Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aldo keto reductase | 0.0094 | 0.7037 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Onchocerca volvulus | 0.0094 | 0.7037 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0066 | 0.3472 | 0.363 |
Echinococcus granulosus | aldo keto reductase | 0.0094 | 0.7037 | 1 |
Trypanosoma brucei | RNA helicase, putative | 0.0116 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0094 | 0.7037 | 0.6981 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0094 | 0.7037 | 1 |
Giardia lamblia | Aldose reductase | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0094 | 0.7037 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0094 | 0.7037 | 0.6981 |
Leishmania major | aldo-keto reductase-like protein | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0094 | 0.7037 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0094 | 0.7037 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0094 | 0.7037 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0094 | 0.7037 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.7037 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0094 | 0.7037 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0094 | 0.7037 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0094 | 0.7037 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Onchocerca volvulus | 0.0094 | 0.7037 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0094 | 0.7037 | 1 |
Onchocerca volvulus | 0.0094 | 0.7037 | 1 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Brugia malayi | bZIP transcription factor family protein | 0.0051 | 0.1441 | 0.2048 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0094 | 0.7037 | 1 |
Onchocerca volvulus | 0.0094 | 0.7037 | 1 | |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0094 | 0.7037 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0094 | 0.7037 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Onchocerca volvulus | 0.0094 | 0.7037 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0094 | 0.7037 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0094 | 0.7037 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0094 | 0.7037 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0094 | 0.7037 | 0.6981 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0094 | 0.7037 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0094 | 0.7037 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0066 | 0.3472 | 0.363 |
Loa Loa (eye worm) | oxidoreductase | 0.0094 | 0.7037 | 1 |
Giardia lamblia | Aldose reductase | 0.0094 | 0.7037 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0094 | 0.7037 | 1 |
Onchocerca volvulus | 0.0094 | 0.7037 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.