Detailed information for compound 1551300

Basic information

Technical information
  • TDR Targets ID: 1551300
  • Name: N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)acetami de
  • MW: 273.714 | Formula: C15H12ClNO2
  • H donors: 2 H acceptors: 2 LogP: 2.24 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1cc2C(O)c3c(c2cc1Cl)cccc3
  • InChi: 1S/C15H12ClNO2/c1-8(18)17-14-7-12-11(6-13(14)16)9-4-2-3-5-10(9)15(12)19/h2-7,15,19H,1H3,(H,17,18)
  • InChiKey: CASGYINMONDDLS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)ethanamide
  • 6955-66-4
  • NSC67678
  • NCIOpen2_003495
  • Acetamide, N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.004 0.0038 0.0056
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.006 0.0338 0.0468
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0283 0.3674 0.3674
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0042 0.0074 0.0074
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0493 0.6801 1
Giardia lamblia 20S proteasome alpha subunit 1 0.0285 0.3702 0.5443
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Schistosoma mansoni hypothetical protein 0.0424 0.5774 0.5764
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0052 0.0216 0.0195
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0249 0.3167 0.3167
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.004 0.0038 0.0038
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.026 0.3323 0.4887
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.006 0.0334 0.0334
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0017
Toxoplasma gondii proteasome beta subunit 0.0249 0.3167 0.3153
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0052 0.0216 0.0287
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0283 0.3674 0.366
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Giardia lamblia 20S proteasome alpha subunit 7 0.0264 0.3386 0.4979
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0042 0.0074 0.0077
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0077 0.0589 0.0865
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0057 0.0293 0.0272
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0262 0.3351 0.4927
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0493 0.6801 1
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0707 1 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.3005 0.4419
Echinococcus multilocularis adhesion regulating molecule 1 0.0707 1 1
Giardia lamblia 26S protease regulatory subunit 6B 0.004 0.0038 0.0056
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0077 0.0598 0.0879
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0262 0.3351 0.3351
Leishmania major proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Loa Loa (eye worm) hypothetical protein 0.0057 0.0293 0.0293
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0304 0.398 0.5839
Brugia malayi Proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0098
Entamoeba histolytica proteasome regulatory subunit, putative 0.0077 0.0598 0.085
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.006 0.0338 0.0338
Giardia lamblia 20S proteasome alpha subunit 3 0.0261 0.3338 0.4908
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0246 0.3118 0.3118
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0424 0.5774 0.5764
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0238 0.3005 0.4419
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0065 0.0418 0.0614
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0065 0.0418 0.0397
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0251 0.3194 0.318
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0358 0.4791 0.7035
Schistosoma mansoni multiubiquitin binding protein S5a 0.0042 0.0072 0.0051
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0271 0.3485 0.5109
Toxoplasma gondii SAC3/GANP family protein 0.0057 0.0293 0.0272
Onchocerca volvulus 0.004 0.0038 0.0027
Onchocerca volvulus Notchless protein homolog 0.0264 0.3386 0.5493
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0249 0.3167 0.4658
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5387
Brugia malayi proteasome subunit alpha type 4 0.0229 0.2858 0.2843
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0358 0.4791 0.7035
Brugia malayi Proteasome subunit alpha type 7-1 0.0358 0.4791 0.478
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0271 0.3485 0.5109
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0065 0.0414 0.0394
Entamoeba histolytica proteasome regulatory subunit, putative 0.006 0.0334 0.0461
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.006 0.0334 0.0491
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0197 0.2385 0.2368
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0077 0.0598 0.0578
Plasmodium vivax proteasome subunit beta type-1, putative 0.0304 0.398 0.5839
Loa Loa (eye worm) hypothetical protein 0.0424 0.5774 0.5774
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0249 0.3167 0.3153
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Loa Loa (eye worm) hypothetical protein 0.0039 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.0038 0.0038
Echinococcus granulosus proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Toxoplasma gondii hypothetical protein 0.0052 0.0228 0.0207
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0065 0.0414 0.0394
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0077 0.0598 0.085
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0264 0.3386 0.4963
Plasmodium vivax proteasome subunit beta type-7, putative 0.0238 0.3005 0.4402
Toxoplasma gondii PCI domain-containing protein 0.006 0.0334 0.0313
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0264 0.3386 0.3386
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.006 0.0334 0.0334
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0238 0.3005 0.299
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0246 0.3118 0.3118
Loa Loa (eye worm) proteasome subunit beta type 3 0.0249 0.3167 0.3167
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0285 0.3702 0.5429
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0065 0.0418 0.0614
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0065 0.0418 0.0418
Schistosoma mansoni 26S protease regulatory subunit 6b 0.004 0.0038 0.0017
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0197 0.2385 0.3486
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0072 0.0517 0.0497
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0042 0.0073 0.0107
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0025
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Brugia malayi proteasome subunit alpha type 3 0.0264 0.3386 0.3372
Entamoeba histolytica proteasome regulatory subunit, putative 0.0072 0.0517 0.0731
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Brugia malayi Proteasome A-type and B-type family protein 0.0262 0.3351 0.3336
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0065 0.0418 0.0614
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.004 0.0038 0.0056
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0039 0.0021 0.0031
Brugia malayi Proteasome A-type and B-type family protein 0.0493 0.6801 0.6794
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0304 0.398 0.3967
Brugia malayi Probable 26S protease regulatory subunit 4 0.004 0.0038 0.0017
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0358 0.4791 0.4791
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0285 0.3702 0.5429
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0077 0.0589 0.0865
Loa Loa (eye worm) proteasome subunit beta type 2 0.0249 0.3167 0.3167
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0042 0.0072 0.0072
Leishmania major proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.006 0.0338 0.0318
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.006 0.0338 0.0338
Entamoeba histolytica proteasome regulatory subunit, putative 0.0057 0.0293 0.0401
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0039 0.0021 0.0031
Giardia lamblia Proteasome subunit beta type 3 0.0249 0.3167 0.4658
Trypanosoma brucei proteasome beta 6 subunit 0.0304 0.398 0.5852
Plasmodium falciparum proteasome subunit beta type-5 0.0493 0.6801 1
Plasmodium vivax proteasome subunit beta type-2, putative 0.0249 0.3167 0.4641
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0197 0.2385 0.3506
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0197 0.2385 0.3486
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.004 0.0038 0.0025
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0065 0.0414 0.0609
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0705 0.9963 0.9963
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0493 0.6801 1
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0249 0.3167 0.4641
Brugia malayi Proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0098
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0072 0.0517 0.076
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.006 0.0338 0.0338
Onchocerca volvulus 0.004 0.0038 0.0027
Giardia lamblia Proteasome subunit beta type 1 0.0304 0.398 0.5852
Brugia malayi proteasome subunit alpha type 1 0.026 0.3323 0.3309
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0358 0.4791 0.7045
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.004 0.0038 0.0038
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0077 0.0589 0.0865
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0077 0.0598 0.0879
Leishmania major proteasome beta 7 subunit, putative 0.0246 0.3118 0.4585
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0039 0.0021 0.0031
Loa Loa (eye worm) proteasome Regulatory Particle 0.0065 0.0414 0.0414
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0072 0.0517 0.076
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0238 0.3005 0.4402
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0025
Echinococcus granulosus Proteasome subunit alpha beta 0.0264 0.3386 0.3386
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0264 0.3386 0.3386
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0042 0.0074 0.0077
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.026 0.3323 0.3309
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Schistosoma mansoni hypothetical protein 0.006 0.0334 0.0313
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.006 0.0338 0.0318
Giardia lamblia 20S proteasome alpha subunit 2 0.0271 0.3485 0.5124
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.006 0.0338 0.0318
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.004 0.0038 0.0056
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0285 0.3702 0.3688
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0249 0.3167 0.3153
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Brugia malayi Ubiquitin interaction motif family protein 0.0042 0.0072 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0038 0.0038
Giardia lamblia 26S protease regulatory subunit 6A 0.0042 0.0074 0.0108
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0304 0.398 0.5852
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0077 0.0598 0.0879
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Toxoplasma gondii proteasome subunit 0.0262 0.3351 0.3336
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0052 0.0216 0.0287
Plasmodium falciparum proteasome subunit beta type-4 0.0246 0.3118 0.4568
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0578
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0493 0.6801 1
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.006 0.0334 0.0491
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0283 0.3674 0.366
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0039 0.0021 0.0031
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0057 0.0293 0.0293
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0197 0.2385 0.5
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0077 0.0589 0.0865
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.026 0.3323 0.4871
Entamoeba histolytica proteasome regulatory subunit, putative 0.0042 0.0072 0.0074
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.006 0.0338 0.0468
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Plasmodium vivax proteasome subunit beta type-3, putative 0.0249 0.3167 0.4641
Brugia malayi PCI domain containing protein 0.0065 0.0418 0.0397
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0414 0.058
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0283 0.3674 0.5402
Plasmodium vivax proteasome subunit beta type-5, putative 0.0493 0.6801 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.3005 0.3005
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0418 0.0585
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Giardia lamblia Hypothetical protein 0.0072 0.0517 0.076
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0039 0.0021 0.0031
Echinococcus granulosus proteasome subunit beta type 7 0.0705 0.9963 0.9963
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0271 0.3485 0.3471
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0065 0.0414 0.0414
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Entamoeba histolytica hypothetical protein 0.0052 0.0216 0.0287
Echinococcus granulosus proteasome subunit beta type 6 0.0262 0.3351 0.3351
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0042 0.0072 0.0106
Echinococcus multilocularis proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0042 0.0074 0.0108
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0304 0.398 0.5839
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0039 0.0021 0.0031
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0246 0.3118 0.3103
Brugia malayi PCI domain containing protein 0.006 0.0334 0.0313
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0077 0.0589 0.0568
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0197 0.2385 0.3506
Schistosoma mansoni 26S proteasome subunit S9 0.0072 0.0517 0.0497
Echinococcus granulosus subfamily T1A non peptidase ue 0.0283 0.3674 0.3674
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.006 0.0334 0.0491
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.006 0.0338 0.0338
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.004 0.0038 0.0056
Schistosoma mansoni proteasome regulatory subunit-related 0.0065 0.0418 0.0397
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0249 0.3167 0.3167
Loa Loa (eye worm) RPN-3 protein 0.0077 0.0598 0.0598
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0057 0.0293 0.0272
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.006 0.0338 0.0468
Loa Loa (eye worm) proteasome 26S subunit 0.0039 0.0021 0.0021
Echinococcus granulosus proteasome prosome macropain 0.0493 0.6801 0.6801
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0285 0.3702 0.5443
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0271 0.3485 0.3471
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0229 0.2864 0.4211
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0271 0.3485 0.5109
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0246 0.3118 0.3118
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0197 0.2385 0.3506
Toxoplasma gondii PCI domain-containing protein 0.0072 0.0517 0.0497
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0358 0.4791 0.7035
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Toxoplasma gondii heat shock protein hslv, putative 0.0197 0.2385 0.2368
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0072 0.0517 0.0731
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0057 0.0293 0.0431
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0261 0.3338 0.4892
Leishmania major proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0065 0.0414 0.0609
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0261 0.3338 0.3338
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0249 0.3167 0.3153
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0368 0.4943 0.7259
Trypanosoma cruzi 20S proteasome subunit 0.0249 0.3167 0.4658
Plasmodium vivax proteasome subunit beta type-6, putative 0.0262 0.3351 0.4911
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0042 0.0074 0.0074
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0042 0.0074 0.0108
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0042 0.0074 0.0052
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0077 0.0589 0.0837
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0039 0.0021 0.0021
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0304 0.398 0.3967
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0072 0.0517 0.0517
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0589
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0261 0.3338 0.3324
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0238 0.3005 0.4419
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.006 0.0338 0.0338
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0057 0.0293 0.0293
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0042 0.0074 0.0074
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.004 0.0038 0.0056
Loa Loa (eye worm) proteasome regulatory particle 0.0072 0.0517 0.0517
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Loa Loa (eye worm) PAS-3 protein 0.0229 0.2858 0.2858
Echinococcus granulosus 20S proteasome subunit alpha 6 0.026 0.3323 0.3323
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0052 0.0216 0.0195
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0493 0.6801 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0293 0.0293
Giardia lamblia 20S proteasome alpha subunit 6 0.026 0.3323 0.4887
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0264 0.3386 0.3372
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0261 0.3338 0.4908
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0493 0.6801 0.6794
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0065 0.0414 0.0394
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Loa Loa (eye worm) PCI domain-containing protein 0.006 0.0334 0.0334
Leishmania major hypothetical protein, conserved 0.0368 0.4943 0.7268
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0283 0.3674 0.3674
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0065 0.0414 0.0609
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.006 0.0334 0.0461
Leishmania major proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0493 0.6801 1
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0261 0.3338 0.4892
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0304 0.398 0.398
Loa Loa (eye worm) RPT-2 protein 0.004 0.0038 0.0038
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.004 0.0038 0.0025
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.006 0.0338 0.0468
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0042 0.0072 0.0051
Toxoplasma gondii proteasome regulatory subunit 0.006 0.0338 0.0318
Giardia lamblia 20S proteasome alpha subunit 5 0.0283 0.3674 0.5402
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Echinococcus multilocularis proteasome subunit beta type 6 0.0262 0.3351 0.3351
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0249 0.3167 0.3153
Loa Loa (eye worm) hypothetical protein 0.0052 0.0228 0.0228
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.026 0.3323 0.3309
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0707 1 1
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0039 0.0021 0.0031
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0065 0.0414 0.0414
Brugia malayi proteasome subunit beta type 2 0.0249 0.3167 0.3153
Brugia malayi proteasome subunit beta type 3 0.0249 0.3167 0.3153
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0052 0.0216 0.0216
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0021 0.0031
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Brugia malayi proteasome subunit alpha type 2 0.0271 0.3485 0.3471
Loa Loa (eye worm) proteasome subunit beta type 1 0.0304 0.398 0.398
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0077 0.0589 0.0837
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0057 0.0293 0.0431
Giardia lamblia 20S proteasome alpha subunit 4 0.0358 0.4791 0.7045
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.004 0.0038 0.0056
Brugia malayi Proteasome A-type and B-type family protein 0.0705 0.9963 0.9963
Toxoplasma gondii proteasome 26S regulatory subunit 0.0041 0.0055 0.0034
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0065 0.0418 0.0418
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Leishmania major proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.006 0.0338 0.0318
Brugia malayi 26S proteasome subunit P45 family protein 0.004 0.0038 0.0017
Toxoplasma gondii PCI domain-containing protein 0.0077 0.0598 0.0578
Loa Loa (eye worm) proteasome subunit alpha type 1 0.026 0.3323 0.3323
Toxoplasma gondii proteasome subunit alpha type, putative 0.0161 0.1851 0.1834
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0042 0.0072 0.0106
Toxoplasma gondii peptidase, T1 family protein 0.0264 0.3386 0.3372
Toxoplasma gondii proteasome subunit alpha type, putative 0.0261 0.3338 0.3324
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0072 0.0517 0.0731
Echinococcus multilocularis proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Schistosoma mansoni 26S protease regulatory subunit 0.004 0.0038 0.0017
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0057 0.0293 0.0401
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0065 0.0414 0.0609
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0246 0.3118 0.4585
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0249 0.3167 0.4658
Entamoeba histolytica 26S protease regulatory subunit, putative 0.004 0.0038 0.0025
Echinococcus granulosus 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.011 0.1089 0.1575
Giardia lamblia 26S protease regulatory subunit 7 0.0039 0.0021 0.0031
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0283 0.3674 0.366
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0493 0.6801 1
Toxoplasma gondii proteasome subunit alpha1, putative 0.0285 0.3702 0.3688
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0283 0.3674 0.5402
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0072 0.0517 0.076
Trypanosoma brucei proteasome beta 7 subunit 0.0246 0.3118 0.4585
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0358 0.4791 0.478
Loa Loa (eye worm) PCI domain-containing protein 0.0065 0.0418 0.0418
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0058 0.0308 0.0453
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0246 0.3118 0.4585
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0262 0.3351 0.4927
Brugia malayi 26S proteasome regulatory subunit rpn11 0.006 0.0338 0.0318
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.026 0.3323 0.4871
Brugia malayi Proteasome subunit alpha type 1 0.0228 0.2844 0.2828
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0249 0.3167 0.4641
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0238 0.3005 0.4402
Leishmania major proteasome beta 2 subunit, putative 0.0249 0.3167 0.4658
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0042 0.0072 0.0106
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Loa Loa (eye worm) hypothetical protein 0.0707 1 1
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5387
Leishmania major proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0197 0.2385 0.3486
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.004 0.0038 0.0038
Toxoplasma gondii proteasome subunit beta type, putative 0.0493 0.6801 0.6794
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0246 0.3118 0.4568
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0264 0.3386 0.4963
Trypanosoma brucei proteasome alpha 7 subunit 0.0264 0.3386 0.4979
Echinococcus multilocularis proteasome (prosome, macropain) 0.0493 0.6801 0.6801
Echinococcus granulosus proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.006 0.0334 0.0461
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0283 0.3674 0.5387
Leishmania major proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0264 0.3386 0.4979
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.006 0.0338 0.0497
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0119
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0598
Giardia lamblia Proteasome subunit beta type 2 0.0249 0.3167 0.4658
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Brugia malayi 20S proteasome alpha5 subunit 0.0283 0.3674 0.366
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0493 0.6801 1
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0264 0.3386 0.4963
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0589
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0264 0.3386 0.4963
Echinococcus granulosus proteasome subunit beta t family 0.0249 0.3167 0.3167
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0283 0.3674 0.5387
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0261 0.3338 0.4892
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0045 0.0119 0.0176
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0065 0.0414 0.0609
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.006 0.0334 0.0491
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0249 0.3167 0.4641
Leishmania major proteasome alpha 1 subunit, putative 0.026 0.3323 0.4887
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.006 0.0338 0.0338
Brugia malayi Proteasome A-type and B-type family protein 0.0246 0.3118 0.3103
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0261 0.3338 0.3338
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0262 0.3351 0.3336
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.026 0.3323 0.4887
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0042 0.0072 0.0072
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0072 0.0517 0.0517
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.026 0.3323 0.4887
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0249 0.3167 0.3167
Leishmania major proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0065 0.0418 0.0614
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.004 0.0038 0.0038
Brugia malayi proteasome subunit beta type 1 0.0304 0.398 0.3967
Mycobacterium ulcerans proteasome PrcB 0.0493 0.6801 1
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0077 0.0589 0.0589
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0598
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0065 0.0418 0.0585
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0261 0.3338 0.4892
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0493 0.6801 0.6801
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0449 0.6146 1
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0039 0.0021 0.0021
Trichomonas vaginalis 26S proteasome subunit, putative 0.006 0.0334 0.0491
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.004 0.0038 0.0017
Schistosoma mansoni hypothetical protein 0.0173 0.2023 0.2006
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0238 0.3005 0.4419
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0057 0.0293 0.0431
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0304 0.398 0.398
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0358 0.4791 0.7035
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0578
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0262 0.3351 0.4911
Leishmania major proteasome regulatory ATPase subunit 0.0039 0.0021 0.0031
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0246 0.3118 0.4585
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0052 0.0216 0.0216
Plasmodium vivax proteasome subunit alpha type-1, putative 0.026 0.3323 0.4871
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0041 0.0055 0.005
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0246 0.3118 0.3103
Echinococcus granulosus Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Giardia lamblia 26S protease regulatory subunit 8 0.0039 0.0021 0.0031
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0057 0.0293 0.0272
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0249 0.3167 0.3153
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0262 0.3351 0.4911
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.006 0.0338 0.0468
Plasmodium vivax proteasome subunit beta type-4, putative 0.0246 0.3118 0.4568
Brugia malayi proteasome subunit alpha type 6 0.0285 0.3702 0.3688
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0173 0.2023 0.2023
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0052 0.0216 0.0317
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0065 0.0414 0.058
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Brugia malayi 26S protease regulatory subunit 6A 0.0042 0.0074 0.0052
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.006 0.0338 0.0497
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0197 0.2385 0.3506
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0249 0.3167 0.4641
Echinococcus multilocularis proteasome subunit beta type 7 0.0705 0.9963 0.9963
Leishmania major proteasome beta 5 subunit, putative 0.0493 0.6801 1
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.004 0.0038 0.0056
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0057 0.0293 0.0401
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0173 0.2023 0.2023
Echinococcus granulosus adhesion regulating molecule 1 0.0707 1 1
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0077 0.0589 0.0865
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0072 0.0517 0.076
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0065 0.0414 0.058
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0042 0.0074 0.0077
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.026 0.3323 0.3323
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.006 0.0338 0.0468
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.004 0.0038 0.0056
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.006 0.0338 0.0497
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0065 0.0418 0.0585
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0285 0.3702 0.5429
Entamoeba histolytica 26S protease regulatory subunit, putative 0.004 0.0038 0.0025
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0041 0.0055 0.0082
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.004 0.0038 0.0056

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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