Detailed information for compound 1556307

Basic information

Technical information
  • TDR Targets ID: 1556307
  • Name: 1-(3,6,7-trimethyl-4-oxido-1-oxoquinoxalin-1- ium-2-yl)ethanone
  • MW: 246.262 | Formula: C13H14N2O3
  • H donors: 0 H acceptors: 3 LogP: 0.37 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc2[n+]([O-])c(C(=O)C)c([n+](c2cc1C)[O-])C
  • InChi: 1S/C13H14N2O3/c1-7-5-11-12(6-8(7)2)15(18)13(10(4)16)9(3)14(11)17/h5-6H,1-4H3
  • InChiKey: GPLMTFAZFDEAQA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(3,6,7-trimethyl-4-oxido-1-oxo-quinoxalin-1-ium-2-yl)ethanone
  • 1-(3,6,7-trimethyl-4-oxido-1-oxo-2-quinoxalin-1-iumyl)ethanone
  • 1-(1-keto-3,6,7-trimethyl-4-oxido-quinoxalin-1-ium-2-yl)ethanone
  • AIDS099125
  • Ethanone, 1-(3,6,7-trimethyl-1,4-dioxido-2-quinoxalinyl)-
  • NSC621484
  • NCI60_006295
  • AIDS-099125

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.0673 0.57
Echinococcus multilocularis musashi 0.0033 0.0287 0.0287
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0374 0.2536
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0022
Echinococcus granulosus acetylcholinesterase 0.0072 0.0805 0.0805
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.1101 1
Brugia malayi intermediate filament protein 0.0033 0.0287 0.0338
Schistosoma mansoni smad1 5 8 and 0.0033 0.029 0.029
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0074 0.0077
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0106 0.0805
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0533 0.6864 0.8077
Schistosoma mansoni tar DNA-binding protein 0.0657 0.8497 0.8497
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0106 0.1331
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0125 0.0147
Schistosoma mansoni Smad4 0.0033 0.029 0.029
Brugia malayi Cathepsin L-like cysteine proteinase 0.0014 0.0037 0.0044
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0052 0.0052
Brugia malayi Pre-SET motif family protein 0.0032 0.0275 0.0324
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0106 0.1331
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0074 0.0074
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0074 0.0077
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0162 0.0162
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0169 0.2075 0.2075
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0374 0.2593
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Brugia malayi Bromodomain containing protein 0.0039 0.0374 0.044
Onchocerca volvulus 0.002 0.0125 0.0395
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0106 0.1331
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0077
Brugia malayi Carboxylesterase family protein 0.0072 0.0805 0.0947
Onchocerca volvulus 0.0014 0.0037 0.0117
Loa Loa (eye worm) acetylcholinesterase 1 0.0072 0.0805 0.0947
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0066 0.0066
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0106 0.0805
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0125 0.0337
Loa Loa (eye worm) hypothetical protein 0.0039 0.0375 0.0442
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0125 0.0125
Brugia malayi MH2 domain containing protein 0.0033 0.029 0.0342
Loa Loa (eye worm) hypothetical protein 0.0015 0.0058 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Toxoplasma gondii hypothetical protein 0.0033 0.0287 0.1797
Onchocerca volvulus 0.002 0.0125 0.0395
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0088 0.0088
Brugia malayi Cathepsin L-like precursor 0.0014 0.0037 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Onchocerca volvulus 0.0251 0.3164 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0074 0.0074
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0374 0.0374
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Loa Loa (eye worm) carboxylesterase 0.0072 0.0805 0.0947
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0342 0.0342
Schistosoma mansoni lamin 0.0033 0.0287 0.0287
Loa Loa (eye worm) TAR-binding protein 0.0657 0.8497 1
Brugia malayi MH2 domain containing protein 0.0033 0.029 0.0342
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0169 0.2075 0.2442
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0022
Onchocerca volvulus 0.002 0.0125 0.0395
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0012 0.0019 0.0019
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0228 0.0268
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0106 0.0805
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0106 0.0805
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0125 0.2606
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.1101 1
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0228 0.1368
Leishmania major hypothetical protein, conserved 0.0106 0.1258 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0106 0.0805
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0662 0.0662
Brugia malayi isocitrate dehydrogenase 0.0016 0.0074 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0657 0.8497 0.8497
Brugia malayi RNA binding protein 0.0657 0.8497 1
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0106 0.0805
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0872 0.6765
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0037 0.0058
Loa Loa (eye worm) hypothetical protein 0.0072 0.0805 0.0947
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0106 0.1331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0052 0.0052
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0169 0.2075 0.2075
Loa Loa (eye worm) nuclear factor I 0.0018 0.0098 0.0115
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0287 0.1797
Schistosoma mansoni neuroligin 3 (S09 family) 0.0012 0.0019 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Echinococcus granulosus lamin 0.0033 0.0287 0.0287
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0784 0.6028
Echinococcus granulosus tar DNA binding protein 0.0657 0.8497 0.8497
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0074 0.0074
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0662 0.0662
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0125 0.0429
Echinococcus granulosus neuropeptide receptor A26 0.0491 0.631 0.631
Echinococcus granulosus neuroligin 0.0012 0.0019 0.0019
Brugia malayi Smad1 0.0033 0.029 0.0342
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0106 0.1331
Onchocerca volvulus 0.0012 0.0019 0.0059
Echinococcus multilocularis BC026374 protein (S09 family) 0.0012 0.0019 0.0019
Schistosoma mansoni microtubule-associated protein tau 0.0771 1 1
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0012 0.0019 0.0019
Brugia malayi Carboxylesterase family protein 0.0072 0.0805 0.0947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Leishmania major cathepsin L-like protease 0.0077 0.0872 0.6765
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0474 0.0558
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0228 0.0268
Schistosoma mansoni smad1 5 8 and 0.0033 0.029 0.029
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.029 0.0342
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0505 0.0505
Schistosoma mansoni smad1 5 8 and 0.0033 0.029 0.029
Schistosoma mansoni lamin 0.0033 0.0287 0.0287
Schistosoma mansoni smad 0.0033 0.029 0.029
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0106 0.0344
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0474 0.0474
Brugia malayi MH2 domain containing protein 0.0482 0.6191 0.7286
Brugia malayi RNA recognition motif domain containing protein 0.0657 0.8497 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0044
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.029 0.029
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0106 0.0106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0474 0.0474
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0106 0.0805
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0074 0.0845
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0106 0.0805
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.1258 1
Brugia malayi Cytochrome P450 family protein 0.0059 0.0638 0.0751
Brugia malayi hypothetical protein 0.0182 0.2259 0.2658
Echinococcus granulosus lamin dm0 0.0033 0.0287 0.0287
Brugia malayi TAR-binding protein 0.0657 0.8497 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0433 0.0509
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.029 0.029
Leishmania major cysteine peptidase A (CPA) 0.002 0.0125 0.0503
Loa Loa (eye worm) hypothetical protein 0.0106 0.1258 0.1481
Brugia malayi Inositol-1 0.0039 0.0374 0.044
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0088 0.0104
Echinococcus multilocularis GPCR, family 2 0.0169 0.2075 0.2075
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.029 0.029
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0019 0.0019
Onchocerca volvulus 0.0033 0.0287 0.0908
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0374 0.113
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0228 0.0268
Brugia malayi MH1 domain containing protein 0.0018 0.0098 0.0115
Schistosoma mansoni tar DNA-binding protein 0.0657 0.8497 0.8497
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.1101 0.8672
Loa Loa (eye worm) inositol-1 0.0039 0.0374 0.044
Brugia malayi Cathepsin L-like precursor 0.0014 0.0037 0.0044
Brugia malayi Cathepsin L-like precursor 0.002 0.0125 0.0147
Schistosoma mansoni BC026374 protein (S09 family) 0.0012 0.0019 0.0019
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.0673 1
Entamoeba histolytica cysteine protease, putative 0.002 0.0125 0.2606
Brugia malayi Muscleblind-like protein 0.018 0.2231 0.2626
Brugia malayi Carboxylesterase family protein 0.0012 0.0019 0.0022
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0074 0.0077
Toxoplasma gondii cathepsin CPL 0.002 0.0125 0.0429
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0022
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0106 0.1331
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0474 0.0474
Echinococcus multilocularis lamin dm0 0.0033 0.0287 0.0287
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0074 0.0074
Leishmania major cathepsin L-like protease 0.002 0.0125 0.0503
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0097 0.0114
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0106 0.1331
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Brugia malayi Cathepsin L-like precursor 0.002 0.0125 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Schistosoma mansoni Smad4 0.0015 0.0052 0.0052
Brugia malayi MH1 domain containing protein 0.0018 0.0098 0.0115
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0074 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.0673 0.0673
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0052 0.0052
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.0673 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.1101 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0169 0.2075 0.2442
Loa Loa (eye worm) hypothetical protein 0.018 0.2231 0.2626
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0106 0.1331
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0106 0.1331
Brugia malayi Latrophilin receptor protein 2 0.0169 0.2075 0.2442
Loa Loa (eye worm) transcription factor SMAD2 0.0482 0.6191 0.7286
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0505 0.0505
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0106 0.0805
Echinococcus multilocularis carboxylesterase 5A 0.0072 0.0805 0.0805
Loa Loa (eye worm) hypothetical protein 0.0018 0.0098 0.0115
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0019 0.0019
Echinococcus granulosus acetylcholinesterase 0.0072 0.0805 0.0805
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Onchocerca volvulus 0.0032 0.0275 0.0871
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0275 0.0275
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0287 0.0338
Schistosoma mansoni smad 0.0015 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0374 0.2593
Brugia malayi N-terminal motif family protein 0.0175 0.2156 0.2537
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0275 0.0275
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0275 0.1701
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0106 0.0805
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0074 0.0077
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0872 0.6765
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0169 0.2075 0.2075
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0638 0.0751
Echinococcus multilocularis muscleblind protein 0.018 0.2231 0.2231
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.1101 0.5
Schistosoma mansoni inositol monophosphatase 0.0039 0.0374 0.0374
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.0673 0.0673
Schistosoma mansoni hypothetical protein 0.0364 0.4647 0.4647
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Loa Loa (eye worm) MH2 domain-containing protein 0.0482 0.6191 0.7286
Echinococcus multilocularis cysteine protease 0.002 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0048 0.0487 0.0487
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.1101 0.8672
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0533 0.6864 0.8077
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0072 0.0805 0.0805
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0374 0.3285
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0474 0.0474
Brugia malayi Cytochrome P450 family protein 0.0019 0.0106 0.0125
Loa Loa (eye worm) cysteine protease 0.002 0.0125 0.0147
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0066 0.0066
Echinococcus granulosus intermediate filament protein 0.0033 0.0287 0.0287
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.1258 1
Echinococcus granulosus GPCR family 2 0.0169 0.2075 0.2075
Brugia malayi Carboxylesterase family protein 0.0012 0.0019 0.0022
Brugia malayi Pre-SET motif family protein 0.0221 0.2763 0.3251
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0106 0.0269
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0106 0.1331
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0872 0.6765
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.1258 1
Echinococcus multilocularis zinc finger protein 0.002 0.0122 0.0122
Onchocerca volvulus 0.002 0.0125 0.0395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0106 0.0805
Onchocerca volvulus 0.002 0.0125 0.0395
Echinococcus multilocularis Smad4 0.0033 0.029 0.029
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.1101 0.5
Loa Loa (eye worm) Smad1 0.0033 0.029 0.0342
Loa Loa (eye worm) hypothetical protein 0.0533 0.6864 0.8077
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0088 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0106 0.1331
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0505 0.0505
Echinococcus granulosus para nitrobenzyl esterase 0.0012 0.0019 0.0019
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0015 0.0052 0.0164
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.1101 0.1101
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0022
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0125 0.0429
Loa Loa (eye worm) hypothetical protein 0.0094 0.1101 0.1296
Echinococcus multilocularis 0.0019 0.0106 0.0106
Onchocerca volvulus Cathepsin L homolog 0.002 0.0125 0.0395
Onchocerca volvulus 0.0182 0.2259 0.7139
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.1258 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0505 0.0505
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0106 0.0344
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0374 1
Brugia malayi Probable ClpP-like protease 0.0094 0.1101 0.1296
Echinococcus granulosus zinc finger protein 0.002 0.0122 0.0122
Schistosoma mansoni zinc finger protein 0.002 0.0122 0.0122
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0228 0.1368
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0088 0.0104
Echinococcus granulosus cathepsin l1 0.0014 0.0037 0.0037
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0106 0.0805
Schistosoma mansoni zinc finger protein 0.0016 0.0065 0.0065
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.029 0.0342
Leishmania major cathepsin L-like protease 0.002 0.0125 0.0503
Brugia malayi Cytochrome P450 family protein 0.0028 0.0228 0.0268
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0106 0.0344
Loa Loa (eye worm) fibroinase 0.002 0.0125 0.0147
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0137 0.0161
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0106 0.0805
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0125 0.0125
Brugia malayi hypothetical protein 0.0012 0.0019 0.0022
Brugia malayi hypothetical protein 0.0069 0.0762 0.0897
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.026 0.026
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0106 0.0344
Echinococcus multilocularis acetylcholinesterase 0.0072 0.0805 0.0805
Loa Loa (eye worm) cytochrome P450 0.0019 0.0106 0.0125
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0106 0.0805
Echinococcus multilocularis tar DNA binding protein 0.0657 0.8497 0.8497
Loa Loa (eye worm) hypothetical protein 0.0169 0.2075 0.2442
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0374 0.0374
Brugia malayi Bromodomain containing protein 0.0077 0.0868 0.1022
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0106 0.0344
Loa Loa (eye worm) hypothetical protein 0.0033 0.0287 0.0338
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0228 0.1368
Brugia malayi Cathepsin L-like precursor 0.002 0.0125 0.0147
Onchocerca volvulus Cathepsin F homolog 0.002 0.0125 0.0395
Loa Loa (eye worm) hypothetical protein 0.018 0.2231 0.2626
Echinococcus multilocularis neuropeptide receptor A26 0.0491 0.631 0.631
Brugia malayi cathepsin L-like precursor 0.0014 0.0037 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0106 0.1331
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0106 0.1331
Schistosoma mansoni Smad4 0.0015 0.0052 0.0052
Schistosoma mansoni gliotactin 0.0012 0.0019 0.0019
Brugia malayi Carboxylesterase family protein 0.0012 0.0019 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0125 0.0503
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0125 0.0147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0474 0.0474
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0655 0.4948
Echinococcus granulosus smad 0.0033 0.029 0.029
Schistosoma mansoni intermediate filament proteins 0.0033 0.0287 0.0287
Onchocerca volvulus 0.002 0.0125 0.0395
Echinococcus multilocularis microtubule associated protein 2 0.0771 1 1
Echinococcus granulosus carboxylesterase 5A 0.0072 0.0805 0.0805
Loa Loa (eye worm) carboxylesterase 0.0012 0.0019 0.0022
Brugia malayi PHD-finger family protein 0.0025 0.0194 0.0228
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0125 0.2606
Onchocerca volvulus 0.0012 0.0019 0.0059
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0125 0.0125
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0125 0.0125
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0169 0.2075 0.2075
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0106 0.1331
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0106 0.0805
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0487 0.0487
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0125 0.0125
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0228 0.1934
Brugia malayi Carboxylesterase family protein 0.0012 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0474 0.0474
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.1101 0.1101
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0125 0.0147
Echinococcus multilocularis cysteine protease 0.002 0.0125 0.0125
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0052 0.0061
Brugia malayi hypothetical protein 0.0106 0.1258 0.1481
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0052 0.0061
Brugia malayi MH1 domain containing protein 0.0033 0.029 0.0342
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0162 0.0162
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0374 0.2593
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0019 0.0019
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0287 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0037 0.0058
Leishmania major cathepsin L-like protease 0.0077 0.0872 0.6765
Echinococcus multilocularis neuropeptide s receptor 0.0491 0.631 0.631
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0052 0.0061
Schistosoma mansoni hypothetical protein 0.0169 0.2075 0.2075
Plasmodium vivax SET domain protein, putative 0.0032 0.0275 0.1701
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0342 0.0342
Brugia malayi Cytochrome P450 family protein 0.0028 0.0228 0.0268
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0106 0.0805
Leishmania major cathepsin L-like protease 0.002 0.0125 0.0503
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0074 0.0074
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0106 0.0805
Loa Loa (eye worm) hypothetical protein 0.0364 0.4647 0.5469
Echinococcus multilocularis smad 0.0033 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0072 0.0805 0.0947
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Loa Loa (eye worm) hypothetical protein 0.0042 0.0407 0.0479
Echinococcus granulosus muscleblind protein 0.018 0.2231 0.2231
Echinococcus granulosus Smad4 0.0033 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0015 0.0058 0.0068
Leishmania major cytochrome p450-like protein 0.0028 0.0228 0.1368
Schistosoma mansoni hypothetical protein 0.0169 0.2075 0.2075
Leishmania major cathepsin L-like protease 0.0077 0.0872 0.6765
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0074 0.0087
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0374 0.113
Brugia malayi Cathepsin L-like precursor 0.002 0.0125 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Leishmania major cytochrome p450-like protein 0.0019 0.0106 0.0344
Loa Loa (eye worm) hypothetical protein 0.0175 0.2156 0.2537
Schistosoma mansoni hypothetical protein 0.0016 0.0065 0.0065
Plasmodium vivax vivapain-2 0.002 0.0125 0.0429
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Echinococcus multilocularis neuroligin 0.0012 0.0019 0.0019
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0287 0.1797
Schistosoma mansoni tar DNA-binding protein 0.0657 0.8497 0.8497
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0106 0.1331
Leishmania major cytochrome p450-like protein 0.0019 0.0106 0.0344
Schistosoma mansoni inositol monophosphatase 0.0039 0.0374 0.0374
Echinococcus multilocularis para nitrobenzyl esterase 0.0012 0.0019 0.0019
Onchocerca volvulus 0.0012 0.0019 0.0059
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.1101 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.1101 0.1101
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.032 0.2155
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0221 0.2763 0.3251
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0106 0.0805
Echinococcus granulosus neuropeptide s receptor 0.0491 0.631 0.631
Brugia malayi MH2 domain containing protein 0.0015 0.0052 0.0061
Schistosoma mansoni acetylcholinesterase 0.0012 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0106 0.1331
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.1101 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.029 0.029
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0275 0.0275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0088 0.0088
Onchocerca volvulus 0.0012 0.0019 0.0059
Loa Loa (eye worm) hypothetical protein 0.0072 0.0811 0.0954
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0169 0.2075 0.2075
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0474 0.0558
Schistosoma mansoni cytochrome P450 0.0019 0.0106 0.0106
Schistosoma mansoni tar DNA-binding protein 0.0657 0.8497 0.8497
Onchocerca volvulus 0.0012 0.0019 0.0059
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0125 0.0429
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Echinococcus granulosus BC026374 protein S09 family 0.0012 0.0019 0.0019
Brugia malayi latrophilin 2 splice variant baaae 0.0364 0.4647 0.5469
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0125 0.0125
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.1258 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0374 0.113
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.1101 0.8672
Loa Loa (eye worm) hypothetical protein 0.0032 0.0279 0.0329
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0106 0.1331
Brugia malayi cytochrome P450 0.0019 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.0049 0.0505 0.0594
Brugia malayi MH1 domain containing protein 0.0033 0.029 0.0342
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.1258 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0125 0.0337
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0052 0.0052
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0287 0.0338
Brugia malayi Cathepsin L-like precursor 0.002 0.0125 0.0147
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0487 0.0487
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0872 0.6765
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.2156 0.6814
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0074 0.0077
Leishmania major cathepsin L-like protease 0.002 0.0125 0.0503
Echinococcus multilocularis lamin 0.0033 0.0287 0.0287
Schistosoma mansoni bromodomain containing protein 0.0065 0.071 0.071
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0125 0.0125
Echinococcus multilocularis muscleblind protein 1 0.018 0.2231 0.2231
Onchocerca volvulus 0.002 0.0125 0.0395
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0474 0.0474
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.029 0.029
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0106 0.1331
Loa Loa (eye worm) ctsf protein 0.002 0.0125 0.0147
Loa Loa (eye worm) RNA binding protein 0.0657 0.8497 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0374 0.2593
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0106 0.0805
Loa Loa (eye worm) hypothetical protein 0.002 0.0125 0.0147
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0061
Onchocerca volvulus Cathepsin L homolog 0.002 0.0125 0.0395
Leishmania major cathepsin L-like protease 0.002 0.0125 0.0503
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0125 0.0337
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0044
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0657 0.8497 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0872 0.6765
Schistosoma mansoni hypothetical protein 0.0021 0.0137 0.0137
Trichomonas vaginalis set domain proteins, putative 0.0251 0.3164 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0106 0.1331
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0033 0.0287 0.1819
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0074 0.0087
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.1258 1
Echinococcus multilocularis acetylcholinesterase 0.0072 0.0805 0.0805
Loa Loa (eye worm) carboxylesterase 0.0012 0.0019 0.0022
Plasmodium vivax vivapain-2 0.002 0.0125 0.0429
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0106 0.1331
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0106 0.0805
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.032 0.4608
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.1101 0.8672
Onchocerca volvulus 0.0033 0.0287 0.0908
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0169 0.2075 0.2075
Schistosoma mansoni hypothetical protein 0.0019 0.0106 0.0106
Brugia malayi Cathepsin L-like precursor 0.002 0.0125 0.0147
Echinococcus granulosus cathepsin l1 0.002 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0125 0.0337
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0162 0.0162
Brugia malayi Calcitonin receptor-like protein seb-1 0.0533 0.6864 0.8077
Loa Loa (eye worm) hypothetical protein 0.0182 0.2259 0.2658
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0022

Activities

Activity type Activity value Assay description Source Reference
GI (functional) = 2 % Antitrypanosomal activity against Trypanosoma cruzi Tulahuen 2 epimastigotes assessed as growth inhibition at 25 uM after 5 days relative to control ChEMBL. 21506600
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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