Detailed information for compound 1551297

Basic information

Technical information
  • TDR Targets ID: 1551297
  • Name: N-[(2S)-1-(4,5-dihydro-1,3-thiazol-2-ylamino) -3-methyl-1-oxobutan-2-yl]-3,5-dimethoxybenza mide
  • MW: 365.447 | Formula: C17H23N3O4S
  • H donors: 2 H acceptors: 2 LogP: 2.26 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)cc(c1)C(=O)N[C@H](C(=O)NC1=NCCS1)C(C)C
  • InChi: 1S/C17H23N3O4S/c1-10(2)14(16(22)20-17-18-5-6-25-17)19-15(21)11-7-12(23-3)9-13(8-11)24-4/h7-10,14H,5-6H2,1-4H3,(H,19,21)(H,18,20,22)/t14-/m0/s1
  • InChiKey: ZOWLWIJXWKUDAJ-AWEZNQCLSA-N  

Network

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Synonyms

  • N-[(1S)-1-(4,5-dihydrothiazol-2-ylcarbamoyl)-2-methyl-propyl]-3,5-dimethoxy-benzamide
  • N-[(1S)-1-[(4,5-dihydrothiazol-2-ylamino)-oxomethyl]-2-methylpropyl]-3,5-dimethoxybenzamide
  • N-[(2S)-1-(4,5-dihydro-1,3-thiazol-2-ylamino)-3-methyl-1-oxo-butan-2-yl]-3,5-dimethoxy-benzamide
  • T5252869
  • ZINC02661064

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0041 0.0072 0.0106
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0242 0.3179 0.4641
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0256 0.3398 0.3384
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0055 0.0294 0.0273
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0478 0.6826 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.313 0.3402
Schistosoma mansoni hypothetical protein 0.0167 0.2031 0.2013
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0039 0.0038 0.0056
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0025
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0058 0.0335 0.0335
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0275 0.3687 0.4008
Loa Loa (eye worm) RPT-2 protein 0.0039 0.0038 0.0042
Schistosoma mansoni 26S protease regulatory subunit 0.0039 0.0038 0.0017
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0058 0.034 0.0468
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Echinococcus multilocularis proteasome subunit beta type 7 0.0683 1 1
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0039 0.0038 0.0038
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0037 0.0021 0.0021
Echinococcus granulosus proteasome subunit beta type 7 0.0683 1 1
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0041 0.0074 0.0077
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.0039 0.0038 0.0056
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0074 0.0591 0.0837
Loa Loa (eye worm) proteasome Regulatory Particle 0.0063 0.0416 0.0452
Entamoeba histolytica 19S cap proteasome S2 subunit 0.004 0.0056 0.005
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0347 0.4808 0.7045
Brugia malayi Ubiquitin interaction motif family protein 0.0041 0.0072 0.0051
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0262 0.3498 0.5109
Giardia lamblia 26S protease regulatory subunit 8 0.0037 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0042
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0063 0.0416 0.0609
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.0039 0.0038 0.0056
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0039 0.0038 0.0025
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0063 0.0416 0.0609
Plasmodium falciparum proteasome subunit beta type-4 0.0238 0.313 0.4568
Loa Loa (eye worm) RPN-3 protein 0.0075 0.06 0.0652
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0039 0.0038 0.0038
Giardia lamblia 20S proteasome alpha subunit 4 0.0347 0.4808 0.7045
Echinococcus granulosus proteasome subunit beta t family 0.0242 0.3179 0.3179
Brugia malayi 26S proteasome subunit P45 family protein 0.0039 0.0038 0.0017
Leishmania major proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Brugia malayi proteasome subunit beta type 1 0.0294 0.3994 0.3981
Trypanosoma brucei proteasome beta 6 subunit 0.0294 0.3994 0.5852
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0275 0.3687 0.5387
Schistosoma mansoni proteasome regulatory subunit-related 0.0063 0.0419 0.0399
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0063 0.0419 0.0614
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0058 0.0335 0.0491
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5387
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0253 0.335 0.4892
Leishmania major proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Plasmodium vivax proteasome subunit beta type-1, putative 0.0294 0.3994 0.5839
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.007 0.0519 0.076
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0041 0.0074 0.0074
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0262 0.3498 0.5109
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Toxoplasma gondii peptidase, T1 family protein 0.0256 0.3398 0.368
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.005 0.0217 0.0287
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0063 0.0416 0.058
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0037 0.0021 0.0031
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.005 0.0217 0.0287
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0044 0.012 0.0131
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0591
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0252 0.3335 0.4887
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0631 0.9198 0.9197
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0058 0.0335 0.0491
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0256 0.3398 0.4963
Echinococcus granulosus Proteasome subunit alpha beta 0.0256 0.3398 0.3398
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0038 0.0056
Giardia lamblia 20S proteasome alpha subunit 6 0.0252 0.3335 0.4887
Toxoplasma gondii proteasome subunit alpha1, putative 0.0276 0.3715 0.4025
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0252 0.3335 0.3321
Brugia malayi proteasome subunit alpha type 2 0.0262 0.3498 0.3484
Brugia malayi PCI domain containing protein 0.0058 0.0335 0.0314
Schistosoma mansoni multiubiquitin binding protein S5a 0.0041 0.0072 0.0051
Toxoplasma gondii PCI domain-containing protein 0.007 0.0519 0.0542
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0478 0.6826 0.6819
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5387
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0478 0.6826 1
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0294 0.3994 0.5839
Loa Loa (eye worm) hypothetical protein 0.0631 0.9198 1
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0063 0.0416 0.0609
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0037 0.0021 0.0031
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0191 0.2393 0.3486
Leishmania major proteasome beta 7 subunit, putative 0.0238 0.313 0.4585
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.313 0.4585
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0294 0.3994 0.5839
Onchocerca volvulus Notchless protein homolog 0.0256 0.3398 0.6014
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0039 0.0038 0.0025
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0075 0.06 0.058
Toxoplasma gondii proteasome subunit 0.0254 0.3363 0.3641
Brugia malayi proteasome subunit alpha type 3 0.0256 0.3398 0.3384
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0191 0.2393 0.3486
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.007 0.0519 0.076
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0347 0.4808 0.7035
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0075 0.06 0.06
Giardia lamblia 20S proteasome alpha subunit 2 0.0262 0.3498 0.5124
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0231 0.3016 0.4402
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0075 0.06 0.085
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Echinococcus granulosus proteasome subunit alpha type 6 0.0276 0.3715 0.3715
Toxoplasma gondii proteasome subunit beta type, putative 0.0478 0.6826 0.7414
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0058 0.0335 0.0461
Brugia malayi proteasome subunit beta type 2 0.0242 0.3179 0.3164
Entamoeba histolytica proteasome regulatory subunit, putative 0.0063 0.0416 0.058
Giardia lamblia Proteasome subunit beta type 2 0.0242 0.3179 0.4658
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0238 0.313 0.313
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0039 0.0038 0.0025
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.0039 0.0038 0.0056
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0294 0.3994 0.5852
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0253 0.335 0.4892
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0063 0.0419 0.0614
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0058 0.0335 0.0461
Entamoeba histolytica proteasome regulatory subunit, putative 0.007 0.0519 0.0731
Toxoplasma gondii proteasome beta subunit 0.0242 0.3179 0.3441
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0039 0.0038 0.0038
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.007 0.0519 0.076
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0018
Toxoplasma gondii SAC3/GANP family protein 0.0055 0.0294 0.0297
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0058 0.034 0.0369
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0254 0.3363 0.3349
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0058 0.034 0.0319
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0041 0.0074 0.008
Brugia malayi Proteasome subunit alpha type 7-1 0.0347 0.4808 0.4797
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0074 0.0591 0.0866
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0058 0.034 0.0468
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0063 0.0419 0.0434
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0191 0.2393 0.2377
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0276 0.3715 0.3702
Leishmania major hypothetical protein, conserved 0.0329 0.4524 0.6628
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0238 0.313 0.3115
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0063 0.0419 0.0585
Leishmania major proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0039 0.0038 0.0018
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0058 0.034 0.0497
Giardia lamblia Hypothetical protein 0.007 0.0519 0.076
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0063 0.0416 0.0416
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0242 0.3179 0.3164
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0256 0.3398 0.3695
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Giardia lamblia 26S protease regulatory subunit 6A 0.0041 0.0074 0.0108
Schistosoma mansoni 26S proteasome subunit S9 0.007 0.0519 0.0498
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0058 0.034 0.0468
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0242 0.3179 0.3164
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0063 0.0419 0.0614
Brugia malayi Proteasome A-type and B-type family protein 0.0478 0.6826 0.6819
Toxoplasma gondii proteasome regulatory subunit 0.0058 0.034 0.0347
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0478 0.6826 0.7421
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0063 0.0416 0.058
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0167 0.2031 0.2031
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0256 0.3398 0.4979
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0242 0.3179 0.4641
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0075 0.06 0.058
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0041 0.0072 0.0051
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0063 0.0416 0.0395
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0256 0.3398 0.4963
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0063 0.0416 0.043
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0256 0.3398 0.4963
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0275 0.3687 0.5387
Mycobacterium ulcerans proteasome PrcB 0.0478 0.6826 1
Giardia lamblia Proteasome subunit beta type 3 0.0242 0.3179 0.4658
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0191 0.2393 0.3506
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0478 0.6826 1
Onchocerca volvulus 0.0039 0.0038 0.003
Brugia malayi Probable 26S protease regulatory subunit 4 0.0039 0.0038 0.0017
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0058 0.034 0.0468
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.0039 0.0038 0.0056
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4871
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0041 0.0074 0.0057
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.0098 0.0962 0.1383
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0242 0.3179 0.3179
Leishmania major proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0231 0.3016 0.4419
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0037 0.0021 0.0023
Plasmodium vivax proteasome subunit beta type-2, putative 0.0242 0.3179 0.4641
Trichomonas vaginalis 26S proteasome subunit, putative 0.0058 0.0335 0.0491
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0041 0.0074 0.0108
Loa Loa (eye worm) hypothetical protein 0.0037 0.0021 0.0023
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Leishmania major proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0238 0.313 0.4585
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0058 0.034 0.0369
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0253 0.335 0.4892
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Leishmania major proteasome alpha 1 subunit, putative 0.0252 0.3335 0.4887
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0063 0.0419 0.0614
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0276 0.3715 0.5429
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0058 0.034 0.0468
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0055 0.0294 0.0273
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0231 0.3016 0.4419
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0075 0.06 0.0879
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.007 0.0519 0.0519
Plasmodium falciparum proteasome subunit beta type-5 0.0478 0.6826 1
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0039 0.0038 0.0025
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0074 0.0591 0.0571
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Brugia malayi Proteasome/cyclosome repeat family protein 0.0044 0.012 0.0099
Brugia malayi 20S proteasome alpha5 subunit 0.0275 0.3687 0.3674
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0075 0.06 0.06
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0294 0.3994 0.3994
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0074 0.0591 0.0866
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0075 0.06 0.058
Loa Loa (eye worm) hypothetical protein 0.0055 0.0294 0.032
Brugia malayi Proteasome A-type and B-type family protein 0.0238 0.313 0.3115
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.005 0.0217 0.0217
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0063 0.0419 0.0419
Brugia malayi PCI domain containing protein 0.0063 0.0419 0.0399
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0074 0.0591 0.0837
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0058 0.034 0.0468
Echinococcus multilocularis proteasome subunit beta type 6 0.0254 0.3363 0.3363
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0037 0.0021 0.0021
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0041 0.0072 0.0072
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0347 0.4808 0.7035
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Loa Loa (eye worm) PCI domain-containing protein 0.0063 0.0419 0.0456
Plasmodium vivax proteasome subunit beta type-4, putative 0.0238 0.313 0.4568
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.004 0.0056 0.0082
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Brugia malayi Proteasome subunit alpha type 1 0.0221 0.2854 0.2839
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0242 0.3179 0.3164
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0329 0.4524 0.6617
Toxoplasma gondii proteasome subunit alpha type, putative 0.0253 0.335 0.3627
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0253 0.335 0.4908
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0063 0.0416 0.0395
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0262 0.3498 0.3788
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0591
Giardia lamblia 26S protease regulatory subunit 7 0.0037 0.0021 0.0031
Echinococcus multilocularis adhesion regulating molecule 1 0.0631 0.9198 0.9198
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.005 0.0217 0.0317
Echinococcus multilocularis proteasome (prosome, macropain) 0.0478 0.6826 0.6826
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0411 0.5795 0.5786
Echinococcus multilocularis proteasome subunit alpha type 2 0.0262 0.3498 0.3498
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0058 0.034 0.034
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0025
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0242 0.3179 0.3179
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0055 0.0294 0.0401
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0243 0.3206 0.3191
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0262 0.3498 0.5109
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0231 0.3016 0.4419
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0058 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0055 0.0294 0.032
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0253 0.335 0.335
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.007 0.0519 0.0731
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0058 0.0335 0.0491
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0056 0.0309 0.0453
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0038 0.0056
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Giardia lamblia 20S proteasome alpha subunit 1 0.0276 0.3715 0.5443
Leishmania major proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0254 0.3363 0.4927
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0058 0.0335 0.0491
Echinococcus granulosus proteasome subunit beta type 6 0.0254 0.3363 0.3363
Echinococcus multilocularis proteasome subunit alpha type 6 0.0276 0.3715 0.3715
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0254 0.3363 0.4927
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0063 0.0416 0.0609
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0347 0.4808 0.7035
Schistosoma mansoni hypothetical protein 0.0058 0.0335 0.0314
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0275 0.3687 0.3994
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.007 0.0519 0.0498
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0058 0.034 0.0347
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4887
Entamoeba histolytica proteasome regulatory subunit, putative 0.0075 0.06 0.085
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0256 0.3398 0.4963
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0075 0.06 0.0879
Trypanosoma cruzi 20S proteasome subunit 0.0242 0.3179 0.4658
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0037 0.0021 0.0031
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0254 0.3363 0.4911
Entamoeba histolytica hypothetical protein 0.005 0.0217 0.0287
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0055 0.0294 0.0294
Loa Loa (eye worm) proteasome subunit beta type 2 0.0242 0.3179 0.3456
Toxoplasma gondii proteasome subunit alpha type, putative 0.0156 0.1858 0.2001
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0041 0.0074 0.0074
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.3335 0.4887
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0074 0.0591 0.0866
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0063 0.0419 0.0419
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0041 0.0072 0.0072
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0275 0.3687 0.5402
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0039 0.0038 0.0038
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0276 0.3715 0.4039
Trypanosoma brucei proteasome beta 7 subunit 0.0238 0.313 0.4585
Echinococcus granulosus adhesion regulating molecule 1 0.0631 0.9198 0.9198
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0631 0.9198 1
Loa Loa (eye worm) proteasome subunit beta type 3 0.0242 0.3179 0.3456
Loa Loa (eye worm) PCI domain-containing protein 0.0058 0.0335 0.0364
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0058 0.034 0.0497
Toxoplasma gondii PCI domain-containing protein 0.0075 0.06 0.0631
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0262 0.3498 0.3803
Toxoplasma gondii proteasome 26S regulatory subunit 0.004 0.0056 0.0037
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0478 0.6826 1
Loa Loa (eye worm) proteasome subunit beta type 1 0.0294 0.3994 0.4342
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0058 0.034 0.0497
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0347 0.4808 0.4797
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0253 0.335 0.4892
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0058 0.034 0.034
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0041 0.0072 0.0106
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0252 0.3335 0.3335
Onchocerca volvulus 0.0039 0.0038 0.003
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0275 0.3687 0.5402
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0037 0.0021 0.0021
Giardia lamblia Proteasome subunit beta type 1 0.0294 0.3994 0.5852
Loa Loa (eye worm) hypothetical protein 0.0411 0.5795 0.63
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0039 0.0038 0.0017
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0167 0.2031 0.2031
Brugia malayi Proteasome/cyclosome repeat family protein 0.0044 0.012 0.0099
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Loa Loa (eye worm) proteasome regulatory particle 0.007 0.0519 0.0564
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0253 0.335 0.335
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0058 0.034 0.0319
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0191 0.2393 0.5
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0055 0.0294 0.0273
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0401 0.5636 1
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0037 0.0021 0.0031
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0231 0.3016 0.3279
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0238 0.313 0.313
Entamoeba histolytica proteasome regulatory subunit, putative 0.0055 0.0294 0.0401
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0294 0.3994 0.4329
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0041 0.0074 0.0108
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0231 0.3016 0.4402
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0276 0.3715 0.5443
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0275 0.3687 0.3687
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0041
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0242 0.3179 0.3164
Leishmania major proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.005 0.0217 0.0213
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0074 0.0591 0.0866
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Echinococcus granulosus Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0044 0.012 0.0176
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Giardia lamblia 20S proteasome alpha subunit 3 0.0253 0.335 0.4908
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.007 0.0519 0.0731
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0055 0.0294 0.0431
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0231 0.3016 0.4419
Plasmodium vivax proteasome subunit beta type-3, putative 0.0242 0.3179 0.4641
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0191 0.2393 0.3486
Toxoplasma gondii hypothetical protein 0.0051 0.0229 0.0226
Brugia malayi proteasome subunit alpha type 6 0.0276 0.3715 0.3702
Schistosoma mansoni hypothetical protein 0.0411 0.5795 0.5786
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0478 0.6826 1
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.007 0.0519 0.076
Leishmania major proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0238 0.313 0.4568
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0262 0.3498 0.3484
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0253 0.335 0.3336
Loa Loa (eye worm) hypothetical protein 0.0051 0.0229 0.0248
Brugia malayi 26S protease regulatory subunit 6A 0.0041 0.0074 0.0053
Brugia malayi proteasome subunit beta type 3 0.0242 0.3179 0.3164
Brugia malayi Proteasome A-type and B-type family protein 0.0254 0.3363 0.3349
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0242 0.3179 0.3441
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0478 0.6826 1
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0191 0.2393 0.3506
Entamoeba histolytica proteasome regulatory subunit, putative 0.0058 0.0335 0.0461
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0055 0.0294 0.0401
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0075 0.06 0.0879
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0683 1 1
Toxoplasma gondii PCI domain-containing protein 0.0058 0.0335 0.0342
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0041 0.0072 0.0106
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0055 0.0294 0.0294
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0347 0.4808 0.5227
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.005 0.0217 0.0196
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.007 0.0519 0.0519
Leishmania major proteasome beta 2 subunit, putative 0.0242 0.3179 0.4658
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0074 0.0591 0.0866
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0055 0.0294 0.0431
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Giardia lamblia 26S protease regulatory subunit 6B 0.0039 0.0038 0.0056
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0039 0.0038 0.0056
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0347 0.4808 0.7035
Plasmodium vivax proteasome subunit beta type-6, putative 0.0254 0.3363 0.4911
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0037 0.0021 0.0031
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0063 0.0419 0.0585
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0242 0.3179 0.3179
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0256 0.3398 0.3398
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0055 0.0294 0.0431
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0275 0.3687 0.3674
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Loa Loa (eye worm) proteasome 26S subunit 0.0037 0.0021 0.0023
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0238 0.313 0.4585
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0063 0.0416 0.0609
Trypanosoma brucei proteasome alpha 7 subunit 0.0256 0.3398 0.4979
Entamoeba histolytica proteasome regulatory subunit, putative 0.0041 0.0072 0.0074
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0222 0.2875 0.4211
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0063 0.0416 0.0416
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0191 0.2393 0.3506
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0231 0.3016 0.3264
Plasmodium vivax proteasome subunit beta type-7, putative 0.0231 0.3016 0.4402
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0041 0.0074 0.0077
Leishmania major proteasome beta 5 subunit, putative 0.0478 0.6826 1
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0254 0.3363 0.4911
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0041 0.0074 0.0077
Echinococcus granulosus proteasome subunit alpha type 2 0.0262 0.3498 0.3498
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0294 0.3994 0.3981
Toxoplasma gondii heat shock protein hslv, putative 0.0191 0.2393 0.2585
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Entamoeba histolytica proteasome regulatory subunit, putative 0.0063 0.0419 0.0585
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4871
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0275 0.3687 0.3674
Echinococcus granulosus subfamily T1A non peptidase ue 0.0275 0.3687 0.3687
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0058 0.034 0.034
Giardia lamblia 20S proteasome alpha subunit 5 0.0275 0.3687 0.5402
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0191 0.2393 0.3506
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0242 0.3179 0.4641
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0238 0.313 0.3387
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0478 0.6826 1
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0252 0.3335 0.4871
Brugia malayi proteasome subunit alpha type 1 0.0252 0.3335 0.3321
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0478 0.6826 1
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0037 0.0021 0.0031
Leishmania major proteasome regulatory ATPase subunit 0.0037 0.0021 0.0031
Echinococcus granulosus proteasome prosome macropain 0.0478 0.6826 0.6826
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0252 0.3335 0.3626
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0242 0.3179 0.4658
Loa Loa (eye worm) PAS-3 protein 0.0222 0.2869 0.3119
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0294 0.3994 0.3994
Echinococcus granulosus 26S protease regulatory subunit 8 0.0037 0.0021 0.0021
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0252 0.3335 0.3611
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0242 0.3179 0.4641
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0058 0.034 0.0319
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0242 0.3179 0.4658
Brugia malayi proteasome subunit alpha type 4 0.0222 0.2869 0.2854
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0039 0.0038 0.0056
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Giardia lamblia 20S proteasome alpha subunit 7 0.0256 0.3398 0.4979
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0037 0.0021 0.0031
Plasmodium vivax proteasome subunit beta type-5, putative 0.0478 0.6826 1
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0252 0.3335 0.3335
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0631 0.9198 0.9197
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0058 0.034 0.0319
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0276 0.3715 0.5429
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0276 0.3715 0.5429
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0058 0.034 0.034
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0074 0.0591 0.0642
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.005 0.0217 0.0217
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0254 0.3363 0.3656
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0041 0.0073 0.0107
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0037 0.0021 0.0031

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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