Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Glycosyltransferase protein LARGE1 | 0.0059 | 0.0085 | 0.0262 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 0.0629 |
Schistosoma mansoni | Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial | 0.0045 | 0.0016 | 0.0026 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0084 | 0.0204 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0078 | 0.0178 | 0.0301 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0587 | 0.2623 | 0.8098 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0078 | 0.0178 | 0.0549 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0587 | 0.2623 | 0.2623 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0078 | 0.0178 | 0.0301 |
Schistosoma mansoni | tar DNA-binding protein | 0.059 | 0.264 | 0.4476 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0065 | 0.0112 | 0.0112 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.2121 | 1 | 1 |
Brugia malayi | Probable ClpP-like protease | 0.0084 | 0.0204 | 0.0204 |
Schistosoma mansoni | glycosyltransferase-related | 0.008 | 0.0183 | 0.0311 |
Brugia malayi | RNA recognition motif domain containing protein | 0.059 | 0.264 | 0.264 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.0045 | 0.0016 | 0.0016 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0587 | 0.2623 | 0.8098 |
Brugia malayi | Probable isocitrate dehydrogenase | 0.0045 | 0.0016 | 0.0016 |
Echinococcus granulosus | FTZ F1 alpha | 0.0078 | 0.0178 | 0.0549 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0433 | 0.1885 | 0.1885 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0098 | 0.0272 | 0.0839 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0078 | 0.0178 | 0.0178 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 0.0629 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0078 | 0.0178 | 0.0549 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 0.5 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0084 | 0.0204 | 0.0346 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0078 | 0.0178 | 0.0178 |
Echinococcus multilocularis | GPCR, family 2 | 0.0587 | 0.2623 | 0.8098 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0144 | 0.0496 | 0.0841 |
Echinococcus granulosus | isocitrate dehydrogenase NAD | 0.0045 | 0.0016 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.1105 | 0.1105 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0078 | 0.0178 | 0.0301 |
Loa Loa (eye worm) | isocitrate dehydrogenase gamma subunit | 0.0045 | 0.0016 | 0.0016 |
Schistosoma mansoni | smad1 5 8 and | 0.0144 | 0.0496 | 0.0841 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0078 | 0.0178 | 0.0549 |
Brugia malayi | TAR-binding protein | 0.059 | 0.264 | 0.264 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0078 | 0.0178 | 0.0178 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0078 | 0.0178 | 0.0549 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | Isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.1567 |
Schistosoma mansoni | Smad4 | 0.0065 | 0.0112 | 0.0189 |
Brugia malayi | Pax transcription factor protein 2 | 0.0242 | 0.0965 | 0.0965 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0367 | 0.1567 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 0.5 |
Entamoeba histolytica | tartrate dehydrogenase, putative | 0.0045 | 0.0016 | 0.5 |
Echinococcus multilocularis | glycosyltransferase protein LARGE2 | 0.0077 | 0.0171 | 0.0529 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0078 | 0.0178 | 0.0775 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0078 | 0.0178 | 0.0178 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 1 |
Brugia malayi | MH1 domain containing protein | 0.008 | 0.0185 | 0.0185 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0367 | 0.1567 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0144 | 0.0496 | 0.0496 |
Leishmania major | hypothetical protein, conserved | 0.0218 | 0.0851 | 0.5383 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0367 | 0.1567 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0587 | 0.2623 | 0.4447 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | MH1 domain containing protein | 0.008 | 0.0185 | 0.0185 |
Echinococcus granulosus | Glycosyl transferase family 8 | 0.008 | 0.0183 | 0.0567 |
Onchocerca volvulus | 0.0078 | 0.0178 | 0.0775 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0078 | 0.0178 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0185 | 0.0185 |
Schistosoma mansoni | hypothetical protein | 0.0587 | 0.2623 | 0.4447 |
Echinococcus multilocularis | glycosyltransferase protein LARGE2 | 0.0077 | 0.0171 | 0.0529 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0715 | 0.3239 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0587 | 0.2623 | 0.8098 |
Schistosoma mansoni | hypothetical protein | 0.0587 | 0.2623 | 0.4447 |
Echinococcus multilocularis | tar DNA binding protein | 0.059 | 0.264 | 0.815 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.1854 | 0.872 | 0.872 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0065 | 0.0112 | 0.0344 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 0.5 |
Trichomonas vaginalis | isocitrate dehydrogenase, putative | 0.0045 | 0.0016 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0218 | 0.0851 | 0.4745 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0055 | 0.0065 | 0.0319 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.4839 |
Brugia malayi | hypothetical protein | 0.0141 | 0.0479 | 0.0479 |
Brugia malayi | MH1 domain containing protein | 0.0144 | 0.0496 | 0.0496 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0078 | 0.0178 | 0.0178 |
Schistosoma mansoni | nuclear hormone receptor | 0.0078 | 0.0178 | 0.0301 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.4839 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | nuclear receptor NHR-88 | 0.0078 | 0.0178 | 0.0178 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0078 | 0.0178 | 0.0549 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.1854 | 0.872 | 0.872 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0291 | 0.1203 | 0.3713 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0078 | 0.0178 | 0.0549 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0587 | 0.2623 | 0.2623 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0078 | 0.0178 | 0.0301 |
Brugia malayi | steroid hormone receptor | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | RNA binding protein | 0.059 | 0.264 | 0.264 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.2669 | 0.2669 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0078 | 0.0178 | 0.0549 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0078 | 0.0178 | 0.0301 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0242 | 0.0965 | 0.0965 |
Loa Loa (eye worm) | hypothetical protein | 0.1854 | 0.872 | 0.872 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0144 | 0.0496 | 0.1531 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD+) | 0.0045 | 0.0016 | 0.0048 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0065 | 0.0112 | 0.0344 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0367 | 0.1567 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0055 | 0.0065 | 0.2629 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0367 | 0.1567 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0078 | 0.0178 | 0.0301 |
Brugia malayi | Isocitrate dehydrogenase subunit gamma, mitochondrial precursor | 0.0045 | 0.0016 | 0.0016 |
Brugia malayi | RNA binding protein | 0.059 | 0.264 | 0.264 |
Echinococcus multilocularis | glycosyltransferase protein LARGE2 | 0.0077 | 0.0171 | 0.0529 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.059 | 0.264 | 0.264 |
Schistosoma mansoni | coup transcription factor | 0.0078 | 0.0178 | 0.0301 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0218 | 0.0851 | 0.4745 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0078 | 0.0178 | 0.0301 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0272 | 0.0461 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0715 | 0.3239 | 0.3239 |
Loa Loa (eye worm) | TAR-binding protein | 0.059 | 0.264 | 0.264 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0078 | 0.0178 | 0.0178 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0078 | 0.0178 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0178 | 0.0178 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0587 | 0.2623 | 0.8098 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0204 | 0.0204 |
Brugia malayi | MH1 domain containing protein | 0.0144 | 0.0496 | 0.0496 |
Echinococcus multilocularis | smad | 0.0144 | 0.0496 | 0.1531 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0078 | 0.0178 | 0.0178 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0078 | 0.0178 | 0.0301 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0367 | 0.1567 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0078 | 0.0178 | 0.0178 |
Echinococcus granulosus | Smad4 | 0.0144 | 0.0496 | 0.1531 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | glycosyl transferase family 8 protein | 0.008 | 0.0183 | 0.0183 |
Brugia malayi | MH2 domain containing protein | 0.0144 | 0.0496 | 0.0496 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0059 | 0.0085 | 0.0262 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0078 | 0.0178 | 0.0549 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0078 | 0.0178 | 0.0549 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0055 | 0.0065 | 0.0201 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0144 | 0.0496 | 0.1531 |
Brugia malayi | hypothetical protein | 0.0218 | 0.0851 | 0.0851 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0178 | 0.0178 |
Echinococcus granulosus | smad | 0.0144 | 0.0496 | 0.1531 |
Schistosoma mansoni | smad1 5 8 and | 0.0144 | 0.0496 | 0.0841 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0367 | 0.1567 | 1 |
Echinococcus granulosus | glycosyltransferase protein LARGE2 | 0.0077 | 0.0171 | 0.0529 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.1567 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0587 | 0.2623 | 0.2623 |
Loa Loa (eye worm) | nuclear factor I | 0.008 | 0.0185 | 0.0185 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0078 | 0.0178 | 0.0775 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.0851 | 0.0851 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0144 | 0.0496 | 0.0496 |
Schistosoma mansoni | isocitrate dehydrogenase | 0.0045 | 0.0016 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0587 | 0.2623 | 0.2623 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.1854 | 0.872 | 0.872 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0578 | 0.2579 | 0.7963 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0055 | 0.0065 | 0.0201 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0715 | 0.3239 | 1 |
Brugia malayi | Smad1 | 0.0144 | 0.0496 | 0.0496 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit beta, mitochondrial | 0.0045 | 0.0016 | 0.0016 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0218 | 0.0851 | 0.4745 |
Schistosoma mansoni | smad | 0.0144 | 0.0496 | 0.0841 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0144 | 0.0496 | 0.1531 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0367 | 0.1567 | 0.4839 |
Schistosoma mansoni | unc-13 (munc13) | 0.0045 | 0.0016 | 0.0026 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0578 | 0.2579 | 0.7963 |
Schistosoma mansoni | smad1 5 8 and | 0.0144 | 0.0496 | 0.0841 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.2658 |
Echinococcus multilocularis | isocitrate dehydrogenase (NAD) subunit | 0.0045 | 0.0016 | 0.0048 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0578 | 0.2579 | 0.2579 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0078 | 0.0178 | 0.0549 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.1268 | 0.5898 | 0.5898 |
Schistosoma mansoni | Smad4 | 0.0144 | 0.0496 | 0.0841 |
Schistosoma mansoni | hypothetical protein | 0.0587 | 0.2623 | 0.4447 |
Brugia malayi | Glycosyl transferase family 8 protein | 0.008 | 0.0183 | 0.0183 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | ecdysteroid receptor | 0.0078 | 0.0178 | 0.0178 |
Brugia malayi | MH2 domain containing protein | 0.0065 | 0.0112 | 0.0112 |
Brugia malayi | isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.1567 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0055 | 0.0065 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0016 | 0.0016 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.4839 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0541 | 0.2402 | 0.2402 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.0204 | 1 |
Echinococcus multilocularis | Glycosyltransferase protein LARGE1 | 0.0059 | 0.0085 | 0.0262 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0065 | 0.0112 | 0.0112 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0078 | 0.0178 | 0.0178 |
Echinococcus granulosus | isocitrate dehydrogenase NAD subunit | 0.0045 | 0.0016 | 0.0048 |
Schistosoma mansoni | tar DNA-binding protein | 0.059 | 0.264 | 0.4476 |
Echinococcus granulosus | tar DNA binding protein | 0.059 | 0.264 | 0.815 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0367 | 0.1567 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0587 | 0.2623 | 0.8098 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0065 | 0.0112 | 0.0344 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0291 | 0.1203 | 0.1203 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0078 | 0.0178 | 0.0549 |
Schistosoma mansoni | hypothetical protein | 0.1268 | 0.5898 | 1 |
Onchocerca volvulus | 0.0242 | 0.0965 | 1 | |
Echinococcus multilocularis | Glycosyl transferase, family 8 | 0.008 | 0.0183 | 0.0567 |
Loa Loa (eye worm) | Smad1 | 0.0144 | 0.0496 | 0.0496 |
Schistosoma mansoni | tar DNA-binding protein | 0.059 | 0.264 | 0.4476 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0098 | 0.0272 | 0.0839 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0078 | 0.0178 | 0.0549 |
Schistosoma mansoni | tyrosine kinase | 0.0705 | 0.319 | 0.5408 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0065 | 0.0112 | 0.0344 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0078 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.2121 | 1 | 1 |
Brugia malayi | isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | 0.0045 | 0.0016 | 0.0016 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.4839 |
Schistosoma mansoni | Smad4 | 0.0065 | 0.0112 | 0.0189 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0078 | 0.0178 | 0.0775 |
Schistosoma mansoni | smad | 0.0065 | 0.0112 | 0.0189 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0367 | 0.1567 | 0.4839 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0144 | 0.0496 | 0.0496 |
Schistosoma mansoni | thyroid hormone receptor | 0.0078 | 0.0178 | 0.0301 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0367 | 0.1567 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1268 | 0.5898 | 0.5898 |
Schistosoma mansoni | tar DNA-binding protein | 0.059 | 0.264 | 0.4476 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0065 | 0.0112 | 0.0112 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0078 | 0.0178 | 0.0178 |
Schistosoma mansoni | tar DNA-binding protein | 0.059 | 0.264 | 0.4476 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0144 | 0.0496 | 0.1531 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0218 | 0.0851 | 0.4745 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0078 | 0.0178 | 0.0549 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0367 | 0.1567 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0536 | 0.238 | 0.238 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0112 | 0.0112 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0078 | 0.0178 | 0.0178 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0078 | 0.0178 | 0.0549 |
Echinococcus multilocularis | Smad4 | 0.0144 | 0.0496 | 0.1531 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0596 | 0.2669 | 0.2669 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0078 | 0.0178 | 0.0549 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0178 | 0.0178 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.475 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.315 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.96 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.943 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.937 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.835 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.817 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.714 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.7 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.642 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.605 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | = 3.09 uM | Tested for cytotoxicity against DMS 273 (small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 3.09 uM | Tested for cytotoxicity against DMS 273 (small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 3.7 uM | Tested for cytotoxicity against human cancer cell lines HL-60(TB) (leukemia) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 3.7 uM | Tested for cytotoxicity against human cancer cell lines HL-60(TB) (leukemia) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 3.88 uM | Tested for cytotoxicity against COLO 205 (colon cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 3.88 uM | Tested for cytotoxicity against COLO 205 (colon cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 4.68 uM | Tested for cytotoxicity against NCI-H522 (non-small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 4.68 uM | Tested for cytotoxicity against NCI-H522 (non-small-cell lung cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 5.26 uM | Tested for cytotoxicity against M14 melanoma | ChEMBL. | 8410995 |
GI50 (functional) | = 5.26 uM | Tested for cytotoxicity against M14 melanoma | ChEMBL. | 8410995 |
GI50 (functional) | = 5.93 uM | Tested for cytotoxicity against OVCAR-3 (ovarian cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 5.93 uM | Tested for cytotoxicity against OVCAR-3 (ovarian cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 7.28 uM | In vitro cytotoxicity against SF-295 (CNS cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 7.28 uM | In vitro cytotoxicity against SF-295 (CNS cancer) cell line. | ChEMBL. | 8410995 |
GI50 (functional) | = 32 uM | Tested for cytotoxicity against CAKI-1 renal cancer | ChEMBL. | 8410995 |
GI50 (functional) | = 32 uM | Tested for cytotoxicity against CAKI-1 renal cancer | ChEMBL. | 8410995 |
IC50 (functional) | > 40 uM | In vitro inhibition of bovine electrophoretically homogeneous tubulin polymerization. | ChEMBL. | 8410995 |
IC50 (functional) | > 40 uM | In vitro inhibition of bovine electrophoretically homogeneous tubulin polymerization. | ChEMBL. | 8410995 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.