Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0348 | 0.2027 | 0.4228 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0076 | 0.0302 | 0.0161 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Giardia lamblia | Glycogen phosphorylase | 0.0348 | 0.2027 | 0.2458 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.0157 | 0.0776 |
Leishmania major | thymidylate kinase-like protein | 0.0152 | 0.0782 | 0.1573 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0035 | 0.0041 | 0.0021 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0078 | 0.0314 | 0.0575 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Trypanosoma brucei | cytidine deaminase | 0.0057 | 0.0181 | 0.0291 |
Schistosoma mansoni | glycogen phosphorylase | 0.015 | 0.0773 | 0.076 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0045 | 0.0025 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0348 | 0.2027 | 0.4228 |
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0366 | 0.2141 | 0.2125 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0045 | 0.022 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.015 | 0.0773 | 0.5983 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.002 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0455 | 0.2247 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0774 | 0.4733 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.002 | 0.0099 |
Echinococcus multilocularis | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0072 | 0.0274 | 0.0254 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0195 | 0.0177 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.041 | 0.2023 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0035 | 0.0041 | 0.0021 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.015 | 0.0773 | 0.1555 |
Echinococcus multilocularis | solute carrier family 28 | 0.0366 | 0.2141 | 0.2125 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0076 | 0.0302 | 0.0548 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.006 | 0.0197 | 0.0324 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0044 | 0.0024 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0152 | 0.0782 | 0.372 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0314 | 0.1551 |
Mycobacterium ulcerans | cytidine deaminase | 0.0057 | 0.0181 | 0.1852 |
Onchocerca volvulus | 0.0057 | 0.0181 | 0.0689 | |
Schistosoma mansoni | thymidine kinase | 0.1593 | 0.9935 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0045 | 0.022 |
Leishmania major | thymidine kinase, putative | 0.0774 | 0.4733 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0055 | 0.0165 | 0.0145 |
Echinococcus multilocularis | lamin | 0.0053 | 0.0157 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0045 | 0.022 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0774 | 0.4733 | 1 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0152 | 0.0782 | 0.1573 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Schistosoma mansoni | glycogen phosphorylase | 0.0348 | 0.2027 | 0.2024 |
Giardia lamblia | Hypothetical protein | 0.0072 | 0.0274 | 0.0123 |
Onchocerca volvulus | 0.0053 | 0.0157 | 0.0568 | |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0234 | 0.1303 | 0.1286 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0044 | 0.0025 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0152 | 0.0782 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0738 | 0.0724 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0348 | 0.2027 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0077 | 0.0309 | 0.0565 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0044 | 0.0025 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0348 | 0.2027 | 0.2011 |
Leishmania major | cytidine deaminase-like protein | 0.0057 | 0.0181 | 0.0291 |
Brugia malayi | thymidylate kinase | 0.0152 | 0.0782 | 0.3858 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0774 | 0.4733 | 1 |
Trypanosoma brucei | thymidine kinase | 0.0774 | 0.4733 | 1 |
Mycobacterium ulcerans | thymidylate kinase | 0.0152 | 0.0782 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0309 | 0.0565 |
Entamoeba histolytica | thymidine kinase, putative | 0.0774 | 0.4733 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0145 | 0.0738 | 0.0719 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0044 | 0.0025 |
Giardia lamblia | Thymidine kinase | 0.0774 | 0.4733 | 0.6061 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0348 | 0.2027 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0134 | 0.0669 | 0.065 |
Echinococcus multilocularis | thymidine kinase | 0.1593 | 0.9935 | 0.9934 |
Echinococcus granulosus | thymidylate kinase | 0.0152 | 0.0782 | 0.0768 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0077 | 0.0309 | 0.029 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0348 | 0.2027 | 0.2011 |
Echinococcus granulosus | thymidine kinase | 0.1593 | 0.9935 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0151 | 0.0745 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.0455 | 0.2247 |
Schistosoma mansoni | hypothetical protein | 0.0134 | 0.0669 | 0.0655 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0078 | 0.0314 | 0.0575 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.041 | 0.2023 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0078 | 0.0314 | 0.0262 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0774 | 0.4733 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0045 | 0.022 |
Echinococcus granulosus | solute carrier family 28 | 0.0366 | 0.2141 | 0.2139 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.015 | 0.0773 | 0.9882 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0045 | 0.022 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0078 | 0.0314 | 0.3657 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0076 | 0.0302 | 0.0548 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0076 | 0.0302 | 0.0282 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.0157 | 0.0776 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0234 | 0.1303 | 0.1294 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0076 | 0.0302 | 0.1489 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0045 | 0.022 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0134 | 0.0669 | 0.0655 |
Echinococcus granulosus | geminin | 0.0348 | 0.2027 | 0.2025 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Trypanosoma cruzi | cytidine deaminase-like protein, putative | 0.0057 | 0.0181 | 0.0291 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0055 | 0.0165 | 0.0146 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0152 | 0.0782 | 0.1573 |
Giardia lamblia | Deoxynucleoside kinase | 0.124 | 0.769 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0309 | 0.0565 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0348 | 0.2027 | 0.4228 |
Schistosoma mansoni | ap endonuclease | 0.0076 | 0.0302 | 0.0284 |
Echinococcus granulosus | cytidine deaminase | 0.0057 | 0.0181 | 0.0163 |
Brugia malayi | Inositol-1 | 0.0077 | 0.0309 | 0.1527 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0077 | 0.0309 | 0.3591 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0348 | 0.2027 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0076 | 0.0302 | 0.0548 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0045 | 0.022 |
Loa Loa (eye worm) | thymidylate kinase | 0.0152 | 0.0782 | 0.3858 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0254 | 0.1253 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.015 | 0.0773 | 0.1555 |
Echinococcus granulosus | glycogen phosphorylase | 0.0348 | 0.2027 | 0.2024 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.041 | 0.0393 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0314 | 0.1551 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0738 | 0.0724 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0152 | 0.0782 | 1 |
Echinococcus granulosus | thymidine kinase | 0.1593 | 0.9935 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0195 | 0.0321 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0077 | 0.0309 | 0.016 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.0157 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1303 | 0.6429 |
Giardia lamblia | Hypothetical protein | 0.0072 | 0.0274 | 0.0123 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0195 | 0.0177 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.0157 | 0.0776 |
Echinococcus multilocularis | cytidine deaminase | 0.0057 | 0.0181 | 0.0161 |
Loa Loa (eye worm) | deoxynucleoside kinase | 0.0072 | 0.0274 | 0.1351 |
Mycobacterium leprae | PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) | 0.0057 | 0.0181 | 0.1852 |
Schistosoma mansoni | lipoxygenase | 0.0055 | 0.0165 | 0.0146 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0195 | 0.1237 |
Echinococcus granulosus | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0072 | 0.0274 | 0.0256 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0076 | 0.0302 | 0.3487 |
Leishmania major | hypothetical protein, conserved | 0.0078 | 0.0314 | 0.0575 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0152 | 0.0782 | 0.6054 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0366 | 0.2141 | 0.2139 |
Schistosoma mansoni | inositol monophosphatase | 0.0077 | 0.0309 | 0.0292 |
Schistosoma mansoni | inositol monophosphatase | 0.0077 | 0.0309 | 0.0292 |
Toxoplasma gondii | cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein | 0.0057 | 0.0181 | 0.1852 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0045 | 0.022 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0254 | 0.0236 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.0072 | 0.0274 | 0.0256 |
Onchocerca volvulus | 0.0053 | 0.0157 | 0.0568 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0045 | 0.022 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0152 | 0.0782 | 0.1573 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0045 | 0.0025 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0152 | 0.0782 | 0.1573 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0078 | 0.0314 | 0.0262 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0077 | 0.0309 | 0.0292 |
Mycobacterium tuberculosis | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) | 0.0057 | 0.0181 | 0.1121 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.041 | 0.0393 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.0157 | 0.0138 |
Echinococcus multilocularis | thymidine kinase | 0.1593 | 0.9935 | 0.9934 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.1593 | 0.9935 | 1 |
Brugia malayi | Deoxynucleoside kinase family protein | 0.0072 | 0.0274 | 0.1351 |
Brugia malayi | hypothetical protein | 0.005 | 0.0139 | 0.0684 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0076 | 0.0302 | 0.0548 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.0455 | 0.2247 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0195 | 0.2043 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0227 | 0.1263 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.002 | 0.0099 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0121 | 0.0599 |
Echinococcus multilocularis | thymidylate kinase | 0.0152 | 0.0782 | 0.0763 |
Leishmania major | hypothetical protein, conserved | 0.006 | 0.0197 | 0.0324 |
Schistosoma mansoni | hypothetical protein | 0.0152 | 0.0782 | 0.0768 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.015 | 0.0773 | 0.1555 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0366 | 0.2141 | 0.2139 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.006 | 0.0197 | 0.0324 |
Brugia malayi | carbohydrate phosphorylase | 0.0348 | 0.2027 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Onchocerca volvulus | 0.0048 | 0.0121 | 0.0387 | |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0274 | 0.0489 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0309 | 0.0565 |
Loa Loa (eye worm) | inositol-1 | 0.0077 | 0.0309 | 0.1527 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0157 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0045 | 0.022 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0076 | 0.0302 | 0.0548 |
Plasmodium vivax | thymidylate kinase, putative | 0.0152 | 0.0782 | 1 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0348 | 0.2027 | 0.2024 |
Giardia lamblia | Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative | 0.0072 | 0.0274 | 0.0123 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0274 | 0.0489 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0152 | 0.0782 | 0.1573 |
Schistosoma mansoni | hypothetical protein | 0.0348 | 0.2027 | 0.2025 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.002 | 0.0099 |
Schistosoma mansoni | thymidylate kinase | 0.0152 | 0.0782 | 0.0768 |
Schistosoma mansoni | lamin | 0.0053 | 0.0157 | 0.0138 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0076 | 0.0302 | 0.0549 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0078 | 0.0314 | 0.0575 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0045 | 0.022 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0077 | 0.0309 | 0.0565 |
Schistosoma mansoni | lamin | 0.0053 | 0.0157 | 0.0138 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.041 | 0.0393 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0069 | 0.0258 | 0.2893 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0152 | 0.0782 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0254 | 0.1253 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0152 | 0.0782 | 0.1573 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0045 | 0.0025 |
Brugia malayi | hypothetical protein | 0.0234 | 0.1303 | 0.6429 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0076 | 0.0302 | 0.0548 |
Schistosoma mansoni | ap endonuclease | 0.0076 | 0.0302 | 0.0284 |
Echinococcus multilocularis | geminin | 0.0348 | 0.2027 | 0.2011 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0195 | 0.2043 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0077 | 0.0309 | 0.0565 |
Plasmodium falciparum | thymidylate kinase | 0.0152 | 0.0782 | 1 |
Echinococcus multilocularis | transfer RNA-Ile | 0.1593 | 0.9935 | 0.9934 |
Echinococcus multilocularis | musashi | 0.0053 | 0.0157 | 0.0137 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.0455 | 0.2247 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0077 | 0.0309 | 0.0565 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0348 | 0.2027 | 0.4228 |
Toxoplasma gondii | thymidylate kinase | 0.0152 | 0.0782 | 1 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0057 | 0.0181 | 0.0291 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0045 | 0.022 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.041 | 0.0393 |
Entamoeba histolytica | cytidine deaminase, putative | 0.0057 | 0.0181 | 0.0292 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0195 | 0.2043 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0274 | 0.0489 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0195 | 0.0177 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0077 | 0.0309 | 0.3591 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0072 | 0.0274 | 0.0489 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.0157 | 0.0776 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.0157 | 0.0138 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0076 | 0.0302 | 0.3487 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0045 | 0.0025 |
Echinococcus granulosus | glycogen phosphorylase | 0.0348 | 0.2027 | 0.2024 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0274 | 0.0489 |
Schistosoma mansoni | hypothetical protein | 0.0226 | 0.1253 | 0.1244 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0041 | 0.0021 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0076 | 0.0302 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0348 | 0.2027 | 0.2025 |
Echinococcus granulosus | lamin | 0.0053 | 0.0157 | 0.0138 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0121 | 0.0102 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.041 | 0.0393 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0057 | 0.0181 | 0.0291 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0348 | 0.2027 | 0.2011 |
Schistosoma mansoni | thymidylate kinase | 0.0152 | 0.0782 | 0.0768 |
Trypanosoma brucei | RNA helicase, putative | 0.0226 | 0.1253 | 0.2578 |
Brugia malayi | cytidine deaminase, identical | 0.0057 | 0.0181 | 0.0894 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0076 | 0.0302 | 0.2111 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.0493 | 0.0477 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0076 | 0.0302 | 0.1489 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0077 | 0.0309 | 0.0565 |
Giardia lamblia | CDC8 | 0.0152 | 0.0782 | 0.08 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0774 | 0.4733 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0195 | 0.2043 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0044 | 0.0219 |
Onchocerca volvulus | 0.0057 | 0.0181 | 0.0689 | |
Toxoplasma gondii | exonuclease III APE | 0.0076 | 0.0302 | 0.3487 |
Schistosoma mansoni | glycogen phosphorylase | 0.0348 | 0.2027 | 0.2024 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.0157 | 0.0138 |
Echinococcus multilocularis | sodium:nucleoside cotransporter 2 | 0.0239 | 0.1333 | 0.1315 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.041 | 0.0391 |
Trypanosoma cruzi | cytidine deaminase-like protein | 0.0057 | 0.0181 | 0.0291 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0195 | 0.0176 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.041 | 0.0391 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0078 | 0.0314 | 0.3657 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0152 | 0.0782 | 0.1573 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0121 | 0.0102 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0069 | 0.0258 | 0.1752 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 26.1 uM | PUBCHEM_BIOASSAY: Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1209, AID1220, AID1545, AID1553, AID1574, AID1620] | ChEMBL. | No reference |
IC50 (binding) | = 95.4 uM | PUBCHEM_BIOASSAY: Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1545, AID1574] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.