Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.057 | 0.1927 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.2281 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1983 | 0.1852 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.2281 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0162 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.057 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3146 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.2281 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0162 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3146 | 0.3034 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.057 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.057 | 0.1368 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3146 | 0.3034 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.2281 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3146 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.2281 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1983 | 0.1852 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.2281 | 0.2154 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3146 | 0.3034 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1983 | 0.1852 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0162 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.2281 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.2281 | 0.2154 |
Brugia malayi | hypothetical protein | 0.0025 | 0.057 | 0.1812 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.057 | 0.1927 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3146 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1983 | 0.1852 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0162 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.2281 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.2281 | 0.2154 |
Echinococcus multilocularis | geminin | 0.0169 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.2281 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.2281 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.2281 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3146 | 0.3034 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3146 | 0.3034 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1983 | 0.1852 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1983 | 0.1852 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.2281 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.057 | 0.1927 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3146 | 0.3034 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.057 | 0.1927 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3146 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.1983 | 0.6304 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.057 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.057 | 0.1927 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.2281 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.2281 | 0.7101 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.2281 | 0.725 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.2281 | 0.2154 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1983 | 0.1852 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0162 | 0.0514 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.2281 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0162 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3146 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3146 | 0.3034 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.2281 | 1 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3146 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.1983 | 0.6103 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.2281 | 0.2154 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.