Detailed information for compound 155094

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 616.63 | Formula: C34H31F3N4O4
  • H donors: 3 H acceptors: 3 LogP: 6.44 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C(F)(F)F.C[C@H](c1ccccc1)NC(=O)c1cc2c(n1Cc1cccc(c1)C(=N)N)ccc(c2)OCc1ccccc1
  • InChi: 1S/C32H30N4O2.C2HF3O2/c1-22(25-12-6-3-7-13-25)35-32(37)30-19-27-18-28(38-21-23-9-4-2-5-10-23)15-16-29(27)36(30)20-24-11-8-14-26(17-24)31(33)34;3-2(4,5)1(6)7/h2-19,22H,20-21H2,1H3,(H3,33,34)(H,35,37);(H,6,7)/t22-;/m1./s1
  • InChiKey: RBLPAYZSBANSDW-VZYDHVRKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor X Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0021 0.0156 0.0109
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0108 0.2017 0.1979
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis ubiquitin specific protease 41 0.0021 0.0156 0.0109
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.0142 0.0096
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.2781
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0047
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.0142 0.0096
Brugia malayi RNA binding protein 0.014 0.2719 0.2719
Brugia malayi Smad1 0.0025 0.0242 0.0242
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0021 0.0156 0.0109
Schistosoma mansoni tar DNA-binding protein 0.014 0.2719 0.2685
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Onchocerca volvulus Serine\/threonine kinase homolog 0.0108 0.2017 0.528
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0332 0.1268
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0021 0.0156 0.0109
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Schistosoma mansoni smad1 5 8 and 0.0025 0.0242 0.0196
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0479 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0847 0.3758
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0242 0.0196
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0021 0.0156 0.0109
Loa Loa (eye worm) MH2 domain-containing protein 0.037 0.7662 0.7662
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0021 0.0142 0.0142
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0047
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0847 0.3758
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.2017 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0156 0.0109
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Plasmodium falciparum ubiquitin specific protease, putative 0.0021 0.0156 0.2781
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0088 0.0088
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0047
Leishmania major hypothetical protein, conserved 0.0029 0.0332 0.1268
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0021 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Brugia malayi MH2 domain containing protein 0.037 0.7662 0.7662
Loa Loa (eye worm) RNA binding protein 0.014 0.2719 0.2719
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi MH1 domain containing protein 0.0025 0.0242 0.0242
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.0142 0.0142
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0156 0.0109
Brugia malayi N-terminal motif family protein 0.0189 0.3778 0.3778
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Onchocerca volvulus 0.0021 0.0156 0.0291
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.0142 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.0156 0.0109
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.0142 0.0096
Loa Loa (eye worm) transcription factor SMAD2 0.037 0.7662 0.7662
Schistosoma mansoni tar DNA-binding protein 0.014 0.2719 0.2685
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.2017 1
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0021 0.0156 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0479 1 1
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0021 0.0142 0.0096
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.2017 1
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.0156 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0021 0.0156 0.0109
Echinococcus multilocularis expressed protein 0.0021 0.0142 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0021 0.0156 0.0109
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0021 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0108 0.2017 0.1979
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0332 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Schistosoma mansoni peptidase 0.0022 0.0163 0.0116
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0021 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0021 0.0156 0.0109
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0479 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni smad 0.0025 0.0242 0.0196
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Loa Loa (eye worm) TAR-binding protein 0.014 0.2719 0.2719
Entamoeba histolytica serine/threonine protein kinase, putative 0.0108 0.2017 1
Schistosoma mansoni smad1 5 8 and 0.0025 0.0242 0.0196
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0021 0.0156 0.0109
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0156 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0332 1
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0021 0.0142 0.0096
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0088 0.1416
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.0142 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0021 0.0142 0.0096
Loa Loa (eye worm) hypothetical protein 0.0021 0.0142 0.0142
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Plasmodium falciparum ubiquitin specific protease, putative 0.0021 0.0156 0.2781
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0156 0.0109
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0242 0.0242
Schistosoma mansoni Smad4 0.0025 0.0242 0.0196
Loa Loa (eye worm) hypothetical protein 0.0021 0.0142 0.0142
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.2017 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.0142 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0021 0.0156 0.0109
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0332 0.0332
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0088 0.1416
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0021 0.0156 0.0109
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.0142 0.0142
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0156 0.0109
Giardia lamblia Kinase, PLK 0.0108 0.2017 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0021 0.0156 0.0109
Onchocerca volvulus 0.0021 0.0156 0.0291
Trypanosoma brucei polo-like protein kinase 0.0108 0.2017 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.0156 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.2017 1
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0332 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0021 0.0156 0.0109
Toxoplasma gondii ubiquitin-specific protease USP4 0.0021 0.0156 0.3803
Entamoeba histolytica hypothetical protein 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0021 0.0156 0.0109
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.0142 0.0096
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0088 0.0088
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0021 0.0156 0.2781
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0156 0.0109
Echinococcus granulosus ubiquitin specific peptidase c family 0.0021 0.0156 0.0109
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0242 0.0196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.0156 0.007
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Echinococcus multilocularis Smad4 0.0025 0.0242 0.0196
Echinococcus granulosus expressed protein 0.0021 0.0142 0.0096
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.014 0.2719 0.2719
Brugia malayi MH2 domain containing protein 0.0025 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0021 0.0142 0.0142
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0156 0.007
Brugia malayi MH2 domain containing protein 0.0025 0.0242 0.0242
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.2781
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi hypothetical protein 0.0029 0.0332 0.0332
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0021 0.0156 0.0109
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0088 0.0041
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.0142 0.0096
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0156 0.007
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0047 0.0047
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.2781
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.0156 0.2781
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Brugia malayi MH1 domain containing protein 0.0025 0.0242 0.0242
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0242 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.2017 1
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0021 0.0142 0.0142
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0021 0.0156 0.0109
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0021 0.0156 0.0109
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0021 0.0156 0.0109
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.0156 0.007
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.0142 0.0096
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0088 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0142 0.0142
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0021 0.0156 0.0109
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0156 0.0109
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus tar DNA binding protein 0.014 0.2719 0.2685
Schistosoma mansoni smad1 5 8 and 0.0025 0.0242 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.2017 0.1979
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0021 0.0156 0.2781
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0021 0.0156 0.0109
Brugia malayi Fibulin-1 precursor 0.0016 0.0047 0.0047
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0021 0.0156 0.0109
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.2017 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0242 0.0196
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0021 0.0156 0.0109
Schistosoma mansoni tar DNA-binding protein 0.014 0.2719 0.2685
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.0142 0.0096
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0332 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0021 0.0156 0.0109
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Loa Loa (eye worm) hypothetical protein 0.0021 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Plasmodium vivax ubiquitin specific protease, putative 0.0021 0.0156 0.2781
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.3803
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0479 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0021 0.0156 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Echinococcus granulosus ubiquitin specific protease 41 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0021 0.0142 0.0142
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.0142 0.0096
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Brugia malayi isocitrate dehydrogenase 0.0018 0.0088 0.0088
Schistosoma mansoni tar DNA-binding protein 0.014 0.2719 0.2685
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.0142 0.0096
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0021 0.0156 0.0109
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0021 0.0156 0.0109
Onchocerca volvulus 0.0021 0.0156 0.0291
Onchocerca volvulus 0.0021 0.0142 0.0255
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0156 0.0109
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0156 0.2781
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0479 1 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0021 0.0156 0.2781
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.0142 0.0096
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0088 0.5
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0021 0.0142 0.0142
Brugia malayi RNA recognition motif domain containing protein 0.014 0.2719 0.2719
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.0156 0.0109
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi hypothetical protein 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0332 0.1268
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi G-protein alpha subunit 0.0021 0.0142 0.0142
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.0142 0.0096
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0021 0.0156 0.3803
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.0156 0.2781
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Onchocerca volvulus 0.0021 0.0142 0.0255
Echinococcus granulosus smad 0.0025 0.0242 0.0196
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0021 0.0142 0.0096
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.0142 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Toxoplasma gondii hypothetical protein 0.0021 0.0156 0.3803
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.0142 0.0096
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.0156 0.2781
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0156 0.0109
Echinococcus multilocularis expressed protein 0.0021 0.0156 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0021 0.0142 0.0142
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0479 1 1
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Onchocerca volvulus 0.0021 0.0142 0.0255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.0142 0.0096
Brugia malayi serine/threonine-protein kinase plk-2 0.0108 0.2017 0.2017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0021 0.0156 0.0109
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0108 0.2017 1
Echinococcus multilocularis tar DNA binding protein 0.014 0.2719 0.2685
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0021 0.0156 0.3803
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus Smad4 0.0025 0.0242 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.2017 1
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0021 0.0156 0.0156
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.0142 0.0096
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0156 0.0109
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0021 0.0156 0.0156
Echinococcus multilocularis smad 0.0025 0.0242 0.0196
Schistosoma mansoni hypothetical protein 0.0021 0.0156 0.0109
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0479 1 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0016 0.0047 0.0047
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.0156 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.2017 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0021 0.0156 0.0109
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0242 0.0242
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0189 0.3778 0.3778
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0021 0.0156 0.2781
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0332 0.1268
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0021 0.0156 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0088 0.0041
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0156 0.0353
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0021 0.0156 0.0109
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0021 0.0142 0.0142
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0479 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Brugia malayi TAR-binding protein 0.014 0.2719 0.2719
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0021 0.0156 0.0109
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.0142 0.0096
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.2781
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0016 0.0047 0.0047
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0021 0.0156 0.0109
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Brugia malayi hypothetical protein 0.0021 0.0142 0.0142
Brugia malayi hypothetical protein 0.0019 0.0108 0.0108
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.0156 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Schistosoma mansoni tar DNA-binding protein 0.014 0.2719 0.2685
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Loa Loa (eye worm) G protein alpha subunit 3 0.0021 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.0156 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0088 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0156 0.0156
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0242 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Brugia malayi ubiquitin specific protease 14 0.0021 0.0156 0.0156
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0156 0.0109
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0088 0.0041
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0088 0.0041
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0021 0.0156 0.0109
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0156 0.0156
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0021 0.0156 0.3803
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0088 0.0041
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.0156 0.2781
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0108 0.2017 0.2017
Schistosoma mansoni kinase 0.0055 0.0878 0.0834
Loa Loa (eye worm) Smad1 0.0025 0.0242 0.0242
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0189 0.3778 1
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.0156 0.2781
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0156 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.0156 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0156 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0021 0.0156 0.0109
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0156 0.007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0156 0.0353
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0156 0.0156
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0021 0.0142 0.0142

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 3690 nM Inhibition of Coagulation factor Xa ChEMBL. 12061878
Ki (binding) = 3690 nM Inhibition of Coagulation factor Xa ChEMBL. 12061878

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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