Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0017 | 0.0021 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0063 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Onchocerca volvulus | 0.0038 | 0.0063 | 0.0607 | |
Onchocerca volvulus | 0.0044 | 0.0075 | 0.0753 | |
Schistosoma mansoni | chromobox protein | 0.003 | 0.0047 | 0.0047 |
Schistosoma mansoni | protein kinase C mu | 0.0043 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.003 | 0.0047 | 0.0129 |
Schistosoma mansoni | glycogen phosphorylase | 0.0183 | 0.0348 | 0.0348 |
Brugia malayi | MH2 domain containing protein | 0.0051 | 0.0089 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1858 | 0.3643 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0314 | 0.0606 | 0.1663 |
Brugia malayi | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Schistosoma mansoni | chromobox protein | 0.003 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0014 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0131 | 0.0131 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0314 | 0.0606 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0021 | 0.0058 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0423 | 0.082 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1858 | 0.3643 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1858 | 0.3643 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1858 | 0.3643 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1858 | 0.3643 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1858 | 0.3643 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0314 | 0.0606 | 0.0606 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0018 | 0.0024 | 0.0119 |
Brugia malayi | Carboxylesterase family protein | 0.0314 | 0.0606 | 0.1663 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0423 | 0.082 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0423 | 0.082 | 0.2251 |
Echinococcus multilocularis | chromobox protein 1 | 0.003 | 0.0047 | 0.0129 |
Trichomonas vaginalis | chromobox protein, putative | 0.0018 | 0.0024 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0075 | 0.0205 |
Brugia malayi | chromobox protein homolog 3 | 0.0017 | 0.0021 | 0.0058 |
Echinococcus granulosus | chromobox protein 1 | 0.003 | 0.0047 | 0.0129 |
Trichomonas vaginalis | chromobox protein, putative | 0.003 | 0.0047 | 0.0437 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0038 | 0.0063 | 0.0173 |
Brugia malayi | Carboxylesterase family protein | 0.0314 | 0.0606 | 0.1663 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0423 | 0.082 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0423 | 0.082 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0314 | 0.0606 | 0.7348 |
Echinococcus granulosus | neuroligin | 0.0314 | 0.0606 | 0.1663 |
Echinococcus granulosus | glycogen phosphorylase | 0.0423 | 0.082 | 0.2251 |
Brugia malayi | C1-like domain containing protein | 0.0043 | 0.0072 | 0.0199 |
Echinococcus multilocularis | geminin | 0.0072 | 0.0131 | 0.0359 |
Echinococcus multilocularis | acetylcholinesterase | 0.1858 | 0.3643 | 1 |
Onchocerca volvulus | 0.0314 | 0.0606 | 0.734 | |
Echinococcus multilocularis | neuroligin | 0.0314 | 0.0606 | 0.1663 |
Echinococcus granulosus | glycogen phosphorylase | 0.0423 | 0.082 | 0.2251 |
Loa Loa (eye worm) | carboxylesterase | 0.0314 | 0.0606 | 0.1663 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0051 | 0.0089 | 0.0243 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0314 | 0.0606 | 0.1663 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0423 | 0.082 | 0.2251 |
Brugia malayi | Carboxylesterase family protein | 0.1858 | 0.3643 | 1 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0926 | 0.1809 | 0.1809 |
Brugia malayi | carbohydrate phosphorylase | 0.0423 | 0.082 | 0.2251 |
Echinococcus granulosus | geminin | 0.0072 | 0.0131 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.1858 | 0.3643 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.003 | 0.0047 | 0.0437 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1858 | 0.3643 | 0.3643 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0423 | 0.082 | 1 |
Onchocerca volvulus | 0.0043 | 0.0072 | 0.0722 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0314 | 0.0606 | 0.1663 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0043 | 0.0072 | 0.0199 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0314 | 0.0606 | 0.7348 |
Trichomonas vaginalis | chromobox protein, putative | 0.0018 | 0.0024 | 0.0149 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0314 | 0.0606 | 0.0606 |
Onchocerca volvulus | 0.0314 | 0.0606 | 0.734 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0314 | 0.0606 | 0.1663 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0072 | 0.0198 |
Loa Loa (eye worm) | carboxylesterase | 0.1858 | 0.3643 | 1 |
Onchocerca volvulus | 0.0314 | 0.0606 | 0.734 | |
Onchocerca volvulus | 0.0314 | 0.0606 | 0.734 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0017 | 0.0021 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Schistosoma mansoni | acetylcholinesterase | 0.0314 | 0.0606 | 0.0606 |
Echinococcus granulosus | chromobox protein 1 | 0.003 | 0.0047 | 0.0129 |
Echinococcus multilocularis | acetylcholinesterase | 0.1858 | 0.3643 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0314 | 0.0606 | 0.1663 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0314 | 0.0606 | 0.0606 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0314 | 0.0606 | 0.1663 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0017 | 0.0021 | 0.0119 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0131 | 0.0131 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0314 | 0.0606 | 0.1663 |
Loa Loa (eye worm) | carboxylesterase | 0.0314 | 0.0606 | 0.1663 |
Brugia malayi | Heterochromatin protein 1 | 0.003 | 0.0047 | 0.0129 |
Schistosoma mansoni | glycogen phosphorylase | 0.0423 | 0.082 | 0.082 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Brugia malayi | Carboxylesterase family protein | 0.1858 | 0.3643 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0423 | 0.082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Schistosoma mansoni | gliotactin | 0.0314 | 0.0606 | 0.0606 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0423 | 0.082 | 0.2251 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0051 | 0.0089 | 0.0243 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0314 | 0.0606 | 0.0606 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Schistosoma mansoni | glycogen phosphorylase | 0.0423 | 0.082 | 0.082 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0314 | 0.0606 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0314 | 0.0606 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0606 | 0.1663 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0043 | 0.0072 | 0.0199 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0423 | 0.082 | 0.2251 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0314 | 0.0606 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.003 | 0.0047 | 0.0129 |
Brugia malayi | Carboxylesterase family protein | 0.0314 | 0.0606 | 0.1663 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0423 | 0.082 | 0.2251 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0063 | 0.0173 |
Onchocerca volvulus | 0.0314 | 0.0606 | 0.734 | |
Giardia lamblia | Glycogen phosphorylase | 0.0423 | 0.082 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0314 | 0.0606 | 0.0606 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.