Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tar DNA binding protein | 0.0135 | 0.2603 | 0.1553 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2603 | 0.1553 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.013 | 0.243 | 0.3086 |
Loa Loa (eye worm) | glutaminase | 0.0298 | 0.7875 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0135 | 0.2603 | 0.1553 |
Brugia malayi | TAR-binding protein | 0.0135 | 0.2603 | 0.3305 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0364 | 1 | 1 |
Schistosoma mansoni | glutaminase | 0.0298 | 0.7875 | 0.7574 |
Schistosoma mansoni | inositol transporter | 0.0364 | 1 | 1 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0093 | 0.1243 | 0.5 |
Echinococcus multilocularis | solute carrier family 5 | 0.0364 | 1 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0298 | 0.7875 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0364 | 1 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.013 | 0.243 | 0.3086 |
Schistosoma mansoni | inositol transporter | 0.0364 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2603 | 0.1553 |
Loa Loa (eye worm) | RNA binding protein | 0.0135 | 0.2603 | 0.3305 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1243 | 0.1579 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1243 | 0.1579 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0135 | 0.2603 | 0.3305 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0364 | 1 | 1 |
Onchocerca volvulus | 0.0093 | 0.1243 | 0.5 | |
Brugia malayi | GH02984p | 0.0093 | 0.1243 | 0.1579 |
Mycobacterium ulcerans | glutaminase | 0.0298 | 0.7875 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2603 | 0.1553 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0135 | 0.2603 | 0.3305 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2603 | 0.1553 |
Brugia malayi | MH2 domain containing protein | 0.013 | 0.243 | 0.3086 |
Schistosoma mansoni | tar DNA-binding protein | 0.0135 | 0.2603 | 0.1553 |
Brugia malayi | Sodium:solute symporter family protein | 0.0093 | 0.1243 | 0.1579 |
Brugia malayi | RNA binding protein | 0.0135 | 0.2603 | 0.3305 |
Brugia malayi | glutaminase DH11.1 | 0.0298 | 0.7875 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.0364 | 1 | 1 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0364 | 1 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0298 | 0.7875 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0135 | 0.2603 | 0.3305 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
K (binding) | = 1.7 M-1 | DNA binding constant | ChEMBL. | 10522692 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.