Detailed information for compound 1551297

Basic information

Technical information
  • TDR Targets ID: 1551297
  • Name: N-[(2S)-1-(4,5-dihydro-1,3-thiazol-2-ylamino) -3-methyl-1-oxobutan-2-yl]-3,5-dimethoxybenza mide
  • MW: 365.447 | Formula: C17H23N3O4S
  • H donors: 2 H acceptors: 2 LogP: 2.26 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)cc(c1)C(=O)N[C@H](C(=O)NC1=NCCS1)C(C)C
  • InChi: 1S/C17H23N3O4S/c1-10(2)14(16(22)20-17-18-5-6-25-17)19-15(21)11-7-12(23-3)9-13(8-11)24-4/h7-10,14H,5-6H2,1-4H3,(H,19,21)(H,18,20,22)/t14-/m0/s1
  • InChiKey: ZOWLWIJXWKUDAJ-AWEZNQCLSA-N  

Network

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Synonyms

  • N-[(1S)-1-(4,5-dihydrothiazol-2-ylcarbamoyl)-2-methyl-propyl]-3,5-dimethoxy-benzamide
  • N-[(1S)-1-[(4,5-dihydrothiazol-2-ylamino)-oxomethyl]-2-methylpropyl]-3,5-dimethoxybenzamide
  • N-[(2S)-1-(4,5-dihydro-1,3-thiazol-2-ylamino)-3-methyl-1-oxo-butan-2-yl]-3,5-dimethoxy-benzamide
  • T5252869
  • ZINC02661064

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Leishmania major proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Leishmania major proteasome regulatory ATPase subunit 0.0037 0.0021 0.0031
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0039 0.0038 0.0018
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0037 0.0021 0.0021
Trichomonas vaginalis 26S proteasome subunit, putative 0.0058 0.0335 0.0491
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0055 0.0294 0.0431
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0294 0.3994 0.4329
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0074 0.0591 0.0866
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Schistosoma mansoni hypothetical protein 0.0167 0.2031 0.2013
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0231 0.3016 0.4419
Entamoeba histolytica 19S cap proteasome S2 subunit 0.004 0.0056 0.005
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0238 0.313 0.3387
Giardia lamblia 26S protease regulatory subunit 8 0.0037 0.0021 0.0031
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0055 0.0294 0.0273
Leishmania major proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.005 0.0217 0.0217
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.313 0.4585
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4887
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0252 0.3335 0.3321
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0063 0.0416 0.0609
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0058 0.0335 0.0491
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0242 0.3179 0.3164
Brugia malayi Proteasome A-type and B-type family protein 0.0238 0.313 0.3115
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0253 0.335 0.3336
Plasmodium vivax proteasome subunit beta type-6, putative 0.0254 0.3363 0.4911
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0058 0.034 0.0369
Giardia lamblia 20S proteasome alpha subunit 7 0.0256 0.3398 0.4979
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0242 0.3179 0.3164
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0075 0.06 0.0879
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0044 0.012 0.0176
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5387
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0253 0.335 0.4892
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0478 0.6826 1
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0294 0.3994 0.5839
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0074 0.0591 0.0642
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0478 0.6826 1
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0411 0.5795 0.5786
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0063 0.0419 0.0585
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0075 0.06 0.085
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0242 0.3179 0.3179
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.3335 0.4887
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0041 0.0072 0.0072
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0252 0.3335 0.3611
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.007 0.0519 0.0519
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0063 0.0419 0.0614
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0039 0.0038 0.0038
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0058 0.034 0.0497
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0058 0.034 0.0468
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0039 0.0038 0.0056
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0063 0.0419 0.0585
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0631 0.9198 1
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0075 0.06 0.0879
Toxoplasma gondii PCI domain-containing protein 0.007 0.0519 0.0542
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0063 0.0416 0.058
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0275 0.3687 0.3687
Giardia lamblia 20S proteasome alpha subunit 6 0.0252 0.3335 0.4887
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0041 0.0074 0.0077
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0039 0.0038 0.0056
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.004 0.0056 0.0082
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0039 0.0038 0.0025
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0276 0.3715 0.5429
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0254 0.3363 0.4911
Plasmodium vivax proteasome subunit beta type-4, putative 0.0238 0.313 0.4568
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0058 0.034 0.0468
Giardia lamblia Proteasome subunit beta type 1 0.0294 0.3994 0.5852
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0242 0.3179 0.3164
Mycobacterium ulcerans proteasome PrcB 0.0478 0.6826 1
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0039 0.0038 0.0056
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0242 0.3179 0.3441
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0631 0.9198 0.9197
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0055 0.0294 0.0401
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0167 0.2031 0.2031
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0063 0.0416 0.058
Brugia malayi 26S protease regulatory subunit 6A 0.0041 0.0074 0.0053
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0276 0.3715 0.5429
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0167 0.2031 0.2031
Toxoplasma gondii hypothetical protein 0.0051 0.0229 0.0226
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0058 0.034 0.0497
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0191 0.2393 0.3506
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0347 0.4808 0.7035
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0294 0.3994 0.3994
Brugia malayi proteasome subunit beta type 3 0.0242 0.3179 0.3164
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0074 0.0591 0.0866
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.005 0.0217 0.0217
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0037 0.0021 0.0031
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0254 0.3363 0.4927
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0275 0.3687 0.5402
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0683 1 1
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.005 0.0217 0.0287
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0252 0.3335 0.4871
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0242 0.3179 0.3164
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0063 0.0419 0.0614
Brugia malayi proteasome subunit beta type 2 0.0242 0.3179 0.3164
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0037 0.0021 0.0031
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0347 0.4808 0.5227
Brugia malayi 26S proteasome subunit P45 family protein 0.0039 0.0038 0.0017
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0058 0.034 0.0319
Toxoplasma gondii proteasome subunit alpha type, putative 0.0253 0.335 0.3627
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0075 0.06 0.0879
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0041 0.0072 0.0106
Toxoplasma gondii proteasome subunit alpha type, putative 0.0156 0.1858 0.2001
Brugia malayi proteasome subunit alpha type 1 0.0252 0.3335 0.3321
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0075 0.06 0.058
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0055 0.0294 0.0431
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0347 0.4808 0.7035
Leishmania major proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Brugia malayi proteasome subunit beta type 1 0.0294 0.3994 0.3981
Toxoplasma gondii proteasome 26S regulatory subunit 0.004 0.0056 0.0037
Entamoeba histolytica proteasome regulatory subunit, putative 0.0063 0.0416 0.058
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0262 0.3498 0.5109
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0256 0.3398 0.3384
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.0039 0.0038 0.0056
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0631 0.9198 0.9197
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0478 0.6826 1
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0063 0.0416 0.043
Leishmania major proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Loa Loa (eye worm) PCI domain-containing protein 0.0058 0.0335 0.0364
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0275 0.3687 0.3674
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0256 0.3398 0.4963
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4871
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.005 0.0217 0.0196
Brugia malayi Proteasome A-type and B-type family protein 0.0478 0.6826 0.6819
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Loa Loa (eye worm) PAS-3 protein 0.0222 0.2869 0.3119
Brugia malayi proteasome subunit alpha type 3 0.0256 0.3398 0.3384
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0252 0.3335 0.4871
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Loa Loa (eye worm) hypothetical protein 0.0055 0.0294 0.032
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0039 0.0038 0.0025
Loa Loa (eye worm) RPT-2 protein 0.0039 0.0038 0.0042
Plasmodium falciparum proteasome subunit beta type-5 0.0478 0.6826 1
Plasmodium vivax proteasome subunit beta type-1, putative 0.0294 0.3994 0.5839
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0253 0.335 0.4892
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0041 0.0072 0.0051
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0058 0.034 0.0468
Toxoplasma gondii proteasome regulatory subunit 0.0058 0.034 0.0347
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0063 0.0416 0.0609
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0058 0.0335 0.0461
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Plasmodium vivax proteasome subunit beta type-5, putative 0.0478 0.6826 1
Giardia lamblia 20S proteasome alpha subunit 1 0.0276 0.3715 0.5443
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0256 0.3398 0.4979
Echinococcus granulosus Proteasome subunit alpha beta 0.0256 0.3398 0.3398
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0058 0.0335 0.0461
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Brugia malayi 20S proteasome alpha5 subunit 0.0275 0.3687 0.3674
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0191 0.2393 0.3486
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0275 0.3687 0.5387
Leishmania major proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0256 0.3398 0.4963
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0041 0.0074 0.0053
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0039 0.0038 0.0038
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0238 0.313 0.4568
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0478 0.6826 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0478 0.6826 0.7421
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Toxoplasma gondii peptidase, T1 family protein 0.0256 0.3398 0.368
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0037 0.0021 0.0021
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0058 0.034 0.0497
Onchocerca volvulus Notchless protein homolog 0.0256 0.3398 0.6014
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0275 0.3687 0.5402
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0242 0.3179 0.4641
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0591
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0044 0.012 0.0131
Giardia lamblia 26S protease regulatory subunit 7 0.0037 0.0021 0.0031
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Echinococcus multilocularis proteasome (prosome, macropain) 0.0478 0.6826 0.6826
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0238 0.313 0.4585
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0058 0.034 0.0319
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5387
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0276 0.3715 0.3702
Loa Loa (eye worm) proteasome Regulatory Particle 0.0063 0.0416 0.0452
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0056 0.0309 0.0453
Trypanosoma brucei proteasome beta 7 subunit 0.0238 0.313 0.4585
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Schistosoma mansoni 26S proteasome subunit S9 0.007 0.0519 0.0498
Echinococcus granulosus proteasome subunit alpha type 2 0.0262 0.3498 0.3498
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.007 0.0519 0.0498
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0242 0.3179 0.4658
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0039 0.0038 0.0025
Echinococcus granulosus 26S protease regulatory subunit 8 0.0037 0.0021 0.0021
Schistosoma mansoni 26S protease regulatory subunit 0.0039 0.0038 0.0017
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0063 0.0419 0.0419
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0238 0.313 0.4585
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0055 0.0294 0.0401
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0231 0.3016 0.4402
Leishmania major proteasome beta 2 subunit, putative 0.0242 0.3179 0.4658
Echinococcus granulosus proteasome subunit beta type 7 0.0683 1 1
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0041 0.0072 0.0106
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0252 0.3335 0.3335
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0242 0.3179 0.4641
Brugia malayi Proteasome subunit alpha type 1 0.0221 0.2854 0.2839
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0058 0.034 0.0468
Entamoeba histolytica proteasome regulatory subunit, putative 0.0075 0.06 0.085
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0252 0.3335 0.3626
Entamoeba histolytica proteasome regulatory subunit, putative 0.0041 0.0072 0.0074
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0063 0.0416 0.0416
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0275 0.3687 0.3994
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0478 0.6826 1
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Brugia malayi PCI domain containing protein 0.0063 0.0419 0.0399
Toxoplasma gondii proteasome beta subunit 0.0242 0.3179 0.3441
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0058 0.0335 0.0491
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Echinococcus granulosus proteasome prosome macropain 0.0478 0.6826 0.6826
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0191 0.2393 0.5
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0055 0.0294 0.0294
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0275 0.3687 0.3674
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0037 0.0021 0.0031
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0063 0.0416 0.0416
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0254 0.3363 0.4927
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0276 0.3715 0.4039
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0262 0.3498 0.3803
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0041 0.0072 0.0106
Brugia malayi proteasome subunit alpha type 6 0.0276 0.3715 0.3702
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0294 0.3994 0.5852
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0041 0.0074 0.0108
Echinococcus granulosus proteasome subunit beta type 6 0.0254 0.3363 0.3363
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.005 0.0217 0.0317
Entamoeba histolytica proteasome regulatory subunit, putative 0.0063 0.0419 0.0585
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0231 0.3016 0.3279
Echinococcus granulosus adhesion regulating molecule 1 0.0631 0.9198 0.9198
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0037 0.0021 0.0031
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.007 0.0519 0.076
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0041 0.0074 0.0077
Trypanosoma brucei proteasome alpha 7 subunit 0.0256 0.3398 0.4979
Leishmania major proteasome alpha 1 subunit, putative 0.0252 0.3335 0.4887
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0231 0.3016 0.4402
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0025
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0347 0.4808 0.7035
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Schistosoma mansoni hypothetical protein 0.0058 0.0335 0.0314
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0058 0.034 0.0319
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0262 0.3498 0.3484
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0058 0.034 0.0319
Brugia malayi Proteasome subunit alpha type 7-1 0.0347 0.4808 0.4797
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0074 0.0591 0.0837
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0039 0.0038 0.0038
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0063 0.0416 0.0609
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.007 0.0519 0.076
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0074 0.0591 0.0866
Leishmania major proteasome beta 7 subunit, putative 0.0238 0.313 0.4585
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0037 0.0021 0.0031
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0591
Giardia lamblia 26S protease regulatory subunit 6A 0.0041 0.0074 0.0108
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0294 0.3994 0.5839
Plasmodium falciparum proteasome subunit beta type-4 0.0238 0.313 0.4568
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0253 0.335 0.4908
Loa Loa (eye worm) hypothetical protein 0.0051 0.0229 0.0248
Echinococcus multilocularis proteasome subunit beta type 6 0.0254 0.3363 0.3363
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0242 0.3179 0.4641
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Brugia malayi Ubiquitin interaction motif family protein 0.0041 0.0072 0.0051
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.0039 0.0038 0.0056
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0276 0.3715 0.5443
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0041
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0041 0.0074 0.008
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Trypanosoma cruzi 20S proteasome subunit 0.0242 0.3179 0.4658
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0254 0.3363 0.3656
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0041 0.0074 0.0108
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0041 0.0074 0.0057
Loa Loa (eye worm) proteasome regulatory particle 0.007 0.0519 0.0564
Toxoplasma gondii heat shock protein hslv, putative 0.0191 0.2393 0.2585
Echinococcus granulosus proteasome subunit beta t family 0.0242 0.3179 0.3179
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0253 0.335 0.4892
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0347 0.4808 0.7035
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0253 0.335 0.335
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0055 0.0294 0.0431
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0063 0.0416 0.0609
Leishmania major proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0058 0.034 0.034
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0231 0.3016 0.4419
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0253 0.335 0.335
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0055 0.0294 0.0294
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0075 0.06 0.058
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.0098 0.0962 0.1383
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.007 0.0519 0.0731
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0038 0.0056
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0041 0.0074 0.0074
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Entamoeba histolytica proteasome regulatory subunit, putative 0.007 0.0519 0.0731
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0253 0.335 0.4892
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0075 0.06 0.06
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0037 0.0021 0.0021
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0275 0.3687 0.5387
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0038 0.0056
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0058 0.034 0.034
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0055 0.0294 0.0431
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0058 0.0335 0.0491
Giardia lamblia Proteasome subunit beta type 2 0.0242 0.3179 0.4658
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0238 0.313 0.3115
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0037 0.0021 0.0031
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0191 0.2393 0.3506
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.007 0.0519 0.076
Brugia malayi PCI domain containing protein 0.0058 0.0335 0.0314
Toxoplasma gondii PCI domain-containing protein 0.0075 0.06 0.0631
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0238 0.313 0.313
Giardia lamblia 20S proteasome alpha subunit 2 0.0262 0.3498 0.5124
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0191 0.2393 0.3506
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0222 0.2875 0.4211
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0037 0.0021 0.0023
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.007 0.0519 0.076
Echinococcus granulosus Proteasome subunit alpha type 7 0.0347 0.4808 0.4808
Brugia malayi Proteasome A-type and B-type family protein 0.0254 0.3363 0.3349
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0242 0.3179 0.3179
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0074 0.0591 0.0866
Schistosoma mansoni proteasome regulatory subunit-related 0.0063 0.0419 0.0399
Echinococcus multilocularis proteasome subunit alpha type 2 0.0262 0.3498 0.3498
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0055 0.0294 0.0273
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0058 0.034 0.0468
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Loa Loa (eye worm) proteasome 26S subunit 0.0037 0.0021 0.0023
Toxoplasma gondii proteasome subunit beta type, putative 0.0478 0.6826 0.7414
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0253 0.335 0.4908
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.313 0.3402
Loa Loa (eye worm) hypothetical protein 0.0411 0.5795 0.63
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0041 0.0074 0.0108
Leishmania major proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0347 0.4808 0.7045
Loa Loa (eye worm) hypothetical protein 0.0055 0.0294 0.032
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0058 0.034 0.034
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0074 0.0591 0.0571
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0294 0.3994 0.5852
Brugia malayi Proteasome/cyclosome repeat family protein 0.0044 0.012 0.0099
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0058 0.034 0.0497
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0243 0.3206 0.3191
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0329 0.4524 0.6617
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0242 0.3179 0.4658
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0238 0.313 0.4585
Brugia malayi proteasome subunit alpha type 4 0.0222 0.2869 0.2854
Giardia lamblia 20S proteasome alpha subunit 5 0.0275 0.3687 0.5402
Toxoplasma gondii SAC3/GANP family protein 0.0055 0.0294 0.0297
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Schistosoma mansoni multiubiquitin binding protein S5a 0.0041 0.0072 0.0051
Onchocerca volvulus 0.0039 0.0038 0.003
Leishmania major proteasome alpha 7 subunit, putative 0.0256 0.3398 0.4979
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0063 0.0419 0.0434
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0231 0.3016 0.4419
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0063 0.0416 0.0609
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0262 0.3498 0.5124
Schistosoma mansoni hypothetical protein 0.0411 0.5795 0.5786
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0074 0.0591 0.0866
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.005 0.0217 0.0213
Toxoplasma gondii proteasome subunit alpha1, putative 0.0276 0.3715 0.4025
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0254 0.3363 0.4911
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.005 0.0217 0.0287
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0275 0.3687 0.4008
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0242 0.3179 0.4658
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0058 0.0335 0.0335
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0039 0.0038 0.0038
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0252 0.3335 0.4887
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0018
Plasmodium vivax proteasome subunit beta type-2, putative 0.0242 0.3179 0.4641
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.0039 0.0038 0.0056
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0478 0.6826 0.6819
Echinococcus granulosus subfamily T1A non peptidase ue 0.0275 0.3687 0.3687
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0058 0.034 0.0468
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0041 0.0074 0.0074
Echinococcus multilocularis proteasome subunit beta type 7 0.0683 1 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0231 0.3016 0.4419
Loa Loa (eye worm) RPN-3 protein 0.0075 0.06 0.0652
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0254 0.3363 0.4927
Giardia lamblia 26S protease regulatory subunit 6B 0.0039 0.0038 0.0056
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0242 0.3179 0.4658
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0075 0.06 0.058
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0055 0.0294 0.0273
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0231 0.3016 0.4419
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0041 0.0074 0.0077
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0256 0.3398 0.4963
Loa Loa (eye worm) hypothetical protein 0.0631 0.9198 1
Toxoplasma gondii proteasome subunit 0.0254 0.3363 0.3641
Leishmania major proteasome beta 5 subunit, putative 0.0478 0.6826 1
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0242 0.3179 0.3179
Echinococcus multilocularis proteasome subunit alpha type 6 0.0276 0.3715 0.3715
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0058 0.034 0.0347
Entamoeba histolytica proteasome regulatory subunit, putative 0.0055 0.0294 0.0401
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0037 0.0021 0.0031
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0058 0.034 0.034
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0191 0.2393 0.3506
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0191 0.2393 0.3486
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0294 0.3994 0.3981
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0478 0.6826 1
Giardia lamblia Proteasome subunit beta type 3 0.0242 0.3179 0.4658
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0037 0.0021 0.0031
Trypanosoma brucei proteasome beta 6 subunit 0.0294 0.3994 0.5852
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0478 0.6826 1
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0063 0.0419 0.0614
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.0039 0.0038 0.0056
Loa Loa (eye worm) proteasome subunit beta type 2 0.0242 0.3179 0.3456
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0041 0.0072 0.0072
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0074 0.0591 0.0571
Brugia malayi Probable 26S protease regulatory subunit 4 0.0039 0.0038 0.0017
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0347 0.4808 0.7045
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0276 0.3715 0.5429
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0058 0.034 0.0369
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0039 0.0038 0.0056
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0347 0.4808 0.4797
Onchocerca volvulus 0.0039 0.0038 0.003
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0252 0.3335 0.3335
Loa Loa (eye worm) proteasome subunit beta type 1 0.0294 0.3994 0.4342
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0039 0.0038 0.0025
Giardia lamblia Hypothetical protein 0.007 0.0519 0.076
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0478 0.6826 1
Echinococcus multilocularis adhesion regulating molecule 1 0.0631 0.9198 0.9198
Loa Loa (eye worm) PCI domain-containing protein 0.0063 0.0419 0.0456
Brugia malayi Proteasome/cyclosome repeat family protein 0.0044 0.012 0.0099
Plasmodium vivax proteasome subunit beta type-3, putative 0.0242 0.3179 0.4641
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0242 0.3179 0.4641
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Loa Loa (eye worm) hypothetical protein 0.0037 0.0021 0.0023
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0294 0.3994 0.3994
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0401 0.5636 1
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0098 0.0962 0.141
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0074 0.0591 0.0837
Plasmodium vivax proteasome subunit beta type-7, putative 0.0231 0.3016 0.4402
Giardia lamblia 20S proteasome alpha subunit 3 0.0253 0.335 0.4908
Toxoplasma gondii PCI domain-containing protein 0.0058 0.0335 0.0342
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0256 0.3398 0.3695
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0262 0.3498 0.5109
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0042
Entamoeba histolytica hypothetical protein 0.005 0.0217 0.0287
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0063 0.0416 0.0395
Entamoeba histolytica proteasome regulatory subunit, putative 0.0058 0.0335 0.0461
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0063 0.0416 0.0395
Leishmania major hypothetical protein, conserved 0.0329 0.4524 0.6628
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0262 0.3498 0.3788
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0262 0.3498 0.5109
Giardia lamblia 20S proteasome alpha subunit 4 0.0347 0.4808 0.7045
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0191 0.2393 0.2377
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0075 0.06 0.06
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0058 0.0335 0.0491
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0276 0.3715 0.5443
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0063 0.0419 0.0614
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.007 0.0519 0.0519
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0063 0.0419 0.0419
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0191 0.2393 0.3486
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0039 0.0038 0.0017
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0275 0.3687 0.5402
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0254 0.3363 0.3349
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0041 0.0073 0.0107
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0039 0.0038 0.0025
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.007 0.0519 0.0731
Brugia malayi proteasome subunit alpha type 2 0.0262 0.3498 0.3484
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0256 0.3398 0.3398
Echinococcus granulosus proteasome subunit alpha type 6 0.0276 0.3715 0.3715
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0256 0.3398 0.4963
Loa Loa (eye worm) proteasome subunit beta type 3 0.0242 0.3179 0.3456
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0231 0.3016 0.3264
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0238 0.313 0.313
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0058 0.0335 0.0335

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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