Detailed information for compound 1551299

Basic information

Technical information
  • TDR Targets ID: 1551299
  • Name: (2S)-1-[[(2R,3R)-2,4-dimethyl-3-(phenylmethox y)pentylidene]amino]oxy-3-(furan-2-ylmethoxy) propan-2-ol
  • MW: 389.485 | Formula: C22H31NO5
  • H donors: 1 H acceptors: 1 LogP: 3.39 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H](CO/N=C/[C@H]([C@@H](C(C)C)OCc1ccccc1)C)COCc1ccco1
  • InChi: 1S/C22H31NO5/c1-17(2)22(27-13-19-8-5-4-6-9-19)18(3)12-23-28-15-20(24)14-25-16-21-10-7-11-26-21/h4-12,17-18,20,22,24H,13-16H2,1-3H3/b23-12+/t18-,20+,22-/m1/s1
  • InChiKey: BGSGDWJKMVQQEV-YCUSJJLESA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-1-[[(2R,3R)-2,4-dimethyl-3-(phenylmethoxy)pentylidene]amino]oxy-3-(2-furylmethoxy)propan-2-ol
  • (2S)-1-[[(2R,3R)-3-(benzyloxy)-2,4-dimethyl-pentylidene]amino]oxy-3-(2-furylmethoxy)propan-2-ol
  • CMLD2_000765
  • CMLDBU00002242

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0179 0.1008 0.0128
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0227 0.1317 0.3293
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0054 0.0201 0.0214
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0257 0.0706
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0236 0.1379 0.1679
Plasmodium vivax proteasome subunit beta type-5, putative 0.0448 0.2752 1
Schistosoma mansoni cpg binding protein 0.0029 0.0038 0.0095
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0224 0.1298 0.4706
Echinococcus granulosus acetylcholinesterase 0.0141 0.0763 0.1908
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0362 0.0441
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.024 0.1404 0.1499
Onchocerca volvulus 0.0096 0.0467 0.0498
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0036 0.0082 0.0298
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0059 0.0232 0.0824
Onchocerca volvulus 0.1469 0.9365 1
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0224 0.1298 0.4717
Loa Loa (eye worm) carboxylesterase 0.0141 0.0763 0.093
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0079 0.0362 0.1298
Loa Loa (eye worm) carboxylesterase 0.0024 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0257 0.0642
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0038 0.0096 0.033
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0035 0.0075 0.0254
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0035 0.0075 0.0254
Trypanosoma cruzi 20S proteasome subunit 0.0227 0.1317 0.4777
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0079 0.0362 0.0905
Echinococcus multilocularis carboxylesterase 5A 0.0141 0.0763 0.0763
Brugia malayi CHD4 protein 0.0025 0.001 0.0012
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0065 0.0271 0.0966
Schistosoma mansoni cpg binding protein 0.0029 0.0038 0.0095
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0258 0.1517 0.5505
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0052 0.0183 0.0195
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0054 0.0201 0.0729
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.007 0.0303 0.1083
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0918 0.1118
Schistosoma mansoni gliotactin 0.0024 0.0003 0.0006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0193 0.11 0.0478
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0059 0.0232 0.0843
Trichomonas vaginalis glutaminase, putative 0.0274 0.1622 0.1732
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.001 0.0026
Mycobacterium tuberculosis Possible formate hydrogenlyase HycD (FHL) 0.0039 0.0098 0.0265
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0257 0.0915
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0054 0.0199 0.0722
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0019 0.0049
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0054 0.0201 0.071
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Brugia malayi NADH dehydrogenase subunit 1, identical 0.0039 0.0098 0.012
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0034 0.0067 0.0224
Schistosoma mansoni lipoxygenase 0.0058 0.0224 0.0561
Plasmodium falciparum glutathione reductase 0.0076 0.0342 0.1242
Entamoeba histolytica proteasome regulatory subunit, putative 0.007 0.0303 0.0402
Leishmania major proteasome beta 2 subunit, putative 0.0227 0.1317 0.4777
Schistosoma mansoni 26S protease regulatory subunit S10b 0.0035 0.0075 0.0189
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0217 0.1253 0.4544
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0036 0.0082 0.0109
Brugia malayi proteasome subunit alpha type 1 0.0236 0.1379 0.1679
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0038 0.0095 0.0327
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0448 0.2752 1
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.007 0.0303 0.0758
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0036 0.0082 0.0088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0049
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0038 0.0096 0.033
Toxoplasma gondii PCI domain-containing protein 0.007 0.0303 0.1101
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0174 0.0975 0.2698
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.005 0.0172 0.0625
Onchocerca volvulus 0.0036 0.0082 0.0088
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0036 0.0082 0.0298
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0038 0.0095 0.0102
Giardia lamblia 26S protease regulatory subunit 8 0.0035 0.0075 0.0075
Trypanosoma brucei proteasome alpha 7 subunit 0.024 0.1404 0.5091
Loa Loa (eye worm) hypothetical protein 0.0079 0.0362 0.0441
Leishmania major proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Toxoplasma gondii thioredoxin reductase 0.0076 0.0342 0.1242
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0052 0.0183 0.0645
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0019 0.0049
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0034 0.0067 0.0224
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0036 0.0082 0.0298
Trypanosoma brucei glucosidase, putative 0.0037 0.0085 0.029
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0019
Onchocerca volvulus 0.0063 0.0256 0.0274
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.0003 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Echinococcus multilocularis jumonji domain containing 1A 0.0079 0.0362 0.0362
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Leishmania major proteasome beta 2 subunit, putative 0.0217 0.1253 0.4544
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.0036 0.0082 0.0084
Plasmodium vivax proteasome subunit beta type-1, putative 0.0276 0.1638 0.5953
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0052 0.0183 0.0457
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.024 0.1404 0.5091
Schistosoma mansoni gabp alpha 0.0075 0.0336 0.0839
Giardia lamblia 26S proteasome regulatory subunit, putative 0.0032 0.0058 0.0052
Toxoplasma gondii proteasome subunit 0.0238 0.139 0.5051
Loa Loa (eye worm) PAS-3 protein 0.0208 0.1195 0.1456
Brugia malayi proteasome subunit alpha type 2 0.0246 0.1443 0.1757
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0448 0.2752 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0081 0.0372 0.0372
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Giardia lamblia 20S proteasome alpha subunit 7 0.024 0.1404 0.1841
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0085 0.029
Schistosoma mansoni lamin 0.0028 0.0029 0.0074
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0236 0.1379 0.1379
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0036 0.0082 0.0088
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0298 0.1065
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0054 0.0201 0.0244
Plasmodium vivax hypothetical protein, conserved 0.0148 0.0806 0.293
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0157 0.0866 0.0866
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0079 0.0362 0.1298
Toxoplasma gondii proteasome beta subunit 0.0227 0.1317 0.4788
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0966 0.1031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0233 0.0845
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0054 0.0201 0.0244
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0257 0.0257
Echinococcus granulosus JmjC domain containing protein 4 0.0079 0.0362 0.0905
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0507 0.0617
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0343 0.2071 0.7525
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0179 0.1008 0.3665
Toxoplasma gondii tat-binding family protein, putative 0.0035 0.0075 0.0274
Echinococcus multilocularis survival motor neuron protein 1 0.0477 0.2936 0.2936
Brugia malayi Probable 26S protease regulatory subunit 4 0.0036 0.0082 0.01
Plasmodium vivax proteasome subunit beta type-2, putative 0.0227 0.1317 0.4788
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1187 0.7539 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0153 0.0382
Plasmodium vivax SET domain protein, putative 0.0186 0.1051 0.3819
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0326 0.1958 0.1958
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0448 0.2752 0.3634
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0448 0.2752 0.365
Trichomonas vaginalis chromobox protein, putative 0.0143 0.0777 0.083
Onchocerca volvulus 0.0209 0.1203 0.1284
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0408 0.2494 0.2494
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0918 0.0918
Schistosoma mansoni alpha glucosidase 0.0037 0.0085 0.0213
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0298 0.0396
Onchocerca volvulus 0.0028 0.0028 0.003
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0224 0.1298 0.3245
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.007 0.0299 0.032
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0258 0.1517 0.2013
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0038 0.0096 0.024
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0408 0.0436
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0179 0.1008 0.2792
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0036 0.0082 0.0205
Brugia malayi 20S proteasome alpha5 subunit 0.0258 0.1517 0.1848
Onchocerca volvulus 0.0039 0.0098 0.0105
Schistosoma mansoni hypothetical protein 0.0054 0.0199 0.0497
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0217 0.1253 0.1663
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0054 0.0201 0.0729
Schistosoma mansoni hypothetical protein 0.0102 0.0507 0.1267
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0227 0.1317 0.3293
Loa Loa (eye worm) hypothetical protein 0.008 0.0369 0.0449
Onchocerca volvulus 0.0028 0.0029 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0257 0.0706
Trichomonas vaginalis 26S proteasome subunit, putative 0.0054 0.0199 0.0212
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Echinococcus granulosus dnaJ subfamily B 0.0395 0.2408 0.602
Plasmodium vivax proteasome subunit beta type-3, putative 0.0227 0.1317 0.4788
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0246 0.1443 0.1914
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0326 0.1958 0.7117
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Echinococcus granulosus survival motor neuron protein 1 0.0477 0.2936 0.734
Onchocerca volvulus 0.0039 0.0098 0.0105
Plasmodium falciparum proteasome subunit beta type-5 0.0448 0.2752 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0257 0.0706
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0038 0.0096 0.0096
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0276 0.1638 0.1749
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Brugia malayi Proteasome A-type and B-type family protein 0.0238 0.139 0.1693
Echinococcus granulosus jumonji domain containing 1A 0.0079 0.0362 0.0905
Echinococcus granulosus lamin 0.0028 0.0029 0.0074
Brugia malayi Ubiquitin interaction motif family protein 0.0038 0.0095 0.0116
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.0019 0.0046
Plasmodium vivax proteasome subunit alpha type-3, putative 0.024 0.1404 0.5101
Loa Loa (eye worm) acetylcholinesterase 1 0.0141 0.0763 0.093
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0034 0.0067 0.0072
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0326 0.1958 0.7117
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0006 0.0021
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0059 0.0231 0.0246
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0035 0.0075 0.0092
Echinococcus granulosus proteasome subunit beta type 6 0.0238 0.139 0.3474
Brugia malayi proteasome subunit beta type 3 0.0227 0.1317 0.1605
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0038 0.0096 0.033
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0029 0.0036
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0052 0.0183 0.0645
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0019 0.0069
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0298 0.0363
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0054 0.0199 0.0703
Leishmania major proteasome alpha 1 subunit, putative 0.0236 0.1379 0.5001
Echinococcus multilocularis Proteasome, subunit alpha beta 0.024 0.1404 0.1404
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0054 0.0201 0.0729
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0032
Echinococcus multilocularis PHD finger protein rhinoceros 0.0148 0.0806 0.0806
Plasmodium falciparum 26S protease regulatory subunit 10B, putative 0.0035 0.0075 0.0274
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5505
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0036 0.0082 0.0278
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0186 0.1051 0.1051
Echinococcus granulosus peregrin 0.0148 0.0806 0.2016
Brugia malayi hypothetical protein 0.0024 0.0003 0.0003
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0047 0.0152 0.038
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0259 0.1528 0.1861
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0259 0.1528 0.5554
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0157 0.0866 0.2164
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.022 0.022
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0034 0.0067 0.0072
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0085 0.0091
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0035 0.0075 0.0075
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.058 0.3605 1
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0059 0.0232 0.0232
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0218 0.1259 0.1344
Echinococcus multilocularis cpg binding protein 0.0029 0.0038 0.0038
Schistosoma mansoni alpha-glucosidase 0.0142 0.0769 0.1923
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0249 0.1464 0.1784
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Loa Loa (eye worm) hypothetical protein 0.0148 0.0806 0.0982
Schistosoma mansoni hypothetical protein 0.0395 0.2408 0.602
Plasmodium falciparum phd finger protein, putative 0.0148 0.0806 0.293
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0259 0.1528 0.1632
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0161 0.0566
Loa Loa (eye worm) hypothetical protein 0.0149 0.0812 0.0989
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0257 0.0642
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0047 0.0152 0.038
Giardia lamblia 20S proteasome alpha subunit 3 0.0237 0.1385 0.1816
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.007 0.0299 0.107
Mycobacterium tuberculosis Probable dehydrogenase 0.0174 0.0975 0.2698
Loa Loa (eye worm) heterochromatin protein 1 0.0143 0.0777 0.0947
Toxoplasma gondii peptidase, T1 family protein 0.024 0.1404 0.5101
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0048
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0041 0.0114 0.0122
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.0036 0.0082 0.0088
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0054 0.0199 0.0722
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0246 0.1443 0.5233
Loa Loa (eye worm) hypothetical protein 0.0186 0.1051 0.128
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0259 0.1528 0.2027
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0238 0.139 0.1823
Toxoplasma gondii proteasome subunit alpha type, putative 0.0237 0.1385 0.5032
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0227 0.1317 0.4788
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0006 0.0021
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0038 0.0096 0.0349
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0369 0.0394
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0054 0.0199 0.0703
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0059 0.0231 0.0281
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0054 0.0201 0.071
Leishmania major proteasome alpha 2 subunit, putative 0.0246 0.1443 0.5233
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0237 0.1385 0.1478
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0028 0.0034
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0035 0.0075 0.01
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.0003 0.0006
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0238 0.139 0.5051
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0038 0.0096 0.024
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.026 0.0317
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0259 0.1528 0.5554
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0174 0.0975 0.2698
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.01
Brugia malayi SET domain containing protein 0.0031 0.0048 0.0059
Trypanosoma brucei trypanothione reductase 0.0076 0.0342 0.1224
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0298 0.0363
Brugia malayi hypothetical protein 0.0039 0.0098 0.012
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0054 0.0201 0.0501
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0227 0.1317 0.1748
Toxoplasma gondii PHD-finger domain-containing protein 0.0148 0.0806 0.293
Loa Loa (eye worm) jmjC domain-containing protein 0.0305 0.1827 0.2225
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.007 0.0299 0.107
Toxoplasma gondii PHD-finger domain-containing protein 0.0148 0.0806 0.293
Schistosoma mansoni hypothetical protein 0.0493 0.3041 0.7602
Leishmania major proteasome beta 5 subunit, putative 0.0448 0.2752 1
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0054 0.0199 0.0703
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0038 0.0096 0.0128
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.007 0.0299 0.107
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0041 0.0114 0.0139
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0224 0.1298 0.1701
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.058 0.3605 1
Brugia malayi Proteasome subunit alpha type 7-1 0.0326 0.1958 0.2385
Giardia lamblia 20S proteasome alpha subunit 2 0.0246 0.1443 0.1893
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0812 0.0989
Onchocerca volvulus 0.0024 0.0003 0.0003
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0019 0.0069
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0036 0.0082 0.0278
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0966 0.1031
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0153 0.0153
Toxoplasma gondii proteasome regulatory subunit 0.0054 0.0201 0.0729
Brugia malayi Proteasome A-type and B-type family protein 0.0448 0.2752 0.3351
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0336 0.0839
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0179 0.1008 0.2521
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0386 0.2346 0.2857
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.024 0.1404 0.1862
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0036 0.0082 0.0082
Brugia malayi proteasome subunit beta type 1 0.0276 0.1638 0.1995
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.0003 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0076 0.0342 0.1224
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0217 0.0231
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.0161 0.0586
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase subunit H 0.0144 0.0778 0.7669
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0641 0.4 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0224 0.0224
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0298 0.1065
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0038 0.0095 0.0238
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0059 0.0231 0.0231
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0035 0.0075 0.0254
Brugia malayi 26S proteasome subunit P45 family protein 0.0036 0.0082 0.01
Plasmodium vivax glutathione reductase, putative 0.0076 0.0342 0.1242
Plasmodium falciparum 26S proteasome regulatory subunit RPN10, putative 0.0025 0.001 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0038 0.0096 0.033
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0054 0.0201 0.0244
Plasmodium falciparum JmjC domain-containing protein, putative 0.0079 0.0362 0.1316
Schistosoma mansoni phosphatidylserine receptor 0.0079 0.0362 0.0905
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.031
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0448 0.2752 0.2938
Leishmania major hypothetical protein, conserved 0.0179 0.1006 0.3642
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0029 0.0036
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.007 0.0303 0.1083
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0019 0.0049
Brugia malayi Proteasome/cyclosome repeat family protein 0.0041 0.0114 0.0139
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0298 0.1065
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0179 0.1008 0.3652
Brugia malayi Ets-domain containing protein 0.0075 0.0336 0.0409
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0049
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0918 0.1118
Schistosoma mansoni hypothetical protein 0.0048 0.0161 0.0403
Loa Loa (eye worm) hypothetical protein 0.0079 0.0362 0.0441
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0059 0.0231 0.0838
Brugia malayi jmjC domain containing protein 0.0603 0.3755 0.4573
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.001 0.0026
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0035 0.0075 0.0254
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Mycobacterium tuberculosis Probable reductase 0.0174 0.0975 0.2698
Brugia malayi hypothetical protein 0.0477 0.2936 0.3576
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0019 0.0049
Schistosoma mansoni protein phosphatase 2C 0.0079 0.0362 0.0905
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0019 0.0069
Echinococcus granulosus 26S protease regulatory subunit 8 0.0035 0.0075 0.0189
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0224 0.1298 0.1298
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0054 0.0201 0.0244
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0257 0.0642
Loa Loa (eye worm) PCI domain-containing protein 0.0054 0.0199 0.0242
Loa Loa (eye worm) proteasome subunit alpha type 3 0.024 0.1404 0.171
Plasmodium falciparum proteasome subunit beta type-4 0.0224 0.1298 0.4717
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0257 0.0706
Loa Loa (eye worm) proteasome Regulatory Particle 0.0059 0.0231 0.0281
Echinococcus granulosus histone lysine methyltransferase setb 0.0186 0.1051 0.2627
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0153 0.0186
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.007 0.0299 0.0299
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0059 0.0231 0.0576
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0298 0.0745
Giardia lamblia 20S proteasome alpha subunit 4 0.0326 0.1958 0.2579
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0059 0.0231 0.0819
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0174 0.0975 0.2698
Echinococcus multilocularis chromobox protein 1 0.0143 0.0777 0.0777
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0918 0.2295
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0153 0.0186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0186 0.1051 0.2627
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0029 0.0036
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0087 0.0408 0.0436
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5505
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0038 0.0096 0.0117
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0065 0.0271 0.0966
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0812 0.0989
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0273 0.0683
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.001 0.001
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0047 0.0152 0.0152
Loa Loa (eye worm) proteasome subunit beta type 3 0.0227 0.1317 0.1605
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Loa Loa (eye worm) proteasome 26S subunit 0.0035 0.0075 0.0092
Echinococcus granulosus thioredoxin glutathione reductase 0.0077 0.0348 0.0871
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0362 0.0441
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0054 0.0201 0.071
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.0003 0.0006
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0246 0.1443 0.5243
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0276 0.1638 0.5945
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1187 0.7539 1
Loa Loa (eye worm) hypothetical protein 0.0141 0.0763 0.093
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0224 0.0561
Echinococcus granulosus proteasome subunit alpha type 6 0.0259 0.1528 0.3821
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0085 0.0104
Brugia malayi glutathione reductase 0.0076 0.0342 0.0416
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0343 0.2071 0.2522
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0052 0.0183 0.0645
Loa Loa (eye worm) thioredoxin reductase 0.0076 0.0342 0.0416
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0237 0.1385 0.5032
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0227 0.1317 0.1317
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Schistosoma mansoni acetylcholinesterase 0.0024 0.0003 0.0006
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0179 0.1008 1
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0036 0.0082 0.0109
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0227 0.1317 0.4777
Giardia lamblia 20S proteasome alpha subunit 5 0.0258 0.1517 0.1992
Toxoplasma gondii SAC3/GANP family protein 0.0052 0.0183 0.0664
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0326 0.1958 0.1958
Toxoplasma gondii proteasome 26S regulatory subunit 0.0037 0.0089 0.0323
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0603 0.3755 0.9387
Plasmodium vivax proteasome subunit beta type-4, putative 0.0224 0.1298 0.4717
Echinococcus granulosus geminin 0.0493 0.3041 0.7602
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0179 0.1008 0.3652
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0035 0.0075 0.0254
Brugia malayi Proteasome A-type and B-type family protein 0.0641 0.4 0.4872
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0191
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0038 0.0095 0.0238
Brugia malayi Cytochrome P450 family protein 0.0031 0.005 0.006
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0237 0.1385 0.3462
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0034 0.0067 0.0224
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0478 0.0582
Giardia lamblia 26S protease regulatory subunit 6A 0.0038 0.0096 0.0103
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Loa Loa (eye worm) glutathione reductase 0.0076 0.0342 0.0416
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.007 0.0299 0.1088
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.022 0.0268
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0038 0.0096 0.0102
Loa Loa (eye worm) hypothetical protein 0.0285 0.1696 0.2065
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0217 0.1253 0.1527
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0079 0.0362 0.1298
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.0003 0.0003
Schistosoma mansoni multiubiquitin binding protein S5a 0.0038 0.0095 0.0238
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.0036 0.0082 0.0278
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0237 0.1385 0.1385
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0054 0.0201 0.0729
Schistosoma mansoni hypothetical protein 0.0157 0.0866 0.2164
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0019 0.0049
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0034 0.0067 0.0072
Brugia malayi PHD-finger family protein 0.0148 0.0806 0.0982
Treponema pallidum fructose-bisphosphate aldolase 0.1187 0.7539 1
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0065 0.0271 0.0966
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0237 0.1385 0.1837
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0276 0.1638 0.4095
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0193 0.11 0.3048
Loa Loa (eye worm) PCI domain-containing protein 0.0059 0.0232 0.0283
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.022 0.055
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.005 0.006
Schistosoma mansoni hypothetical protein 0.0097 0.0478 0.1194
Toxoplasma gondii heat shock protein hslv, putative 0.0179 0.1008 0.3665
Loa Loa (eye worm) hypothetical protein 0.0047 0.0153 0.0186
Giardia lamblia 26S protease regulatory subunit 6B 0.0036 0.0082 0.0084
Loa Loa (eye worm) glutaminase 2 0.0274 0.1622 0.1975
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0065 0.0271 0.0985
Echinococcus multilocularis thioredoxin glutathione reductase 0.0077 0.0348 0.0348
Loa Loa (eye worm) hypothetical protein 0.0063 0.0256 0.0312
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0054 0.0201 0.0201
Mycobacterium ulcerans formate hydrogenlyase HycD 0.0039 0.0098 0.0265
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0036 0.0082 0.0278
Schistosoma mansoni proteasome regulatory subunit-related 0.0059 0.0232 0.058
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0059 0.0231 0.0819
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0006 0.0021
Echinococcus granulosus intermediate filament protein 0.0028 0.0029 0.0074
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0054 0.0201 0.0201
Echinococcus granulosus NADH dehydrogenase subunit 1 0.0144 0.0778 0.1944
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0448 0.2752 0.3351
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0343 0.2071 0.5177
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.022 0.055
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.0053 0.0194 0.0705
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0603 0.3755 0.3755
Brugia malayi PCI domain containing protein 0.0054 0.0199 0.0242
Echinococcus granulosus Proteasome subunit alpha beta 0.024 0.1404 0.3509
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0036 0.0082 0.0298
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0326 0.1958 0.2598
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0161 0.0566
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0038 0.0096 0.024
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0408 0.2494 0.6235
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0047 0.0152 0.0553
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.022 0.0781
Brugia malayi Fli-1 protein 0.0229 0.1329 0.1618
Echinococcus multilocularis JmjC domain containing protein 4 0.0079 0.0362 0.0362
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0179 0.1006 0.3655
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.2408 0.2408
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.024 0.1404 0.5101
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0054 0.0199 0.0199
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.007 0.0299 0.0373
Echinococcus granulosus neuroligin 0.0024 0.0003 0.0006
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0035 0.0075 0.0075
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0186 0.1051 0.1051
Plasmodium falciparum glutathione reductase 0.0026 0.0019 0.0069
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 10 0.0025 0.001 0.0015
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Loa Loa (eye worm) hypothetical protein 0.0052 0.0183 0.0223
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0038 0.0095 0.0095
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0052 0.0183 0.0223
Onchocerca volvulus 0.0024 0.0003 0.0003
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0237 0.1385 0.3462
Leishmania major trypanothione reductase 0.0076 0.0342 0.1224
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.01
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0227 0.1317 0.1407
Loa Loa (eye worm) PHD-finger family protein 0.0148 0.0806 0.0982
Brugia malayi Pre-SET motif family protein 0.0186 0.1051 0.128
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.007 0.0303 0.0369
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0236 0.1379 0.1472
Giardia lamblia Non ATPase subunit MPR1 of 26S proteasome 0.0034 0.0067 0.0064
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0052 0.0183 0.0183
Loa Loa (eye worm) proteasome subunit beta type 1 0.0276 0.1638 0.1995
Brugia malayi 26S proteasome subunit-like protein 0.0025 0.001 0.0012
Brugia malayi Proteasome/cyclosome repeat family protein 0.0041 0.0114 0.0139
Echinococcus multilocularis lysine specific demethylase 6a 0.0079 0.0362 0.0362
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0217 0.1253 0.4544
Loa Loa (eye worm) hypothetical protein 0.0477 0.2936 0.3576
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0195 0.0238
Plasmodium vivax hypothetical protein, conserved 0.005 0.0172 0.0625
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0227 0.1317 0.1407
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0326 0.1958 0.2598
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0193 0.11 0.3048
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0085 0.0091
Echinococcus granulosus Proteasome subunit alpha type 7 0.0326 0.1958 0.4895
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0153 0.0153
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0035 0.0075 0.0081
Toxoplasma gondii proteasome subunit alpha type, putative 0.0147 0.0798 0.2899
Giardia lamblia Hypothetical protein 0.0065 0.0271 0.0335
Brugia malayi proteasome subunit alpha type 4 0.0208 0.1195 0.1456
Schistosoma mansoni lamin 0.0028 0.0029 0.0074
Echinococcus granulosus lamin dm0 0.0028 0.0029 0.0074
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0362 0.0441
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) 0.0144 0.0778 0.2152
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0326 0.1958 0.4895
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0271 0.036
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0019 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Giardia lamblia 20S proteasome alpha subunit 1 0.0259 0.1528 0.2007
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0036 0.0082 0.0082
Echinococcus multilocularis lamin dm0 0.0028 0.0029 0.0029
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0259 0.1528 0.3821
Echinococcus multilocularis proteasome subunit alpha type 2 0.0246 0.1443 0.1443
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.0003 0.0006
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0085 0.0213
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Giardia lamblia Fructose-bisphosphate aldolase 0.1187 0.7539 1
Leishmania major proteasome beta-1 subunit, putative 0.0238 0.139 0.504
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0298 0.0745
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0085 0.0091
Echinococcus multilocularis Chromobox protein 3 0.0023 0.000000050219 0.000000050219
Schistosoma mansoni chromobox protein 0.0143 0.0777 0.1943
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Schistosoma mansoni survival motor neuron protein 0.0097 0.0478 0.1194
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0227 0.1317 0.3293
Echinococcus granulosus jumonji domain containing protein 0.0206 0.1182 0.2954
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0035 0.0075 0.01
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0041 0.0043
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0246 0.1443 0.5243
Loa Loa (eye worm) proteasome subunit beta type 2 0.0227 0.1317 0.1605
Plasmodium vivax thioredoxin reductase, putative 0.0076 0.0342 0.1242
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0227 0.1317 0.4788
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0276 0.1638 0.4095
Echinococcus multilocularis proteasome (prosome, macropain) 0.0448 0.2752 0.2752
Echinococcus multilocularis cyclin 0.0028 0.0029 0.0029
Giardia lamblia Proteasome subunit beta type 2 0.0227 0.1317 0.1727
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0038 0.0096 0.0349
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0085 0.0085
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0059 0.0232 0.0824
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0079 0.0362 0.1316
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0019 0.0049
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0246 0.1443 0.5243
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0035 0.0075 0.01
Brugia malayi AF-10 protein 0.0048 0.0161 0.0196
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.007 0.0303 0.1101
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.139 0.1693
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0054 0.0201 0.0501
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0036 0.0082 0.0205
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0037 0.0089 0.0118
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0036 0.0082 0.0278
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.024 0.1404 0.1862
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0258 0.1517 0.5514
Echinococcus multilocularis jumonji domain containing protein 0.0206 0.1182 0.1182
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0059 0.0232 0.058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0003 0.0006
Onchocerca volvulus 0.0024 0.0003 0.0003
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.0909 0.097
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0059 0.0232 0.0843
Echinococcus granulosus PHD finger protein rhinoceros 0.0148 0.0806 0.2016
Echinococcus granulosus carboxylesterase 5A 0.0141 0.0763 0.1908
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0448 0.2752 0.6756
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0059 0.0231 0.0281
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0258 0.1517 0.3793
Loa Loa (eye worm) RPN-3 protein 0.007 0.0303 0.0369
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0049
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0036 0.0082 0.0278
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0052 0.0183 0.0664
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.022 0.0604
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0054 0.0199 0.0497
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0326 0.1958 0.1958
Schistosoma mansoni chromobox protein 0.0143 0.0777 0.1943
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0059 0.0232 0.0248
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0276 0.1638 0.5945
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0236 0.1379 0.5001
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0448 0.2752 0.7632
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0019 0.0049
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0035 0.0075 0.0189
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0246 0.1443 0.1757
Brugia malayi Pre-SET motif family protein 0.1291 0.8211 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1291 0.8211 1
Brugia malayi 26S protease regulatory subunit 8 0.0035 0.0075 0.0092
Loa Loa (eye worm) NADH dehydrogenase subunit 1 0.0039 0.0098 0.012
Brugia malayi Bromodomain containing protein 0.0148 0.0806 0.0982
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Echinococcus granulosus lysine specific demethylase 6a 0.0079 0.0362 0.0905
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0236 0.1379 0.3447
Onchocerca volvulus 26S protease regulatory subunit 8 homolog 0.0035 0.0075 0.0081
Echinococcus multilocularis GPCR, family 2 0.0047 0.0153 0.0153
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0227 0.1317 0.1407
Schistosoma mansoni intermediate filament proteins 0.0028 0.0029 0.0074
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0153 0.0382
Brugia malayi MH2 domain containing protein 0.0134 0.0718 0.0875
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0236 0.1379 0.5011
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0298 0.1065
Entamoeba histolytica proteasome regulatory subunit, putative 0.0038 0.0095 0.0126
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0059 0.0231 0.0838
Plasmodium falciparum 26S protease regulatory subunit 8, putative 0.0035 0.0075 0.0274
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0179 0.1008 0.3652
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0336 0.0336
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Trypanosoma brucei proteasome beta 7 subunit 0.0224 0.1298 0.4706
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.0003 0.0006
Echinococcus multilocularis musashi 0.0028 0.0029 0.0029
Echinococcus multilocularis lysine specific demethylase 5A 0.0298 0.1776 0.1776
Echinococcus granulosus cpg binding protein 0.0029 0.0038 0.0095
Echinococcus multilocularis proteasome subunit alpha type 6 0.0259 0.1528 0.1528
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Schistosoma mansoni alpha-glucosidase 0.0142 0.0769 0.1923
Schistosoma mansoni jumonji/arid domain-containing protein 0.0299 0.1786 0.4465
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0276 0.1638 0.5945
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0238 0.139 0.1843
Brugia malayi proteasome subunit alpha type 3 0.024 0.1404 0.171
Echinococcus granulosus GPCR family 2 0.0047 0.0153 0.0382
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Brugia malayi PCI domain containing protein 0.0059 0.0232 0.0283
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0217 0.1253 0.4544
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0224 0.1298 0.1386
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0054 0.0199 0.0212
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.0113
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0052 0.0183 0.0664
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.007 0.0303 0.0303
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.001 0.0012
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0085 0.029
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0369 0.0394
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5514
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0085 0.0104
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5505
Echinococcus granulosus chromobox protein 1 0.0143 0.0777 0.1943
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0054 0.0201 0.0501
Loa Loa (eye worm) proteasome 26S subunit 0.0034 0.0067 0.0082
Loa Loa (eye worm) hypothetical protein 0.0035 0.0075 0.0092
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0276 0.1638 0.1638
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0227 0.1317 0.1317
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0208 0.1198 0.1279
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0227 0.1317 0.3293
Entamoeba histolytica hypothetical protein 0.0047 0.0152 0.0202
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0217 0.1253 0.1338
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0054 0.0201 0.0214
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0179 0.1008 0.3652
Toxoplasma gondii ubiquitin interaction motif family protein 0.0025 0.001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0141 0.0763 0.093
Toxoplasma gondii proteasome subunit alpha1, putative 0.0259 0.1528 0.5554
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0258 0.1517 0.3793
Leishmania major proteasome beta 7 subunit, putative 0.0224 0.1298 0.4706
Plasmodium falciparum thioredoxin reductase 0.0076 0.0342 0.1242
Loa Loa (eye worm) proteasome regulatory particle 0.0065 0.0271 0.033
Brugia malayi Probable 26S protease regulatory subunit S10B 0.0035 0.0075 0.0092
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0249 0.1464 0.1784
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0034 0.0067 0.0168
Echinococcus granulosus phd:f box containing protein 0.0079 0.0362 0.0905
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0034 0.0067 0.0067
Brugia malayi proteasome subunit beta type 2 0.0227 0.1317 0.1605
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Plasmodium falciparum thioredoxin reductase 0.0026 0.0019 0.0069
Mycobacterium ulcerans proteasome PrcB 0.0448 0.2752 0.7632
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0036 0.0082 0.0298
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0276 0.1638 0.5953
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0052 0.0183 0.0223
Loa Loa (eye worm) hypothetical protein 0.005 0.0171 0.0209
Echinococcus multilocularis phd:f box containing protein 0.0079 0.0362 0.0362
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0019 0.0069
Giardia lamblia 26S protease regulatory subunit 7 0.0035 0.0075 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0085 0.0091
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0258 0.1517 0.2013
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0052 0.0183 0.0195
Entamoeba histolytica proteasome regulatory subunit, putative 0.0054 0.0199 0.0264
Giardia lamblia Proteasome subunit beta type 3 0.0227 0.1317 0.1727
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0224 0.1298 0.1722
Brugia malayi NADH dehydrogenase subunit 1 0.0039 0.0098 0.012
Loa Loa (eye worm) hypothetical protein 0.0343 0.2071 0.2522
Echinococcus granulosus proteasome subunit beta type 7 0.0641 0.4 1
Echinococcus multilocularis acetylcholinesterase 0.0141 0.0763 0.0763
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.139 0.1484
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0038 0.0096 0.0349
Brugia malayi CXXC zinc finger family protein 0.0028 0.0028 0.0034
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0052 0.0183 0.0457
Loa Loa (eye worm) hypothetical protein 0.0386 0.2346 0.2857
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0236 0.1379 0.3447
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.0718 0.0875
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.007 0.0299 0.1088
Onchocerca volvulus 0.0024 0.0003 0.0003
Brugia malayi 26S proteasome regulatory complex subunit p97 0.007 0.0299 0.0365
Toxoplasma gondii PCI domain-containing protein 0.0065 0.0271 0.0985
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0059 0.0231 0.0838
Entamoeba histolytica proteasome regulatory subunit, putative 0.0059 0.0231 0.0306
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.007 0.0299 0.0748
Loa Loa (eye worm) hypothetical protein 0.0102 0.0507 0.0617
Echinococcus multilocularis peregrin 0.0148 0.0806 0.0806
Entamoeba histolytica proteasome regulatory subunit, putative 0.0059 0.0232 0.0308
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0258 0.1517 0.1848
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0217 0.1253 0.1338
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0023
Brugia malayi Carboxylesterase family protein 0.0141 0.0763 0.093
Brugia malayi intermediate filament protein 0.0028 0.0029 0.0036
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0448 0.2752 0.6879
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0258 0.1517 0.162
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.007 0.0303 0.1083
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0228 0.1328 0.332
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0037 0.0089 0.0303
Loa Loa (eye worm) carboxylesterase 0.0024 0.0003 0.0003
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0179 0.1008 0.3665
Toxoplasma gondii proteasome subunit beta type, putative 0.0448 0.2752 1
Plasmodium vivax 26S protease regulatory subunit 10B, putative 0.0035 0.0075 0.0274
Schistosoma mansoni hypothetical protein 0.0386 0.2346 0.5865
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0025 0.001 0.0011
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0326 0.1958 0.2091
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0812 0.0989
Echinococcus granulosus proteasome prosome macropain 0.0448 0.2752 0.6879
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.0036 0.0082 0.0278
Leishmania major hypothetical protein, conserved 0.0079 0.0362 0.1298
Echinococcus multilocularis lamin 0.0028 0.0029 0.0029
Onchocerca volvulus 0.0097 0.0478 0.051
Schistosoma mansoni jumonji domain containing protein 0.0503 0.311 0.7774
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0362 0.0905
Toxoplasma gondii hypothetical protein 0.0048 0.0157 0.057
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0224 0.1298 0.3245
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0227 0.1317 0.3293
Mycobacterium ulcerans proteasome PrcA 0.0179 0.1008 0.2792
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0047 0.0152 0.0553
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0053 0.0189 0.0667
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0076 0.0342 0.0942
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0217 0.1253 0.1642
Echinococcus multilocularis proteasome subunit beta type 6 0.0238 0.139 0.139
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0298 0.0298
Onchocerca volvulus 0.0023 0.000000050219 0.000000053622
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0065 0.0271 0.0289
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0052 0.0183 0.0195
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0047 0.0152 0.0553
Giardia lamblia Proteasome subunit beta type 1 0.0276 0.1638 0.2153
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0007
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0224 0.1298 0.1581
Giardia lamblia 20S proteasome alpha subunit 6 0.0236 0.1379 0.1808
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.024 0.1404 0.5091
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0019 0.0069
Brugia malayi Heterochromatin protein 1 0.0143 0.0777 0.0947
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0257 0.0933
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.007 0.0303 0.0758
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0059 0.0231 0.0576
Schistosoma mansoni phd/f-box containing protein 0.0079 0.0362 0.0905
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0237 0.1385 0.5032
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0019 0.0046
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0085 0.0091
Echinococcus granulosus transcription factor Dp 1 0.004 0.0109 0.0271
Loa Loa (eye worm) RPT-2 protein 0.0036 0.0082 0.01
Echinococcus granulosus cyclin 0.0028 0.0029 0.0073
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0153 0.0186
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0035 0.0075 0.0254
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0079 0.0362 0.1316
Schistosoma mansoni hypothetical protein 0.0493 0.3041 0.7602
Mycobacterium tuberculosis Probable oxidoreductase 0.0193 0.11 0.3048
Echinococcus granulosus proteasome subunit beta t family 0.0227 0.1317 0.3293
Onchocerca volvulus 0.0024 0.0003 0.0003
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0034 0.0067 0.0224
Plasmodium vivax JmjC domain containing protein 0.0079 0.0362 0.1316
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0217 0.1253 0.4555
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0179 0.1008 0.1338
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0059 0.0232 0.0824
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0054 0.0201 0.071
Leishmania major proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Echinococcus multilocularis neuroligin 0.0024 0.0003 0.0003
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0336 0.0409
Echinococcus granulosus acetylcholinesterase 0.0141 0.0763 0.1908
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0918 0.0918
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0065 0.0271 0.0985
Brugia malayi Proteasome subunit alpha type 1 0.0207 0.119 0.1449
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Brugia malayi Thioredoxin reductase 0.0076 0.0342 0.0416
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0227 0.1317 0.1748
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0186 0.1051 0.3819
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0408 0.2494 0.6235
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Echinococcus multilocularis geminin 0.0493 0.3041 0.3041
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0046
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0326 0.1958 0.2385
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0246 0.1443 0.5233
Onchocerca volvulus Heterochromatin protein 1 homolog 0.008 0.0369 0.0394
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0237 0.1385 0.1837
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0065 0.0271 0.0271
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0006 0.0021
Onchocerca volvulus Alhambra homolog 0.0148 0.0806 0.0861
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0236 0.1379 0.5011
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0227 0.1317 0.4777
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1464 0.1564
Schistosoma mansoni glutaminase 0.0274 0.1622 0.4054
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0038 0.0095 0.0327
Brugia malayi Proteasome A-type and B-type family protein 0.0224 0.1298 0.1581
Schistosoma mansoni hypothetical protein 0.0148 0.0806 0.2016
Leishmania major proteasome alpha 7 subunit, putative 0.0326 0.1958 0.7111
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0025 0.001 0.0015
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0036 0.0082 0.0298
Schistosoma mansoni jumonji/arid domain-containing protein 0.0299 0.1786 0.4465
Echinococcus granulosus lysine specific demethylase 5A 0.0299 0.1786 0.4465
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.022 0.0604
Brugia malayi Carboxylesterase family protein 0.0024 0.0003 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0408 0.0436
Trichomonas vaginalis set domain proteins, putative 0.1469 0.9365 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0265 0.0323
Brugia malayi PHD-finger family protein 0.005 0.0171 0.0209
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.0718 0.0875
Echinococcus multilocularis adhesion regulating molecule 1 0.0343 0.2071 0.2071
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0035 0.0075 0.0081
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0227 0.1317 0.4788
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0038 0.0096 0.024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.025 0.0625
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0186 0.1051 0.2627
Brugia malayi glutaminase DH11.1 0.0274 0.1622 0.1975
Brugia malayi jmjC domain containing protein 0.0299 0.1786 0.2175
Schistosoma mansoni cpg binding protein 0.0028 0.0028 0.0069
Brugia malayi chromobox protein homolog 3 0.008 0.0369 0.0449
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0081 0.0372 0.0931
Brugia malayi hypothetical protein 0.0024 0.0006 0.0007
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0148 0.0806 0.2016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0178 0.1003 0.2507
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0054 0.0201 0.0729
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0036 0.0082 0.0278
Schistosoma mansoni hypothetical protein 0.0144 0.0778 0.1944
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0059 0.0232 0.0843
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0048
Echinococcus granulosus subfamily T1A non peptidase ue 0.0258 0.1517 0.3793
Echinococcus multilocularis proteasome subunit beta type 7 0.0641 0.4 0.4
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0186 0.1051 0.2627
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Toxoplasma gondii PCI domain-containing protein 0.0054 0.0199 0.0722
Schistosoma mansoni 26S proteasome subunit S9 0.0065 0.0271 0.0678
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0036
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0141 0.0763 0.1908
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.0003 0.0003
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0276 0.1638 0.5953
Trichomonas vaginalis chromobox protein, putative 0.0143 0.0777 0.083
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0036 0.0082 0.0205
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.002
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0217 0.1253 0.4555
Plasmodium vivax 26S proteasome regulatory subunit RPN10, putative 0.0025 0.001 0.0036
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0048 0.0161 0.0586
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0209 0.1203 0.3007
Onchocerca volvulus 0.0036 0.0082 0.0088
Trypanosoma brucei proteasome beta 6 subunit 0.0276 0.1638 0.5945
Brugia malayi proteasome subunit alpha type 6 0.0259 0.1528 0.1861
Schistosoma mansoni 26S protease regulatory subunit 0.0036 0.0082 0.0205
Brugia malayi jmjC domain containing protein 0.0079 0.0362 0.0441
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0276 0.1638 0.2173
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0258 0.1517 0.1517
Brugia malayi Carboxylesterase family protein 0.0141 0.0763 0.093
Mycobacterium ulcerans glutaminase 0.0274 0.1622 0.4495
Onchocerca volvulus Notchless protein homolog 0.024 0.1404 0.1499
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0238 0.139 0.3474
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0054 0.0201 0.0266
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0019 0.002
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0054 0.0201 0.0244
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.0019 0.5
Echinococcus granulosus chromobox protein 1 0.0143 0.0777 0.1943
Loa Loa (eye worm) glutaminase 0.0274 0.1622 0.1975
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.007 0.0303 0.0758
Toxoplasma gondii 26S proteasome regulatory subunit 0.0035 0.0075 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0085 0.029
Plasmodium vivax proteasome subunit beta type-7, putative 0.0217 0.1253 0.4555
Leishmania major proteasome alpha 7 subunit, putative 0.024 0.1404 0.5091
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0025 0.001 0.0011
Plasmodium vivax 26S protease regulatory subunit 8, putative 0.0035 0.0075 0.0274
Mycobacterium ulcerans NADH dehydrogenase subunit H 0.0144 0.0778 0.2152
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0022 0.0023
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0237 0.1385 0.5022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0041 0.0043
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0047 0.0152 0.0533
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0038 0.0096 0.0103
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0217 0.0231
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0236 0.1379 0.5001
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0052 0.0183 0.0223
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 7 0.0034 0.0067 0.0064
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0174 0.0975 0.2698
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0085 0.0113
Leishmania major proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0003 0.0006
Echinococcus multilocularis chromobox protein 1 0.0143 0.0777 0.0777
Schistosoma mansoni 26S protease regulatory subunit 0.0035 0.0075 0.0189
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0259 0.1528 0.5545
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0059 0.0231 0.0819
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0227 0.1317 0.4777
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Loa Loa (eye worm) jmjC domain-containing protein 0.0299 0.1786 0.2175
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0258 0.1517 0.5514
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0065 0.0271 0.0678
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0053 0.0194 0.0686
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.007 0.0299 0.0365
Leishmania major proteasome regulatory ATPase subunit 0.0035 0.0075 0.0254
Brugia malayi Ets-domain containing protein 0.0075 0.0336 0.0409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0224 0.1298 0.4706
Giardia lamblia PHD finger protein 15 0.0148 0.0806 0.1047
Trichomonas vaginalis 26S proteasome regulatory subunit rpn1, putative 0.0032 0.0058 0.0062
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0019 0.0023
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0236 0.1379 0.1829
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1187 0.7539 0.8049
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0054 0.0201 0.0266
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0448 0.2752 1
Plasmodium vivax proteasome subunit beta type-6, putative 0.0238 0.139 0.5051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.022 0.0604
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0246 0.1443 0.3607
Echinococcus granulosus proteasome subunit alpha type 2 0.0246 0.1443 0.3607
Schistosoma mansoni hypothetical protein 0.0047 0.0153 0.0382
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.024 0.1404 0.3509
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0236 0.1379 0.5011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0041 0.0043
Echinococcus granulosus adhesion regulating molecule 1 0.0343 0.2071 0.5177
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Schistosoma mansoni ets-related 0.0229 0.1329 0.3321
Schistosoma mansoni NADH dehydrogenase subunit 1 0.0039 0.0098 0.0245
Onchocerca volvulus 0.0028 0.0029 0.0031
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.058 0.3605 1
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0065 0.0271 0.033
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097
Brugia malayi 26S protease regulatory subunit 6A 0.0038 0.0096 0.0117
Entamoeba histolytica proteasome regulatory subunit, putative 0.0052 0.0183 0.0242
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0019 0.0069
Echinococcus multilocularis acetylcholinesterase 0.0141 0.0763 0.0763
Loa Loa (eye worm) fli-1 protein 0.0229 0.1329 0.1618
Echinococcus granulosus Chromobox protein 3 0.0023 0.000000050219 0.00000012554
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0909 0.097

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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