Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | slit 2 protein | 0.0098 | 0.0986 | 0.0986 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | septate junction protein | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Schistosoma mansoni | cell polarity protein | 0.0098 | 0.0986 | 0.0986 |
Echinococcus multilocularis | protein jagged 1 | 0.0098 | 0.0986 | 0.0986 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0098 | 0.0986 | 0.0986 |
Onchocerca volvulus | Dual oxidase homolog | 0.0433 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Onchocerca volvulus | 0.0433 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Echinococcus granulosus | fibropellin Ia | 0.0098 | 0.0986 | 0.0986 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | notch | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0433 | 1 | 1 |
Echinococcus multilocularis | neural cadherin | 0.0098 | 0.0986 | 0.0986 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0098 | 0.0986 | 0.0986 |
Brugia malayi | Animal haem peroxidase family protein | 0.0433 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0433 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0986 | 0.0986 |
Echinococcus multilocularis | protein jagged 2 | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | slit | 0.0098 | 0.0986 | 0.0986 |
Onchocerca volvulus | 0.0433 | 1 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0986 | 0.0986 |
Brugia malayi | Animal haem peroxidase family protein | 0.0433 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | notch | 0.0098 | 0.0986 | 0.0986 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0433 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0098 | 0.0986 | 0.0986 |
Echinococcus granulosus | peroxidasin | 0.0433 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0098 | 0.0986 | 0.0986 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0 | 0.5 |
Brugia malayi | Peroxidasin | 0.0433 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | notch | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | notch | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0433 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0098 | 0.0986 | 0.0986 |
Echinococcus multilocularis | fibropellin Ia | 0.0098 | 0.0986 | 0.0986 |
Echinococcus multilocularis | protein jagged 1 | 0.0098 | 0.0986 | 0.0986 |
Onchocerca volvulus | Peroxidase homolog | 0.0433 | 1 | 1 |
Echinococcus granulosus | notch | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | peroxidasin | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0433 | 1 | 1 |
Giardia lamblia | High cysteine protein | 0.0098 | 0.0986 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0433 | 1 | 1 |
Echinococcus granulosus | delta-like protein 1 | 0.0098 | 0.0986 | 0.0986 |
Brugia malayi | Blistered cuticle protein 3 | 0.0433 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0 | 0.5 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0986 | 0.0986 |
Schistosoma mansoni | notch | 0.0098 | 0.0986 | 0.0986 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0 | 0.5 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0098 | 0.0986 | 0.0986 |
Echinococcus granulosus | protein jagged 2 | 0.0098 | 0.0986 | 0.0986 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0098 | 0.0986 | 1 |
Schistosoma mansoni | notch | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0433 | 1 | 1 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0098 | 0.0986 | 0.0986 |
Onchocerca volvulus | Peroxidasin homolog | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0433 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0433 | 1 | 1 |
Echinococcus multilocularis | notch | 0.0098 | 0.0986 | 0.0986 |
Onchocerca volvulus | 0.0433 | 1 | 1 | |
Echinococcus granulosus | slit 2 protein | 0.0098 | 0.0986 | 0.0986 |
Echinococcus granulosus | neural cadherin | 0.0098 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0433 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0986 | 0.0986 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0 | 0.5 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0098 | 0.0986 | 0.0986 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 31.6228 uM | PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.