Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | NAC domain-containing protein | 0.0041 | 0.9423 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 1 | 1 |
Schistosoma mansoni | transcription factor btf3 | 0.0041 | 0.9423 | 0.9423 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0 | 0.5 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0041 | 0.9423 | 1 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0041 | 0.9423 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.9423 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.9423 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 1 | 1 |
Leishmania major | basic transcription factor 3a, putative | 0.0041 | 0.9423 | 1 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0041 | 0.9423 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 1 | 1 |
Echinococcus granulosus | transcription factor btf3 | 0.0041 | 0.9423 | 0.9423 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0041 | 0.9423 | 1 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0041 | 0.9423 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.9423 | 0.9423 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0 | 0.5 |
Loa Loa (eye worm) | ICD-1 protein | 0.0041 | 0.9423 | 1 |
Brugia malayi | beta-NAC-like protein | 0.0041 | 0.9423 | 0.9423 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 1 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 1 | 1 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0041 | 0.9423 | 0.9423 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0 | 0.5 |
Echinococcus multilocularis | transcription factor btf3 | 0.0041 | 0.9423 | 0.9423 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.9423 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.