Detailed information for compound 1559325

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 513.573 | Formula: C22H27N9O4S
  • H donors: 6 H acceptors: 5 LogP: 0.39 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 3
  • SMILES: NC(=NCCC[C@@H](C(=O)N[C@H](C(=O)N)Cc1c([nH]c2c1cccc2)Sc1ncccc1[N+](=O)[O-])N)N
  • InChi: 1S/C22H27N9O4S/c23-14(6-3-10-28-22(25)26)19(33)29-16(18(24)32)11-13-12-5-1-2-7-15(12)30-20(13)36-21-17(31(34)35)8-4-9-27-21/h1-2,4-5,7-9,14,16,30H,3,6,10-11,23H2,(H2,24,32)(H,29,33)(H4,25,26,28)/t14-,16-/m0/s1
  • InChiKey: IHNRBROFCAVGEN-HOCLYGCPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.075 0.1258
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.1861 0.1861
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.1861 0.8
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0314 0.0371
Loa Loa (eye worm) hypothetical protein 0.0074 0.075 0.3224
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0175 0.0752
Mycobacterium leprae conserved hypothetical protein 0.0074 0.075 0.4265
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0162 0.046
Brugia malayi chromobox protein homolog 3 0.0039 0.0305 0.131
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.03 0.0354
Loa Loa (eye worm) hypothetical protein 0.0199 0.2326 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0268 0.0766
Schistosoma mansoni hypothetical protein 0.0029 0.018 0.0213
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.075 0.1258
Onchocerca volvulus 0.0019 0.0048 0.0109
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.005 0.0059
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0689 0.1975
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0056 0.0522 0.0615
Toxoplasma gondii histone deacetylase HDAC3 0.0062 0.0598 0.5135
Brugia malayi histone deacetylase 3 (HD3) 0.0062 0.0598 0.2573
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0024 0.0117 0.0892
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.005 0.0216
Mycobacterium ulcerans peptide amidase, GatA 0.0024 0.0117 0.0549
Echinococcus granulosus fatty acid amide hydrolase 1 0.0024 0.0117 0.0138
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0048 0.0208
Trypanosoma cruzi histone deacetylase 1, putative 0.0062 0.0598 0.5854
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1001 0.2868
Echinococcus granulosus chromobox protein 1 0.0069 0.0689 0.0813
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0024 0.0117 0.0549
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0314 0.0314
Trypanosoma cruzi metacaspase 5, putative 0.0024 0.012 0.0917
Brugia malayi Dopamine receptor 0.0019 0.0048 0.0208
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0342 0.3158
Echinococcus multilocularis zinc finger protein 0.0019 0.006 0.006
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0048 0.0057
Schistosoma mansoni fatty-acid amide hydrolase 0.0199 0.2326 0.2742
Brugia malayi Bromodomain containing protein 0.0035 0.0255 0.1096
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0035 0.0256 0.1099
Trypanosoma cruzi amidase, putative 0.0024 0.0117 0.0892
Brugia malayi exodeoxyribonuclease III family protein 0.0017 0.0031 0.0132
Schistosoma mansoni tar DNA-binding protein 0.0063 0.061 0.0719
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0314 0.0371
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0038 0.0076
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0314 0.0371
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.005 0.0059
Onchocerca volvulus 0.0074 0.075 0.7395
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.075 0.1258
Schistosoma mansoni cpg binding protein 0.0032 0.0218 0.0256
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Trypanosoma cruzi metacaspase, putative 0.0024 0.012 0.0917
Schistosoma mansoni biogenic amine receptor 0.0019 0.0048 0.0057
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0024 0.0117 0.0161
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0268 0.0316
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0314 0.1352
Schistosoma mansoni tar DNA-binding protein 0.0063 0.061 0.0719
Echinococcus granulosus somatostatin receptor 0.0019 0.0048 0.0057
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0048 0.0057
Onchocerca volvulus 0.0019 0.0048 0.0109
Brugia malayi Serotonin receptor 0.0019 0.0048 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0048 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Echinococcus multilocularis serotonin receptor 0.0019 0.0048 0.0048
Echinococcus multilocularis chromobox protein 1 0.0069 0.0689 0.0689
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0337
Trypanosoma cruzi metacaspase, putative 0.0024 0.012 0.0917
Leishmania major metacaspase, putative 0.0024 0.012 0.0805
Echinococcus multilocularis caspase 2 0.0024 0.012 0.012
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0402 0.1149
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0048 0.0208
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.001 0.0012
Schistosoma mansoni thyroid hormone receptor 0.004 0.0314 0.0371
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.005 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0048 0.0057
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0268 0.1154
Trichomonas vaginalis esterase, putative 0.0074 0.075 0.2149
Schistosoma mansoni chromobox protein 0.0069 0.0689 0.0813
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0112 0.0516
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Plasmodium vivax histone deacetylase, putative 0.0018 0.0038 0.0102
Mycobacterium ulcerans amidase 0.0024 0.0117 0.0549
Echinococcus granulosus histone deacetylase 6 0.0018 0.0038 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0314 0.1352
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0048 0.0057
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.005 0.0216
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0112 0.0236
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Brugia malayi nuclear receptor NHR-88 0.0019 0.005 0.0216
Schistosoma mansoni nuclear hormone receptor 0.0019 0.005 0.0059
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0268 0.0268
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0048 0.0208
Trypanosoma brucei metacaspase MCA3 0.0024 0.012 0.0917
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0579 0.0683
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0158
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0112 0.0516
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0314 0.2871
Echinococcus granulosus zinc finger protein 0.0019 0.006 0.0071
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0112 0.0736
Entamoeba histolytica hypothetical protein 0.0036 0.0266 0.0682
Echinococcus granulosus histone deacetylase 3 0.0062 0.0598 0.0706
Echinococcus multilocularis somatostatin receptor 0.0019 0.0048 0.0048
Brugia malayi tailless protein 0.0019 0.005 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0039 0.0109
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Giardia lamblia Kinase, PLK 0.0094 0.1001 0.2808
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0268 0.0766
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Toxoplasma gondii histone deacetylase HDAC2 0.0062 0.0598 0.5135
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.005 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0024 0.0112 0.0482
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0305 0.2772
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0048 0.0208
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0105 0.1137 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.005 0.005
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0112 0.0482
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0079
Loa Loa (eye worm) histone deacetylase 7A 0.0018 0.0038 0.0163
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.018 0.1355
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0048 0.0208
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi nuclear hormone receptor 0.004 0.0314 0.1352
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0048 0.0057
Brugia malayi putative amidase 0.0024 0.0117 0.0504
Onchocerca volvulus 0.0019 0.0048 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1001 0.2868
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0024 0.0117 0.0034
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.3485 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0078 0.0092
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.005 0.0216
Brugia malayi jmjC domain containing protein 0.0095 0.1014 0.4358
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0048 0.0048
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0039 0.0109
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Echinococcus multilocularis X box binding protein 1 0.0287 0.3433 0.3433
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0048 0.0208
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0112 0.0482
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.018 0.0213
Schistosoma mansoni tar DNA-binding protein 0.0063 0.061 0.0719
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0031 0.0084
Echinococcus granulosus histone deacetylase 0.0018 0.0038 0.0045
Loa Loa (eye worm) amidase 0.0024 0.0117 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0314 0.1352
Schistosoma mansoni opsin-like receptor 0.0019 0.0048 0.0057
Plasmodium vivax histone deacetylase 1, putative 0.0062 0.0598 0.7894
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni nuclear receptor 0.0019 0.005 0.0059
Schistosoma mansoni amine GPCR 0.0019 0.0048 0.0057
Echinococcus granulosus serotonin receptor 0.0019 0.0048 0.0057
Brugia malayi conserved hypotetical protein 0.0019 0.005 0.0216
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0598 0.1714
Trypanosoma cruzi metacaspase, putative 0.0024 0.012 0.0917
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Plasmodium falciparum histone deacetylase 1 0.0062 0.0598 1
Brugia malayi TAR-binding protein 0.0063 0.061 0.2622
Schistosoma mansoni histamine h1 receptor 0.0019 0.0048 0.0057
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0048 0.0048
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0048 0.0057
Brugia malayi putative neuropeptide receptor 0.0019 0.0048 0.0208
Brugia malayi PHD-finger family protein 0.0024 0.0121 0.0522
Entamoeba histolytica histone deacetylase, putative 0.0062 0.0598 0.1644
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0078 0.0078
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Echinococcus granulosus histone deacetylase 6 0.0018 0.0038 0.0045
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0598 0.1714
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0112 0.0736
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0337
Schistosoma mansoni alpha-glucosidase 0.0139 0.1576 0.1858
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0314 0.1352
Echinococcus multilocularis tar DNA binding protein 0.0063 0.061 0.061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.1861 0.1861
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0024 0.0117 0.0034
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.005 0.005
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.075 0.4561
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0048 0.0048
Plasmodium vivax hypothetical protein, conserved 0.0029 0.018 0.2083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0314 0.1352
Trypanosoma brucei metacaspase 0.0024 0.012 0.0917
Echinococcus multilocularis histone deacetylase 0.0018 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0048 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0048 0.0057
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0473 0.5792 1
Echinococcus granulosus caspase 2 0.0024 0.012 0.0141
Onchocerca volvulus 0.0019 0.0048 0.0109
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0199 0.2326 0.2326
Onchocerca volvulus 0.0024 0.0112 0.0769
Echinococcus granulosus allatostatin A receptor 0.0019 0.0048 0.0057
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0268 0.0766
Brugia malayi larval opioid receptor 0.0019 0.0048 0.0208
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0105 0.1137 0.1137
Brugia malayi nuclear receptor RXR 0.0021 0.0078 0.0337
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0048 0.0208
Brugia malayi nuclear receptor NHR-67 0.0019 0.005 0.0216
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0048 0.0057
Onchocerca volvulus 0.0019 0.0048 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0018 0.0022
Brugia malayi MH2 domain containing protein 0.0119 0.1314 0.5649
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0048 0.0057
Schistosoma mansoni histone deacetylase 0.0062 0.0598 0.0706
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0314 0.0371
Echinococcus granulosus FTZ F1 alpha 0.0411 0.5007 0.5903
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0048 0.0048
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0268 0.0766
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0314 0.0371
Echinococcus multilocularis histone deacetylase 7 0.0018 0.0038 0.0038
Schistosoma mansoni caspase-3 (C14 family) 0.0024 0.012 0.0141
Onchocerca volvulus Serine\/threonine kinase homolog 0.0094 0.1001 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0314 0.0314
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.001 0.001
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus multilocularis serotonin receptor 0.0019 0.0048 0.0048
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0689 0.1975
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0048 0.0057
Echinococcus granulosus histone lysine methyltransferase setb 0.0016 0.0018 0.0022
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0048 0.0048
Brugia malayi ORL1-like opioid receptor 0.0019 0.0048 0.0208
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0048 0.0208
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.03 0.129
Onchocerca volvulus 0.0019 0.0048 0.0109
Schistosoma mansoni myosin xvIII 0.0019 0.0048 0.0057
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.03 0.0354
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.005 0.005
Brugia malayi Dopamine receptor protein 2 0.0019 0.0048 0.0208
Brugia malayi AKH receptor 0.0019 0.0048 0.0208
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0024 0.0117 0.0138
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.1014 0.1014
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0268 0.0766
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.005 0.0059
Schistosoma mansoni opsin-like receptor 0.0019 0.0048 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0039 0.0109
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0112 0.0516
Echinococcus granulosus fatty acid amide hydrolase 1 0.0199 0.2326 0.2742
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0342 0.0978
Loa Loa (eye worm) hypothetical protein 0.0074 0.075 0.3224
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0048 0.0048
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Brugia malayi RNA binding protein 0.0063 0.061 0.2622
Schistosoma mansoni opsin-like receptor 0.0019 0.0048 0.0057
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0112 0.0236
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni aldehyde dehydrogenase 0.0105 0.1137 0.134
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0048 0.0208
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0048 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0314 0.1352
Brugia malayi PHD-finger family protein 0.0029 0.018 0.0776
Giardia lamblia Histone deacetylase 0.0062 0.0598 0.1644
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0078 0.0337
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Schistosoma mansoni kinase 0.0048 0.0417 0.0492
Schistosoma mansoni amine GPCR 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.005 0.0442 0.1901
Echinococcus granulosus sex peptide receptor 0.0019 0.0048 0.0057
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0038 0.0076
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.1861 0.8
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0037 0.0108
Echinococcus granulosus cpg binding protein 0.0032 0.0218 0.0256
Brugia malayi hypothetical protein 0.0019 0.005 0.0216
Brugia malayi Nuclear hormone receptor E75 0.0019 0.005 0.0216
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.005 0.0127
Leishmania major histone deacetylase, putative 0.0062 0.0598 0.5135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0048 0.0057
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0048 0.0109
Leishmania major histone deacetylase, putative 0.0018 0.0038 0.0066
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0314 0.1352
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0048 0.0048
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0314 0.0314
Mycobacterium ulcerans aldehyde dehydrogenase 0.0105 0.1137 0.7013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0048 0.0048
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0112 0.0482
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.075 0.7415
Brugia malayi Histone deacetylase family protein 0.0018 0.0038 0.0163
Loa Loa (eye worm) hypothetical protein 0.0074 0.075 0.3224
Echinococcus granulosus histone deacetylase 8 0.0018 0.0038 0.0045
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Entamoeba histolytica hypothetical protein 0.0036 0.0266 0.0682
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0039 0.0109
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0314 0.2871
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.075 0.4561
Schistosoma mansoni adenoreceptor 0.0019 0.0048 0.0057
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0266 0.0266
Brugia malayi GnHR receptor homolog 0.0019 0.0048 0.0208
Onchocerca volvulus Alhambra homolog 0.0029 0.018 0.148
Echinococcus multilocularis histone deacetylase 8 0.0018 0.0038 0.0038
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0038 0.0045
Echinococcus granulosus g protein coupled receptor 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0033 0.0228 0.0228
Toxoplasma gondii histone deacetylase HDAC4 0.0018 0.0038 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0314 0.1352
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0024 0.0117 1
Brugia malayi Amidase family protein 0.0024 0.0117 0.0504
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0017 0.0031 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0112 0.0152
Brugia malayi Heterochromatin protein 1 0.0069 0.0689 0.2964
Echinococcus granulosus chromobox protein 1 0.0069 0.0689 0.0813
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.0057
Onchocerca volvulus Cell death protein 3 homolog 0.0024 0.012 0.0848
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.018 0.018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0314 0.1352
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0199 0.2326 0.2326
Loa Loa (eye worm) hypothetical protein 0.0029 0.018 0.0776
Loa Loa (eye worm) hypothetical protein 0.0039 0.0305 0.131
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Loa Loa (eye worm) hypothetical protein 0.0062 0.0598 0.2573
Echinococcus granulosus neuropeptide receptor 0.0019 0.0048 0.0057
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0314 0.0371
Plasmodium falciparum histone deacetylase 2 0.0018 0.0038 0.0129
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.005 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0268 0.2451
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0048 0.0048
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0112 0.0736
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.075 0.0884
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0689 0.2964
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0024 0.012 0.0805
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.3485 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0048 0.0057
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.1608 0.2745
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0337
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi Bromodomain containing protein 0.0031 0.0208 0.0893
Schistosoma mansoni neuropeptide receptor 0.0019 0.0048 0.0057
Plasmodium falciparum histone deacetylase, putative 0.0018 0.0038 0.0129
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0268 0.0688
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0048 0.0208
Brugia malayi hypothetical protein 0.0021 0.0078 0.0337
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0314 0.0371
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1001 0.2868
Toxoplasma gondii histone deacetylase HDAC1 0.0018 0.0038 0.0066
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0038 0.0038
Onchocerca volvulus 0.0019 0.0048 0.0109
Plasmodium vivax hypothetical protein, conserved 0.0024 0.012 0.1237
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0314 0.0371
Schistosoma mansoni tar DNA-binding protein 0.0063 0.061 0.0719
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Brugia malayi Nuclear hormone receptor E75 0.0019 0.005 0.0216
Schistosoma mansoni bromodomain containing protein 0.0059 0.0563 0.0664
Leishmania major histone deacetylase, putative 0.0018 0.0038 0.0066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0039 0.0109
Brugia malayi ecdysteroid receptor 0.004 0.0314 0.1352
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0039 0.0109
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0268 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.012 0.0339
Echinococcus granulosus fmrfamide receptor 0.0019 0.0048 0.0057
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0048 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0048 0.0057
Schistosoma mansoni biogenic amine receptor 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0064 0.0628 0.27
Mycobacterium tuberculosis Conserved protein 0.0074 0.075 0.1258
Echinococcus granulosus peregrin 0.0031 0.0208 0.0245
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0112 0.0516
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0314 0.0314
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0031 0.0084
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0017 0.0031 0.0031
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0048 0.0048
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0024 0.012 0.0141
Brugia malayi G-protein coupled receptor 0.0019 0.0048 0.0208
Schistosoma mansoni ap endonuclease 0.0017 0.0031 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0048 0.0208
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0078 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0038 0.0045
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0112 0.0516
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.1014 0.1195
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1001 0.2868
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.075 0.2149
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0112 0.0236
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0158
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0314 0.0371
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1314 0.5649
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0314 0.1352
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0017 0.0031 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0314 0.1352
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0314 0.1352
Brugia malayi histone deacetylase 11 0.0018 0.0038 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0305 0.0871
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0105 0.1137 0.134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0158
Schistosoma mansoni hypothetical protein 0.0407 0.4952 0.5838
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0162 0.046
Mycobacterium leprae Probable lipase LipE 0.0074 0.075 0.4265
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.0057
Onchocerca volvulus 0.0029 0.0175 0.1423
Loa Loa (eye worm) histone deacetylase 3 0.0062 0.0598 0.2573
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0598 0.1714
Loa Loa (eye worm) DR-78 0.0019 0.005 0.0216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0337
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0048 0.0057
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0257 0.0257
Schistosoma mansoni fatty-acid amide hydrolase 0.0024 0.0117 0.0138
Echinococcus granulosus histone deacetylase 1 0.0062 0.0598 0.0706
Entamoeba histolytica hypothetical protein 0.0036 0.0266 0.0682
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0048 0.0057
Schistosoma mansoni tar DNA-binding protein 0.0063 0.061 0.0719
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0048 0.0048
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0112 0.0482
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0314 0.0371
Schistosoma mansoni ap endonuclease 0.0017 0.0031 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0048 0.0048
Brugia malayi nuclear hormone receptor 0.0019 0.005 0.0216
Brugia malayi Bromodomain containing protein 0.007 0.0698 0.3
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0037 0.0085
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.075 0.0884
Brugia malayi beta-lactamase family protein 0.0074 0.075 0.3224
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0094 0.1001 0.4303
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0314 0.2871
Schistosoma mansoni histone deacetylase 1 2 3 0.0018 0.0038 0.0045
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0038 0.0038
Onchocerca volvulus 0.0019 0.0048 0.0109
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0598 0.1714
Brugia malayi hypothetical protein 0.0036 0.0266 0.1144
Trypanosoma cruzi metacaspase, putative 0.0024 0.012 0.0917
Plasmodium falciparum metacaspase 1 0.0024 0.012 0.1567
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0048 0.0057
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.075 0.075
Onchocerca volvulus 0.0019 0.0048 0.0109
Brugia malayi Histone deacetylase 1 0.0062 0.0598 0.2573
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus multilocularis histone deacetylase 3 0.0062 0.0598 0.0598
Echinococcus multilocularis microtubule associated protein 2 0.0686 0.8482 0.8482
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0048 0.0048
Giardia lamblia PHD finger protein 15 0.0029 0.018 0.0434
Leishmania major histone deacetylase, putative 0.0062 0.0598 0.5135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni hypothetical protein 0.0287 0.3433 0.4047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0094 0.1001 0.1001
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0598 0.1714
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0048 0.0057
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0048 0.0057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0024 0.012 0.012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0048 0.0208
Trypanosoma brucei histone deacetylase 3 0.0018 0.0038 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0056 0.0522 0.0522
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.005 0.0059
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0048 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0402 0.1149
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0048 0.0057
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.1001 1
Echinococcus granulosus dnaJ subfamily B 0.0407 0.4952 0.5838
Mycobacterium ulcerans aldehyde dehydrogenase 0.0105 0.1137 0.7013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Plasmodium vivax hypothetical protein, conserved 0.0074 0.075 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni amine GPCR 0.0019 0.0048 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0112 0.0516
Brugia malayi Dopamine receptor protein 1 0.0019 0.0048 0.0208
Trypanosoma brucei metacaspase MCA2 0.0024 0.012 0.0917
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0598 0.1714
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0048 0.0057
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0048 0.0057
Leishmania major hypothetical protein, conserved 0.0074 0.075 0.6504
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Mycobacterium ulcerans hypothetical protein 0.0074 0.075 0.4561
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0337
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0048 0.0057
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0112 0.0152
Echinococcus granulosus fatty acid amide hydrolase 1 0.0199 0.2326 0.2742
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0268 0.215
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0048 0.0057
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.0057
Trypanosoma brucei histone deacetylase 4 0.0018 0.0038 0.0076
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0016 0.0018 0.0018
Onchocerca volvulus 0.004 0.0314 0.2871
Toxoplasma gondii histone deacetylase HDAC5 0.0018 0.0038 0.0066
Schistosoma mansoni cpg binding protein 0.0029 0.0175 0.0206
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.057 0.2452
Echinococcus granulosus neuropeptide receptor 0.0019 0.0048 0.0057
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0268 0.215
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0268 0.0766
Brugia malayi neuropeptide F receptor 0.0019 0.0048 0.0208
Loa Loa (eye worm) TAR-binding protein 0.0063 0.061 0.2622
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi nuclear receptor NHR-88 0.004 0.0314 0.1352
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0268 0.2451
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.075 0.7415
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0314 0.0371
Echinococcus granulosus microtubule associated protein 2 0.0686 0.8482 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.018 0.1355
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0314 0.1352
Echinococcus multilocularis caspase 0.0024 0.012 0.012
Onchocerca volvulus 0.0019 0.0048 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0314 0.1352
Schistosoma mansoni cpg binding protein 0.0032 0.0218 0.0256
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0314 0.0371
Schistosoma mansoni histone deacetylase 0.0062 0.0598 0.0706
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0314 0.1352
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0024 0.0117 0.0161
Schistosoma mansoni amidase 0.0199 0.2326 0.2742
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0048 0.0048
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0066 0.0284
Schistosoma mansoni nuclear hormone receptor 0.0019 0.005 0.0059
Mycobacterium ulcerans beta-lactamase 0.0074 0.075 0.4561
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0048 0.0057
Loa Loa (eye worm) histone deacetylase 1 0.0062 0.0598 0.2573
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0078 0.0337
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.1861 0.2194
Mycobacterium ulcerans lipase LipD 0.0074 0.075 0.4561
Onchocerca volvulus 0.0019 0.0048 0.0109
Mycobacterium ulcerans hypothetical protein 0.0024 0.0112 0.0516
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0048 0.0057
Echinococcus multilocularis chromobox protein 1 0.0069 0.0689 0.0689
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.012 0.0339
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1001 0.2868
Brugia malayi Amidase family protein 0.0024 0.0117 0.0504
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.018 0.0213
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.005 0.0216
Brugia malayi amidase 0.0199 0.2326 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0038 0.0038
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.005 0.0127
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0314 0.0371
Toxoplasma gondii aldehyde dehydrogenase 0.0105 0.1137 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.075 0.1258
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0048 0.0057
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0314 0.1352
Brugia malayi hypothetical protein 0.0021 0.0078 0.0337
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0048 0.0057
Onchocerca volvulus 0.0074 0.075 0.7395
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0038 0.0045
Plasmodium falciparum phd finger protein, putative 0.0029 0.018 0.2638
Trypanosoma cruzi histone deacetylase 1, putative 0.0062 0.0598 0.5854
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0158
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0048 0.0048
Brugia malayi Cell death protein 3 precursor 0.0024 0.012 0.0514
Echinococcus granulosus jumonji domain containing protein 0.004 0.0324 0.0382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0048 0.0048
Brugia malayi histone deacetylase 1 (HD1) 0.0062 0.0598 0.2573
Trypanosoma brucei polo-like protein kinase 0.0094 0.1001 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Schistosoma mansoni neuropeptide receptor 0.0019 0.0048 0.0057
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0048 0.0057
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0048 0.0057
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0024 0.0117 0.0161
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.4952 0.4952
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.005 0.0059
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0314 0.0314
Echinococcus granulosus tar DNA binding protein 0.0063 0.061 0.0719
Mycobacterium ulcerans aldehyde dehydrogenase 0.0105 0.1137 0.7013
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0268 0.1154
Trypanosoma brucei histone deacetylase 1 0.0062 0.0598 0.5854
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus granulosus caspase 0.0024 0.012 0.0141
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0094 0.0094
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.075 0.2149
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Schistosoma mansoni chromobox protein 0.0069 0.0689 0.0813
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0048 0.0057
Trypanosoma brucei histone deacetylase, putative 0.0018 0.0038 0.0076
Schistosoma mansoni coup transcription factor 0.004 0.0314 0.0371
Mycobacterium ulcerans amidase 0.0024 0.0117 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0305 0.0871
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0024 0.0117 0.1204
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.075 0.2149
Brugia malayi RE15519p 0.0019 0.0048 0.0208
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0048 0.0048
Echinococcus multilocularis caspase 8 0.0024 0.012 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.1001 0.118
Brugia malayi jmjC domain containing protein 0.0038 0.03 0.129
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0094 0.1001 0.118
Echinococcus multilocularis peregrin 0.0031 0.0208 0.0208
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.005 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0018 0.0022
Schistosoma mansoni hypothetical protein 0.0019 0.0052 0.0061
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0266 0.0314
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.075 0.2149
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0048 0.0057
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0024 0.012 0.0805
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0314 0.0371
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.061 0.2622
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.075 0.2149
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0074 0.075 0.3224
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0038 0.0045
Loa Loa (eye worm) hypothetical protein 0.004 0.0325 0.1399
Brugia malayi G-protein coupled receptor 0.0019 0.0048 0.0208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0314 0.1352
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0017 0.0031 0.0132
Loa Loa (eye worm) hypothetical protein 0.0074 0.075 0.3224
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.1001 1
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0048 0.0057
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0024 0.0117 0.0251
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1314 0.5649
Trypanosoma cruzi amidase, putative 0.0024 0.0117 0.0892
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0024 0.012 0.0141
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0314 0.0371
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0266 0.0314
Toxoplasma gondii ABC1 family protein 0.0074 0.075 0.6504
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0314 0.1352
Schistosoma mansoni neuropeptide receptor 0.0019 0.0048 0.0057
Onchocerca volvulus 0.003 0.0199 0.1671
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0048 0.0057
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0048 0.0057
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.075 0.3224
Schistosoma mansoni caspase-7 (C14 family) 0.0024 0.012 0.0141
Echinococcus multilocularis cpg binding protein 0.0032 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Onchocerca volvulus 0.0019 0.0048 0.0109
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.1352
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0024 0.0117 0.0161
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0048 0.0057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0048 0.0048
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.3485 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0314 0.0371
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Plasmodium falciparum metacaspase-like protein 0.0024 0.012 0.1567
Loa Loa (eye worm) histone deacetylase 0.0018 0.0038 0.0163
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.005 0.0059
Mycobacterium ulcerans amidase 0.0024 0.0117 0.0549
Loa Loa (eye worm) RNA binding protein 0.0063 0.061 0.2622
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0048 0.0057
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0048 0.0048
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0024 0.0117 0.0117
Schistosoma mansoni alpha-glucosidase 0.0139 0.1576 0.1858
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0048 0.0057
Echinococcus multilocularis histone deacetylase 1 0.0062 0.0598 0.0598
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0048 0.0057
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.3485 1
Schistosoma mansoni hypothetical protein 0.0019 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0038 0.0163
Onchocerca volvulus 0.0019 0.005 0.0127
Onchocerca volvulus 0.0019 0.0048 0.0109
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0024 0.0117 0.1525
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.075 0.7415
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0314 0.1352
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0048 0.0057
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0598 0.1714
Entamoeba histolytica serine/threonine protein kinase, putative 0.0094 0.1001 0.2808
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0039 0.0109
Loa Loa (eye worm) hypothetical protein 0.003 0.0199 0.0855
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0314 0.0314
Brugia malayi ecdysone receptor 0.0019 0.005 0.0216
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0037 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0048 0.0057
Brugia malayi nuclear receptor RXR 0.0019 0.005 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.012 0.0339
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0048 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0268 0.0766
Schistosoma mansoni neuropeptide receptor 0.0019 0.0048 0.0057
Plasmodium vivax histone deacetylase 2, putative 0.0018 0.0038 0.0102
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0024 0.012 0.0805
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.075 0.1258
Schistosoma mansoni zinc finger protein 0.0019 0.005 0.0059
Brugia malayi steroid hormone receptor 0.004 0.0314 0.1352
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0314 0.1352
Brugia malayi Melatonin receptor type 1A 0.0019 0.0048 0.0208
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.005 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0314 0.1352
Loa Loa (eye worm) hypothetical protein 0.0024 0.0112 0.0482
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0048 0.0048
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0048 0.0048
Onchocerca volvulus 0.0019 0.0048 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0314 0.1352
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.1608 1
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0598 0.1714
Loa Loa (eye worm) bromodomain containing protein 0.0016 0.0017 0.0075
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0048 0.0057
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0033 0.0228 0.0268
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0048 0.0057
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0048 0.0057
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0078 0.0092
Onchocerca volvulus 0.0019 0.0048 0.0109
Schistosoma mansoni zinc finger protein 0.0019 0.006 0.0071
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0048 0.0048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0024 0.0028
Mycobacterium tuberculosis Conserved protein 0.0074 0.075 0.1258
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.018 0.0776
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0024 0.0117 0.0161
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0268 0.0688
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Loa Loa (eye worm) amidase 0.0024 0.0117 0.0504
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0048 0.0048
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.1608 1
Brugia malayi CXXC zinc finger family protein 0.0029 0.0175 0.0752
Mycobacterium tuberculosis Conserved protein 0.0074 0.075 0.1258
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1001 0.2868
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni alpha glucosidase 0.0036 0.0268 0.0316
Loa Loa (eye worm) hypothetical protein 0.0024 0.012 0.0514
Brugia malayi hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0078 0.0337
Loa Loa (eye worm) hypothetical protein 0.0019 0.005 0.0216
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0342 0.0978
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.061 0.2622
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.005 0.0059
Loa Loa (eye worm) beta-lactamase 0.0074 0.075 0.3224
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.012 0.0339
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0314 0.1352
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0094 0.0111
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0048 0.0057
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0038 0.0076
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0048 0.0048
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0314 0.0314
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1001 0.2868
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0048 0.0048
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Plasmodium vivax histone deacetylase, putative 0.0018 0.0038 0.0102
Echinococcus granulosus caspase 8 0.0024 0.012 0.0141
Brugia malayi hypothetical protein 0.0019 0.005 0.0216
Onchocerca volvulus 0.0019 0.005 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0039 0.0109
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0048 0.0057
Trypanosoma cruzi metacaspase 5, putative 0.0024 0.012 0.0917
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0314 0.1352
Echinococcus granulosus histone deacetylase 6 0.0018 0.0038 0.0045
Plasmodium vivax metacaspase 1, putative 0.0024 0.012 0.1237
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0048 0.0057
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0048 0.0208
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0024 0.0117 0.0138
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0052 0.0222
Brugia malayi Serotonin receptor 0.0019 0.0048 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Brugia malayi Histone deacetylase family protein 0.0018 0.0038 0.0163
Trypanosoma brucei histone deacetylase 2 0.0018 0.0038 0.0076
Entamoeba histolytica hypothetical protein 0.0036 0.0266 0.0682
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0048 0.0208
Brugia malayi beta-lactamase family protein 0.0074 0.075 0.3224
Echinococcus granulosus X box binding protein 1 0.0287 0.3433 0.4047
Brugia malayi neuropeptide F receptor 0.0019 0.0048 0.0208
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0048 0.0208
Echinococcus granulosus orexin receptor type 2 0.0019 0.0048 0.0057
Schistosoma mansoni nuclear hormone receptor 0.004 0.0314 0.0371
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0094 0.1001 0.8772
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0024 0.012 0.0514
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0268 0.0766
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0048 0.0208
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0094 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.012 0.0339
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0024 0.0117 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0048 0.0048
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.005 0.0216
Trypanosoma brucei Metacaspase-4 0.0024 0.012 0.0917
Mycobacterium ulcerans amidase 0.0024 0.0117 0.0549
Schistosoma mansoni microtubule-associated protein tau 0.0686 0.8482 1
Onchocerca volvulus 0.0019 0.0048 0.0109
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0314 0.0371
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.075 0.1258
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Brugia malayi serine/threonine-protein kinase plk-2 0.0094 0.1001 0.4303
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0105 0.1137 0.1928
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0158
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0038 0.0076
Schistosoma mansoni nuclear receptor 0.0019 0.005 0.0059
Onchocerca volvulus 0.0019 0.0048 0.0109
Loa Loa (eye worm) histone deacetylase 11 0.0018 0.0038 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.012 0.0514
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.075 0.3224
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0024 0.012 0.0339
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0048 0.0057
Schistosoma mansoni biogenic amine receptor 0.0019 0.0048 0.0057
Brugia malayi beta-lactamase 0.0074 0.075 0.3224
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0074 0.075 0.3224
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0324 0.0324
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0048 0.0048
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0314 0.0314
Brugia malayi G protein-coupled receptor 0.0019 0.0048 0.0208
Onchocerca volvulus 0.0074 0.075 0.7395
Brugia malayi sulfakinin receptor protein 0.0019 0.0048 0.0208
Trypanosoma brucei metacaspase 5, putative 0.0024 0.012 0.0917
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.03 0.0354
Echinococcus granulosus g protein coupled receptor 0.0019 0.0048 0.0057
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.075 0.0884
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.075 0.1258
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0112 0.0516
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0048 0.0109
Trypanosoma brucei glucosidase, putative 0.0036 0.0268 0.2451
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0767 0.0904
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0048 0.0057
Schistosoma mansoni aldehyde dehydrogenase 0.0105 0.1137 0.134
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0048 0.0057
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0598 0.1714
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0038 0.0076
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.012 0.0339
Onchocerca volvulus 0.0094 0.0998 0.997
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0024 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0208
Echinococcus granulosus g protein coupled receptor 0.0019 0.0048 0.0057
Schistosoma mansoni caspase-7 (C14 family) 0.0024 0.012 0.0141
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0048 0.0208
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3485 1
Echinococcus multilocularis sex peptide receptor 0.0019 0.0048 0.0048
Schistosoma mansoni amine GPCR 0.0019 0.0048 0.0057
Schistosoma mansoni thyroid hormone receptor 0.004 0.0314 0.0371
Leishmania major hypothetical protein, conserved 0.0024 0.0117 0.0783
Mycobacterium ulcerans amidase 0.0024 0.0117 0.0549
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.005 0.0216
Schistosoma mansoni amine GPCR 0.0019 0.0048 0.0057
Schistosoma mansoni hypothetical protein 0.0036 0.0266 0.0314
Echinococcus granulosus histone deacetylase 7 0.0018 0.0038 0.0045
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0525 0.447
Loa Loa (eye worm) hypothetical protein 0.0037 0.0283 0.1216
Echinococcus granulosus hypothetical protein 0.0019 0.0048 0.0057

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 20.6 % Blockade of human recombinant NR1/NR2A expressed in xenopus oocytes assessed as inhibition of L-glutamate/glycine-induced whole-cell current at 10 uM at holding potential of -60 mV by by electrophysiological assay relative to control ChEMBL. 21612926
Inhibition (binding) = 44.8 % Blockade of rat recombinant TRPV1 expressed in xenopus oocytes assessed as inhibition of capsaicin-induced whole-cell current at 10 uM at holding potential of -60 mV by by electrophysiological assay relative to control ChEMBL. 21612926

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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