Detailed information for compound 154566

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 379.538 | Formula: C15H29N3O4S2
  • H donors: 4 H acceptors: 4 LogP: -1.83 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSCC[C@@H](C(=O)O)NC(=O)CCCCCCNC(=O)[C@H](CS)N
  • InChi: 1S/C15H29N3O4S2/c1-24-9-7-12(15(21)22)18-13(19)6-4-2-3-5-8-17-14(20)11(16)10-23/h11-12,23H,2-10,16H2,1H3,(H,17,20)(H,18,19)(H,21,22)/t11-,12-/m0/s1
  • InChiKey: ZMTILBPFJCBPIT-RYUDHWBXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens farnesyltransferase, CAAX box, alpha Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Babesia bovis protein prenyltransferase alpha subunit repeat domain containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein Get druggable targets OG5_128459 All targets in OG5_128459
Toxoplasma gondii hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Schistosoma mansoni protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus granulosus protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium knowlesi protein farnesyltransferase subunit alpha, putative Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Schistosoma japonicum ko:K05954 farnesyltransferase, CAAX box, alpha [EC:2.5.1.58 2.5.1.59], putative Get druggable targets OG5_128459 All targets in OG5_128459
Cryptosporidium parvum farnesyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium berghei protein farnesyltransferase subunit alpha, putative Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium falciparum protein farnesyltransferase subunit alpha Get druggable targets OG5_128459 All targets in OG5_128459
Cryptosporidium hominis farnesyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Plasmodium vivax prenyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Echinococcus multilocularis protein farnesyltransferase alpha subunit Get druggable targets OG5_128459 All targets in OG5_128459
Theileria parva hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Giardia lamblia Rab geranylgeranyltransferase Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans alpha subunit shared by C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) and farnesyltransferase (Ram2p+Ram1p) Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
Neospora caninum hypothetical protein Get druggable targets OG5_128459 All targets in OG5_128459
Candida albicans alpha subunit shared by C terminal CaaX Geranylgeranyltransferase I (Ram2p+Cdc43p) and farnesyltransferase (Ram2p+Ram1p) Get druggable targets OG5_128459 All targets in OG5_128459
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative Get druggable targets OG5_128459 All targets in OG5_128459
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0054 0.0456
Echinococcus granulosus neuropeptide receptor 0.0052 0.0152 0.0826
Brugia malayi neuropeptide F receptor 0.0052 0.0152 0.1447
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0014 0.0066
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0231 0.3574
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0152 0.0826
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0011 0.0011 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0231 0.3648
Schistosoma mansoni hypothetical protein 0.0027 0.0064 0.0306
Brugia malayi intermediate filament protein 0.0059 0.0176 0.1688
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.005 0.0144 0.1198
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0027 0.0064 0.0056
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0011 0.0051
Loa Loa (eye worm) hypothetical protein 0.0076 0.0231 0.1968
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0011 0.0022
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0024 0.0054 0.0045
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0027 0.0064 0.0056
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0221 0.3503
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0011 0.0051
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0166 0.4272
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0026 0.0096
Trypanosoma cruzi cytochrome P450, putative 0.0093 0.0288 0.7592
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0011 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0231 0.3648
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.001 0.0009 0.0251
Loa Loa (eye worm) hypothetical protein 0.0076 0.0231 0.1968
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0027 0.0064 0.0056
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0079 0.0243 0.1328
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0011 0.0022
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0051 0.0269
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0231 0.1258
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0014 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0144 0.3665
Brugia malayi Melatonin receptor type 1A 0.0052 0.0152 0.1447
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus multilocularis lamin 0.0059 0.0176 0.0957
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0054 0.1005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0054 0.1005
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0083 0.2329
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0152 0.0826
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0152 0.0826
Brugia malayi sodium-independent organic anion transporter family protein 0.0119 0.0377 0.3725
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0079 0.0243 0.1328
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0152 0.1447
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0152 0.0826
Mycobacterium tuberculosis Conserved protein 0.0076 0.0231 0.0222
Treponema pallidum NADH oxidase 0.0024 0.0054 0.4069
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0011 0.0019
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0027 0.0064 0.0056
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0193 0.0629 0.3449
Echinococcus granulosus sex peptide receptor 0.0052 0.0152 0.0826
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0014 0.0191
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0039
Schistosoma mansoni amine GPCR 0.0052 0.0152 0.0789
Echinococcus multilocularis 0.0027 0.0064 0.0345
Onchocerca volvulus 0.0011 0.0011 0.0058
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0243 0.6852
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0079 0.0243 0.6771
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0052 0.0152 0.0826
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0027 0.0064 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0027 0.0064 0.0056
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0026 0.0136
Toxoplasma gondii ABC1 family protein 0.0076 0.0231 0.4922
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0014 0.0066
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0054 0.0288
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0152 0.0826
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0152 0.0826
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0026 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0079 0.0243 0.385
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.005 0.0144 0.3665
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0011 0.0012
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0025 0.0126
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0119 0.0377 0.3268
Brugia malayi putative neuropeptide receptor 0.0052 0.0152 0.1447
Loa Loa (eye worm) hypothetical protein 0.0119 0.0377 0.3268
Echinococcus granulosus hypothetical protein 0.0052 0.0152 0.0826
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0166 0.2621
Schistosoma mansoni organic anion transporter 0.0119 0.0377 0.2031
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0093 0.0288 0.028
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0014 0.0191
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0119 0.0377 0.3268
Echinococcus granulosus neuropeptide s receptor 0.0052 0.0152 0.0826
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0054 0.0727
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0193 0.0629 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0014 0.0191
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0011 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0249 0.5333
Plasmodium falciparum thioredoxin reductase 0.0068 0.0205 0.317
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0011 0.0051
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0026 0.0393
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Echinococcus multilocularis thioredoxin glutathione reductase 0.0068 0.0205 0.112
Brugia malayi sodium-independent organic anion transporter family protein 0.0119 0.0377 0.3725
Schistosoma mansoni netrin receptor unc5 0.0015 0.0025 0.0087
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0026 0.0136
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0043 0.012 0.0614
Brugia malayi sodium-independent organic anion transporter family protein 0.0119 0.0377 0.3725
Brugia malayi Cytochrome P450 family protein 0.0093 0.0288 0.2828
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0231 0.1968
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0144 0.405
Brugia malayi prostaglandin transporter 0.0119 0.0377 0.3725
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0166 0.2535
Trypanosoma brucei protein kinase A regulatory subunit 0.001 0.0009 0.0251
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0027 0.0064 0.1603
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0043 0.012 0.0111
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0789
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0011 0.0019
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0152 0.127
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0152 0.1447
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0011 0.0012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0152 0.3885
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0014 0.0191
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0043 0.012 1
Echinococcus multilocularis patatin phospholipase domain containing protein 0.001 0.0009 0.004
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.001 0.0009 0.0115
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0012 0.0014 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0011 0.0051
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0024 0.0054 0.0045
Schistosoma mansoni multidrug resistance protein 0.0012 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0076 0.0231 0.1968
Echinococcus granulosus lamin 0.0059 0.0176 0.0957
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0152 0.0789
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0152 0.0789
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Brugia malayi Uncoordinated protein 44 0.0015 0.0025 0.0159
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0014 0.0191
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0012 0.0014 0.0138
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0054 0.1308
Echinococcus granulosus orexin receptor type 2 0.0052 0.0152 0.0826
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0026 0.0096
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0011 0.0011 0.0039
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0789
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0042
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0025 0.0428
Loa Loa (eye worm) hypothetical protein 0.0119 0.0377 0.3268
Treponema pallidum cysteinyl-tRNA synthetase 0.0043 0.012 1
Onchocerca volvulus 0.0052 0.0152 0.3885
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0052 0.0152 0.0826
Echinococcus multilocularis transcription factor btf3 0.0112 0.0355 0.1942
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0027 0.0064 0.0056
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0027 0.0064 0.0056
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0152 0.0789
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0152 0.127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0011 0.0051
Brugia malayi Dopamine receptor 0.0052 0.0152 0.1447
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0027 0.0064 0.0056
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0152 0.0826
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.005 0.0144 0.2114
Loa Loa (eye worm) hypothetical protein 0.0058 0.0172 0.1448
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0014 0.0066
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0011 0.0051
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0025 0.0126
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0014 0.0191
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0119 0.0377 0.2063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0231 0.3648
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0152 0.0826
Mycobacterium tuberculosis Conserved protein 0.0076 0.0231 0.0222
Loa Loa (eye worm) glutathione reductase 0.0068 0.0205 0.1746
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0024 0.0054 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0231 0.6023
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0054 0.1308
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0011 0.0012
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0152 0.0789
Schistosoma mansoni multidrug resistance protein 0.0012 0.0014 0.0026
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0249 0.5333
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0043 0.012 0.0988
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.0009 0.004
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0152 0.0826
Schistosoma mansoni neuropeptide receptor 0.0052 0.0152 0.0789
Echinococcus granulosus neuropeptide receptor 0.0052 0.0152 0.0826
Echinococcus multilocularis expressed conserved protein 0.0011 0.0011 0.0049
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0026 0.0176
Trichomonas vaginalis abcb9, putative 0.0012 0.0014 0.0191
Chlamydia trachomatis cysteine--tRNA ligase 0.0043 0.012 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni amine GPCR 0.0052 0.0152 0.0789
Brugia malayi G-protein coupled receptor 0.0052 0.0152 0.1447
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0014 0.0191
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.2951 1 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0027 0.0064 0.0056
Onchocerca volvulus 0.0052 0.0152 0.3885
Brugia malayi beta-lactamase family protein 0.0076 0.0231 0.2244
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Onchocerca volvulus 0.0059 0.0176 0.4532
Onchocerca volvulus 0.0119 0.0377 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0166 0.4272
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0027 0.0064 0.0056
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0083 0.2329
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0231 0.1223
Schistosoma mansoni multidrug resistance protein 0.0012 0.0014 0.0026
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0176 0.1481
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0152 0.0789
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni neuropeptide receptor 0.0052 0.0152 0.0789
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.005 0.0144 0.0781
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0027 0.0064 0.0056
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0011 0.0058
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0025 0.0087
Schistosoma mansoni cytochrome P450 0.0027 0.0064 0.0306
Leishmania major cytochrome p450-like protein 0.0027 0.0064 0.1603
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.0009 0.004
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0043 0.012 0.173
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0064 0.0492
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0249 0.5333
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0017 0.0033 0.0243
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0054 0.152
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.005 0.0144 0.2265
Brugia malayi cytochrome P450 0.0027 0.0064 0.0561
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0011 0.0019
Echinococcus granulosus ubiquitin specific protease 41 0.0079 0.0243 0.1328
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0027 0.0064 0.0056
Plasmodium falciparum glutathione reductase 0.0024 0.0054 0.073
Brugia malayi hypothetical protein 0.0119 0.0377 0.3725
Loa Loa (eye worm) hypothetical protein 0.0015 0.0026 0.0155
Schistosoma mansoni hypothetical protein 0.0342 0.1135 0.6215
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0054 0.073
Entamoeba histolytica transcription factor BTF3, putative 0.0112 0.0355 0.5546
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0014 0.0066
Mycobacterium leprae Conserved hypothetical protein 0.0027 0.0064 0.0056
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0231 0.3648
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0193 0.0629 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0054 0.0288
Loa Loa (eye worm) hypothetical protein 0.0119 0.0377 0.3268
Trypanosoma cruzi transcription factor btf3, putative 0.0112 0.0355 0.9405
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0027 0.0064 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0011 0.0019
Toxoplasma gondii cytochrome p450 superfamily protein 0.0027 0.0064 0.1232
Brugia malayi Serotonin receptor 0.0052 0.0152 0.1447
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0012 0.0014 0.043
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0071 0.0383
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0027 0.0064 0.0056
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0026 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0243 0.385
Brugia malayi Cytochrome P450 family protein 0.0027 0.0064 0.0561
Plasmodium falciparum importin beta, putative 0.0032 0.0083 0.119
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0011 0.0051
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0054 0.1526
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0166 0.0904
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0152 0.0826
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0012 0.0014 0.0191
Brugia malayi MAP kinase sur-1 0.0057 0.0166 0.1592
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0152 0.0826
Trypanosoma cruzi trypanothione reductase, putative 0.0068 0.0205 0.5342
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0152 0.0789
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.1308
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0026 0.0096
Leishmania major cytochrome p450-like protein 0.0093 0.0288 0.8073
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.1308
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0011 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0011 0.001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0152 0.0826
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0027 0.0064 0.1507
Brugia malayi beta-lactamase 0.0076 0.0231 0.2244
Schistosoma mansoni transcription factor btf3 0.0112 0.0355 0.191
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0166 0.4543
Onchocerca volvulus 0.0052 0.0152 0.3885
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0152 0.0789
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0152 0.0826
Schistosoma mansoni hypothetical protein 0.0015 0.0025 0.0087
Onchocerca volvulus 0.0052 0.0152 0.3885
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0011 0.0012
Brugia malayi sulfakinin receptor protein 0.0052 0.0152 0.1447
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0011 0.0051
Loa Loa (eye worm) hypothetical protein 0.0066 0.0198 0.1678
Plasmodium vivax multidrug resistance protein 1, putative 0.0012 0.0014 0.0077
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0054 0.1001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0176 0.1481
Brugia malayi Death domain containing protein 0.0015 0.0025 0.0159
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0193 0.0629 0.3449
Onchocerca volvulus 0.0119 0.0377 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0152 0.0826
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0193 0.0629 1
Brugia malayi beta-NAC-like protein 0.0112 0.0355 0.3504
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0054 0.0045
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0014 0.0066
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0234 0.1276
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0166 0.2621
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0014 0.0191
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0024 0.0054 0.0045
Echinococcus granulosus tachykinin peptides receptor 99D 0.0052 0.0152 0.0826
Schistosoma mansoni amine GPCR 0.0052 0.0152 0.0789
Schistosoma mansoni opsin-like receptor 0.0052 0.0152 0.0789
Echinococcus granulosus intermediate filament protein 0.0059 0.0176 0.0957
Leishmania major basic transcription factor 3a, putative 0.0112 0.0355 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0054 0.1526
Onchocerca volvulus 0.0043 0.012 0.3022
Onchocerca volvulus 0.0052 0.0152 0.3885
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0249 0.5333
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0024 0.0054 0.0045
Brugia malayi Dopamine receptor protein 1 0.0052 0.0152 0.1447
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0014 0.0066
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0011 0.0012
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0152 0.127
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0052 0.0152 0.1447
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0027 0.0064 0.0056
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0152 0.0789
Loa Loa (eye worm) hypothetical protein 0.0081 0.0249 0.2133
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0152 0.0826
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0027 0.0064 0.0056
Plasmodium vivax thioredoxin reductase, putative 0.0068 0.0205 0.317
Echinococcus granulosus leucyl tRNA synthetase 0.0043 0.012 0.0651
Brugia malayi follicle stimulating hormone receptor 0.0301 0.0997 1
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0152 0.0826
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0011 0.0011 0.0049
Leishmania major cytochrome p450-like protein 0.0027 0.0064 0.1603
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0176 0.1688
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0152 0.0826
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.001 0.0009 0.0115
Schistosoma mansoni opsin-like receptor 0.0052 0.0152 0.0789
Brugia malayi Protein kinase domain containing protein 0.0015 0.0026 0.0177
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus granulosus death domain containing protein 0.0015 0.0025 0.0126
Onchocerca volvulus 0.0081 0.0249 0.6526
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0027 0.0064 0.0056
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0027 0.0064 0.0056
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0054 0.073
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0043 0.012 0.3022
Trypanosoma brucei cAMP binding protein, putative 0.001 0.0009 0.0251
Leishmania major p-glycoprotein 0.0012 0.0014 0.0138
Onchocerca volvulus 0.0052 0.0152 0.3885
Echinococcus multilocularis geminin 0.0544 0.1821 1
Mycobacterium ulcerans hypothetical protein 0.0076 0.0231 0.0222
Brugia malayi hypothetical protein 0.0119 0.0377 0.3725
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0014 0.0191
Brugia malayi Cytochrome P450 family protein 0.0093 0.0288 0.2828
Loa Loa (eye worm) hypothetical protein 0.0032 0.0083 0.0655
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0193 0.0629 0.6278
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0301 0.0997 0.8772
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0152 0.0789
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0054 0.123
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0152 0.0826
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Brugia malayi nuclear hormone receptor 0.0011 0.0011 0.0022
Onchocerca volvulus 0.005 0.0144 0.3665
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0011 0.0012
Toxoplasma gondii hypothetical protein 0.005 0.0144 0.2995
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0051 0.0269
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Trichomonas vaginalis abcb9, putative 0.0012 0.0014 0.0191
Schistosoma mansoni adenoreceptor 0.0052 0.0152 0.0789
Onchocerca volvulus 0.0119 0.0377 1
Onchocerca volvulus 0.0052 0.0152 0.3885
Onchocerca volvulus 0.0052 0.0152 0.3885
Brugia malayi G-protein coupled receptor 0.0052 0.0152 0.1447
Trypanosoma brucei trypanothione reductase 0.0068 0.0205 0.5788
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0243 0.6368
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0193 0.0629 0.3423
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0027 0.0064 0.0056
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0012 0.0014 0.0191
Mycobacterium ulcerans beta-lactamase 0.0076 0.0231 0.0222
Loa Loa (eye worm) hypothetical protein 0.0081 0.0249 0.2133
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0342 0.1135 1
Onchocerca volvulus 0.0052 0.0152 0.3885
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0027 0.0064 0.1813
Onchocerca volvulus 0.0052 0.0152 0.3885
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0011 0.0051
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0054 0.0727
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0043 0.012 0.1888
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0026 0.0136
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.005 0.0144 0.2175
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0011 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0076 0.0231 0.1968
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0011 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.123
Brugia malayi larval opioid receptor 0.0052 0.0152 0.1447
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0152 0.0826
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.0355 0.5632
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0027 0.0064 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0521
Leishmania major protein farnesyltransferase alpha subunit, putative 0.005 0.0144 0.3897
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0144 0.3665
Echinococcus granulosus somatostatin receptor 0.0052 0.0152 0.0826
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0054 0.0727
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0027 0.0064 0.0056
Echinococcus granulosus cytochrome P450 2K1 0.0027 0.0064 0.0345
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0231 0.0222
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Giardia lamblia Cysteinyl-tRNA synthetase 0.0043 0.012 0.1793
Mycobacterium leprae putative cytochrome p450 0.0027 0.0064 0.0056
Onchocerca volvulus Putative organic anion transporter 0.0119 0.0377 1
Trypanosoma cruzi MFS transporter, putative 0.0119 0.0377 1
Schistosoma mansoni biogenic amine receptor 0.0052 0.0152 0.0789
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0152 0.0826
Echinococcus multilocularis somatostatin receptor 0.0052 0.0152 0.0826
Brugia malayi RNA, U transporter 1 0.0091 0.0283 0.2777
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Leishmania major importin beta-1 subunit, putative 0.0026 0.0062 0.1537
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0025 0.0089
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.005 0.0144 0.405
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0152 0.0789
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0014 0.0191
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0051 0.0231
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Plasmodium vivax glutathione reductase, putative 0.0068 0.0205 0.317
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0026 0.0155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0079 0.0243 0.385
Plasmodium falciparum cysteine--tRNA ligase 0.0043 0.012 0.1793
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0011 0.0051
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.001 0.0009 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0231 0.3648
Loa Loa (eye worm) hypothetical protein 0.0068 0.0204 0.1731
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0064 0.1507
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Echinococcus granulosus Ankyrin 0.0015 0.0025 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0027 0.0064 0.0056
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0062 0.0963
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0483 0.1613 0.1606
Brugia malayi Thioredoxin reductase 0.0068 0.0205 0.199
Schistosoma mansoni opsin-like receptor 0.0052 0.0152 0.0789
Toxoplasma gondii thioredoxin reductase 0.0068 0.0205 0.4365
Entamoeba histolytica hypothetical protein 0.0026 0.0062 0.0787
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0016 0.0037
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0152 0.0826
Echinococcus granulosus snurportin 1 0.0342 0.1135 0.623
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.014
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0027 0.0064 0.0056
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0026 0.0136
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0014 0.0066
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.005 0.0144 0.0744
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0054 0.123
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0027 0.0064 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0027 0.0064 0.0056
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0193 0.0629 0.5507
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.001 0.0009 0.004
Echinococcus granulosus agrin 0.0081 0.0249 0.136
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0052 0.0152 0.0789
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0231 0.6494
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0054 0.073
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0012 0.0013 0.0064
Echinococcus granulosus fmrfamide receptor 0.0052 0.0152 0.0826
Trypanosoma cruzi transcription factor btf3, putative 0.0112 0.0355 0.9405
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0119 0.0377 0.2063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0054 0.0458
Brugia malayi ABC transporter family protein 0.0012 0.0014 0.0048
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0152 0.0826
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0054 0.04
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0152 0.1447
Trypanosoma brucei Flagellar Member 6 0.001 0.0009 0.0251
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0231 0.1223
Loa Loa (eye worm) cytochrome P450 family protein 0.0093 0.0288 0.2481
Giardia lamblia Rab geranylgeranyltransferase 0.0193 0.0629 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0051 0.0269
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0152 0.0789
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0152 0.127
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0026 0.0136
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0078 0.0239 0.2042
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0027 0.0064 0.0056
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0054 0.0287
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0014 0.0191
Onchocerca volvulus 0.0052 0.0152 0.3885
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0042
Trichomonas vaginalis abcb9, putative 0.0012 0.0014 0.0191
Echinococcus multilocularis expressed protein 0.0081 0.0249 0.136
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0009 0.0115
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0054 0.1225
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0024 0.0054 0.0045
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0011 0.0022
Toxoplasma gondii transporter, major facilitator family protein 0.0119 0.0377 0.8172
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Schistosoma mansoni histamine h1 receptor 0.0052 0.0152 0.0789
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0152 0.0789
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0231 0.0222
Brugia malayi ecdysteroid receptor 0.0011 0.0011 0.0022
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0043 0.012 0.3384
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0152 0.0789
Onchocerca volvulus Putative organic anion transporter 0.0119 0.0377 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0011 0.0022
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Brugia malayi nuclear receptor NHR-88 0.0011 0.0011 0.0022
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0082 0.074
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0079 0.0243 0.1293
Brugia malayi Dopamine receptor protein 2 0.0052 0.0152 0.1447
Echinococcus multilocularis neuropeptide s receptor 0.0052 0.0152 0.0826
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.005 0.0144 0.3665
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0071 0.0383
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0083 0.1638
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.005 0.0144 0.405
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0043 0.012 0.1126
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.005 0.0144 0.3665
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.123
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Echinococcus multilocularis lamin dm0 0.0059 0.0176 0.0957
Plasmodium vivax basic transcription factor 3b, putative 0.0112 0.0355 0.5581
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0054 0.0045
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0025 0.014
Echinococcus granulosus cGMP dependent protein kinase 0.0011 0.0011 0.0049
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0152 0.0826
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0068 0.0205 0.0197
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0193 0.0629 0.5507
Loa Loa (eye worm) ICD-1 protein 0.0112 0.0355 0.3073
Echinococcus multilocularis Ankyrin 0.0015 0.0025 0.0129
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0027 0.0064 0.0056
Loa Loa (eye worm) CYP4Cod1 0.0093 0.0288 0.2481
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0051 0.0231
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0231 0.1258
Brugia malayi glutathione reductase 0.0068 0.0205 0.199
Echinococcus multilocularis agrin 0.0081 0.0249 0.136
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0026 0.0393
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0011 0.0012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0243 0.6368
Brugia malayi ORL1-like opioid receptor 0.0052 0.0152 0.1447
Brugia malayi SPARC precursor 0.0081 0.0249 0.2431
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0011 0.0019
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0249 0.2431
Echinococcus granulosus cGMP dependent protein kinase 1 0.0011 0.0011 0.0049
Schistosoma mansoni biogenic amine receptor 0.0052 0.0152 0.0789
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0152 0.127
Schistosoma mansoni smdr2 0.0012 0.0014 0.0026
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0026 0.0136
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0152 0.0826
Loa Loa (eye worm) cytochrome P450 0.0027 0.0064 0.0492
Echinococcus granulosus lamin dm0 0.0059 0.0176 0.0957
Giardia lamblia Rab geranylgeranyltransferase 0.005 0.0144 0.2175
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0024 0.0054 0.4069
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0152 0.0826
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0011 0.0022
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0234 0.1276
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0079 0.0243 0.2372
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0027 0.0064 0.0056
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0152 0.127
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0152 0.0789
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0051 0.0423
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0166 0.468
Schistosoma mansoni hypothetical protein 0.0056 0.0164 0.0855
Echinococcus granulosus neuropeptide receptor A26 0.0052 0.0152 0.0826
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0011 0.0051
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0011 0.0051
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0062 0.0963
Schistosoma mansoni follistatin 0.0081 0.0249 0.1325
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0014 0.0066
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Mycobacterium leprae Probable lipase LipE 0.0076 0.0231 0.0222
Schistosoma mansoni amine GPCR 0.0052 0.0152 0.0789
Onchocerca volvulus 0.0052 0.0152 0.3885
Loa Loa (eye worm) hypothetical protein 0.0076 0.0231 0.1968
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0054 0.1526
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.005 0.0144 0.0781
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0026 0.0136
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0789
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0027 0.0064 0.0056
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0012 0.0014 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0027 0.0064 0.0056
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.001 0.0009 0.004
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0026 0.0136
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Mycobacterium tuberculosis Conserved protein 0.0076 0.0231 0.0222
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0231 0.0222
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Schistosoma mansoni 60S ribosomal protein L21 0.0012 0.0016 0.0037
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0026 0.0136
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0062 0.1446
Leishmania major trypanothione reductase 0.0068 0.0205 0.568
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.123
Onchocerca volvulus 0.0012 0.0014 0.013
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0152 0.0789
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0231 0.0222
Onchocerca volvulus 0.0052 0.0152 0.3885
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0011 0.0022
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0026 0.0136
Echinococcus granulosus importin subunit beta 1 0.0032 0.0083 0.0445
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) hypothetical protein 0.0119 0.0377 0.3268
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0026 0.0155
Loa Loa (eye worm) hypothetical protein 0.0081 0.0249 0.2133
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0152 0.0826
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0152 0.3885
Mycobacterium ulcerans lipase LipD 0.0076 0.0231 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0011 0.0022
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0054 0.0287
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0166 0.0904
Onchocerca volvulus 0.0052 0.0152 0.3885
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0026 0.0096
Onchocerca volvulus 0.0052 0.0152 0.3885
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0054 0.0837
Schistosoma mansoni hypothetical protein 0.0544 0.1821 1
Leishmania major protein kinase, putative 0.0011 0.0011 0.005
Onchocerca volvulus 0.0076 0.0231 0.6023
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0014 0.0066
Schistosoma mansoni hypothetical protein 0.0544 0.1821 1
Toxoplasma gondii protease inhibitor PI2 0.0081 0.0249 0.5333
Onchocerca volvulus 0.0119 0.0377 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0011 0.0022
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0166 0.0904
Entamoeba histolytica hypothetical protein 0.0112 0.0355 0.5546
Brugia malayi AKH receptor 0.0052 0.0152 0.1447
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0083 0.0445
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0054 0.025
Loa Loa (eye worm) multidrug resistance protein 3 0.0012 0.0014 0.0042
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0027 0.0064 0.0056
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0064 0.1507
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.001 0.0009 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0521
Onchocerca volvulus 0.0119 0.0377 1
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0152 0.127
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0078 0.0239 0.2328
Leishmania major hypothetical protein, conserved 0.0076 0.0231 0.6404
Echinococcus multilocularis serotonin receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0082 0.0649
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0152 0.0826
Brugia malayi GnHR receptor homolog 0.0052 0.0152 0.1447
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0043 0.012 0.0614
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Brugia malayi Egg laying defective protein 4 0.0011 0.0011 0.0018
Trypanosoma cruzi cytochrome P450, putative 0.0093 0.0288 0.7592
Brugia malayi Serotonin receptor 0.0052 0.0152 0.1447
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0011 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0011 0.0019
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.001 0.0009 0.004
Schistosoma mansoni biogenic amine receptor 0.0052 0.0152 0.0789
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0152 0.0826
Echinococcus granulosus cysteinyl tRNA synthetase 0.0043 0.012 0.0651
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0054 0.0837
Plasmodium falciparum cGMP-dependent protein kinase 0.0011 0.0011 0.0028
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0152 0.0826
Trypanosoma brucei cytochrome P450, putative 0.0093 0.0288 0.8121
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.0355 0.5632
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Echinococcus granulosus g protein coupled receptor 0.0052 0.0152 0.0826
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.123
Schistosoma mansoni organic anion transporter 0.0119 0.0377 0.2031
Entamoeba histolytica Ran family GTPase 0.0024 0.0054 0.0655
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Onchocerca volvulus 0.0052 0.0152 0.3885
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) hypothetical protein 0.0023 0.0051 0.0371
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0081 0.0249 0.2133
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0231 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0011 0.001
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0014 0.0191
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0166 0.4272
Brugia malayi RE15519p 0.0052 0.0152 0.1447
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0152 0.0826
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0009 0.0115
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0014 0.0106
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0231 0.6023
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.005 0.0144 0.1365
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0152 0.127
Echinococcus multilocularis snurportin 1 0.0342 0.1135 0.623
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0011 0.0051
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0079 0.0243 0.1293
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0231 0.0222
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0231 0.0222
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0079 0.0243 0.1328
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Loa Loa (eye worm) AGC/PKG protein kinase 0.0011 0.0011 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0011 0.0012
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0176 0.1481
Echinococcus granulosus geminin 0.0544 0.1821 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus multilocularis neuropeptide receptor A26 0.0052 0.0152 0.0826
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0152 0.0789
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0193 0.0629 1
Leishmania major protein kinase, putative 0.0011 0.0011 0.005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0152 0.0789
Plasmodium falciparum cysteine--tRNA ligase 0.0043 0.012 0.1793
Leishmania major GTP-binding protein, putative 0.0024 0.0054 0.1302
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0231 0.2244
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0263 0.1403
Loa Loa (eye worm) hypothetical protein 0.0029 0.0071 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0166 0.2621
Echinococcus multilocularis ubiquitin specific protease 41 0.0079 0.0243 0.1328
Trichomonas vaginalis taga, putative 0.0012 0.0014 0.0191
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0079 0.0243 0.2081
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0014 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0152 0.0826
Trypanosoma brucei protein kinase, putative 0.0057 0.0166 0.468
Echinococcus granulosus serotonin receptor 0.0052 0.0152 0.0826
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0152 0.0826
Schistosoma mansoni ran 0.0024 0.0054 0.0249
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0152 0.0826
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0025 0.0159
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0009 0.0115
Plasmodium vivax cysteine--tRNA ligase, putative 0.0043 0.012 0.1793
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0011 0.0051
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0193 0.0629 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0026 0.0136
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0166 0.2621
Brugia malayi G protein-coupled receptor 0.0052 0.0152 0.1447
Toxoplasma gondii NAC domain-containing protein 0.0112 0.0355 0.7686
Onchocerca volvulus 0.0076 0.0231 0.6023
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus granulosus cGMP dependent protein kinase 1 0.0011 0.0011 0.0049
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0166 0.3491
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0054 0.073
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0231 0.0222
Trichomonas vaginalis esterase, putative 0.0076 0.0231 0.3648
Echinococcus granulosus thioredoxin glutathione reductase 0.0068 0.0205 0.112
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0027 0.0064 0.0056
Loa Loa (eye worm) hypothetical protein 0.0119 0.0377 0.3268
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0027 0.0064 0.0056
Brugia malayi secreted modular calcium-binding protein 1 0.0081 0.0249 0.2431
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.123
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0152 0.0826
Plasmodium falciparum multidrug resistance protein 1 0.0012 0.0014 0.0077
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.001 0.0009 0.004
Echinococcus granulosus patatin phospholipase domain containing protein 0.001 0.0009 0.004
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0014 0.0066
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0249 0.2431
Brugia malayi neuropeptide F receptor 0.0052 0.0152 0.1447
Echinococcus granulosus protein prenyltransferase alpha subunit 0.005 0.0144 0.0781
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0011 0.0022
Schistosoma mansoni intermediate filament proteins 0.0059 0.0176 0.092
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0027 0.0064 0.0056
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0152 0.0826
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0193 0.0629 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0011 0.0012
Plasmodium vivax importin-beta 2, putative 0.0032 0.0083 0.119
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0078 0.0239 0.1304
Brugia malayi multidrug resistance protein 3 0.0012 0.0014 0.0048
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0152 0.1447
Echinococcus granulosus g protein coupled receptor 0.0052 0.0152 0.0826
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0027 0.0064 0.0056
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0152 0.1447
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0152 0.0826
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0152 0.1447
Schistosoma mansoni coup transcription factor 0.0011 0.0011 0.0012
Schistosoma mansoni ran 0.0024 0.0054 0.0249
Echinococcus multilocularis musashi 0.0059 0.0176 0.0957
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0144
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0027 0.0064 0.0056
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0051 0.0269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0011 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0076 0.0231 0.1968
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0152 0.0826
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0011 0.0051
Schistosoma mansoni lamin 0.0059 0.0176 0.092
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0013 0.0064
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.005 0.0144 0.2175
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0011 0.0051
Echinococcus granulosus cyclic nucleotide gated cation channel 0.001 0.0009 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0027 0.0064 0.0056
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0079 0.0243 0.1328
Brugia malayi Cytochrome P450 family protein 0.0027 0.0064 0.0561
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0221 0.3503
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.001 0.0009 0.0251
Onchocerca volvulus 0.0076 0.0231 0.6023
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0152 0.1447
Brugia malayi beta-lactamase family protein 0.0076 0.0231 0.2244
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0249 0.2431
Schistosoma mansoni neuropeptide receptor 0.0052 0.0152 0.0789
Echinococcus multilocularis follistatin 0.0081 0.0249 0.136
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0014 0.0066
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0079 0.0243 0.3779
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Schistosoma mansoni lamin 0.0059 0.0176 0.092
Onchocerca volvulus 0.0059 0.0176 0.4532
Leishmania major cysteinyl-tRNA synthetase, putative 0.0043 0.012 0.3214
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0231 0.0222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0166 0.1396
Trypanosoma brucei cAMP response protein 1, putative 0.001 0.0009 0.0251
Loa Loa (eye worm) cytochrome P450 family protein 0.0093 0.0288 0.2481
Echinococcus granulosus allatostatin A receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0119 0.0377 0.3268
Echinococcus granulosus Solute carrier organic anion transporter family 0.0119 0.0377 0.2063
Schistosoma mansoni hypothetical protein 0.0052 0.0152 0.0789
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0152 0.0826
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0043 0.012 0.3022
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0166 0.4272
Echinococcus multilocularis serotonin receptor 0.0052 0.0152 0.0826
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0062 0.0963
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0152 0.0826
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0027 0.0064 0.0056
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Onchocerca volvulus 0.0052 0.0152 0.3885
Loa Loa (eye worm) agrin synaptic family protein 0.0081 0.0249 0.2133
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0011 0.0051
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0152 0.0826
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0081 0.0249 0.2431
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0025 0.0126
Schistosoma mansoni importin beta-1 0.0032 0.0083 0.0407
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0012 0.0014 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0152 0.0826
Trypanosoma brucei transcription factor BTF3, putative 0.0112 0.0355 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0024 0.0054 0.073
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0043 0.012 0.247
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.2951 1 1
Brugia malayi hypothetical protein 0.0052 0.0152 0.1447
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0014 0.0066
Schistosoma mansoni agrin 0.0081 0.0249 0.1325
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0263 0.1403
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0027 0.0064 0.0056
Echinococcus granulosus transcription factor btf3 0.0112 0.0355 0.1942
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0152 0.0826
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0025 0.0126
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) hypothetical protein 0.0081 0.0249 0.2133
Loa Loa (eye worm) beta-lactamase 0.0076 0.0231 0.1968
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0152 0.127
Plasmodium falciparum glutathione reductase 0.0068 0.0205 0.317
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.005 0.0144 0.0781
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0054 0.1225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0152 0.0789
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0054 0.123
Echinococcus granulosus g protein coupled receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0152 0.127
Trichomonas vaginalis ran, putative 0.0024 0.0054 0.0833
Toxoplasma gondii hypothetical protein 0.0143 0.0459 1
Schistosoma mansoni amine GPCR 0.0052 0.0152 0.0789
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0152 0.0789
Echinococcus multilocularis sex peptide receptor 0.0052 0.0152 0.0826
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0019
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0079 0.0243 0.373
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0014 0.0191
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0119 0.0377 0.2063
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0152 0.0826
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.0355 0.5632
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0014 0.0191
Onchocerca volvulus Putative organic anion transporter 0.0119 0.0377 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Plasmodium falciparum basic transcription factor 3b, putative 0.0112 0.0355 0.5581
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0014 0.0191
Schistosoma mansoni myosin xvIII 0.0052 0.0152 0.0789
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0166 0.0904
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0078 0.0239 0.1304
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.127
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0166 0.4543
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0011 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0011 0.0022
Schistosoma mansoni neuropeptide receptor 0.0052 0.0152 0.0789
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0143 0.0459 0.7293
Plasmodium falciparum thioredoxin reductase 0.0024 0.0054 0.073
Brugia malayi steroid hormone receptor 0.0011 0.0011 0.0022
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0014 0.0191
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0017 0.0033 0.0243
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0014 0.0191
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0152 0.0789
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0011 0.0022
Loa Loa (eye worm) thioredoxin reductase 0.0068 0.0205 0.1746
Brugia malayi Importin beta-1 subunit 0.0032 0.0083 0.0747
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.005 0.0144 0.405
Loa Loa (eye worm) hypothetical protein 0.0043 0.012 0.0988
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0152 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0011 0.0022
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0152 0.0826
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0231 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0166 0.0868
Echinococcus granulosus follistatin 0.0081 0.0249 0.136
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0043 0.012 0.0651
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0054 0.123
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0054 0.1526

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1 uM Inhibition of farnesyl transferase ChEMBL. No reference
IC50 (binding) = 1 uM Inhibition of farnesyl transferase ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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