Detailed information for compound 1555877

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 322.315 | Formula: C18H14N2O4
  • H donors: 4 H acceptors: 4 LogP: 2.91 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cccc2c1cc(O)cc2)Nc1cccc(c1)C(=O)O
  • InChi: 1S/C18H14N2O4/c21-14-8-7-11-3-2-6-16(15(11)10-14)20-18(24)19-13-5-1-4-12(9-13)17(22)23/h1-10,21H,(H,22,23)(H2,19,20,24)
  • InChiKey: HESPAXPTHYPSLE-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens transient receptor potential cation channel, subfamily V, member 1 Starlite/ChEMBL References
Rattus norvegicus Vanilloid receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0008 0.0034 0.0037
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0034 0.0034
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0425 0.0491
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0021 0.0716 0.1737
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.1366 0.3314
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0565 0.0711
Loa Loa (eye worm) ion channel NompC 0.0008 0.0034 0.0039
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0071 0.0071
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Echinococcus granulosus sodium leak channel non selective protein 0.0008 0.0034 0.0034
Schistosoma mansoni nuclear receptor 0.0015 0.0425 0.0425
Leishmania major hypothetical protein, conserved 0.0022 0.0747 0.0827
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.02 0.0221
Leishmania major monoglyceride lipase, putative 0.0062 0.2821 0.3122
Trypanosoma cruzi PAB1-binding protein , putative 0.0022 0.0747 0.0827
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.1313 0.1515
Brugia malayi Pax transcription activation domain interacting protein 0.0008 0.0068 0.0079
Plasmodium falciparum lysophospholipase, putative 0.0062 0.2821 0.3818
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0425 0.0559
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0008 0.0034 0.0039
Echinococcus granulosus chromobox protein 2 0.001 0.0137 0.0137
Chlamydia trachomatis DNA ligase 0.0008 0.0068 0.0182
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0008 0.0068 0.0124
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0082 0.3854 0.3854
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0068 0.0165
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0008 0.0068 0.0138
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0071 0.0051
Trichomonas vaginalis heat shock protein, putative 0.0037 0.1534 0.3722
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0027 0.0999 0.1105
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.052 0.0601
Mycobacterium tuberculosis Probable oxidoreductase 0.0103 0.4933 0.8899
Trypanosoma brucei unspecified product 0.0043 0.184 0.2036
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Echinococcus multilocularis muscleblind protein 0.0176 0.8663 0.8663
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.1313 0.1313
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0034 0.0034
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.0054 0.0063
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.1313 0.1515
Trypanosoma brucei monoglyceride lipase, putative 0.0062 0.2821 0.3122
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0425 0.0425
Brugia malayi polk-prov protein 0.0019 0.0626 0.0723
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0008 0.0034 0.0039
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.2833 0.3135
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0034 0.0034
Plasmodium vivax heat shock protein 90, putative 0.0026 0.0979 0.128
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0053 0.2325 0.3149
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0034 0.0034
Echinococcus granulosus short transient receptor potential channel 6 0.0008 0.0049 0.0049
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0034 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0014 0.0357 0.065
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0626 0.0693
Brugia malayi hypothetical protein 0.0017 0.052 0.0601
Brugia malayi nuclear receptor RXR 0.0015 0.0425 0.0491
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.052 0.052
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0062 0.2833 0.2833
Loa Loa (eye worm) hypothetical protein 0.001 0.0137 0.0158
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0425 0.0425
Schistosoma mansoni chromodomain helicase DNA binding protein 0.001 0.0137 0.0137
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.008 0.3755 0.6828
Brugia malayi Cyclic-nucleotide gated cation channel 0.0008 0.0034 0.0039
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0425 0.0491
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0357 0.0867
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Trypanosoma brucei beta lactamase 0.0055 0.2449 0.271
Leishmania major DNA polymerase eta, putative 0.0123 0.5932 0.6564
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0008 0.0034 0.0034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.2448 0.2826
Plasmodium vivax endoplasmin, putative 0.004 0.1658 0.2217
Brugia malayi steroid hormone receptor 0.0033 0.1313 0.1515
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.001 0.0137 0.0137
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.2833 0.5152
Echinococcus multilocularis jumonji domain containing protein 0.0035 0.1426 0.1426
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.2833 0.6874
Echinococcus multilocularis lysine specific demethylase 5A 0.003 0.1193 0.1193
Echinococcus multilocularis two pore calcium channel protein 1 0.0008 0.0034 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0008 0.0034 0.0039
Plasmodium falciparum heat shock protein 90 0.004 0.1658 0.2217
Plasmodium vivax hypothetical protein, conserved 0.001 0.0137 0.0121
Loa Loa (eye worm) hypothetical protein 0.0025 0.0922 0.1064
Echinococcus granulosus voltage gated potassium channel 0.0008 0.0034 0.0034
Onchocerca volvulus 0.001 0.0137 0.0148
Brugia malayi heat shock protein 90 0.004 0.1658 0.1914
Loa Loa (eye worm) jmjC domain-containing protein 0.0008 0.0049 0.0057
Echinococcus multilocularis Chromobox protein 3 0.001 0.0137 0.0137
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.1313 0.1313
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.02 0.0221
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Echinococcus multilocularis two pore calcium channel protein 2 0.0008 0.0034 0.0034
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Echinococcus granulosus FTZ F1 alpha 0.0033 0.1313 0.1313
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0471 0.0471
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0008 0.0068 0.0165
Loa Loa (eye worm) hypothetical protein 0.0022 0.0747 0.0863
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0026 0.0979 0.0979
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.001 0.0137 0.0121
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0626 0.0693
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0034 0.0082
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0008 0.0034 0.0034
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0008 0.0034 0.0034
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.001 0.0133 0.0133
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0008 0.0034 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.1366 0.1511
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0008 0.0034 0.0034
Brugia malayi jmjC domain containing protein 0.003 0.1193 0.1377
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.1313 0.1515
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.1313 0.1515
Trichomonas vaginalis heat shock protein, putative 0.0034 0.1366 0.3314
Echinococcus multilocularis geminin 0.0202 1 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0425 0.0425
Echinococcus multilocularis potassium large conductance calcium activated 0.0008 0.0034 0.0034
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0357 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Echinococcus multilocularis conserved hypothetical protein 0.0008 0.0034 0.0034
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0031 0.1223 0.1223
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.001 0.0137 0.0142
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.001 0.0137 0.0137
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0034 0.0034
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.06 0.06
Brugia malayi hypothetical protein 0.0144 0.7039 0.8125
Schistosoma mansoni chromobox protein 0.006 0.2713 0.2713
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.1313 0.1313
Echinococcus granulosus Chromo domain 0.001 0.0137 0.0137
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0034 0.0034
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0008 0.0034 0.0034
Trypanosoma cruzi heat shock protein, putative 0.0026 0.0979 0.1083
Brugia malayi hypothetical protein 0.0015 0.0425 0.0491
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.1723 0.1723
Loa Loa (eye worm) hypothetical protein 0.0059 0.2683 0.3097
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0088 0.4122 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0008 0.0054 0.0007
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0357 0.0395
Entamoeba histolytica hypothetical protein 0.0031 0.1223 0.3212
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0008 0.0034 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.3809 0.9239
Loa Loa (eye worm) voltage-gated potassium channel 0.0008 0.0034 0.0039
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0598 0.0598
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Schistosoma mansoni hypothetical protein 0.0019 0.0598 0.0598
Giardia lamblia PHD finger protein 15 0.0025 0.0922 0.2236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.0333
Brugia malayi hypothetical protein 0.0014 0.0352 0.0407
Plasmodium vivax glutathione reductase, putative 0.0041 0.1723 0.2306
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0014 0.0357 0.0952
Echinococcus granulosus TRP transient receptor potential channel 0.0008 0.0034 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0022 0.0747 0.0981
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0034 0.0034
Mycobacterium ulcerans hypothetical protein 0.0021 0.0716 0.1302
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0034 0.0034
Echinococcus granulosus heat shock protein 90 0.0034 0.1366 0.1366
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0103 0.4933 0.8899
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0425 0.0425
Toxoplasma gondii thioredoxin reductase 0.0041 0.1723 0.2322
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0626 0.0693
Schistosoma mansoni nuclear hormone receptor 0.0033 0.1313 0.1313
Trichomonas vaginalis chromobox protein, putative 0.006 0.2713 0.6581
Loa Loa (eye worm) voltage-dependent calcium channel 0.0008 0.0034 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0357 0.1972
Onchocerca volvulus 0.0009 0.0085 0.0074
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.06 0.0471
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0165 0.0191
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.1313 0.1313
Leishmania major DNA polymerase eta, putative 0.008 0.3725 0.4122
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.06 0.0664
Trichomonas vaginalis Heterochromatin protein, putative 0.001 0.0137 0.0333
Schistosoma mansoni DNA helicase recq5 0.0009 0.0071 0.0071
Echinococcus multilocularis peregrin 0.0025 0.0922 0.0922
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0008 0.0068 0.0179
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.2294 0.2648
Brugia malayi hypothetical protein 0.0008 0.0068 0.0079
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.1313 0.1313
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0114 0.5499 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.1313 0.1313
Echinococcus multilocularis citrate lyase subunit beta protein 0.0021 0.0716 0.0716
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.008 0.3755 0.4155
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.052 0.0601
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0922 0.1064
Echinococcus granulosus heat shock protein 0.004 0.1658 0.1658
Schistosoma mansoni jumonji domain containing protein 0.0065 0.2986 0.2986
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.1313 0.1313
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.2448 0.2448
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.1359 0.3298
Brugia malayi PHD-finger family protein 0.0008 0.0054 0.0063
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.3809 0.9239
Echinococcus multilocularis replication factor c subunit 1 0.0008 0.0068 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.3809 0.9239
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.008 0.3755 0.3755
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0025 0.0922 0.0922
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0034 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.02 0.0221
Echinococcus multilocularis GPCR, family 2 0.0019 0.0598 0.0598
Schistosoma mansoni transient receptor potential channel 0.0008 0.0034 0.0034
Brugia malayi conserved hypotetical protein 0.0015 0.0425 0.0491
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0008 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.0183 0.9037 1
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0855 0.2075
Echinococcus multilocularis JmjC domain containing protein 4 0.0008 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.1313 0.1515
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.1313 0.1515
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.06 0.0664
Brugia malayi Associated with TFs and helicases family protein 0.001 0.0137 0.0158
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0026 0.0979 0.0979
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Mycobacterium tuberculosis Conserved protein 0.0021 0.0716 0.0697
Schistosoma mansoni ryanodine receptor related 0.0008 0.0034 0.0034
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0062 0.2821 0.6844
Schistosoma mansoni transcription factor LCR-F1 0.0031 0.1223 0.1223
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0081 0.3809 0.3809
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Brugia malayi glutathione reductase 0.0041 0.1723 0.1989
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.1313 0.1826
Plasmodium falciparum glutathione reductase 0.0041 0.1723 0.2306
Loa Loa (eye worm) jmjC domain-containing protein 0.0008 0.0049 0.0057
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0034 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.1313 0.1515
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0049 0.0049
Brugia malayi serine/threonine-protein kinase plk-2 0.0081 0.3809 0.4396
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Trichomonas vaginalis heat shock protein, putative 0.004 0.1658 0.4023
Loa Loa (eye worm) CHromoDomain protein family member 0.001 0.0137 0.0158
Echinococcus multilocularis voltage gated potassium channel 0.0008 0.0034 0.0034
Brugia malayi M-phase phosphoprotein, mpp8 0.001 0.0137 0.0158
Mycobacterium tuberculosis Probable dehydrogenase 0.0093 0.4401 0.7864
Mycobacterium ulcerans heat shock protein 90 0.0037 0.1534 0.279
Plasmodium falciparum heterochromatin protein 1 0.001 0.0137 0.0121
Entamoeba histolytica deoxycytidyl transferase, putative 0.0062 0.2833 0.744
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0357 0.0395
Echinococcus granulosus GPCR family 2 0.0019 0.0598 0.0598
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0008 0.0034 0.0039
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.052 0.052
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0071 0.0082
Loa Loa (eye worm) hypothetical protein 0.0008 0.0068 0.0079
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Echinococcus multilocularis shaker cognate 0.0008 0.0034 0.0034
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0008 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.1313 0.1515
Toxoplasma gondii heat shock protein 75, putative 0.0026 0.0979 0.1299
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0026 0.0979 0.257
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.052 0.0601
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0694 0.0801
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0071 0.0082
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.2833 0.3135
Loa Loa (eye worm) hypothetical protein 0.001 0.0137 0.0158
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0059 0.2683 0.3097
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0034 0.0034
Plasmodium vivax ataxin-2 like protein, putative 0.0022 0.0747 0.0962
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.184 0.2036
Loa Loa (eye worm) glutathione reductase 0.0041 0.1723 0.1989
Entamoeba histolytica hypothetical protein 0.0008 0.0068 0.0179
Echinococcus multilocularis short transient receptor potential channel 6 0.0008 0.0034 0.0034
Echinococcus granulosus calcium activated potassium channel 0.0008 0.0047 0.0047
Schistosoma mansoni protein phosphatase 2C 0.0008 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0008 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.3809 0.9239
Loa Loa (eye worm) hypothetical protein 0.0008 0.0049 0.0057
Giardia lamblia NADH oxidase lateral transfer candidate 0.0014 0.0357 0.0867
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0008 0.0068 0.0165
Loa Loa (eye worm) hypothetical protein 0.0144 0.7039 0.8125
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.1313 0.1313
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.0333
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Loa Loa (eye worm) hypothetical protein 0.0019 0.0598 0.069
Plasmodium vivax replication factor C subunit 1, putative 0.0008 0.0068 0.0026
Brugia malayi AF-10 protein 0.0008 0.0054 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.1313 0.1515
Loa Loa (eye worm) hypothetical protein 0.0123 0.5932 0.6847
Loa Loa (eye worm) hypothetical protein 0.0008 0.0049 0.0056
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0054 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.1313 0.1515
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0068 0.0165
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0008 0.0034 0.0034
Mycobacterium ulcerans lysophospholipase 0.0062 0.2821 0.513
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0062 0.2833 0.3135
Schistosoma mansoni terminal deoxycytidyl transferase 0.0062 0.2833 0.2833
Echinococcus multilocularis voltage dependent calcium channel 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0068 0.0079
Schistosoma mansoni chromobox protein 0.001 0.0137 0.0137
Brugia malayi hypothetical protein 0.0031 0.1223 0.1412
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.001 0.0137 0.0137
Giardia lamblia Kinase, PLK 0.0081 0.3809 0.9239
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Echinococcus multilocularis lysine specific demethylase 6a 0.0008 0.0049 0.0049
Schistosoma mansoni phd/f-box containing protein 0.0008 0.0049 0.0049
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.1313 0.1515
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0626 0.0693
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0062 0.2833 0.4816
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0425 0.0425
Onchocerca volvulus Huntingtin homolog 0.0144 0.7039 1
Brugia malayi voltage-dependent calcium channel 0.0008 0.0034 0.0039
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Brugia malayi jmjC domain containing protein 0.0008 0.0049 0.0057
Echinococcus multilocularis jumonji domain containing 1A 0.0008 0.0049 0.0049
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0598 0.069
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.06 0.06
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0357 0.1972
Loa Loa (eye worm) heat shock protein 90 0.004 0.1658 0.1914
Brugia malayi Transient-receptor-potential like protein 0.0008 0.0034 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Brugia malayi glucose-6-phosphate dehydrogenase 0.008 0.3755 0.4334
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0008 0.0034 0.0034
Schistosoma mansoni 60S ribosomal protein L21 0.0008 0.0034 0.0034
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0081 0.3809 0.3809
Echinococcus granulosus voltage dependent calcium channel 0.0008 0.0034 0.0034
Trichomonas vaginalis hypothetical protein 0.001 0.0137 0.0333
Trichomonas vaginalis chromobox protein, putative 0.001 0.0137 0.0333
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0008 0.0034 0.0034
Echinococcus multilocularis dna polymerase kappa 0.0062 0.2833 0.2833
Plasmodium vivax heterochromatin protein 1, putative 0.001 0.0137 0.0121
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.1723 0.1907
Brugia malayi hypothetical protein 0.0015 0.0425 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0068 0.0165
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.1313 0.1313
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0037 0.1534 0.2289
Loa Loa (eye worm) hypothetical protein 0.0017 0.052 0.0601
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0068 0.0079
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0071 0.0051
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.001 0.0133 0.0133
Schistosoma mansoni hypothetical protein 0.0031 0.1223 0.1223
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0626 0.0693
Trypanosoma cruzi DNA polymerase eta, putative 0.0123 0.5932 0.6564
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.052 0.0601
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0008 0.0034 0.0037
Toxoplasma gondii ImpB/MucB/SamB family protein 0.008 0.3725 0.5073
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0008 0.0034 0.0039
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0041 0.1718 0.1718
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.1723 0.1989
Loa Loa (eye worm) hypothetical protein 0.0043 0.1842 0.2127
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0068 0.0075
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.1313 0.1313
Trypanosoma brucei Heat shock protein 83, putative 0.004 0.1658 0.1835
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0008 0.0034 0.0037
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.001 0.0133 0.0133
Brugia malayi hypothetical protein 0.0008 0.0034 0.0039
Schistosoma mansoni hypothetical protein 0.001 0.0137 0.0137
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0088 0.4122 1
Echinococcus granulosus replication factor c subunit 1 0.0008 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0082 0.3854 0.3854
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0088 0.4122 0.5619
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0008 0.0049 0.0021
Echinococcus granulosus dna polymerase kappa 0.0062 0.2833 0.2833
Entamoeba histolytica hypothetical protein 0.0031 0.1223 0.3212
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.2448 0.2448
Brugia malayi MH2 domain containing protein 0.0103 0.491 0.5668
Loa Loa (eye worm) hypothetical protein 0.0017 0.052 0.0601
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.001 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0144 0.7039 0.8125
Schistosoma mansoni transient receptor potential channel 4 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.1658 0.1835
Loa Loa (eye worm) hypothetical protein 0.001 0.0152 0.0176
Onchocerca volvulus 0.0026 0.0986 0.136
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0008 0.0034 0.0039
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.008 0.3755 0.3755
Echinococcus granulosus heat shock protein 90 0.004 0.1658 0.1658
Brugia malayi hypothetical protein 0.001 0.0152 0.0176
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0425 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.184 0.2036
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0068 0.0165
Schistosoma mansoni two-pore calcium channel 0.0008 0.0034 0.0034
Schistosoma mansoni chromosome transmission fidelity factor 0.0008 0.0068 0.0068
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0062 0.2821 0.6844
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0008 0.0034 0.0039
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0008 0.0049 0.0049
Onchocerca volvulus 0.0033 0.1313 0.1826
Echinococcus granulosus voltage gated potassium channel 0.0008 0.0034 0.0034
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0008 0.0034 0.0039
Echinococcus granulosus potassium large conductance calcium activated 0.0008 0.0034 0.0034
Toxoplasma gondii Hsp90 domain-containing protein 0.015 0.7309 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Schistosoma mansoni zinc finger protein 0.0015 0.0425 0.0425
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0008 0.0054 0.006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Loa Loa (eye worm) hypothetical protein 0.001 0.0137 0.0158
Trypanosoma cruzi heat shock protein 90, putative 0.0017 0.0481 0.0532
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0425 0.0425
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0034 0.0039
Mycobacterium ulcerans hypothetical protein 0.0021 0.0716 0.1302
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0062 0.2821 0.6844
Echinococcus granulosus lysine specific demethylase 6a 0.0008 0.0049 0.0049
Trypanosoma cruzi PAB1-binding protein , putative 0.0022 0.0747 0.0827
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0062 0.2821 0.6844
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0071 0.0071
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0425 0.0425
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Echinococcus granulosus dna polymerase eta 0.0123 0.5932 0.5932
Schistosoma mansoni DNA polymerase eta 0.0123 0.5932 0.5932
Entamoeba histolytica heat shock protein 90, putative 0.004 0.1658 0.4355
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.1313 0.1313
Brugia malayi ImpB/MucB/SamB family protein 0.0123 0.5932 0.6847
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0034 0.0082
Schistosoma mansoni coup transcription factor 0.0033 0.1313 0.1313
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.1723 0.2656
Entamoeba histolytica hypothetical protein 0.0031 0.1223 0.3212
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0008 0.0049 0.0054
Echinococcus granulosus citrate lyase subunit beta protein 0.0021 0.0716 0.0716
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.1313 0.1313
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0986 0.1139
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0062 0.2821 0.6844
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0068 0.0165
Schistosoma mansoni thyroid hormone receptor 0.0033 0.1313 0.1313
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0694 0.1684
Schistosoma mansoni jumonji domain containing protein 0.0008 0.0049 0.0049
Trichomonas vaginalis chromobox protein, putative 0.006 0.2713 0.6581
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0342 0.0424
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.008 0.3755 0.4155
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0598 0.0598
Brugia malayi topoisomerase 0.0008 0.0068 0.0079
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0425 0.0559
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Schistosoma mansoni nuclear receptor 0.0015 0.0425 0.0425
Schistosoma mansoni heat shock protein 0.004 0.1658 0.1658
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0053 0.2325 0.4228
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0034 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.3809 0.9239
Onchocerca volvulus 0.0008 0.0068 0.0049
Leishmania major DNA polymerase kappa, putative 0.0019 0.0626 0.0693
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0425 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.184 0.2036
Trichomonas vaginalis chromobox protein, putative 0.001 0.0137 0.0333
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.1193 0.1193
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Echinococcus multilocularis chromobox protein 1 0.006 0.2713 0.2713
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0176 0.8663 1
Brugia malayi Hsp90 protein 0.0026 0.0979 0.113
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0008 0.0034 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0034 0.0034
Schistosoma mansoni phosphatidylserine receptor 0.0008 0.0049 0.0049
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.008 0.3755 0.3755
Plasmodium falciparum endoplasmin, putative 0.0029 0.1103 0.1452
Schistosoma mansoni thyroid hormone receptor 0.0033 0.1313 0.1313
Brugia malayi nuclear hormone receptor 0.0015 0.0425 0.0491
Echinococcus multilocularis phd:f box containing protein 0.0008 0.0049 0.0049
Entamoeba histolytica recQ family helicase, putative 0.0011 0.02 0.0525
Onchocerca volvulus 0.001 0.0137 0.0148
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0008 0.0034 0.0034
Leishmania major trypanothione reductase 0.0041 0.1723 0.1907
Schistosoma mansoni chromobox protein 0.006 0.2713 0.2713
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0034 0.0034
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.1313 0.1515
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0425 0.0425
Brugia malayi ecdysteroid receptor 0.0033 0.1313 0.1515
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0088 0.4122 0.561
Schistosoma mansoni heat shock protein 0.004 0.1658 0.1658
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0008 0.0034 0.0034
Giardia lamblia Heat shock protein HSP 90-alpha 0.004 0.1658 0.4023
Trichomonas vaginalis chromobox protein, putative 0.001 0.0137 0.0333
Schistosoma mansoni topbp1 0.0008 0.0068 0.0068
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0014 0.0357 0.065
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0598 0.069
Loa Loa (eye worm) hypothetical protein 0.0009 0.0071 0.0082
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0034 0.0034
Brugia malayi Calcitonin receptor-like protein seb-1 0.0059 0.2683 0.3097
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.06 0.0664
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.1313 0.1515
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0008 0.0034 0.0037
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0103 0.4933 0.8899
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0425 0.0425
Trypanosoma brucei PAB1-binding protein , putative 0.0022 0.0747 0.0827
Plasmodium falciparum heat shock protein 90, putative 0.0023 0.081 0.1049
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.036
Giardia lamblia Grp94/Hsp90 0.0037 0.1534 0.3722
Echinococcus granulosus JmjC domain containing protein 4 0.0008 0.0049 0.0049
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.06 0.06
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.2448 0.2826
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.001 0.0137 0.0142
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.1723 0.1723
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0054 0.0054
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.001 0.0137 0.0137
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0021 0.0716 0.1302
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0093 0.4401 0.7864
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0357 0.0395
Schistosoma mansoni hypothetical protein 0.0019 0.0598 0.0598
Brugia malayi hypothetical protein 0.0008 0.0068 0.0079
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0034 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.1313 0.1515
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Trypanosoma brucei unspecified product 0.0043 0.184 0.2036
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0081 0.3809 0.4214
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0008 0.0034 0.0034
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0093 0.4401 0.7864
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Toxoplasma gondii heat shock protein 90, putative 0.004 0.1658 0.2233
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0071 0.0082
Echinococcus granulosus phd:f box containing protein 0.0008 0.0049 0.0049
Trypanosoma brucei unspecified product 0.0062 0.2833 0.3135
Schistosoma mansoni DNA polymerase IV / kappa 0.0019 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0019 0.0626 0.0723
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Brugia malayi nuclear receptor RXR 0.0017 0.052 0.0601
Echinococcus granulosus transient receptor potential gamma protein 0.0008 0.0034 0.0034
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0357 0.0395
Mycobacterium ulcerans lipoprotein LpqF 0.0055 0.2449 0.4453
Echinococcus granulosus PHD finger protein rhinoceros 0.0025 0.0922 0.0922
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0034 0.0034
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0626 0.0815
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0626 0.0693
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0425 0.0425
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0034 0.0034
Schistosoma mansoni transient receptor potential channel 0.0008 0.0049 0.0049
Trichomonas vaginalis replication factor C large subunit, putative 0.0008 0.0068 0.0165
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0008 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0093 0.4401 0.7864
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Echinococcus multilocularis sodium channel protein 0.0008 0.0034 0.0034
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0088 0.4122 0.561
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0068 0.0075
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0021 0.0716 0.1302
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0694 0.0694
Schistosoma mansoni voltage-dependent calcium channel 0.0008 0.0034 0.0034
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0008 0.0068 0.0075
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Leishmania major heat shock protein, putative 0.0026 0.0979 0.1083
Echinococcus multilocularis Chromo domain 0.001 0.0137 0.0137
Schistosoma mansoni hypothetical protein 0.0008 0.0034 0.0034
Echinococcus granulosus two pore calcium channel protein 2 0.0008 0.0034 0.0034
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.052 0.0601
Schistosoma mansoni vesicular amine transporter 0.0008 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0034 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.0333
Loa Loa (eye worm) ryanodine receptor 0.0008 0.0034 0.0039
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Brugia malayi Valyl-tRNA synthetase 0.001 0.0137 0.0158
Entamoeba histolytica hypothetical protein 0.0031 0.1223 0.3212
Trypanosoma cruzi Heat shock protein 83, putative 0.004 0.1658 0.1835
Loa Loa (eye worm) hypothetical protein 0.0041 0.1718 0.1983
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0021 0.0716 0.0792
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.06 0.06
Mycobacterium tuberculosis Conserved hypothetical protein 0.0062 0.2833 0.4816
Echinococcus granulosus shaker cognate 0.0008 0.0034 0.0034
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0008 0.0034 0.0034
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0626 0.0693
Loa Loa (eye worm) voltage-gated calcium channel 0.0008 0.0034 0.0039
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0008 0.0049 0.0054
Loa Loa (eye worm) hypothetical protein 0.0176 0.8663 1
Trypanosoma brucei chrX additional, unordered contigs 0.0019 0.0626 0.0693
Brugia malayi SET domain containing protein 0.001 0.0137 0.0158
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0357 0.0445
Echinococcus granulosus bloom syndrome protein 0.0021 0.0694 0.0694
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0034 0.0034
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0026 0.0959 0.1062
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.1313 0.1515
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.008 0.3755 1
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.2833 0.3271
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0062 0.2833 0.3271
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0425 0.0425
Trypanosoma brucei heat shock protein 90, putative 0.004 0.1658 0.1835
Leishmania major hypothetical protein, conserved 0.0008 0.0049 0.0054
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0008 0.0034 0.0034
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0062 0.2833 0.2833
Plasmodium falciparum phd finger protein, putative 0.0025 0.0922 0.1202
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0425 0.0491
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.2448 0.2448
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.06 0.0758
Echinococcus granulosus voltage dependent calcium channel 0.0008 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.2821 0.6844
Entamoeba histolytica heat shock protein 90, putative 0.004 0.1658 0.4355
Echinococcus granulosus muscleblind protein 0.0176 0.8663 0.8663
Trypanosoma brucei polo-like protein kinase 0.0081 0.3809 0.4214
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0008 0.0049 0.0021
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0425 0.0491
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.1313 0.1515
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0062 0.2821 0.5719
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0008 0.0068 0.0165
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0357 0.0867
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.06 0.06
Trypanosoma brucei DNA polymerase eta, putative 0.0123 0.5932 0.6564
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Echinococcus granulosus voltage gated hydrogen channel 1 0.0008 0.0034 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.2448 0.2448
Onchocerca volvulus Huntingtin homolog 0.0144 0.7039 1
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0008 0.0034 0.0034
Brugia malayi cation channel family protein 0.0008 0.0034 0.0039
Schistosoma mansoni calcium-activated potassium channel 0.0008 0.0034 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0357 0.0425
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0357 0.0445
Echinococcus granulosus jumonji domain containing 1A 0.0008 0.0049 0.0049
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.1658 0.1835
Schistosoma mansoni DNA helicase recq1 0.0009 0.0071 0.0071
Entamoeba histolytica hypothetical protein 0.001 0.0137 0.036
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0008 0.0034 0.0034
Trypanosoma cruzi monoglyceride lipase, putative 0.0062 0.2821 0.3122
Schistosoma mansoni hypothetical protein 0.0202 1 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0034 0.0034
Echinococcus granulosus jumonji domain containing protein 0.0035 0.1426 0.1426
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0062 0.2821 0.7407
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.1313 0.1515
Trypanosoma brucei monoglyceride lipase, putative 0.0062 0.2821 0.3122
Brugia malayi ecdysone receptor 0.0015 0.0425 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Plasmodium vivax heat shock protein, putative 0.015 0.7309 1
Echinococcus multilocularis sodium leak channel non selective protein 0.0008 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.1313 0.1515
Leishmania major hypothetical protein, conserved 0.0008 0.0034 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0183 0.9037 1
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0114 0.5499 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Entamoeba histolytica hypothetical protein 0.001 0.0137 0.036
Echinococcus multilocularis muscleblind protein 1 0.0176 0.8663 0.8663
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0357 0.0357
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.001 0.0137 0.0121
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.1313 0.1826
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.1313 0.1515
Loa Loa (eye worm) hypothetical protein 0.0008 0.0068 0.0079
Echinococcus multilocularis heat shock protein 90 0.004 0.1658 0.1658
Schistosoma mansoni hypothetical protein 0.0019 0.0598 0.0598
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0357 0.0425
Trypanosoma cruzi FHA domain containing protein, putative 0.0008 0.0068 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0425 0.0425
Loa Loa (eye worm) heterochromatin protein 1 0.006 0.2713 0.3131
Echinococcus granulosus chromobox protein 1 0.006 0.2713 0.2713
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0165 0.0191
Brugia malayi PHD-finger family protein 0.0025 0.0922 0.1064
Brugia malayi Thioredoxin reductase 0.0041 0.1723 0.1989
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0425 0.0491
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0008 0.0034 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.2833 0.3135
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Echinococcus multilocularis voltage gated potassium channel 0.0008 0.0034 0.0034
Echinococcus granulosus peregrin 0.0025 0.0922 0.0922
Schistosoma mansoni endoplasmin 0.004 0.1658 0.1658
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.1313 0.1313
Brugia malayi Heterochromatin protein 1 0.006 0.2713 0.3131
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0008 0.0054 0.006
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0008 0.0054 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0855 0.2075
Echinococcus multilocularis transfer RNA-Gly 0.0008 0.0034 0.0034
Brugia malayi nuclear hormone receptor 0.0033 0.1313 0.1515
Toxoplasma gondii PHD-finger domain-containing protein 0.0008 0.0054 0.0028
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0425 0.0425
Plasmodium falciparum heat shock protein 90, putative 0.015 0.7309 1
Loa Loa (eye worm) RecQ helicase 0.0021 0.0694 0.0801
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0059 0.2683 0.3097
Loa Loa (eye worm) hypothetical protein 0.0008 0.0068 0.0079
Echinococcus multilocularis calcium activated potassium channel 0.0008 0.0047 0.0047
Trichomonas vaginalis endoplasmin, putative 0.0029 0.1103 0.2676
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.1313 0.1313
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Brugia malayi chromobox protein homolog 3 0.0034 0.1359 0.1569
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.06 0.0664
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0357 0.0425
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0037 0.1534 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.2448 0.2448
Mycobacterium tuberculosis Possible lysophospholipase 0.0062 0.2821 0.4791
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0747 0.0962
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.036
Schistosoma mansoni endoplasmin 0.004 0.1658 0.1658
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.008 0.3755 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.1313 0.1313
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0034 0.0034
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0008 0.0034 0.0034
Echinococcus multilocularis transient receptor potential gamma protein 0.0008 0.0034 0.0034
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.1366 0.1511
Echinococcus multilocularis PHD finger protein rhinoceros 0.0025 0.0922 0.0922
Mycobacterium ulcerans hypothetical protein 0.0019 0.0626 0.1139
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0008 0.0034 0.0034
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0088 0.4122 1
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0062 0.2821 0.7407
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0062 0.2821 0.6844
Brugia malayi hypothetical protein 0.0022 0.0747 0.0863
Echinococcus multilocularis heat shock protein 0.004 0.1658 0.1658
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0093 0.4401 0.7864
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.1313 0.1515
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.3809 0.3809
Toxoplasma gondii PHD-finger domain-containing protein 0.0025 0.0922 0.1221
Brugia malayi Muscleblind-like protein 0.0176 0.8663 1
Echinococcus multilocularis nibrin 0.0008 0.0068 0.0068
Treponema pallidum NADH oxidase 0.0014 0.0357 0.0952
Plasmodium falciparum thioredoxin reductase 0.0014 0.0357 0.0425
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0008 0.0049 0.0054
Loa Loa (eye worm) hypothetical protein 0.001 0.0137 0.0158
Loa Loa (eye worm) hypothetical protein 0.0104 0.4974 0.5742
Loa Loa (eye worm) hypothetical protein 0.0033 0.1313 0.1515
Onchocerca volvulus 0.001 0.0137 0.0148
Schistosoma mansoni hypothetical protein 0.0202 1 1
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0008 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.2821 0.6844
Trypanosoma cruzi polo-like protein kinase, putative 0.0081 0.3809 0.4214
Treponema pallidum DNA ligase (lig) 0.0008 0.0068 0.0182
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.008 0.3755 0.4155
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.06 0.0758
Plasmodium falciparum replication factor C subunit 1, putative 0.0008 0.0068 0.0026
Toxoplasma gondii ATPase, AAA family protein 0.0008 0.0068 0.0047
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.052 0.052
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0351 0.0415
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0034 0.0034
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0626 0.0693
Echinococcus granulosus chromobox protein 1 0.006 0.2713 0.2713
Schistosoma mansoni hypothetical protein 0.0025 0.0922 0.0922
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.1193 0.1377
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.001 0.0137 0.0142
Loa Loa (eye worm) jmjC domain-containing protein 0.0008 0.0049 0.0057
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0034 0.0034
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0747 0.0962
Leishmania major hypothetical protein, unknown function 0.0008 0.0034 0.0037
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0093 0.4401 0.8921
Trypanosoma brucei trypanothione reductase 0.0041 0.1723 0.1907
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0055 0.2449 0.4964
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.06 0.06
Brugia malayi Type III restriction enzyme, res subunit family protein 0.001 0.0137 0.0158
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.06 0.0664
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0034 0.0034
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0034 0.0034
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0008 0.0034 0.0039
Plasmodium falciparum lysophospholipase, putative 0.0062 0.2821 0.3818
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0034 0.0039
Brugia malayi nuclear receptor NHR-88 0.0033 0.1313 0.1515
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.1313 0.1313
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0008 0.0034 0.0034
Brugia malayi isocitrate dehydrogenase 0.0019 0.06 0.0692
Brugia malayi CHD4 protein 0.001 0.0137 0.0158
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0357 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.1313 0.1313
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.02 0.0485
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.1313 0.1313
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0357 0.0395
Trichomonas vaginalis heat shock protein, putative 0.0037 0.1534 0.3722
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0008 0.0034 0.0034
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0008 0.0034 0.0034
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0626 0.0815
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0008 0.0034 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0008 0.0049 0.0049
Entamoeba histolytica hypothetical protein 0.001 0.0137 0.036
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.06 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Onchocerca volvulus 0.0015 0.0425 0.0559
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0598 0.069
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.052 0.0601
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.001 0.0137 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.3809 0.9239
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0034 0.1366 0.1366
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0026 0.0979 0.1349
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0071 0.0071
Plasmodium falciparum glutathione reductase 0.0014 0.0357 0.0425
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Loa Loa (eye worm) helicase 0.001 0.0137 0.0158
Schistosoma mansoni hypothetical protein 0.0008 0.0054 0.0054
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0357 0.0395
Toxoplasma gondii heat shock protein HSP90 0.004 0.1658 0.2233
Brugia malayi jmjC domain containing protein 0.0008 0.0049 0.0057
Brugia malayi Endoplasmin precursor 0.004 0.1658 0.1914
Trichomonas vaginalis CAMK family protein kinase 0.004 0.17 0.4124
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0034 0.0034
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.1313 0.1313
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0694 0.1684
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0071 0.003
Brugia malayi cation channel family protein 0.0008 0.0034 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0137 0.0333
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0008 0.0068 0.0165
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0008 0.0034 0.0037
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0425 0.0491
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0034 0.0034
Brugia malayi tailless protein 0.0015 0.0425 0.0491
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Leishmania major DNA damage repair protein, putative 0.0019 0.0626 0.0693
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.001 0.0137 0.0137
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0034 0.0034
Echinococcus granulosus sodium channel protein 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Schistosoma mansoni topbp1 0.0008 0.0068 0.0068
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.1718 0.1983
Loa Loa (eye worm) hypothetical protein 0.0034 0.1359 0.1569
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.1313 0.1313
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0008 0.0034 0.0034
Plasmodium vivax DNA repair protein REV1, putative 0.0019 0.0626 0.0795
Plasmodium vivax hypothetical protein, conserved 0.001 0.0137 0.0121
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0626 0.0693
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.0333
Treponema pallidum heat shock protein 90 0.0037 0.1534 0.4085
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0034 0.0034
Echinococcus granulosus ryanodine receptor 44f 0.0008 0.0034 0.0034
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0357 0.0395
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0008 0.0068 0.0047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0357 0.0395
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.1313 0.1313
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.06 0.0778
Giardia lamblia Replication factor C, subunit 1 0.0008 0.0068 0.0165
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0008 0.0068 0.0075
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0071 0.0172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.1313 0.1515
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0598 0.0598
Plasmodium vivax heat shock protein 86, putative 0.004 0.1658 0.2217
Loa Loa (eye worm) calcium channel 0.0008 0.0034 0.0039
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.1313 0.1826
Schistosoma mansoni voltage-gated cation channel 0.0008 0.0034 0.0034
Brugia malayi DKFZp564C0469 protein 0.0008 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0008 0.0049 0.0057
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.008 0.3755 0.4334
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0598 0.0598
Schistosoma mansoni transient receptor potential channel 0.0008 0.0034 0.0034
Entamoeba histolytica serine/threonine protein kinase, putative 0.0081 0.3809 1
Trichomonas vaginalis heat shock protein, putative 0.0029 0.1103 0.2676
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.1723 0.2306
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0034 0.0034
Brugia malayi jmjC domain containing protein 0.0008 0.0049 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0183 0.9037 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.001 0.0137 0.0137
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.2448 0.2448
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0088 0.4122 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0425 0.0491
Loa Loa (eye worm) transcription factor SMAD2 0.0103 0.491 0.5668
Onchocerca volvulus Serine\/threonine kinase homolog 0.0081 0.3809 0.5389
Loa Loa (eye worm) hypothetical protein 0.0008 0.0054 0.0063
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Brugia malayi jmjC domain containing protein 0.0008 0.0049 0.0057
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0425 0.0491
Loa Loa (eye worm) endoplasmin 0.004 0.1658 0.1914
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.06 0.06
Brugia malayi hypothetical protein 0.0017 0.052 0.0601
Brugia malayi Isocitrate dehydrogenase 0.0019 0.06 0.0692
Trichomonas vaginalis CAMK family protein kinase 0.0081 0.3809 0.9239
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.1313 0.1313
Echinococcus multilocularis heat shock protein 90 0.0034 0.1366 0.1366
Echinococcus granulosus short transient receptor potential channel 6 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.001 0.0137 0.0158
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0071 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.0333
Schistosoma mansoni heat shock protein 0.0026 0.0979 0.0979
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.1313 0.1515
Brugia malayi nuclear receptor NHR-67 0.0015 0.0425 0.0491
Mycobacterium ulcerans hypothetical protein 0.0062 0.2821 0.513
Toxoplasma gondii PHD-finger domain-containing protein 0.0025 0.0922 0.1221
Brugia malayi ion channel NompC 0.0008 0.0034 0.0039
Trypanosoma cruzi DNA polymerase eta, putative 0.008 0.3725 0.4122
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0008 0.0034 0.0039
Schistosoma mansoni chromobox protein 0.001 0.0137 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0037 0.1534 0.1698
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.1658 0.1835
Echinococcus granulosus endoplasmin 0.0037 0.1534 0.1534
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.2833 0.6874
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.0137 0.036
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0021 0.0716 0.0792
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.1359 0.3298
Giardia lamblia DNA damage repair protein 0.0019 0.0626 0.1519
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0037 0.1534 0.311
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Brugia malayi Protein cec-1. 0.001 0.0137 0.0158
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0049 0.0049
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0062 0.2833 0.2833
Plasmodium vivax PST-A protein 0.0062 0.2821 0.3818
Trichomonas vaginalis heat shock protein, putative 0.0023 0.081 0.1966
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0028 0.1063 0.1372
Leishmania major DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.1313 0.1515
Trypanosoma brucei hypothetical protein, conserved 0.0183 0.9037 1
Trichomonas vaginalis chromobox protein, putative 0.0036 0.149 0.3616
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0034 0.1359 0.1892
Trypanosoma cruzi polo-like protein kinase, putative 0.0081 0.3809 0.4214
Onchocerca volvulus Alhambra homolog 0.0025 0.0922 0.1268
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0103 0.4933 1
Plasmodium falciparum esterase, putative 0.0062 0.2821 0.3818
Trypanosoma brucei heat shock protein 90, putative 0.004 0.1658 0.1835
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0034 0.0034
Schistosoma mansoni kinase 0.0041 0.1755 0.1755
Schistosoma mansoni voltage-gated ion channel 0.0008 0.0034 0.0034
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0425 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Trichomonas vaginalis CAMK family protein kinase 0.004 0.17 0.4124
Loa Loa (eye worm) DR-78 0.0015 0.0425 0.0491
Echinococcus multilocularis dna polymerase eta 0.0123 0.5932 0.5932
Plasmodium falciparum lysophospholipase, putative 0.0062 0.2821 0.3818
Echinococcus granulosus Chromobox protein 3 0.001 0.0137 0.0137
Echinococcus multilocularis short transient receptor potential channel 6 0.0008 0.0049 0.0049
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.2833 0.5152
Brugia malayi olfactory channel protein osm-9 0.0008 0.0049 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.1313 0.1313
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0034 0.0034
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.06 0.0778
Echinococcus multilocularis chromobox protein 2 0.001 0.0137 0.0137
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.1313 0.1313
Trypanosoma brucei heat shock protein 84, putative 0.0026 0.0979 0.1083
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0014 0.0357 0.065
Echinococcus granulosus hypothetical protein 0.0008 0.0034 0.0034
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.1313 0.1313
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0036 0.149 0.208
Brugia malayi Bromodomain containing protein 0.0025 0.0922 0.1064
Brugia malayi jmjC domain containing protein 0.0082 0.3854 0.4449
Giardia lamblia DINP protein human, muc B family 0.0062 0.2833 0.6874
Echinococcus multilocularis voltage dependent calcium channel 0.0008 0.0034 0.0034
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0008 0.0034 0.0039
Loa Loa (eye worm) voltage-gated potassium channel 0.0008 0.0034 0.0039
Echinococcus granulosus lysine specific demethylase 5A 0.003 0.1193 0.1193
Loa Loa (eye worm) hypothetical protein 0.001 0.0137 0.0158
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0021 0.0716 0.0792
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0008 0.0034 0.0034
Plasmodium falciparum DNA repair protein REV1, putative 0.0019 0.0626 0.0795
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.2448 0.2448
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0137 0.0333
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0008 0.0034 0.0039
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0039
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0055 0.2449 0.4068
Plasmodium falciparum thioredoxin reductase 0.0041 0.1723 0.2306
Loa Loa (eye worm) hypothetical protein 0.0015 0.0425 0.0491
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0021 0.0716 0.0697
Schistosoma mansoni hypothetical protein 0.0019 0.0598 0.0598
Trypanosoma brucei heat shock protein, putative 0.004 0.1658 0.1835
Loa Loa (eye worm) heat shock protein 75 0.0026 0.0979 0.113
Loa Loa (eye worm) MH2 domain-containing protein 0.0103 0.491 0.5668
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0034 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0036 0.149 0.3616
Mycobacterium tuberculosis Probable reductase 0.0093 0.4401 0.7864
Echinococcus granulosus nibrin 0.0008 0.0068 0.0068
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0081 0.3809 0.4396
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0008 0.0034 0.0039
Schistosoma mansoni DNA ligase IV 0.0008 0.0068 0.0068
Echinococcus multilocularis endoplasmin 0.0037 0.1534 0.1534
Echinococcus multilocularis chromobox protein 1 0.006 0.2713 0.2713
Brugia malayi nuclear receptor NHR-88 0.0015 0.0425 0.0491
Leishmania major heat shock protein 83-1 0.004 0.1658 0.1835
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0357 0.0395
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.2833 0.3135
Echinococcus granulosus two pore calcium channel protein 1 0.0008 0.0034 0.0034
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.1313 0.1313
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.052 0.052
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0008 0.0068 0.0079
Echinococcus multilocularis ryanodine receptor 44f 0.0008 0.0034 0.0034
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0626 0.0693
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0357 0.0412
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0021 0.0716 0.1302
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0034 0.0034
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0922 0.1202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.1313 0.1515
Onchocerca volvulus 0.0015 0.0425 0.0559
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0049 0.0049
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.1658 0.1835
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0034 0.0034
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0031 0.1223 0.1223
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0357 0.0395
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0357 0.0357
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0034 0.0034
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.1193 0.1193
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0425 0.0425

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 270 nM Antagonist activity at rat TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-induced calcium flux ChEMBL. 21531136
IC50 (functional) = 520 nM Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-induced calcium flux ChEMBL. 21531136

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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