TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 729.969 | Formula: C38H59N5O7S
H donors: 5 H acceptors: 6 LogP: 6.98 Rotable bonds: 25
Rule of 5 violations (Lipinski): 2
SMILES: CCOC(=O)[C@@H](CC(C)C)SC[C@@H]([C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1nc[nH]c1)CC1CCCCC1)O
InChi: 1S/C38H59N5O7S/c1-7-49-36(47)33(18-25(2)3)51-23-32(44)29(19-26-14-10-8-11-15-26)41-35(46)31(21-28-22-39-24-40-28)42-34(45)30(20-27-16-12-9-13-17-27)43-37(48)50-38(4,5)6/h9,12-13,16-17,22,24-26,29-33,44H,7-8,10-11,14-15,18-21,23H2,1-6H3,(H,39,40)(H,41,46)(H,42,45)(H,43,48)/t29-,30-,31-,32-,33+/m0/s1
InChiKey: PVTFSFOLZGVZIC-PMUGGPHNSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	renin	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Neospora caninum	Renin, related	Get druggable targets OG5_126885	All targets in OG5_126885
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	Get druggable targets OG5_126885	All targets in OG5_126885
Cryptosporidium hominis	aspartyl protease precursor	Get druggable targets OG5_126885	All targets in OG5_126885
Trichomonas vaginalis	Clan AA, family A1, cathepsin D-like aspartic peptidase	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium falciparum	plasmepsin I	Get druggable targets OG5_126885	All targets in OG5_126885
Candida albicans	vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C)	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium vivax	plasmepsin IV, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma mansoni	cathepsin D (A01 family)	Get druggable targets OG5_126885	All targets in OG5_126885
Neospora caninum	Pepsinogen A1, related	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium yoelii	hypothetical protein	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma japonicum	ko:K01379 cathepsin D [EC3.4.23.5], putative	Get druggable targets OG5_126885	All targets in OG5_126885
Toxoplasma gondii	aspartyl protease ASP1	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium falciparum	plasmepsin IV	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium falciparum	plasmepsin II	Get druggable targets OG5_126885	All targets in OG5_126885
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126885	All targets in OG5_126885
Theileria parva	pepsinogen, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma mansoni	cathepsin D (A01 family)	Get druggable targets OG5_126885	All targets in OG5_126885
Schistosoma japonicum	Cathepsin D precursor, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium yoelii	plasmepsin	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium vivax	aspartyl proteinase, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium knowlesi	aspartyl protease, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Cryptosporidium parvum	membrane bound aspartyl proteinase with a signal peptide plus transmembrane domain	Get druggable targets OG5_126885	All targets in OG5_126885
Toxoplasma gondii	aspartyl proteinase (eimepsin), putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium berghei	plasmepsin IV	Get druggable targets OG5_126885	All targets in OG5_126885
Theileria parva	cathepsin E, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium knowlesi	plasmepsin IV, putative	Get druggable targets OG5_126885	All targets in OG5_126885
Candida albicans	vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C)	Get druggable targets OG5_126885	All targets in OG5_126885
Loa Loa (eye worm)	aspartic protease BmAsp-2	Get druggable targets OG5_126885	All targets in OG5_126885
Babesia bovis	eukaryotic aspartyl protease family protein	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium berghei	plasmepsin VI	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium falciparum	plasmepsin VI	Get druggable targets OG5_126885	All targets in OG5_126885
Plasmodium yoelii	hypothetical protein	Get druggable targets OG5_126885	All targets in OG5_126885

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Plasmodium falciparum	plasmepsin X	renin	406 aa	352 aa	26.4 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0077	0.0382	0.2481
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 20	0.0048	0.0169	0.0169
Giardia lamblia	Kinase, PLK	0.0098	0.0538	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase	0.0048	0.0169	0.0169
Echinococcus granulosus	smad	0.0053	0.0211	0.0211
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0048	0.0169	0.3138
Echinococcus granulosus	guanine nucleotide binding protein subunit	0.006	0.0258	0.0258
Schistosoma mansoni	cytosol alanyl aminopeptidase (M01 family)	0.007	0.0331	0.0331
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	0.0059	0.0252	0.0252
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0197	0.1264	1
Onchocerca volvulus		0.006	0.0258	0.2039
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 22	0.0048	0.0169	0.0169
Echinococcus granulosus	peptidase Clp S14 family	0.005	0.0188	0.0188
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0207	0.1335	0.1335
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 24	0.0048	0.0169	0.0169
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0065	0.03	0.03
Schistosoma mansoni	ubiquitin-specific peptidase 14 (C19 family)	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Onchocerca volvulus		0.007	0.0331	0.2618
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Echinococcus multilocularis	u4:u6.u5 tri snrnp associated protein 2	0.0048	0.0169	0.0169
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 22	0.0048	0.0169	0.0169
Schistosoma mansoni	ubiquitin-specific peptidase 24 (C19 family)	0.0048	0.0169	0.0169
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Onchocerca volvulus		0.0048	0.0169	0.1336
Schistosoma mansoni	GTP-binding protein alpha subunit gna	0.006	0.0258	0.0258
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma brucei	cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0048	0.0169	0.0169
Schistosoma mansoni	smad	0.0053	0.0211	0.0211
Echinococcus granulosus	tar DNA binding protein	0.0665	0.4686	0.4686
Echinococcus multilocularis	tar DNA binding protein	0.0665	0.4686	0.4686
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	CAMK family protein kinase	0.0098	0.0538	1
Echinococcus multilocularis	ubiquitin specific peptidase 42 (C19 family)	0.0048	0.0169	0.0169
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.006	0.0258	0.0258
Schistosoma mansoni	family M1 non-peptidase homologue (M01 family)	0.0045	0.0152	0.0152
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.007	0.0331	0.6147
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Brugia malayi	G-protein alpha subunit	0.006	0.0258	0.0258
Brugia malayi	RNA recognition motif domain containing protein	0.0665	0.4686	0.4686
Loa Loa (eye worm)	hypothetical protein	0.0197	0.1264	0.1264
Toxoplasma gondii	hypothetical protein	0.0048	0.0169	0.1098
Schistosoma mansoni	hypothetical protein	0.0048	0.0169	0.0169
Loa Loa (eye worm)	transcription factor SMAD2	0.0783	0.5546	0.5546
Schistosoma mansoni	ubiquitin-specific peptidase 4 (C19 family)	0.0048	0.0169	0.0169
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase family 2, putative	0.0048	0.0169	0.1098
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 47	0.0048	0.0169	0.0169
Leishmania major	protein kinase, putative,polo-like protein kinase, putative	0.0098	0.0538	0.35
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Onchocerca volvulus		0.006	0.0258	0.2039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Plasmodium vivax	aspartyl proteinase, putative	0.0059	0.0252	0.1639
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.007	0.0331	0.6147
Echinococcus granulosus	mothers against decapentaplegic 5	0.0053	0.0211	0.0211
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 20	0.0048	0.0169	0.0169
Brugia malayi	hypothetical protein	0.007	0.0331	0.0331
Schistosoma mansoni	ubiquitin-specific peptidase 48 (C19 family)	0.0048	0.0169	0.0169
Echinococcus granulosus	Smad4	0.0053	0.0211	0.0211
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0065	0.03	0.03
Brugia malayi	Guanine nucleotide-binding protein alpha-6 subunit, putative	0.006	0.0258	0.0258
Trichomonas vaginalis	CAMK family protein kinase	0.0098	0.0538	1
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0382	0.5
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Echinococcus granulosus	GPCR family 2	0.0065	0.03	0.03
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Schistosoma mansoni	smad1 5 8 and	0.0053	0.0211	0.0211
Trypanosoma cruzi	aminopeptidase, putative	0.007	0.0331	0.2151
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.1391	1	1
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0152	0.0152
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0382	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Schistosoma mansoni	tar DNA-binding protein	0.0665	0.4686	0.4686
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0048	0.0169	0.0169
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	CAMK family protein kinase	0.0098	0.0538	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0141	0.0856	0.0856
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	ubiquitin specific peptidase 30 (C19 family)	0.0048	0.0169	0.0169
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.005	0.0188	0.5
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Schistosoma mansoni	peptidase	0.0048	0.0171	0.0171
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	family C19 unassigned peptidase (C19 family)	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0382	0.0382
Toxoplasma gondii	aspartyl protease ASP1	0.0059	0.0252	0.1639
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.0065	0.03	0.03
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0665	0.4686	0.4686
Brugia malayi	Guanine nucleotide-binding protein alpha-3 subunit, putative	0.006	0.0258	0.0258
Plasmodium falciparum	ataxin-2 like protein, putative	0.0235	0.1538	1
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Echinococcus granulosus	ubiquitin specific peptidase c family	0.0048	0.0169	0.0169
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Brugia malayi	hypothetical protein	0.0048	0.0169	0.0169
Loa Loa (eye worm)	hypothetical protein	0.0235	0.1538	0.1538
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Echinococcus multilocularis	expressed protein	0.006	0.0258	0.0258
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	smad	0.0053	0.0211	0.0211
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0077	0.0382	0.2481
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.006	0.0258	0.0258
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0048	0.0169	0.0169
Loa Loa (eye worm)	aminopeptidase N	0.007	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0048	0.0169	0.0169
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Leishmania major	hypothetical protein, conserved	0.0235	0.1538	1
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.007	0.0331	0.2151
Schistosoma mansoni	hypothetical protein	0.0065	0.03	0.03
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 36	0.0048	0.0169	0.0169
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.1391	1	1
Trichomonas vaginalis	Clan AA, family A1, cathepsin D-like aspartic peptidase	0.0059	0.0252	0.4684
Echinococcus multilocularis	Peptidase M1, membrane alanine aminopeptidase, N terminal	0.007	0.0331	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	ubiquitin-specific peptidase 5 (C19 family)	0.0048	0.0169	0.0169
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.006	0.0258	0.0258
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	gtp binding protein (I) alpha 1subunit	0.006	0.0258	0.0258
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase 46	0.0048	0.0169	0.0169
Echinococcus granulosus	serine:threonine protein kinase PLK1	0.0098	0.0538	0.0538
Plasmodium falciparum	plasmepsin VI	0.0059	0.0252	0.1639
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.0077	0.0382	1
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.1391	1	1
Brugia malayi	Guanine nucleotide-binding protein alpha-12 subunit, putative	0.006	0.0258	0.0258
Schistosoma mansoni	tar DNA-binding protein	0.0665	0.4686	0.4686
Brugia malayi	MH2 domain containing protein	0.0783	0.5546	0.5546
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 14	0.0048	0.0169	0.1098
Brugia malayi	Probable ClpP-like protease	0.0077	0.0382	0.0382
Echinococcus granulosus	expressed protein	0.006	0.0258	0.0258
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Schistosoma mansoni	tar DNA-binding protein	0.0665	0.4686	0.4686
Entamoeba histolytica	G protein alpha subunit, putative	0.006	0.0258	0.2404
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	gtp binding protein I alpha 1subunit	0.006	0.0258	0.0258
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0048	0.0169	0.1098
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma brucei	Aminopeptidase M1, putative	0.007	0.0331	0.2151
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0382	0.2481
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.0077	0.0382	0.0382
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	serine/threonine protein kinase	0.0098	0.0538	0.0538
Schistosoma mansoni	hypothetical protein	0.0065	0.03	0.03
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0152	0.0152
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Brugia malayi	MH2 domain containing protein	0.0053	0.0211	0.0211
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0048	0.0169	0.0169
Loa Loa (eye worm)	G protein alpha subunit 3	0.006	0.0258	0.0258
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.1391	1	1
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.006	0.0258	0.0258
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Schistosoma mansoni	ubiquitin-specific peptidase 10 (C19 family)	0.0048	0.0169	0.0169
Brugia malayi	Peptidase family M1 containing protein	0.007	0.0331	0.0331
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	guanine nucleotide-binding protein alpha-12 subunit	0.006	0.0258	0.0258
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.007	0.0331	0.2151
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 14	0.0048	0.0169	0.0169
Brugia malayi	MH1 domain containing protein	0.0053	0.0211	0.0211
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Toxoplasma gondii	ubiquitin specific protease 39 isoform 2, putative	0.0048	0.0169	0.1098
Trypanosoma brucei	polo-like protein kinase	0.0098	0.0538	0.35
Schistosoma mansoni	cathepsin D (A01 family)	0.0174	0.1093	0.1093
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0382	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0048	0.0169	0.0169
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0048	0.0169	0.1098
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0065	0.03	0.03
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0026	0.0014	0.009
Echinococcus multilocularis	ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase	0.0048	0.0169	0.0169
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	CAMK family protein kinase	0.0098	0.0538	1
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Onchocerca volvulus		0.0048	0.0169	0.1336
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0382	0.5
Schistosoma mansoni	ubiquitin-specific peptidase 7 (C19 family)	0.0048	0.0169	0.0169
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Plasmodium falciparum	plasmepsin IV	0.0059	0.0252	0.1639
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.0077	0.0382	0.0382
Schistosoma mansoni	GTP-binding protein (I) alpha subunit gnai	0.006	0.0258	0.0258
Plasmodium vivax	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0048	0.0169	0.1098
Echinococcus multilocularis	Smad4	0.0053	0.0211	0.0211
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0048	0.0169	0.3138
Schistosoma mansoni	GTP-binding protein (q) alpha-11 subunit gna11	0.006	0.0258	0.0258
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.006	0.0258	0.0258
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0105	0.0591	0.0591
Brugia malayi	Smad1	0.0053	0.0211	0.0211
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.1391	1	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 1, putative	0.0048	0.0169	0.1098
Brugia malayi	Peptidase family M1 containing protein	0.007	0.0331	0.0331
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0053	0.0211	0.0211
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.006	0.0258	0.4788
Brugia malayi	RNA binding protein	0.0665	0.4686	0.4686
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma brucei	Aminopeptidase M1, putative	0.007	0.0331	0.2151
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0053	0.0211	0.0211
Echinococcus multilocularis	aminopeptidase N	0.007	0.0331	0.0331
Schistosoma mansoni	hypothetical protein	0.0141	0.0856	0.0856
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	Smad4	0.0053	0.0211	0.0211
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0048	0.0169	0.0169
Toxoplasma gondii	LsmAD domain-containing protein	0.0235	0.1538	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0077	0.0382	0.2481
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Echinococcus multilocularis	guanine nucleotide binding protein subunit	0.006	0.0258	0.0258
Schistosoma mansoni	ubiquitin-specific peptidase 22 (C19 family)	0.0048	0.0169	0.0169
Schistosoma mansoni	smad1 5 8 and	0.0053	0.0211	0.0211
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma cruzi	metallo-peptidase, Clan MA(E) Family M1	0.0045	0.0152	0.0985
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.006	0.0258	0.4788
Schistosoma mansoni	ubiquitin-specific peptidase 30 (C19 family)	0.0048	0.0169	0.0169
Echinococcus multilocularis	ubiquitin specific protease 41	0.0048	0.0169	0.0169
Schistosoma mansoni	peptidase Clp (S14 family)	0.0077	0.0382	0.0382
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 5	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	CAMK family protein kinase	0.0049	0.0176	0.3267
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0048	0.0169	0.0169
Schistosoma mansoni	GTP-binding protein alpha subunit gna	0.006	0.0258	0.0258
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	GTP-binding protein (O) alpha subunit, gnao, putative	0.006	0.0258	0.4788
Trichomonas vaginalis	CAMK family protein kinase	0.0049	0.0176	0.3267
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Echinococcus multilocularis	expressed protein	0.0048	0.0169	0.0169
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0048	0.0169	0.0169
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 24	0.0048	0.0169	0.0169
Loa Loa (eye worm)	guanine nucleotide-binding protein alpha-6 subunit	0.006	0.0258	0.0258
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Echinococcus multilocularis	peptidase Clp (S14 family)	0.005	0.0188	0.0188
Schistosoma mansoni	hypothetical protein	0.0065	0.03	0.03
Trypanosoma cruzi	Aminopeptidase M1, putative	0.007	0.0331	0.2151
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase family 2 protein	0.0048	0.0169	0.1098
Brugia malayi	MH1 domain containing protein	0.0029	0.0036	0.0036
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.005	0.0188	0.5
Schistosoma mansoni	hypothetical protein	0.0105	0.0591	0.0591
Trypanosoma cruzi	polo-like protein kinase, putative	0.0098	0.0538	0.35
Brugia malayi	MH1 domain containing protein	0.0053	0.0211	0.0211
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	guanine nucleotide binding protein G protein	0.006	0.0258	0.0258
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0048	0.0169	0.0169
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0048	0.0169	0.0169
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.007	0.0331	0.0331
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Brugia malayi	hypothetical protein	0.0235	0.1538	0.1538
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0059	0.0252	0.0252
Trypanosoma cruzi	PAB1-binding protein , putative	0.0235	0.1538	1
Brugia malayi	MH1 domain containing protein	0.0029	0.0036	0.0036
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	0.0059	0.0252	0.0252
Plasmodium falciparum	plasmepsin II	0.0059	0.0252	0.1639
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.006	0.0258	0.0258
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0065	0.03	0.03
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 16	0.0048	0.0169	0.0169
Onchocerca volvulus	Serine\/threonine kinase homolog	0.0098	0.0538	0.4259
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Brugia malayi	MH2 domain containing protein	0.0053	0.0211	0.0211
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Schistosoma mansoni	ubiquitin-specific peptidase 16 (C19 family)	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Toxoplasma gondii	aspartyl proteinase (eimepsin), putative	0.0059	0.0252	0.1639
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.006	0.0258	0.0258
Schistosoma mansoni	cathepsin D (A01 family)	0.0174	0.1093	0.1093
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.1391	1	1
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 36	0.0048	0.0169	0.0169
Echinococcus multilocularis	serine:threonine protein kinase PLK1	0.0098	0.0538	0.0538
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Toxoplasma gondii	hypothetical protein	0.0026	0.0014	0.009
Schistosoma mansoni	ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	u4:u6.u5 tri snrnp associated protein 2	0.0048	0.0169	0.0169
Schistosoma mansoni	family C19 non-peptidase homologue (C19 family)	0.0048	0.0169	0.0169
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0856	0.0856
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)	0.005	0.0188	0.4744
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 12	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Brugia malayi	hypothetical protein	0.0152	0.093	0.093
Loa Loa (eye worm)	MH2 domain-containing protein	0.0053	0.0211	0.0211
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0382	1
Entamoeba histolytica	aminopeptidase, putative	0.007	0.0331	0.4385
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.006	0.0258	0.4788
Toxoplasma gondii	UBA/TS-N domain-containing protein	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Onchocerca volvulus		0.006	0.0258	0.2039
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Loa Loa (eye worm)	ubiquitin specific peptidase 39	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Echinococcus granulosus	guanine nucleotide binding protein G protein	0.006	0.0258	0.0258
Schistosoma mansoni	GTP-binding protein (I) alpha-1subunit gnai1	0.006	0.0258	0.0258
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.1391	1	1
Echinococcus granulosus	aminopeptidase N	0.007	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0152	0.0152
Plasmodium vivax	ubiquitin specific protease, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Onchocerca volvulus		0.007	0.0331	0.2618
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Schistosoma mansoni	GTP-binding protein (I) alpha-1subunit gnai1	0.006	0.0258	0.0258
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Schistosoma mansoni	calpain-7 (C02 family)	0.0048	0.0169	0.0169
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Trypanosoma cruzi	polo-like protein kinase, putative	0.0098	0.0538	0.35
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Toxoplasma gondii	ubiquitin-specific protease USP4	0.0048	0.0169	0.1098
Echinococcus granulosus	Ubiquitin carboxyl terminal hydrolase 48	0.0048	0.0169	0.0169
Brugia malayi	serine/threonine-protein kinase plk-2	0.0098	0.0538	0.0538
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0053	0.0211	0.0211
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 16	0.0048	0.0169	0.0169
Loa Loa (eye worm)	hypothetical protein	0.006	0.0258	0.0258
Plasmodium falciparum	plasmepsin I	0.0059	0.0252	0.1639
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	ubiquitin-specific peptidase 45 (C19 family)	0.0048	0.0169	0.0169
Brugia malayi	guanine nucleotide-binding protein G(o), alpha subunit, putative	0.006	0.0258	0.0258
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0048	0.0169	0.1098
Loa Loa (eye worm)	MH1 domain-containing protein	0.0053	0.0211	0.0211
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	GTP-binding protein (q) alpha-11 subunit gna11	0.006	0.0258	0.0258
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Loa Loa (eye worm)	TAR-binding protein	0.0665	0.4686	0.4686
Schistosoma mansoni	kinase	0.005	0.0185	0.0185
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Echinococcus multilocularis	Ubiquitin carboxyl terminal hydrolase 48	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 47	0.0048	0.0169	0.0169
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0207	0.1335	0.1335
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	GTP-binding protein (z) alpha subunit, gnaz, putative	0.006	0.0258	0.4788
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Schistosoma mansoni	tar DNA-binding protein	0.0665	0.4686	0.4686
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0026	0.0014	0.009
Schistosoma mansoni	calpain-7 (C02 family)	0.0048	0.0169	0.0169
Plasmodium falciparum	ubiquitin specific protease, putative	0.0048	0.0169	0.1098
Leishmania major	ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Echinococcus multilocularis	guanine nucleotide binding protein (G protein)	0.006	0.0258	0.0258
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Onchocerca volvulus		0.0048	0.0169	0.1336
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0098	0.0538	1
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Brugia malayi	Guanine nucleotide-binding protein alpha-3 subunit, putative	0.006	0.0258	0.0258
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Plasmodium falciparum	ubiquitin specific protease, putative	0.0048	0.0169	0.1098
Plasmodium falciparum	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0053	0.0211	0.0211
Loa Loa (eye worm)	aspartic protease BmAsp-2	0.0059	0.0252	0.0252
Loa Loa (eye worm)	RNA binding protein	0.0665	0.4686	0.4686
Plasmodium vivax	hypothetical protein, conserved	0.0048	0.0169	0.1098
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0048	0.0169	0.1098
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Echinococcus granulosus	5'partial\|Ubiquitin carboxyl terminal hydrolase 48	0.0048	0.0169	0.0169
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0065	0.03	0.03
Schistosoma mansoni	ubiquitin-specific peptidase 44 (C19 family)	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Brugia malayi	TAR-binding protein	0.0665	0.4686	0.4686
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0048	0.0169	0.0169
Schistosoma mansoni	ubiquitin-specific peptidase 46 (C19 family)	0.0048	0.0169	0.0169
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	G protein (olf) alpha subunit, gnal, putative	0.006	0.0258	0.4788
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Mycobacterium ulcerans	aminopeptidase N PepN	0.007	0.0331	0.8672
Plasmodium vivax	plasmepsin IV, putative	0.0059	0.0252	0.1639
Trichomonas vaginalis	GTP-binding protein (q) alpha-11 subunit, gna11, putative	0.006	0.0258	0.4788
Loa Loa (eye worm)	Smad1	0.0053	0.0211	0.0211
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0048	0.0169	0.0169
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.0169
Echinococcus granulosus	ubiquitin specific protease 41	0.0048	0.0169	0.0169
Plasmodium falciparum	ataxin-2 like protein, putative	0.0235	0.1538	1
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0252	0.0252
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Schistosoma mansoni	smad1 5 8 and	0.0053	0.0211	0.0211
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	GTP-binding protein alpha subunit	0.006	0.0258	0.0258
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.007	0.0331	0.2151
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Schistosoma mansoni	hypothetical protein	0.0065	0.03	0.03
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 5	0.0048	0.0169	0.0169
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0065	0.03	0.03
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma cruzi	PAB1-binding protein , putative	0.0235	0.1538	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0048	0.0169	0.0169
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0382	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma brucei	metallo-peptidase, Clan MA(E) Family M1	0.007	0.0331	0.2151
Echinococcus multilocularis	GPCR, family 2	0.0065	0.03	0.03
Trypanosoma brucei	PAB1-binding protein , putative	0.0235	0.1538	1
Loa Loa (eye worm)	hypothetical protein	0.0207	0.1335	0.1335
Brugia malayi	Latrophilin receptor protein 2	0.0065	0.03	0.03
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	CAMK family protein kinase	0.0098	0.0538	1
Brugia malayi	guanine nucleotide-binding protein G-o protein alpha subunit	0.006	0.0258	0.0258
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Brugia malayi	GTP-binding regulatory protein alpha chain - starfish, putative	0.006	0.0258	0.0258
Echinococcus multilocularis	guanine nucleotide binding protein subunit	0.006	0.0258	0.0258
Brugia malayi	hypothetical protein	0.006	0.0258	0.0258
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.1391	1	1
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0045	0.0152	0.0152
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0048	0.0169	0.3138
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0105	0.0591	0.0591
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Plasmodium vivax	ataxin-2 like protein, putative	0.0235	0.1538	1
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Brugia malayi	guanine nucleotide-binding protein alpha-3 subunit, putative	0.006	0.0258	0.0258
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Echinococcus granulosus	guanine nucleotide binding protein subunit	0.006	0.0258	0.0258
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	GTP-binding protein alpha subunit	0.006	0.0258	0.0258
Loa Loa (eye worm)	heterotrimeric G protein alpha subunit	0.006	0.0258	0.0258
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 23	0.0048	0.0169	0.0169
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0048	0.0169	0.3138
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.007	0.0331	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0169	0.0169
Brugia malayi	ubiquitin specific protease 14	0.0048	0.0169	0.0169
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0207	0.1335	0.1335
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.006	0.0258	0.4788
Brugia malayi	N-terminal motif family protein	0.0197	0.1264	0.1264
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Schistosoma mansoni	tar DNA-binding protein	0.0665	0.4686	0.4686
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0048	0.0169	0.1098
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0098	0.0538	0.0538
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Schistosoma mansoni	ubiquitin-specific peptidase 42 (C19 family)	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	GTP-binding regulatory protein alpha chain	0.006	0.0258	0.0258
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0048	0.0169	0.1098
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0048	0.0169	0.1098
Echinococcus multilocularis	guanine nucleotide binding protein (G protein)	0.006	0.0258	0.0258
Loa Loa (eye worm)	nuclear factor I	0.0029	0.0036	0.0036
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Brugia malayi	ubiquitin carboxyl-terminal hydrolase 46	0.0048	0.0169	0.0169
Schistosoma mansoni	trimeric G-protein alpha o subunit	0.006	0.0258	0.0258
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 12	0.0048	0.0169	0.0169
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Trichomonas vaginalis	conserved hypothetical protein	0.0048	0.0169	0.3138
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 14	0.0048	0.0169	0.0169
Trichomonas vaginalis	CAMK family protein kinase	0.0098	0.0538	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Brugia malayi	guanine nucleotide-binding protein alpha-7 subunit, putative	0.006	0.0258	0.0258
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Loa Loa (eye worm)	MH2 domain-containing protein	0.0783	0.5546	0.5546
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	CAMK family protein kinase	0.0098	0.0538	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0048	0.0169	0.0169
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0048	0.0169	0.3138

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 305 nM	Inhibition of human plasma renin	ChEMBL.	1495010
IC50 (binding)	= 305 nM	Inhibition of human plasma renin	ChEMBL.	1495010

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 155501