Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cellular tumor antigen P53 | 0.0102 | 0.0312 | 0.0446 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0042 | 0.0078 | 0.0078 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0078 | 0.0078 |
Trypanosoma cruzi | acetyl-CoA carboxylase, putative | 0.0244 | 0.0873 | 0.2023 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0078 | 0.0116 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.1299 | 0.1857 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0027 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0203 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0203 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0027 | 0.0039 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0022 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.005 | 0.0075 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0078 | 0.0116 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0042 | 0.0078 | 0.0116 |
Trypanosoma cruzi | dihydrolipoamide branched chain transacylase, putative | 0.0063 | 0.0161 | 0.0366 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0029 | 0.0027 | 0.0053 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0042 | 0.0078 | 0.0116 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0078 | 0.0116 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0135 | 0.5157 |
Echinococcus granulosus | FTZ F1 alpha | 0.0042 | 0.0078 | 0.0112 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.005 | 0.0075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0078 | 0.0116 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0155 | 0.0523 | 0.0747 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0686 | 0.2612 | 0.2612 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.1802 | 0.6998 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0022 | 0.0033 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.1304 | 0.504 | 1 |
Leishmania major | carbamoyl-phosphate synthase, putative | 0.0155 | 0.0523 | 0.0717 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0031 | 0.0035 | 0.0074 |
Brugia malayi | MAP kinase sur-1 | 0.0056 | 0.0135 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.005 | 0.0075 |
Brugia malayi | beta-lactamase | 0.0035 | 0.005 | 0.0075 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0107 | 0.0153 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0078 | 0.0116 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0042 | 0.0078 | 0.0112 |
Toxoplasma gondii | pyruvate carboxylase | 0.0686 | 0.2612 | 0.3712 |
Trypanosoma brucei | unspecified product | 0.0451 | 0.1687 | 0.2386 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0099 | 0.011 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0016 | 0.0023 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0016 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0022 | 0.0033 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0686 | 0.2612 | 0.3732 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0686 | 0.2612 | 0.6071 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0708 | 0.1049 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Echinococcus multilocularis | heat shock protein 90 | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0242 | 0.0345 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0099 | 0.0147 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0056 | 0.0135 | 0.0305 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0686 | 0.2612 | 1 |
Toxoplasma gondii | dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase | 0.0063 | 0.0161 | 0.0198 |
Brugia malayi | nuclear hormone receptor | 0.0042 | 0.0078 | 0.0116 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.1738 | 0.675 | 1 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.1802 | 0.6998 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0107 | 0.0159 |
Trypanosoma cruzi | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0063 | 0.0161 | 0.0366 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0039 | 0.0067 | 0.0064 |
Echinococcus multilocularis | dihydrolipoyllysine residue acetyltransferase | 0.0063 | 0.0161 | 0.0161 |
Trypanosoma cruzi | glutamine dependent carbamoyl-phosphate synthase, putative | 0.0155 | 0.0523 | 0.1208 |
Onchocerca volvulus | 0.0029 | 0.0027 | 0.0228 | |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0202 | 0.0708 | 0.1049 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0202 | 0.0708 | 0.623 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Brugia malayi | MH2 domain containing protein | 0.0129 | 0.0421 | 0.0623 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0087 | 0.0254 | 0.0254 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0078 | 0.0116 |
Schistosoma mansoni | dihydrolipoamide S-acetyltransferase | 0.0063 | 0.0161 | 0.023 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.005 | 0.1747 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.1304 | 0.504 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0686 | 0.2612 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0099 | 0.0301 | 0.1116 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0029 | 0.0027 | 0.0039 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.005 | 0.004 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0099 | 0.0301 | 0.1061 |
Schistosoma mansoni | coup transcription factor | 0.0042 | 0.0078 | 0.0112 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.005 | 0.0109 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0042 | 0.0078 | 0.0078 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0042 | 0.0078 | 0.0112 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0078 | 0.0112 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0016 | 0.0023 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.005 | 0.0152 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.005 | 0.0152 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0039 | 0.0067 | 0.0369 |
Echinococcus multilocularis | Biotin lipoyl attachment | 0.0063 | 0.0161 | 0.0161 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0078 | 0.0116 |
Echinococcus granulosus | dihydrolipoyllysine residue acetyltransferase | 0.0063 | 0.0161 | 0.023 |
Entamoeba histolytica | acetyl-coA carboxylase, putative | 0.0307 | 0.1121 | 1 |
Mycobacterium ulcerans | dihydrolipoamide acetyltransferase | 0.0063 | 0.0161 | 0.0519 |
Trypanosoma brucei | pyruvate dehydrogenase complex E3 binding protein, putative | 0.0063 | 0.0161 | 0.0198 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.1802 | 0.6998 | 0.6998 |
Mycobacterium tuberculosis | Probable branched-chain keto acid dehydrogenase E2 component BkdC | 0.0063 | 0.0161 | 0.0577 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0202 | 0.0708 | 0.1012 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0205 | 0.0721 | 0.103 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0042 | 0.0078 | 0.0112 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0129 | 0.0421 | 0.0623 |
Echinococcus granulosus | geminin | 0.0353 | 0.1299 | 0.1857 |
Leishmania major | methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein | 0.0686 | 0.2612 | 0.3712 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0107 | 0.0153 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0099 | 0.0147 |
Onchocerca volvulus | 0.0029 | 0.0027 | 0.0228 | |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0029 | 0.0027 | 0.0006 |
Echinococcus multilocularis | expressed conserved protein | 0.019 | 0.066 | 0.066 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0099 | 0.0141 |
Brugia malayi | Endoplasmin precursor | 0.0039 | 0.0067 | 0.0099 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0078 | 0.0112 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0129 | 0.0421 | 0.0623 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0039 | 0.0067 | 0.0369 |
Plasmodium falciparum | carbamoyl phosphate synthetase | 0.0155 | 0.0523 | 0.1024 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0016 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.005 | 0.0092 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0042 | 0.0078 | 0.0112 |
Leishmania major | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0063 | 0.0161 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.007 | 0.0187 | 0.0677 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0016 | 0.0023 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0099 | 0.0301 | 0.1061 |
Mycobacterium tuberculosis | DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase | 0.0063 | 0.0161 | 0.0577 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0108 | 0.0338 | 0.1258 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0099 | 0.0301 | 0.2507 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0029 | 0.0027 | 0.0784 |
Toxoplasma gondii | carbamoylphosphate synthetase | 0.0155 | 0.0523 | 0.0717 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.005 | 0.0075 |
Echinococcus multilocularis | protein dispatched 1 | 0.0099 | 0.0302 | 0.0302 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0107 | 0.0153 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0135 | 0.5157 |
Mycobacterium ulcerans | branched-chain alpha-keto acid dehydrogenase subunit E2 | 0.0063 | 0.0161 | 0.0519 |
Leishmania major | carboxylase, putative | 0.0686 | 0.2612 | 0.3712 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.0818 | 0.1211 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.005 | 0.0092 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0242 | 0.0345 |
Onchocerca volvulus | 0.0035 | 0.005 | 0.0728 | |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0056 | 0.0135 | 0.0305 |
Plasmodium vivax | carbamoyl phosphate synthetase, putative | 0.0155 | 0.0523 | 0.0997 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0099 | 0.0301 | 0.1061 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0074 | 0.0203 | 0.0191 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0056 | 0.0135 | 0.0192 |
Schistosoma mansoni | endoplasmin | 0.0039 | 0.0067 | 0.0096 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.007 | 0.0187 | 0.0677 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0027 | 0.0039 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Mycobacterium ulcerans | acetyl/propionyl CoA carboxylase subunit beta | 0.0244 | 0.0873 | 0.3273 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0078 | 0.0112 |
Chlamydia trachomatis | biotin carboxylase | 0.0623 | 0.2363 | 1 |
Chlamydia trachomatis | acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | 0.0244 | 0.0873 | 0.3233 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0203 | 0.03 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.005 | 0.0072 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0135 | 0.5157 |
Brugia malayi | AMP-binding enzyme family protein | 0.0099 | 0.0301 | 0.0446 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.005 | 0.005 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0097 | 0.0139 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0686 | 0.2612 | 0.3712 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0087 | 0.0254 | 0.0363 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0099 | 0.0182 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0042 | 0.0078 | 0.1312 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.007 | 0.0187 | 0.0677 |
Wolbachia endosymbiont of Brugia malayi | branched-chain alpha-keto acid dehydrogenase subunit E2 | 0.0063 | 0.0161 | 0.0486 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase precursor, putative | 0.0063 | 0.0161 | 0.0366 |
Echinococcus multilocularis | dihydrolipoyllysine residue succinyltransferase | 0.0063 | 0.0161 | 0.0161 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.005 | 0.0056 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.005 | 0.0092 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0029 | 0.0027 | 0.0006 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0097 | 0.0139 |
Echinococcus granulosus | heat shock protein 90 | 0.0031 | 0.0035 | 0.0051 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.005 | 0.0109 |
Trypanosoma cruzi | glutamine-dependent carbamoyl-phosphate synthetase, putative | 0.0155 | 0.0523 | 0.1208 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0039 | 0.0067 | 0.029 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0108 | 0.0338 | 0.1258 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.005 | 0.0152 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0029 | 0.0027 | 0.0061 |
Trichomonas vaginalis | heat shock protein, putative | 0.0031 | 0.0035 | 0.1144 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0135 | 0.5157 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Toxoplasma gondii | biotin-requiring enzyme domain-containing protein | 0.0063 | 0.0161 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0203 | 0.03 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0029 | 0.0027 | 0.0038 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0042 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | endoplasmin | 0.0039 | 0.0067 | 0.0099 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0099 | 0.0222 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0042 | 0.0078 | 0.0112 |
Schistosoma mansoni | propionyl-CoA carboxylase beta chain mitochondrial precursor | 0.0244 | 0.0873 | 0.1247 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0107 | 0.0159 |
Mycobacterium tuberculosis | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) | 0.0244 | 0.0873 | 0.3314 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0686 | 0.2612 | 0.3732 |
Treponema pallidum | pyruvate carboxylase subunit B | 0.0063 | 0.0161 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0056 | 0.0135 | 0.0199 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0031 | 0.0035 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Plasmodium falciparum | lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 0.0063 | 0.0161 | 0.0305 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0764 | 0.2919 | 0.4171 |
Leishmania major | dihydrolipoamide acetyltransferase precursor, putative | 0.0063 | 0.0161 | 0.0198 |
Schistosoma mansoni | aspartate carbamoyltransferase | 0.0155 | 0.0523 | 0.0747 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0099 | 0.0301 | 0.1061 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0099 | 0.0301 | 0.1061 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.007 | 0.0187 | 0.0677 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0254 | 0.0376 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0056 | 0.0135 | 0.0912 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0078 | 0.0116 |
Schistosoma mansoni | dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase | 0.0063 | 0.0161 | 0.023 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0686 | 0.2612 | 0.3712 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0042 | 0.0078 | 0.0116 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0087 | 0.0254 | 0.0376 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0029 | 0.0027 | 0.0039 |
Leishmania major | dihydrolipoamide branched chain transacylase, putative | 0.0063 | 0.0161 | 0.0198 |
Plasmodium falciparum | dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.0063 | 0.0161 | 0.0305 |
Onchocerca volvulus | 0.0029 | 0.0027 | 0.0228 | |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0029 | 0.0027 | 0.0061 |
Mycobacterium leprae | Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) | 0.0244 | 0.0873 | 0.3273 |
Brugia malayi | hypothetical protein | 0.0147 | 0.0491 | 0.0727 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase, putative | 0.0063 | 0.0161 | 0.0366 |
Giardia lamblia | Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative | 0.0307 | 0.1121 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.005 | 0.0092 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E2 | 0.0063 | 0.0161 | 0.0198 |
Mycobacterium leprae | ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 | 0.0244 | 0.0873 | 0.3273 |
Schistosoma mansoni | lamin | 0.0026 | 0.0016 | 0.0023 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.1802 | 0.6998 | 1 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0031 | 0.0035 | 0.0019 |
Brugia malayi | hypothetical protein | 0.023 | 0.0818 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0161 | 0.0238 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0099 | 0.0301 | 0.2507 |
Echinococcus granulosus | lamin | 0.0026 | 0.0016 | 0.0023 |
Brugia malayi | CHE-14 protein | 0.0087 | 0.0254 | 0.0376 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0099 | 0.0301 | 0.0399 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Echinococcus multilocularis | protein patched | 0.0087 | 0.0254 | 0.0254 |
Mycobacterium leprae | Probable biotinylated protein homolog TB7.3 | 0.0063 | 0.0161 | 0.0519 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.012 | 0.0385 | 0.144 |
Toxoplasma gondii | 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein | 0.0063 | 0.0161 | 0.0198 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0029 | 0.0027 | 0.0061 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0027 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0161 | 0.0238 |
Mycobacterium ulcerans | carbamoyl phosphate synthase large subunit | 0.0155 | 0.0523 | 0.1919 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0312 | 0.0463 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0042 | 0.0078 | 0.0116 |
Leishmania major | dihydrolipoamide acetyltransferase precursorlike protein | 0.0063 | 0.0161 | 0.0198 |
Trypanosoma brucei | dihydrolipoamide acetyltransferase E2 subunit, putative | 0.0063 | 0.0161 | 0.0198 |
Onchocerca volvulus | 0.0102 | 0.0312 | 0.6241 | |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0074 | 0.0203 | 0.0738 |
Plasmodium vivax | heat shock protein 86, putative | 0.0039 | 0.0067 | 0.0089 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0155 | 0.0523 | 0.0747 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0331 | 0.049 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0686 | 0.2612 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.005 | 0.1747 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0078 | 0.0116 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0042 | 0.0078 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0014 | 0.0021 |
Toxoplasma gondii | acyl-CoA carboxyltransferase beta chain, putative | 0.0244 | 0.0873 | 0.1219 |
Schistosoma mansoni | endoplasmin | 0.0039 | 0.0067 | 0.0096 |
Schistosoma mansoni | pyruvate carboxylase | 0.0686 | 0.2612 | 0.3732 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0027 | 0.0039 |
Mycobacterium ulcerans | acetyl-/propionyl-CoA carboxylase subunit beta | 0.0244 | 0.0873 | 0.3273 |
Trypanosoma brucei | glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative | 0.0155 | 0.0523 | 0.0717 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase beta chain | 0.0244 | 0.0873 | 0.0873 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0056 | 0.0135 | 0.0161 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium tuberculosis | Biotinylated protein TB7.3 | 0.0063 | 0.0161 | 0.0577 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0056 | 0.0135 | 0.0305 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0029 | 0.0027 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.1299 | 0.1857 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.0793 | 0.3008 |
Echinococcus granulosus | endoplasmin | 0.0031 | 0.0035 | 0.0051 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0764 | 0.2919 | 0.4171 |
Brugia malayi | Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor | 0.0063 | 0.0161 | 0.0238 |
Plasmodium falciparum | dihydrolipoamide acyltransferase component E2 | 0.0063 | 0.0161 | 0.0305 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0107 | 0.0107 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0078 | 0.0112 |
Plasmodium falciparum | heat shock protein 90 | 0.0039 | 0.0067 | 0.0119 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.1802 | 0.6998 | 1 |
Echinococcus multilocularis | geminin | 0.0353 | 0.1299 | 0.1299 |
Echinococcus multilocularis | endoplasmin | 0.0031 | 0.0035 | 0.0035 |
Leishmania major | propionyl-coa carboxylase beta chain, putative | 0.0244 | 0.0873 | 0.1219 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0099 | 0.0301 | 0.1061 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0029 | 0.0027 | 0.0784 |
Echinococcus granulosus | tumor protein p63 | 0.0694 | 0.2644 | 0.3778 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.005 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0301 | 0.0446 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4 | 0.0244 | 0.0873 | 0.3273 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0027 | 0.0039 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0764 | 0.2919 | 0.2919 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.1115 | 0.4299 | 1 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0031 | 0.0035 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0039 | 0.0067 | 0.0147 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0056 | 0.0135 | 0.0161 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0244 | 0.0873 | 0.2023 |
Schistosoma mansoni | heat shock protein | 0.0039 | 0.0067 | 0.0096 |
Trypanosoma brucei | protein kinase, putative | 0.0056 | 0.0135 | 0.0161 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0074 | 0.0203 | 0.0388 |
Mycobacterium ulcerans | hypothetical protein | 0.0099 | 0.0301 | 0.1061 |
Trichomonas vaginalis | heat shock protein, putative | 0.0039 | 0.0067 | 0.2418 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide acyltransferase E2 component | 0.0063 | 0.0161 | 0.0486 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.005 | 0.0075 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.005 | 0.004 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0027 | 0.0061 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0108 | 0.0338 | 0.1258 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.0818 | 0.1168 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0108 | 0.0338 | 0.1258 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.005 | 0.0152 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.005 | 0.0152 |
Onchocerca volvulus | 0.0035 | 0.005 | 0.0728 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0099 | 0.0301 | 0.2507 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0078 | 0.0112 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0016 | 0.0023 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0022 | 0.003 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0099 | 0.0147 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0099 | 0.0153 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0039 | 0.0067 | 0.0064 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0099 | 0.0153 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.005 | 0.0092 |
Brugia malayi | nuclear receptor NHR-88 | 0.0042 | 0.0078 | 0.0116 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0016 | 0.0016 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Brugia malayi | heat shock protein 90 | 0.0039 | 0.0067 | 0.0099 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0099 | 0.011 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0031 | 0.0035 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0203 | 0.03 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0027 | 0.0053 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0027 | 0.0061 |
Trypanosoma brucei | 2-oxoglutarate dehydrogenase E2 component, putative | 0.0063 | 0.0161 | 0.0198 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0686 | 0.2612 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0099 | 0.0301 | 0.0446 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.005 | 0.1747 |
Brugia malayi | AMP-binding enzyme family protein | 0.0099 | 0.0301 | 0.0446 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0074 | 0.0203 | 0.0682 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.005 | 0.0092 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0078 | 0.0112 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0078 | 0.0078 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0039 | 0.0067 | 0.0147 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0244 | 0.0873 | 0.2023 |
Echinococcus granulosus | expressed conserved protein | 0.019 | 0.066 | 0.0943 |
Mycobacterium tuberculosis | Probable reductase | 0.0108 | 0.0338 | 0.1258 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0031 | 0.0035 | 0.0034 |
Echinococcus granulosus | heat shock protein 90 | 0.0039 | 0.0067 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.005 | 0.0075 |
Trichomonas vaginalis | heat shock protein, putative | 0.0031 | 0.0035 | 0.1144 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0301 | 0.0446 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0039 | 0.0067 | 0.0147 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0016 | 0.0016 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.005 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0029 | 0.0027 | 0.0061 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0029 | 0.0027 | 0.0061 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0099 | 0.0182 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0042 | 0.0078 | 0.1312 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0078 | 0.0116 |
Echinococcus multilocularis | tumor protein p63 | 0.0694 | 0.2644 | 0.2644 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0074 | 0.0203 | 0.036 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.005 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0242 | 0.0345 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0027 | 0.0039 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.012 | 0.0385 | 0.144 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0108 | 0.0338 | 0.1258 |
Wolbachia endosymbiont of Brugia malayi | carbamoyl phosphate synthase large subunit | 0.0155 | 0.0523 | 0.1891 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0078 | 0.0078 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0042 | 0.0078 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0161 | 0.0238 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.005 | 0.0092 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0242 | 0.0345 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.005 | 0.0072 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0686 | 0.2612 | 1 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0029 | 0.0027 | 0.0038 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.1738 | 0.675 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0099 | 0.0301 | 0.1116 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 5 AccD5 | 0.0244 | 0.0873 | 0.3273 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0039 | 0.0067 | 0.0099 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.005 | 0.0075 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0078 | 0.0116 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0078 | 0.0116 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0107 | 0.0153 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0289 | 0.105 | 0.105 |
Onchocerca volvulus | 0.0042 | 0.0078 | 0.1312 | |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0016 | 0.0023 |
Echinococcus granulosus | propionyl coenzyme A carboxylase beta chain | 0.0244 | 0.0873 | 0.1247 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0202 | 0.0708 | 0.0708 |
Schistosoma mansoni | dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase | 0.0063 | 0.0161 | 0.023 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.005 | 0.0072 |
Plasmodium vivax | endoplasmin, putative | 0.0039 | 0.0067 | 0.0089 |
Mycobacterium leprae | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB | 0.0063 | 0.0161 | 0.0519 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.005 | 0.0152 |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.0686 | 0.2612 | 1 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0027 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0016 | 0.0023 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0087 | 0.0254 | 0.0363 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0056 | 0.0135 | 0.0135 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0022 | 0.003 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0029 | 0.0027 | 0.0008 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0099 | 0.011 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0027 | 0.0061 |
Leishmania major | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0244 | 0.0873 | 0.1219 |
Trypanosoma brucei | dihydrolipoamide branched chain transacylase, putative | 0.0063 | 0.0161 | 0.0198 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0031 | 0.0035 | 0.0074 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0042 | 0.0078 | 0.0112 |
Trichomonas vaginalis | heat shock protein, putative | 0.0031 | 0.0035 | 0.1144 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0099 | 0.0339 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0029 | 0.0027 | 0.0038 |
Schistosoma mansoni | nuclear hormone receptor | 0.0042 | 0.0078 | 0.0112 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0107 | 0.0153 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.005 | 0.0075 |
Schistosoma mansoni | patched 1 | 0.0087 | 0.0254 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0301 | 0.0446 |
Schistosoma mansoni | heat shock protein | 0.0039 | 0.0067 | 0.0096 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0087 | 0.0254 | 1 |
Wolbachia endosymbiont of Brugia malayi | Acetyl-CoA carboxylase, carboxyltransferase component | 0.0244 | 0.0873 | 0.325 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0686 | 0.2612 | 0.3732 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0078 | 0.0116 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0108 | 0.0338 | 0.1204 |
Mycobacterium ulcerans | acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 | 0.0244 | 0.0873 | 0.3273 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0099 | 0.0301 | 0.0399 |
Onchocerca volvulus | 0.0047 | 0.0097 | 0.1713 | |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0039 | 0.0067 | 0.0147 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Echinococcus granulosus | dihydrolipoyllysine residue succinyltransferase | 0.0063 | 0.0161 | 0.023 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0099 | 0.0301 | 0.1061 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0099 | 0.0301 | 0.1061 |
Trypanosoma cruzi | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0063 | 0.0161 | 0.0366 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0078 | 0.0112 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0029 | 0.0027 | 0.0027 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0042 | 0.0078 | 0.0078 |
Echinococcus granulosus | Biotin lipoyl attachment | 0.0063 | 0.0161 | 0.023 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Echinococcus multilocularis | heat shock protein 90 | 0.0039 | 0.0067 | 0.0067 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0099 | 0.0099 |
Plasmodium vivax | dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative | 0.0063 | 0.0161 | 0.0276 |
Onchocerca volvulus | 0.0099 | 0.0301 | 0.6002 | |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.1802 | 0.6998 | 1 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.1802 | 0.6998 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0039 | 0.0067 | 0.0064 |
Echinococcus multilocularis | heat shock protein | 0.0039 | 0.0067 | 0.0067 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.0818 | 0.0818 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0056 | 0.0135 | 0.0161 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0029 | 0.0027 | 0.0039 |
Mycobacterium ulcerans | hypothetical protein | 0.0063 | 0.0161 | 0.0519 |
Trypanosoma brucei | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0244 | 0.0873 | 0.1219 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0078 | 0.0116 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0039 | 0.0067 | 0.0064 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.005 | 0.1747 |
Onchocerca volvulus | 0.0147 | 0.0491 | 1 | |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0039 | 0.0067 | 0.0147 |
Loa Loa (eye worm) | oxidoreductase | 0.0029 | 0.0027 | 0.0039 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0056 | 0.0135 | 0.0161 |
Mycobacterium tuberculosis | Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 | 0.0244 | 0.0873 | 0.3314 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0029 | 0.0027 | 0.0006 |
Trypanosoma brucei | heat shock protein, putative | 0.0039 | 0.0067 | 0.0064 |
Plasmodium vivax | lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative | 0.0063 | 0.0161 | 0.0276 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0099 | 0.0301 | 0.1061 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0097 | 0.0144 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0022 | 0.0043 |
Mycobacterium leprae | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) | 0.0244 | 0.0873 | 0.3273 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0056 | 0.0135 | 0.0305 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0686 | 0.2612 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0029 | 0.0027 | 0.0039 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0042 | 0.0078 | 0.0112 |
Echinococcus granulosus | heat shock protein | 0.0039 | 0.0067 | 0.0096 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0042 | 0.0078 | 0.0112 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0078 | 0.0116 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0042 | 0.0078 | 0.1312 |
Toxoplasma gondii | dihydrolipoamide acyltransferase, putative | 0.0063 | 0.0161 | 0.0198 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0056 | 0.0135 | 0.0192 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0029 | 0.0027 | 0.0053 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.012 | 0.0385 | 0.1388 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.005 | 0.0152 |
Leishmania major | heat shock protein 83-1 | 0.0039 | 0.0067 | 0.0064 |
Brugia malayi | steroid hormone receptor | 0.0042 | 0.0078 | 0.0116 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0099 | 0.0301 | 0.0399 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0042 | 0.0078 | 0.0112 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0686 | 0.2612 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0099 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.005 | 0.1747 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.005 | 0.0152 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.012 | 0.0385 | 0.144 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0039 | 0.0067 | 0.0064 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4_2 | 0.0244 | 0.0873 | 0.3273 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.005 | 0.1747 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0686 | 0.2612 | 0.6071 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0289 | 0.105 | 0.15 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0056 | 0.0135 | 0.0192 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0027 | 0.0061 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0029 | 0.0027 | 0.0053 |
Toxoplasma gondii | propionate-CoA ligase | 0.0029 | 0.0027 | 0.0006 |
Onchocerca volvulus | 0.0029 | 0.0027 | 0.0228 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.005 | 0.0152 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0029 | 0.0027 | 0.0061 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.005 | 0.0152 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0056 | 0.0135 | 0.0135 |
Schistosoma mansoni | lamin | 0.0026 | 0.0016 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0078 | 0.0116 |
Schistosoma mansoni | dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase | 0.0063 | 0.0161 | 0.023 |
Brugia malayi | dihydrolipoamide S-acetyltransferase precursor, putative | 0.0063 | 0.0161 | 0.0238 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0029 | 0.0027 | 0.0006 |
Onchocerca volvulus | 0.0035 | 0.005 | 0.0728 | |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase precursor, putative | 0.0063 | 0.0161 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.005 | 0.0075 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0029 | 0.0027 | 0.0061 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0078 | 0.0078 |
Trypanosoma cruzi | dihydrolipoamide branched chain transacylase, putative | 0.0063 | 0.0161 | 0.0366 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0042 | 0.0078 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0491 | 0.0727 |
Brugia malayi | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta | 0.0063 | 0.0161 | 0.0238 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0107 | 0.0107 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0078 | 0.0078 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 20 uM | Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay | ChEMBL. | 21381696 |
IC50 (functional) | > 20 uM | Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay | ChEMBL. | 21381696 |
IC50 (functional) | > 20 uM | Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay | ChEMBL. | 21381696 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.