Detailed information for compound 1551297

Basic information

Technical information
  • TDR Targets ID: 1551297
  • Name: N-[(2S)-1-(4,5-dihydro-1,3-thiazol-2-ylamino) -3-methyl-1-oxobutan-2-yl]-3,5-dimethoxybenza mide
  • MW: 365.447 | Formula: C17H23N3O4S
  • H donors: 2 H acceptors: 2 LogP: 2.26 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)cc(c1)C(=O)N[C@H](C(=O)NC1=NCCS1)C(C)C
  • InChi: 1S/C17H23N3O4S/c1-10(2)14(16(22)20-17-18-5-6-25-17)19-15(21)11-7-12(23-3)9-13(8-11)24-4/h7-10,14H,5-6H2,1-4H3,(H,19,21)(H,18,20,22)/t14-/m0/s1
  • InChiKey: ZOWLWIJXWKUDAJ-AWEZNQCLSA-N  

Network

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Synonyms

  • N-[(1S)-1-(4,5-dihydrothiazol-2-ylcarbamoyl)-2-methyl-propyl]-3,5-dimethoxy-benzamide
  • N-[(1S)-1-[(4,5-dihydrothiazol-2-ylamino)-oxomethyl]-2-methylpropyl]-3,5-dimethoxybenzamide
  • N-[(2S)-1-(4,5-dihydro-1,3-thiazol-2-ylamino)-3-methyl-1-oxo-butan-2-yl]-3,5-dimethoxy-benzamide
  • T5252869
  • ZINC02661064

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0039 0.0038 0.0056
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Giardia lamblia Proteasome subunit beta type 3 0.0242 0.3179 0.4658
Brugia malayi 26S protease regulatory subunit 6A 0.0041 0.0074 0.0053
Brugia malayi proteasome subunit beta type 1 0.0294 0.3994 0.3981
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0191 0.2393 0.5
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0262 0.3498 0.5109
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0075 0.06 0.0879
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0037 0.0021 0.0031
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0037 0.0021 0.0031
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0063 0.0416 0.058
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0243 0.3206 0.3191
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.0039 0.0038 0.0056
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0631 0.9198 0.9197
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0063 0.0416 0.0416
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0063 0.0416 0.043
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0075 0.06 0.0879
Giardia lamblia 20S proteasome alpha subunit 2 0.0262 0.3498 0.5124
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0037 0.0021 0.0021
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0242 0.3179 0.4658
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.0039 0.0038 0.0056
Loa Loa (eye worm) proteasome subunit beta type 3 0.0242 0.3179 0.3456
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0347 0.4808 0.7035
Leishmania major proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0238 0.313 0.313
Trypanosoma cruzi 20S proteasome subunit 0.0242 0.3179 0.4658
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0242 0.3179 0.4641
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0041 0.0074 0.0077
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0294 0.3994 0.5839
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.007 0.0519 0.076
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0039 0.0038 0.0056
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0041 0.0072 0.0072
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0347 0.4808 0.5227
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Leishmania major proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Brugia malayi Proteasome A-type and B-type family protein 0.0238 0.313 0.3115
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0037 0.0021 0.0031
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0037 0.0021 0.0031
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0075 0.06 0.058
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0075 0.06 0.0879
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0191 0.2393 0.3506
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0058 0.034 0.034
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0238 0.313 0.4568
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0294 0.3994 0.4329
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0037 0.0021 0.0021
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0191 0.2393 0.3506
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0401 0.5636 1
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.007 0.0519 0.0731
Toxoplasma gondii SAC3/GANP family protein 0.0055 0.0294 0.0297
Trypanosoma brucei proteasome beta 7 subunit 0.0238 0.313 0.4585
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0058 0.034 0.0319
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5387
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0058 0.034 0.0369
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0238 0.313 0.4585
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0252 0.3335 0.3626
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0063 0.0416 0.0609
Plasmodium vivax proteasome subunit beta type-3, putative 0.0242 0.3179 0.4641
Echinococcus granulosus proteasome prosome macropain 0.0478 0.6826 0.6826
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0238 0.313 0.3115
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0238 0.313 0.3387
Schistosoma mansoni hypothetical protein 0.0411 0.5795 0.5786
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.005 0.0217 0.0217
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0041 0.0074 0.0077
Toxoplasma gondii proteasome beta subunit 0.0242 0.3179 0.3441
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0063 0.0416 0.0609
Trypanosoma brucei proteasome alpha 7 subunit 0.0256 0.3398 0.4979
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0294 0.3994 0.5839
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0191 0.2393 0.3506
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0058 0.0335 0.0461
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0275 0.3687 0.3674
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0252 0.3335 0.3335
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0038 0.0056
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.007 0.0519 0.076
Toxoplasma gondii proteasome subunit 0.0254 0.3363 0.3641
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0039 0.0038 0.0056
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0242 0.3179 0.3164
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0055 0.0294 0.0431
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0058 0.034 0.0468
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0063 0.0416 0.0609
Onchocerca volvulus 0.0039 0.0038 0.003
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0041 0.0074 0.0077
Entamoeba histolytica 19S cap proteasome S2 subunit 0.004 0.0056 0.005
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0075 0.06 0.058
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0041 0.0074 0.0074
Entamoeba histolytica proteasome regulatory subunit, putative 0.0058 0.0335 0.0461
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0631 0.9198 1
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0167 0.2031 0.2031
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0231 0.3016 0.4402
Toxoplasma gondii proteasome regulatory subunit 0.0058 0.034 0.0347
Echinococcus multilocularis proteasome subunit beta type 6 0.0254 0.3363 0.3363
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Toxoplasma gondii PCI domain-containing protein 0.007 0.0519 0.0542
Echinococcus granulosus Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0055 0.0294 0.0273
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0478 0.6826 1
Leishmania major proteasome beta 5 subunit, putative 0.0478 0.6826 1
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0055 0.0294 0.0294
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0055 0.0294 0.0273
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.0098 0.0962 0.1383
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Echinococcus granulosus proteasome subunit beta type 7 0.0683 1 1
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0478 0.6826 1
Entamoeba histolytica proteasome regulatory subunit, putative 0.0063 0.0419 0.0585
Giardia lamblia 20S proteasome alpha subunit 5 0.0275 0.3687 0.5402
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0039 0.0038 0.0018
Echinococcus granulosus adhesion regulating molecule 1 0.0631 0.9198 0.9198
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0074 0.0591 0.0866
Brugia malayi Proteasome A-type and B-type family protein 0.0478 0.6826 0.6819
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0254 0.3363 0.4927
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0074 0.0591 0.0866
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0252 0.3335 0.3321
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.007 0.0519 0.0731
Echinococcus granulosus Proteasome subunit alpha beta 0.0256 0.3398 0.3398
Loa Loa (eye worm) hypothetical protein 0.0055 0.0294 0.032
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0276 0.3715 0.5443
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0039 0.0038 0.0025
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0252 0.3335 0.4887
Entamoeba histolytica proteasome regulatory subunit, putative 0.0055 0.0294 0.0401
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0242 0.3179 0.4641
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0037 0.0021 0.0031
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0262 0.3498 0.3803
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0275 0.3687 0.5387
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0038 0.0056
Leishmania major proteasome regulatory ATPase subunit 0.0037 0.0021 0.0031
Loa Loa (eye worm) PAS-3 protein 0.0222 0.2869 0.3119
Echinococcus multilocularis proteasome subunit alpha type 2 0.0262 0.3498 0.3498
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0063 0.0419 0.0419
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0238 0.313 0.313
Leishmania major proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0294 0.3994 0.3994
Leishmania major proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0063 0.0419 0.0434
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0242 0.3179 0.4658
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0262 0.3498 0.3788
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.007 0.0519 0.076
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.007 0.0519 0.0519
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0058 0.034 0.0319
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0238 0.313 0.4585
Echinococcus granulosus proteasome subunit beta type 6 0.0254 0.3363 0.3363
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0478 0.6826 1
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0294 0.3994 0.3981
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0037 0.0021 0.0031
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0063 0.0416 0.0609
Toxoplasma gondii peptidase, T1 family protein 0.0256 0.3398 0.368
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Loa Loa (eye worm) proteasome subunit beta type 2 0.0242 0.3179 0.3456
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0478 0.6826 0.7421
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0276 0.3715 0.3702
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4871
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0256 0.3398 0.3398
Brugia malayi proteasome subunit alpha type 4 0.0222 0.2869 0.2854
Leishmania major proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0063 0.0416 0.0395
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0242 0.3179 0.3441
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0056 0.0309 0.0453
Giardia lamblia 20S proteasome alpha subunit 3 0.0253 0.335 0.4908
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Plasmodium vivax proteasome subunit beta type-4, putative 0.0238 0.313 0.4568
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.005 0.0217 0.0317
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0041 0.0072 0.0106
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.0039 0.0038 0.0056
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0075 0.06 0.06
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0275 0.3687 0.5402
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.004 0.0056 0.0082
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0275 0.3687 0.5402
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0058 0.0335 0.0491
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0253 0.335 0.3336
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0262 0.3498 0.5109
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0039 0.0038 0.0038
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0074 0.0591 0.0866
Entamoeba histolytica proteasome regulatory subunit, putative 0.0075 0.06 0.085
Leishmania major proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0231 0.3016 0.4419
Schistosoma mansoni proteasome regulatory subunit-related 0.0063 0.0419 0.0399
Echinococcus granulosus proteasome subunit beta t family 0.0242 0.3179 0.3179
Entamoeba histolytica proteasome regulatory subunit, putative 0.0063 0.0416 0.058
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0167 0.2031 0.2031
Brugia malayi 26S proteasome subunit P45 family protein 0.0039 0.0038 0.0017
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0018
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0683 1 1
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0058 0.034 0.0347
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0275 0.3687 0.5387
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0591
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0037 0.0021 0.0021
Loa Loa (eye worm) PCI domain-containing protein 0.0058 0.0335 0.0364
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0058 0.034 0.0319
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0041 0.0072 0.0072
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0329 0.4524 0.6617
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.005 0.0217 0.0196
Giardia lamblia Proteasome subunit beta type 2 0.0242 0.3179 0.4658
Brugia malayi PCI domain containing protein 0.0058 0.0335 0.0314
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0256 0.3398 0.3695
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0058 0.034 0.0468
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0058 0.034 0.0369
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0275 0.3687 0.4008
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0242 0.3179 0.3179
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0276 0.3715 0.5429
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0191 0.2393 0.3486
Brugia malayi PCI domain containing protein 0.0063 0.0419 0.0399
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0039 0.0038 0.0038
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0256 0.3398 0.4963
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Plasmodium vivax proteasome subunit beta type-7, putative 0.0231 0.3016 0.4402
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0063 0.0419 0.0419
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0276 0.3715 0.5429
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0055 0.0294 0.0273
Toxoplasma gondii proteasome subunit alpha1, putative 0.0276 0.3715 0.4025
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0041 0.0072 0.0051
Trypanosoma brucei proteasome beta 6 subunit 0.0294 0.3994 0.5852
Loa Loa (eye worm) RPT-2 protein 0.0039 0.0038 0.0042
Brugia malayi Proteasome subunit alpha type 1 0.0221 0.2854 0.2839
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0252 0.3335 0.3611
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0058 0.0335 0.0335
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0231 0.3016 0.4419
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0041 0.0074 0.0108
Loa Loa (eye worm) hypothetical protein 0.0051 0.0229 0.0248
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0276 0.3715 0.4039
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0039 0.0038 0.0025
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4871
Brugia malayi Ubiquitin interaction motif family protein 0.0041 0.0072 0.0051
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.005 0.0217 0.0213
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0242 0.3179 0.3164
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0058 0.034 0.0497
Toxoplasma gondii proteasome subunit alpha type, putative 0.0156 0.1858 0.2001
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0253 0.335 0.4908
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0058 0.0335 0.0491
Leishmania major proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0063 0.0416 0.0416
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0063 0.0416 0.0395
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0063 0.0416 0.058
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0411 0.5795 0.5786
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0058 0.0335 0.0461
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0478 0.6826 1
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0063 0.0419 0.0585
Schistosoma mansoni 26S proteasome subunit S9 0.007 0.0519 0.0498
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0039 0.0038 0.0017
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0039 0.0038 0.0025
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0347 0.4808 0.7035
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0231 0.3016 0.4419
Plasmodium vivax proteasome subunit beta type-1, putative 0.0294 0.3994 0.5839
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0276 0.3715 0.5429
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5387
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Plasmodium falciparum proteasome subunit beta type-5 0.0478 0.6826 1
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0055 0.0294 0.0401
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0037 0.0021 0.0023
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0253 0.335 0.4892
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0044 0.012 0.0131
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.3335 0.4887
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Echinococcus granulosus proteasome subunit alpha type 6 0.0276 0.3715 0.3715
Brugia malayi Proteasome subunit alpha type 7-1 0.0347 0.4808 0.4797
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0063 0.0419 0.0614
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0256 0.3398 0.4963
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Brugia malayi proteasome subunit alpha type 1 0.0252 0.3335 0.3321
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0025
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0055 0.0294 0.0431
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0256 0.3398 0.3384
Brugia malayi proteasome subunit alpha type 2 0.0262 0.3498 0.3484
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0478 0.6826 1
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0254 0.3363 0.3349
Giardia lamblia Hypothetical protein 0.007 0.0519 0.076
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0478 0.6826 1
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0294 0.3994 0.3994
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0041 0.0072 0.0106
Giardia lamblia 26S protease regulatory subunit 7 0.0037 0.0021 0.0031
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0256 0.3398 0.4963
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0254 0.3363 0.4911
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0058 0.034 0.034
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0055 0.0294 0.0431
Schistosoma mansoni multiubiquitin binding protein S5a 0.0041 0.0072 0.0051
Brugia malayi Proteasome/cyclosome repeat family protein 0.0044 0.012 0.0099
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0041 0.0072 0.0106
Giardia lamblia 26S protease regulatory subunit 6A 0.0041 0.0074 0.0108
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0074 0.0591 0.0642
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0044 0.012 0.0176
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0347 0.4808 0.4797
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Brugia malayi Proteasome A-type and B-type family protein 0.0254 0.3363 0.3349
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0478 0.6826 1
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0591
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0063 0.0419 0.0585
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4887
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0041 0.0074 0.0057
Brugia malayi proteasome subunit alpha type 6 0.0276 0.3715 0.3702
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0042
Echinococcus multilocularis proteasome subunit alpha type 6 0.0276 0.3715 0.3715
Loa Loa (eye worm) RPN-3 protein 0.0075 0.06 0.0652
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0074 0.0591 0.0866
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0222 0.2875 0.4211
Loa Loa (eye worm) hypothetical protein 0.0055 0.0294 0.032
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0253 0.335 0.335
Loa Loa (eye worm) hypothetical protein 0.0411 0.5795 0.63
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Loa Loa (eye worm) proteasome subunit beta type 1 0.0294 0.3994 0.4342
Trichomonas vaginalis 26S proteasome subunit, putative 0.0058 0.0335 0.0491
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0275 0.3687 0.3674
Toxoplasma gondii hypothetical protein 0.0051 0.0229 0.0226
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0242 0.3179 0.3179
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0262 0.3498 0.5109
Plasmodium vivax proteasome subunit beta type-5, putative 0.0478 0.6826 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0254 0.3363 0.3656
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0231 0.3016 0.3264
Onchocerca volvulus Notchless protein homolog 0.0256 0.3398 0.6014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0021 0.0023
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Brugia malayi proteasome subunit beta type 3 0.0242 0.3179 0.3164
Mycobacterium ulcerans proteasome PrcB 0.0478 0.6826 1
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0253 0.335 0.335
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0058 0.034 0.0497
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0075 0.06 0.06
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0256 0.3398 0.4979
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0242 0.3179 0.3179
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Plasmodium falciparum proteasome subunit beta type-4 0.0238 0.313 0.4568
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0063 0.0419 0.0614
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0231 0.3016 0.4419
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0254 0.3363 0.4927
Brugia malayi 20S proteasome alpha5 subunit 0.0275 0.3687 0.3674
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0058 0.034 0.034
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0478 0.6826 0.6819
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0058 0.034 0.0319
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0191 0.2393 0.3486
Plasmodium vivax proteasome subunit beta type-2, putative 0.0242 0.3179 0.4641
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0478 0.6826 1
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0253 0.335 0.4892
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0041 0.0074 0.008
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.313 0.4585
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0074 0.0591 0.0866
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0262 0.3498 0.3484
Giardia lamblia 20S proteasome alpha subunit 4 0.0347 0.4808 0.7045
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Entamoeba histolytica hypothetical protein 0.005 0.0217 0.0287
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0347 0.4808 0.7045
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0039 0.0038 0.0025
Entamoeba histolytica proteasome regulatory subunit, putative 0.007 0.0519 0.0731
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0231 0.3016 0.3279
Echinococcus multilocularis proteasome (prosome, macropain) 0.0478 0.6826 0.6826
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.007 0.0519 0.0498
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0275 0.3687 0.3687
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0191 0.2393 0.3506
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0025
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0242 0.3179 0.3164
Echinococcus multilocularis adhesion regulating molecule 1 0.0631 0.9198 0.9198
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0041 0.0073 0.0107
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0039 0.0038 0.0038
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0058 0.0335 0.0491
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Brugia malayi Probable 26S protease regulatory subunit 4 0.0039 0.0038 0.0017
Echinococcus granulosus subfamily T1A non peptidase ue 0.0275 0.3687 0.3687
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0256 0.3398 0.4963
Echinococcus granulosus 26S protease regulatory subunit 8 0.0037 0.0021 0.0021
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0253 0.335 0.4892
Toxoplasma gondii proteasome subunit beta type, putative 0.0478 0.6826 0.7414
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0075 0.06 0.058
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0058 0.034 0.034
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0055 0.0294 0.0401
Loa Loa (eye worm) proteasome Regulatory Particle 0.0063 0.0416 0.0452
Echinococcus multilocularis proteasome subunit beta type 7 0.0683 1 1
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0063 0.0416 0.0609
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.005 0.0217 0.0287
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0231 0.3016 0.4402
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0191 0.2393 0.3486
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0041 0.0074 0.0074
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0058 0.034 0.0468
Toxoplasma gondii PCI domain-containing protein 0.0075 0.06 0.0631
Toxoplasma gondii heat shock protein hslv, putative 0.0191 0.2393 0.2585
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0074 0.0591 0.0571
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0294 0.3994 0.5852
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.007 0.0519 0.0519
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0058 0.0335 0.0491
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0041
Loa Loa (eye worm) PCI domain-containing protein 0.0063 0.0419 0.0456
Leishmania major proteasome beta 7 subunit, putative 0.0238 0.313 0.4585
Loa Loa (eye worm) proteasome regulatory particle 0.007 0.0519 0.0564
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0058 0.034 0.0468
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0252 0.3335 0.4871
Entamoeba histolytica proteasome regulatory subunit, putative 0.0041 0.0072 0.0074
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0074 0.0591 0.0837
Onchocerca volvulus 0.0039 0.0038 0.003
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Toxoplasma gondii proteasome 26S regulatory subunit 0.004 0.0056 0.0037
Giardia lamblia 20S proteasome alpha subunit 6 0.0252 0.3335 0.4887
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0058 0.034 0.0497
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0058 0.0335 0.0335
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0037 0.0021 0.0031
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0037 0.0021 0.0031
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0252 0.3335 0.3335
Plasmodium vivax proteasome subunit beta type-6, putative 0.0254 0.3363 0.4911
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0041 0.0074 0.0108
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Giardia lamblia 26S protease regulatory subunit 8 0.0037 0.0021 0.0031
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0039 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0631 0.9198 1
Leishmania major hypothetical protein, conserved 0.0329 0.4524 0.6628
Giardia lamblia 26S protease regulatory subunit 6B 0.0039 0.0038 0.0056
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0254 0.3363 0.4911
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0075 0.06 0.085
Echinococcus granulosus proteasome subunit alpha type 2 0.0262 0.3498 0.3498
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0347 0.4808 0.7035
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0242 0.3179 0.4641
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0058 0.034 0.0468
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.313 0.3402
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0242 0.3179 0.4641
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0063 0.0419 0.0614
Giardia lamblia 20S proteasome alpha subunit 1 0.0276 0.3715 0.5443
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0631 0.9198 0.9197
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0058 0.034 0.0468
Brugia malayi proteasome subunit alpha type 3 0.0256 0.3398 0.3384
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.0039 0.0038 0.0056
Giardia lamblia 20S proteasome alpha subunit 7 0.0256 0.3398 0.4979
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.007 0.0519 0.076
Schistosoma mansoni hypothetical protein 0.0058 0.0335 0.0314
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Leishmania major proteasome alpha 1 subunit, putative 0.0252 0.3335 0.4887
Brugia malayi proteasome subunit beta type 2 0.0242 0.3179 0.3164
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.005 0.0217 0.0217
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0253 0.335 0.4892
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0275 0.3687 0.3994
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0074 0.0591 0.0837
Schistosoma mansoni 26S protease regulatory subunit 0.0039 0.0038 0.0017
Schistosoma mansoni hypothetical protein 0.0167 0.2031 0.2013
Brugia malayi Proteasome/cyclosome repeat family protein 0.0044 0.012 0.0099
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0063 0.0419 0.0614
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0055 0.0294 0.0294
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0242 0.3179 0.3164
Giardia lamblia Proteasome subunit beta type 1 0.0294 0.3994 0.5852
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0191 0.2393 0.2377
Toxoplasma gondii proteasome subunit alpha type, putative 0.0253 0.335 0.3627
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Toxoplasma gondii PCI domain-containing protein 0.0058 0.0335 0.0342
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0347 0.4808 0.7035
Loa Loa (eye worm) proteasome 26S subunit 0.0037 0.0021 0.0023
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.005 0.0217 0.0287
Leishmania major proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Leishmania major proteasome beta 2 subunit, putative 0.0242 0.3179 0.4658

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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