117 |
Mycobacterium tuberculosis | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 0.0161 | 0.2053 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0012 | 0.0025 | 0.0028 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0165 | 0.0225 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0023 | 0.0172 | 0.0235 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0023 | 0.0169 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0242 | 0.024 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0023 | 0.0169 | 0.023 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0023 | 0.0172 | 0.0172 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.073 | 0.2335 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.0319 | 0.0319 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0019 | 0.0119 | 0.0117 |
Onchocerca volvulus | 0.0034 | 0.0319 | 1 | |
Echinococcus granulosus | Aminotransferase class III | 0.0023 | 0.0171 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0025 | 0.0023 |
Mycobacterium tuberculosis | Probable aminotransferase | 0.0161 | 0.2053 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0023 | 0.0172 | 0.0172 |
Echinococcus multilocularis | tar DNA binding protein | 0.0198 | 0.2559 | 0.3526 |
Schistosoma mansoni | nuclear hormone receptor | 0.0023 | 0.0172 | 0.0258 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0043 | 0.045 | 0.1215 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0025 | 0.0028 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0023 | 0.0172 | 0.0235 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.045 | 0.0618 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0119 | 0.0161 |
Brugia malayi | nuclear receptor RXR | 0.0012 | 0.0025 | 0.0025 |
Onchocerca volvulus | 0.0019 | 0.0119 | 0.3578 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0211 | 0.2735 | 1 |
Brugia malayi | hypothetical protein | 0.0136 | 0.1716 | 0.1716 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0025 | 0.0023 |
Trichomonas vaginalis | acetylornithine aminotransferase, putative | 0.0161 | 0.2053 | 0.5882 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0119 | 0.2052 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0023 | 0.0172 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0211 | 0.2735 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0065 | 0.0748 | 0.1302 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0023 | 0.0172 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Trichomonas vaginalis | glutaminase, putative | 0.0264 | 0.3466 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0023 | 0.0172 | 0.0258 |
Echinococcus granulosus | RUN | 0.0022 | 0.0165 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0033 | 0.0031 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0063 | 0.0714 | 0.0982 |
Brugia malayi | MH1 domain containing protein | 0.0051 | 0.0551 | 0.0551 |
Brugia malayi | Smad1 | 0.0051 | 0.0551 | 0.0551 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0023 | 0.0172 | 0.0171 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1229 | 0.1911 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0023 | 0.0172 | 0.0172 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Echinococcus granulosus | ornithine aminotransferase | 0.0023 | 0.0171 | 0.0234 |
Schistosoma mansoni | lipoxygenase | 0.0022 | 0.0165 | 0.0246 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0211 | 0.2735 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0051 | 0.0551 | 0.0757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Brugia malayi | tailless protein | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0119 | 0.0161 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0065 | 0.0748 | 0.2405 |
Loa Loa (eye worm) | RNA binding protein | 0.0198 | 0.2559 | 0.2557 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0119 | 0.0174 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0023 | 0.0169 | 0.5175 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0013 | 0.0033 | 0.0033 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.0165 | 0.0225 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0023 | 0.0172 | 0.0171 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0023 | 0.0172 | 0.0258 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0023 | 0.0171 | 0.0234 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0011 | 0.0007 | 0.0007 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0065 | 0.0748 | 0.2405 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1229 | 0.1911 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.0746 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.0319 | 0.0317 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0023 | 0.0172 | 0.0258 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0119 | 0.0161 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0023 | 0.0169 | 0.023 |
Onchocerca volvulus | 0.0023 | 0.0172 | 0.5299 | |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0033 | 0.0033 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0011 | 0.0007 | 0.0005 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0023 | 0.0172 | 0.0235 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0119 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.2818 | 0.2817 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0165 | 0.0163 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0023 | 0.0172 | 0.0235 |
Schistosoma mansoni | smad1 5 8 and | 0.0051 | 0.0551 | 0.085 |
Brugia malayi | Inositol-1 | 0.0043 | 0.045 | 0.045 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1229 | 0.1911 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0065 | 0.0748 | 0.1029 |
Plasmodium falciparum | ornithine aminotransferase | 0.0023 | 0.0171 | 0.0202 |
Schistosoma mansoni | smad1 5 8 and | 0.0051 | 0.0551 | 0.085 |
Onchocerca volvulus | 0.0022 | 0.0165 | 0.5053 | |
Schistosoma mansoni | smad1 5 8 and | 0.0051 | 0.0551 | 0.085 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0011 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.0033 | 0.0041 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0019 | 0.0119 | 0.0117 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0039 | 0.0388 | 0.1153 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0023 | 0.0171 | 0.0234 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0025 | 0.0025 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0165 | 0.0165 |
Schistosoma mansoni | smad | 0.0023 | 0.0169 | 0.0252 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0119 | 0.0161 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.01 | 0.1229 | 0.1692 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0023 | 0.0172 | 0.0171 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0023 | 0.0172 | 0.0235 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1229 | 0.1911 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.0834 | 0.1293 |
Brugia malayi | ecdysteroid receptor | 0.0023 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | cysteine protease | 0.0019 | 0.0119 | 0.0117 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0022 | 0.0165 | 0.0176 |
Echinococcus granulosus | smad | 0.0051 | 0.0551 | 0.0757 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.1029 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0025 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0023 | 0.0172 | 0.0171 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0542 | 0.7254 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0542 | 0.7254 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0023 | 0.0172 | 0.0172 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0033 | 0.0033 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0051 | 0.0551 | 0.0549 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.045 | 0.0693 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.045 | 0.1267 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0023 | 0.0172 | 0.0172 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0023 | 0.0169 | 0.0169 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0023 | 0.0172 | 0.0172 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0319 | 0.0488 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0025 | 0.0023 |
Mycobacterium ulcerans | adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 0.0161 | 0.2053 | 0.5709 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.1807 | 0.2816 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0023 | 0.0172 | 0.0235 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Schistosoma mansoni | glutaminase | 0.0264 | 0.3466 | 0.5411 |
Echinococcus granulosus | GPCR family 2 | 0.01 | 0.1229 | 0.1692 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0023 | 0.0172 | 0.0235 |
Toxoplasma gondii | ornithine aminotransferase, mitochondrial precursor, putative | 0.0023 | 0.0171 | 0.0202 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.045 | 0.1267 |
Brugia malayi | MH1 domain containing protein | 0.0028 | 0.0242 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0119 | 0.0117 |
Brugia malayi | hypothetical protein | 0.0211 | 0.2735 | 0.2735 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0011 | 0.0007 | 0.0005 |
Brugia malayi | nuclear receptor NHR-88 | 0.0023 | 0.0172 | 0.0172 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.045 | 0.0693 |
Schistosoma mansoni | Smad4 | 0.0023 | 0.0169 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0051 | 0.0551 | 0.0549 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0063 | 0.0714 | 0.0982 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.045 | 0.1267 |
Echinococcus granulosus | tar DNA binding protein | 0.0198 | 0.2559 | 0.3526 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.01 | 0.1229 | 0.1692 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0007 | 0.0007 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0165 | 0.0246 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0011 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0165 | 0.0163 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.2559 | 0.3991 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0022 | 0.0165 | 0.0225 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0025 | 0.0025 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0143 | 0.1807 | 0.2489 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0023 | 0.0172 | 0.0172 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Mycobacterium leprae | PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA | 0.0161 | 0.2053 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0039 | 0.0388 | 0.1153 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.045 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0012 | 0.0025 | 0.0032 |
Onchocerca volvulus | 0.0019 | 0.0119 | 0.3578 | |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.2405 |
Brugia malayi | Isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.0748 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0119 | 0.3578 |
Schistosoma mansoni | loxhd1 | 0.0022 | 0.0165 | 0.0246 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.1029 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0072 | 0.0847 | 0.2782 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0023 | 0.0169 | 0.023 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Loa Loa (eye worm) | glutaminase 2 | 0.0264 | 0.3466 | 0.3465 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0022 | 0.0165 | 0.0176 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0345 | 0.0473 |
Schistosoma mansoni | polycystin 1-related | 0.0022 | 0.0165 | 0.0246 |
Brugia malayi | glutaminase DH11.1 | 0.0264 | 0.3466 | 0.3466 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0847 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0033 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0023 | 0.0172 | 0.0172 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0051 | 0.0551 | 0.0757 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | RUN | 0.0022 | 0.0165 | 0.0225 |
Brugia malayi | MH1 domain containing protein | 0.0028 | 0.0242 | 0.0242 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.1159 |
Schistosoma mansoni | smad | 0.0051 | 0.0551 | 0.085 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0023 | 0.0172 | 0.0172 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0847 | 0.2782 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0022 | 0.0165 | 0.0225 |
Schistosoma mansoni | thyroid hormone receptor | 0.0166 | 0.212 | 0.3305 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0023 | 0.0172 | 0.0172 |
Brugia malayi | steroid hormone receptor | 0.0023 | 0.0172 | 0.0172 |
Brugia malayi | MH1 domain containing protein | 0.0051 | 0.0551 | 0.0551 |
Brugia malayi | conserved hypotetical protein | 0.0011 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0023 | 0.0172 | 0.0171 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0165 | 0.0225 |
Onchocerca volvulus | 0.0022 | 0.0165 | 0.5053 | |
Brugia malayi | RNA binding protein | 0.0198 | 0.2559 | 0.2559 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.045 | 0.0618 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0119 | 0.3578 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0023 | 0.0172 | 0.0171 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0051 | 0.0551 | 0.0757 |
Schistosoma mansoni | hypothetical protein | 0.0479 | 0.64 | 1 |
Loa Loa (eye worm) | nuclear factor I | 0.0028 | 0.0242 | 0.024 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.0165 | 0.0246 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0143 | 0.1807 | 0.2489 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0119 | 0.0161 |
Onchocerca volvulus | 0.0019 | 0.0119 | 0.3578 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Brugia malayi | MH2 domain containing protein | 0.0051 | 0.0551 | 0.0551 |
Leishmania major | hypothetical protein, conserved | 0.0211 | 0.2735 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0023 | 0.0169 | 0.0167 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0345 | 0.0529 |
Schistosoma mansoni | Smad4 | 0.0051 | 0.0551 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Brugia malayi | cathepsin L-like precursor | 0.0013 | 0.0033 | 0.0033 |
Loa Loa (eye worm) | TAR-binding protein | 0.0198 | 0.2559 | 0.2557 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0119 | 0.2052 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0033 | 0.0031 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0057 | 0.0635 | 0.1974 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0023 | 0.0172 | 0.0172 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.045 | 0.1267 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0011 | 0.0007 | 0.0005 |
Echinococcus multilocularis | Smad4 | 0.0051 | 0.0551 | 0.0757 |
Loa Loa (eye worm) | ctsf protein | 0.0019 | 0.0119 | 0.0117 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0072 | 0.0847 | 0.2782 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0119 | 0.0119 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0023 | 0.0172 | 0.0235 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0011 | 0.0007 | 0.0007 |
Echinococcus granulosus | cathepsin l1 | 0.0013 | 0.0033 | 0.0043 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0119 | 0.0119 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0065 | 0.0748 | 0.3064 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0011 | 0.0007 | 0.0007 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.2559 | 0.3991 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0165 | 0.0165 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.01 | 0.1229 | 0.1227 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Brugia malayi | nuclear receptor NHR-67 | 0.0011 | 0.0007 | 0.0007 |
Onchocerca volvulus | 0.0013 | 0.0033 | 0.0831 | |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0165 | 0.0246 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0012 | 0.0025 | 0.0032 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.1029 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0012 | 0.0025 | 0.0023 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0023 | 0.0172 | 0.0235 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0023 | 0.0172 | 0.5299 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0743 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0023 | 0.0172 | 0.5299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.2559 | 0.3991 |
Brugia malayi | MH2 domain containing protein | 0.0051 | 0.0551 | 0.0551 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0023 | 0.0172 | 0.0235 |
Brugia malayi | Latrophilin receptor protein 2 | 0.01 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0011 | 0.0007 | 0.0007 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0211 | 0.2735 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0211 | 0.2735 | 1 |
Echinococcus granulosus | Smad4 | 0.0051 | 0.0551 | 0.0757 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0345 | 0.0473 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0011 | 0.0007 | 0.0007 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0072 | 0.0847 | 0.2782 |
Chlamydia trachomatis | glutamate-1-semialdehyde-2,1-aminomutase | 0.0023 | 0.0171 | 0.5 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.1029 |
Echinococcus granulosus | FTZ F1 alpha | 0.0023 | 0.0172 | 0.0235 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.045 | 0.0846 |
Entamoeba histolytica | cysteine protease, putative | 0.0019 | 0.0119 | 0.2052 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0023 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0025 | 0.0023 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0023 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | doublecortin family protein | 0.0022 | 0.0165 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0217 | 0.2818 | 0.2818 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.2559 | 0.3991 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0023 | 0.0172 | 0.0258 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0072 | 0.0847 | 0.2782 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.1029 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | nuclear receptor RXR | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | MH2 domain containing protein | 0.0023 | 0.0169 | 0.0169 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0317 | 0.4187 | 0.4187 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0007 | 0.0007 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0023 | 0.0172 | 0.5299 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.045 | 0.1215 |
Onchocerca volvulus | 0.0019 | 0.0119 | 0.3578 | |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0023 | 0.0172 | 0.0235 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.2405 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0023 | 0.0172 | 0.0172 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0095 | 0.1149 | 0.1583 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0023 | 0.0172 | 0.0171 |
Echinococcus multilocularis | smad | 0.0051 | 0.0551 | 0.0757 |
Brugia malayi | ecdysone receptor | 0.0011 | 0.0007 | 0.0007 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0019 | 0.0119 | 0.0161 |
Schistosoma mansoni | hypothetical protein | 0.0217 | 0.2818 | 0.4397 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0005 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0023 | 0.0172 | 0.0235 |
Echinococcus granulosus | dnaJ subfamily B | 0.0479 | 0.64 | 0.8823 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0479 | 0.64 | 0.8823 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0019 | 0.0119 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0119 | 0.0174 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0023 | 0.0169 | 0.0167 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0095 | 0.1149 | 0.1583 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.2559 | 0.3991 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.045 | 0.0449 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0345 | 0.0529 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0023 | 0.0172 | 0.0258 |
Schistosoma mansoni | Smad4 | 0.0023 | 0.0169 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0169 | 0.0167 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0317 | 0.4187 | 0.4186 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0025 | 0.0025 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Onchocerca volvulus | 0.0019 | 0.0119 | 0.3578 | |
Echinococcus multilocularis | Aminotransferase class III | 0.0023 | 0.0171 | 0.0234 |
Onchocerca volvulus | Cathepsin F homolog | 0.0019 | 0.0119 | 0.3578 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0119 | 0.0119 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0211 | 0.2735 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0065 | 0.0748 | 0.0748 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0166 | 0.212 | 0.2921 |
Schistosoma mansoni | ornithine--oxo-acid transaminase | 0.0023 | 0.0171 | 0.0257 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.01 | 0.1229 | 0.1692 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1229 | 0.1227 |
Brugia malayi | Doublecortin family protein | 0.0022 | 0.0165 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0172 | 0.0171 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0119 | 0.0119 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0119 | 0.0161 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0023 | 0.0172 | 0.0258 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0198 | 0.2559 | 0.2559 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Loa Loa (eye worm) | Smad1 | 0.0051 | 0.0551 | 0.0549 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.01 | 0.1229 | 0.1229 |
Mycobacterium ulcerans | glutaminase | 0.0264 | 0.3466 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0317 | 0.4187 | 0.4186 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.0165 | 0.0225 |
Loa Loa (eye worm) | glutaminase | 0.0264 | 0.3466 | 0.3465 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0317 | 0.4187 | 0.4187 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0542 | 0.7254 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0211 | 0.2735 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.0847 | 0.1734 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0023 | 0.0172 | 0.0258 |
Echinococcus granulosus | neuropeptide s receptor | 0.0542 | 0.7254 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0011 | 0.0007 | 0.0007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Schistosoma mansoni | lipoxygenase | 0.0063 | 0.0714 | 0.1105 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Mycobacterium ulcerans | hypothetical protein | 0.0161 | 0.2053 | 0.5709 |
Brugia malayi | TAR-binding protein | 0.0198 | 0.2559 | 0.2559 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0119 | 0.0249 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0023 | 0.0172 | 0.0172 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 32.6427 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.