Detailed information for compound 1546977

Basic information

Technical information
  • TDR Targets ID: 1546977
  • Name: N,N-dimethyl-5-(thiophen-2-ylmethylimino)-1,2 ,4-dithiazol-3-amine hydrobromide
  • MW: 338.311 | Formula: C9H12BrN3S3
  • H donors: 0 H acceptors: 0 LogP: 3.09 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1ssc(=NCc2cccs2)n1)C.Br
  • InChi: 1S/C9H11N3S3.BrH/c1-12(2)9-11-8(14-15-9)10-6-7-4-3-5-13-7;/h3-5H,6H2,1-2H3;1H
  • InChiKey: BQUMDURJWIQSOG-UHFFFAOYSA-N  

Network

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Synonyms

  • N,N-dimethyl-5-(2-thienylmethylimino)-1,2,4-dithiazol-3-amine hydrobromide
  • dimethyl-[5-(2-thenylimino)-1,2,4-dithiazol-3-yl]amine hydrobromide
  • NSC661110

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor Starlite/ChEMBL No references
Human immunodeficiency virus 1 Aberrant vpr protein Starlite/ChEMBL No references
Homo sapiens glutaminase Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Plasmodium berghei glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium yoelii Glucose-6-phosphate dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Loa Loa (eye worm) glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis 6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Theileria parva glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium knowlesi glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma brucei gambiense glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Neospora caninum Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49), related Get druggable targets OG5_127121 All targets in OG5_127121
Loa Loa (eye worm) glutaminase 2 Get druggable targets OG5_129245 All targets in OG5_129245
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi glutaminase DH11.1 Get druggable targets OG5_129245 All targets in OG5_129245
Leishmania braziliensis glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma japonicum ko:K00036 glucose-6-phosphate 1-dehydrogenase [EC1.1.1.49], putative Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Neospora caninum Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49), related Get druggable targets OG5_127121 All targets in OG5_127121
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Babesia bovis glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania donovani glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Leishmania mexicana glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis glutaminase, putative Get druggable targets OG5_129245 All targets in OG5_129245
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi glucose-6-phosphate dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) Get druggable targets OG5_127121 All targets in OG5_127121
Treponema pallidum glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Candida albicans likely glucose-6-phosphate dehydrogenase similar to S. cerevisiae ZWF1 (YNL241C) Get druggable targets OG5_127121 All targets in OG5_127121
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase Get druggable targets OG5_127121 All targets in OG5_127121
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Get druggable targets OG5_127121 All targets in OG5_127121
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans likely glucose-6-phosphate dehydrogenase similar to S. cerevisiae ZWF1 (YNL241C) Get druggable targets OG5_127121 All targets in OG5_127121
Mycobacterium ulcerans glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Plasmodium berghei glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, putative Get druggable targets OG5_127121 All targets in OG5_127121
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma congolense glucose-6-phosphate 1-dehydrogenase, putative Get druggable targets OG5_127121 All targets in OG5_127121

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi steroid hormone receptor vitamin D (1,25- dihydroxyvitamin D3) receptor 427 aa 416 aa 24.5 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0037 0.0053 0.0039
Brugia malayi bZIP transcription factor family protein 0.027 0.0905 0.2456
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0337 0.119
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0068 0.0054
Echinococcus granulosus geminin 0.0679 0.2402 0.3044
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni RAR-like nuclear receptor 0.0064 0.0148 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.003 0.0025 0.0059
Brugia malayi hypothetical protein 0.0034 0.0039 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0082 0.0215 0.0556
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2756 1 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.013 0.0393 0.0497
Brugia malayi hypothetical protein 0.0052 0.0105 0.0252
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.002 0.0055
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0123 0.0365 0.1261
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0061 0.0138 0.0174
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.0597 0.0756
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Loa Loa (eye worm) carboxylesterase 0.0064 0.0149 0.0374
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0206 0.0669 0.0669
Toxoplasma gondii cytochrome p450 superfamily protein 0.003 0.0025 0.0067
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0181 0.0168
Schistosoma mansoni acetylcholinesterase 0.0064 0.0149 0.0188
Loa Loa (eye worm) hypothetical protein 0.0161 0.0506 0.1357
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0577 0.2065
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0359 0.5361
Echinococcus granulosus somatostatin receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0197 0.0636 0.2307
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0104 0.0104
Echinococcus multilocularis geminin 0.0679 0.2402 0.3044
Treponema pallidum oxidoreductase 0.0206 0.0669 0.243
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0202 0.0699
Onchocerca volvulus 0.0104 0.0296 0.1043
Echinococcus granulosus g-protein coupled receptor 0.0061 0.0138 0.0174
Leishmania major hypothetical protein, conserved 0.0051 0.0104 0.0104
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0113 0.0328 0.0315
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0613 0.2195
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0197 0.0636 0.0805
Onchocerca volvulus Neuropeptide F receptor homolog 0.0061 0.0138 0.0453
Schistosoma mansoni ankyrin 23/unc44 0.003 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0064 0.0149 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0021 0.0037
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0206 0.0669 0.1614
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0048 0.0132
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0616 0.078
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0041 0.0068 0.0054
Onchocerca volvulus 0.004 0.0063 0.0174
Echinococcus multilocularis somatostatin receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.011 0.0319 0.0842
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0044 0.0055
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0319 0.0306
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0206 0.0669 0.0848
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0049 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0046 0.0131
Brugia malayi Carboxylesterase family protein 0.0064 0.0149 0.0373
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0104 0.0091
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0061 0.0138 0.0343
Echinococcus granulosus death domain containing protein 0.003 0.0027 0.0034
Onchocerca volvulus 0.0061 0.0138 0.0453
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0138 0.0174
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0275 0.0924 0.2508
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0105 0.0252
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0148 0.0188
Loa Loa (eye worm) hypothetical protein 0.0034 0.0039 0.0071
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0091 0.1365
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0048 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0034 0.0084
Schistosoma mansoni nuclear receptor 0.003 0.0026 0.0032
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0058 0.016
Mycobacterium ulcerans monoxygenase 0.0206 0.0669 0.243
Echinococcus granulosus lamin 0.0057 0.0125 0.0158
Loa Loa (eye worm) hypothetical protein 0.0064 0.0149 0.0374
Schistosoma mansoni hypothetical protein 0.0079 0.0203 0.0257
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0044 0.0122
Echinococcus multilocularis glutamate synthase 0.0206 0.0669 0.0848
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0206 0.0669 0.243
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0206 0.0669 0.0669
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0206 0.0669 0.1614
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0005 0.0015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0776 0.2754 1
Brugia malayi Nuclear hormone receptor E75 0.003 0.0026 0.0034
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0776 0.2754 0.7561
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0064 0.0148 0.0188
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0007 0.002
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0091 0.0115
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0197 0.0636 0.0805
Brugia malayi Blistered cuticle protein 3 0.0052 0.0105 0.0252
Leishmania major ATP-dependent phosphofructokinase 0.0121 0.0359 0.0359
Schistosoma mansoni hypothetical protein 0.0038 0.0055 0.0069
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0013 0.0017
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0206 0.0669 0.1614
Schistosoma mansoni hypothetical protein 0.0061 0.0138 0.0174
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0206 0.0669 0.1838
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0039 0.0071
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0044
Brugia malayi Augmenter of liver regeneration 0.0036 0.0048 0.0096
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0776 0.2754 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0944 0.3369 0.4269
Leishmania major hypothetical protein, conserved 0.0206 0.0669 0.0669
Schistosoma mansoni coup transcription factor 0.0064 0.0148 0.0188
Onchocerca volvulus 0.0061 0.0138 0.0453
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0138 0.0174
Brugia malayi ecdysteroid receptor 0.0064 0.0148 0.0372
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0206 0.0669 0.0669
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0101 0.0087
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0206 0.0669 0.243
Trichomonas vaginalis glutaminase, putative 0.033 0.1124 0.4058
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0131 0.0324
Schistosoma mansoni retinoic acid receptor RXR 0.0064 0.0148 0.0188
Echinococcus multilocularis carboxylesterase 5A 0.0376 0.1293 0.1639
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0125 0.0309
Schistosoma mansoni sulfide quinone reductase 0.0206 0.0669 0.0848
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0206 0.0669 0.2401
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.0254 0.0321
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0267 0.0337
Plasmodium vivax glutathione reductase, putative 0.1018 0.3643 1
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0013 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0616 0.078
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0044 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0319 0.1123
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0061 0.0138 0.0343
Schistosoma mansoni alpha-glucosidase 0.0136 0.0413 0.0523
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0161 0.0506 0.064
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.007 0.0088
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0181 0.0229
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0196 0.0504
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0036 0.0091
Echinococcus granulosus serotonin transporter 0.0161 0.0506 0.064
Brugia malayi Tachykinin-like peptides receptor 99D 0.0061 0.0138 0.0342
Entamoeba histolytica disulphide oxidoreductase, putative 0.0206 0.0669 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0206 0.0669 0.243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0066 0.0201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0064 0.0148 0.0373
Brugia malayi Steroid receptor seven-up type 2 0.0064 0.0148 0.0372
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0026 0.0032
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.003 0.0025 0.0059
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0206 0.0669 0.1614
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0319 0.1123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0088 0.0111
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0319 0.1123
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Brugia malayi nuclear receptor RXR 0.003 0.0026 0.0034
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0026 0.0032
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0138 0.0174
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0026 0.0032
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0181 0.0463
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0068 0.0151
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Onchocerca volvulus 0.0109 0.0313 0.1107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.002 0.0034
Loa Loa (eye worm) acetylcholinesterase 1 0.0376 0.1293 0.3527
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0055 0.0069
Echinococcus granulosus g protein coupled receptor 0.0061 0.0138 0.0174
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0036 0.0057
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0026 0.0035
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0091 0.0216
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.004 0.0063 0.0079
Brugia malayi Serotonin receptor 0.0551 0.1933 0.5288
Mycobacterium ulcerans carboxylesterase, LipT 0.0064 0.0149 0.054
Treponema pallidum thioredoxin reductase (trxB) 0.0206 0.0669 0.243
Onchocerca volvulus 0.0061 0.0138 0.0453
Echinococcus granulosus carboxylesterase 5A 0.0376 0.1293 0.1639
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0013 0.0017
Leishmania major C-8 sterol isomerase-like protein 0.0393 0.1353 0.1353
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0203 0.0257
Schistosoma mansoni amine GPCR 0.059 0.2076 0.2631
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0027 0.0016 0.002
Leishmania major lanosterol 14-alpha-demethylase, putative 0.003 0.0025 0.0025
Mycobacterium ulcerans putative regulatory protein 0.0114 0.0334 0.1212
Brugia malayi hypothetical protein 0.0509 0.1778 0.4862
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0197 0.0636 0.2307
Brugia malayi nuclear receptor NHR-88 0.0064 0.0148 0.0372
Echinococcus granulosus sex peptide receptor 0.0061 0.0138 0.0174
Schistosoma mansoni hypothetical protein 0.0206 0.0669 0.0848
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0206 0.0669 0.2401
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0016 0.002
Echinococcus granulosus cytochrome P450 2K1 0.003 0.0025 0.0031
Brugia malayi serine/threonine-protein kinase plk-2 0.0115 0.0337 0.0891
Trypanosoma brucei polo-like protein kinase 0.0115 0.0337 0.0337
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0027 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0061 0.0138 0.0174
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0056 0.0056
Echinococcus granulosus 6 phosphofructokinase 0.0121 0.0359 0.0454
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0016 0.002
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.003 0.0025 0.0059
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0012
Brugia malayi GnHR receptor homolog 0.0061 0.0138 0.0342
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.004 0.0063 0.0049
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0206 0.0669 0.2401
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0206 0.0669 0.2401
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0196 0.0183
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0061 0.0138 0.0174
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0206 0.0669 0.1614
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0776 0.2754 0.7561
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0493 0.0625
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0044
Schistosoma mansoni neuroligin 3 (S09 family) 0.0064 0.0149 0.0188
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0105 0.0252
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0248 0.0824 0.2234
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0206 0.0669 0.0657
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0616 0.078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0008
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0016 0.002
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.011 0.0319 0.0319
Schistosoma mansoni hypothetical protein 0.013 0.0393 0.0497
Loa Loa (eye worm) melatonin receptor type 1A 0.0061 0.0138 0.0343
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0016 0.002
Echinococcus multilocularis lamin dm0 0.0057 0.0125 0.0158
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0148 0.0188
Giardia lamblia NADH oxidase lateral transfer candidate 0.0776 0.2754 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0088 0.0111
Schistosoma mansoni alpha-glucosidase 0.0136 0.0413 0.0523
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0202 0.0202
Schistosoma mansoni steroid hormone receptor ad4bp 0.0064 0.0148 0.0188
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.027 0.0905 0.1146
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0196 0.0248
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Loa Loa (eye worm) doublecortin family protein 0.013 0.0393 0.1045
Echinococcus granulosus jun protein 0.027 0.0905 0.1146
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Echinococcus granulosus lipoxygenase domain containing protein 0.013 0.0393 0.0497
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0064 0.0148 0.0373
Brugia malayi hypoxia-induced factor 1 0.0478 0.1664 0.4547
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.0309
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0064 0.0148 0.0372
Echinococcus multilocularis conserved hypothetical protein 0.0736 0.2609 0.3306
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0044 0.0044
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0113 0.0328 0.1191
Brugia malayi nuclear receptor NHR-67 0.003 0.0026 0.0034
Mycobacterium ulcerans NADH dehydrogenase 0.0206 0.0669 0.243
Brugia malayi hypothetical protein 0.0518 0.1811 0.4952
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0027 0.0016 0.002
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.003 0.0025 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0064 0.0148 0.0372
Echinococcus granulosus phd:f box containing protein 0.0027 0.0013 0.0017
Plasmodium falciparum glutathione reductase 0.0776 0.2754 0.7561
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.003 0.0025 0.0059
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0359 0.0346
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.005 0.0099 0.0237
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0206 0.0669 0.1807
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.057 0.2001 0.5476
Echinococcus multilocularis lipoxygenase domain containing protein 0.013 0.0393 0.0497
Schistosoma mansoni BC026374 protein (S09 family) 0.0064 0.0149 0.0188
Brugia malayi Pre-SET motif family protein 0.0668 0.236 0.6466
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.004 0.0063 0.0228
Echinococcus multilocularis G protein coupled receptor 139 0.0061 0.0138 0.0174
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.002 0.0025
Plasmodium falciparum transporter, putative 0.0027 0.0016 0.0044
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0067 0.0054
Trichomonas vaginalis glutamate synthase, putative 0.0206 0.0669 0.2401
Echinococcus multilocularis netrin receptor unc 5 0.003 0.0027 0.0034
Brugia malayi glutamate synthase 0.0206 0.0669 0.1807
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0123 0.0365 0.1291
Echinococcus granulosus peroxidasin 0.0052 0.0105 0.0132
Brugia malayi Protein kinase domain containing protein 0.0032 0.0032 0.0052
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0587 0.2063 0.4974
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.003 0.0025 0.0059
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0064 0.0148 0.0188
Echinococcus granulosus dro:myosuppressin receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0075 0.0235
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0181 0.0229
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.003 0.0025 0.0059
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0776 0.2754 1
Brugia malayi RE15519p 0.0061 0.0138 0.0342
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0027 0.0016 0.0007
Loa Loa (eye worm) hypothetical protein 0.0248 0.0824 0.2234
Trichomonas vaginalis mercuric reductase, putative 0.0776 0.2754 1
Echinococcus granulosus orexin receptor type 2 0.0061 0.0138 0.0174
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0113 0.0328 0.0415
Loa Loa (eye worm) hypothetical protein 0.0079 0.0203 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0046 0.0131
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0206 0.0669 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0359 0.0953
Echinococcus granulosus chromobox protein 1 0.0078 0.02 0.0253
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0061 0.0138 0.0174
Loa Loa (eye worm) glutaminase 0.033 0.1124 0.306
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.0616 0.166
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0064 0.0149 0.0188
Echinococcus multilocularis RUN 0.013 0.0393 0.0497
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0039 0.0059 0.0142
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0074 0.0185 0.0508
Trichomonas vaginalis chromobox protein, putative 0.0078 0.02 0.069
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0067 0.0054
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0196 0.0196
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0061 0.0138 0.0174
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.003 0.0025 0.0089
Brugia malayi jmjC domain containing protein 0.0159 0.0496 0.133
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0113 0.0328 0.0868
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0138 0.0174
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0027 0.0016 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.003 0.0025 0.0059
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0181 0.0181
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.003 0.0025 0.0011
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0202 0.0699
Onchocerca volvulus 0.0114 0.0334 0.1185
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0597 0.2166
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0105 0.0252
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0138 0.0174
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0123 0.0365 0.1001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Mycobacterium tuberculosis Probable dehydrogenase 0.0587 0.2063 0.4974
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Echinococcus granulosus survival motor neuron protein 1 0.0509 0.1778 0.2253
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0196 0.0196
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0196 0.0538
Loa Loa (eye worm) hypothetical protein 0.0064 0.0149 0.0374
Echinococcus multilocularis microtubule associated protein 2 0.2179 0.7891 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0048 0.0035
Onchocerca volvulus 0.0161 0.0506 0.1825
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0104 0.0286
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0013 0.0017
Giardia lamblia GTOR 0.0048 0.0091 0.0261
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Brugia malayi Death domain containing protein 0.003 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0376 0.1293 0.3527
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0061 0.0138 0.0342
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0028 0.0035
Brugia malayi hypothetical protein 0.003 0.0026 0.0034
Echinococcus granulosus tachykinin peptides receptor 99D 0.0061 0.0138 0.0174
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0036 0.0048 0.006
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Echinococcus granulosus lipoxygenase domain containing protein 0.013 0.0393 0.0497
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0123 0.0365 0.1001
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0577 0.2065
Brugia malayi glutathione reductase 0.1018 0.3643 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Brugia malayi phosphofructokinase 0.0121 0.0359 0.0952
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0267 0.0337
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.002 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0616 0.078
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0064 0.0149 0.0188
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0359 0.1269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0064 0.0148 0.0373
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0064 0.0148 0.0188
Giardia lamblia Kinase, CMGC MAPK 0.011 0.0319 0.1092
Schistosoma mansoni opsin-like receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0138 0.0174
Brugia malayi nuclear receptor NHR-88 0.003 0.0026 0.0034
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0026 0.0032
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0087 0.0265
Brugia malayi hypothetical protein 0.013 0.0393 0.1044
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0196 0.0712
Echinococcus multilocularis lamin 0.0057 0.0125 0.0158
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0057 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0126 0.0422
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0064 0.0148 0.0372
Loa Loa (eye worm) hypothetical protein 0.019 0.0613 0.1652
Echinococcus granulosus lamin dm0 0.0057 0.0125 0.0158
Onchocerca volvulus 0.0064 0.0149 0.0494
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0206 0.0669 0.1838
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0206 0.0669 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0046 0.0131
Brugia malayi cytochrome P450 0.003 0.0025 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0039 0.007
Loa Loa (eye worm) steroid hormone receptor 0.0064 0.0148 0.0373
Brugia malayi Carboxylesterase family protein 0.0376 0.1293 0.3527
Onchocerca volvulus 0.0052 0.0105 0.033
Echinococcus granulosus G protein coupled receptor 139 0.0061 0.0138 0.0174
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0206 0.0669 0.0848
Loa Loa (eye worm) DR-78 0.003 0.0026 0.0035
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0161 0.0506 0.1356
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0026 0.0032
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0016 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0061 0.0138 0.0174
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0186 0.0597 0.1439
Loa Loa (eye worm) RecQ helicase 0.0042 0.0068 0.0152
Toxoplasma gondii selenide, water dikinase 0.0206 0.0669 0.1838
Echinococcus granulosus single minded 2 0.0118 0.0347 0.0439
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0105 0.0253
Chlamydia trachomatis thioredoxin reductase 0.0206 0.0669 0.243
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.232 0.8406 0.8406
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0159 0.0496 0.0628
Echinococcus multilocularis serotonin transporter 0.0161 0.0506 0.064
Schistosoma mansoni glutamate synthase 0.0206 0.0669 0.0848
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0064 0.0148 0.0373
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0064 0.0148 0.0188
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.003 0.0025 0.0089
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Brugia malayi Inositol-1 0.0078 0.0202 0.0521
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.027 0.0905 0.1146
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0044 0.0031
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0206 0.0669 0.243
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0064 0.0148 0.0188
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.004 0.0063 0.0137
Echinococcus multilocularis lysine specific demethylase 5A 0.01 0.0281 0.0356
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0202 0.0699
Onchocerca volvulus 0.0061 0.0138 0.0453
Leishmania major trypanothione reductase 0.1018 0.3643 0.3643
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0091 0.0295
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.02 0.0515
Schistosoma mansoni hypothetical protein 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0057 0.0043
Schistosoma mansoni DNA helicase recq5 0.0028 0.002 0.0025
Echinococcus granulosus g protein coupled receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0064 0.0149 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.003 0.0025 0.0059
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.003 0.0025 0.0011
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0026 0.0032
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.005 0.0099 0.0125
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0036 0.0098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0088 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0075 0.0235
Brugia malayi intermediate filament protein 0.0057 0.0125 0.0308
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.002 0.0055
Onchocerca volvulus 0.0061 0.0138 0.0453
Schistosoma mansoni hypothetical protein 0.0679 0.2402 0.3044
Echinococcus granulosus bloom syndrome protein 0.0042 0.0068 0.0086
Schistosoma mansoni neuropeptide receptor 0.0061 0.0138 0.0174
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0104 0.0296 0.0778
Leishmania major hypothetical protein, conserved 0.0206 0.0669 0.0669
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.0577 0.2092
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0061 0.0138 0.0342
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0074 0.0185 0.0672
Onchocerca volvulus 0.0064 0.0149 0.0494
Trypanosoma brucei trypanothione reductase 0.1018 0.3643 0.3643
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0206 0.0669 0.243
Brugia malayi PHD-finger family protein 0.0028 0.002 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0091 0.0295
Onchocerca volvulus Bile acid receptor homolog 0.0064 0.0148 0.0493
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0039 0.0049
Loa Loa (eye worm) hypothetical protein 0.0353 0.1209 0.3294
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0493 0.0625
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0105 0.0252
Trypanosoma brucei glucosidase, putative 0.0035 0.0044 0.0044
Echinococcus multilocularis 6 phosphofructokinase 0.0121 0.0359 0.0454
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0503 0.1758 0.2228
Echinococcus granulosus 7tm_1 domain containing protein 0.0061 0.0138 0.0174
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0196 0.0183
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0206 0.0669 0.1838
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0064 0.0148 0.0188
Schistosoma mansoni myosin xvIII 0.0061 0.0138 0.0174
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0206 0.0669 0.0848
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0036 0.0098
Echinococcus granulosus potassium voltage gated channel subfamily H 0.005 0.0099 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Trypanosoma cruzi NADH dehydrogenase, putative 0.0206 0.0669 0.0657
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.004 0.0063 0.019
Entamoeba histolytica thioredoxin reductase, putative 0.0206 0.0669 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0039 0.0071
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0337 0.119
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0016 0.002
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.004 0.0063 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.019
Brugia malayi PAS domain containing protein 0.0154 0.0481 0.1287
Echinococcus multilocularis mitogen activated protein kinase 0.011 0.0319 0.0403
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2029 0.7339 0.7336
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.004 0.0063 0.019
Echinococcus multilocularis thioredoxin glutathione reductase 0.1019 0.3646 0.4621
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.004 0.0063 0.019
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0206 0.0669 0.0657
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0186 0.0597 0.0756
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0206 0.0669 0.2401
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0013 0.0037
Onchocerca volvulus 0.0061 0.0138 0.0453
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) TYRA-2 protein 0.0061 0.0138 0.0343
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Giardia lamblia Kinase, PLK 0.0115 0.0337 0.1159
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0138 0.0174
Toxoplasma gondii hypothetical protein 0.0027 0.0016 0.0044
Echinococcus granulosus fmrfamide receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0206 0.0669 0.1808
Brugia malayi hypothetical protein 0.0033 0.0038 0.0066
Loa Loa (eye worm) cytochrome P450 0.003 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni hypothetical protein 0.0079 0.0203 0.0257
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0036 0.0532
Schistosoma mansoni glutaminase 0.033 0.1124 0.1424
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0196 0.0676
Brugia malayi chromobox protein homolog 3 0.0043 0.0075 0.017
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0036 0.0091
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0064 0.0148 0.0188
Brugia malayi putative neuropeptide receptor NPR1 0.0061 0.0138 0.0342
Schistosoma mansoni neuropeptide receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0011 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0044 0.0031
Entamoeba histolytica hypothetical protein 0.0038 0.0055 0.0815
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) jmjC domain-containing protein 0.01 0.0281 0.0739
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0007
Loa Loa (eye worm) hypothetical protein 0.0509 0.1778 0.4863
Giardia lamblia Glutamate synthase 0.0206 0.0669 0.2375
Schistosoma mansoni lamin 0.0057 0.0125 0.0158
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0017 0.0021
Brugia malayi Carboxylesterase family protein 0.0064 0.0149 0.0373
Brugia malayi Carboxylesterase family protein 0.0064 0.0149 0.0373
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0013 0.0013
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0095 0.0225
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0064 0.0148 0.0188
Onchocerca volvulus 0.0212 0.0693 0.2522
Onchocerca volvulus 0.003 0.0026 0.0036
Brugia malayi MAP kinase sur-1 0.011 0.0319 0.0841
Plasmodium vivax ferrodoxin reductase, putative 0.0206 0.0669 0.1838
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0924 0.3328
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0138 0.0174
Plasmodium vivax multidomain scavenger receptor, putative 0.013 0.0393 0.1078
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Echinococcus granulosus biogenic amine 5HT receptor 0.019 0.0613 0.0776
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0055 0.0164
Echinococcus granulosus allatostatin A receptor 0.0061 0.0138 0.0174
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0206 0.0669 0.1838
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0001
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0036 0.0091
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0493 0.0625
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0042
Schistosoma mansoni hypothetical protein 0.0061 0.0138 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.003 0.0025 0.0059
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0206 0.0669 0.2401
Onchocerca volvulus Netrin receptor homolog 0.003 0.0027 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.232 0.8406 0.8404
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.003 0.0025 0.0059
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.011 0.0319 0.0875
Loa Loa (eye worm) phosphofructokinase 0.0121 0.0359 0.0953
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0064 0.0149 0.0359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0011 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0493 0.1322
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0577 0.2065
Onchocerca volvulus Serine\/threonine kinase homolog 0.0115 0.0337 0.1196
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0587 0.2063 0.4974
Trypanosoma brucei NADH dehydrogenase 0.0206 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0502 0.1753 0.4794
Echinococcus granulosus g protein coupled receptor 0.0061 0.0138 0.0174
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.0027 0.0034
Onchocerca volvulus 0.0064 0.0148 0.0493
Loa Loa (eye worm) hypothetical protein 0.0064 0.0149 0.0374
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.004 0.0063 0.019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Schistosoma mansoni peroxidasin 0.0052 0.0105 0.0132
Echinococcus granulosus aryl hydrocarbon receptor 0.004 0.0063 0.0079
Echinococcus granulosus alpha 1A adrenergic receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis adenylate cyclase, putative 0.004 0.0063 0.019
Onchocerca volvulus 0.0061 0.0138 0.0453
Brugia malayi Peroxidasin 0.0052 0.0105 0.0252
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0776 0.2754 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.002 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.003 0.0025 0.0059
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0064 0.0148 0.0188
Onchocerca volvulus 0.0057 0.0125 0.0406
Schistosoma mansoni amine GPCR 0.0061 0.0138 0.0174
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0112 0.0141
Schistosoma mansoni chromobox protein 0.0078 0.02 0.0253
Brugia malayi glutaminase DH11.1 0.033 0.1124 0.306
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0064 0.0148 0.0188
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.011 0.0319 0.0306
Brugia malayi glucose-6-phosphate dehydrogenase 0.0113 0.0328 0.0867
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0359 0.1269
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0029 0.0066
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0426 0.0413
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0319 0.0403
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0267 0.0337
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0061 0.0138 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0055 0.0164
Onchocerca volvulus 0.0061 0.0138 0.0453
Loa Loa (eye worm) hypothetical protein 0.004 0.0063 0.0137
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0027 0.004
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0616 0.078
Onchocerca volvulus 0.0061 0.0138 0.0453
Onchocerca volvulus Peroxidasin homolog 0.0052 0.0105 0.033
Schistosoma mansoni histamine h1 receptor 0.0061 0.0138 0.0174
Brugia malayi nuclear receptor RXR 0.0034 0.0039 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0046 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0091 0.0295
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0026 0.0036
Brugia malayi neuropeptide F receptor 0.0061 0.0138 0.0342
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0426 0.0426
Echinococcus granulosus mitogen activated protein kinase 0.011 0.0319 0.0403
Echinococcus granulosus netrin receptor unc 5 0.003 0.0027 0.0034
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0138 0.0343
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.003 0.003
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.0789 0.2137
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0206 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0337 0.119
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0785 0.279 0.3535
Trypanosoma cruzi polo-like protein kinase, putative 0.0115 0.0337 0.0324
Onchocerca volvulus Peroxidase homolog 0.0052 0.0105 0.033
Echinococcus multilocularis g-protein coupled receptor 0.0061 0.0138 0.0174
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0202 0.0202
Brugia malayi Cytochrome P450 family protein 0.0038 0.0057 0.012
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0013 0.0017
Loa Loa (eye worm) RNA binding protein 0.0191 0.0616 0.1661
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0206 0.0669 0.243
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0016 0.002
Toxoplasma gondii thioredoxin reductase 0.1018 0.3643 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0044 0.0122
Onchocerca volvulus 0.0034 0.0041 0.0092
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0203 0.0524
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0057 0.0121
Schistosoma mansoni hypothetical protein 0.0104 0.0296 0.0374
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0123 0.0365 0.1001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0013 0.0037
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0776 0.2754 0.7561
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0203 0.0257
Loa Loa (eye worm) glutaminase 2 0.033 0.1124 0.306
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.003 0.0025 0.0059
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0091 0.0091
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0776 0.2754 1
Schistosoma mansoni neuropeptide receptor 0.0061 0.0138 0.0174
Schistosoma mansoni sodium/chloride dependent transporter 0.0161 0.0506 0.064
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0044 0.0122
Brugia malayi conserved hypotetical protein 0.003 0.0026 0.0034
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0138 0.0174
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0359 0.5361
Schistosoma mansoni neuropeptide receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.002 0.0025
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0067 0.0054
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0088 0.0111
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0275 0.0924 0.2509
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.003 0.0025 0.0089
Schistosoma mansoni hypothetical protein 0.0079 0.0203 0.0257
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2029 0.7339 0.7339
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0206 0.0669 0.1614
Loa Loa (eye worm) programmed cell death 8 0.0206 0.0669 0.1808
Loa Loa (eye worm) hypothetical protein 0.0034 0.0039 0.0071
Schistosoma mansoni rab6-interacting 0.013 0.0393 0.0497
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.003 0.0025 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.003 0.0025 0.0059
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0186 0.0597 0.0597
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0206 0.0669 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0091 0.0215
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0105 0.0253
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0206 0.0669 1
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0113 0.0328 0.1191
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.057 0.2001 0.5476
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0186 0.0597 0.0756
Schistosoma mansoni amine GPCR 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0045 0.008 0.0185
Schistosoma mansoni glutamate synthase 0.0206 0.0669 0.0848
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.003 0.0025 0.0089
Schistosoma mansoni disulfide oxidoreductase 0.0206 0.0669 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.003 0.007
Onchocerca volvulus Peroxidasin homolog 0.0052 0.0105 0.033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0148 0.0188
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0049 0.0139
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0206 0.0669 0.1838
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0123 0.0365 0.1291
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0061 0.0138 0.0343
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0036 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.003 0.0025 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0206 0.0669 0.0669
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0112 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.003 0.0025 0.0059
Echinococcus granulosus acetylcholinesterase 0.0376 0.1293 0.1639
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0337 0.0427
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0206 0.0669 0.2401
Schistosoma mansoni DNA helicase recq1 0.0028 0.002 0.0025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0196 0.293
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0337 0.119
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.003 0.0025 0.0089
Plasmodium vivax thioredoxin reductase, putative 0.1018 0.3643 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0206 0.0669 0.1807
Schistosoma mansoni hypothetical protein 0.017 0.0537 0.068
Entamoeba histolytica recQ family helicase, putative 0.0031 0.003 0.045
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0064 0.0148 0.0372
Schistosoma mansoni ap endonuclease 0.0077 0.0196 0.0248
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.0616 0.1661
Plasmodium falciparum thioredoxin reductase 0.1018 0.3643 1
Brugia malayi Pre-SET motif family protein 0.0096 0.0267 0.0697
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0121 0.0359 0.0865
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0091 0.1365
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0776 0.2754 0.349
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0924 0.3328
Brugia malayi Dopamine receptor 0.0061 0.0138 0.0342
Brugia malayi Carboxylesterase family protein 0.0064 0.0149 0.0373
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0057 0.0121
Brugia malayi Carboxylesterase family protein 0.0376 0.1293 0.3527
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0026 0.0034
Schistosoma mansoni opsin-like receptor 0.0061 0.0138 0.0174
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0091 0.0078
Trypanosoma brucei hypothetical protein, conserved 0.0206 0.0669 0.0669
Leishmania major cytochrome p450-like protein 0.0038 0.0057 0.0057
Schistosoma mansoni neuropeptide f receptor 76f 0.0061 0.0138 0.0174
Loa Loa (eye worm) solute carrier family 6 member 4 0.0161 0.0506 0.1357
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0172 0.0416
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.0993 0.0993
Onchocerca volvulus 0.0064 0.0149 0.0494
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0206 0.0669 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0115 0.0337 0.0324
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0036 0.0129
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0036 0.0091
Plasmodium vivax hypothetical protein, conserved 0.0028 0.002 0.0055
Schistosoma mansoni single-minded 0.0154 0.0481 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0046 0.0131
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1157 0.4148 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0019
Echinococcus multilocularis dro:myosuppressin receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0064 0.0148 0.0373
Echinococcus granulosus nuclear factor of activated T cells 5 0.0156 0.0487 0.0617
Onchocerca volvulus 0.0082 0.0215 0.074
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0061 0.0138 0.0174
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0068 0.0054
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0076
Echinococcus granulosus lysine specific demethylase 5A 0.01 0.0281 0.0356
Brugia malayi hypothetical protein 0.0038 0.0055 0.0113
Echinococcus granulosus neuropeptide receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0061 0.0138 0.0174
Onchocerca volvulus 0.0064 0.0149 0.0494
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0068 0.0211
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0017 0.0021
Brugia malayi bHLH-PAS transcription factor 0.0114 0.0334 0.0883
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0776 0.2754 0.7552
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0008
Onchocerca volvulus 0.0064 0.0149 0.0494
Loa Loa (eye worm) hypothetical protein 0.013 0.0393 0.1045
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0064 0.0149 0.0359
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0044 0.0659
Onchocerca volvulus 0.0761 0.2699 1
Schistosoma mansoni netrin receptor unc5 0.003 0.0027 0.0034
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0426 0.0426
Schistosoma mansoni hypothetical protein 0.0679 0.2402 0.3044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0064 0.0148 0.0373
Brugia malayi Serotonin receptor 0.0061 0.0138 0.0342
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0091 0.0091
Echinococcus multilocularis Polycystic kidney disease protein 0.013 0.0393 0.0497
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.003 0.0025 0.0089
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0036 0.0049 0.0035
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0013 0.0017
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0075 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0577 0.2065
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0061 0.0138 0.0174
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0359 0.0454
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.003 0.0025 0.0089
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0113 0.0328 0.0415
Echinococcus granulosus thioredoxin glutathione reductase 0.1019 0.3646 0.4621
Echinococcus multilocularis G-protein coupled receptor, putative 0.0061 0.0138 0.0174
Loa Loa (eye worm) blistered cuticle protein 3 0.0052 0.0105 0.0253
Echinococcus multilocularis allatostatin A receptor 0.0061 0.0138 0.0174
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.003 0.0025 0.0089
Schistosoma mansoni cytochrome P450 0.003 0.0025 0.0031
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0203 0.0523
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0138 0.0174
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0181 0.0464
Brugia malayi Cytochrome P450 family protein 0.0038 0.0057 0.012
Echinococcus multilocularis acetylcholinesterase 0.0376 0.1293 0.1639
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Onchocerca volvulus Chorion peroxidase homolog 0.0052 0.0105 0.033
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0206 0.0669 0.2401
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0044 0.0084
Trichomonas vaginalis set domain proteins, putative 0.076 0.2698 0.9794
Loa Loa (eye worm) hypothetical protein 0.0206 0.0669 0.1808
Echinococcus granulosus peregrin 0.0028 0.002 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0064 0.0148 0.0372
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0202 0.0556
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0013 0.0017
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0064 0.0149 0.0188
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0206 0.0669 0.2401
Schistosoma mansoni glutamate synthase 0.0206 0.0669 0.0848
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0064 0.0148 0.0373
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0061 0.0138 0.0453
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0109 0.0313 0.0396
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0203 0.0257
Echinococcus multilocularis thyroid hormone receptor alpha 0.0064 0.0148 0.0188
Onchocerca volvulus 0.0061 0.0138 0.0453
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0776 0.2754 0.2754
Echinococcus granulosus chromobox protein 1 0.0078 0.02 0.0253
Loa Loa (eye worm) hypothetical protein 0.0161 0.0506 0.1357
Brugia malayi hypothetical protein 0.003 0.0026 0.0034
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0202 0.0735
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0064 0.0149 0.0188
Toxoplasma gondii hypothetical protein 0.0047 0.009 0.0246
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0105 0.0253
Echinococcus multilocularis aryl hydrocarbon receptor 0.004 0.0063 0.0079
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis chromobox protein 1 0.0078 0.02 0.0253
Loa Loa (eye worm) glutathione reductase 0.1018 0.3643 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0046 0.0131
Loa Loa (eye worm) hypothetical protein 0.0502 0.1753 0.4794
Loa Loa (eye worm) hypothetical protein 0.0064 0.0149 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0055 0.0164
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0013 0.0017
Onchocerca volvulus 0.0061 0.0138 0.0453
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0026 0.0036
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1157 0.4148 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0061 0.0138 0.0174
Brugia malayi G-protein coupled receptor 0.0061 0.0138 0.0342
Plasmodium vivax amine transporter, putative 0.0027 0.0016 0.0044
Echinococcus granulosus tm gpcr rhodopsin 0.0944 0.3369 0.4269
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0206 0.0669 0.0848
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0064 0.0148 0.0188
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0138 0.0174
Schistosoma mansoni lipoxygenase 0.0503 0.1758 0.2228
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0026 0.0032
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0196 0.0712
Brugia malayi Thioredoxin reductase 0.1018 0.3643 1
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0138 0.0174
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0206 0.0669 0.1838
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0337 0.119
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0057 0.0206
Loa Loa (eye worm) hypothetical protein 0.0043 0.0075 0.0171
Mycobacterium leprae Conserved hypothetical protein 0.003 0.0025 0.0059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0138 0.0174
Echinococcus granulosus tar DNA binding protein 0.0191 0.0616 0.078
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0776 0.2754 0.2745
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.011 0.0319 0.0306
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0015 0.0019
Trypanosoma cruzi NADH dehydrogenase, putative 0.0206 0.0669 0.0657
Plasmodium falciparum glutathione reductase 0.1018 0.3643 1
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0029 0.0066
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0206 0.0669 0.1807
Schistosoma mansoni hypothetical protein 0.0061 0.0138 0.0174
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0121 0.0359 0.1303
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0587 0.2063 0.4974
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0091 0.0115
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0016 0.002
Brugia malayi hypothetical protein 0.013 0.0393 0.1044
Onchocerca volvulus 0.013 0.0393 0.1403
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0126 0.0377 0.0477
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0061 0.0138 0.0342
Onchocerca volvulus 0.0061 0.0138 0.0453
Brugia malayi hypothetical protein 0.0212 0.0693 0.1871
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0668 0.236 0.6466
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0016 0.002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0016 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0046 0.0131
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.003 0.0025 0.0059
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0048 0.0035
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0048 0.0035
Echinococcus granulosus neuropeptide s receptor 0.0061 0.0138 0.0174
Schistosoma mansoni rab6-interacting 0.013 0.0393 0.0497
Loa Loa (eye worm) hypothetical protein 0.017 0.0537 0.1442
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.003 0.0025 0.0089
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0104 0.0091
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0215 0.0272
Echinococcus multilocularis serotonin receptor 0.019 0.0613 0.0776
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.003 0.0025 0.0089
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0088 0.0206
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Schistosoma mansoni chromobox protein 0.0078 0.02 0.0253
Brugia malayi hypothetical protein 0.0034 0.0039 0.007
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0064 0.0148 0.0372
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Mycobacterium tuberculosis Probable reductase 0.0587 0.2063 0.4974
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0175 0.0558 0.1501
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0577 0.2065
Brugia malayi ecdysone receptor 0.003 0.0026 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0993 0.0981
Leishmania major protein kinase, putative 0.0047 0.0086 0.0086
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0215 0.0555
Mycobacterium leprae putative cytochrome p450 0.003 0.0025 0.0059
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.002 0.0001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0044 0.0659
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0061 0.0138 0.0174
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.004 0.0063 0.0063
Trichomonas vaginalis guanylate cyclase, putative 0.004 0.0063 0.019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0148 0.0188
Brugia malayi steroid hormone receptor 0.0064 0.0148 0.0372
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.011 0.0319 0.0319
Brugia malayi AKH receptor 0.0061 0.0138 0.0342
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0036 0.0091
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0138 0.0174
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0044 0.0122
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0924 0.3328
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.002 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis Ankyrin 0.0031 0.0028 0.0035
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0046 0.0127
Schistosoma mansoni amine GPCR 0.0061 0.0138 0.0174
Echinococcus granulosus acetylcholinesterase 0.0376 0.1293 0.1639
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0597 0.2166
Schistosoma mansoni lamin 0.0057 0.0125 0.0158
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0202 0.0735
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0115 0.0337 0.0427
Loa Loa (eye worm) hypothetical protein 0.0393 0.1353 0.3691
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0206 0.0669 0.0848
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0044 0.0055
Toxoplasma gondii hypothetical protein 0.0027 0.0016 0.0044
Echinococcus multilocularis neuroligin 0.0064 0.0149 0.0188
Echinococcus granulosus neuroligin 0.0064 0.0149 0.0188
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0776 0.2754 1
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0319 0.1123
Echinococcus granulosus GPCR family 2 0.0079 0.0203 0.0257
Schistosoma mansoni lipoxygenase 0.0269 0.09 0.1141
Echinococcus granulosus neuropeptide receptor A26 0.0061 0.0138 0.0174
Echinococcus granulosus intermediate filament protein 0.0057 0.0125 0.0158
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0197 0.0636 0.1714
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0026 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0007
Loa Loa (eye worm) hypothetical protein 0.0064 0.0149 0.0374
Trichomonas vaginalis glutathione reductase, putative 0.0776 0.2754 1
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0125 0.0309
Echinococcus multilocularis neuropeptide FF receptor 2 0.0061 0.0138 0.0174
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0115 0.0337 0.0892
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0138 0.0174
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0115 0.0337 0.0427
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0493 0.1323
Brugia malayi nuclear hormone receptor 0.0064 0.0148 0.0372
Echinococcus granulosus Ankyrin 0.0031 0.0028 0.0035
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0091 0.0091
Toxoplasma gondii exonuclease III APE 0.0077 0.0196 0.0538
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0044 0.0122
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0776 0.2754 0.349
Schistosoma mansoni nuclear receptor 0.003 0.0026 0.0032
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.002 0.0018
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0091 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.003 0.0025 0.0059
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0202 0.0256
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0503 0.1758 0.2228
Brugia malayi Melatonin receptor type 1A 0.0061 0.0138 0.0342
Brugia malayi putative neuropeptide receptor 0.0061 0.0138 0.0342
Onchocerca volvulus 0.0052 0.0105 0.033
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0138 0.0174
Echinococcus granulosus para nitrobenzyl esterase 0.0064 0.0149 0.0188
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0087 0.0279
Echinococcus granulosus glutamate synthase 0.0206 0.0669 0.0848
Loa Loa (eye worm) hypothetical protein 0.003 0.0027 0.004
Trichomonas vaginalis spcc417.12 protein, putative 0.0064 0.0149 0.0504
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0138 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.003 0.0025 0.0059
Toxoplasma gondii NADPH-glutathione reductase 0.0776 0.2754 0.7561
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0924 0.3328
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0028 0.0041
Mycobacterium ulcerans hypothetical protein 0.0206 0.0669 0.243
Echinococcus granulosus BC026374 protein S09 family 0.0064 0.0149 0.0188
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0181 0.0168
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0007
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0016 0.002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0064 0.0148 0.0493
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0113 0.0328 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0055 0.0164
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0064 0.0148 0.0188
Brugia malayi hypothetical protein 0.0064 0.0149 0.0373
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.002 0.0025
Trichomonas vaginalis guanylate cyclase, putative 0.004 0.0063 0.019
Brugia malayi MH2 domain containing protein 0.0239 0.0789 0.2136
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0776 0.2754 0.664
Echinococcus multilocularis musashi 0.0057 0.0125 0.0158
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0206 0.0669 0.1614
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0776 0.2754 0.7561
Loa Loa (eye worm) hypothetical protein 0.0201 0.065 0.1756
Brugia malayi Dopamine receptor protein 2 0.0061 0.0138 0.0342
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0206 0.0669 0.0848
Brugia malayi Calcitonin receptor-like protein seb-1 0.0248 0.0824 0.2233
Plasmodium falciparum thioredoxin reductase 0.0776 0.2754 0.7561
Echinococcus multilocularis serotonin receptor 0.019 0.0613 0.0776
Loa Loa (eye worm) hypothetical protein 0.0376 0.1293 0.3527
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0026 0.0034
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Trypanosoma cruzi trypanothione reductase, putative 0.1018 0.3643 0.3634
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0013 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Schistosoma mansoni peroxidasin 0.0052 0.0105 0.0132
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0267 0.0732
Echinococcus granulosus microtubule associated protein 2 0.2179 0.7891 1
Brugia malayi jmjC domain containing protein 0.01 0.0281 0.0739
Schistosoma mansoni jun-related protein 0.022 0.072 0.0912
Brugia malayi hypothetical protein 0.0136 0.0412 0.1098
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0393 0.1353 0.1341
Schistosoma mansoni hypothetical protein 0.0028 0.002 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0078 0.02 0.069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Loa Loa (eye worm) serotonin transporter b 0.0161 0.0506 0.1357
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Onchocerca volvulus Protein ultraspiracle homolog 0.0064 0.0148 0.0493
Echinococcus multilocularis survival motor neuron protein 1 0.0509 0.1778 0.2253
Echinococcus multilocularis para nitrobenzyl esterase 0.0064 0.0149 0.0188
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0776 0.2754 0.7561
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0115 0.0337 0.0337
Plasmodium falciparum phd finger protein, putative 0.0028 0.002 0.0055
Echinococcus granulosus hypothetical protein 0.0796 0.283 0.3587
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.003 0.0025 0.0089
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0061 0.0138 0.0174
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0206 0.0669 0.1838
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0196 0.0503
Brugia malayi G-protein coupled receptor 0.0061 0.0138 0.0342
Trichomonas vaginalis glutamate synthase, putative 0.0206 0.0669 0.2401
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0359 0.0454
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.004 0.0063 0.0049
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.003 0.0071
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni intermediate filament proteins 0.0057 0.0125 0.0158
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0138 0.0343
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0039 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0337 0.119
Brugia malayi 6-phosphofructokinase 0.0121 0.0359 0.0953
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0248 0.0824 0.2233
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0196 0.0676
Schistosoma mansoni hypothetical protein 0.022 0.072 0.0912
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0776 0.2754 0.2754
Mycobacterium leprae Possible regulatory protein 0.004 0.0063 0.0151
Loa Loa (eye worm) hypothetical protein 0.0064 0.0149 0.0374
Loa Loa (eye worm) hypothetical protein 0.0034 0.0039 0.0071
Echinococcus granulosus 7TM GPCR rhodopsin 0.0061 0.0138 0.0174
Loa Loa (eye worm) carboxylesterase 0.0376 0.1293 0.3527
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0196 0.0473
Echinococcus granulosus neuropeptide FF receptor 2 0.0061 0.0138 0.0174
Plasmodium falciparum LCCL domain-containing protein 0.013 0.0393 0.1078
Echinococcus multilocularis BC026374 protein (S09 family) 0.0064 0.0149 0.0188
Schistosoma mansoni loxhd1 0.013 0.0393 0.0497
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0087 0.0279
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0206 0.0669 0.0848
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.002 0.0025
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0061 0.0076
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.003 0.0025 0.0089
Toxoplasma gondii aldehyde dehydrogenase 0.0186 0.0597 0.1638
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.005 0.0099 0.0236
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0359 0.0359
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.002 0.0055
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.0789 0.2137
Echinococcus granulosus transcription factor Dp 1 0.0042 0.007 0.0088
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Echinococcus multilocularis chromobox protein 1 0.0078 0.02 0.0253
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0181 0.0181
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0587 0.2063 0.4974
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0026 0.0035
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0776 0.2754 0.2745
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0013 0.0017
Schistosoma mansoni sulfide quinone reductase 0.0206 0.0669 0.0848
Schistosoma mansoni microtubule-associated protein tau 0.2179 0.7891 1
Echinococcus granulosus jumonji domain containing protein 0.004 0.0061 0.0076
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0104 0.0286
Schistosoma mansoni nuclear hormone receptor 0.003 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Brugia malayi nuclear hormone receptor 0.003 0.0026 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0036 0.0129
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0036 0.0098
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0008
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0068 0.0211
Loa Loa (eye worm) thioredoxin reductase 0.1018 0.3643 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0016 0.002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0597 0.2166
Echinococcus multilocularis orexin receptor type 2 0.0061 0.0138 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0064 0.0148 0.0372
Loa Loa (eye worm) hypothetical protein 0.0096 0.0267 0.0698
Plasmodium falciparum ferrodoxin reductase-like protein 0.0206 0.0669 0.1838
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0061 0.0138 0.0174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2029 0.7339 0.7336
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2029 0.7339 0.7339
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Loa Loa (eye worm) hypoxia-induced factor 1 0.0478 0.1664 0.4548
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0036 0.0048 0.006
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0197 0.0636 0.1532
Plasmodium vivax SET domain protein, putative 0.0096 0.0267 0.0732
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0026 0.0034
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0159 0.0496 0.0628
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0044 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0337 0.119
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.0597 0.0756
Onchocerca volvulus 0.0057 0.0125 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.019
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0026 0.0032
Echinococcus multilocularis GPCR, family 2 0.0079 0.0203 0.0257
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0036 0.0091
Echinococcus granulosus serotonin receptor 0.0061 0.0138 0.0174
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0036 0.0098
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0393 0.1353 0.3691
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0044 0.0085
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0056 0.0042
Echinococcus multilocularis ecdysone induced protein 78C 0.0064 0.0148 0.0188
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.003 0.0025 0.0089
Leishmania major hypothetical protein, conserved 0.0027 0.0013 0.0013
Echinococcus multilocularis neuropeptide s receptor 0.0061 0.0138 0.0174
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0055 0.0069
Loa Loa (eye worm) hypothetical protein 0.0263 0.0878 0.2382
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0359 0.5361
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0088 0.0207
Loa Loa (eye worm) hepatopoietin HPO2 0.0036 0.0048 0.0097
Brugia malayi Cytochrome P450 family protein 0.003 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0027 0.0016 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.232 0.8406 0.8404
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Loa Loa (eye worm) TAR-binding protein 0.0191 0.0616 0.1661
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0206 0.0669 0.0669
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.003 0.0025 0.0089
Leishmania major hypothetical protein, conserved 0.0036 0.0048 0.0048
Brugia malayi G protein-coupled receptor F59B2.13 0.0061 0.0138 0.0342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Onchocerca volvulus 0.0061 0.0138 0.0453
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0061 0.0138 0.0174
Mycobacterium ulcerans hypothetical protein 0.0155 0.0483 0.1755
Loa Loa (eye worm) animal heme peroxidase 0.0052 0.0105 0.0253
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.003 0.0017
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0064 0.0148 0.0188
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0121 0.0359 0.0865
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0267 0.0337
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0215 0.0272
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0113 0.0328 0.1191
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0267 0.0337
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.004 0.0063 0.019
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0016 0.002
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0206 0.0669 0.2375
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni biogenic amine (5HT) receptor 0.019 0.0613 0.0776
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0197 0.0636 0.0636
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0138 0.0174
Echinococcus multilocularis jun protein 0.027 0.0905 0.1146
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0148 0.0188
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0113 0.0328 0.0415
Onchocerca volvulus 0.0061 0.0138 0.0453
Echinococcus granulosus sodium channel protein 0.0126 0.0377 0.0477
Schistosoma mansoni hypothetical protein 0.0079 0.0203 0.0257
Entamoeba histolytica hypothetical protein 0.0038 0.0055 0.0815
Loa Loa (eye worm) hypothetical protein 0.0066 0.0158 0.04
Echinococcus multilocularis transfer RNA-Lys 0.0114 0.0334 0.0423
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0123 0.0365 0.1291
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0088 0.0111
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0036 0.0129
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.003 0.0025 0.0089
Echinococcus multilocularis tar DNA binding protein 0.0191 0.0616 0.078
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0196 0.0248
Loa Loa (eye worm) carboxylesterase 0.0064 0.0149 0.0374
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0577 0.2065
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0064 0.0148 0.0188
Onchocerca volvulus 0.0052 0.0105 0.033
Leishmania major hypothetical protein, conserved 0.0206 0.0669 0.0669
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0039 0.0049
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0013 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0016 0.002
Brugia malayi tailless protein 0.003 0.0026 0.0034
Brugia malayi sulfakinin receptor protein 0.0061 0.0138 0.0342
Loa Loa (eye worm) hypothetical protein 0.0518 0.1811 0.4952
Brugia malayi TAR-binding protein 0.0191 0.0616 0.166
Onchocerca volvulus 0.0061 0.0138 0.0453
Schistosoma mansoni thyroid hormone receptor 0.0064 0.0148 0.0188
Schistosoma mansoni gliotactin 0.0064 0.0149 0.0188
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0206 0.0669 0.1838
Schistosoma mansoni inositol monophosphatase 0.0078 0.0202 0.0256
Echinococcus granulosus mitogen activated protein kinase 3 0.011 0.0319 0.0403
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0181 0.2711
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0026 0.0035
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.003 0.0025 0.0089
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0027 0.0016 0.002
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0026 0.0032
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0206 0.0669 0.0848
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0776 0.2754 0.349
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0138 0.0174
Schistosoma mansoni biogenic amine receptor 0.0061 0.0138 0.0174
Schistosoma mansoni jumonji/arid domain-containing protein 0.01 0.0281 0.0356
Brugia malayi Bromodomain containing protein 0.0028 0.002 0.0018
Trichomonas vaginalis apoptosis inducing factor, putative 0.0206 0.0669 0.2401
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0202 0.0189
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1157 0.4148 1
Treponema pallidum NADH oxidase 0.0776 0.2754 1
Trypanosoma cruzi trypanothione reductase, putative 0.0776 0.2754 0.2745
Echinococcus granulosus ecdysone induced protein 78C 0.0064 0.0148 0.0188
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0206 0.0669 0.0657
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0039 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0021 0.0037
Schistosoma mansoni polycystin 1-related 0.013 0.0393 0.0497
Echinococcus granulosus Polycystic kidney disease protein 0.013 0.0393 0.0497
Brugia malayi 6-phosphofructokinase 0.0121 0.0359 0.0952
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0203 0.0257
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0001
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0027 0.0016 0.002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0319 0.0306
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0088 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0064 0.0148 0.0372
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0013 0.0001
Onchocerca volvulus Dual oxidase homolog 0.0052 0.0105 0.033
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0206 0.0669 0.0657
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0061 0.0138 0.0342
Echinococcus multilocularis sex peptide receptor 0.0061 0.0138 0.0174
Mycobacterium tuberculosis Carboxylesterase LipT 0.0064 0.0149 0.0359
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0206 0.0669 0.0848
Schistosoma mansoni opsin-like receptor 0.0061 0.0138 0.0174
Brugia malayi Dopamine receptor protein 1 0.0061 0.0138 0.0342
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0088 0.0111
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0196 0.0644
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0206 0.0669 0.0848
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0064 0.0148 0.0188
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0041 0.0068 0.0054
Schistosoma mansoni jumonji/arid domain-containing protein 0.01 0.0281 0.0356
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0206 0.0669 0.0848
Onchocerca volvulus 0.013 0.0393 0.1403
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0206 0.0669 1
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0206 0.0669 0.243
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0587 0.2063 0.4974
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0048 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0064 0.0148 0.0372
Onchocerca volvulus 0.0091 0.025 0.0872
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.232 0.8406 0.8406
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0048 0.0132
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0126 0.0422
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0064 0.0148 0.0372
Schistosoma mansoni alpha glucosidase 0.0035 0.0044 0.0055
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0267 0.0337
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0206 0.0669 0.0848
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0055 0.0069
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0061 0.0138 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.003 0.0025 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0359 0.1269
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.0669 0.0657
Entamoeba histolytica hypothetical protein 0.0038 0.0055 0.0815
Echinococcus granulosus neuropeptide receptor 0.0061 0.0138 0.0174
Brugia malayi hypothetical protein 0.0051 0.0104 0.025
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0026 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0055 0.0164
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0104 0.0286
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0036 0.0098
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.0993 0.0993
Onchocerca volvulus Alhambra homolog 0.0028 0.002 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0021 0.0037
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0138 0.0343
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.003 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0924 0.3328
Mycobacterium ulcerans ferredoxin reductase 0.0206 0.0669 0.243
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0019
Schistosoma mansoni inositol monophosphatase 0.0078 0.0202 0.0256
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0993 0.0981
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0044 0.0122
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0138 0.0174
Brugia malayi photoreceptor-specific nuclear receptor 0.0064 0.0148 0.0372
Brugia malayi larval opioid receptor 0.0061 0.0138 0.0342
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0036 0.0098
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0044 0.0122
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0057 0.0121
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0091 0.0091
Brugia malayi Cytochrome P450 family protein 0.0049 0.0095 0.0224
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0202 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0613 0.2195
Echinococcus granulosus FTZ F1 alpha 0.0064 0.0148 0.0188
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0138 0.0174
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0376 0.1293 0.1639
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.002 0.0055
Echinococcus multilocularis peroxidasin 0.0052 0.0105 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2756 1 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0056 0.0056
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0016 0.0008
Schistosoma mansoni biogenic amine receptor 0.0061 0.0138 0.0174
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0202 0.3023
Loa Loa (eye worm) hypothetical protein 0.0161 0.0506 0.1357
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0206 0.0669 0.1614
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0206 0.0669 0.1838
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.003 0.0025 0.0089
Loa Loa (eye worm) norepinephrine transporter 0.0161 0.0506 0.1357
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0061 0.0138 0.0342
Onchocerca volvulus 0.0206 0.0669 0.2435
Brugia malayi RNA binding protein 0.0191 0.0616 0.166
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0013 0.0017
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0138 0.0174
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0027 0.0039
Mycobacterium ulcerans 6-phosphofructokinase 0.0121 0.0359 0.1303
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0206 0.0669 0.243
Schistosoma mansoni sodium-dependent amino acid transporter 0.0027 0.0016 0.002
Schistosoma mansoni zinc finger protein 0.003 0.0026 0.0032
Trypanosoma brucei C-8 sterol isomerase, putative 0.0393 0.1353 0.1353
Schistosoma mansoni biogenic amine receptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.013 0.0393 0.1045
Leishmania major protein kinase, putative 0.0041 0.0068 0.0068
Leishmania major NADH dehydrogenase, putative 0.0206 0.0669 0.0669
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2756 1 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.011 0.0319 0.0403
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.0669 0.0657
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0197 0.0636 0.0805
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0104 0.0286
Schistosoma mansoni nuclear hormone receptor 0.003 0.0026 0.0032
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.011 0.0319 0.0319
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0021 0.0026
Echinococcus granulosus peptide allatostatin:somatostatin 0.0061 0.0138 0.0174
Plasmodium falciparum amino acid transporter, putative 0.0027 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0206 0.0669 0.243
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0138 0.0174
Brugia malayi Animal haem peroxidase family protein 0.0052 0.0105 0.0252
Treponema pallidum sodium- and chloride- dependent transporter 0.0161 0.0506 0.1836
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.0027 0.0034
Brugia malayi G protein-coupled receptor 0.0061 0.0138 0.0342
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.003 0.0025 0.0089
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0359 0.1269
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0013 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0148 0.0372
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0036 0.0091
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0113 0.0328 0.0328
Loa Loa (eye worm) inositol-1 0.0078 0.0202 0.0522
Giardia lamblia Thioredoxin reductase 0.0206 0.0669 0.2375
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0126 0.0377 0.0377
Leishmania major cytochrome p450-like protein 0.003 0.0025 0.0025
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0068 0.0086
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.003 0.0025 0.0089
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0215 0.0272
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0203 0.0523
Schistosoma mansoni jumonji domain containing protein 0.0139 0.0426 0.054
Schistosoma mansoni survival motor neuron protein 0.0104 0.0296 0.0374
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0064 0.0149 0.0504
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0924 0.3328
Brugia malayi neuropeptide F receptor 0.0061 0.0138 0.0342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0035
Echinococcus multilocularis sodium channel protein 0.0126 0.0377 0.0477
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.003 0.0025 0.0089
Schistosoma mansoni ap endonuclease 0.0077 0.0196 0.0248
Onchocerca volvulus 0.0061 0.0138 0.0453
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0016 0.002
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0172 0.0416
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0206 0.0669 0.1614
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0026 0.0034
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0044 0.0122
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0359 0.0953
Brugia malayi Uncoordinated protein 44 0.003 0.0027 0.0039
Schistosoma mansoni growth hormone secretagogue receptor 0.0061 0.0138 0.0174
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0577 0.2065
Schistosoma mansoni adenoreceptor 0.0061 0.0138 0.0174
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0138 0.0343
Brugia malayi Doublecortin family protein 0.013 0.0393 0.1044
Loa Loa (eye worm) hypothetical protein 0.0056 0.0121 0.0298
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.002 0.0025
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0196 0.0538
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0061 0.0138 0.0343
Schistosoma mansoni aryl hydrocarbon receptor 0.0154 0.0481 0.0609
Brugia malayi hypothetical protein 0.0061 0.0138 0.0342
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0057 0.0043
Loa Loa (eye worm) hypothetical protein 0.019 0.0613 0.1652
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0181 0.0229
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1018 0.3643 0.8782
Entamoeba histolytica serine/threonine protein kinase, putative 0.0115 0.0337 0.5034
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0138 0.0174
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0048 0.0048
Brugia malayi ORL1-like opioid receptor 0.0061 0.0138 0.0342
Mycobacterium ulcerans glutaminase 0.033 0.1124 0.408
Echinococcus multilocularis peregrin 0.0028 0.002 0.0025
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0206 0.0669 0.1614
Loa Loa (eye worm) hypothetical protein 0.0064 0.0148 0.0373
Onchocerca volvulus 0.003 0.0026 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0026 0.0032
Trypanosoma cruzi cytochrome p450-like protein, putative 0.003 0.0025 0.0011
Schistosoma mansoni amine GPCR 0.0061 0.0138 0.0174
Loa Loa (eye worm) hypothetical protein 0.0052 0.0105 0.0253
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni hypothetical protein 0.0106 0.0303 0.0383
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0138 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0064 0.0148 0.0372
Echinococcus granulosus RUN 0.013 0.0393 0.0497
Brugia malayi hypothetical protein 0.0027 0.0016 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.002 0.0034
Brugia malayi Nuclear hormone receptor E75 0.003 0.0026 0.0034
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0091 0.0115
Mycobacterium tuberculosis Probable oxidoreductase 0.1157 0.4148 1
Echinococcus multilocularis 0.003 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0034 0.0039 0.0071
Echinococcus multilocularis acetylcholinesterase 0.0376 0.1293 0.1639
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0156 0.0487 0.0617
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0138 0.0174
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0483 0.1165
Mycobacterium ulcerans dehydrogenase 0.0206 0.0669 0.243
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0013 0.0017
Brugia malayi follicle stimulating hormone receptor 0.0061 0.0138 0.0342
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0202 0.0256
Onchocerca volvulus 0.0061 0.0138 0.0453
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0206 0.0669 0.243
Trypanosoma brucei protein kinase, putative 0.011 0.0319 0.0319
Onchocerca volvulus Peroxidase homolog 0.0052 0.0105 0.033
Leishmania major cytochrome p450-like protein 0.003 0.0025 0.0025
Entamoeba histolytica hypothetical protein 0.0038 0.0055 0.0815
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0125 0.0308
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0206 0.0669 0.2401
Plasmodium vivax JmjC domain containing protein 0.0027 0.0013 0.0037
Schistosoma mansoni kinase 0.0059 0.0132 0.0166
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0039 0.0049
Echinococcus multilocularis neuropeptide receptor A26 0.0061 0.0138 0.0174
Schistosoma mansoni hypothetical protein 0.003 0.0025 0.0031
Echinococcus multilocularis FTZ F1 alpha 0.0064 0.0148 0.0188
Schistosoma mansoni thyroid hormone receptor 0.0064 0.0148 0.0188
Brugia malayi Heterochromatin protein 1 0.0078 0.02 0.0514
Loa Loa (eye worm) hypothetical protein 0.0051 0.0104 0.0251
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0343
Schistosoma mansoni hypothetical protein 0.003 0.0027 0.0034
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0196 0.0712
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.002 0.0055
Schistosoma mansoni alpha-1 adrenergic receptor 0.0061 0.0138 0.0174
Brugia malayi latrophilin 2 splice variant baaae 0.017 0.0537 0.1442
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0064 0.0148 0.0372
Mycobacterium ulcerans glutamate synthase subunit beta 0.0206 0.0669 0.243
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0064 0.0148 0.0372
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0028 0.004

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 11.9 uM PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) > 80 uM PUBCHEM_BIOASSAY: Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) > 80 uM PUBCHEM_BIOASSAY: Dose Response orthogonal assay utilizing the direct end-point detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) > 80 uM PUBCHEM_BIOASSAY: Dose Response orthogonal kinetic assay utilizing the direct detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696] ChEMBL. No reference
IC50 (functional) 133.66 uM PubChem BioAssay. Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Primary and Confirmatory Screens. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.5012 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.631 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 0.631 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 1.7783 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.0546 uM PUBCHEM_BIOASSAY: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540272] ChEMBL. No reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.9811 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 5.3233 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.4927 uM PUBCHEM_BIOASSAY: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation in HepG2 cytotox. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540272] ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Giardia lamblia
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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