Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.3612 | 0.3612 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.3612 | 0.3612 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0106 | 0.0198 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.3612 | 0.6733 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.3612 | 0.3612 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3612 | 0.6733 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.3974 | 0.3974 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.3974 | 0.7407 |
Onchocerca volvulus | Huntingtin homolog | 0.0131 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.3612 | 0.3612 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0106 | 0.0198 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0106 | 0.0106 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3612 | 0.6733 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0106 | 0.0198 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0106 | 0.0198 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3612 | 0.6733 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0085 | 0.5365 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3612 | 0.6733 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0106 | 0.0198 |
Brugia malayi | RNA binding protein | 0.0068 | 0.3612 | 0.3612 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.7307 | 0.7307 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.3612 | 0.6733 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0106 | 0.0198 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0106 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.7307 | 0.7307 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.7307 | 0.7307 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.7307 | 0.7307 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0106 | 0.0198 |
Onchocerca volvulus | Huntingtin homolog | 0.0131 | 1 | 1 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0085 | 0.5365 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 1 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3974 | 0.3974 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.5365 | 0.5365 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.3612 | 0.3612 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0085 | 0.5365 | 1 |
Onchocerca volvulus | 0.0085 | 0.5365 | 0.5365 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3612 | 0.6733 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 1 | 1 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0085 | 0.5365 | 0.5365 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0106 | 0.0198 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0106 | 0.0198 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0106 | 0.0106 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.