Detailed information for compound 1560535

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 387.43 | Formula: C20H25N3O5
  • H donors: 1 H acceptors: 4 LogP: -0.14 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@]1(N[C@@H]([C@H]2[C@@H]1C(=O)N(C2=O)C)CN(C(=O)C)C)Cc1ccccc1
  • InChi: 1S/C20H25N3O5/c1-12(24)22(2)11-14-15-16(18(26)23(3)17(15)25)20(21-14,19(27)28-4)10-13-8-6-5-7-9-13/h5-9,14-16,21H,10-11H2,1-4H3/t14-,15+,16-,20-/m1/s1
  • InChiKey: BNFGLYRQZQBSGB-UIVXKWKOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Steroid receptor seven-up type 2 0.0057 0.032 0.0537
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0057 0.032 0.0307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.025 0.1937 0.3372
Loa Loa (eye worm) hypothetical protein 0.025 0.1937 0.3372
Echinococcus multilocularis ecdysone induced protein 78C 0.0057 0.032 0.0307
Schistosoma mansoni ap endonuclease 0.0038 0.0158 0.0146
Mycobacterium ulcerans carboxylesterase, LipT 0.0118 0.0832 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.1436
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0057 0.032 0.0537
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0503 0.049
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.003 0.0093 0.008
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.1101
Plasmodium falciparum acyl-CoA synthetase 0.0088 0.0574 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0088 0.0574 1
Schistosoma mansoni sodium-dependent amino acid transporter 0.0042 0.0189 0.0176
Echinococcus granulosus BC026374 protein S09 family 0.0118 0.0832 0.082
Schistosoma mansoni hypothetical protein 0.0039 0.017 0.0158
Loa Loa (eye worm) hypothetical protein 0.0699 0.572 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0189 0.0176
Schistosoma mansoni nuclear receptor 0.0027 0.0065 0.0053
Leishmania major importin beta-1 subunit, putative 0.0023 0.0031 0.0219
Brugia malayi nuclear receptor NHR-88 0.0057 0.032 0.0537
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.003 0.0093 0.008
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0158 0.1794
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0128 0.054
Plasmodium falciparum transporter, putative 0.0042 0.0189 0.3138
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0118 0.0832 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0117 0.0823 0.9883
Entamoeba histolytica hypothetical protein 0.0023 0.0031 0.0219
Brugia malayi ecdysone receptor 0.0027 0.0065 0.0092
Echinococcus multilocularis serotonin transporter 0.0246 0.1904 0.1894
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.003 0.0093 0.008
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.014
Echinococcus granulosus FTZ F1 alpha 0.0057 0.032 0.0307
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0246 0.1904 0.1894
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0158 0.0255
Schistosoma mansoni nuclear receptor 0.0027 0.0065 0.0053
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Toxoplasma gondii hypothetical protein 0.0042 0.0189 0.1497
Loa Loa (eye worm) hypothetical protein 0.0079 0.0503 0.0858
Brugia malayi hypothetical protein 0.0064 0.0374 0.0633
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0641 0.1101
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0128 0.054
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0088 0.0574 0.654
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.032 0.0307
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0057 0.032 0.0307
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0189 0.0176
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0057 0.032 0.0307
Brugia malayi CHE-14 protein 0.0041 0.0183 0.0298
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0034 0.0128 0.0201
Echinococcus multilocularis snurportin 1 0.0301 0.237 0.236
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0059 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0057 0.032 0.0537
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0189 0.0176
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1952 0.1941
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0189 0.0176
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.1436
Brugia malayi nuclear receptor NHR-88 0.0027 0.0065 0.0092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.0309
Brugia malayi Carboxylesterase family protein 0.0699 0.572 1
Brugia malayi nuclear receptor RXR 0.003 0.0093 0.014
Loa Loa (eye worm) hypothetical protein 0.0117 0.0823 0.142
Echinococcus multilocularis protein patched 0.0041 0.0183 0.017
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0189 0.0176
Plasmodium vivax amine transporter, putative 0.0042 0.0189 0.3138
Mycobacterium tuberculosis Carboxylesterase LipT 0.0118 0.0832 1
Onchocerca volvulus 0.0057 0.032 0.1382
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.0823 0.9877
Brugia malayi Importin beta-1 subunit 0.0028 0.0075 0.011
Loa Loa (eye worm) hypothetical protein 0.0117 0.0823 0.142
Onchocerca volvulus 0.0038 0.0159 0.051
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0128 0.0201
Echinococcus multilocularis FTZ F1 alpha 0.0057 0.032 0.0307
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0042 0.0189 0.0176
Brugia malayi photoreceptor-specific nuclear receptor 0.0057 0.032 0.0537
Plasmodium vivax acyl-CoA synthetase, putative 0.0088 0.0574 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0189 0.0176
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.0823 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0057 0.032 0.0307
Loa Loa (eye worm) norepinephrine transporter 0.0246 0.1904 0.3315
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0057 0.032 0.0307
Onchocerca volvulus 0.0118 0.0832 0.4169
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0128 0.054
Echinococcus multilocularis expressed conserved protein 0.009 0.0592 0.058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.032 0.0307
Onchocerca volvulus 0.0246 0.1904 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0158 0.0436
Entamoeba histolytica hypothetical protein 0.0073 0.045 0.5398
Schistosoma mansoni hypothetical protein 0.0301 0.237 0.236
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0075 0.0532
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0158 0.259
Echinococcus multilocularis para nitrobenzyl esterase 0.0118 0.0832 0.082
Schistosoma mansoni hypothetical protein 0.0079 0.0503 0.049
Schistosoma mansoni hypothetical protein 0.0073 0.045 0.0438
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1952 0.1941
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0183 0.2197
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.032 0.0537
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0534 0.6
Loa Loa (eye worm) nuclear receptor NHR-67 0.0027 0.0065 0.0092
Loa Loa (eye worm) hypothetical protein 0.0229 0.1766 0.3073
Brugia malayi nuclear hormone receptor 0.0057 0.032 0.0537
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0117 0.0823 0.9877
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0027 0.0065 0.0092
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.2773
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0699 0.572 0.5714
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.025 0.1937 0.3372
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.045 0.0438
Loa Loa (eye worm) hypothetical protein 0.0088 0.0574 0.0984
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0128 0.054
Echinococcus granulosus ecdysone induced protein 78C 0.0057 0.032 0.0307
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0309
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0158 0.0146
Echinococcus granulosus serotonin transporter 0.0246 0.1904 0.1894
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0309
Loa Loa (eye worm) hypothetical protein 0.005 0.026 0.0434
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0236 0.0391
Loa Loa (eye worm) oxidoreductase 0.0034 0.0128 0.0201
Echinococcus granulosus acetylcholinesterase 0.0699 0.572 0.5714
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0031 0.0368
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0128 0.1415
Echinococcus multilocularis tar DNA binding protein 0.0251 0.1952 0.1941
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Loa Loa (eye worm) hypothetical protein 0.0246 0.1904 0.3315
Echinococcus multilocularis protein dispatched 1 0.0047 0.0231 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0057 0.032 0.0537
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0128 0.0201
Loa Loa (eye worm) DR-78 0.0027 0.0065 0.0092
Schistosoma mansoni cpg binding protein 0.0085 0.0552 0.054
Brugia malayi hypothetical protein 0.0027 0.0065 0.0092
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0027 0.0065 0.0053
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.0521 0.0508
Brugia malayi RNA, U transporter 1 0.008 0.0513 0.0876
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.2773
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0641 0.775
Onchocerca volvulus 0.0042 0.0189 0.0673
Brugia malayi Carboxylesterase family protein 0.0118 0.0832 0.1436
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0053 0.0343
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0093 0.014
Echinococcus granulosus nuclear receptor nhr 48 0.0027 0.0065 0.0053
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0093 0.014
Schistosoma mansoni nuclear hormone receptor 0.0057 0.032 0.0307
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0034 0.0128 0.7886
Brugia malayi ecdysteroid receptor 0.0057 0.032 0.0537
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0641 0.0629
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1952 0.1941
Brugia malayi RNA binding protein 0.0251 0.1952 0.3397
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0042 0.0189 0.0176
Loa Loa (eye worm) hypothetical protein 0.0246 0.1904 0.3315
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Brugia malayi conserved hypotetical protein 0.0027 0.0065 0.0092
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0059 0.0046
Loa Loa (eye worm) hypothetical protein 0.0034 0.0128 0.0201
Echinococcus granulosus geminin 0.0665 0.5429 0.5423
Echinococcus multilocularis nuclear receptor nhr 48 0.0027 0.0065 0.0053
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0034 0.0128 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0534 0.6
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0031 0.0368
Loa Loa (eye worm) steroid hormone receptor 0.0057 0.032 0.0537
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0034 0.0128 0.054
Echinococcus granulosus cpg binding protein 0.009 0.0593 0.058
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0503 0.0858
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0158 0.1903
Loa Loa (eye worm) hypothetical protein 0.0246 0.1904 0.3315
Schistosoma mansoni hypothetical protein 0.0039 0.017 0.0158
Onchocerca volvulus 0.0085 0.0552 0.2645
Schistosoma mansoni coup transcription factor 0.0057 0.032 0.0307
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0158 1
Brugia malayi hypothetical protein 0.003 0.0093 0.014
Brugia malayi hypothetical protein 0.0229 0.1766 0.3073
Echinococcus multilocularis acetylcholinesterase 0.0699 0.572 0.5714
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.032 0.0537
Brugia malayi nuclear hormone receptor 0.0027 0.0065 0.0092
Plasmodium vivax acetyl-CoA synthetase, putative 0.0034 0.0128 0.2043
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0053 0.2773
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0189 0.3138
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0503 0.049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0065 0.0053
Brugia malayi hypothetical protein 0.0026 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0309
Loa Loa (eye worm) hypothetical protein 0.0171 0.1273 0.2209
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0065 0.0053
Schistosoma mansoni thyroid hormone receptor 0.0057 0.032 0.0307
Trichomonas vaginalis ran, putative 0.0021 0.0013 0.0155
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.0521 0.0508
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0042 0.0189 0.0176
Loa Loa (eye worm) nuclear hormone receptor 0.0027 0.0065 0.0092
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Schistosoma mansoni survival motor neuron protein 0.0047 0.0232 0.0219
Onchocerca volvulus 0.0117 0.0823 0.4122
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0065 0.0092
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.045 0.0438
Schistosoma mansoni hypothetical protein 0.0665 0.5429 0.5423
Brugia malayi orphan nuclear receptor NR2E1 0.0027 0.0065 0.0092
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0034 0.0128 0.0974
Brugia malayi tailless protein 0.0027 0.0065 0.0092
Loa Loa (eye worm) hypothetical protein 0.0034 0.0128 0.0201
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0034 0.0128 0.0201
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.032 0.0537
Schistosoma mansoni hypothetical protein 0.0665 0.5429 0.5423
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0027 0.0065 0.0053
Loa Loa (eye worm) hypothetical protein 0.0117 0.0823 0.142
Echinococcus multilocularis BC026374 protein (S09 family) 0.0118 0.0832 0.082
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0065 0.0092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Onchocerca volvulus 0.0042 0.0189 0.0673
Leishmania major acetyl-CoA synthetase, putative 0.0034 0.0128 0.1415
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Loa Loa (eye worm) hypothetical protein 0.0068 0.0407 0.0691
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0057 0.032 0.0537
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0653 0.0641
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0034 0.0128 0.0974
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0057 0.032 0.0537
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.014
Loa Loa (eye worm) hypothetical protein 0.0252 0.196 0.3412
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.045 0.0438
Echinococcus granulosus expressed conserved protein 0.009 0.0592 0.058
Schistosoma mansoni RAR-like nuclear receptor 0.0057 0.032 0.0307
Plasmodium falciparum amino acid transporter, putative 0.0042 0.0189 0.3138
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.1436
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0118 0.0832 0.082
Plasmodium vivax importin-beta 2, putative 0.0028 0.0075 0.1115
Schistosoma mansoni hypothetical protein 0.0047 0.0232 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Schistosoma mansoni thyroid hormone receptor 0.0057 0.032 0.0307
Brugia malayi AMP-binding enzyme family protein 0.0117 0.0823 0.142
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.0823 1
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0183 0.017
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0251 0.1952 0.3397
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Onchocerca volvulus 0.0118 0.0832 0.4169
Echinococcus multilocularis thyroid hormone receptor alpha 0.0057 0.032 0.0307
Loa Loa (eye worm) RNA binding protein 0.0251 0.1952 0.3397
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1952 0.1941
Brugia malayi AMP-binding enzyme family protein 0.0117 0.0823 0.142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.032 0.0537
Schistosoma mansoni hypothetical protein 0.0039 0.017 0.0158
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.1436
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0183 0.0298
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0065 0.0053
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0117 0.0823 0.9883
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0503 0.049
Loa Loa (eye worm) hypothetical protein 0.0136 0.0978 0.1692
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0158 0.0146
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0503 0.0858
Echinococcus granulosus GPCR family 2 0.0079 0.0503 0.049
Brugia malayi CXXC zinc finger family protein 0.0085 0.0552 0.0944
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0128 0.7886
Echinococcus multilocularis acetylcholinesterase 0.0699 0.572 0.5714
Toxoplasma gondii histone lysine methyltransferase SET1 0.0161 0.119 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0158 0.1794
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0034 0.0128 0.054
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.0309
Plasmodium falciparum importin beta, putative 0.0028 0.0075 0.1115
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0503 0.0858
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0232 0.0383
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Schistosoma mansoni hypothetical protein 0.0066 0.0393 0.038
Echinococcus multilocularis neuroligin 0.0118 0.0832 0.082
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0118 0.0832 0.082
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.014
Onchocerca volvulus 0.0047 0.0232 0.0904
Onchocerca volvulus Bile acid receptor homolog 0.0057 0.032 0.1382
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0118 0.0832 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0117 0.0823 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Echinococcus granulosus jun protein 0.0081 0.0521 0.0508
Schistosoma mansoni sodium/chloride dependent transporter 0.0246 0.1904 0.1894
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0309
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.1436
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0031 0.0368
Loa Loa (eye worm) hypothetical protein 0.0028 0.0075 0.011
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.0823 0.9877
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0016 0.0003
Schistosoma mansoni hypothetical protein 0.1208 1 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Trichomonas vaginalis spcc417.12 protein, putative 0.0118 0.0832 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0027 0.0065 0.0092
Leishmania major acetyl-CoA synthetase, putative 0.0034 0.0128 0.1415
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Schistosoma mansoni ap endonuclease 0.0038 0.0158 0.0146
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.014
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.014
Echinococcus granulosus microtubule associated protein 2 0.0669 0.5465 0.5459
Toxoplasma gondii exonuclease III APE 0.0038 0.0158 0.1235
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0158 0.0255
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0118 0.0832 0.082
Treponema pallidum sodium- and chloride- dependent transporter 0.0246 0.1904 1
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.1273 0.2209
Schistosoma mansoni acetyl-CoA synthetase 0.0034 0.0128 0.0115
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0128 0.7886
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0034 0.0128 0.054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0057 0.032 0.0537
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.1497
Trichomonas vaginalis antibiotic synthetase, putative 0.0034 0.0128 0.1533
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0016 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0158 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0986 0.0974
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0034 0.0128 0.054
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0309
Echinococcus multilocularis geminin 0.0665 0.5429 0.5423
Entamoeba histolytica acyl-CoA synthetase, putative 0.0117 0.0823 1
Entamoeba histolytica hypothetical protein 0.0073 0.045 0.5398
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0158 0.0953
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0016 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0856 0.1477
Schistosoma mansoni BC026374 protein (S09 family) 0.0118 0.0832 0.082
Loa Loa (eye worm) hypothetical protein 0.0041 0.0183 0.0298
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0031 0.1221
Schistosoma mansoni nuclear receptor nhr-48 0.0027 0.0065 0.0053
Onchocerca volvulus 0.0034 0.0128 0.0338
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.032 0.0307
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.1766 0.1756
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0057 0.032 0.0537
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0016 0.0003
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0117 0.0823 0.9877
Echinococcus multilocularis cpg binding protein 0.009 0.0593 0.058
Entamoeba histolytica hypothetical protein 0.0073 0.045 0.5398
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0189 0.0176
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0065 0.0053
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0718
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1952 0.1941
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0857
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0057 0.032 0.0307
Brugia malayi hypothetical protein 0.0042 0.0189 0.0309
Brugia malayi RNA recognition motif domain containing protein 0.0251 0.1952 0.3397
Leishmania major hypothetical protein, conserved 0.0026 0.0053 0.0498
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0158 0.259
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0158 0.1903
Entamoeba histolytica acyl-CoA synthetase, putative 0.0117 0.0823 1
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0034 0.0128 0.0115
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0189 0.0176
Toxoplasma gondii hypothetical protein 0.0042 0.0189 0.1497
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0158 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0057 0.032 0.0537
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0034 0.0128 0.054
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0118 0.0832 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0057 0.032 0.0307
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0189 0.0176
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0158 0.5
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0057 0.032 0.0307
Brugia malayi steroid hormone receptor 0.0057 0.032 0.0537
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0641 0.0629
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Onchocerca volvulus 0.0064 0.0374 0.1679
Schistosoma mansoni microtubule-associated protein tau 0.0669 0.5465 0.5459
Echinococcus granulosus acetylcholinesterase 0.0699 0.572 0.5714
Schistosoma mansoni importin beta-1 0.0028 0.0075 0.0063
Schistosoma mansoni hypothetical protein 0.0039 0.017 0.0158
Brugia malayi hypothetical protein 0.0118 0.0832 0.1436
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.003 0.0093 0.014
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0053 0.0718
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0986 0.0974
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0088 0.0574 0.6342
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0057 0.032 0.0537
Brugia malayi TAR-binding protein 0.0251 0.1952 0.3397
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0128 0.0201
Echinococcus multilocularis microtubule associated protein 2 0.0669 0.5465 0.5459
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0534 0.6
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0034 0.0128 0.2043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0093 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0057 0.032 0.0537
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Echinococcus granulosus para nitrobenzyl esterase 0.0118 0.0832 0.082
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0057 0.032 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0057 0.032 0.0537
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0118 0.0832 0.082
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0128 0.0201
Brugia malayi Calcitonin receptor-like protein seb-1 0.025 0.1937 0.3372
Schistosoma mansoni hypothetical protein 0.0171 0.1273 0.1262
Onchocerca volvulus 0.0118 0.0832 0.4169
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.032 0.0537
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0075 0.4305
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.032 0.0537
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0016 0.0003
Mycobacterium ulcerans hypothetical protein 0.0117 0.0823 0.9877
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0189 0.0176
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0158 1
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Trichomonas vaginalis antibiotic synthetase, putative 0.0034 0.0128 0.1533
Brugia malayi Cytochrome P450 family protein 0.0047 0.0236 0.0391
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0071
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Schistosoma mansoni mixed-lineage leukemia protein mll 0.018 0.1352 0.1341
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0118 0.0832 0.082
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0034 0.0128 0.0201
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.1436
Schistosoma mansoni cpg binding protein 0.009 0.0593 0.058
Brugia malayi hypothetical protein 0.0073 0.045 0.0767
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0056 0.0076
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0034 0.0128 0.7886
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.032 0.0307
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0718
Onchocerca volvulus 0.0118 0.0832 0.4169
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.0309
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0057 0.032 0.0537
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0552 0.0944
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0309
Loa Loa (eye worm) serotonin transporter b 0.0246 0.1904 0.3315
Schistosoma mansoni cpg binding protein 0.009 0.0593 0.058
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0057 0.032 0.0307
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0075 0.4305
Loa Loa (eye worm) carboxylesterase 0.0699 0.572 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Loa Loa (eye worm) carboxylesterase 0.0118 0.0832 0.1436
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0034 0.0128 0.7886
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0027 0.0065 0.0053
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0057 0.032 0.0307
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0128 0.7886
Brugia malayi nuclear hormone receptor family member nhr-6 0.0027 0.0065 0.0092
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.0823 1
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0065 0.0053
Echinococcus granulosus carboxylesterase 5A 0.0699 0.572 0.5714
Brugia malayi Carboxylesterase family protein 0.0118 0.0832 0.1436
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.032 0.0307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0057 0.032 0.0537
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0065 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0057 0.032 0.0537
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0117 0.0823 1
Loa Loa (eye worm) solute carrier family 6 member 4 0.0246 0.1904 0.3315
Schistosoma mansoni patched 1 0.0041 0.0183 0.017
Echinococcus granulosus snurportin 1 0.0301 0.237 0.236
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0034 0.0128 0.0201
Schistosoma mansoni neuroligin 3 (S09 family) 0.0118 0.0832 0.082
Echinococcus multilocularis GPCR, family 2 0.0079 0.0503 0.049
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0183 0.017
Loa Loa (eye worm) carboxylesterase 0.0118 0.0832 0.1436
Loa Loa (eye worm) hypothetical protein 0.0088 0.0574 0.0984
Brugia malayi AMP-binding enzyme family protein 0.0117 0.0823 0.142
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0065 0.0053
Echinococcus granulosus tar DNA binding protein 0.0251 0.1952 0.1941
Brugia malayi bZIP transcription factor family protein 0.0081 0.0521 0.089
Onchocerca volvulus Protein ultraspiracle homolog 0.0057 0.032 0.1382
Schistosoma mansoni retinoic acid receptor RXR 0.0057 0.032 0.0307
Brugia malayi nuclear receptor NHR-67 0.0027 0.0065 0.0092
Brugia malayi nuclear receptor RXR 0.0027 0.0065 0.0092
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0301 0.237 0.413
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0034 0.0128 0.1415
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0057 0.032 0.0307
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0503 0.049
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.0823 0.9877
Onchocerca volvulus 0.0034 0.0128 0.0338
Brugia malayi MH2 domain containing protein 0.0121 0.0856 0.1477
Onchocerca volvulus 0.0034 0.0128 0.0338
Onchocerca volvulus 0.0118 0.0832 0.4169
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0065 0.0053
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0057 0.032 0.1382
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0183 0.017
Loa Loa (eye worm) TAR-binding protein 0.0251 0.1952 0.3397
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0092
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0075 0.0063
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0117 0.082 0.0808
Brugia malayi Carboxylesterase family protein 0.0118 0.0832 0.1436
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0309
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0034 0.0128 0.054
Loa Loa (eye worm) hypothetical protein 0.0057 0.032 0.0537
Onchocerca volvulus 0.0042 0.0189 0.0673
Echinococcus multilocularis dnaJ subfamily B 0.1208 1 1
Schistosoma mansoni jun-related protein 0.0066 0.0393 0.038
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0117 0.0823 1
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0042 0.0189 0.0309
Schistosoma mansoni steroid hormone receptor ad4bp 0.0057 0.032 0.0307
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.0309
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0189 0.0176
Schistosoma mansoni hypothetical protein 0.0079 0.0503 0.049
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.1497
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.032 0.0537
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0117 0.0823 0.9877
Schistosoma mansoni hypothetical protein 0.0079 0.0503 0.049
Loa Loa (eye worm) hypothetical protein 0.0699 0.572 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0246 0.1904 0.3315
Loa Loa (eye worm) acetylcholinesterase 1 0.0699 0.572 1
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0856 0.1477
Entamoeba histolytica hypothetical protein 0.0073 0.045 0.5398
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0027 0.0065 0.0053
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0059 0.0046
Loa Loa (eye worm) hypothetical protein 0.0088 0.0574 0.0984
Brugia malayi Amyloid A4 extracellular domain containing protein 0.032 0.2531 0.4412
Echinococcus granulosus thyroid hormone receptor alpha 0.0027 0.0065 0.0053
Brugia malayi Carboxylesterase family protein 0.0699 0.572 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0574 0.0984
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.1436
Loa Loa (eye worm) hypothetical protein 0.0088 0.0574 0.0984
Brugia malayi hypothetical protein 0.0027 0.0065 0.0092
Schistosoma mansoni acetylcholinesterase 0.0118 0.0832 0.082
Echinococcus granulosus importin subunit beta 1 0.0028 0.0075 0.0063
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0057 0.032 0.0307
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.1766 0.1756
Echinococcus granulosus neuroligin 0.0118 0.0832 0.082
Schistosoma mansoni gliotactin 0.0118 0.0832 0.082
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0117 0.0823 0.9877
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0057 0.032 0.0307
Brugia malayi hypothetical protein 0.003 0.0093 0.014
Brugia malayi Carboxylesterase family protein 0.0118 0.0832 0.1436
Toxoplasma gondii propionate-CoA ligase 0.0034 0.0128 0.0974
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.0309
Schistosoma mansoni zinc finger protein 0.0027 0.0065 0.0053
Echinococcus multilocularis jun protein 0.0081 0.0521 0.0508
Echinococcus multilocularis carboxylesterase 5A 0.0699 0.572 0.5714
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0027 0.0065 0.0092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0534 0.6
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0027 0.0065 0.0053
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0034 0.0128 0.054
Schistosoma mansoni hypothetical protein 0.0079 0.0503 0.049
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0189 0.1497

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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