Detailed information for compound 1551300

Basic information

Technical information
  • TDR Targets ID: 1551300
  • Name: N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)acetami de
  • MW: 273.714 | Formula: C15H12ClNO2
  • H donors: 2 H acceptors: 2 LogP: 2.24 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1cc2C(O)c3c(c2cc1Cl)cccc3
  • InChi: 1S/C15H12ClNO2/c1-8(18)17-14-7-12-11(6-13(14)16)9-4-2-3-5-10(9)15(12)19/h2-7,15,19H,1H3,(H,17,18)
  • InChiKey: CASGYINMONDDLS-UHFFFAOYSA-N  

Network

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Synonyms

  • N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)ethanamide
  • 6955-66-4
  • NSC67678
  • NCIOpen2_003495
  • Acetamide, N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0042 0.0074 0.0077
Entamoeba histolytica proteasome regulatory subunit, putative 0.0072 0.0517 0.0731
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0578
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0358 0.4791 0.7045
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0238 0.3005 0.4402
Onchocerca volvulus 0.004 0.0038 0.0027
Schistosoma mansoni hypothetical protein 0.006 0.0334 0.0313
Leishmania major proteasome beta 5 subunit, putative 0.0493 0.6801 1
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0285 0.3702 0.5429
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.004 0.0038 0.0038
Loa Loa (eye worm) proteasome subunit alpha type 1 0.026 0.3323 0.3323
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0598
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.004 0.0038 0.0038
Echinococcus granulosus 20S proteasome subunit alpha 6 0.026 0.3323 0.3323
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0238 0.3005 0.4419
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0304 0.398 0.398
Entamoeba histolytica proteasome regulatory subunit, putative 0.0042 0.0072 0.0074
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0418 0.0585
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Brugia malayi proteasome subunit beta type 2 0.0249 0.3167 0.3153
Entamoeba histolytica proteasome regulatory subunit, putative 0.0057 0.0293 0.0401
Loa Loa (eye worm) hypothetical protein 0.004 0.0038 0.0038
Entamoeba histolytica proteasome regulatory subunit, putative 0.006 0.0334 0.0461
Plasmodium vivax proteasome subunit beta type-2, putative 0.0249 0.3167 0.4641
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0065 0.0414 0.0609
Brugia malayi proteasome subunit beta type 3 0.0249 0.3167 0.3153
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0246 0.3118 0.3118
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0072 0.0517 0.076
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0238 0.3005 0.4402
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0246 0.3118 0.3103
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0304 0.398 0.5839
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.006 0.0338 0.0338
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0065 0.0418 0.0614
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0065 0.0414 0.0609
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5387
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Leishmania major proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0283 0.3674 0.5402
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5387
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0039 0.0021 0.0021
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0589
Echinococcus multilocularis proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Toxoplasma gondii PCI domain-containing protein 0.0072 0.0517 0.0497
Schistosoma mansoni multiubiquitin binding protein S5a 0.0042 0.0072 0.0051
Schistosoma mansoni 26S protease regulatory subunit 6b 0.004 0.0038 0.0017
Trypanosoma brucei proteasome beta 6 subunit 0.0304 0.398 0.5852
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0042 0.0074 0.0074
Brugia malayi proteasome subunit alpha type 1 0.026 0.3323 0.3309
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0077 0.0589 0.0837
Brugia malayi Proteasome A-type and B-type family protein 0.0493 0.6801 0.6794
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0229 0.2864 0.4211
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0052 0.0216 0.0216
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0042 0.0072 0.0072
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0065 0.0418 0.0418
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0052 0.0216 0.0317
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.006 0.0334 0.0334
Loa Loa (eye worm) PCI domain-containing protein 0.006 0.0334 0.0334
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.006 0.0334 0.0491
Plasmodium vivax proteasome subunit beta type-1, putative 0.0304 0.398 0.5839
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.006 0.0338 0.0318
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0052 0.0216 0.0216
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.006 0.0338 0.0497
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0077 0.0589 0.0865
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0077 0.0589 0.0837
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0707 1 1
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.006 0.0338 0.0468
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0261 0.3338 0.3338
Loa Loa (eye worm) proteasome subunit beta type 1 0.0304 0.398 0.398
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.006 0.0334 0.0491
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0197 0.2385 0.5
Loa Loa (eye worm) proteasome subunit beta type 3 0.0249 0.3167 0.3167
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.026 0.3323 0.4887
Plasmodium vivax proteasome subunit beta type-6, putative 0.0262 0.3351 0.4911
Schistosoma mansoni hypothetical protein 0.0424 0.5774 0.5764
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0042 0.0073 0.0107
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Loa Loa (eye worm) hypothetical protein 0.0039 0.0021 0.0021
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0493 0.6801 1
Trypanosoma brucei proteasome alpha 7 subunit 0.0264 0.3386 0.4979
Leishmania major proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0042 0.0074 0.0074
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0283 0.3674 0.366
Loa Loa (eye worm) proteasome 26S subunit 0.0039 0.0021 0.0021
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0077 0.0598 0.085
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.006 0.0338 0.0338
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Echinococcus granulosus proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0264 0.3386 0.4963
Giardia lamblia Proteasome subunit beta type 3 0.0249 0.3167 0.4658
Entamoeba histolytica 26S protease regulatory subunit, putative 0.004 0.0038 0.0025
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0197 0.2385 0.3486
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0249 0.3167 0.3167
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0285 0.3702 0.5429
Giardia lamblia Hypothetical protein 0.0072 0.0517 0.076
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0589
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0493 0.6801 1
Plasmodium falciparum proteasome subunit beta type-4 0.0246 0.3118 0.4568
Echinococcus multilocularis proteasome subunit beta type 7 0.0705 0.9963 0.9963
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0493 0.6801 1
Trypanosoma cruzi 20S proteasome subunit 0.0249 0.3167 0.4658
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0283 0.3674 0.366
Giardia lamblia Proteasome subunit beta type 2 0.0249 0.3167 0.4658
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Leishmania major proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0057 0.0293 0.0272
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0358 0.4791 0.478
Giardia lamblia 20S proteasome alpha subunit 5 0.0283 0.3674 0.5402
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.006 0.0334 0.0491
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.026 0.3323 0.4871
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.006 0.0338 0.0338
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0246 0.3118 0.3103
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0493 0.6801 0.6794
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0283 0.3674 0.3674
Leishmania major proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.004 0.0038 0.0056
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0065 0.0414 0.0609
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Brugia malayi Proteasome subunit alpha type 1 0.0228 0.2844 0.2828
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0065 0.0414 0.0394
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0705 0.9963 0.9963
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0039 0.0021 0.0031
Loa Loa (eye worm) PAS-3 protein 0.0229 0.2858 0.2858
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.006 0.0338 0.0468
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0264 0.3386 0.3386
Echinococcus granulosus proteasome prosome macropain 0.0493 0.6801 0.6801
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0077 0.0589 0.0865
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0304 0.398 0.398
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.006 0.0334 0.0334
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0057 0.0293 0.0401
Echinococcus multilocularis proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0261 0.3338 0.4892
Toxoplasma gondii proteasome 26S regulatory subunit 0.0041 0.0055 0.0034
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0249 0.3167 0.3153
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0493 0.6801 1
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0264 0.3386 0.4963
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0238 0.3005 0.4419
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.006 0.0338 0.0497
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0197 0.2385 0.3506
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0598
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0304 0.398 0.5839
Toxoplasma gondii proteasome subunit 0.0262 0.3351 0.3336
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0072 0.0517 0.0731
Toxoplasma gondii PCI domain-containing protein 0.006 0.0334 0.0313
Echinococcus multilocularis adhesion regulating molecule 1 0.0707 1 1
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0283 0.3674 0.5402
Brugia malayi proteasome subunit alpha type 6 0.0285 0.3702 0.3688
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.006 0.0338 0.0318
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0077 0.0598 0.0578
Giardia lamblia 20S proteasome alpha subunit 7 0.0264 0.3386 0.4979
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0052 0.0216 0.0195
Loa Loa (eye worm) hypothetical protein 0.0057 0.0293 0.0293
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0042 0.0074 0.0077
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.006 0.0338 0.0338
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Leishmania major proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Brugia malayi Ubiquitin interaction motif family protein 0.0042 0.0072 0.0051
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0057 0.0293 0.0293
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0017
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.004 0.0038 0.0038
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.006 0.0334 0.0461
Toxoplasma gondii proteasome subunit beta type, putative 0.0493 0.6801 0.6794
Giardia lamblia 20S proteasome alpha subunit 1 0.0285 0.3702 0.5443
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0261 0.3338 0.4892
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0077 0.0598 0.0879
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0065 0.0414 0.0394
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0057 0.0293 0.0431
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0358 0.4791 0.7035
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0249 0.3167 0.4641
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.004 0.0038 0.0056
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0261 0.3338 0.3324
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0065 0.0414 0.0394
Toxoplasma gondii peptidase, T1 family protein 0.0264 0.3386 0.3372
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0271 0.3485 0.3471
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0039 0.0021 0.0031
Entamoeba histolytica proteasome regulatory subunit, putative 0.0077 0.0598 0.085
Leishmania major proteasome alpha 1 subunit, putative 0.026 0.3323 0.4887
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0249 0.3167 0.3153
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0042 0.0072 0.0106
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0249 0.3167 0.4641
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.004 0.0038 0.0038
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0021 0.0031
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0283 0.3674 0.5387
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0261 0.3338 0.4892
Schistosoma mansoni hypothetical protein 0.0173 0.2023 0.2006
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0065 0.0418 0.0397
Brugia malayi proteasome subunit beta type 1 0.0304 0.398 0.3967
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0042 0.0072 0.0106
Brugia malayi Proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0098
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0285 0.3702 0.5429
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0493 0.6801 1
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0065 0.0414 0.058
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0707 1 1
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Brugia malayi Proteasome A-type and B-type family protein 0.0246 0.3118 0.3103
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0065 0.0414 0.058
Plasmodium vivax proteasome subunit alpha type-1, putative 0.026 0.3323 0.4871
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.006 0.0338 0.0497
Echinococcus granulosus 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0293 0.0293
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0368 0.4943 0.7259
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0246 0.3118 0.3118
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0057 0.0293 0.0293
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Plasmodium vivax proteasome subunit beta type-4, putative 0.0246 0.3118 0.4568
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.006 0.0338 0.0468
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.006 0.0338 0.0318
Loa Loa (eye worm) proteasome subunit beta type 2 0.0249 0.3167 0.3167
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0065 0.0418 0.0614
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0261 0.3338 0.3338
Giardia lamblia 20S proteasome alpha subunit 3 0.0261 0.3338 0.4908
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.004 0.0038 0.0056
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Loa Loa (eye worm) proteasome Regulatory Particle 0.0065 0.0414 0.0414
Toxoplasma gondii hypothetical protein 0.0052 0.0228 0.0207
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0493 0.6801 1
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0262 0.3351 0.4927
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0119
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0249 0.3167 0.3167
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0262 0.3351 0.4927
Echinococcus multilocularis proteasome subunit beta type 6 0.0262 0.3351 0.3351
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0304 0.398 0.3967
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.004 0.0038 0.0056
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.004 0.0038 0.0025
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0039 0.0021 0.0031
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.3005 0.4419
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0424 0.5774 0.5764
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0246 0.3118 0.3118
Leishmania major proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Leishmania major proteasome beta 7 subunit, putative 0.0246 0.3118 0.4585
Giardia lamblia 20S proteasome alpha subunit 2 0.0271 0.3485 0.5124
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0264 0.3386 0.3386
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0264 0.3386 0.3372
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.026 0.3323 0.3309
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.004 0.0038 0.0056
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0077 0.0589 0.0865
Loa Loa (eye worm) RPN-3 protein 0.0077 0.0598 0.0598
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.011 0.1089 0.1575
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0025
Echinococcus granulosus proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0042 0.0074 0.0077
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0052 0.0216 0.0195
Brugia malayi Proteasome A-type and B-type family protein 0.0262 0.3351 0.3336
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0041 0.0055 0.0082
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0493 0.6801 1
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.006 0.0338 0.0468
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.026 0.3323 0.3309
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0238 0.3005 0.4419
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0246 0.3118 0.4585
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0072 0.0517 0.0517
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0249 0.3167 0.3153
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.004 0.0038 0.0056
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0264 0.3386 0.4979
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Entamoeba histolytica hypothetical protein 0.0052 0.0216 0.0287
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0578
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0264 0.3386 0.4963
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0493 0.6801 1
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0057 0.0293 0.0431
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0271 0.3485 0.5109
Schistosoma mansoni 26S proteasome subunit S9 0.0072 0.0517 0.0497
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0304 0.398 0.3967
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0197 0.2385 0.2368
Echinococcus multilocularis proteasome (prosome, macropain) 0.0493 0.6801 0.6801
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0039 0.0021 0.0031
Schistosoma mansoni 26S protease regulatory subunit 0.004 0.0038 0.0017
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.004 0.0038 0.0056
Entamoeba histolytica 26S protease regulatory subunit, putative 0.004 0.0038 0.0025
Toxoplasma gondii proteasome regulatory subunit 0.006 0.0338 0.0318
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0042 0.0074 0.0108
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0197 0.2385 0.3486
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0246 0.3118 0.4585
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0249 0.3167 0.3153
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0249 0.3167 0.4658
Giardia lamblia 26S protease regulatory subunit 7 0.0039 0.0021 0.0031
Plasmodium falciparum proteasome subunit beta type-5 0.0493 0.6801 1
Brugia malayi Probable 26S protease regulatory subunit 4 0.004 0.0038 0.0017
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.006 0.0338 0.0338
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0065 0.0418 0.0614
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0072 0.0517 0.076
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Giardia lamblia Proteasome subunit beta type 1 0.0304 0.398 0.5852
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.3005 0.3005
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.004 0.0038 0.0056
Giardia lamblia 26S protease regulatory subunit 6B 0.004 0.0038 0.0056
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0065 0.0414 0.0609
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.006 0.0334 0.0491
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0493 0.6801 0.6801
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0065 0.0414 0.0414
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0045 0.0119 0.0176
Leishmania major proteasome regulatory ATPase subunit 0.0039 0.0021 0.0031
Echinococcus granulosus adhesion regulating molecule 1 0.0707 1 1
Mycobacterium ulcerans proteasome PrcB 0.0493 0.6801 1
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0283 0.3674 0.3674
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0065 0.0418 0.0614
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.026 0.3323 0.4887
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0065 0.0414 0.0609
Leishmania major proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Leishmania major hypothetical protein, conserved 0.0368 0.4943 0.7268
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0057 0.0293 0.0401
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0271 0.3485 0.3471
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.006 0.0338 0.0318
Loa Loa (eye worm) proteasome regulatory particle 0.0072 0.0517 0.0517
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0065 0.0414 0.0414
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0261 0.3338 0.4908
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0039 0.0021 0.0021
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Toxoplasma gondii proteasome subunit alpha type, putative 0.0161 0.1851 0.1834
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0065 0.0418 0.0585
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0072 0.0517 0.076
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0057 0.0293 0.0431
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.026 0.3323 0.4871
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0249 0.3167 0.4658
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0197 0.2385 0.3506
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.006 0.0338 0.0468
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Leishmania major proteasome beta 2 subunit, putative 0.0249 0.3167 0.4658
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0249 0.3167 0.4641
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0304 0.398 0.5852
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0072 0.0517 0.0497
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0246 0.3118 0.4568
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0042 0.0072 0.0106
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0072 0.0517 0.0731
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0173 0.2023 0.2023
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0042 0.0074 0.0108
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0077 0.0589 0.0568
Loa Loa (eye worm) hypothetical protein 0.0707 1 1
Loa Loa (eye worm) RPT-2 protein 0.004 0.0038 0.0038
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0262 0.3351 0.3351
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.004 0.0038 0.0056
Echinococcus granulosus Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0238 0.3005 0.299
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.004 0.0038 0.0017
Brugia malayi 20S proteasome alpha5 subunit 0.0283 0.3674 0.366
Echinococcus granulosus proteasome subunit beta type 6 0.0262 0.3351 0.3351
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0057 0.0293 0.0272
Echinococcus granulosus proteasome subunit beta t family 0.0249 0.3167 0.3167
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0077 0.0589 0.0589
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0358 0.4791 0.4791
Trichomonas vaginalis 26S proteasome subunit, putative 0.006 0.0334 0.0491
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0271 0.3485 0.5109
Brugia malayi proteasome subunit alpha type 2 0.0271 0.3485 0.3471
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0262 0.3351 0.3336
Loa Loa (eye worm) hypothetical protein 0.0424 0.5774 0.5774
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0197 0.2385 0.3506
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0246 0.3118 0.4585
Giardia lamblia 20S proteasome alpha subunit 6 0.026 0.3323 0.4887
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0041 0.0055 0.005
Toxoplasma gondii proteasome subunit alpha1, putative 0.0285 0.3702 0.3688
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0249 0.3167 0.3167
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.004 0.0038 0.0025
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0052 0.0216 0.0287
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0058 0.0308 0.0453
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0025
Brugia malayi 26S protease regulatory subunit 6A 0.0042 0.0074 0.0052
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0262 0.3351 0.4911
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0264 0.3386 0.4963
Brugia malayi proteasome subunit alpha type 4 0.0229 0.2858 0.2843
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0072 0.0517 0.076
Giardia lamblia 26S protease regulatory subunit 8 0.0039 0.0021 0.0031
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0414 0.058
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0042 0.0072 0.0072
Toxoplasma gondii proteasome beta subunit 0.0249 0.3167 0.3153
Loa Loa (eye worm) hypothetical protein 0.004 0.0038 0.0038
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0358 0.4791 0.7035
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0283 0.3674 0.366
Echinococcus granulosus subfamily T1A non peptidase ue 0.0283 0.3674 0.3674
Brugia malayi 26S proteasome subunit P45 family protein 0.004 0.0038 0.0017
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0283 0.3674 0.5387
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0077 0.0589 0.0865
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0358 0.4791 0.7035
Plasmodium vivax proteasome subunit beta type-5, putative 0.0493 0.6801 1
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.006 0.0334 0.0461
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.026 0.3323 0.3323
Brugia malayi PCI domain containing protein 0.0065 0.0418 0.0397
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Loa Loa (eye worm) PCI domain-containing protein 0.0065 0.0418 0.0418
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0077 0.0589 0.0865
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0072 0.0517 0.0517
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0261 0.3338 0.4892
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0173 0.2023 0.2023
Plasmodium vivax proteasome subunit beta type-7, putative 0.0238 0.3005 0.4402
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0065 0.0418 0.0418
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0052 0.0216 0.0287
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0039 0.0021 0.0031
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Echinococcus granulosus Proteasome subunit alpha beta 0.0264 0.3386 0.3386
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.006 0.0338 0.0338
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0057 0.0293 0.0272
Brugia malayi PCI domain containing protein 0.006 0.0334 0.0313
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0271 0.3485 0.5109
Giardia lamblia 20S proteasome alpha subunit 4 0.0358 0.4791 0.7045
Toxoplasma gondii heat shock protein hslv, putative 0.0197 0.2385 0.2368
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0262 0.3351 0.4911
Toxoplasma gondii SAC3/GANP family protein 0.0057 0.0293 0.0272
Toxoplasma gondii proteasome subunit alpha type, putative 0.0261 0.3338 0.3324
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0285 0.3702 0.5443
Plasmodium vivax proteasome subunit beta type-3, putative 0.0249 0.3167 0.4641
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0042 0.0072 0.0051
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Onchocerca volvulus Notchless protein homolog 0.0264 0.3386 0.5493
Loa Loa (eye worm) hypothetical protein 0.0052 0.0228 0.0228
Onchocerca volvulus 0.004 0.0038 0.0027
Brugia malayi proteasome subunit alpha type 3 0.0264 0.3386 0.3372
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0077 0.0598 0.0879
Toxoplasma gondii PCI domain-containing protein 0.0077 0.0598 0.0578
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Giardia lamblia 26S protease regulatory subunit 6A 0.0042 0.0074 0.0108
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0039 0.0021 0.0031
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.026 0.3323 0.4887
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Echinococcus granulosus proteasome subunit beta type 7 0.0705 0.9963 0.9963
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0065 0.0418 0.0585
Brugia malayi Proteasome subunit alpha type 7-1 0.0358 0.4791 0.478
Schistosoma mansoni proteasome regulatory subunit-related 0.0065 0.0418 0.0397
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0449 0.6146 1
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Brugia malayi Proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0098
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.006 0.0338 0.0468
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0042 0.0074 0.0052
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0285 0.3702 0.3688
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0358 0.4791 0.7035
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0251 0.3194 0.318
Leishmania major proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0249 0.3167 0.4641
Brugia malayi Proteasome A-type and B-type family protein 0.0705 0.9963 0.9963
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0039 0.0021 0.0031
Brugia malayi 26S proteasome regulatory subunit rpn11 0.006 0.0338 0.0318
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0197 0.2385 0.3506
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0042 0.0074 0.0074
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0077 0.0598 0.0879
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0249 0.3167 0.3153
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0197 0.2385 0.3486
Trypanosoma brucei proteasome beta 7 subunit 0.0246 0.3118 0.4585

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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